Amino acid dipepetide frequency for Circo-like virus-Brazil hs1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
0.0AlaAsp: 0.0 ± 0.0
2.094AlaGlu: 2.094 ± 0.899
2.094AlaPhe: 2.094 ± 1.059
1.047AlaGly: 1.047 ± 0.882
1.047AlaHis: 1.047 ± 1.041
1.047AlaIle: 1.047 ± 1.041
3.141AlaLys: 3.141 ± 0.809
2.094AlaLeu: 2.094 ± 1.002
2.094AlaMet: 2.094 ± 0.899
2.094AlaAsn: 2.094 ± 1.776
1.047AlaPro: 1.047 ± 0.882
0.0AlaGln: 0.0 ± 0.0
3.141AlaArg: 3.141 ± 1.819
2.094AlaSer: 2.094 ± 2.082
3.141AlaThr: 3.141 ± 1.906
1.047AlaVal: 1.047 ± 0.882
0.0AlaTrp: 0.0 ± 0.0
3.141AlaTyr: 3.141 ± 0.809
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.047CysAsp: 1.047 ± 0.888
0.0CysGlu: 0.0 ± 0.0
1.047CysPhe: 1.047 ± 0.882
3.141CysGly: 3.141 ± 1.649
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.047CysLeu: 1.047 ± 0.882
1.047CysMet: 1.047 ± 0.882
0.0CysAsn: 0.0 ± 0.0
1.047CysPro: 1.047 ± 0.882
1.047CysGln: 1.047 ± 0.882
1.047CysArg: 1.047 ± 0.882
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.141AspAla: 3.141 ± 1.685
0.0AspCys: 0.0 ± 0.0
4.188AspAsp: 4.188 ± 2.423
4.188AspGlu: 4.188 ± 1.221
3.141AspPhe: 3.141 ± 2.647
6.283AspGly: 6.283 ± 0.692
0.0AspHis: 0.0 ± 0.0
4.188AspIle: 4.188 ± 1.682
0.0AspLys: 0.0 ± 0.0
6.283AspLeu: 6.283 ± 2.879
0.0AspMet: 0.0 ± 0.0
1.047AspAsn: 1.047 ± 0.888
0.0AspPro: 0.0 ± 0.0
5.236AspGln: 5.236 ± 1.993
5.236AspArg: 5.236 ± 1.663
2.094AspSer: 2.094 ± 1.765
5.236AspThr: 5.236 ± 2.098
3.141AspVal: 3.141 ± 0.864
3.141AspTrp: 3.141 ± 0.864
6.283AspTyr: 6.283 ± 1.221
0.0AspXaa: 0.0 ± 0.0
Glu
3.141GluAla: 3.141 ± 0.913
1.047GluCys: 1.047 ± 0.882
4.188GluAsp: 4.188 ± 2.003
9.424GluGlu: 9.424 ± 3.558
4.188GluPhe: 4.188 ± 1.462
2.094GluGly: 2.094 ± 1.765
1.047GluHis: 1.047 ± 0.852
2.094GluIle: 2.094 ± 1.059
7.33GluLys: 7.33 ± 2.22
16.754GluLeu: 16.754 ± 3.653
1.047GluMet: 1.047 ± 0.852
4.188GluAsn: 4.188 ± 1.636
2.094GluPro: 2.094 ± 1.765
2.094GluGln: 2.094 ± 1.704
3.141GluArg: 3.141 ± 1.649
6.283GluSer: 6.283 ± 1.38
5.236GluThr: 5.236 ± 2.098
1.047GluVal: 1.047 ± 1.041
4.188GluTrp: 4.188 ± 2.496
5.236GluTyr: 5.236 ± 3.195
0.0GluXaa: 0.0 ± 0.0
Phe
1.047PheAla: 1.047 ± 0.882
0.0PheCys: 0.0 ± 0.0
4.188PheAsp: 4.188 ± 1.35
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
3.141PheGly: 3.141 ± 0.864
0.0PheHis: 0.0 ± 0.0
4.188PheIle: 4.188 ± 1.412
7.33PheLys: 7.33 ± 2.942
3.141PheLeu: 3.141 ± 1.801
1.047PheMet: 1.047 ± 1.041
3.141PheAsn: 3.141 ± 1.544
0.0PhePro: 0.0 ± 0.0
2.094PheGln: 2.094 ± 1.108
1.047PheArg: 1.047 ± 0.882
1.047PheSer: 1.047 ± 0.882
3.141PheThr: 3.141 ± 1.544
1.047PheVal: 1.047 ± 0.882
1.047PheTrp: 1.047 ± 0.882
2.094PheTyr: 2.094 ± 1.059
0.0PheXaa: 0.0 ± 0.0
Gly
1.047GlyAla: 1.047 ± 0.882
0.0GlyCys: 0.0 ± 0.0
2.094GlyAsp: 2.094 ± 0.899
5.236GlyGlu: 5.236 ± 2.14
3.141GlyPhe: 3.141 ± 0.864
2.094GlyGly: 2.094 ± 1.002
0.0GlyHis: 0.0 ± 0.0
3.141GlyIle: 3.141 ± 1.544
4.188GlyLys: 4.188 ± 1.462
3.141GlyLeu: 3.141 ± 0.864
1.047GlyMet: 1.047 ± 0.852
1.047GlyAsn: 1.047 ± 0.888
1.047GlyPro: 1.047 ± 0.882
1.047GlyGln: 1.047 ± 0.882
5.236GlyArg: 5.236 ± 1.971
4.188GlySer: 4.188 ± 1.438
4.188GlyThr: 4.188 ± 1.35
4.188GlyVal: 4.188 ± 1.35
4.188GlyTrp: 4.188 ± 2.883
4.188GlyTyr: 4.188 ± 1.798
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.047HisIle: 1.047 ± 0.882
0.0HisLys: 0.0 ± 0.0
3.141HisLeu: 3.141 ± 1.637
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.047HisArg: 1.047 ± 0.882
2.094HisSer: 2.094 ± 0.899
1.047HisThr: 1.047 ± 0.852
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.094HisTyr: 2.094 ± 1.172
0.0HisXaa: 0.0 ± 0.0
Ile
3.141IleAla: 3.141 ± 1.906
1.047IleCys: 1.047 ± 0.882
5.236IleAsp: 5.236 ± 1.785
7.33IleGlu: 7.33 ± 0.861
2.094IlePhe: 2.094 ± 1.172
2.094IleGly: 2.094 ± 1.704
0.0IleHis: 0.0 ± 0.0
5.236IleIle: 5.236 ± 1.971
7.33IleLys: 7.33 ± 2.358
2.094IleLeu: 2.094 ± 1.172
1.047IleMet: 1.047 ± 1.041
1.047IleAsn: 1.047 ± 0.888
3.141IlePro: 3.141 ± 1.801
1.047IleGln: 1.047 ± 0.882
1.047IleArg: 1.047 ± 0.882
3.141IleSer: 3.141 ± 0.809
5.236IleThr: 5.236 ± 1.781
3.141IleVal: 3.141 ± 0.913
2.094IleTrp: 2.094 ± 1.002
4.188IleTyr: 4.188 ± 1.636
0.0IleXaa: 0.0 ± 0.0
Lys
4.188LysAla: 4.188 ± 1.633
1.047LysCys: 1.047 ± 0.882
6.283LysAsp: 6.283 ± 3.128
7.33LysGlu: 7.33 ± 2.875
3.141LysPhe: 3.141 ± 1.801
6.283LysGly: 6.283 ± 2.339
2.094LysHis: 2.094 ± 1.002
5.236LysIle: 5.236 ± 2.644
14.66LysLys: 14.66 ± 5.079
4.188LysLeu: 4.188 ± 2.345
1.047LysMet: 1.047 ± 1.041
6.283LysAsn: 6.283 ± 2.616
2.094LysPro: 2.094 ± 1.002
2.094LysGln: 2.094 ± 1.776
7.33LysArg: 7.33 ± 0.753
3.141LysSer: 3.141 ± 0.913
5.236LysThr: 5.236 ± 1.811
4.188LysVal: 4.188 ± 1.328
1.047LysTrp: 1.047 ± 1.041
8.377LysTyr: 8.377 ± 2.545
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.047LeuCys: 1.047 ± 1.041
8.377LeuAsp: 8.377 ± 2.443
7.33LeuGlu: 7.33 ± 1.407
1.047LeuPhe: 1.047 ± 0.882
3.141LeuGly: 3.141 ± 1.685
1.047LeuHis: 1.047 ± 0.882
6.283LeuIle: 6.283 ± 1.392
5.236LeuLys: 5.236 ± 3.15
5.236LeuLeu: 5.236 ± 2.379
4.188LeuMet: 4.188 ± 1.128
3.141LeuAsn: 3.141 ± 0.913
3.141LeuPro: 3.141 ± 1.819
3.141LeuGln: 3.141 ± 1.819
4.188LeuArg: 4.188 ± 1.389
5.236LeuSer: 5.236 ± 1.993
2.094LeuThr: 2.094 ± 1.704
11.518LeuVal: 11.518 ± 4.507
0.0LeuTrp: 0.0 ± 0.0
2.094LeuTyr: 2.094 ± 1.172
0.0LeuXaa: 0.0 ± 0.0
Met
2.094MetAla: 2.094 ± 1.172
0.0MetCys: 0.0 ± 0.0
2.094MetAsp: 2.094 ± 1.704
3.141MetGlu: 3.141 ± 1.685
0.0MetPhe: 0.0 ± 0.0
2.094MetGly: 2.094 ± 1.059
1.047MetHis: 1.047 ± 0.852
2.094MetIle: 2.094 ± 1.108
1.047MetLys: 1.047 ± 0.888
0.0MetLeu: 0.0 ± 0.0
1.047MetMet: 1.047 ± 0.852
1.047MetAsn: 1.047 ± 0.852
1.047MetPro: 1.047 ± 1.041
0.0MetGln: 0.0 ± 0.0
2.094MetArg: 2.094 ± 1.138
3.141MetSer: 3.141 ± 0.809
1.047MetThr: 1.047 ± 0.852
4.188MetVal: 4.188 ± 0.281
1.047MetTrp: 1.047 ± 0.888
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.094AsnAla: 2.094 ± 1.172
0.0AsnCys: 0.0 ± 0.0
2.094AsnAsp: 2.094 ± 1.776
2.094AsnGlu: 2.094 ± 1.776
1.047AsnPhe: 1.047 ± 0.882
5.236AsnGly: 5.236 ± 1.647
0.0AsnHis: 0.0 ± 0.0
3.141AsnIle: 3.141 ± 1.554
3.141AsnLys: 3.141 ± 1.906
8.377AsnLeu: 8.377 ± 3.179
2.094AsnMet: 2.094 ± 1.108
0.0AsnAsn: 0.0 ± 0.0
1.047AsnPro: 1.047 ± 0.888
1.047AsnGln: 1.047 ± 0.852
6.283AsnArg: 6.283 ± 2.127
3.141AsnSer: 3.141 ± 0.913
6.283AsnThr: 6.283 ± 2.945
5.236AsnVal: 5.236 ± 0.977
1.047AsnTrp: 1.047 ± 0.888
3.141AsnTyr: 3.141 ± 0.913
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
4.188ProAsp: 4.188 ± 1.633
2.094ProGlu: 2.094 ± 1.002
1.047ProPhe: 1.047 ± 0.888
2.094ProGly: 2.094 ± 0.899
1.047ProHis: 1.047 ± 0.888
2.094ProIle: 2.094 ± 0.899
3.141ProLys: 3.141 ± 1.801
2.094ProLeu: 2.094 ± 1.002
1.047ProMet: 1.047 ± 0.793
3.141ProAsn: 3.141 ± 0.809
1.047ProPro: 1.047 ± 1.041
0.0ProGln: 0.0 ± 0.0
2.094ProArg: 2.094 ± 0.899
0.0ProSer: 0.0 ± 0.0
3.141ProThr: 3.141 ± 1.14
2.094ProVal: 2.094 ± 1.138
0.0ProTrp: 0.0 ± 0.0
1.047ProTyr: 1.047 ± 1.041
0.0ProXaa: 0.0 ± 0.0
Gln
1.047GlnAla: 1.047 ± 0.882
0.0GlnCys: 0.0 ± 0.0
1.047GlnAsp: 1.047 ± 0.888
6.283GlnGlu: 6.283 ± 3.532
0.0GlnPhe: 0.0 ± 0.0
1.047GlnGly: 1.047 ± 0.882
0.0GlnHis: 0.0 ± 0.0
2.094GlnIle: 2.094 ± 1.776
6.283GlnLys: 6.283 ± 2.393
0.0GlnLeu: 0.0 ± 0.0
2.094GlnMet: 2.094 ± 1.534
3.141GlnAsn: 3.141 ± 0.864
2.094GlnPro: 2.094 ± 1.059
0.0GlnGln: 0.0 ± 0.0
2.094GlnArg: 2.094 ± 0.899
0.0GlnSer: 0.0 ± 0.0
3.141GlnThr: 3.141 ± 0.864
0.0GlnVal: 0.0 ± 0.0
2.094GlnTrp: 2.094 ± 1.108
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.094ArgAla: 2.094 ± 1.765
2.094ArgCys: 2.094 ± 1.765
4.188ArgAsp: 4.188 ± 1.221
5.236ArgGlu: 5.236 ± 3.253
4.188ArgPhe: 4.188 ± 2.349
2.094ArgGly: 2.094 ± 0.899
0.0ArgHis: 0.0 ± 0.0
2.094ArgIle: 2.094 ± 0.899
9.424ArgLys: 9.424 ± 1.954
7.33ArgLeu: 7.33 ± 2.762
1.047ArgMet: 1.047 ± 0.882
5.236ArgAsn: 5.236 ± 2.15
2.094ArgPro: 2.094 ± 1.108
2.094ArgGln: 2.094 ± 0.899
5.236ArgArg: 5.236 ± 2.14
3.141ArgSer: 3.141 ± 0.864
3.141ArgThr: 3.141 ± 1.14
1.047ArgVal: 1.047 ± 0.882
3.141ArgTrp: 3.141 ± 1.72
2.094ArgTyr: 2.094 ± 1.765
0.0ArgXaa: 0.0 ± 0.0
Ser
3.141SerAla: 3.141 ± 1.801
0.0SerCys: 0.0 ± 0.0
3.141SerAsp: 3.141 ± 0.913
5.236SerGlu: 5.236 ± 1.609
3.141SerPhe: 3.141 ± 2.032
2.094SerGly: 2.094 ± 0.899
1.047SerHis: 1.047 ± 0.888
1.047SerIle: 1.047 ± 0.888
6.283SerLys: 6.283 ± 1.817
6.283SerLeu: 6.283 ± 3.128
2.094SerMet: 2.094 ± 1.704
4.188SerAsn: 4.188 ± 2.119
0.0SerPro: 0.0 ± 0.0
2.094SerGln: 2.094 ± 1.002
3.141SerArg: 3.141 ± 1.649
1.047SerSer: 1.047 ± 1.041
4.188SerThr: 4.188 ± 1.462
1.047SerVal: 1.047 ± 0.882
1.047SerTrp: 1.047 ± 1.041
2.094SerTyr: 2.094 ± 0.899
0.0SerXaa: 0.0 ± 0.0
Thr
3.141ThrAla: 3.141 ± 2.664
0.0ThrCys: 0.0 ± 0.0
2.094ThrAsp: 2.094 ± 1.172
8.377ThrGlu: 8.377 ± 1.872
0.0ThrPhe: 0.0 ± 0.0
3.141ThrGly: 3.141 ± 1.685
1.047ThrHis: 1.047 ± 0.882
5.236ThrIle: 5.236 ± 2.644
4.188ThrLys: 4.188 ± 1.462
4.188ThrLeu: 4.188 ± 1.636
2.094ThrMet: 2.094 ± 1.776
3.141ThrAsn: 3.141 ± 1.72
4.188ThrPro: 4.188 ± 3.008
3.141ThrGln: 3.141 ± 2.556
1.047ThrArg: 1.047 ± 0.882
7.33ThrSer: 7.33 ± 1.617
3.141ThrThr: 3.141 ± 1.14
3.141ThrVal: 3.141 ± 1.766
1.047ThrTrp: 1.047 ± 0.852
3.141ThrTyr: 3.141 ± 0.809
0.0ThrXaa: 0.0 ± 0.0
Val
1.047ValAla: 1.047 ± 1.041
0.0ValCys: 0.0 ± 0.0
4.188ValAsp: 4.188 ± 1.636
5.236ValGlu: 5.236 ± 1.971
3.141ValPhe: 3.141 ± 0.913
4.188ValGly: 4.188 ± 1.438
1.047ValHis: 1.047 ± 0.882
3.141ValIle: 3.141 ± 1.801
3.141ValLys: 3.141 ± 1.14
1.047ValLeu: 1.047 ± 0.888
2.094ValMet: 2.094 ± 1.172
7.33ValAsn: 7.33 ± 3.12
4.188ValPro: 4.188 ± 1.438
3.141ValGln: 3.141 ± 1.685
7.33ValArg: 7.33 ± 0.861
2.094ValSer: 2.094 ± 1.108
0.0ValThr: 0.0 ± 0.0
2.094ValVal: 2.094 ± 1.765
1.047ValTrp: 1.047 ± 0.852
2.094ValTyr: 2.094 ± 1.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
2.094TrpCys: 2.094 ± 1.765
3.141TrpAsp: 3.141 ± 1.906
1.047TrpGlu: 1.047 ± 0.852
1.047TrpPhe: 1.047 ± 0.882
1.047TrpGly: 1.047 ± 0.882
0.0TrpHis: 0.0 ± 0.0
2.094TrpIle: 2.094 ± 1.002
4.188TrpLys: 4.188 ± 1.636
1.047TrpLeu: 1.047 ± 0.882
0.0TrpMet: 0.0 ± 0.0
1.047TrpAsn: 1.047 ± 0.852
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
2.094TrpSer: 2.094 ± 1.138
1.047TrpThr: 1.047 ± 0.888
5.236TrpVal: 5.236 ± 2.15
2.094TrpTrp: 2.094 ± 1.059
2.094TrpTyr: 2.094 ± 1.002
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
2.094TyrCys: 2.094 ± 0.899
1.047TyrAsp: 1.047 ± 0.882
4.188TyrGlu: 4.188 ± 2.423
5.236TyrPhe: 5.236 ± 0.95
2.094TyrGly: 2.094 ± 0.899
0.0TyrHis: 0.0 ± 0.0
5.236TyrIle: 5.236 ± 1.256
5.236TyrLys: 5.236 ± 1.865
1.047TyrLeu: 1.047 ± 0.888
1.047TyrMet: 1.047 ± 0.871
6.283TyrAsn: 6.283 ± 1.519
2.094TyrPro: 2.094 ± 1.172
3.141TyrGln: 3.141 ± 2.664
5.236TyrArg: 5.236 ± 1.971
1.047TyrSer: 1.047 ± 0.852
3.141TyrThr: 3.141 ± 2.032
4.188TyrVal: 4.188 ± 0.281
1.047TyrTrp: 1.047 ± 0.882
2.094TyrTyr: 2.094 ± 1.172
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (956 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski