Amino acid dipepetide frequency for Corynebacterium falsenii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.419AlaAla: 15.419 ± 0.238	0.876AlaCys: 0.876 ± 0.039	7.407AlaAsp: 7.407 ± 0.123	7.955AlaGlu: 7.955 ± 0.134	3.338AlaPhe: 3.338 ± 0.065	10.395AlaGly: 10.395 ± 0.157	2.388AlaHis: 2.388 ± 0.065	5.21AlaIle: 5.21 ± 0.101	3.879AlaLys: 3.879 ± 0.095	10.621AlaLeu: 10.621 ± 0.126	2.727AlaMet: 2.727 ± 0.066	2.866AlaAsn: 2.866 ± 0.068	5.06AlaPro: 5.06 ± 0.133	4.35AlaGln: 4.35 ± 0.089	6.829AlaArg: 6.829 ± 0.111	6.411AlaSer: 6.411 ± 0.103	7.332AlaThr: 7.332 ± 0.104	9.263AlaVal: 9.263 ± 0.135	1.481AlaTrp: 1.481 ± 0.057	2.233AlaTyr: 2.233 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	0.813CysAla: 0.813 ± 0.037	0.092CysCys: 0.092 ± 0.011	0.443CysAsp: 0.443 ± 0.025	0.363CysGlu: 0.363 ± 0.025	0.219CysPhe: 0.219 ± 0.016	0.737CysGly: 0.737 ± 0.037	0.156CysHis: 0.156 ± 0.014	0.322CysIle: 0.322 ± 0.019	0.13CysLys: 0.13 ± 0.014	0.546CysLeu: 0.546 ± 0.028	0.132CysMet: 0.132 ± 0.014	0.188CysAsn: 0.188 ± 0.017	0.447CysPro: 0.447 ± 0.028	0.178CysGln: 0.178 ± 0.015	0.406CysArg: 0.406 ± 0.027	0.529CysSer: 0.529 ± 0.03	0.439CysThr: 0.439 ± 0.025	0.589CysVal: 0.589 ± 0.031	0.088CysTrp: 0.088 ± 0.013	0.131CysTyr: 0.131 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	7.291AspAla: 7.291 ± 0.114	0.374AspCys: 0.374 ± 0.023	3.89AspAsp: 3.89 ± 0.087	4.258AspGlu: 4.258 ± 0.091	1.95AspPhe: 1.95 ± 0.055	5.292AspGly: 5.292 ± 0.091	1.398AspHis: 1.398 ± 0.049	3.025AspIle: 3.025 ± 0.065	2.322AspLys: 2.322 ± 0.071	5.555AspLeu: 5.555 ± 0.099	1.287AspMet: 1.287 ± 0.042	2.131AspAsn: 2.131 ± 0.064	3.84AspPro: 3.84 ± 0.085	2.088AspGln: 2.088 ± 0.053	3.816AspArg: 3.816 ± 0.083	3.667AspSer: 3.667 ± 0.078	3.245AspThr: 3.245 ± 0.069	4.987AspVal: 4.987 ± 0.103	0.816AspTrp: 0.816 ± 0.035	1.545AspTyr: 1.545 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	6.761GluAla: 6.761 ± 0.116	0.351GluCys: 0.351 ± 0.024	3.8GluAsp: 3.8 ± 0.079	3.995GluGlu: 3.995 ± 0.097	2.07GluPhe: 2.07 ± 0.061	4.443GluGly: 4.443 ± 0.089	1.673GluHis: 1.673 ± 0.054	2.979GluIle: 2.979 ± 0.074	2.468GluLys: 2.468 ± 0.068	6.365GluLeu: 6.365 ± 0.107	1.291GluMet: 1.291 ± 0.046	1.681GluAsn: 1.681 ± 0.054	2.963GluPro: 2.963 ± 0.074	2.83GluGln: 2.83 ± 0.066	4.082GluArg: 4.082 ± 0.081	3.269GluSer: 3.269 ± 0.07	2.904GluThr: 2.904 ± 0.07	4.616GluVal: 4.616 ± 0.093	0.859GluTrp: 0.859 ± 0.038	1.309GluTyr: 1.309 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.629PheAla: 3.629 ± 0.068	0.258PheCys: 0.258 ± 0.018	2.194PheAsp: 2.194 ± 0.06	1.549PheGlu: 1.549 ± 0.055	1.243PhePhe: 1.243 ± 0.049	3.258PheGly: 3.258 ± 0.074	0.718PheHis: 0.718 ± 0.029	1.56PheIle: 1.56 ± 0.051	0.749PheLys: 0.749 ± 0.035	2.744PheLeu: 2.744 ± 0.066	0.678PheMet: 0.678 ± 0.033	1.024PheAsn: 1.024 ± 0.039	1.426PhePro: 1.426 ± 0.038	0.879PheGln: 0.879 ± 0.034	1.689PheArg: 1.689 ± 0.046	2.114PheSer: 2.114 ± 0.054	2.158PheThr: 2.158 ± 0.056	2.558PheVal: 2.558 ± 0.063	0.413PheTrp: 0.413 ± 0.026	0.748PheTyr: 0.748 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.198GlyAla: 9.198 ± 0.151	0.652GlyCys: 0.652 ± 0.031	4.833GlyAsp: 4.833 ± 0.084	5.069GlyGlu: 5.069 ± 0.091	3.038GlyPhe: 3.038 ± 0.065	7.39GlyGly: 7.39 ± 0.149	2.075GlyHis: 2.075 ± 0.053	4.35GlyIle: 4.35 ± 0.091	3.171GlyLys: 3.171 ± 0.066	7.921GlyLeu: 7.921 ± 0.137	2.303GlyMet: 2.303 ± 0.057	2.377GlyAsn: 2.377 ± 0.063	3.465GlyPro: 3.465 ± 0.072	2.982GlyGln: 2.982 ± 0.068	5.129GlyArg: 5.129 ± 0.079	5.626GlySer: 5.626 ± 0.104	5.408GlyThr: 5.408 ± 0.082	7.259GlyVal: 7.259 ± 0.113	1.417GlyTrp: 1.417 ± 0.05	2.126GlyTyr: 2.126 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	2.397HisAla: 2.397 ± 0.058	0.194HisCys: 0.194 ± 0.016	1.322HisAsp: 1.322 ± 0.045	1.237HisGlu: 1.237 ± 0.048	0.626HisPhe: 0.626 ± 0.03	2.076HisGly: 2.076 ± 0.058	0.684HisHis: 0.684 ± 0.035	1.076HisIle: 1.076 ± 0.038	0.573HisLys: 0.573 ± 0.027	1.91HisLeu: 1.91 ± 0.046	0.462HisMet: 0.462 ± 0.026	0.65HisAsn: 0.65 ± 0.029	1.561HisPro: 1.561 ± 0.046	0.69HisGln: 0.69 ± 0.03	1.609HisArg: 1.609 ± 0.046	1.365HisSer: 1.365 ± 0.048	1.406HisThr: 1.406 ± 0.045	1.662HisVal: 1.662 ± 0.046	0.295HisTrp: 0.295 ± 0.02	0.526HisTyr: 0.526 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.211IleAla: 6.211 ± 0.112	0.359IleCys: 0.359 ± 0.023	3.329IleAsp: 3.329 ± 0.076	2.743IleGlu: 2.743 ± 0.063	1.518IlePhe: 1.518 ± 0.055	4.318IleGly: 4.318 ± 0.082	0.972IleHis: 0.972 ± 0.039	2.562IleIle: 2.562 ± 0.06	1.301IleLys: 1.301 ± 0.043	4.038IleLeu: 4.038 ± 0.086	1.012IleMet: 1.012 ± 0.043	1.654IleAsn: 1.654 ± 0.045	2.684IlePro: 2.684 ± 0.07	1.211IleGln: 1.211 ± 0.039	2.779IleArg: 2.779 ± 0.061	2.924IleSer: 2.924 ± 0.064	3.169IleThr: 3.169 ± 0.063	4.292IleVal: 4.292 ± 0.09	0.482IleTrp: 0.482 ± 0.026	0.969IleTyr: 0.969 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.738LysAla: 3.738 ± 0.087	0.131LysCys: 0.131 ± 0.014	2.29LysAsp: 2.29 ± 0.064	1.995LysGlu: 1.995 ± 0.06	0.891LysPhe: 0.891 ± 0.031	2.474LysGly: 2.474 ± 0.069	0.676LysHis: 0.676 ± 0.027	1.666LysIle: 1.666 ± 0.051	1.935LysLys: 1.935 ± 0.063	3.054LysLeu: 3.054 ± 0.068	0.777LysMet: 0.777 ± 0.033	1.176LysAsn: 1.176 ± 0.047	1.781LysPro: 1.781 ± 0.056	1.196LysGln: 1.196 ± 0.045	2.09LysArg: 2.09 ± 0.055	1.788LysSer: 1.788 ± 0.056	1.976LysThr: 1.976 ± 0.054	2.577LysVal: 2.577 ± 0.069	0.426LysTrp: 0.426 ± 0.024	0.705LysTyr: 0.705 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	10.987LeuAla: 10.987 ± 0.143	0.705LeuCys: 0.705 ± 0.035	6.02LeuAsp: 6.02 ± 0.1	4.807LeuGlu: 4.807 ± 0.094	2.748LeuPhe: 2.748 ± 0.077	7.957LeuGly: 7.957 ± 0.118	1.942LeuHis: 1.942 ± 0.047	4.515LeuIle: 4.515 ± 0.102	2.716LeuLys: 2.716 ± 0.065	8.071LeuLeu: 8.071 ± 0.13	1.956LeuMet: 1.956 ± 0.053	2.592LeuAsn: 2.592 ± 0.058	5.038LeuPro: 5.038 ± 0.086	2.651LeuGln: 2.651 ± 0.058	6.098LeuArg: 6.098 ± 0.1	5.608LeuSer: 5.608 ± 0.088	5.718LeuThr: 5.718 ± 0.087	7.529LeuVal: 7.529 ± 0.106	1.192LeuTrp: 1.192 ± 0.047	1.715LeuTyr: 1.715 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.689MetAla: 2.689 ± 0.06	0.15MetCys: 0.15 ± 0.012	1.285MetAsp: 1.285 ± 0.045	1.166MetGlu: 1.166 ± 0.04	0.704MetPhe: 0.704 ± 0.032	1.856MetGly: 1.856 ± 0.055	0.41MetHis: 0.41 ± 0.026	1.187MetIle: 1.187 ± 0.039	0.713MetLys: 0.713 ± 0.027	2.162MetLeu: 2.162 ± 0.052	0.549MetMet: 0.549 ± 0.028	0.769MetAsn: 0.769 ± 0.029	1.214MetPro: 1.214 ± 0.044	0.706MetGln: 0.706 ± 0.029	1.427MetArg: 1.427 ± 0.045	1.745MetSer: 1.745 ± 0.046	1.708MetThr: 1.708 ± 0.049	1.781MetVal: 1.781 ± 0.049	0.298MetTrp: 0.298 ± 0.02	0.402MetTyr: 0.402 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.121AsnAla: 3.121 ± 0.064	0.167AsnCys: 0.167 ± 0.015	1.735AsnAsp: 1.735 ± 0.054	1.525AsnGlu: 1.525 ± 0.048	0.884AsnPhe: 0.884 ± 0.036	2.513AsnGly: 2.513 ± 0.066	0.66AsnHis: 0.66 ± 0.029	1.319AsnIle: 1.319 ± 0.039	1.026AsnLys: 1.026 ± 0.041	2.603AsnLeu: 2.603 ± 0.057	0.656AsnMet: 0.656 ± 0.032	1.09AsnAsn: 1.09 ± 0.052	2.245AsnPro: 2.245 ± 0.057	1.022AsnGln: 1.022 ± 0.043	1.836AsnArg: 1.836 ± 0.06	1.848AsnSer: 1.848 ± 0.064	1.78AsnThr: 1.78 ± 0.054	2.239AsnVal: 2.239 ± 0.059	0.382AsnTrp: 0.382 ± 0.022	0.773AsnTyr: 0.773 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	5.778ProAla: 5.778 ± 0.112	0.258ProCys: 0.258 ± 0.023	3.5ProAsp: 3.5 ± 0.067	4.289ProGlu: 4.289 ± 0.076	1.573ProPhe: 1.573 ± 0.047	4.838ProGly: 4.838 ± 0.11	1.231ProHis: 1.231 ± 0.043	2.139ProIle: 2.139 ± 0.051	1.687ProLys: 1.687 ± 0.055	4.253ProLeu: 4.253 ± 0.082	1.062ProMet: 1.062 ± 0.039	1.537ProAsn: 1.537 ± 0.055	2.038ProPro: 2.038 ± 0.066	2.031ProGln: 2.031 ± 0.051	2.906ProArg: 2.906 ± 0.067	3.234ProSer: 3.234 ± 0.068	3.524ProThr: 3.524 ± 0.072	4.379ProVal: 4.379 ± 0.075	0.717ProTrp: 0.717 ± 0.035	1.023ProTyr: 1.023 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	4.039GlnAla: 4.039 ± 0.086	0.212GlnCys: 0.212 ± 0.017	1.735GlnAsp: 1.735 ± 0.05	1.93GlnGlu: 1.93 ± 0.061	0.988GlnPhe: 0.988 ± 0.039	2.51GlnGly: 2.51 ± 0.057	0.825GlnHis: 0.825 ± 0.035	1.704GlnIle: 1.704 ± 0.049	1.171GlnLys: 1.171 ± 0.045	3.535GlnLeu: 3.535 ± 0.077	0.78GlnMet: 0.78 ± 0.031	0.92GlnAsn: 0.92 ± 0.038	2.03GlnPro: 2.03 ± 0.059	1.763GlnGln: 1.763 ± 0.068	2.808GlnArg: 2.808 ± 0.076	1.748GlnSer: 1.748 ± 0.051	1.585GlnThr: 1.585 ± 0.047	2.64GlnVal: 2.64 ± 0.062	0.652GlnTrp: 0.652 ± 0.03	0.649GlnTyr: 0.649 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	6.498ArgAla: 6.498 ± 0.097	0.391ArgCys: 0.391 ± 0.024	3.689ArgAsp: 3.689 ± 0.085	4.079ArgGlu: 4.079 ± 0.086	2.075ArgPhe: 2.075 ± 0.049	4.76ArgGly: 4.76 ± 0.093	1.393ArgHis: 1.393 ± 0.047	3.117ArgIle: 3.117 ± 0.067	2.315ArgLys: 2.315 ± 0.055	5.467ArgLeu: 5.467 ± 0.085	1.803ArgMet: 1.803 ± 0.047	1.861ArgAsn: 1.861 ± 0.059	3.183ArgPro: 3.183 ± 0.066	2.287ArgGln: 2.287 ± 0.059	5.166ArgArg: 5.166 ± 0.125	3.734ArgSer: 3.734 ± 0.073	3.883ArgThr: 3.883 ± 0.085	4.731ArgVal: 4.731 ± 0.084	1.032ArgTrp: 1.032 ± 0.038	1.516ArgTyr: 1.516 ± 0.046	0.0ArgXaa: 0.0 ± 0.0
Ser	7.083SerAla: 7.083 ± 0.111	0.347SerCys: 0.347 ± 0.025	3.698SerAsp: 3.698 ± 0.068	3.432SerGlu: 3.432 ± 0.078	1.839SerPhe: 1.839 ± 0.055	5.839SerGly: 5.839 ± 0.083	1.293SerHis: 1.293 ± 0.042	2.672SerIle: 2.672 ± 0.064	1.869SerLys: 1.869 ± 0.056	5.142SerLeu: 5.142 ± 0.09	1.509SerMet: 1.509 ± 0.038	1.674SerAsn: 1.674 ± 0.049	3.219SerPro: 3.219 ± 0.061	1.979SerGln: 1.979 ± 0.055	3.639SerArg: 3.639 ± 0.081	4.371SerSer: 4.371 ± 0.11	4.221SerThr: 4.221 ± 0.078	4.559SerVal: 4.559 ± 0.073	0.896SerTrp: 0.896 ± 0.04	1.258SerTyr: 1.258 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	6.93ThrAla: 6.93 ± 0.121	0.461ThrCys: 0.461 ± 0.03	3.874ThrAsp: 3.874 ± 0.08	3.235ThrGlu: 