Amino acid dipepetide frequency for Vicia cryptic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.797AlaAla: 11.797 ± 8.592
0.907AlaCys: 0.907 ± 0.766
2.722AlaAsp: 2.722 ± 0.445
3.63AlaGlu: 3.63 ± 1.051
2.722AlaPhe: 2.722 ± 0.445
2.722AlaGly: 2.722 ± 1.817
3.63AlaHis: 3.63 ± 1.694
6.352AlaIle: 6.352 ± 1.248
0.0AlaLys: 0.0 ± 0.0
4.537AlaLeu: 4.537 ± 2.46
0.907AlaMet: 0.907 ± 0.606
4.537AlaAsn: 4.537 ± 2.46
7.26AlaPro: 7.26 ± 2.015
6.352AlaGln: 6.352 ± 1.248
3.63AlaArg: 3.63 ± 0.321
4.537AlaSer: 4.537 ± 1.088
5.445AlaThr: 5.445 ± 1.854
2.722AlaVal: 2.722 ± 2.299
2.722AlaTrp: 2.722 ± 0.927
2.722AlaTyr: 2.722 ± 0.445
0.0AlaXaa: 0.0 ± 0.0
Cys
1.815CysAla: 1.815 ± 0.161
0.0CysCys: 0.0 ± 0.0
0.907CysAsp: 0.907 ± 0.766
0.907CysGlu: 0.907 ± 0.606
0.907CysPhe: 0.907 ± 0.766
1.815CysGly: 1.815 ± 0.161
0.0CysHis: 0.0 ± 0.0
0.907CysIle: 0.907 ± 0.606
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.815CysMet: 1.815 ± 0.161
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.907CysArg: 0.907 ± 0.606
0.0CysSer: 0.0 ± 0.0
1.815CysThr: 1.815 ± 1.212
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.722AspAla: 2.722 ± 0.927
0.0AspCys: 0.0 ± 0.0
2.722AspAsp: 2.722 ± 1.817
2.722AspGlu: 2.722 ± 1.817
3.63AspPhe: 3.63 ± 2.423
0.907AspGly: 0.907 ± 0.606
4.537AspHis: 4.537 ± 1.657
2.722AspIle: 2.722 ± 0.445
3.63AspLys: 3.63 ± 2.423
4.537AspLeu: 4.537 ± 2.46
0.0AspMet: 0.0 ± 0.491
0.907AspAsn: 0.907 ± 0.606
1.815AspPro: 1.815 ± 1.212
1.815AspGln: 1.815 ± 0.161
0.907AspArg: 0.907 ± 0.766
6.352AspSer: 6.352 ± 0.124
1.815AspThr: 1.815 ± 1.212
2.722AspVal: 2.722 ± 0.445
2.722AspTrp: 2.722 ± 0.927
1.815AspTyr: 1.815 ± 0.161
0.0AspXaa: 0.0 ± 0.0
Glu
2.722GluAla: 2.722 ± 0.445
0.907GluCys: 0.907 ± 0.766
2.722GluAsp: 2.722 ± 1.817
1.815GluGlu: 1.815 ± 0.161
0.907GluPhe: 0.907 ± 0.606
0.907GluGly: 0.907 ± 0.606
1.815GluHis: 1.815 ± 1.212
6.352GluIle: 6.352 ± 1.496
0.907GluLys: 0.907 ± 0.606
3.63GluLeu: 3.63 ± 1.694
1.815GluMet: 1.815 ± 0.96
0.907GluAsn: 0.907 ± 0.606
2.722GluPro: 2.722 ± 0.927
1.815GluGln: 1.815 ± 1.533
3.63GluArg: 3.63 ± 1.051
0.907GluSer: 0.907 ± 0.606
0.907GluThr: 0.907 ± 0.606
1.815GluVal: 1.815 ± 1.212
0.0GluTrp: 0.0 ± 0.0
5.445GluTyr: 5.445 ± 3.635
0.0GluXaa: 0.0 ± 0.0
Phe
2.722PheAla: 2.722 ± 1.817
0.907PheCys: 0.907 ± 0.606
5.445PheAsp: 5.445 ± 0.482
4.537PheGlu: 4.537 ± 3.029
3.63PhePhe: 3.63 ± 0.321
3.63PheGly: 3.63 ± 1.051
1.815PheHis: 1.815 ± 0.161
6.352PheIle: 6.352 ± 2.868
0.0PheLys: 0.0 ± 0.0
3.63PheLeu: 3.63 ± 1.051
0.0PheMet: 0.0 ± 0.0
5.445PheAsn: 5.445 ± 0.482
3.63PhePro: 3.63 ± 2.423
1.815PheGln: 1.815 ± 1.533
4.537PheArg: 4.537 ± 1.657
3.63PheSer: 3.63 ± 1.051
9.074PheThr: 9.074 ± 4.92
0.907PheVal: 0.907 ± 0.766
0.0PheTrp: 0.0 ± 0.0
1.815PheTyr: 1.815 ± 1.212
0.0PheXaa: 0.0 ± 0.0
Gly
4.537GlyAla: 4.537 ± 2.46
0.907GlyCys: 0.907 ± 0.606
5.445GlyAsp: 5.445 ± 0.482
1.815GlyGlu: 1.815 ± 0.161
5.445GlyPhe: 5.445 ± 0.89
0.907GlyGly: 0.907 ± 0.606
0.907GlyHis: 0.907 ± 0.766
2.722GlyIle: 2.722 ± 0.927
0.0GlyLys: 0.0 ± 0.0
8.167GlyLeu: 8.167 ± 2.708
0.0GlyMet: 0.0 ± 0.0
1.815GlyAsn: 1.815 ± 0.161
4.537GlyPro: 4.537 ± 3.832
0.0GlyGln: 0.0 ± 0.0
1.815GlyArg: 1.815 ± 0.161
2.722GlySer: 2.722 ± 0.927
1.815GlyThr: 1.815 ± 1.533
0.907GlyVal: 0.907 ± 0.766
0.907GlyTrp: 0.907 ± 0.606
5.445GlyTyr: 5.445 ± 2.263
0.0GlyXaa: 0.0 ± 0.0
His
2.722HisAla: 2.722 ± 0.445
0.0HisCys: 0.0 ± 0.0
1.815HisAsp: 1.815 ± 1.212
3.63HisGlu: 3.63 ± 0.321
2.722HisPhe: 2.722 ± 0.445
1.815HisGly: 1.815 ± 0.161
0.907HisHis: 0.907 ± 0.606
2.722HisIle: 2.722 ± 1.817
0.907HisLys: 0.907 ± 0.606
2.722HisLeu: 2.722 ± 0.927
0.0HisMet: 0.0 ± 0.0
2.722HisAsn: 2.722 ± 0.445
1.815HisPro: 1.815 ± 1.212
1.815HisGln: 1.815 ± 1.533
0.907HisArg: 0.907 ± 0.606
1.815HisSer: 1.815 ± 1.533
7.26HisThr: 7.26 ± 0.643
0.907HisVal: 0.907 ± 0.606
0.907HisTrp: 0.907 ± 0.606
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
7.26IleAla: 7.26 ± 2.015
0.907IleCys: 0.907 ± 0.766
2.722IleAsp: 2.722 ± 0.445
1.815IleGlu: 1.815 ± 1.533
2.722IlePhe: 2.722 ± 0.445
3.63IleGly: 3.63 ± 0.321
0.0IleHis: 0.0 ± 0.0
6.352IleIle: 6.352 ± 1.496
2.722IleLys: 2.722 ± 1.817
5.445IleLeu: 5.445 ± 0.89
1.815IleMet: 1.815 ± 1.212
2.722IleAsn: 2.722 ± 0.927
5.445IlePro: 5.445 ± 3.226
0.0IleGln: 0.0 ± 0.0
6.352IleArg: 6.352 ± 0.124
1.815IleSer: 1.815 ± 0.161
6.352IleThr: 6.352 ± 2.868
5.445IleVal: 5.445 ± 2.263
0.907IleTrp: 0.907 ± 0.606
0.907IleTyr: 0.907 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
0.907LysAla: 0.907 ± 0.606
0.907LysCys: 0.907 ± 0.606
1.815LysAsp: 1.815 ± 1.212
0.0LysGlu: 0.0 ± 0.0
0.907LysPhe: 0.907 ± 0.606
0.0LysGly: 0.0 ± 0.0
1.815LysHis: 1.815 ± 1.212
0.907LysIle: 0.907 ± 0.606
0.907LysLys: 0.907 ± 0.606
1.815LysLeu: 1.815 ± 1.212
0.907LysMet: 0.907 ± 0.606
0.0LysAsn: 0.0 ± 0.0
0.907LysPro: 0.907 ± 0.606
0.0LysGln: 0.0 ± 0.0
2.722LysArg: 2.722 ± 0.445
4.537LysSer: 4.537 ± 1.657
3.63LysThr: 3.63 ± 1.051
0.907LysVal: 0.907 ± 0.606
0.907LysTrp: 0.907 ± 0.606
0.907LysTyr: 0.907 ± 0.766
0.0LysXaa: 0.0 ± 0.0
Leu
5.445LeuAla: 5.445 ± 0.482
0.907LeuCys: 0.907 ± 0.766
5.445LeuAsp: 5.445 ± 2.263
7.26LeuGlu: 7.26 ± 2.102
5.445LeuPhe: 5.445 ± 2.263
4.537LeuGly: 4.537 ± 1.088
2.722LeuHis: 2.722 ± 0.445
2.722LeuIle: 2.722 ± 0.445
2.722LeuLys: 2.722 ± 0.927
9.074LeuLeu: 9.074 ± 0.803
0.907LeuMet: 0.907 ± 0.606
3.63LeuAsn: 3.63 ± 1.051
4.537LeuPro: 4.537 ± 0.285
3.63LeuGln: 3.63 ± 1.694
6.352LeuArg: 6.352 ± 1.248
1.815LeuSer: 1.815 ± 0.161
8.167LeuThr: 8.167 ± 1.336
1.815LeuVal: 1.815 ± 0.161
5.445LeuTrp: 5.445 ± 0.89
4.537LeuTyr: 4.537 ± 2.46
0.0LeuXaa: 0.0 ± 0.0
Met
1.815MetAla: 1.815 ± 1.212
0.0MetCys: 0.0 ± 0.0
0.907MetAsp: 0.907 ± 0.606
0.907MetGlu: 0.907 ± 0.766
1.815MetPhe: 1.815 ± 0.161
0.907MetGly: 0.907 ± 0.766
0.907MetHis: 0.907 ± 0.606
1.815MetIle: 1.815 ± 0.161
0.0MetLys: 0.0 ± 0.0
3.63MetLeu: 3.63 ± 2.423
1.815MetMet: 1.815 ± 1.533
0.907MetAsn: 0.907 ± 0.766
1.815MetPro: 1.815 ± 1.212
0.907MetGln: 0.907 ± 0.766
0.907MetArg: 0.907 ± 0.606
0.907MetSer: 0.907 ± 0.606
0.907MetThr: 0.907 ± 0.766
1.815MetVal: 1.815 ± 1.533
0.0MetTrp: 0.0 ± 0.0
2.722MetTyr: 2.722 ± 0.445
0.0MetXaa: 0.0 ± 0.0
Asn
3.63AsnAla: 3.63 ± 1.051
0.907AsnCys: 0.907 ± 0.606
0.907AsnAsp: 0.907 ± 0.606
0.907AsnGlu: 0.907 ± 0.606
3.63AsnPhe: 3.63 ± 0.321
5.445AsnGly: 5.445 ± 0.482
2.722AsnHis: 2.722 ± 1.817
4.537AsnIle: 4.537 ± 3.832
0.907AsnLys: 0.907 ± 0.606
2.722AsnLeu: 2.722 ± 0.445
0.907AsnMet: 0.907 ± 0.766
1.815AsnAsn: 1.815 ± 0.161
3.63AsnPro: 3.63 ± 0.321
4.537AsnGln: 4.537 ± 1.088
4.537AsnArg: 4.537 ± 1.657
1.815AsnSer: 1.815 ± 0.161
3.63AsnThr: 3.63 ± 3.066
6.352AsnVal: 6.352 ± 1.248
0.0AsnTrp: 0.0 ± 0.0
3.63AsnTyr: 3.63 ± 1.051
0.0AsnXaa: 0.0 ± 0.0
Pro
10.889ProAla: 10.889 ± 6.453
0.907ProCys: 0.907 ± 0.606
2.722ProAsp: 2.722 ± 0.445
2.722ProGlu: 2.722 ± 0.445
6.352ProPhe: 6.352 ± 1.248
3.63ProGly: 3.63 ± 0.321
2.722ProHis: 2.722 ± 2.299
3.63ProIle: 3.63 ± 1.694
0.907ProLys: 0.907 ± 0.606
3.63ProLeu: 3.63 ± 0.321
2.722ProMet: 2.722 ± 0.445
7.26ProAsn: 7.26 ± 0.643
4.537ProPro: 4.537 ± 1.657
1.815ProGln: 1.815 ± 0.161
2.722ProArg: 2.722 ± 0.445
4.537ProSer: 4.537 ± 0.285
5.445ProThr: 5.445 ± 0.89
0.907ProVal: 0.907 ± 0.766
0.907ProTrp: 0.907 ± 0.606
1.815ProTyr: 1.815 ± 1.212
0.0ProXaa: 0.0 ± 0.0
Gln
4.537GlnAla: 4.537 ± 1.088
0.907GlnCys: 0.907 ± 0.606
0.907GlnAsp: 0.907 ± 0.606
0.0GlnGlu: 0.0 ± 0.0
1.815GlnPhe: 1.815 ± 0.161
3.63GlnGly: 3.63 ± 0.321
1.815GlnHis: 1.815 ± 1.533
0.907GlnIle: 0.907 ± 0.766
0.907GlnLys: 0.907 ± 0.766
7.26GlnLeu: 7.26 ± 3.387
0.907GlnMet: 0.907 ± 0.766
1.815GlnAsn: 1.815 ± 0.161
0.907GlnPro: 0.907 ± 0.766
0.0GlnGln: 0.0 ± 0.0
1.815GlnArg: 1.815 ± 0.161
0.907GlnSer: 0.907 ± 0.766
1.815GlnThr: 1.815 ± 1.533
0.0GlnVal: 0.0 ± 0.0
0.907GlnTrp: 0.907 ± 0.606
1.815GlnTyr: 1.815 ± 1.533
0.0GlnXaa: 0.0 ± 0.0
Arg
2.722ArgAla: 2.722 ± 0.445
0.0ArgCys: 0.0 ± 0.0
3.63ArgAsp: 3.63 ± 1.051
0.907ArgGlu: 0.907 ± 0.766
5.445ArgPhe: 5.445 ± 1.854
0.0ArgGly: 0.0 ± 0.0
3.63ArgHis: 3.63 ± 1.051
4.537ArgIle: 4.537 ± 0.285
2.722ArgLys: 2.722 ± 0.445
3.63ArgLeu: 3.63 ± 2.423
2.722ArgMet: 2.722 ± 0.445
3.63ArgAsn: 3.63 ± 1.051
2.722ArgPro: 2.722 ± 1.817
0.0ArgGln: 0.0 ± 0.0
6.352ArgArg: 6.352 ± 1.496
5.445ArgSer: 5.445 ± 0.482
7.26ArgThr: 7.26 ± 0.643
3.63ArgVal: 3.63 ± 0.321
1.815ArgTrp: 1.815 ± 0.161
1.815ArgTyr: 1.815 ± 0.161
0.0ArgXaa: 0.0 ± 0.0
Ser
1.815SerAla: 1.815 ± 0.161
0.907SerCys: 0.907 ± 0.606
1.815SerAsp: 1.815 ± 0.161
2.722SerGlu: 2.722 ± 1.817
4.537SerPhe: 4.537 ± 0.285
3.63SerGly: 3.63 ± 1.694
2.722SerHis: 2.722 ± 0.927
4.537SerIle: 4.537 ± 0.285
0.907SerLys: 0.907 ± 0.606
4.537SerLeu: 4.537 ± 2.46
0.907SerMet: 0.907 ± 0.766
1.815SerAsn: 1.815 ± 0.161
1.815SerPro: 1.815 ± 0.161
3.63SerGln: 3.63 ± 3.066
2.722SerArg: 2.722 ± 0.445
1.815SerSer: 1.815 ± 1.533
3.63SerThr: 3.63 ± 1.051
1.815SerVal: 1.815 ± 1.533
1.815SerTrp: 1.815 ± 1.212
1.815SerTyr: 1.815 ± 0.161
0.0SerXaa: 0.0 ± 0.0
Thr
4.537ThrAla: 4.537 ± 2.46
0.907ThrCys: 0.907 ± 0.606
5.445ThrAsp: 5.445 ± 0.482
1.815ThrGlu: 1.815 ± 0.161
4.537ThrPhe: 4.537 ± 1.657
9.074ThrGly: 9.074 ± 4.92
2.722ThrHis: 2.722 ± 1.817
3.63ThrIle: 3.63 ± 2.423
2.722ThrLys: 2.722 ± 1.817
5.445ThrLeu: 5.445 ± 2.263
4.537ThrMet: 4.537 ± 1.657
4.537ThrAsn: 4.537 ± 1.088
10.889ThrPro: 10.889 ± 3.708
3.63ThrGln: 3.63 ± 0.321
4.537ThrArg: 4.537 ± 1.088
2.722ThrSer: 2.722 ± 2.299
3.63ThrThr: 3.63 ± 1.694
0.907ThrVal: 0.907 ± 0.606
1.815ThrTrp: 1.815 ± 0.161
2.722ThrTyr: 2.722 ± 0.927
0.0ThrXaa: 0.0 ± 0.0
Val
1.815ValAla: 1.815 ± 0.161
0.0ValCys: 0.0 ± 0.0
0.907ValAsp: 0.907 ± 0.766
2.722ValGlu: 2.722 ± 1.817
0.0ValPhe: 0.0 ± 0.0
0.907ValGly: 0.907 ± 0.766
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
3.63ValLys: 3.63 ± 2.423
4.537ValLeu: 4.537 ± 1.657
1.815ValMet: 1.815 ± 1.533
6.352ValAsn: 6.352 ± 1.248
7.26ValPro: 7.26 ± 0.643
0.907ValGln: 0.907 ± 0.606
1.815ValArg: 1.815 ± 0.161
2.722ValSer: 2.722 ± 2.299
1.815ValThr: 1.815 ± 1.533
0.0ValVal: 0.0 ± 0.0
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.907TrpAla: 0.907 ± 0.766
0.0TrpCys: 0.0 ± 0.0
0.907TrpAsp: 0.907 ± 0.766
0.907TrpGlu: 0.907 ± 0.606
2.722TrpPhe: 2.722 ± 0.445
1.815TrpGly: 1.815 ± 1.212
0.907TrpHis: 0.907 ± 0.606
1.815TrpIle: 1.815 ± 0.161
0.0TrpLys: 0.0 ± 0.0
2.722TrpLeu: 2.722 ± 0.927
0.0TrpMet: 0.0 ± 0.0
3.63TrpAsn: 3.63 ± 0.321
0.907TrpPro: 0.907 ± 0.606
0.0TrpGln: 0.0 ± 0.0
0.907TrpArg: 0.907 ± 0.766
0.907TrpSer: 0.907 ± 0.606
1.815TrpThr: 1.815 ± 1.212
1.815TrpVal: 1.815 ± 1.212
0.0TrpTrp: 0.0 ± 0.0
1.815TrpTyr: 1.815 ± 0.161
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.537TyrAla: 4.537 ± 2.46
0.907TyrCys: 0.907 ± 0.766
0.0TyrAsp: 0.0 ± 0.0
0.907TyrGlu: 0.907 ± 0.606
3.63TyrPhe: 3.63 ± 2.423
0.907TyrGly: 0.907 ± 0.606
1.815TyrHis: 1.815 ± 0.161
1.815TyrIle: 1.815 ± 0.161
0.907TyrLys: 0.907 ± 0.606
5.445TyrLeu: 5.445 ± 2.263
0.0TyrMet: 0.0 ± 0.0
2.722TyrAsn: 2.722 ± 1.817
3.63TyrPro: 3.63 ± 1.694
0.907TyrGln: 0.907 ± 0.606
4.537TyrArg: 4.537 ± 1.657
0.0TyrSer: 0.0 ± 0.0
4.537TyrThr: 4.537 ± 0.285
1.815TyrVal: 1.815 ± 0.161
2.722TyrTrp: 2.722 ± 0.927
2.722TyrTyr: 2.722 ± 0.445
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1103 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski