Amino acid dipepetide frequency for Fowl aviadenovirus C

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.653AlaAla: 6.653 ± 1.117
1.603AlaCys: 1.603 ± 0.433
4.248AlaAsp: 4.248 ± 0.361
4.649AlaGlu: 4.649 ± 0.738
3.447AlaPhe: 3.447 ± 0.588
4.489AlaGly: 4.489 ± 0.721
1.363AlaHis: 1.363 ± 0.372
4.409AlaIle: 4.409 ± 0.602
2.645AlaLys: 2.645 ± 0.437
6.974AlaLeu: 6.974 ± 0.859
1.924AlaMet: 1.924 ± 0.521
2.886AlaAsn: 2.886 ± 0.536
4.489AlaPro: 4.489 ± 0.595
2.806AlaGln: 2.806 ± 0.568
3.687AlaArg: 3.687 ± 0.719
5.13AlaSer: 5.13 ± 0.853
4.409AlaThr: 4.409 ± 0.666
4.168AlaVal: 4.168 ± 0.614
0.802AlaTrp: 0.802 ± 0.279
3.046AlaTyr: 3.046 ± 0.463
0.0AlaXaa: 0.0 ± 0.0
Cys
1.202CysAla: 1.202 ± 0.296
0.401CysCys: 0.401 ± 0.245
1.122CysAsp: 1.122 ± 0.353
1.283CysGlu: 1.283 ± 0.411
0.802CysPhe: 0.802 ± 0.232
1.363CysGly: 1.363 ± 0.377
0.962CysHis: 0.962 ± 0.314
0.721CysIle: 0.721 ± 0.239
0.802CysLys: 0.802 ± 0.232
1.283CysLeu: 1.283 ± 0.336
0.481CysMet: 0.481 ± 0.197
1.283CysAsn: 1.283 ± 0.286
1.523CysPro: 1.523 ± 0.368
0.401CysGln: 0.401 ± 0.228
1.202CysArg: 1.202 ± 0.411
1.764CysSer: 1.764 ± 0.433
0.962CysThr: 0.962 ± 0.292
0.641CysVal: 0.641 ± 0.18
0.321CysTrp: 0.321 ± 0.149
0.641CysTyr: 0.641 ± 0.173
0.0CysXaa: 0.0 ± 0.0
Asp
4.729AspAla: 4.729 ± 0.774
0.561AspCys: 0.561 ± 0.241
2.485AspAsp: 2.485 ± 0.339
3.607AspGlu: 3.607 ± 0.816
1.603AspPhe: 1.603 ± 0.329
3.046AspGly: 3.046 ± 0.493
0.882AspHis: 0.882 ± 0.267
2.725AspIle: 2.725 ± 0.454
1.603AspLys: 1.603 ± 0.307
5.291AspLeu: 5.291 ± 0.622
2.004AspMet: 2.004 ± 0.448
2.084AspAsn: 2.084 ± 0.525
5.13AspPro: 5.13 ± 0.684
1.924AspGln: 1.924 ± 0.293
3.768AspArg: 3.768 ± 0.522
3.527AspSer: 3.527 ± 0.612
3.607AspThr: 3.607 ± 0.549
2.325AspVal: 2.325 ± 0.34
0.641AspTrp: 0.641 ± 0.233
2.645AspTyr: 2.645 ± 0.351
0.0AspXaa: 0.0 ± 0.0
Glu
3.928GluAla: 3.928 ± 0.729
0.962GluCys: 0.962 ± 0.409
3.126GluAsp: 3.126 ± 0.478
5.13GluGlu: 5.13 ± 1.077
2.164GluPhe: 2.164 ± 0.46
2.966GluGly: 2.966 ± 0.44
2.004GluHis: 2.004 ± 0.525
3.367GluIle: 3.367 ± 0.625
2.004GluLys: 2.004 ± 0.435
6.413GluLeu: 6.413 ± 0.711
1.443GluMet: 1.443 ± 0.358
2.325GluAsn: 2.325 ± 0.446
3.046GluPro: 3.046 ± 0.534
2.565GluGln: 2.565 ± 0.51
3.527GluArg: 3.527 ± 0.593
2.405GluSer: 2.405 ± 0.303
3.206GluThr: 3.206 ± 0.597
4.248GluVal: 4.248 ± 0.563
0.641GluTrp: 0.641 ± 0.201
1.363GluTyr: 1.363 ± 0.354
0.0GluXaa: 0.0 ± 0.0
Phe
2.485PheAla: 2.485 ± 0.445
0.962PheCys: 0.962 ± 0.404
3.287PheAsp: 3.287 ± 0.803
2.485PheGlu: 2.485 ± 0.45
2.084PhePhe: 2.084 ± 0.479
1.443PheGly: 1.443 ± 0.369
1.523PheHis: 1.523 ± 0.316
1.844PheIle: 1.844 ± 0.482
2.164PheLys: 2.164 ± 0.473
4.008PheLeu: 4.008 ± 0.746
1.764PheMet: 1.764 ± 0.34
1.683PheAsn: 1.683 ± 0.343
2.645PhePro: 2.645 ± 0.499
1.443PheGln: 1.443 ± 0.392
2.645PheArg: 2.645 ± 0.381
3.447PheSer: 3.447 ± 0.469
2.004PheThr: 2.004 ± 0.258
2.485PheVal: 2.485 ± 0.397
0.641PheTrp: 0.641 ± 0.186
2.244PheTyr: 2.244 ± 0.381
0.0PheXaa: 0.0 ± 0.0
Gly
6.012GlyAla: 6.012 ± 0.763
0.802GlyCys: 0.802 ± 0.338
2.886GlyAsp: 2.886 ± 0.389
3.607GlyGlu: 3.607 ± 0.767
2.004GlyPhe: 2.004 ± 0.471
6.172GlyGly: 6.172 ± 1.432
0.802GlyHis: 0.802 ± 0.317
2.244GlyIle: 2.244 ± 0.476
1.844GlyLys: 1.844 ± 0.333
5.691GlyLeu: 5.691 ± 0.914
1.603GlyMet: 1.603 ± 0.318
2.325GlyAsn: 2.325 ± 0.438
3.768GlyPro: 3.768 ± 0.573
2.565GlyGln: 2.565 ± 0.543
4.248GlyArg: 4.248 ± 0.719
4.168GlySer: 4.168 ± 0.649
4.409GlyThr: 4.409 ± 0.649
4.409GlyVal: 4.409 ± 0.648
1.202GlyTrp: 1.202 ± 0.232
2.485GlyTyr: 2.485 ± 0.499
0.0GlyXaa: 0.0 ± 0.0
His
1.764HisAla: 1.764 ± 0.361
1.683HisCys: 1.683 ± 0.469
1.202HisAsp: 1.202 ± 0.188
1.042HisGlu: 1.042 ± 0.344
0.802HisPhe: 0.802 ± 0.263
1.844HisGly: 1.844 ± 0.491
0.721HisHis: 0.721 ± 0.249
1.202HisIle: 1.202 ± 0.237
0.641HisLys: 0.641 ± 0.233
1.924HisLeu: 1.924 ± 0.39
0.401HisMet: 0.401 ± 0.161
1.523HisAsn: 1.523 ± 0.341
1.523HisPro: 1.523 ± 0.318
0.641HisGln: 0.641 ± 0.267
1.683HisArg: 1.683 ± 0.326
2.084HisSer: 2.084 ± 0.474
1.122HisThr: 1.122 ± 0.221
1.603HisVal: 1.603 ± 0.469
0.401HisTrp: 0.401 ± 0.185
0.802HisTyr: 0.802 ± 0.222
0.0HisXaa: 0.0 ± 0.0
Ile
3.046IleAla: 3.046 ± 0.497
0.802IleCys: 0.802 ± 0.238
2.485IleAsp: 2.485 ± 0.434
2.645IleGlu: 2.645 ± 0.542
1.523IlePhe: 1.523 ± 0.403
2.325IleGly: 2.325 ± 0.51
1.523IleHis: 1.523 ± 0.341
1.363IleIle: 1.363 ± 0.322
1.683IleLys: 1.683 ± 0.448
3.447IleLeu: 3.447 ± 0.642
1.042IleMet: 1.042 ± 0.295
2.405IleAsn: 2.405 ± 0.477
3.367IlePro: 3.367 ± 0.518
1.844IleGln: 1.844 ± 0.49
2.645IleArg: 2.645 ± 0.477
3.287IleSer: 3.287 ± 0.433
2.886IleThr: 2.886 ± 0.445
2.725IleVal: 2.725 ± 0.359
0.401IleTrp: 0.401 ± 0.156
1.603IleTyr: 1.603 ± 0.243
0.0IleXaa: 0.0 ± 0.0
Lys
2.485LysAla: 2.485 ± 0.525
0.561LysCys: 0.561 ± 0.156
2.565LysAsp: 2.565 ± 0.477
1.924LysGlu: 1.924 ± 0.327
2.325LysPhe: 2.325 ± 0.446
2.164LysGly: 2.164 ± 0.37
0.962LysHis: 0.962 ± 0.348
0.802LysIle: 0.802 ± 0.265
1.844LysLys: 1.844 ± 0.384
3.287LysLeu: 3.287 ± 0.583
0.962LysMet: 0.962 ± 0.326
1.603LysAsn: 1.603 ± 0.362
2.164LysPro: 2.164 ± 0.462
1.443LysGln: 1.443 ± 0.538
3.447LysArg: 3.447 ± 0.48
1.844LysSer: 1.844 ± 0.376
2.325LysThr: 2.325 ± 0.542
2.244LysVal: 2.244 ± 0.48
0.561LysTrp: 0.561 ± 0.21
1.683LysTyr: 1.683 ± 0.318
0.0LysXaa: 0.0 ± 0.0
Leu
5.611LeuAla: 5.611 ± 0.582
1.523LeuCys: 1.523 ± 0.293
5.21LeuAsp: 5.21 ± 0.591
4.649LeuGlu: 4.649 ± 0.477
4.329LeuPhe: 4.329 ± 0.614
5.371LeuGly: 5.371 ± 0.577
2.325LeuHis: 2.325 ± 0.686
3.527LeuIle: 3.527 ± 0.561
4.729LeuLys: 4.729 ± 0.525
6.974LeuLeu: 6.974 ± 0.692
1.924LeuMet: 1.924 ± 0.414
3.527LeuAsn: 3.527 ± 0.621
4.97LeuPro: 4.97 ± 0.54
5.291LeuGln: 5.291 ± 0.525
6.894LeuArg: 6.894 ± 0.78
5.772LeuSer: 5.772 ± 0.78
6.333LeuThr: 6.333 ± 0.575
5.13LeuVal: 5.13 ± 0.835
1.122LeuTrp: 1.122 ± 0.271
3.928LeuTyr: 3.928 ± 0.723
0.0LeuXaa: 0.0 ± 0.0
Met
2.886MetAla: 2.886 ± 0.661
0.401MetCys: 0.401 ± 0.194
1.202MetAsp: 1.202 ± 0.298
1.764MetGlu: 1.764 ± 0.598
0.962MetPhe: 0.962 ± 0.305
1.363MetGly: 1.363 ± 0.303
1.042MetHis: 1.042 ± 0.287
0.802MetIle: 0.802 ± 0.255
0.802MetLys: 0.802 ± 0.279
2.325MetLeu: 2.325 ± 0.378
0.641MetMet: 0.641 ± 0.176
1.202MetAsn: 1.202 ± 0.287
2.004MetPro: 2.004 ± 0.417
0.802MetGln: 0.802 ± 0.299
1.844MetArg: 1.844 ± 0.572
1.683MetSer: 1.683 ± 0.397
1.202MetThr: 1.202 ± 0.293
2.084MetVal: 2.084 ± 0.379
0.321MetTrp: 0.321 ± 0.17
0.882MetTyr: 0.882 ± 0.274
0.0MetXaa: 0.0 ± 0.0
Asn
3.928AsnAla: 3.928 ± 0.753
0.882AsnCys: 0.882 ± 0.261
1.844AsnAsp: 1.844 ± 0.412
1.283AsnGlu: 1.283 ± 0.383
2.485AsnPhe: 2.485 ± 0.746
2.565AsnGly: 2.565 ± 0.584
0.882AsnHis: 0.882 ± 0.242
2.004AsnIle: 2.004 ± 0.498
1.683AsnLys: 1.683 ± 0.43
2.886AsnLeu: 2.886 ± 0.513
1.202AsnMet: 1.202 ± 0.383
2.084AsnAsn: 2.084 ± 0.463
3.687AsnPro: 3.687 ± 0.571
2.004AsnGln: 2.004 ± 0.381
2.806AsnArg: 2.806 ± 0.549
2.645AsnSer: 2.645 ± 0.606
2.806AsnThr: 2.806 ± 0.691
2.806AsnVal: 2.806 ± 0.691
0.721AsnTrp: 0.721 ± 0.398
2.325AsnTyr: 2.325 ± 0.359
0.0AsnXaa: 0.0 ± 0.0
Pro
4.329ProAla: 4.329 ± 0.558
0.721ProCys: 0.721 ± 0.217
3.687ProAsp: 3.687 ± 0.567
4.489ProGlu: 4.489 ± 0.665
3.928ProPhe: 3.928 ± 0.515
3.046ProGly: 3.046 ± 0.51
2.164ProHis: 2.164 ± 0.357
3.206ProIle: 3.206 ± 0.552
2.565ProLys: 2.565 ± 0.527
5.371ProLeu: 5.371 ± 0.817
2.004ProMet: 2.004 ± 0.457
2.244ProAsn: 2.244 ± 0.51
6.894ProPro: 6.894 ± 1.042
2.565ProGln: 2.565 ± 0.508
3.447ProArg: 3.447 ± 0.404
5.531ProSer: 5.531 ± 0.711
5.291ProThr: 5.291 ± 1.014
3.928ProVal: 3.928 ± 0.664
0.321ProTrp: 0.321 ± 0.126
3.447ProTyr: 3.447 ± 0.506
0.0ProXaa: 0.0 ± 0.0
Gln
2.645GlnAla: 2.645 ± 0.537
0.721GlnCys: 0.721 ± 0.291
0.962GlnAsp: 0.962 ± 0.249
2.645GlnGlu: 2.645 ± 0.434
1.283GlnPhe: 1.283 ± 0.321
2.966GlnGly: 2.966 ± 0.489
1.603GlnHis: 1.603 ± 0.48
1.363GlnIle: 1.363 ± 0.269
1.122GlnLys: 1.122 ± 0.33
4.729GlnLeu: 4.729 ± 0.568
1.202GlnMet: 1.202 ± 0.351
2.164GlnAsn: 2.164 ± 0.425
2.164GlnPro: 2.164 ± 0.513
2.966GlnGln: 2.966 ± 0.735
2.886GlnArg: 2.886 ± 0.578
2.164GlnSer: 2.164 ± 0.314
2.405GlnThr: 2.405 ± 0.376
1.764GlnVal: 1.764 ± 0.36
0.721GlnTrp: 0.721 ± 0.227
2.004GlnTyr: 2.004 ± 0.47
0.0GlnXaa: 0.0 ± 0.0
Arg
4.729ArgAla: 4.729 ± 0.563
1.283ArgCys: 1.283 ± 0.374
3.928ArgAsp: 3.928 ± 0.736
3.287ArgGlu: 3.287 ± 0.514
3.367ArgPhe: 3.367 ± 0.372
4.088ArgGly: 4.088 ± 0.75
1.443ArgHis: 1.443 ± 0.334
2.485ArgIle: 2.485 ± 0.582
2.725ArgLys: 2.725 ± 0.484
4.729ArgLeu: 4.729 ± 0.65
2.004ArgMet: 2.004 ± 0.366
3.046ArgAsn: 3.046 ± 0.787
3.848ArgPro: 3.848 ± 0.685
2.886ArgGln: 2.886 ± 0.619
7.535ArgArg: 7.535 ± 1.568
5.371ArgSer: 5.371 ± 0.859
3.687ArgThr: 3.687 ± 0.572
3.527ArgVal: 3.527 ± 0.55
1.443ArgTrp: 1.443 ± 0.293
2.485ArgTyr: 2.485 ± 0.374
0.0ArgXaa: 0.0 ± 0.0
Ser
5.691SerAla: 5.691 ± 0.713
1.603SerCys: 1.603 ± 0.346
4.168SerAsp: 4.168 ± 0.574
3.928SerGlu: 3.928 ± 0.535
2.485SerPhe: 2.485 ± 0.402
6.092SerGly: 6.092 ± 1.114
1.603SerHis: 1.603 ± 0.377
3.768SerIle: 3.768 ± 0.509
2.164SerLys: 2.164 ± 0.63
5.772SerLeu: 5.772 ± 0.799
1.363SerMet: 1.363 ± 0.446
2.084SerAsn: 2.084 ± 0.351
5.05SerPro: 5.05 ± 0.787
2.405SerGln: 2.405 ± 0.637
4.088SerArg: 4.088 ± 0.696
5.13SerSer: 5.13 ± 0.908
4.008SerThr: 4.008 ± 0.606
4.248SerVal: 4.248 ± 0.555
0.802SerTrp: 0.802 ± 0.264
1.683SerTyr: 1.683 ± 0.578
0.0SerXaa: 0.0 ± 0.0
Thr
5.451ThrAla: 5.451 ± 0.735
0.962ThrCys: 0.962 ± 0.299
3.126ThrAsp: 3.126 ± 0.382
3.447ThrGlu: 3.447 ± 0.401
2.405ThrPhe: 2.405 ± 0.31
5.371ThrGly: 5.371 ± 0.833
0.561ThrHis: 0.561 ± 0.249
2.886ThrIle: 2.886 ± 0.561
1.764ThrLys: 1.764 ± 0.362
5.13ThrLeu: 5.13 ± 0.925
1.122ThrMet: 1.122 ± 0.314
2.806ThrAsn: 2.806 ± 0.628
5.371ThrPro: 5.371 ± 1.117
1.523ThrGln: 1.523 ± 0.44
3.447ThrArg: 3.447 ± 0.476
4.409ThrSer: 4.409 ± 0.589
7.615ThrThr: 7.615 ± 4.015
4.409ThrVal: 4.409 ± 0.704
0.721ThrTrp: 0.721 ± 0.227
2.966ThrTyr: 2.966 ± 0.637
0.0ThrXaa: 0.0 ± 0.0
Val
3.367ValAla: 3.367 ± 0.44
1.363ValCys: 1.363 ± 0.422
3.287ValAsp: 3.287 ± 0.654
2.485ValGlu: 2.485 ± 0.568
2.725ValPhe: 2.725 ± 0.482
3.287ValGly: 3.287 ± 0.461
1.202ValHis: 1.202 ± 0.321
2.485ValIle: 2.485 ± 0.57
1.924ValLys: 1.924 ± 0.412
7.455ValLeu: 7.455 ± 0.64
0.802ValMet: 0.802 ± 0.186
3.206ValAsn: 3.206 ± 0.671
4.81ValPro: 4.81 ± 0.834
2.405ValGln: 2.405 ± 0.518
4.409ValArg: 4.409 ± 0.584
4.329ValSer: 4.329 ± 0.721
3.848ValThr: 3.848 ± 0.706
4.168ValVal: 4.168 ± 0.632
0.721ValTrp: 0.721 ± 0.24
2.565ValTyr: 2.565 ± 0.391
0.0ValXaa: 0.0 ± 0.0
Trp
0.802TrpAla: 0.802 ± 0.245
0.481TrpCys: 0.481 ± 0.242
0.641TrpAsp: 0.641 ± 0.205
0.641TrpGlu: 0.641 ± 0.15
0.721TrpPhe: 0.721 ± 0.254
1.042TrpGly: 1.042 ± 0.292
0.08TrpHis: 0.08 ± 0.081
0.641TrpIle: 0.641 ± 0.16
0.802TrpLys: 0.802 ± 0.298
1.122TrpLeu: 1.122 ± 0.304
0.321TrpMet: 0.321 ± 0.149
0.802TrpAsn: 0.802 ± 0.204
0.561TrpPro: 0.561 ± 0.409
0.641TrpGln: 0.641 ± 0.2
0.802TrpArg: 0.802 ± 0.281
0.882TrpSer: 0.882 ± 0.319
1.122TrpThr: 1.122 ± 0.277
0.962TrpVal: 0.962 ± 0.256
0.0TrpTrp: 0.0 ± 0.0
0.401TrpTyr: 0.401 ± 0.15
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.084TyrAla: 2.084 ± 0.389
0.882TyrCys: 0.882 ± 0.219
2.725TyrAsp: 2.725 ± 0.517
1.844TyrGlu: 1.844 ± 0.496
1.844TyrPhe: 1.844 ± 0.499
2.325TyrGly: 2.325 ± 0.406
0.962TyrHis: 0.962 ± 0.246
1.202TyrIle: 1.202 ± 0.363
1.683TyrLys: 1.683 ± 0.477
4.329TyrLeu: 4.329 ± 0.689
1.924TyrMet: 1.924 ± 0.396
2.244TyrAsn: 2.244 ± 0.585
2.164TyrPro: 2.164 ± 0.32
1.363TyrGln: 1.363 ± 0.418
2.886TyrArg: 2.886 ± 0.599
2.565TyrSer: 2.565 ± 0.471
2.244TyrThr: 2.244 ± 0.464
2.966TyrVal: 2.966 ± 0.486
0.962TyrTrp: 0.962 ± 0.331
1.042TyrTyr: 1.042 ± 0.249
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 37 proteins (12476 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski