Amino acid dipepetide frequency for Miniopterus schreibersii polyomavirus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.339AlaAla: 5.339 ± 2.421
1.068AlaCys: 1.068 ± 0.449
2.67AlaAsp: 2.67 ± 1.308
6.407AlaGlu: 6.407 ± 3.175
3.737AlaPhe: 3.737 ± 1.567
3.203AlaGly: 3.203 ± 1.267
2.136AlaHis: 2.136 ± 0.818
3.203AlaIle: 3.203 ± 1.586
5.873AlaLys: 5.873 ± 1.732
6.941AlaLeu: 6.941 ± 2.877
1.068AlaMet: 1.068 ± 1.189
1.068AlaAsn: 1.068 ± 1.024
1.068AlaPro: 1.068 ± 0.449
4.271AlaGln: 4.271 ± 2.152
2.136AlaArg: 2.136 ± 1.141
5.873AlaSer: 5.873 ± 1.6
2.67AlaThr: 2.67 ± 0.589
4.271AlaVal: 4.271 ± 1.158
1.068AlaTrp: 1.068 ± 0.756
1.602AlaTyr: 1.602 ± 0.819
0.0AlaXaa: 0.0 ± 0.0
Cys
3.203CysAla: 3.203 ± 0.667
0.0CysCys: 0.0 ± 0.0
1.068CysAsp: 1.068 ± 0.756
1.068CysGlu: 1.068 ± 0.756
1.602CysPhe: 1.602 ± 0.819
0.0CysGly: 0.0 ± 0.0
0.534CysHis: 0.534 ± 0.512
0.534CysIle: 0.534 ± 0.55
2.136CysLys: 2.136 ± 0.899
4.805CysLeu: 4.805 ± 2.794
0.534CysMet: 0.534 ± 0.55
2.136CysAsn: 2.136 ± 0.866
2.67CysPro: 2.67 ± 1.308
0.0CysGln: 0.0 ± 0.0
1.602CysArg: 1.602 ± 0.819
1.602CysSer: 1.602 ± 0.819
1.068CysThr: 1.068 ± 0.756
0.534CysVal: 0.534 ± 0.378
0.0CysTrp: 0.0 ± 0.0
0.534CysTyr: 0.534 ± 0.55
0.0CysXaa: 0.0 ± 0.0
Asp
1.602AspAla: 1.602 ± 0.759
0.534AspCys: 0.534 ± 0.55
1.068AspAsp: 1.068 ± 0.756
4.271AspGlu: 4.271 ± 0.785
2.136AspPhe: 2.136 ± 1.512
4.271AspGly: 4.271 ± 0.959
0.534AspHis: 0.534 ± 0.378
4.805AspIle: 4.805 ± 1.514
2.136AspLys: 2.136 ± 0.689
4.805AspLeu: 4.805 ± 1.309
0.534AspMet: 0.534 ± 0.512
0.534AspAsn: 0.534 ± 0.378
6.407AspPro: 6.407 ± 1.67
2.136AspGln: 2.136 ± 1.375
2.136AspArg: 2.136 ± 0.689
3.737AspSer: 3.737 ± 1.216
1.068AspThr: 1.068 ± 1.189
2.67AspVal: 2.67 ± 0.956
1.068AspTrp: 1.068 ± 0.935
0.534AspTyr: 0.534 ± 0.378
0.0AspXaa: 0.0 ± 0.0
Glu
6.941GluAla: 6.941 ± 3.708
0.534GluCys: 0.534 ± 0.55
3.203GluAsp: 3.203 ± 1.005
6.941GluGlu: 6.941 ± 1.566
1.602GluPhe: 1.602 ± 1.134
2.67GluGly: 2.67 ± 0.896
1.068GluHis: 1.068 ± 0.756
2.67GluIle: 2.67 ± 0.568
2.136GluLys: 2.136 ± 1.512
4.805GluLeu: 4.805 ± 0.847
1.602GluMet: 1.602 ± 0.73
1.602GluAsn: 1.602 ± 0.631
3.737GluPro: 3.737 ± 1.486
2.136GluGln: 2.136 ± 0.9
5.873GluArg: 5.873 ± 1.029
3.203GluSer: 3.203 ± 0.951
2.67GluThr: 2.67 ± 0.589
4.805GluVal: 4.805 ± 1.562
0.534GluTrp: 0.534 ± 0.512
2.67GluTyr: 2.67 ± 0.803
0.0GluXaa: 0.0 ± 0.0
Phe
4.271PheAla: 4.271 ± 1.244
3.203PheCys: 3.203 ± 0.954
3.737PheAsp: 3.737 ± 1.192
2.136PheGlu: 2.136 ± 1.132
0.0PhePhe: 0.0 ± 0.0
2.67PheGly: 2.67 ± 0.745
0.534PheHis: 0.534 ± 0.378
2.136PheIle: 2.136 ± 0.818
3.203PheLys: 3.203 ± 1.257
3.203PheLeu: 3.203 ± 1.617
0.534PheMet: 0.534 ± 0.378
1.602PheAsn: 1.602 ± 0.793
1.068PhePro: 1.068 ± 0.756
2.136PheGln: 2.136 ± 1.871
2.136PheArg: 2.136 ± 0.899
2.67PheSer: 2.67 ± 0.997
5.873PheThr: 5.873 ± 0.96
1.068PheVal: 1.068 ± 1.024
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.136GlyAla: 2.136 ± 0.697
1.602GlyCys: 1.602 ± 0.819
2.67GlyAsp: 2.67 ± 0.94
3.203GlyGlu: 3.203 ± 0.72
1.068GlyPhe: 1.068 ± 0.935
4.805GlyGly: 4.805 ± 1.287
0.0GlyHis: 0.0 ± 0.0
6.407GlyIle: 6.407 ± 2.826
2.136GlyLys: 2.136 ± 0.689
6.941GlyLeu: 6.941 ± 2.414
0.0GlyMet: 0.0 ± 0.0
1.068GlyAsn: 1.068 ± 0.935
3.737GlyPro: 3.737 ± 1.771
2.67GlyGln: 2.67 ± 1.056
2.67GlyArg: 2.67 ± 1.693
3.203GlySer: 3.203 ± 1.348
2.67GlyThr: 2.67 ± 0.931
6.941GlyVal: 6.941 ± 1.242
1.068GlyTrp: 1.068 ± 0.935
3.203GlyTyr: 3.203 ± 1.331
0.0GlyXaa: 0.0 ± 0.0
His
2.67HisAla: 2.67 ± 1.056
1.602HisCys: 1.602 ± 0.819
2.136HisAsp: 2.136 ± 1.871
0.0HisGlu: 0.0 ± 0.0
1.602HisPhe: 1.602 ± 1.047
0.0HisGly: 0.0 ± 0.0
0.534HisHis: 0.534 ± 0.378
0.534HisIle: 0.534 ± 0.512
0.0HisLys: 0.0 ± 0.0
1.602HisLeu: 1.602 ± 0.631
1.602HisMet: 1.602 ± 0.654
0.0HisAsn: 0.0 ± 0.0
1.068HisPro: 1.068 ± 0.586
4.271HisGln: 4.271 ± 3.011
0.534HisArg: 0.534 ± 0.378
1.068HisSer: 1.068 ± 0.756
0.534HisThr: 0.534 ± 0.512
2.67HisVal: 2.67 ± 0.997
0.0HisTrp: 0.0 ± 0.0
0.534HisTyr: 0.534 ± 0.378
0.0HisXaa: 0.0 ± 0.0
Ile
2.136IleAla: 2.136 ± 1.141
1.068IleCys: 1.068 ± 0.449
3.203IleAsp: 3.203 ± 0.707
2.67IleGlu: 2.67 ± 1.308
2.67IlePhe: 2.67 ± 0.721
1.602IleGly: 1.602 ± 0.967
1.068IleHis: 1.068 ± 0.935
2.136IleIle: 2.136 ± 0.9
1.602IleLys: 1.602 ± 0.91
5.339IleLeu: 5.339 ± 1.22
0.534IleMet: 0.534 ± 0.512
2.67IleAsn: 2.67 ± 1.392
2.67IlePro: 2.67 ± 0.845
1.602IleGln: 1.602 ± 0.967
3.203IleArg: 3.203 ± 0.538
5.873IleSer: 5.873 ± 3.923
1.602IleThr: 1.602 ± 1.126
3.203IleVal: 3.203 ± 0.667
0.534IleTrp: 0.534 ± 0.55
0.534IleTyr: 0.534 ± 0.595
0.0IleXaa: 0.0 ± 0.0
Lys
3.737LysAla: 3.737 ± 1.228
2.136LysCys: 2.136 ± 1.132
0.534LysAsp: 0.534 ± 0.378
3.737LysGlu: 3.737 ± 1.216
1.602LysPhe: 1.602 ± 0.793
2.67LysGly: 2.67 ± 0.721
1.602LysHis: 1.602 ± 0.809
2.136LysIle: 2.136 ± 0.899
3.737LysLys: 3.737 ± 1.152
4.271LysLeu: 4.271 ± 1.51
0.534LysMet: 0.534 ± 0.378
2.67LysAsn: 2.67 ± 1.056
2.136LysPro: 2.136 ± 0.699
4.805LysGln: 4.805 ± 1.746
4.271LysArg: 4.271 ± 1.12
2.67LysSer: 2.67 ± 1.061
4.271LysThr: 4.271 ± 1.12
3.203LysVal: 3.203 ± 0.667
0.534LysTrp: 0.534 ± 0.595
0.534LysTyr: 0.534 ± 0.512
0.0LysXaa: 0.0 ± 0.0
Leu
3.737LeuAla: 3.737 ± 1.285
2.136LeuCys: 2.136 ± 0.689
6.941LeuAsp: 6.941 ± 1.972
9.61LeuGlu: 9.61 ± 1.943
4.805LeuPhe: 4.805 ± 2.282
3.203LeuGly: 3.203 ± 1.587
6.407LeuHis: 6.407 ± 1.983
6.407LeuIle: 6.407 ± 2.724
6.407LeuLys: 6.407 ± 1.82
16.017LeuLeu: 16.017 ± 3.214
4.271LeuMet: 4.271 ± 1.484
3.737LeuAsn: 3.737 ± 1.226
5.339LeuPro: 5.339 ± 3.428
3.203LeuGln: 3.203 ± 1.348
7.475LeuArg: 7.475 ± 1.413
4.271LeuSer: 4.271 ± 2.723
3.203LeuThr: 3.203 ± 1.063
8.009LeuVal: 8.009 ± 1.988
2.136LeuTrp: 2.136 ± 1.599
3.737LeuTyr: 3.737 ± 0.578
0.0LeuXaa: 0.0 ± 0.0
Met
2.67MetAla: 2.67 ± 1.257
0.0MetCys: 0.0 ± 0.0
3.203MetAsp: 3.203 ± 1.189
0.0MetGlu: 0.0 ± 0.0
1.602MetPhe: 1.602 ± 0.967
2.136MetGly: 2.136 ± 0.679
0.0MetHis: 0.0 ± 0.0
0.534MetIle: 0.534 ± 0.695
0.534MetLys: 0.534 ± 0.595
3.737MetLeu: 3.737 ± 1.187
0.534MetMet: 0.534 ± 0.378
2.136MetAsn: 2.136 ± 1.11
1.068MetPro: 1.068 ± 0.449
0.0MetGln: 0.0 ± 0.0
1.602MetArg: 1.602 ± 0.819
1.068MetSer: 1.068 ± 0.716
2.67MetThr: 2.67 ± 0.745
1.068MetVal: 1.068 ± 0.771
1.602MetTrp: 1.602 ± 0.631
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.534AsnAla: 0.534 ± 0.378
1.602AsnCys: 1.602 ± 0.592
1.068AsnAsp: 1.068 ± 1.024
2.136AsnGlu: 2.136 ± 0.899
0.534AsnPhe: 0.534 ± 0.378
1.068AsnGly: 1.068 ± 0.756
1.068AsnHis: 1.068 ± 0.756
1.602AsnIle: 1.602 ± 0.793
2.67AsnLys: 2.67 ± 1.317
4.805AsnLeu: 4.805 ± 1.246
1.602AsnMet: 1.602 ± 0.793
0.0AsnAsn: 0.0 ± 0.0
3.203AsnPro: 3.203 ± 1.23
1.602AsnGln: 1.602 ± 0.819
2.67AsnArg: 2.67 ± 1.693
3.203AsnSer: 3.203 ± 1.005
1.068AsnThr: 1.068 ± 0.756
3.737AsnVal: 3.737 ± 0.557
0.534AsnTrp: 0.534 ± 0.512
0.534AsnTyr: 0.534 ± 0.512
0.0AsnXaa: 0.0 ± 0.0
Pro
2.136ProAla: 2.136 ± 1.232
1.068ProCys: 1.068 ± 0.756
4.271ProAsp: 4.271 ± 1.032
1.602ProGlu: 1.602 ± 0.809
1.602ProPhe: 1.602 ± 0.793
2.136ProGly: 2.136 ± 0.818
1.068ProHis: 1.068 ± 0.8
1.068ProIle: 1.068 ± 1.024
4.271ProLys: 4.271 ± 1.704
6.941ProLeu: 6.941 ± 1.822
1.602ProMet: 1.602 ± 1.166
1.602ProAsn: 1.602 ± 0.809
11.746ProPro: 11.746 ± 6.54
4.271ProGln: 4.271 ± 1.538
4.271ProArg: 4.271 ± 1.479
6.941ProSer: 6.941 ± 2.397
3.203ProThr: 3.203 ± 0.909
3.203ProVal: 3.203 ± 1.705
0.0ProTrp: 0.0 ± 0.0
1.068ProTyr: 1.068 ± 0.449
0.0ProXaa: 0.0 ± 0.0
Gln
8.542GlnAla: 8.542 ± 1.609
0.534GlnCys: 0.534 ± 0.378
3.203GlnAsp: 3.203 ± 1.665
1.068GlnGlu: 1.068 ± 0.586
3.737GlnPhe: 3.737 ± 1.643
4.805GlnGly: 4.805 ± 1.496
0.534GlnHis: 0.534 ± 0.55
3.203GlnIle: 3.203 ± 0.589
2.67GlnLys: 2.67 ± 2.025
8.009GlnLeu: 8.009 ± 2.553
1.068GlnMet: 1.068 ± 0.575
1.602GlnAsn: 1.602 ± 0.793
0.534GlnPro: 0.534 ± 0.512
0.0GlnGln: 0.0 ± 0.0
2.136GlnArg: 2.136 ± 0.858
2.136GlnSer: 2.136 ± 1.132
3.203GlnThr: 3.203 ± 0.667
2.136GlnVal: 2.136 ± 1.132
0.0GlnTrp: 0.0 ± 0.0
0.534GlnTyr: 0.534 ± 0.512
0.0GlnXaa: 0.0 ± 0.0
Arg
2.136ArgAla: 2.136 ± 1.141
0.534ArgCys: 0.534 ± 0.55
2.67ArgAsp: 2.67 ± 1.061
1.068ArgGlu: 1.068 ± 0.756
2.67ArgPhe: 2.67 ± 1.317
3.203ArgGly: 3.203 ± 1.01
0.534ArgHis: 0.534 ± 0.595
2.136ArgIle: 2.136 ± 0.697
5.339ArgLys: 5.339 ± 1.74
5.873ArgLeu: 5.873 ± 1.301
1.068ArgMet: 1.068 ± 1.024
1.068ArgAsn: 1.068 ± 0.449
2.136ArgPro: 2.136 ± 1.201
1.602ArgGln: 1.602 ± 0.738
3.203ArgArg: 3.203 ± 1.23
5.339ArgSer: 5.339 ± 2.18
2.136ArgThr: 2.136 ± 1.172
6.407ArgVal: 6.407 ± 1.983
2.136ArgTrp: 2.136 ± 1.871
3.203ArgTyr: 3.203 ± 1.286
0.0ArgXaa: 0.0 ± 0.0
Ser
5.339SerAla: 5.339 ± 1.059
3.737SerCys: 3.737 ± 1.226
2.136SerAsp: 2.136 ± 1.11
1.602SerGlu: 1.602 ± 0.631
5.873SerPhe: 5.873 ± 1.617
6.407SerGly: 6.407 ± 1.133
1.602SerHis: 1.602 ± 0.793
0.534SerIle: 0.534 ± 0.378
2.67SerLys: 2.67 ± 0.568
10.144SerLeu: 10.144 ± 1.521
2.67SerMet: 2.67 ± 1.554
2.67SerAsn: 2.67 ± 0.997
2.67SerPro: 2.67 ± 1.193
4.805SerGln: 4.805 ± 1.825
3.737SerArg: 3.737 ± 1.959
10.678SerSer: 10.678 ± 3.299
5.339SerThr: 5.339 ± 0.852
4.271SerVal: 4.271 ± 2.425
0.534SerTrp: 0.534 ± 0.378
1.602SerTyr: 1.602 ± 1.134
0.0SerXaa: 0.0 ± 0.0
Thr
3.203ThrAla: 3.203 ± 0.538
1.068ThrCys: 1.068 ± 0.449
1.068ThrAsp: 1.068 ± 0.449
3.203ThrGlu: 3.203 ± 1.149
1.602ThrPhe: 1.602 ± 0.819
4.271ThrGly: 4.271 ± 1.706
0.0ThrHis: 0.0 ± 0.0
2.67ThrIle: 2.67 ± 1.339
0.534ThrLys: 0.534 ± 0.378
6.407ThrLeu: 6.407 ± 2.414
3.203ThrMet: 3.203 ± 0.67
3.737ThrAsn: 3.737 ± 0.648
8.009ThrPro: 8.009 ± 1.131
2.67ThrGln: 2.67 ± 0.829
1.602ThrArg: 1.602 ± 0.809
3.203ThrSer: 3.203 ± 0.667
5.339ThrThr: 5.339 ± 1.984
2.67ThrVal: 2.67 ± 0.829
1.068ThrTrp: 1.068 ± 0.586
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.203ValAla: 3.203 ± 0.538
2.136ValCys: 2.136 ± 1.172
1.602ValAsp: 1.602 ± 0.809
7.475ValGlu: 7.475 ± 2.351
1.602ValPhe: 1.602 ± 0.809
4.805ValGly: 4.805 ± 3.0
2.67ValHis: 2.67 ± 0.931
1.602ValIle: 1.602 ± 0.592
2.136ValLys: 2.136 ± 0.689
2.67ValLeu: 2.67 ± 0.757
2.136ValMet: 2.136 ± 1.614
3.737ValAsn: 3.737 ± 1.566
2.67ValPro: 2.67 ± 1.308
5.339ValGln: 5.339 ± 2.274
3.203ValArg: 3.203 ± 1.381
8.009ValSer: 8.009 ± 1.224
5.873ValThr: 5.873 ± 1.6
2.67ValVal: 2.67 ± 0.757
0.534ValTrp: 0.534 ± 0.55
1.068ValTyr: 1.068 ± 0.449
0.0ValXaa: 0.0 ± 0.0
Trp
1.602TrpAla: 1.602 ± 0.819
1.068TrpCys: 1.068 ± 0.935
0.534TrpAsp: 0.534 ± 0.55
1.068TrpGlu: 1.068 ± 0.716
0.534TrpPhe: 0.534 ± 0.55
1.068TrpGly: 1.068 ± 0.716
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.534TrpLys: 0.534 ± 0.378
1.068TrpLeu: 1.068 ± 0.935
0.534TrpMet: 0.534 ± 0.595
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.068TrpGln: 1.068 ± 0.586
0.0TrpArg: 0.0 ± 0.0
1.068TrpSer: 1.068 ± 0.935
0.0TrpThr: 0.0 ± 0.0
1.602TrpVal: 1.602 ± 1.092
0.0TrpTrp: 0.0 ± 0.0
1.602TrpTyr: 1.602 ± 0.654
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.534TyrAla: 0.534 ± 0.378
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.136TyrGlu: 2.136 ± 0.697
1.602TyrPhe: 1.602 ± 0.654
3.203TyrGly: 3.203 ± 1.331
1.068TyrHis: 1.068 ± 0.449
1.602TyrIle: 1.602 ± 0.631
1.068TyrLys: 1.068 ± 0.756
2.67TyrLeu: 2.67 ± 1.121
0.0TyrMet: 0.0 ± 0.0
1.602TyrAsn: 1.602 ± 0.819
2.136TyrPro: 2.136 ± 1.232
1.602TyrGln: 1.602 ± 0.592
0.0TyrArg: 0.0 ± 0.0
3.203TyrSer: 3.203 ± 1.286
1.068TyrThr: 1.068 ± 0.756
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.136TyrTyr: 2.136 ± 0.939
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1874 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski