Amino acid dipepetide frequency for Campylobacter lanienae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.03AlaAla: 5.03 ± 0.15
0.787AlaCys: 0.787 ± 0.045
3.317AlaAsp: 3.317 ± 0.096
2.703AlaGlu: 2.703 ± 0.086
3.093AlaPhe: 3.093 ± 0.085
4.418AlaGly: 4.418 ± 0.125
1.264AlaHis: 1.264 ± 0.051
7.532AlaIle: 7.532 ± 0.143
7.724AlaLys: 7.724 ± 0.141
8.16AlaLeu: 8.16 ± 0.143
2.286AlaMet: 2.286 ± 0.084
4.928AlaAsn: 4.928 ± 0.111
1.958AlaPro: 1.958 ± 0.066
2.432AlaGln: 2.432 ± 0.069
2.824AlaArg: 2.824 ± 0.079
4.898AlaSer: 4.898 ± 0.099
3.791AlaThr: 3.791 ± 0.109
4.037AlaVal: 4.037 ± 0.103
0.47AlaTrp: 0.47 ± 0.034
2.502AlaTyr: 2.502 ± 0.064
0.0AlaXaa: 0.0 ± 0.0
Cys
0.878CysAla: 0.878 ± 0.043
0.097CysCys: 0.097 ± 0.018
1.031CysAsp: 1.031 ± 0.051
0.898CysGlu: 0.898 ± 0.049
0.5CysPhe: 0.5 ± 0.037
1.065CysGly: 1.065 ± 0.054
0.216CysHis: 0.216 ± 0.024
0.815CysIle: 0.815 ± 0.042
0.771CysLys: 0.771 ± 0.038
0.828CysLeu: 0.828 ± 0.047
0.231CysMet: 0.231 ± 0.024
0.468CysAsn: 0.468 ± 0.032
0.385CysPro: 0.385 ± 0.037
0.305CysGln: 0.305 ± 0.026
0.258CysArg: 0.258 ± 0.025
0.749CysSer: 0.749 ± 0.041
0.377CysThr: 0.377 ± 0.026
0.876CysVal: 0.876 ± 0.048
0.072CysTrp: 0.072 ± 0.015
0.366CysTyr: 0.366 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
3.654AspAla: 3.654 ± 0.091
0.544AspCys: 0.544 ± 0.038
3.34AspAsp: 3.34 ± 0.097
5.851AspGlu: 5.851 ± 0.138
2.908AspPhe: 2.908 ± 0.082
4.138AspGly: 4.138 ± 0.104
0.633AspHis: 0.633 ± 0.037
6.532AspIle: 6.532 ± 0.151
4.941AspLys: 4.941 ± 0.119
4.905AspLeu: 4.905 ± 0.113
1.63AspMet: 1.63 ± 0.06
2.993AspAsn: 2.993 ± 0.103
1.511AspPro: 1.511 ± 0.066
1.109AspGln: 1.109 ± 0.05
2.138AspArg: 2.138 ± 0.071
3.84AspSer: 3.84 ± 0.088
2.405AspThr: 2.405 ± 0.07
2.697AspVal: 2.697 ± 0.09
0.29AspTrp: 0.29 ± 0.024
2.263AspTyr: 2.263 ± 0.068
0.0AspXaa: 0.0 ± 0.0
Glu
4.433GluAla: 4.433 ± 0.117
0.842GluCys: 0.842 ± 0.046
2.388GluAsp: 2.388 ± 0.085
2.864GluGlu: 2.864 ± 0.097
4.655GluPhe: 4.655 ± 0.098
2.352GluGly: 2.352 ± 0.081
1.109GluHis: 1.109 ± 0.05
7.159GluIle: 7.159 ± 0.139
3.946GluLys: 3.946 ± 0.108
7.891GluLeu: 7.891 ± 0.135
1.471GluMet: 1.471 ± 0.058
4.013GluAsn: 4.013 ± 0.109
1.823GluPro: 1.823 ± 0.064
2.034GluGln: 2.034 ± 0.064
2.333GluArg: 2.333 ± 0.077
3.66GluSer: 3.66 ± 0.086
1.812GluThr: 1.812 ± 0.065
3.262GluVal: 3.262 ± 0.079
0.495GluTrp: 0.495 ± 0.031
2.69GluTyr: 2.69 ± 0.076
0.0GluXaa: 0.0 ± 0.0
Phe
3.453PheAla: 3.453 ± 0.087
0.718PheCys: 0.718 ± 0.044
3.876PheAsp: 3.876 ± 0.103
3.279PheGlu: 3.279 ± 0.084
2.14PhePhe: 2.14 ± 0.078
4.022PheGly: 4.022 ± 0.095
0.61PheHis: 0.61 ± 0.037
4.913PheIle: 4.913 ± 0.139
3.948PheLys: 3.948 ± 0.098
4.204PheLeu: 4.204 ± 0.103
1.295PheMet: 1.295 ± 0.059
2.892PheAsn: 2.892 ± 0.084
0.929PhePro: 0.929 ± 0.053
0.872PheGln: 0.872 ± 0.045
1.452PheArg: 1.452 ± 0.054
4.026PheSer: 4.026 ± 0.109
2.153PheThr: 2.153 ± 0.065
2.841PheVal: 2.841 ± 0.096
0.493PheTrp: 0.493 ± 0.038
2.019PheTyr: 2.019 ± 0.075
0.0PheXaa: 0.0 ± 0.0
Gly
4.979GlyAla: 4.979 ± 0.111
0.853GlyCys: 0.853 ± 0.045
3.592GlyAsp: 3.592 ± 0.086
3.675GlyGlu: 3.675 ± 0.106
3.876GlyPhe: 3.876 ± 0.103
4.435GlyGly: 4.435 ± 0.117
0.963GlyHis: 0.963 ± 0.046
5.593GlyIle: 5.593 ± 0.119
4.659GlyLys: 4.659 ± 0.11
5.857GlyLeu: 5.857 ± 0.126
1.56GlyMet: 1.56 ± 0.06
2.661GlyAsn: 2.661 ± 0.115
0.866GlyPro: 0.866 ± 0.05
1.689GlyGln: 1.689 ± 0.066
2.045GlyArg: 2.045 ± 0.066
4.092GlySer: 4.092 ± 0.104
2.443GlyThr: 2.443 ± 0.089
5.199GlyVal: 5.199 ± 0.133
0.449GlyTrp: 0.449 ± 0.029
2.722GlyTyr: 2.722 ± 0.075
0.0GlyXaa: 0.0 ± 0.0
His
1.054HisAla: 1.054 ± 0.047
0.203HisCys: 0.203 ± 0.02
0.665HisAsp: 0.665 ± 0.041
0.72HisGlu: 0.72 ± 0.041
0.857HisPhe: 0.857 ± 0.042
1.018HisGly: 1.018 ± 0.048
0.347HisHis: 0.347 ± 0.037
1.588HisIle: 1.588 ± 0.06
1.128HisLys: 1.128 ± 0.058
1.42HisLeu: 1.42 ± 0.054
0.354HisMet: 0.354 ± 0.026
0.809HisAsn: 0.809 ± 0.042
0.741HisPro: 0.741 ± 0.04
0.506HisGln: 0.506 ± 0.035
0.563HisArg: 0.563 ± 0.036
1.086HisSer: 1.086 ± 0.051
0.887HisThr: 0.887 ± 0.047
0.557HisVal: 0.557 ± 0.034
0.119HisTrp: 0.119 ± 0.019
0.658HisTyr: 0.658 ± 0.037
0.0HisXaa: 0.0 ± 0.0
Ile
7.601IleAla: 7.601 ± 0.154
1.344IleCys: 1.344 ± 0.061
6.24IleAsp: 6.24 ± 0.125
5.914IleGlu: 5.914 ± 0.124
4.771IlePhe: 4.771 ± 0.128
5.87IleGly: 5.87 ± 0.127
1.194IleHis: 1.194 ± 0.051
8.222IleIle: 8.222 ± 0.167
8.45IleLys: 8.45 ± 0.163
8.747IleLeu: 8.747 ± 0.155
1.973IleMet: 1.973 ± 0.066
5.933IleAsn: 5.933 ± 0.14
2.547IlePro: 2.547 ± 0.077
2.263IleGln: 2.263 ± 0.078
2.798IleArg: 2.798 ± 0.089
7.239IleSer: 7.239 ± 0.137
4.676IleThr: 4.676 ± 0.101
4.924IleVal: 4.924 ± 0.116
0.658IleTrp: 0.658 ± 0.038
3.768IleTyr: 3.768 ± 0.102
0.0IleXaa: 0.0 ± 0.0
Lys
5.874LysAla: 5.874 ± 0.125
0.705LysCys: 0.705 ± 0.045
5.734LysAsp: 5.734 ± 0.113
6.41LysGlu: 6.41 ± 0.141
5.167LysPhe: 5.167 ± 0.118
3.899LysGly: 3.899 ± 0.105
1.035LysHis: 1.035 ± 0.046
8.207LysIle: 8.207 ± 0.14
5.978LysLys: 5.978 ± 0.121
6.702LysLeu: 6.702 ± 0.112
2.11LysMet: 2.11 ± 0.068
5.957LysAsn: 5.957 ± 0.161
2.364LysPro: 2.364 ± 0.081
2.072LysGln: 2.072 ± 0.069
3.01LysArg: 3.01 ± 0.085
6.185LysSer: 6.185 ± 0.134
3.4LysThr: 3.4 ± 0.084
3.853LysVal: 3.853 ± 0.089
0.489LysTrp: 0.489 ± 0.033
2.856LysTyr: 2.856 ± 0.084
0.0LysXaa: 0.0 ± 0.0
Leu
7.866LeuAla: 7.866 ± 0.135
1.145LeuCys: 1.145 ± 0.052
5.741LeuAsp: 5.741 ± 0.134
6.348LeuGlu: 6.348 ± 0.116
4.291LeuPhe: 4.291 ± 0.116
6.403LeuGly: 6.403 ± 0.129
1.439LeuHis: 1.439 ± 0.062
8.014LeuIle: 8.014 ± 0.157
9.015LeuLys: 9.015 ± 0.148
7.921LeuLeu: 7.921 ± 0.154
2.053LeuMet: 2.053 ± 0.067
7.21LeuAsn: 7.21 ± 0.165
3.224LeuPro: 3.224 ± 0.091
2.491LeuGln: 2.491 ± 0.075
3.556LeuArg: 3.556 ± 0.096
7.75LeuSer: 7.75 ± 0.147
3.891LeuThr: 3.891 ± 0.089
4.845LeuVal: 4.845 ± 0.111
0.624LeuTrp: 0.624 ± 0.042
3.23LeuTyr: 3.23 ± 0.092
0.0LeuXaa: 0.0 ± 0.0
Met
2.03MetAla: 2.03 ± 0.077
0.201MetCys: 0.201 ± 0.024
1.338MetAsp: 1.338 ± 0.056
1.259MetGlu: 1.259 ± 0.048
0.851MetPhe: 0.851 ± 0.05
1.577MetGly: 1.577 ± 0.068
0.396MetHis: 0.396 ± 0.027
2.293MetIle: 2.293 ± 0.075
1.734MetLys: 1.734 ± 0.056
2.549MetLeu: 2.549 ± 0.072
0.586MetMet: 0.586 ± 0.038
1.259MetAsn: 1.259 ± 0.055
0.991MetPro: 0.991 ± 0.046
1.02MetGln: 1.02 ± 0.049
1.12MetArg: 1.12 ± 0.049
1.85MetSer: 1.85 ± 0.064
0.739MetThr: 0.739 ± 0.045
1.467MetVal: 1.467 ± 0.064
0.138MetTrp: 0.138 ± 0.016
0.481MetTyr: 0.481 ± 0.035
0.0MetXaa: 0.0 ± 0.0
Asn
4.346AsnAla: 4.346 ± 0.087
0.521AsnCys: 0.521 ± 0.031
3.279AsnAsp: 3.279 ± 0.086
4.229AsnGlu: 4.229 ± 0.091
2.777AsnPhe: 2.777 ± 0.071
3.927AsnGly: 3.927 ± 0.114
0.923AsnHis: 0.923 ± 0.046
6.043AsnIle: 6.043 ± 0.147
4.196AsnLys: 4.196 ± 0.122
7.682AsnLeu: 7.682 ± 0.165
1.181AsnMet: 1.181 ± 0.044
2.993AsnAsn: 2.993 ± 0.136
2.43AsnPro: 2.43 ± 0.069
2.223AsnGln: 2.223 ± 0.1
2.165AsnArg: 2.165 ± 0.07
5.279AsnSer: 5.279 ± 0.145
2.413AsnThr: 2.413 ± 0.08
2.475AsnVal: 2.475 ± 0.077
0.324AsnTrp: 0.324 ± 0.029
2.288AsnTyr: 2.288 ± 0.082
0.0AsnXaa: 0.0 ± 0.0
Pro
1.729ProAla: 1.729 ± 0.064
0.339ProCys: 0.339 ± 0.028
1.467ProAsp: 1.467 ± 0.057
1.414ProGlu: 1.414 ± 0.065
1.524ProPhe: 1.524 ± 0.053
1.363ProGly: 1.363 ± 0.047
0.58ProHis: 0.58 ± 0.038
2.447ProIle: 2.447 ± 0.075
2.777ProLys: 2.777 ± 0.084
2.942ProLeu: 2.942 ± 0.084
0.69ProMet: 0.69 ± 0.033
2.468ProAsn: 2.468 ± 0.082
0.807ProPro: 0.807 ± 0.048
0.959ProGln: 0.959 ± 0.049
0.94ProArg: 0.94 ± 0.047
2.153ProSer: 2.153 ± 0.085
1.609ProThr: 1.609 ± 0.059
1.878ProVal: 1.878 ± 0.069
0.21ProTrp: 0.21 ± 0.022
1.202ProTyr: 1.202 ± 0.05
0.0ProXaa: 0.0 ± 0.0
Gln
1.992GlnAla: 1.992 ± 0.076
0.229GlnCys: 0.229 ± 0.025
1.382GlnAsp: 1.382 ± 0.058
1.562GlnGlu: 1.562 ± 0.058
0.969GlnPhe: 0.969 ± 0.045
1.401GlnGly: 1.401 ± 0.055
0.326GlnHis: 0.326 ± 0.026
3.863GlnIle: 3.863 ± 0.099
3.067GlnLys: 3.067 ± 0.093
1.975GlnLeu: 1.975 ± 0.063
0.758GlnMet: 0.758 ± 0.039
3.275GlnAsn: 3.275 ± 0.099
0.688GlnPro: 0.688 ± 0.043
0.665GlnGln: 0.665 ± 0.043
1.082GlnArg: 1.082 ± 0.049
2.085GlnSer: 2.085 ± 0.08
1.74GlnThr: 1.74 ± 0.068
1.257GlnVal: 1.257 ± 0.057
0.212GlnTrp: 0.212 ± 0.02
0.696GlnTyr: 0.696 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.925ArgAla: 2.925 ± 0.087
0.324ArgCys: 0.324 ± 0.027
2.307ArgAsp: 2.307 ± 0.068
2.127ArgGlu: 2.127 ± 0.079
1.884ArgPhe: 1.884 ± 0.06
1.947ArgGly: 1.947 ± 0.071
0.546ArgHis: 0.546 ± 0.035
2.868ArgIle: 2.868 ± 0.08
2.1ArgLys: 2.1 ± 0.069
3.874ArgLeu: 3.874 ± 0.099
0.771ArgMet: 0.771 ± 0.041
1.617ArgAsn: 1.617 ± 0.057
1.063ArgPro: 1.063 ± 0.052
1.173ArgGln: 1.173 ± 0.055
1.3ArgArg: 1.3 ± 0.063
2.159ArgSer: 2.159 ± 0.073
1.281ArgThr: 1.281 ± 0.058
2.572ArgVal: 2.572 ± 0.076
0.26ArgTrp: 0.26 ± 0.023
1.617ArgTyr: 1.617 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
5.015SerAla: 5.015 ± 0.122
0.711SerCys: 0.711 ± 0.046
4.574SerAsp: 4.574 ± 0.107
3.952SerGlu: 3.952 ± 0.093
3.531SerPhe: 3.531 ± 0.1
5.184SerGly: 5.184 ± 0.126
1.236SerHis: 1.236 ± 0.052
5.916SerIle: 5.916 ± 0.122
6.132SerLys: 6.132 ± 0.122
6.892SerLeu: 6.892 ± 0.141
1.511SerMet: 1.511 ± 0.053
4.219SerAsn: 4.219 ± 0.11
1.914SerPro: 1.914 ± 0.071
2.68SerGln: 2.68 ± 0.078
2.489SerArg: 2.489 ± 0.074
5.624SerSer: 5.624 ± 0.113
2.936SerThr: 2.936 ± 0.096
4.401SerVal: 4.401 ± 0.101
0.542SerTrp: 0.542 ± 0.035
2.809SerTyr: 2.809 ± 0.084
0.0SerXaa: 0.0 ± 0.0
Thr
3.105ThrAla: 3.105 ± 0.105
0.318ThrCys: 0.318 ± 0.026
1.994ThrAsp: 1.994 ± 0.07
1.564ThrGlu: 1.564 ± 0.066
1.617ThrPhe: 1.617 ± 0.067
2.659ThrGly: 2.659 ± 0.087
0.98ThrHis: 0.98 ± 0.052
4.38ThrIle: 4.38 ± 0.097
3.842ThrLys: 3.842 ± 0.095
4.723ThrLeu: 4.723 ± 0.105
0.986ThrMet: 0.986 ± 0.048
2.676ThrAsn: 2.676 ± 0.084
2.318ThrPro: 2.318 ± 0.069
2.009ThrGln: 2.009 ± 0.076
1.321ThrArg: 1.321 ± 0.057
2.735ThrSer: 2.735 ± 0.079
2.638ThrThr: 2.638 ± 0.084
1.736ThrVal: 1.736 ± 0.076
0.22ThrTrp: 0.22 ± 0.021
1.342ThrTyr: 1.342 ± 0.052
0.0ThrXaa: 0.0 ± 0.0
Val
5.0ValAla: 5.0 ± 0.105
0.775ValCys: 0.775 ± 0.043
3.26ValAsp: 3.26 ± 0.088
3.408ValGlu: 3.408 ± 0.082
2.398ValPhe: 2.398 ± 0.085
3.772ValGly: 3.772 ± 0.104
0.66ValHis: 0.66 ± 0.037
4.989ValIle: 4.989 ± 0.104
3.963ValLys: 3.963 ± 0.093
5.392ValLeu: 5.392 ± 0.124
1.403ValMet: 1.403 ± 0.057
2.845ValAsn: 2.845 ± 0.09
1.579ValPro: 1.579 ± 0.054
1.179ValGln: 1.179 ± 0.052
1.808ValArg: 1.808 ± 0.065
3.971ValSer: 3.971 ± 0.101
2.104ValThr: 2.104 ± 0.072
4.348ValVal: 4.348 ± 0.119
0.394ValTrp: 0.394 ± 0.029
1.753ValTyr: 1.753 ± 0.068
0.0ValXaa: 0.0 ± 0.0
Trp
0.588TrpAla: 0.588 ± 0.035
0.121TrpCys: 0.121 ± 0.018
0.421TrpAsp: 0.421 ± 0.034
0.311TrpGlu: 0.311 ± 0.026
0.305TrpPhe: 0.305 ± 0.024
0.508TrpGly: 0.508 ± 0.044
0.163TrpHis: 0.163 ± 0.022
0.637TrpIle: 0.637 ± 0.04
0.326TrpLys: 0.326 ± 0.032
0.809TrpLeu: 0.809 ± 0.046
0.205TrpMet: 0.205 ± 0.022
0.324TrpAsn: 0.324 ± 0.027
0.11TrpPro: 0.11 ± 0.014
0.322TrpGln: 0.322 ± 0.033
0.269TrpArg: 0.269 ± 0.026
0.349TrpSer: 0.349 ± 0.03
0.197TrpThr: 0.197 ± 0.024
0.4TrpVal: 0.4 ± 0.033
0.104TrpTrp: 0.104 ± 0.016
0.282TrpTyr: 0.282 ± 0.026
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.602TyrAla: 2.602 ± 0.069
0.409TyrCys: 0.409 ± 0.033
2.375TyrAsp: 2.375 ± 0.071
2.743TyrGlu: 2.743 ± 0.084
2.022TyrPhe: 2.022 ± 0.06
2.248TyrGly: 2.248 ± 0.067
0.658TyrHis: 0.658 ± 0.034
3.122TyrIle: 3.122 ± 0.08
3.311TyrLys: 3.311 ± 0.089
3.588TyrLeu: 3.588 ± 0.109
0.819TyrMet: 0.819 ± 0.046
2.155TyrAsn: 2.155 ± 0.072
1.251TyrPro: 1.251 ± 0.048
1.221TyrGln: 1.221 ± 0.056
1.245TyrArg: 1.245 ± 0.053
2.538TyrSer: 2.538 ± 0.071
1.672TyrThr: 1.672 ± 0.068
1.378TyrVal: 1.378 ± 0.053
0.188TyrTrp: 0.188 ± 0.021
1.547TyrTyr: 1.547 ± 0.066
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1504 proteins (472411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski