Amino acid dipepetide frequency for Ulvibacter litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.685AlaAla: 4.685 ± 0.089	0.563AlaCys: 0.563 ± 0.023	3.189AlaAsp: 3.189 ± 0.057	4.031AlaGlu: 4.031 ± 0.071	3.38AlaPhe: 3.38 ± 0.055	4.294AlaGly: 4.294 ± 0.084	1.141AlaHis: 1.141 ± 0.034	5.619AlaIle: 5.619 ± 0.075	4.489AlaLys: 4.489 ± 0.073	6.419AlaLeu: 6.419 ± 0.092	1.578AlaMet: 1.578 ± 0.04	3.653AlaAsn: 3.653 ± 0.068	2.132AlaPro: 2.132 ± 0.049	2.462AlaGln: 2.462 ± 0.051	1.945AlaArg: 1.945 ± 0.051	5.188AlaSer: 5.188 ± 0.087	4.617AlaThr: 4.617 ± 0.084	4.327AlaVal: 4.327 ± 0.069	0.576AlaTrp: 0.576 ± 0.021	2.545AlaTyr: 2.545 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.478CysAla: 0.478 ± 0.022	0.084CysCys: 0.084 ± 0.008	0.506CysAsp: 0.506 ± 0.033	0.503CysGlu: 0.503 ± 0.026	0.419CysPhe: 0.419 ± 0.019	0.64CysGly: 0.64 ± 0.027	0.158CysHis: 0.158 ± 0.012	0.592CysIle: 0.592 ± 0.025	0.44CysLys: 0.44 ± 0.022	0.62CysLeu: 0.62 ± 0.025	0.136CysMet: 0.136 ± 0.011	0.421CysAsn: 0.421 ± 0.02	0.328CysPro: 0.328 ± 0.025	0.192CysGln: 0.192 ± 0.015	0.184CysArg: 0.184 ± 0.013	0.564CysSer: 0.564 ± 0.025	0.508CysThr: 0.508 ± 0.028	0.481CysVal: 0.481 ± 0.029	0.068CysTrp: 0.068 ± 0.009	0.291CysTyr: 0.291 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.229AspAla: 4.229 ± 0.088	0.464AspCys: 0.464 ± 0.026	3.056AspAsp: 3.056 ± 0.084	3.478AspGlu: 3.478 ± 0.074	3.57AspPhe: 3.57 ± 0.07	3.941AspGly: 3.941 ± 0.081	0.822AspHis: 0.822 ± 0.031	4.417AspIle: 4.417 ± 0.063	3.383AspLys: 3.383 ± 0.059	5.043AspLeu: 5.043 ± 0.077	0.998AspMet: 0.998 ± 0.03	2.845AspAsn: 2.845 ± 0.059	1.953AspPro: 1.953 ± 0.059	1.374AspGln: 1.374 ± 0.035	1.766AspArg: 1.766 ± 0.041	3.271AspSer: 3.271 ± 0.059	3.336AspThr: 3.336 ± 0.061	3.792AspVal: 3.792 ± 0.061	0.713AspTrp: 0.713 ± 0.026	2.641AspTyr: 2.641 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	5.29GluAla: 5.29 ± 0.074	0.344GluCys: 0.344 ± 0.016	3.656GluAsp: 3.656 ± 0.065	4.96GluGlu: 4.96 ± 0.08	2.894GluPhe: 2.894 ± 0.052	4.246GluGly: 4.246 ± 0.067	1.141GluHis: 1.141 ± 0.03	5.476GluIle: 5.476 ± 0.084	5.815GluLys: 5.815 ± 0.092	6.053GluLeu: 6.053 ± 0.084	1.588GluMet: 1.588 ± 0.039	4.708GluAsn: 4.708 ± 0.071	1.483GluPro: 1.483 ± 0.037	2.097GluGln: 2.097 ± 0.047	2.511GluArg: 2.511 ± 0.052	3.454GluSer: 3.454 ± 0.052	4.502GluThr: 4.502 ± 0.067	4.547GluVal: 4.547 ± 0.066	0.583GluTrp: 0.583 ± 0.028	2.491GluTyr: 2.491 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	2.909PheAla: 2.909 ± 0.047	0.414PheCys: 0.414 ± 0.019	3.15PheAsp: 3.15 ± 0.063	3.581PheGlu: 3.581 ± 0.066	2.777PhePhe: 2.777 ± 0.058	3.644PheGly: 3.644 ± 0.067	0.8PheHis: 0.8 ± 0.028	3.67PheIle: 3.67 ± 0.069	3.481PheLys: 3.481 ± 0.07	4.801PheLeu: 4.801 ± 0.084	1.081PheMet: 1.081 ± 0.035	3.058PheAsn: 3.058 ± 0.059	1.785PhePro: 1.785 ± 0.039	1.624PheGln: 1.624 ± 0.037	1.522PheArg: 1.522 ± 0.04	4.354PheSer: 4.354 ± 0.072	3.341PheThr: 3.341 ± 0.065	3.091PheVal: 3.091 ± 0.052	0.556PheTrp: 0.556 ± 0.025	2.181PheTyr: 2.181 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.491GlyAla: 4.491 ± 0.086	0.571GlyCys: 0.571 ± 0.027	3.634GlyAsp: 3.634 ± 0.086	3.584GlyGlu: 3.584 ± 0.057	3.617GlyPhe: 3.617 ± 0.062	4.814GlyGly: 4.814 ± 0.119	1.097GlyHis: 1.097 ± 0.031	5.527GlyIle: 5.527 ± 0.081	4.404GlyLys: 4.404 ± 0.078	5.558GlyLeu: 5.558 ± 0.086	1.635GlyMet: 1.635 ± 0.038	3.832GlyAsn: 3.832 ± 0.07	1.4GlyPro: 1.4 ± 0.036	1.763GlyGln: 1.763 ± 0.041	1.977GlyArg: 1.977 ± 0.045	4.206GlySer: 4.206 ± 0.08	4.785GlyThr: 4.785 ± 0.109	4.667GlyVal: 4.667 ± 0.071	0.691GlyTrp: 0.691 ± 0.023	2.766GlyTyr: 2.766 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	0.912HisAla: 0.912 ± 0.032	0.186HisCys: 0.186 ± 0.014	0.777HisAsp: 0.777 ± 0.026	0.915HisGlu: 0.915 ± 0.028	1.151HisPhe: 1.151 ± 0.036	0.959HisGly: 0.959 ± 0.033	0.463HisHis: 0.463 ± 0.023	1.402HisIle: 1.402 ± 0.034	1.215HisLys: 1.215 ± 0.035	1.74HisLeu: 1.74 ± 0.044	0.291HisMet: 0.291 ± 0.015	0.925HisAsn: 0.925 ± 0.024	0.915HisPro: 0.915 ± 0.032	0.632HisGln: 0.632 ± 0.022	0.625HisArg: 0.625 ± 0.025	1.085HisSer: 1.085 ± 0.031	1.031HisThr: 1.031 ± 0.028	0.888HisVal: 0.888 ± 0.032	0.21HisTrp: 0.21 ± 0.011	0.8HisTyr: 0.8 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.875IleAla: 5.875 ± 0.096	0.602IleCys: 0.602 ± 0.023	4.902IleAsp: 4.902 ± 0.072	5.698IleGlu: 5.698 ± 0.074	3.376IlePhe: 3.376 ± 0.064	5.017IleGly: 5.017 ± 0.082	1.294IleHis: 1.294 ± 0.037	5.543IleIle: 5.543 ± 0.097	5.051IleLys: 5.051 ± 0.076	6.814IleLeu: 6.814 ± 0.085	1.213IleMet: 1.213 ± 0.033	4.339IleAsn: 4.339 ± 0.082	3.205IlePro: 3.205 ± 0.058	2.636IleGln: 2.636 ± 0.051	2.356IleArg: 2.356 ± 0.045	5.776IleSer: 5.776 ± 0.08	5.37IleThr: 5.37 ± 0.086	4.9IleVal: 4.9 ± 0.069	0.609IleTrp: 0.609 ± 0.021	2.571IleTyr: 2.571 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.747LysAla: 4.747 ± 0.086	0.327LysCys: 0.327 ± 0.017	4.122LysAsp: 4.122 ± 0.066	6.177LysGlu: 6.177 ± 0.085	2.622LysPhe: 2.622 ± 0.054	4.298LysGly: 4.298 ± 0.072	1.329LysHis: 1.329 ± 0.033	5.543LysIle: 5.543 ± 0.085	6.786LysLys: 6.786 ± 0.091	6.228LysLeu: 6.228 ± 0.096	1.935LysMet: 1.935 ± 0.043	4.879LysAsn: 4.879 ± 0.07	2.18LysPro: 2.18 ± 0.05	2.603LysGln: 2.603 ± 0.043	2.796LysArg: 2.796 ± 0.055	4.091LysSer: 4.091 ± 0.07	4.65LysThr: 4.65 ± 0.067	4.419LysVal: 4.419 ± 0.071	0.669LysTrp: 0.669 ± 0.027	2.677LysTyr: 2.677 ± 0.063	0.0LysXaa: 0.0 ± 0.0
Leu	5.878LeuAla: 5.878 ± 0.086	0.691LeuCys: 0.691 ± 0.027	5.012LeuAsp: 5.012 ± 0.079	6.089LeuGlu: 6.089 ± 0.094	5.11LeuPhe: 5.11 ± 0.08	5.764LeuGly: 5.764 ± 0.074	1.667LeuHis: 1.667 ± 0.043	6.53LeuIle: 6.53 ± 0.091	7.305LeuLys: 7.305 ± 0.093	9.349LeuLeu: 9.349 ± 0.144	1.86LeuMet: 1.86 ± 0.044	5.209LeuAsn: 5.209 ± 0.076	3.401LeuPro: 3.401 ± 0.061	3.64LeuGln: 3.64 ± 0.057	3.054LeuArg: 3.054 ± 0.052	6.762LeuSer: 6.762 ± 0.084	5.413LeuThr: 5.413 ± 0.069	5.672LeuVal: 5.672 ± 0.072	0.782LeuTrp: 0.782 ± 0.03	3.237LeuTyr: 3.237 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	1.501MetAla: 1.501 ± 0.038	0.14MetCys: 0.14 ± 0.011	1.06MetAsp: 1.06 ± 0.034	1.402MetGlu: 1.402 ± 0.04	0.783MetPhe: 0.783 ± 0.032	1.419MetGly: 1.419 ± 0.036	0.356MetHis: 0.356 ± 0.017	1.423MetIle: 1.423 ± 0.041	2.178MetLys: 2.178 ± 0.04	1.876MetLeu: 1.876 ± 0.043	0.533MetMet: 0.533 ± 0.022	1.224MetAsn: 1.224 ± 0.029	0.803MetPro: 0.803 ± 0.026	0.733MetGln: 0.733 ± 0.028	0.831MetArg: 0.831 ± 0.025	1.33MetSer: 1.33 ± 0.038	1.121MetThr: 1.121 ± 0.031	1.345MetVal: 1.345 ± 0.032	0.144MetTrp: 0.144 ± 0.011	0.736MetTyr: 0.736 ± 0.03	0.0MetXaa: 0.0 ± 0.0
Asn	3.97AsnAla: 3.97 ± 0.075	0.502AsnCys: 0.502 ± 0.028	3.311AsnAsp: 3.311 ± 0.066	3.756AsnGlu: 3.756 ± 0.063	2.964AsnPhe: 2.964 ± 0.054	4.234AsnGly: 4.234 ± 0.064	0.94AsnHis: 0.94 ± 0.03	4.429AsnIle: 4.429 ± 0.068	3.802AsnLys: 3.802 ± 0.068	5.212AsnLeu: 5.212 ± 0.073	1.164AsnMet: 1.164 ± 0.035	3.689AsnAsn: 3.689 ± 0.068	2.728AsnPro: 2.728 ± 0.051	2.012AsnGln: 2.012 ± 0.049	2.027AsnArg: 2.027 ± 0.044	3.771AsnSer: 3.771 ± 0.068	4.0AsnThr: 4.0 ± 0.08	3.625AsnVal: 3.625 ± 0.067	0.71AsnTrp: 0.71 ± 0.03	2.67AsnTyr: 2.67 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	1.963ProAla: 1.963 ± 0.051	0.227ProCys: 0.227 ± 0.015	1.939ProAsp: 1.939 ± 0.046	2.691ProGlu: 2.691 ± 0.05	1.976ProPhe: 1.976 ± 0.051	1.953ProGly: 1.953 ± 0.053	0.554ProHis: 0.554 ± 0.024	2.721ProIle: 2.721 ± 0.054	2.51ProLys: 2.51 ± 0.051	3.046ProLeu: 3.046 ± 0.058	0.693ProMet: 0.693 ± 0.025	2.323ProAsn: 2.323 ± 0.05	0.894ProPro: 0.894 ± 0.036	1.114ProGln: 1.114 ± 0.033	0.865ProArg: 0.865 ± 0.033	2.441ProSer: 2.441 ± 0.043	2.226ProThr: 2.226 ± 0.059	2.291ProVal: 2.291 ± 0.05	0.311ProTrp: 0.311 ± 0.018	1.321ProTyr: 1.321 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	1.963GlnAla: 1.963 ± 0.045	0.172GlnCys: 0.172 ± 0.01	1.662GlnAsp: 1.662 ± 0.041	2.278GlnGlu: 2.278 ± 0.05	1.674GlnPhe: 1.674 ± 0.037	1.801GlnGly: 1.801 ± 0.044	0.615GlnHis: 0.615 ± 0.024	2.465GlnIle: 2.465 ± 0.049	2.869GlnLys: 2.869 ± 0.054	3.599GlnLeu: 3.599 ± 0.065	0.77GlnMet: 0.77 ± 0.028	2.122GlnAsn: 2.122 ± 0.043	1.022GlnPro: 1.022 ± 0.03	1.446GlnGln: 1.446 ± 0.045	1.208GlnArg: 1.208 ± 0.034	1.864GlnSer: 1.864 ± 0.044	1.917GlnThr: 1.917 ± 0.041	1.934GlnVal: 1.934 ± 0.039	0.359GlnTrp: 0.359 ± 0.019	1.355GlnTyr: 1.355 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.004ArgAla: 2.004 ± 0.044	0.188ArgCys: 0.188 ± 0.013	1.792ArgAsp: 1.792 ± 0.045	2.072ArgGlu: 2.072 ± 0.044	1.845ArgPhe: 1.845 ± 0.043	1.846ArgGly: 1.846 ± 0.047	0.535ArgHis: 0.535 ± 0.018	2.701ArgIle: 2.701 ± 0.049	2.727ArgLys: 2.727 ± 0.048	3.034ArgLeu: 3.034 ± 0.063	0.808ArgMet: 0.808 ± 0.029	2.022ArgAsn: 2.022 ± 0.038	0.998ArgPro: 0.998 ± 0.031	0.992ArgGln: 0.992 ± 0.033	1.23ArgArg: 1.23 ± 0.034	1.871ArgSer: 1.871 ± 0.047	1.882ArgThr: 1.882 ± 0.041	2.082ArgVal: 2.082 ± 0.049	0.319ArgTrp: 0.319 ± 0.019	1.457ArgTyr: 1.457 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	3.801SerAla: 3.801 ± 0.06	0.705SerCys: 0.705 ± 0.029	3.52SerAsp: 3.52 ± 0.067	5.859SerGlu: 5.859 ± 0.084	3.962SerPhe: 3.962 ± 0.066	4.76SerGly: 4.76 ± 0.082	1.069SerHis: 1.069 ± 0.032	5.456SerIle: 5.456 ± 0.079	4.813SerLys: 4.813 ± 0.067	6.077SerLeu: 6.077 ± 0.087	1.245SerMet: 1.245 ± 0.031	3.852SerAsn: 3.852 ± 0.064	2.184SerPro: 2.184 ± 0.045	2.043SerGln: 2.043 ± 0.046	1.964SerArg: 1.964 ± 0.04	4.315SerSer: 4.315 ± 0.074	3.839SerThr: 3.839 ± 0.083	4.214SerVal: 4.214 ± 0.075	0.632SerTrp: 0.632 ± 0.026	2.752SerTyr: 2.752 ± 0.057	0.0SerXaa: 0.0 ± 0.0
Thr	4.451ThrAla: 4.451 ± 0.086	0.435ThrCys: 0.435 ± 0.035	3.423ThrAsp: 3.423 ± 0.081	4.019ThrGlu: 4.019 ± 0.068	3.341ThrPhe: 3.341 ± 0.06	4.282ThrGly: 4.282 ± 0.094	1.121ThrHis: 1.121 ± 0.031	5.442ThrIle: 5.442 ± 0.077	4.019ThrLys: 4.019 ± 0.071	6.074ThrLeu: 6.074 ± 0.072	1.119ThrMet: 1.119 ± 0.027	3.703ThrAsn: 3.703 ± 0.063	2.754ThrPro: 2.754 ± 0.063	2.111ThrGln: 2.111 ± 0.047	1.679ThrArg: 1.679 ± 0.038	4.407ThrSer: 4.407 ± 0.077	4.565ThrThr: 4.565 ± 0.088	4.622ThrVal: 4.622 ± 0.101	0.637ThrTrp: 0.637 ± 0.028	2.648ThrTyr: 2.648 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	4.655ValAla: 4.655 ± 0.071	0.553ValCys: 0.553 ± 0.023	3.453ValAsp: 3.453 ± 0.058	3.826ValGlu: 3.826 ± 0.066	3.463ValPhe: 3.463 ± 0.056	3.977ValGly: 3.977 ± 0.057	1.05ValHis: 1.05 ± 0.031	4.755ValIle: 4.755 ± 0.074	4.19ValLys: 4.19 ± 0.069	6.329ValLeu: 6.329 ± 0.074	1.289ValMet: 1.289 ± 0.04	3.444ValAsn: 3.444 ± 0.055	2.233ValPro: 2.233 ± 0.044	1.845ValGln: 1.845 ± 0.046	2.01ValArg: 2.01 ± 0.043	5.002ValSer: 5.002 ± 0.081	4.554ValThr: 4.554 ± 0.101	4.564ValVal: 4.564 ± 0.07	0.663ValTrp: 0.663 ± 0.025	2.522ValTyr: 2.522 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.588TrpAla: 0.588 ± 0.022	0.083TrpCys: 0.083 ± 0.007	0.588TrpAsp: 0.588 ± 0.027	0.685TrpGlu: 0.685 ± 0.029	0.528TrpPhe: 0.528 ± 0.027	0.59TrpGly: 0.59 ± 0.024	0.215TrpHis: 0.215 ± 0.013	0.719TrpIle: 0.719 ± 0.026	0.711TrpLys: 0.711 ± 0.026	0.905TrpLeu: 0.905 ± 0.033	0.306TrpMet: 0.306 ± 0.018	0.694TrpAsn: 0.694 ± 0.028	0.217TrpPro: 0.217 ± 0.014	0.328TrpGln: 0.328 ± 0.02	0.362TrpArg: 0.362 ± 0.018	0.568TrpSer: 0.568 ± 0.025	0.556TrpThr: 0.556 ± 0.026	0.647TrpVal: 0.647 ± 0.024	0.131TrpTrp: 0.131 ± 0.012	0.407TrpTyr: 0.407 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.441TyrAla: 2.441 ± 0.049	0.359TyrCys: 0.359 ± 0.024	2.34TyrAsp: 2.34 ± 0.053	2.234TyrGlu: 2.234 ± 0.046	2.368TyrPhe: 2.368 ± 0.048	2.54TyrGly: 2.54 ± 0.053	0.757TyrHis: 0.757 ± 0.027	2.719TyrIle: 2.719 ± 0.052	2.89TyrLys: 2.89 ± 0.064	3.648TyrLeu: 3.648 ± 0.062	0.695TyrMet: 0.695 ± 0.023	2.576TyrAsn: 2.576 ± 0.058	1.443TyrPro: 1.443 ± 0.039	1.451TyrGln: 1.451 ± 0.039	1.494TyrArg: 1.494 ± 0.04	2.74TyrSer: 2.74 ± 0.057	2.64TyrThr: 2.64 ± 0.056	2.266TyrVal: 2.266 ± 0.046	0.466TyrTrp: 0.466 ± 0.022	1.81TyrTyr: 1.81 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3476 proteins (1153833 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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