Amino acid dipepetide frequency for Wenling crustacean virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.683AlaAla: 6.683 ± 1.622
0.535AlaCys: 0.535 ± 0.219
3.475AlaAsp: 3.475 ± 1.976
4.277AlaGlu: 4.277 ± 0.479
2.406AlaPhe: 2.406 ± 1.058
4.812AlaGly: 4.812 ± 0.588
1.069AlaHis: 1.069 ± 0.323
3.208AlaIle: 3.208 ± 1.744
3.208AlaLys: 3.208 ± 1.027
8.287AlaLeu: 8.287 ± 2.135
2.138AlaMet: 2.138 ± 0.57
1.604AlaAsn: 1.604 ± 0.915
4.01AlaPro: 4.01 ± 1.45
2.94AlaGln: 2.94 ± 1.026
2.138AlaArg: 2.138 ± 0.949
5.613AlaSer: 5.613 ± 1.362
4.544AlaThr: 4.544 ± 0.827
1.604AlaVal: 1.604 ± 0.658
0.802AlaTrp: 0.802 ± 0.335
1.069AlaTyr: 1.069 ± 0.61
0.0AlaXaa: 0.0 ± 0.0
Cys
0.267CysAla: 0.267 ± 0.292
0.267CysCys: 0.267 ± 0.148
0.802CysAsp: 0.802 ± 0.494
0.535CysGlu: 0.535 ± 0.528
0.267CysPhe: 0.267 ± 0.343
0.802CysGly: 0.802 ± 0.697
0.0CysHis: 0.0 ± 0.0
1.337CysIle: 1.337 ± 0.427
0.0CysLys: 0.0 ± 0.0
1.337CysLeu: 1.337 ± 0.526
0.535CysMet: 0.535 ± 0.305
0.535CysAsn: 0.535 ± 0.219
0.535CysPro: 0.535 ± 0.296
1.069CysGln: 1.069 ± 0.323
0.535CysArg: 0.535 ± 0.296
2.138CysSer: 2.138 ± 0.764
1.604CysThr: 1.604 ± 0.431
0.267CysVal: 0.267 ± 0.402
0.535CysTrp: 0.535 ± 0.219
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.138AspAla: 2.138 ± 0.56
0.802AspCys: 0.802 ± 0.441
5.346AspAsp: 5.346 ± 2.74
2.673AspGlu: 2.673 ± 1.405
1.604AspPhe: 1.604 ± 0.243
2.94AspGly: 2.94 ± 0.654
2.406AspHis: 2.406 ± 0.621
3.208AspIle: 3.208 ± 1.093
2.94AspLys: 2.94 ± 0.496
7.217AspLeu: 7.217 ± 1.295
0.535AspMet: 0.535 ± 0.465
1.337AspAsn: 1.337 ± 0.309
2.673AspPro: 2.673 ± 0.904
1.604AspGln: 1.604 ± 0.504
1.871AspArg: 1.871 ± 0.516
3.208AspSer: 3.208 ± 0.982
2.138AspThr: 2.138 ± 0.586
3.208AspVal: 3.208 ± 0.891
1.604AspTrp: 1.604 ± 0.889
1.604AspTyr: 1.604 ± 0.58
0.0AspXaa: 0.0 ± 0.0
Glu
5.346GluAla: 5.346 ± 1.591
0.267GluCys: 0.267 ± 0.148
4.01GluAsp: 4.01 ± 1.54
5.079GluGlu: 5.079 ± 1.643
2.406GluPhe: 2.406 ± 0.53
6.148GluGly: 6.148 ± 0.486
0.802GluHis: 0.802 ± 0.233
2.673GluIle: 2.673 ± 0.445
3.742GluLys: 3.742 ± 1.631
2.94GluLeu: 2.94 ± 0.37
1.604GluMet: 1.604 ± 0.323
2.138GluAsn: 2.138 ± 0.744
1.871GluPro: 1.871 ± 0.571
1.871GluGln: 1.871 ± 0.543
2.406GluArg: 2.406 ± 0.409
6.415GluSer: 6.415 ± 1.332
5.079GluThr: 5.079 ± 1.237
5.079GluVal: 5.079 ± 1.938
1.069GluTrp: 1.069 ± 0.327
0.802GluTyr: 0.802 ± 0.76
0.0GluXaa: 0.0 ± 0.0
Phe
1.069PheAla: 1.069 ± 0.672
0.267PheCys: 0.267 ± 0.292
1.337PheAsp: 1.337 ± 0.578
1.604PheGlu: 1.604 ± 0.378
1.604PhePhe: 1.604 ± 0.656
1.871PheGly: 1.871 ± 0.486
0.802PheHis: 0.802 ± 0.329
2.406PheIle: 2.406 ± 0.669
1.604PheLys: 1.604 ± 0.243
4.277PheLeu: 4.277 ± 1.216
0.267PheMet: 0.267 ± 0.148
1.069PheAsn: 1.069 ± 0.437
3.208PhePro: 3.208 ± 1.16
2.673PheGln: 2.673 ± 0.856
2.138PheArg: 2.138 ± 0.931
3.475PheSer: 3.475 ± 0.918
1.604PheThr: 1.604 ± 0.465
2.673PheVal: 2.673 ± 1.26
0.535PheTrp: 0.535 ± 0.305
1.069PheTyr: 1.069 ± 0.782
0.0PheXaa: 0.0 ± 0.0
Gly
1.871GlyAla: 1.871 ± 0.424
0.267GlyCys: 0.267 ± 0.343
4.277GlyAsp: 4.277 ± 1.112
4.01GlyGlu: 4.01 ± 0.879
3.475GlyPhe: 3.475 ± 0.779
3.742GlyGly: 3.742 ± 0.362
1.604GlyHis: 1.604 ± 0.889
5.613GlyIle: 5.613 ± 0.984
4.01GlyLys: 4.01 ± 0.637
5.881GlyLeu: 5.881 ± 1.001
0.535GlyMet: 0.535 ± 0.335
2.406GlyAsn: 2.406 ± 0.524
3.475GlyPro: 3.475 ± 0.428
1.337GlyGln: 1.337 ± 0.309
3.475GlyArg: 3.475 ± 0.5
6.683GlySer: 6.683 ± 1.421
3.475GlyThr: 3.475 ± 1.325
4.544GlyVal: 4.544 ± 0.859
1.337GlyTrp: 1.337 ± 0.578
2.673GlyTyr: 2.673 ± 0.526
0.0GlyXaa: 0.0 ± 0.0
His
1.069HisAla: 1.069 ± 0.475
0.267HisCys: 0.267 ± 0.148
0.802HisAsp: 0.802 ± 0.335
1.337HisGlu: 1.337 ± 0.488
1.069HisPhe: 1.069 ± 0.303
0.802HisGly: 0.802 ± 0.445
0.535HisHis: 0.535 ± 0.296
0.535HisIle: 0.535 ± 0.296
0.535HisLys: 0.535 ± 0.296
4.812HisLeu: 4.812 ± 0.985
0.802HisMet: 0.802 ± 0.335
0.535HisAsn: 0.535 ± 0.219
0.802HisPro: 0.802 ± 0.233
1.069HisGln: 1.069 ± 0.475
2.138HisArg: 2.138 ± 0.921
2.138HisSer: 2.138 ± 0.655
0.802HisThr: 0.802 ± 0.4
1.337HisVal: 1.337 ± 0.804
0.802HisTrp: 0.802 ± 0.445
1.337HisTyr: 1.337 ± 0.46
0.0HisXaa: 0.0 ± 0.0
Ile
4.01IleAla: 4.01 ± 0.999
0.535IleCys: 0.535 ± 0.305
3.208IleAsp: 3.208 ± 0.91
2.94IleGlu: 2.94 ± 0.652
1.871IlePhe: 1.871 ± 0.424
3.742IleGly: 3.742 ± 1.087
1.604IleHis: 1.604 ± 1.328
1.337IleIle: 1.337 ± 0.492
2.94IleLys: 2.94 ± 0.795
8.019IleLeu: 8.019 ± 1.661
1.337IleMet: 1.337 ± 0.326
1.069IleAsn: 1.069 ± 0.493
4.277IlePro: 4.277 ± 0.387
1.871IleGln: 1.871 ± 0.427
4.544IleArg: 4.544 ± 0.795
5.079IleSer: 5.079 ± 1.047
3.475IleThr: 3.475 ± 0.753
2.673IleVal: 2.673 ± 0.818
0.802IleTrp: 0.802 ± 0.364
2.138IleTyr: 2.138 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
4.01LysAla: 4.01 ± 1.228
0.535LysCys: 0.535 ± 0.219
2.138LysAsp: 2.138 ± 1.825
4.01LysGlu: 4.01 ± 0.856
1.871LysPhe: 1.871 ± 0.743
4.01LysGly: 4.01 ± 0.662
2.673LysHis: 2.673 ± 0.611
2.406LysIle: 2.406 ± 0.675
4.544LysLys: 4.544 ± 0.768
4.812LysLeu: 4.812 ± 1.956
1.069LysMet: 1.069 ± 0.493
3.208LysAsn: 3.208 ± 0.764
2.406LysPro: 2.406 ± 0.661
1.069LysGln: 1.069 ± 0.746
3.742LysArg: 3.742 ± 0.916
3.742LysSer: 3.742 ± 0.681
5.613LysThr: 5.613 ± 1.201
3.475LysVal: 3.475 ± 1.184
1.604LysTrp: 1.604 ± 0.658
1.604LysTyr: 1.604 ± 0.811
0.0LysXaa: 0.0 ± 0.0
Leu
7.485LeuAla: 7.485 ± 0.79
1.337LeuCys: 1.337 ± 0.427
2.406LeuAsp: 2.406 ± 0.249
5.613LeuGlu: 5.613 ± 2.243
3.208LeuPhe: 3.208 ± 1.037
7.217LeuGly: 7.217 ± 0.961
1.604LeuHis: 1.604 ± 0.465
6.148LeuIle: 6.148 ± 1.789
6.415LeuLys: 6.415 ± 0.991
11.227LeuLeu: 11.227 ± 1.757
2.406LeuMet: 2.406 ± 0.546
2.406LeuAsn: 2.406 ± 0.877
5.881LeuPro: 5.881 ± 1.389
3.475LeuGln: 3.475 ± 0.948
5.613LeuArg: 5.613 ± 1.296
13.098LeuSer: 13.098 ± 0.503
8.019LeuThr: 8.019 ± 1.269
6.683LeuVal: 6.683 ± 1.147
2.138LeuTrp: 2.138 ± 0.863
4.544LeuTyr: 4.544 ± 1.601
0.0LeuXaa: 0.0 ± 0.0
Met
0.802MetAla: 0.802 ± 0.405
0.802MetCys: 0.802 ± 0.329
0.802MetAsp: 0.802 ± 0.329
0.802MetGlu: 0.802 ± 0.233
1.337MetPhe: 1.337 ± 0.309
1.604MetGly: 1.604 ± 0.871
0.535MetHis: 0.535 ± 0.296
1.337MetIle: 1.337 ± 0.725
3.208MetLys: 3.208 ± 0.925
2.406MetLeu: 2.406 ± 0.603
0.267MetMet: 0.267 ± 0.148
0.802MetAsn: 0.802 ± 0.413
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.337MetArg: 1.337 ± 0.355
0.802MetSer: 0.802 ± 0.413
0.535MetThr: 0.535 ± 0.305
1.604MetVal: 1.604 ± 0.915
0.535MetTrp: 0.535 ± 0.335
0.802MetTyr: 0.802 ± 0.233
0.0MetXaa: 0.0 ± 0.0
Asn
2.138AsnAla: 2.138 ± 1.411
0.535AsnCys: 0.535 ± 0.372
1.337AsnAsp: 1.337 ± 0.309
0.802AsnGlu: 0.802 ± 0.413
1.337AsnPhe: 1.337 ± 0.402
1.604AsnGly: 1.604 ± 0.556
1.337AsnHis: 1.337 ± 0.813
2.138AsnIle: 2.138 ± 0.541
0.802AsnLys: 0.802 ± 0.85
4.544AsnLeu: 4.544 ± 0.602
0.535AsnMet: 0.535 ± 0.425
0.535AsnAsn: 0.535 ± 0.305
1.871AsnPro: 1.871 ± 0.72
1.069AsnGln: 1.069 ± 0.418
0.802AsnArg: 0.802 ± 0.329
2.406AsnSer: 2.406 ± 1.071
1.604AsnThr: 1.604 ± 0.341
1.337AsnVal: 1.337 ± 0.296
1.871AsnTrp: 1.871 ± 0.72
0.802AsnTyr: 0.802 ± 0.445
0.0AsnXaa: 0.0 ± 0.0
Pro
4.01ProAla: 4.01 ± 0.934
0.535ProCys: 0.535 ± 0.219
3.742ProAsp: 3.742 ± 0.752
2.94ProGlu: 2.94 ± 0.775
1.871ProPhe: 1.871 ± 0.424
2.673ProGly: 2.673 ± 0.435
1.337ProHis: 1.337 ± 0.741
2.673ProIle: 2.673 ± 0.435
2.94ProLys: 2.94 ± 0.876
5.346ProLeu: 5.346 ± 0.973
0.802ProMet: 0.802 ± 0.89
0.535ProAsn: 0.535 ± 0.305
4.277ProPro: 4.277 ± 1.536
0.802ProGln: 0.802 ± 0.335
1.337ProArg: 1.337 ± 0.396
6.148ProSer: 6.148 ± 1.559
3.208ProThr: 3.208 ± 0.488
3.475ProVal: 3.475 ± 0.631
1.069ProTrp: 1.069 ± 0.337
1.871ProTyr: 1.871 ± 0.552
0.0ProXaa: 0.0 ± 0.0
Gln
2.406GlnAla: 2.406 ± 0.249
1.069GlnCys: 1.069 ± 0.437
2.406GlnAsp: 2.406 ± 1.072
2.138GlnGlu: 2.138 ± 0.975
0.535GlnPhe: 0.535 ± 0.296
2.673GlnGly: 2.673 ± 0.659
0.0GlnHis: 0.0 ± 0.0
2.138GlnIle: 2.138 ± 0.646
2.406GlnLys: 2.406 ± 0.971
2.138GlnLeu: 2.138 ± 0.863
1.604GlnMet: 1.604 ± 0.334
1.337GlnAsn: 1.337 ± 1.24
0.535GlnPro: 0.535 ± 0.219
0.535GlnGln: 0.535 ± 0.305
1.871GlnArg: 1.871 ± 0.792
3.208GlnSer: 3.208 ± 0.787
2.94GlnThr: 2.94 ± 1.075
2.406GlnVal: 2.406 ± 0.45
0.267GlnTrp: 0.267 ± 0.148
1.337GlnTyr: 1.337 ± 0.355
0.0GlnXaa: 0.0 ± 0.0
Arg
4.277ArgAla: 4.277 ± 1.585
0.802ArgCys: 0.802 ± 0.494
2.406ArgAsp: 2.406 ± 0.524
2.406ArgGlu: 2.406 ± 0.875
2.94ArgPhe: 2.94 ± 1.095
2.138ArgGly: 2.138 ± 0.748
2.138ArgHis: 2.138 ± 0.424
3.475ArgIle: 3.475 ± 0.738
3.742ArgLys: 3.742 ± 1.176
5.613ArgLeu: 5.613 ± 0.561
1.604ArgMet: 1.604 ± 0.445
1.337ArgAsn: 1.337 ± 0.446
1.604ArgPro: 1.604 ± 0.599
1.604ArgGln: 1.604 ± 0.455
2.94ArgArg: 2.94 ± 0.42
3.475ArgSer: 3.475 ± 0.492
2.94ArgThr: 2.94 ± 0.523
5.881ArgVal: 5.881 ± 1.096
0.535ArgTrp: 0.535 ± 0.296
0.267ArgTyr: 0.267 ± 0.292
0.0ArgXaa: 0.0 ± 0.0
Ser
6.415SerAla: 6.415 ± 1.857
2.138SerCys: 2.138 ± 0.922
5.613SerAsp: 5.613 ± 0.857
6.683SerGlu: 6.683 ± 0.878
2.94SerPhe: 2.94 ± 0.914
6.148SerGly: 6.148 ± 0.827
1.604SerHis: 1.604 ± 0.431
4.01SerIle: 4.01 ± 0.643
2.94SerLys: 2.94 ± 1.62
10.96SerLeu: 10.96 ± 1.385
0.802SerMet: 0.802 ± 0.445
2.673SerAsn: 2.673 ± 0.891
3.475SerPro: 3.475 ± 0.318
4.544SerGln: 4.544 ± 1.059
4.01SerArg: 4.01 ± 0.488
13.098SerSer: 13.098 ± 1.937
4.544SerThr: 4.544 ± 1.019
7.217SerVal: 7.217 ± 0.982
2.138SerTrp: 2.138 ± 0.24
4.277SerTyr: 4.277 ± 1.176
0.0SerXaa: 0.0 ± 0.0
Thr
3.208ThrAla: 3.208 ± 0.471
1.069ThrCys: 1.069 ± 0.327
1.337ThrAsp: 1.337 ± 0.988
6.148ThrGlu: 6.148 ± 0.817
1.871ThrPhe: 1.871 ± 0.824
4.277ThrGly: 4.277 ± 1.177
1.604ThrHis: 1.604 ± 0.8
4.544ThrIle: 4.544 ± 0.63
3.208ThrLys: 3.208 ± 0.599
6.95ThrLeu: 6.95 ± 0.951
1.069ThrMet: 1.069 ± 0.746
2.138ThrAsn: 2.138 ± 1.315
4.812ThrPro: 4.812 ± 1.24
1.337ThrGln: 1.337 ± 0.355
3.208ThrArg: 3.208 ± 0.891
5.079ThrSer: 5.079 ± 0.463
2.406ThrThr: 2.406 ± 0.79
3.742ThrVal: 3.742 ± 1.562
1.871ThrTrp: 1.871 ± 0.669
1.871ThrTyr: 1.871 ± 0.568
0.0ThrXaa: 0.0 ± 0.0
Val
4.01ValAla: 4.01 ± 1.034
0.802ValCys: 0.802 ± 0.233
3.208ValAsp: 3.208 ± 0.862
3.208ValGlu: 3.208 ± 0.394
1.604ValPhe: 1.604 ± 0.658
4.812ValGly: 4.812 ± 1.296
0.802ValHis: 0.802 ± 0.364
5.079ValIle: 5.079 ± 1.366
5.346ValLys: 5.346 ± 1.124
6.415ValLeu: 6.415 ± 1.283
1.337ValMet: 1.337 ± 0.492
1.871ValAsn: 1.871 ± 0.417
3.208ValPro: 3.208 ± 0.681
2.673ValGln: 2.673 ± 0.487
4.544ValArg: 4.544 ± 1.019
5.881ValSer: 5.881 ± 2.051
4.01ValThr: 4.01 ± 0.726
4.277ValVal: 4.277 ± 1.711
1.337ValTrp: 1.337 ± 0.427
1.337ValTyr: 1.337 ± 0.427
0.0ValXaa: 0.0 ± 0.0
Trp
1.871TrpAla: 1.871 ± 0.473
0.0TrpCys: 0.0 ± 0.0
1.069TrpAsp: 1.069 ± 0.437
1.604TrpGlu: 1.604 ± 0.889
0.0TrpPhe: 0.0 ± 0.0
1.604TrpGly: 1.604 ± 0.889
0.267TrpHis: 0.267 ± 0.148
0.535TrpIle: 0.535 ± 0.296
2.94TrpLys: 2.94 ± 0.929
0.802TrpLeu: 0.802 ± 0.445
0.267TrpMet: 0.267 ± 0.292
1.069TrpAsn: 1.069 ± 0.672
0.267TrpPro: 0.267 ± 0.148
0.535TrpGln: 0.535 ± 0.296
1.604TrpArg: 1.604 ± 0.334
2.94TrpSer: 2.94 ± 0.428
1.604TrpThr: 1.604 ± 0.46
1.871TrpVal: 1.871 ± 0.403
0.0TrpTrp: 0.0 ± 0.0
0.535TrpTyr: 0.535 ± 0.296
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.337TyrAla: 1.337 ± 0.408
0.535TyrCys: 0.535 ± 0.305
1.337TyrAsp: 1.337 ± 0.309
2.94TyrGlu: 2.94 ± 0.217
1.337TyrPhe: 1.337 ± 0.309
1.069TyrGly: 1.069 ± 0.593
0.802TyrHis: 0.802 ± 0.233
2.673TyrIle: 2.673 ± 0.813
1.069TyrLys: 1.069 ± 0.385
2.94TyrLeu: 2.94 ± 0.769
0.535TyrMet: 0.535 ± 0.305
0.802TyrAsn: 0.802 ± 0.445
2.406TyrPro: 2.406 ± 0.764
1.871TyrGln: 1.871 ± 1.037
1.871TyrArg: 1.871 ± 0.683
1.604TyrSer: 1.604 ± 0.46
1.604TyrThr: 1.604 ± 0.341
2.673TyrVal: 2.673 ± 0.617
0.535TyrTrp: 0.535 ± 0.335
0.267TyrTyr: 0.267 ± 0.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3742 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski