Amino acid dipepetide frequency for Trichoderma arundinaceum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.201AlaAla: 10.201 ± 0.071	1.053AlaCys: 1.053 ± 0.015	4.471AlaAsp: 4.471 ± 0.03	5.265AlaGlu: 5.265 ± 0.042	3.171AlaPhe: 3.171 ± 0.027	5.936AlaGly: 5.936 ± 0.044	1.81AlaHis: 1.81 ± 0.021	4.613AlaIle: 4.613 ± 0.033	4.28AlaLys: 4.28 ± 0.037	7.843AlaLeu: 7.843 ± 0.047	2.049AlaMet: 2.049 ± 0.023	3.13AlaAsn: 3.13 ± 0.028	4.897AlaPro: 4.897 ± 0.047	3.549AlaGln: 3.549 ± 0.035	4.909AlaArg: 4.909 ± 0.036	7.725AlaSer: 7.725 ± 0.043	5.354AlaThr: 5.354 ± 0.037	5.583AlaVal: 5.583 ± 0.041	1.205AlaTrp: 1.205 ± 0.024	2.191AlaTyr: 2.191 ± 0.021	0.001AlaXaa: 0.001 ± 0.001
Cys	0.901CysAla: 0.901 ± 0.015	0.234CysCys: 0.234 ± 0.008	0.648CysAsp: 0.648 ± 0.013	0.569CysGlu: 0.569 ± 0.011	0.542CysPhe: 0.542 ± 0.013	0.92CysGly: 0.92 ± 0.015	0.321CysHis: 0.321 ± 0.009	0.709CysIle: 0.709 ± 0.011	0.483CysLys: 0.483 ± 0.011	1.179CysLeu: 1.179 ± 0.014	0.247CysMet: 0.247 ± 0.007	0.428CysAsn: 0.428 ± 0.012	0.616CysPro: 0.616 ± 0.013	0.441CysGln: 0.441 ± 0.009	0.701CysArg: 0.701 ± 0.013	0.895CysSer: 0.895 ± 0.016	0.645CysThr: 0.645 ± 0.012	0.754CysVal: 0.754 ± 0.013	0.196CysTrp: 0.196 ± 0.006	0.336CysTyr: 0.336 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.032AspAla: 5.032 ± 0.031	0.621AspCys: 0.621 ± 0.011	4.525AspAsp: 4.525 ± 0.044	4.658AspGlu: 4.658 ± 0.042	2.245AspPhe: 2.245 ± 0.019	4.33AspGly: 4.33 ± 0.036	1.198AspHis: 1.198 ± 0.016	3.251AspIle: 3.251 ± 0.029	2.562AspLys: 2.562 ± 0.024	4.978AspLeu: 4.978 ± 0.041	1.305AspMet: 1.305 ± 0.017	1.969AspAsn: 1.969 ± 0.023	3.15AspPro: 3.15 ± 0.024	1.819AspGln: 1.819 ± 0.018	2.951AspArg: 2.951 ± 0.032	4.18AspSer: 4.18 ± 0.035	2.81AspThr: 2.81 ± 0.022	3.819AspVal: 3.819 ± 0.034	0.867AspTrp: 0.867 ± 0.016	1.589AspTyr: 1.589 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.775GluAla: 5.775 ± 0.045	0.597GluCys: 0.597 ± 0.013	4.27GluAsp: 4.27 ± 0.037	5.605GluGlu: 5.605 ± 0.061	1.94GluPhe: 1.94 ± 0.02	3.65GluGly: 3.65 ± 0.03	1.354GluHis: 1.354 ± 0.017	3.087GluIle: 3.087 ± 0.029	3.681GluLys: 3.681 ± 0.037	5.313GluLeu: 5.313 ± 0.041	1.5GluMet: 1.5 ± 0.014	2.217GluAsn: 2.217 ± 0.021	2.794GluPro: 2.794 ± 0.034	2.495GluGln: 2.495 ± 0.023	3.783GluArg: 3.783 ± 0.037	4.275GluSer: 4.275 ± 0.037	3.395GluThr: 3.395 ± 0.03	3.415GluVal: 3.415 ± 0.03	0.89GluTrp: 0.89 ± 0.012	1.643GluTyr: 1.643 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.086PheAla: 3.086 ± 0.027	0.544PheCys: 0.544 ± 0.01	2.321PheAsp: 2.321 ± 0.022	2.124PheGlu: 2.124 ± 0.021	1.626PhePhe: 1.626 ± 0.025	2.884PheGly: 2.884 ± 0.03	0.882PheHis: 0.882 ± 0.014	1.935PheIle: 1.935 ± 0.025	1.54PheLys: 1.54 ± 0.019	3.396PheLeu: 3.396 ± 0.031	0.793PheMet: 0.793 ± 0.013	1.471PheAsn: 1.471 ± 0.016	1.915PhePro: 1.915 ± 0.02	1.41PheGln: 1.41 ± 0.018	1.891PheArg: 1.891 ± 0.021	3.055PheSer: 3.055 ± 0.027	2.115PheThr: 2.115 ± 0.022	2.362PheVal: 2.362 ± 0.025	0.644PheTrp: 0.644 ± 0.012	1.097PheTyr: 1.097 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.586GlyAla: 5.586 ± 0.035	0.852GlyCys: 0.852 ± 0.014	3.812GlyAsp: 3.812 ± 0.032	3.714GlyGlu: 3.714 ± 0.028	2.809GlyPhe: 2.809 ± 0.026	5.866GlyGly: 5.866 ± 0.066	1.717GlyHis: 1.717 ± 0.019	3.744GlyIle: 3.744 ± 0.033	3.474GlyLys: 3.474 ± 0.039	6.112GlyLeu: 6.112 ± 0.05	1.543GlyMet: 1.543 ± 0.017	2.626GlyAsn: 2.626 ± 0.028	3.319GlyPro: 3.319 ± 0.035	2.627GlyGln: 2.627 ± 0.029	4.179GlyArg: 4.179 ± 0.033	5.938GlySer: 5.938 ± 0.042	3.892GlyThr: 3.892 ± 0.04	4.301GlyVal: 4.301 ± 0.034	1.167GlyTrp: 1.167 ± 0.017	2.121GlyTyr: 2.121 ± 0.023	0.001GlyXaa: 0.001 ± 0.0
His	1.786HisAla: 1.786 ± 0.019	0.311HisCys: 0.311 ± 0.008	1.345HisAsp: 1.345 ± 0.017	1.308HisGlu: 1.308 ± 0.015	0.908HisPhe: 0.908 ± 0.015	1.73HisGly: 1.73 ± 0.021	0.889HisHis: 0.889 ± 0.017	1.269HisIle: 1.269 ± 0.016	0.931HisLys: 0.931 ± 0.014	2.191HisLeu: 2.191 ± 0.023	0.522HisMet: 0.522 ± 0.01	0.849HisAsn: 0.849 ± 0.011	1.561HisPro: 1.561 ± 0.018	1.049HisGln: 1.049 ± 0.017	1.488HisArg: 1.488 ± 0.017	1.765HisSer: 1.765 ± 0.022	1.158HisThr: 1.158 ± 0.013	1.424HisVal: 1.424 ± 0.02	0.344HisTrp: 0.344 ± 0.009	0.671HisTyr: 0.671 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.432IleAla: 4.432 ± 0.033	0.74IleCys: 0.74 ± 0.014	2.99IleAsp: 2.99 ± 0.023	3.012IleGlu: 3.012 ± 0.031	2.058IlePhe: 2.058 ± 0.02	3.349IleGly: 3.349 ± 0.033	1.255IleHis: 1.255 ± 0.017	2.728IleIle: 2.728 ± 0.029	2.365IleLys: 2.365 ± 0.024	4.621IleLeu: 4.621 ± 0.038	1.051IleMet: 1.051 ± 0.016	1.936IleAsn: 1.936 ± 0.023	3.11IlePro: 3.11 ± 0.025	2.052IleGln: 2.052 ± 0.025	2.9IleArg: 2.9 ± 0.024	4.065IleSer: 4.065 ± 0.034	2.916IleThr: 2.916 ± 0.022	3.253IleVal: 3.253 ± 0.03	0.749IleTrp: 0.749 ± 0.014	1.416IleTyr: 1.416 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.476LysAla: 4.476 ± 0.04	0.461LysCys: 0.461 ± 0.011	2.869LysAsp: 2.869 ± 0.027	3.364LysGlu: 3.364 ± 0.035	1.519LysPhe: 1.519 ± 0.019	2.983LysGly: 2.983 ± 0.027	1.095LysHis: 1.095 ± 0.015	2.335LysIle: 2.335 ± 0.022	3.384LysLys: 3.384 ± 0.045	4.259LysLeu: 4.259 ± 0.035	1.039LysMet: 1.039 ± 0.013	1.728LysAsn: 1.728 ± 0.019	2.681LysPro: 2.681 ± 0.028	1.868LysGln: 1.868 ± 0.02	3.309LysArg: 3.309 ± 0.033	3.574LysSer: 3.574 ± 0.03	2.815LysThr: 2.815 ± 0.03	2.801LysVal: 2.801 ± 0.027	0.677LysTrp: 0.677 ± 0.012	1.38LysTyr: 1.38 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	8.023LeuAla: 8.023 ± 0.044	1.173LeuCys: 1.173 ± 0.019	5.273LeuAsp: 5.273 ± 0.035	5.462LeuGlu: 5.462 ± 0.048	3.298LeuPhe: 3.298 ± 0.03	6.078LeuGly: 6.078 ± 0.047	2.144LeuHis: 2.144 ± 0.021	4.136LeuIle: 4.136 ± 0.032	4.21LeuLys: 4.21 ± 0.034	8.36LeuLeu: 8.36 ± 0.061	1.786LeuMet: 1.786 ± 0.019	3.193LeuAsn: 3.193 ± 0.029	5.46LeuPro: 5.46 ± 0.039	3.891LeuGln: 3.891 ± 0.039	5.625LeuArg: 5.625 ± 0.039	7.341LeuSer: 7.341 ± 0.042	4.722LeuThr: 4.722 ± 0.032	5.365LeuVal: 5.365 ± 0.041	1.223LeuTrp: 1.223 ± 0.016	2.256LeuTyr: 2.256 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.349MetAla: 2.349 ± 0.021	0.221MetCys: 0.221 ± 0.006	1.256MetAsp: 1.256 ± 0.016	1.315MetGlu: 1.315 ± 0.016	0.708MetPhe: 0.708 ± 0.012	1.474MetGly: 1.474 ± 0.018	0.469MetHis: 0.469 ± 0.01	0.994MetIle: 0.994 ± 0.015	1.018MetLys: 1.018 ± 0.014	1.872MetLeu: 1.872 ± 0.019	0.61MetMet: 0.61 ± 0.013	0.796MetAsn: 0.796 ± 0.013	1.32MetPro: 1.32 ± 0.018	0.866MetGln: 0.866 ± 0.013	1.279MetArg: 1.279 ± 0.016	1.842MetSer: 1.842 ± 0.02	1.296MetThr: 1.296 ± 0.016	1.306MetVal: 1.306 ± 0.015	0.264MetTrp: 0.264 ± 0.007	0.5MetTyr: 0.5 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.179AsnAla: 3.179 ± 0.029	0.438AsnCys: 0.438 ± 0.01	1.993AsnAsp: 1.993 ± 0.017	1.984AsnGlu: 1.984 ± 0.02	1.401AsnPhe: 1.401 ± 0.016	3.152AsnGly: 3.152 ± 0.042	0.864AsnHis: 0.864 ± 0.013	2.123AsnIle: 2.123 ± 0.021	1.622AsnLys: 1.622 ± 0.017	3.269AsnLeu: 3.269 ± 0.027	0.873AsnMet: 0.873 ± 0.013	1.564AsnAsn: 1.564 ± 0.022	2.377AsnPro: 2.377 ± 0.022	1.36AsnGln: 1.36 ± 0.016	1.929AsnArg: 1.929 ± 0.022	2.795AsnSer: 2.795 ± 0.027	2.106AsnThr: 2.106 ± 0.023	2.299AsnVal: 2.299 ± 0.022	0.587AsnTrp: 0.587 ± 0.012	1.077AsnTyr: 1.077 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.192ProAla: 5.192 ± 0.054	0.523ProCys: 0.523 ± 0.012	3.179ProAsp: 3.179 ± 0.031	3.729ProGlu: 3.729 ± 0.033	2.072ProPhe: 2.072 ± 0.022	3.903ProGly: 3.903 ± 0.037	1.277ProHis: 1.277 ± 0.017	2.631ProIle: 2.631 ± 0.025	2.684ProLys: 2.684 ± 0.028	4.836ProLeu: 4.836 ± 0.035	1.105ProMet: 1.105 ± 0.015	2.218ProAsn: 2.218 ± 0.022	5.154ProPro: 5.154 ± 0.075	2.471ProGln: 2.471 ± 0.031	3.321ProArg: 3.321 ± 0.031	5.838ProSer: 5.838 ± 0.051	3.716ProThr: 3.716 ± 0.031	3.499ProVal: 3.499 ± 0.031	0.721ProTrp: 0.721 ± 0.011	1.462ProTyr: 1.462 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.629GlnAla: 3.629 ± 0.028	0.424GlnCys: 0.424 ± 0.011	2.118GlnAsp: 2.118 ± 0.021	2.394GlnGlu: 2.394 ± 0.023	1.356GlnPhe: 1.356 ± 0.017	2.519GlnGly: 2.519 ± 0.024	1.078GlnHis: 1.078 ± 0.015	1.913GlnIle: 1.913 ± 0.019	1.939GlnLys: 1.939 ± 0.023	3.574GlnLeu: 3.574 ± 0.033	0.885GlnMet: 0.885 ± 0.014	1.503GlnAsn: 1.503 ± 0.02	2.616GlnPro: 2.616 ± 0.029	2.689GlnGln: 2.689 ± 0.053	2.656GlnArg: 2.656 ± 0.025	3.066GlnSer: 3.066 ± 0.025	2.203GlnThr: 2.203 ± 0.022	2.209GlnVal: 2.209 ± 0.021	0.596GlnTrp: 0.596 ± 0.011	1.149GlnTyr: 1.149 ± 0.016	0.001GlnXaa: 0.001 ± 0.0
Arg	4.667ArgAla: 4.667 ± 0.034	0.679ArgCys: 0.679 ± 0.012	3.419ArgAsp: 3.419 ± 0.034	3.732ArgGlu: 3.732 ± 0.038	2.106ArgPhe: 2.106 ± 0.02	3.726ArgGly: 3.726 ± 0.033	1.553ArgHis: 1.553 ± 0.02	2.956ArgIle: 2.956 ± 0.022	3.244ArgLys: 3.244 ± 0.029	5.504ArgLeu: 5.504 ± 0.039	1.264ArgMet: 1.264 ± 0.016	2.187ArgAsn: 2.187 ± 0.022	3.487ArgPro: 3.487 ± 0.04	2.597ArgGln: 2.597 ± 0.026	5.077ArgArg: 5.077 ± 0.055	4.648ArgSer: 4.648 ± 0.046	3.084ArgThr: 3.084 ± 0.026	3.274ArgVal: 3.274 ± 0.024	0.904ArgTrp: 0.904 ± 0.016	1.604ArgTyr: 1.604 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.882SerAla: 6.882 ± 0.041	0.838SerCys: 0.838 ± 0.015	4.279SerAsp: 4.279 ± 0.033	4.131SerGlu: 4.131 ± 0.034	3.042SerPhe: 3.042 ± 0.028	5.727SerGly: 5.727 ± 0.04	1.957SerHis: 1.957 ± 0.021	4.185SerIle: 4.185 ± 0.039	3.787SerLys: 3.787 ± 0.034	7.295SerLeu: 7.295 ± 0.034	1.729SerMet: 1.729 ± 0.018	3.047SerAsn: 3.047 ± 0.025	5.405SerPro: 5.405 ± 0.056	3.378SerGln: 3.378 ± 0.028	4.979SerArg: 4.979 ± 0.043	8.874SerSer: 8.874 ± 0.084	5.26SerThr: 5.26 ± 0.041	4.591SerVal: 4.591 ± 0.037	1.141SerTrp: 1.141 ± 0.015	2.062SerTyr: 2.062 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.255ThrAla: 5.255 ± 0.031	0.699ThrCys: 0.699 ± 0.012	2.755ThrAsp: 2.755 ± 0.024	3.063ThrGlu: 3.063 ± 0.026	2.146ThrPhe: 2.146 ± 0.02	4.172ThrGly: 4.172 ± 0.048	1.186ThrHis: 1.186 ± 0.014	3.14ThrIle: 3.14 ± 0.031	2.595ThrLys: 2.595 ± 0.025	5.032ThrLeu: 5.032 ± 0.036	1.161ThrMet: 1.161 ± 0.013	2.09ThrAsn: 2.09 ± 0.023	4.08ThrPro: 4.08 ± 0.036	1.993ThrGln: 1.993 ± 0.019	2.952ThrArg: 2.952 ± 0.025	5.032ThrSer: 5.032 ± 0.041	4.017ThrThr: 4.017 ± 0.045	3.651ThrVal: 3.651 ± 0.035	0.839ThrTrp: 0.839 ± 0.014	1.539ThrTyr: 1.539 ± 0.017	0.001ThrXaa: 0.001 ± 0.0
Val	5.458ValAla: 5.458 ± 0.034	0.762ValCys: 0.762 ± 0.014	3.746ValAsp: 3.746 ± 0.033	3.834ValGlu: 3.834 ± 0.029	2.428ValPhe: 2.428 ± 0.026	3.947ValGly: 3.947 ± 0.032	1.345ValHis: 1.345 ± 0.015	3.078ValIle: 3.078 ± 0.031	2.918ValLys: 2.918 ± 0.03	5.502ValLeu: 5.502 ± 0.041	1.309ValMet: 1.309 ± 0.017	2.288ValAsn: 2.288 ± 0.022	3.518ValPro: 3.518 ± 0.03	2.315ValGln: 2.315 ± 0.021	3.292ValArg: 3.292 ± 0.027	4.628ValSer: 4.628 ± 0.032	3.5ValThr: 3.5 ± 0.03	4.291ValVal: 4.291 ± 0.039	0.841ValTrp: 0.841 ± 0.015	1.667ValTyr: 1.667 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.198TrpAla: 1.198 ± 0.018	0.19TrpCys: 0.19 ± 0.006	0.944TrpAsp: 0.944 ± 0.016	0.857TrpGlu: 0.857 ± 0.013	0.548TrpPhe: 0.548 ± 0.012	0.941TrpGly: 0.941 ± 0.015	0.374TrpHis: 0.374 ± 0.009	0.767TrpIle: 0.767 ± 0.013	0.792TrpLys: 0.792 ± 0.014	1.341TrpLeu: 1.341 ± 0.017	0.364TrpMet: 0.364 ± 0.009	0.636TrpAsn: 0.636 ± 0.012	0.621TrpPro: 0.621 ± 0.011	0.591TrpGln: 0.591 ± 0.012	0.942TrpArg: 0.942 ± 0.013	1.041TrpSer: 1.041 ± 0.014	0.881TrpThr: 0.881 ± 0.015	0.86TrpVal: 0.86 ± 0.014	0.283TrpTrp: 0.283 ± 0.007	0.414TrpTyr: 0.414 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.127TyrAla: 2.127 ± 0.022	0.405TyrCys: 0.405 ± 0.01	1.648TyrAsp: 1.648 ± 0.019	1.558TyrGlu: 1.558 ± 0.018	1.17TyrPhe: 1.17 ± 0.016	2.111TyrGly: 2.111 ± 0.023	0.733TyrHis: 0.733 ± 0.011	1.405TyrIle: 1.405 ± 0.02	1.109TyrLys: 1.109 ± 0.015	2.544TyrLeu: 2.544 ± 0.025	0.619TyrMet: 0.619 ± 0.012	1.113TyrAsn: 1.113 ± 0.016	1.449TyrPro: 1.449 ± 0.02	1.058TyrGln: 1.058 ± 0.014	1.549TyrArg: 1.549 ± 0.018	2.011TyrSer: 2.011 ± 0.024	1.513TyrThr: 1.513 ± 0.017	1.608TyrVal: 1.608 ± 0.018	0.446TyrTrp: 0.446 ± 0.01	0.891TyrTyr: 0.891 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.025XaaXaa: 0.025 ± 0.01

Statistics based on 10471 proteins (5304629 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---