3.235 ± 0.069	1.956ThrPhe: 1.956 ± 0.062	5.668ThrGly: 5.668 ± 0.086	1.337ThrHis: 1.337 ± 0.042	3.182ThrIle: 3.182 ± 0.067	1.891ThrLys: 1.891 ± 0.054	5.376ThrLeu: 5.376 ± 0.088	1.363ThrMet: 1.363 ± 0.045	1.815ThrAsn: 1.815 ± 0.056	3.86ThrPro: 3.86 ± 0.075	1.852ThrGln: 1.852 ± 0.051	3.282ThrArg: 3.282 ± 0.073	3.718ThrSer: 3.718 ± 0.077	4.48ThrThr: 4.48 ± 0.099	5.715ThrVal: 5.715 ± 0.085	0.904ThrTrp: 0.904 ± 0.035	1.314ThrTyr: 1.314 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	9.633ValAla: 9.633 ± 0.136	0.686ValCys: 0.686 ± 0.031	5.707ValAsp: 5.707 ± 0.103	5.16ValGlu: 5.16 ± 0.099	2.561ValPhe: 2.561 ± 0.065	6.548ValGly: 6.548 ± 0.105	1.799ValHis: 1.799 ± 0.051	4.314ValIle: 4.314 ± 0.08	2.315ValLys: 2.315 ± 0.069	7.587ValLeu: 7.587 ± 0.128	1.784ValMet: 1.784 ± 0.055	2.285ValAsn: 2.285 ± 0.066	4.099ValPro: 4.099 ± 0.083	2.269ValGln: 2.269 ± 0.057	4.891ValArg: 4.891 ± 0.091	4.642ValSer: 4.642 ± 0.085	5.253ValThr: 5.253 ± 0.102	7.666ValVal: 7.666 ± 0.117	1.07ValTrp: 1.07 ± 0.041	1.513ValTyr: 1.513 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	1.534TrpAla: 1.534 ± 0.049	0.111TrpCys: 0.111 ± 0.013	0.762TrpAsp: 0.762 ± 0.034	0.761TrpGlu: 0.761 ± 0.031	0.608TrpPhe: 0.608 ± 0.034	0.959TrpGly: 0.959 ± 0.038	0.286TrpHis: 0.286 ± 0.021	0.708TrpIle: 0.708 ± 0.035	0.518TrpLys: 0.518 ± 0.029	1.457TrpLeu: 1.457 ± 0.053	0.383TrpMet: 0.383 ± 0.023	0.478TrpAsn: 0.478 ± 0.023	0.642TrpPro: 0.642 ± 0.029	0.522TrpGln: 0.522 ± 0.027	0.993TrpArg: 0.993 ± 0.036	0.841TrpSer: 0.841 ± 0.04	0.752TrpThr: 0.752 ± 0.037	1.156TrpVal: 1.156 ± 0.049	0.358TrpTrp: 0.358 ± 0.028	0.282TrpTyr: 0.282 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.293TyrAla: 2.293 ± 0.06	0.175TyrCys: 0.175 ± 0.016	1.266TyrAsp: 1.266 ± 0.041	1.162TyrGlu: 1.162 ± 0.044	0.761TyrPhe: 0.761 ± 0.033	1.954TyrGly: 1.954 ± 0.05	0.407TyrHis: 0.407 ± 0.023	0.92TyrIle: 0.92 ± 0.039	0.594TyrLys: 0.594 ± 0.031	2.158TyrLeu: 2.158 ± 0.059	0.405TyrMet: 0.405 ± 0.023	0.652TyrAsn: 0.652 ± 0.029	1.198TyrPro: 1.198 ± 0.035	0.737TyrGln: 0.737 ± 0.027	1.505TyrArg: 1.505 ± 0.044	1.358TyrSer: 1.358 ± 0.042	1.273TyrThr: 1.273 ± 0.041	1.584TyrVal: 1.584 ± 0.05	0.335TyrTrp: 0.335 ± 0.023	0.467TyrTyr: 0.467 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2134 proteins (748884 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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