Amino acid dipepetide frequency for Beihai sobemo-like virus 12

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.075AlaAla: 4.075 ± 0.733
0.0AlaCys: 0.0 ± 0.0
4.89AlaAsp: 4.89 ± 1.689
3.26AlaGlu: 3.26 ± 1.728
3.26AlaPhe: 3.26 ± 1.126
3.26AlaGly: 3.26 ± 0.301
0.815AlaHis: 0.815 ± 0.432
2.445AlaIle: 2.445 ± 1.558
3.26AlaLys: 3.26 ± 0.301
4.075AlaLeu: 4.075 ± 0.733
0.0AlaMet: 0.0 ± 0.0
1.63AlaAsn: 1.63 ± 0.864
2.445AlaPro: 2.445 ± 0.131
4.075AlaGln: 4.075 ± 0.733
3.26AlaArg: 3.26 ± 0.301
4.89AlaSer: 4.89 ± 0.262
4.075AlaThr: 4.075 ± 2.16
6.52AlaVal: 6.52 ± 0.602
0.815AlaTrp: 0.815 ± 0.995
2.445AlaTyr: 2.445 ± 0.131
0.0AlaXaa: 0.0 ± 0.0
Cys
1.63CysAla: 1.63 ± 0.563
0.0CysCys: 0.0 ± 0.0
1.63CysAsp: 1.63 ± 0.864
0.815CysGlu: 0.815 ± 0.995
0.815CysPhe: 0.815 ± 0.432
0.815CysGly: 0.815 ± 0.995
0.815CysHis: 0.815 ± 0.432
0.815CysIle: 0.815 ± 0.432
2.445CysLys: 2.445 ± 0.131
1.63CysLeu: 1.63 ± 0.864
0.0CysMet: 0.0 ± 0.0
0.815CysAsn: 0.815 ± 0.432
0.815CysPro: 0.815 ± 0.995
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.815CysTyr: 0.815 ± 0.995
0.0CysXaa: 0.0 ± 0.0
Asp
0.815AspAla: 0.815 ± 0.995
0.815AspCys: 0.815 ± 0.995
5.705AspAsp: 5.705 ± 0.17
3.26AspGlu: 3.26 ± 0.301
2.445AspPhe: 2.445 ± 0.131
4.075AspGly: 4.075 ± 2.16
0.815AspHis: 0.815 ± 0.995
7.335AspIle: 7.335 ± 1.035
1.63AspLys: 1.63 ± 0.563
3.26AspLeu: 3.26 ± 0.301
1.63AspMet: 1.63 ± 0.864
2.445AspAsn: 2.445 ± 0.131
4.89AspPro: 4.89 ± 1.689
1.63AspGln: 1.63 ± 0.563
5.705AspArg: 5.705 ± 2.684
4.89AspSer: 4.89 ± 1.165
4.89AspThr: 4.89 ± 1.165
3.26AspVal: 3.26 ± 0.301
2.445AspTrp: 2.445 ± 1.558
1.63AspTyr: 1.63 ± 0.864
0.0AspXaa: 0.0 ± 0.0
Glu
2.445GluAla: 2.445 ± 1.296
0.0GluCys: 0.0 ± 0.0
4.075GluAsp: 4.075 ± 0.694
4.075GluGlu: 4.075 ± 0.733
2.445GluPhe: 2.445 ± 1.558
5.705GluGly: 5.705 ± 1.597
2.445GluHis: 2.445 ± 0.131
7.335GluIle: 7.335 ± 1.035
4.075GluLys: 4.075 ± 0.733
4.075GluLeu: 4.075 ± 0.694
1.63GluMet: 1.63 ± 1.99
3.26GluAsn: 3.26 ± 1.728
1.63GluPro: 1.63 ± 1.99
3.26GluGln: 3.26 ± 1.728
3.26GluArg: 3.26 ± 1.728
4.89GluSer: 4.89 ± 2.592
1.63GluThr: 1.63 ± 1.99
2.445GluVal: 2.445 ± 1.558
0.0GluTrp: 0.0 ± 0.0
0.815GluTyr: 0.815 ± 0.432
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.815PheCys: 0.815 ± 0.432
4.89PheAsp: 4.89 ± 0.262
5.705PheGlu: 5.705 ± 1.257
2.445PhePhe: 2.445 ± 0.131
2.445PheGly: 2.445 ± 0.131
0.0PheHis: 0.0 ± 0.0
3.26PheIle: 3.26 ± 0.301
1.63PheLys: 1.63 ± 1.99
7.335PheLeu: 7.335 ± 1.035
0.815PheMet: 0.815 ± 0.995
1.63PheAsn: 1.63 ± 0.563
2.445PhePro: 2.445 ± 1.296
1.63PheGln: 1.63 ± 0.864
0.815PheArg: 0.815 ± 0.432
0.815PheSer: 0.815 ± 0.432
1.63PheThr: 1.63 ± 0.563
4.89PheVal: 4.89 ± 3.116
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.89GlyAla: 4.89 ± 0.262
0.0GlyCys: 0.0 ± 0.0
3.26GlyAsp: 3.26 ± 1.126
1.63GlyGlu: 1.63 ± 0.864
4.075GlyPhe: 4.075 ± 0.733
2.445GlyGly: 2.445 ± 2.985
0.0GlyHis: 0.0 ± 0.0
3.26GlyIle: 3.26 ± 0.301
7.335GlyLys: 7.335 ± 3.889
10.595GlyLeu: 10.595 ± 0.091
2.445GlyMet: 2.445 ± 1.296
1.63GlyAsn: 1.63 ± 0.864
1.63GlyPro: 1.63 ± 0.864
2.445GlyGln: 2.445 ± 0.131
2.445GlyArg: 2.445 ± 2.985
4.075GlySer: 4.075 ± 0.694
4.075GlyThr: 4.075 ± 0.733
3.26GlyVal: 3.26 ± 0.301
2.445GlyTrp: 2.445 ± 1.558
4.075GlyTyr: 4.075 ± 0.694
0.0GlyXaa: 0.0 ± 0.0
His
0.815HisAla: 0.815 ± 0.995
0.815HisCys: 0.815 ± 0.432
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.815HisPhe: 0.815 ± 0.432
0.815HisGly: 0.815 ± 0.995
2.445HisHis: 2.445 ± 0.131
3.26HisIle: 3.26 ± 2.553
2.445HisLys: 2.445 ± 2.985
1.63HisLeu: 1.63 ± 0.864
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.445HisPro: 2.445 ± 1.558
0.815HisGln: 0.815 ± 0.995
1.63HisArg: 1.63 ± 0.563
0.815HisSer: 0.815 ± 0.432
0.815HisThr: 0.815 ± 0.432
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.815HisTyr: 0.815 ± 0.432
0.0HisXaa: 0.0 ± 0.0
Ile
4.89IleAla: 4.89 ± 1.165
3.26IleCys: 3.26 ± 1.126
5.705IleAsp: 5.705 ± 1.597
2.445IleGlu: 2.445 ± 0.131
0.815IlePhe: 0.815 ± 0.995
4.075IleGly: 4.075 ± 2.121
1.63IleHis: 1.63 ± 0.563
3.26IleIle: 3.26 ± 0.301
4.075IleLys: 4.075 ± 0.694
5.705IleLeu: 5.705 ± 0.17
3.26IleMet: 3.26 ± 1.126
2.445IleAsn: 2.445 ± 1.558
3.26IlePro: 3.26 ± 0.301
3.26IleGln: 3.26 ± 0.301
4.075IleArg: 4.075 ± 0.733
4.89IleSer: 4.89 ± 2.592
4.075IleThr: 4.075 ± 2.16
6.52IleVal: 6.52 ± 2.252
0.815IleTrp: 0.815 ± 0.432
3.26IleTyr: 3.26 ± 0.301
0.0IleXaa: 0.0 ± 0.0
Lys
3.26LysAla: 3.26 ± 0.301
0.815LysCys: 0.815 ± 0.432
2.445LysAsp: 2.445 ± 1.558
4.075LysGlu: 4.075 ± 0.733
2.445LysPhe: 2.445 ± 1.296
4.89LysGly: 4.89 ± 2.592
0.0LysHis: 0.0 ± 0.0
4.89LysIle: 4.89 ± 0.262
7.335LysLys: 7.335 ± 2.462
4.89LysLeu: 4.89 ± 1.689
2.445LysMet: 2.445 ± 1.799
4.075LysAsn: 4.075 ± 2.16
1.63LysPro: 1.63 ± 0.563
6.52LysGln: 6.52 ± 2.029
3.26LysArg: 3.26 ± 0.301
5.705LysSer: 5.705 ± 1.257
2.445LysThr: 2.445 ± 0.131
7.335LysVal: 7.335 ± 1.035
0.815LysTrp: 0.815 ± 0.432
1.63LysTyr: 1.63 ± 0.563
0.0LysXaa: 0.0 ± 0.0
Leu
1.63LeuAla: 1.63 ± 0.864
0.0LeuCys: 0.0 ± 0.0
5.705LeuAsp: 5.705 ± 4.111
6.52LeuGlu: 6.52 ± 2.029
4.075LeuPhe: 4.075 ± 0.733
10.595LeuGly: 10.595 ± 2.763
1.63LeuHis: 1.63 ± 0.563
4.89LeuIle: 4.89 ± 3.116
8.15LeuLys: 8.15 ± 0.04
7.335LeuLeu: 7.335 ± 2.462
2.445LeuMet: 2.445 ± 0.131
1.63LeuAsn: 1.63 ± 0.864
4.89LeuPro: 4.89 ± 0.262
5.705LeuGln: 5.705 ± 1.597
4.89LeuArg: 4.89 ± 1.165
5.705LeuSer: 5.705 ± 1.597
7.335LeuThr: 7.335 ± 0.393
4.89LeuVal: 4.89 ± 1.165
2.445LeuTrp: 2.445 ± 0.131
4.075LeuTyr: 4.075 ± 0.733
0.0LeuXaa: 0.0 ± 0.0
Met
2.445MetAla: 2.445 ± 1.558
0.815MetCys: 0.815 ± 0.995
3.26MetAsp: 3.26 ± 0.301
1.63MetGlu: 1.63 ± 0.563
0.0MetPhe: 0.0 ± 0.0
1.63MetGly: 1.63 ± 0.563
3.26MetHis: 3.26 ± 2.553
3.26MetIle: 3.26 ± 1.728
0.0MetLys: 0.0 ± 0.0
0.815MetLeu: 0.815 ± 0.995
0.0MetMet: 0.0 ± 0.0
3.26MetAsn: 3.26 ± 1.126
0.815MetPro: 0.815 ± 0.995
0.815MetGln: 0.815 ± 0.432
0.815MetArg: 0.815 ± 0.995
1.63MetSer: 1.63 ± 0.864
1.63MetThr: 1.63 ± 1.99
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.445AsnAla: 2.445 ± 1.296
0.815AsnCys: 0.815 ± 0.995
0.815AsnAsp: 0.815 ± 0.432
3.26AsnGlu: 3.26 ± 0.301
4.075AsnPhe: 4.075 ± 0.733
2.445AsnGly: 2.445 ± 0.131
0.0AsnHis: 0.0 ± 0.0
4.075AsnIle: 4.075 ± 0.694
1.63AsnLys: 1.63 ± 0.563
4.075AsnLeu: 4.075 ± 2.16
0.0AsnMet: 0.0 ± 0.0
3.26AsnAsn: 3.26 ± 2.553
0.0AsnPro: 0.0 ± 0.0
0.0AsnGln: 0.0 ± 0.0
2.445AsnArg: 2.445 ± 0.131
3.26AsnSer: 3.26 ± 0.301
1.63AsnThr: 1.63 ± 0.864
0.815AsnVal: 0.815 ± 0.432
0.815AsnTrp: 0.815 ± 0.432
0.815AsnTyr: 0.815 ± 0.432
0.0AsnXaa: 0.0 ± 0.0
Pro
4.89ProAla: 4.89 ± 0.262
0.815ProCys: 0.815 ± 0.995
2.445ProAsp: 2.445 ± 0.131
3.26ProGlu: 3.26 ± 1.126
1.63ProPhe: 1.63 ± 0.563
3.26ProGly: 3.26 ± 1.126
0.815ProHis: 0.815 ± 0.432
3.26ProIle: 3.26 ± 0.301
1.63ProLys: 1.63 ± 0.864
3.26ProLeu: 3.26 ± 0.301
0.815ProMet: 0.815 ± 0.432
0.815ProAsn: 0.815 ± 0.995
1.63ProPro: 1.63 ± 1.99
0.0ProGln: 0.0 ± 0.0
2.445ProArg: 2.445 ± 1.296
2.445ProSer: 2.445 ± 1.558
0.815ProThr: 0.815 ± 0.432
2.445ProVal: 2.445 ± 0.131
1.63ProTrp: 1.63 ± 1.99
0.815ProTyr: 0.815 ± 0.995
0.0ProXaa: 0.0 ± 0.0
Gln
2.445GlnAla: 2.445 ± 0.131
1.63GlnCys: 1.63 ± 0.864
3.26GlnAsp: 3.26 ± 1.728
2.445GlnGlu: 2.445 ± 0.131
0.0GlnPhe: 0.0 ± 0.0
0.815GlnGly: 0.815 ± 0.432
0.815GlnHis: 0.815 ± 0.432
2.445GlnIle: 2.445 ± 0.131
3.26GlnLys: 3.26 ± 0.301
8.965GlnLeu: 8.965 ± 0.472
0.815GlnMet: 0.815 ± 0.432
0.815GlnAsn: 0.815 ± 0.432
1.63GlnPro: 1.63 ± 0.563
2.445GlnGln: 2.445 ± 1.296
0.815GlnArg: 0.815 ± 0.432
3.26GlnSer: 3.26 ± 1.728
3.26GlnThr: 3.26 ± 1.728
2.445GlnVal: 2.445 ± 1.296
1.63GlnTrp: 1.63 ± 0.563
0.815GlnTyr: 0.815 ± 0.432
0.0GlnXaa: 0.0 ± 0.0
Arg
4.89ArgAla: 4.89 ± 2.592
0.815ArgCys: 0.815 ± 0.432
0.815ArgAsp: 0.815 ± 0.432
2.445ArgGlu: 2.445 ± 2.985
1.63ArgPhe: 1.63 ± 0.563
1.63ArgGly: 1.63 ± 0.864
0.0ArgHis: 0.0 ± 0.0
2.445ArgIle: 2.445 ± 1.558
4.075ArgLys: 4.075 ± 0.733
3.26ArgLeu: 3.26 ± 0.301
2.445ArgMet: 2.445 ± 2.985
3.26ArgAsn: 3.26 ± 1.728
1.63ArgPro: 1.63 ± 0.864
1.63ArgGln: 1.63 ± 0.864
2.445ArgArg: 2.445 ± 1.296
4.89ArgSer: 4.89 ± 1.165
1.63ArgThr: 1.63 ± 0.864
3.26ArgVal: 3.26 ± 0.301
0.815ArgTrp: 0.815 ± 0.995
2.445ArgTyr: 2.445 ± 1.558
0.0ArgXaa: 0.0 ± 0.0
Ser
3.26SerAla: 3.26 ± 0.301
1.63SerCys: 1.63 ± 0.864
4.075SerAsp: 4.075 ± 0.733
3.26SerGlu: 3.26 ± 0.301
2.445SerPhe: 2.445 ± 1.296
4.89SerGly: 4.89 ± 1.165
1.63SerHis: 1.63 ± 1.99
3.26SerIle: 3.26 ± 1.728
4.075SerLys: 4.075 ± 0.733
5.705SerLeu: 5.705 ± 0.17
1.63SerMet: 1.63 ± 0.864
3.26SerAsn: 3.26 ± 1.728
3.26SerPro: 3.26 ± 0.301
3.26SerGln: 3.26 ± 1.728
1.63SerArg: 1.63 ± 0.864
9.78SerSer: 9.78 ± 0.523
4.075SerThr: 4.075 ± 2.16
2.445SerVal: 2.445 ± 0.131
4.075SerTrp: 4.075 ± 0.694
6.52SerTyr: 6.52 ± 2.252
0.0SerXaa: 0.0 ± 0.0
Thr
3.26ThrAla: 3.26 ± 0.301
0.815ThrCys: 0.815 ± 0.432
3.26ThrAsp: 3.26 ± 0.301
4.89ThrGlu: 4.89 ± 2.592
3.26ThrPhe: 3.26 ± 0.301
1.63ThrGly: 1.63 ± 0.563
0.815ThrHis: 0.815 ± 0.432
4.075ThrIle: 4.075 ± 0.694
4.89ThrLys: 4.89 ± 2.592
4.89ThrLeu: 4.89 ± 1.165
0.815ThrMet: 0.815 ± 0.995
0.815ThrAsn: 0.815 ± 0.995
0.815ThrPro: 0.815 ± 0.432
4.075ThrGln: 4.075 ± 2.16
1.63ThrArg: 1.63 ± 0.563
6.52ThrSer: 6.52 ± 2.252
7.335ThrThr: 7.335 ± 1.82
2.445ThrVal: 2.445 ± 1.558
0.815ThrTrp: 0.815 ± 0.432
0.815ThrTyr: 0.815 ± 0.432
0.0ThrXaa: 0.0 ± 0.0
Val
7.335ValAla: 7.335 ± 0.393
0.0ValCys: 0.0 ± 0.0
4.075ValAsp: 4.075 ± 2.16
4.075ValGlu: 4.075 ± 0.694
3.26ValPhe: 3.26 ± 3.98
8.15ValGly: 8.15 ± 1.387
0.0ValHis: 0.0 ± 0.0
4.075ValIle: 4.075 ± 2.16
4.075ValLys: 4.075 ± 0.733
6.52ValLeu: 6.52 ± 2.252
1.63ValMet: 1.63 ± 0.563
0.0ValAsn: 0.0 ± 0.0
1.63ValPro: 1.63 ± 0.563
0.815ValGln: 0.815 ± 0.995
2.445ValArg: 2.445 ± 1.296
2.445ValSer: 2.445 ± 1.296
3.26ValThr: 3.26 ± 2.553
2.445ValVal: 2.445 ± 1.296
0.815ValTrp: 0.815 ± 0.432
1.63ValTyr: 1.63 ± 0.864
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.63TrpAsp: 1.63 ± 0.563
1.63TrpGlu: 1.63 ± 0.864
0.815TrpPhe: 0.815 ± 0.995
2.445TrpGly: 2.445 ± 1.558
0.815TrpHis: 0.815 ± 0.995
2.445TrpIle: 2.445 ± 0.131
1.63TrpLys: 1.63 ± 0.563
1.63TrpLeu: 1.63 ± 0.563
0.815TrpMet: 0.815 ± 0.298
0.0TrpAsn: 0.0 ± 0.0
0.815TrpPro: 0.815 ± 0.995
0.0TrpGln: 0.0 ± 0.0
1.63TrpArg: 1.63 ± 0.563
1.63TrpSer: 1.63 ± 0.864
0.815TrpThr: 0.815 ± 0.995
1.63TrpVal: 1.63 ± 0.563
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.075TyrAla: 4.075 ± 0.694
0.0TyrCys: 0.0 ± 0.0
1.63TyrAsp: 1.63 ± 0.563
0.815TyrGlu: 0.815 ± 0.432
2.445TyrPhe: 2.445 ± 0.131
0.0TyrGly: 0.0 ± 0.0
1.63TyrHis: 1.63 ± 1.99
1.63TyrIle: 1.63 ± 0.864
3.26TyrLys: 3.26 ± 0.301
4.89TyrLeu: 4.89 ± 2.592
1.63TyrMet: 1.63 ± 1.99
1.63TyrAsn: 1.63 ± 0.563
0.815TyrPro: 0.815 ± 0.432
1.63TyrGln: 1.63 ± 0.563
0.815TyrArg: 0.815 ± 0.432
1.63TyrSer: 1.63 ± 0.864
2.445TyrThr: 2.445 ± 0.131
1.63TyrVal: 1.63 ± 0.563
0.815TyrTrp: 0.815 ± 0.995
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1228 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski