Amino acid dipepetide frequency for Croceitalea dokdonensis DOKDO 023

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.316AlaAla: 5.316 ± 0.1	0.621AlaCys: 0.621 ± 0.023	3.71AlaAsp: 3.71 ± 0.068	4.215AlaGlu: 4.215 ± 0.066	3.571AlaPhe: 3.571 ± 0.061	4.559AlaGly: 4.559 ± 0.076	1.353AlaHis: 1.353 ± 0.038	5.498AlaIle: 5.498 ± 0.073	5.207AlaLys: 5.207 ± 0.084	7.18AlaLeu: 7.18 ± 0.105	1.889AlaMet: 1.889 ± 0.047	3.867AlaAsn: 3.867 ± 0.07	2.331AlaPro: 2.331 ± 0.059	2.866AlaGln: 2.866 ± 0.052	2.312AlaArg: 2.312 ± 0.049	4.314AlaSer: 4.314 ± 0.057	4.143AlaThr: 4.143 ± 0.081	4.744AlaVal: 4.744 ± 0.075	0.721AlaTrp: 0.721 ± 0.027	2.782AlaTyr: 2.782 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.488CysAla: 0.488 ± 0.02	0.114CysCys: 0.114 ± 0.01	0.428CysAsp: 0.428 ± 0.022	0.446CysGlu: 0.446 ± 0.02	0.431CysPhe: 0.431 ± 0.019	0.601CysGly: 0.601 ± 0.024	0.196CysHis: 0.196 ± 0.014	0.513CysIle: 0.513 ± 0.021	0.449CysLys: 0.449 ± 0.018	0.722CysLeu: 0.722 ± 0.026	0.156CysMet: 0.156 ± 0.013	0.375CysAsn: 0.375 ± 0.02	0.338CysPro: 0.338 ± 0.02	0.247CysGln: 0.247 ± 0.014	0.212CysArg: 0.212 ± 0.014	0.543CysSer: 0.543 ± 0.025	0.496CysThr: 0.496 ± 0.024	0.407CysVal: 0.407 ± 0.02	0.071CysTrp: 0.071 ± 0.008	0.303CysTyr: 0.303 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.271AspAla: 4.271 ± 0.07	0.409AspCys: 0.409 ± 0.024	2.911AspAsp: 2.911 ± 0.089	3.217AspGlu: 3.217 ± 0.053	3.617AspPhe: 3.617 ± 0.06	4.545AspGly: 4.545 ± 0.148	1.001AspHis: 1.001 ± 0.029	4.329AspIle: 4.329 ± 0.064	3.511AspLys: 3.511 ± 0.07	4.971AspLeu: 4.971 ± 0.068	1.257AspMet: 1.257 ± 0.035	2.956AspAsn: 2.956 ± 0.061	1.763AspPro: 1.763 ± 0.044	1.644AspGln: 1.644 ± 0.043	2.169AspArg: 2.169 ± 0.045	3.187AspSer: 3.187 ± 0.07	3.198AspThr: 3.198 ± 0.09	3.744AspVal: 3.744 ± 0.056	0.771AspTrp: 0.771 ± 0.027	2.568AspTyr: 2.568 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.621GluAla: 4.621 ± 0.071	0.296GluCys: 0.296 ± 0.016	3.558GluAsp: 3.558 ± 0.061	4.523GluGlu: 4.523 ± 0.073	2.758GluPhe: 2.758 ± 0.05	3.821GluGly: 3.821 ± 0.07	1.256GluHis: 1.256 ± 0.036	4.523GluIle: 4.523 ± 0.072	4.959GluLys: 4.959 ± 0.085	6.107GluLeu: 6.107 ± 0.088	1.563GluMet: 1.563 ± 0.037	3.878GluAsn: 3.878 ± 0.062	1.832GluPro: 1.832 ± 0.04	2.494GluGln: 2.494 ± 0.053	2.96GluArg: 2.96 ± 0.051	2.988GluSer: 2.988 ± 0.053	3.532GluThr: 3.532 ± 0.055	4.538GluVal: 4.538 ± 0.065	0.626GluTrp: 0.626 ± 0.025	2.13GluTyr: 2.13 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.342PheAla: 3.342 ± 0.057	0.434PheCys: 0.434 ± 0.02	3.221PheAsp: 3.221 ± 0.053	3.37PheGlu: 3.37 ± 0.057	2.943PhePhe: 2.943 ± 0.062	3.966PheGly: 3.966 ± 0.063	0.841PheHis: 0.841 ± 0.026	3.267PheIle: 3.267 ± 0.059	3.57PheLys: 3.57 ± 0.063	5.118PheLeu: 5.118 ± 0.074	1.276PheMet: 1.276 ± 0.038	3.031PheAsn: 3.031 ± 0.068	1.728PhePro: 1.728 ± 0.038	1.712PheGln: 1.712 ± 0.044	1.821PheArg: 1.821 ± 0.04	3.686PheSer: 3.686 ± 0.058	3.098PheThr: 3.098 ± 0.047	3.095PheVal: 3.095 ± 0.051	0.618PheTrp: 0.618 ± 0.027	2.11PheTyr: 2.11 ± 0.045	0.0PheXaa: 0.0 ± 0.0
Gly	4.81GlyAla: 4.81 ± 0.077	0.677GlyCys: 0.677 ± 0.038	3.761GlyAsp: 3.761 ± 0.076	3.81GlyGlu: 3.81 ± 0.061	3.986GlyPhe: 3.986 ± 0.057	4.845GlyGly: 4.845 ± 0.096	1.352GlyHis: 1.352 ± 0.037	5.415GlyIle: 5.415 ± 0.08	4.925GlyLys: 4.925 ± 0.077	6.581GlyLeu: 6.581 ± 0.084	1.849GlyMet: 1.849 ± 0.045	3.866GlyAsn: 3.866 ± 0.071	1.588GlyPro: 1.588 ± 0.039	2.459GlyGln: 2.459 ± 0.054	2.469GlyArg: 2.469 ± 0.049	3.983GlySer: 3.983 ± 0.064	4.504GlyThr: 4.504 ± 0.114	4.54GlyVal: 4.54 ± 0.061	0.867GlyTrp: 0.867 ± 0.034	2.925GlyTyr: 2.925 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	1.127HisAla: 1.127 ± 0.033	0.2HisCys: 0.2 ± 0.013	0.846HisAsp: 0.846 ± 0.031	0.973HisGlu: 0.973 ± 0.029	1.162HisPhe: 1.162 ± 0.032	1.208HisGly: 1.208 ± 0.039	0.553HisHis: 0.553 ± 0.024	1.439HisIle: 1.439 ± 0.037	1.221HisLys: 1.221 ± 0.037	2.006HisLeu: 2.006 ± 0.047	0.404HisMet: 0.404 ± 0.02	0.859HisAsn: 0.859 ± 0.027	1.022HisPro: 1.022 ± 0.028	0.953HisGln: 0.953 ± 0.031	0.799HisArg: 0.799 ± 0.026	1.008HisSer: 1.008 ± 0.029	1.021HisThr: 1.021 ± 0.031	1.058HisVal: 1.058 ± 0.034	0.271HisTrp: 0.271 ± 0.016	0.842HisTyr: 0.842 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.642IleAla: 5.642 ± 0.082	0.573IleCys: 0.573 ± 0.022	4.111IleAsp: 4.111 ± 0.06	4.236IleGlu: 4.236 ± 0.065	3.241IlePhe: 3.241 ± 0.053	4.969IleGly: 4.969 ± 0.074	1.287IleHis: 1.287 ± 0.035	4.609IleIle: 4.609 ± 0.077	4.737IleLys: 4.737 ± 0.077	6.378IleLeu: 6.378 ± 0.078	1.24IleMet: 1.24 ± 0.036	3.761IleAsn: 3.761 ± 0.066	3.105IlePro: 3.105 ± 0.056	2.426IleGln: 2.426 ± 0.052	2.688IleArg: 2.688 ± 0.051	4.805IleSer: 4.805 ± 0.061	4.502IleThr: 4.502 ± 0.091	4.091IleVal: 4.091 ± 0.068	0.762IleTrp: 0.762 ± 0.031	2.358IleTyr: 2.358 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	5.179LysAla: 5.179 ± 0.091	0.282LysCys: 0.282 ± 0.015	4.099LysAsp: 4.099 ± 0.067	5.668LysGlu: 5.668 ± 0.096	2.395LysPhe: 2.395 ± 0.052	4.606LysGly: 4.606 ± 0.069	1.303LysHis: 1.303 ± 0.038	4.817LysIle: 4.817 ± 0.075	6.35LysLys: 6.35 ± 0.106	5.918LysLeu: 5.918 ± 0.091	1.819LysMet: 1.819 ± 0.041	4.417LysAsn: 4.417 ± 0.072	2.324LysPro: 2.324 ± 0.055	2.674LysGln: 2.674 ± 0.055	3.126LysArg: 3.126 ± 0.063	3.918LysSer: 3.918 ± 0.066	4.369LysThr: 4.369 ± 0.072	4.535LysVal: 4.535 ± 0.075	0.723LysTrp: 0.723 ± 0.03	2.418LysTyr: 2.418 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	7.074LeuAla: 7.074 ± 0.104	0.786LeuCys: 0.786 ± 0.027	5.565LeuAsp: 5.565 ± 0.089	6.31LeuGlu: 6.31 ± 0.079	5.08LeuPhe: 5.08 ± 0.08	6.918LeuGly: 6.918 ± 0.09	1.676LeuHis: 1.676 ± 0.044	5.797LeuIle: 5.797 ± 0.073	7.104LeuLys: 7.104 ± 0.105	9.565LeuLeu: 9.565 ± 0.121	2.244LeuMet: 2.244 ± 0.051	5.27LeuAsn: 5.27 ± 0.084	4.038LeuPro: 4.038 ± 0.051	3.711LeuGln: 3.711 ± 0.068	3.807LeuArg: 3.807 ± 0.067	6.219LeuSer: 6.219 ± 0.074	5.165LeuThr: 5.165 ± 0.068	6.303LeuVal: 6.303 ± 0.087	0.992LeuTrp: 0.992 ± 0.03	3.11LeuTyr: 3.11 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.011MetAla: 2.011 ± 0.043	0.14MetCys: 0.14 ± 0.012	1.464MetAsp: 1.464 ± 0.033	1.738MetGlu: 1.738 ± 0.042	0.92MetPhe: 0.92 ± 0.042	1.76MetGly: 1.76 ± 0.044	0.451MetHis: 0.451 ± 0.019	1.301MetIle: 1.301 ± 0.034	1.812MetLys: 1.812 ± 0.039	2.106MetLeu: 2.106 ± 0.044	0.612MetMet: 0.612 ± 0.028	1.159MetAsn: 1.159 ± 0.031	0.958MetPro: 0.958 ± 0.03	0.87MetGln: 0.87 ± 0.029	0.972MetArg: 0.972 ± 0.029	1.231MetSer: 1.231 ± 0.044	1.226MetThr: 1.226 ± 0.035	1.817MetVal: 1.817 ± 0.039	0.169MetTrp: 0.169 ± 0.013	0.665MetTyr: 0.665 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.968AsnAla: 3.968 ± 0.066	0.444AsnCys: 0.444 ± 0.025	2.993AsnAsp: 2.993 ± 0.076	3.204AsnGlu: 3.204 ± 0.051	2.818AsnPhe: 2.818 ± 0.058	4.251AsnGly: 4.251 ± 0.078	1.07AsnHis: 1.07 ± 0.031	3.85AsnIle: 3.85 ± 0.062	3.213AsnLys: 3.213 ± 0.059	5.067AsnLeu: 5.067 ± 0.088	1.219AsnMet: 1.219 ± 0.033	3.03AsnAsn: 3.03 ± 0.071	2.818AsnPro: 2.818 ± 0.056	2.341AsnGln: 2.341 ± 0.047	2.334AsnArg: 2.334 ± 0.057	3.137AsnSer: 3.137 ± 0.056	3.708AsnThr: 3.708 ± 0.082	3.181AsnVal: 3.181 ± 0.066	0.713AsnTrp: 0.713 ± 0.029	2.358AsnTyr: 2.358 ± 0.049	0.0AsnXaa: 0.0 ± 0.0
Pro	2.109ProAla: 2.109 ± 0.049	0.222ProCys: 0.222 ± 0.014	2.263ProAsp: 2.263 ± 0.062	2.889ProGlu: 2.889 ± 0.047	2.05ProPhe: 2.05 ± 0.044	2.101ProGly: 2.101 ± 0.051	0.649ProHis: 0.649 ± 0.022	2.705ProIle: 2.705 ± 0.047	2.899ProLys: 2.899 ± 0.057	3.448ProLeu: 3.448 ± 0.052	0.933ProMet: 0.933 ± 0.03	2.457ProAsn: 2.457 ± 0.061	1.053ProPro: 1.053 ± 0.04	1.257ProGln: 1.257 ± 0.028	1.12ProArg: 1.12 ± 0.034	2.238ProSer: 2.238 ± 0.049	2.204ProThr: 2.204 ± 0.049	2.345ProVal: 2.345 ± 0.051	0.415ProTrp: 0.415 ± 0.02	1.502ProTyr: 1.502 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	2.343GlnAla: 2.343 ± 0.044	0.191GlnCys: 0.191 ± 0.012	1.848GlnAsp: 1.848 ± 0.043	2.66GlnGlu: 2.66 ± 0.045	1.77GlnPhe: 1.77 ± 0.044	2.335GlnGly: 2.335 ± 0.046	0.759GlnHis: 0.759 ± 0.027	2.522GlnIle: 2.522 ± 0.049	2.934GlnLys: 2.934 ± 0.061	4.297GlnLeu: 4.297 ± 0.068	0.888GlnMet: 0.888 ± 0.031	2.154GlnAsn: 2.154 ± 0.053	1.329GlnPro: 1.329 ± 0.042	1.857GlnGln: 1.857 ± 0.052	1.711GlnArg: 1.711 ± 0.043	1.803GlnSer: 1.803 ± 0.042	2.002GlnThr: 2.002 ± 0.043	2.23GlnVal: 2.23 ± 0.043	0.498GlnTrp: 0.498 ± 0.02	1.306GlnTyr: 1.306 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.45ArgAla: 2.45 ± 0.052	0.212ArgCys: 0.212 ± 0.015	1.985ArgAsp: 1.985 ± 0.046	2.348ArgGlu: 2.348 ± 0.056	2.306ArgPhe: 2.306 ± 0.055	2.225ArgGly: 2.225 ± 0.049	0.694ArgHis: 0.694 ± 0.026	3.004ArgIle: 3.004 ± 0.055	2.863ArgLys: 2.863 ± 0.061	3.968ArgLeu: 3.968 ± 0.072	1.033ArgMet: 1.033 ± 0.029	2.155ArgAsn: 2.155 ± 0.05	1.471ArgPro: 1.471 ± 0.035	1.381ArgGln: 1.381 ± 0.038	1.569ArgArg: 1.569 ± 0.04	2.095ArgSer: 2.095 ± 0.05	2.209ArgThr: 2.209 ± 0.045	2.286ArgVal: 2.286 ± 0.041	0.487ArgTrp: 0.487 ± 0.018	1.803ArgTyr: 1.803 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	3.766SerAla: 3.766 ± 0.07	0.636SerCys: 0.636 ± 0.028	3.0SerAsp: 3.0 ± 0.061	3.361SerGlu: 3.361 ± 0.063	3.577SerPhe: 3.577 ± 0.057	4.534SerGly: 4.534 ± 0.079	1.019SerHis: 1.019 ± 0.031	4.409SerIle: 4.409 ± 0.069	4.23SerLys: 4.23 ± 0.068	5.982SerLeu: 5.982 ± 0.075	1.339SerMet: 1.339 ± 0.035	3.249SerAsn: 3.249 ± 0.056	2.189SerPro: 2.189 ± 0.05	2.05SerGln: 2.05 ± 0.041	2.095SerArg: 2.095 ± 0.05	3.602SerSer: 3.602 ± 0.067	3.344SerThr: 3.344 ± 0.059	3.702SerVal: 3.702 ± 0.062	0.772SerTrp: 0.772 ± 0.032	2.47SerTyr: 2.47 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	4.388ThrAla: 4.388 ± 0.086	0.338ThrCys: 0.338 ± 0.019	3.517ThrAsp: 3.517 ± 0.118	3.461ThrGlu: 3.461 ± 0.057	3.105ThrPhe: 3.105 ± 0.052	4.159ThrGly: 4.159 ± 0.068	1.067ThrHis: 1.067 ± 0.028	4.447ThrIle: 4.447 ± 0.071	3.849ThrLys: 3.849 ± 0.077	5.705ThrLeu: 5.705 ± 0.078	1.153ThrMet: 1.153 ± 0.029	3.161ThrAsn: 3.161 ± 0.097	2.512ThrPro: 2.512 ± 0.05	2.015ThrGln: 2.015 ± 0.041	1.719ThrArg: 1.719 ± 0.041	3.517ThrSer: 3.517 ± 0.061	3.623ThrThr: 3.623 ± 0.076	4.19ThrVal: 4.19 ± 0.104	0.601ThrTrp: 0.601 ± 0.024	2.454ThrTyr: 2.454 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	4.953ValAla: 4.953 ± 0.067	0.528ValCys: 0.528 ± 0.02	3.768ValAsp: 3.768 ± 0.058	3.601ValGlu: 3.601 ± 0.065	3.598ValPhe: 3.598 ± 0.065	4.223ValGly: 4.223 ± 0.064	1.251ValHis: 1.251 ± 0.038	4.239ValIle: 4.239 ± 0.061	3.935ValLys: 3.935 ± 0.064	6.671ValLeu: 6.671 ± 0.097	1.447ValMet: 1.447 ± 0.034	3.381ValAsn: 3.381 ± 0.059	2.611ValPro: 2.611 ± 0.054	2.147ValGln: 2.147 ± 0.04	2.369ValArg: 2.369 ± 0.051	4.247ValSer: 4.247 ± 0.07	3.842ValThr: 3.842 ± 0.092	4.669ValVal: 4.669 ± 0.067	0.666ValTrp: 0.666 ± 0.026	2.307ValTyr: 2.307 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.674TrpAla: 0.674 ± 0.022	0.112TrpCys: 0.112 ± 0.009	0.69TrpAsp: 0.69 ± 0.03	0.697TrpGlu: 0.697 ± 0.025	0.61TrpPhe: 0.61 ± 0.026	0.778TrpGly: 0.778 ± 0.032	0.271TrpHis: 0.271 ± 0.018	0.652TrpIle: 0.652 ± 0.028	0.798TrpLys: 0.798 ± 0.029	1.147TrpLeu: 1.147 ± 0.036	0.354TrpMet: 0.354 ± 0.017	0.737TrpAsn: 0.737 ± 0.034	0.305TrpPro: 0.305 ± 0.019	0.531TrpGln: 0.531 ± 0.021	0.471TrpArg: 0.471 ± 0.021	0.661TrpSer: 0.661 ± 0.026	0.577TrpThr: 0.577 ± 0.026	0.726TrpVal: 0.726 ± 0.027	0.191TrpTrp: 0.191 ± 0.015	0.443TrpTyr: 0.443 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.664TyrAla: 2.664 ± 0.055	0.317TyrCys: 0.317 ± 0.016	2.301TyrAsp: 2.301 ± 0.049	2.237TyrGlu: 2.237 ± 0.048	2.31TyrPhe: 2.31 ± 0.048	2.811TyrGly: 2.811 ± 0.048	0.925TyrHis: 0.925 ± 0.028	2.187TyrIle: 2.187 ± 0.046	2.375TyrLys: 2.375 ± 0.049	3.797TyrLeu: 3.797 ± 0.067	0.708TyrMet: 0.708 ± 0.026	1.952TyrAsn: 1.952 ± 0.042	1.545TyrPro: 1.545 ± 0.041	1.802TyrGln: 1.802 ± 0.039	1.819TyrArg: 1.819 ± 0.041	2.142TyrSer: 2.142 ± 0.044	2.215TyrThr: 2.215 ± 0.045	2.257TyrVal: 2.257 ± 0.04	0.49TyrTrp: 0.49 ± 0.02	1.648TyrTyr: 1.648 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3682 proteins (1160232 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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