Amino acid dipepetide frequency for Sanguibacter keddieii (strain ATCC 51767 / DSM 10542 / NCFB 3025 / ST-74)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.391AlaAla: 20.391 ± 0.198	0.711AlaCys: 0.711 ± 0.029	8.467AlaAsp: 8.467 ± 0.084	7.912AlaGlu: 7.912 ± 0.099	3.361AlaPhe: 3.361 ± 0.059	12.639AlaGly: 12.639 ± 0.129	2.475AlaHis: 2.475 ± 0.052	3.863AlaIle: 3.863 ± 0.065	1.927AlaLys: 1.927 ± 0.046	14.289AlaLeu: 14.289 ± 0.151	2.316AlaMet: 2.316 ± 0.04	1.734AlaAsn: 1.734 ± 0.04	7.78AlaPro: 7.78 ± 0.125	4.214AlaGln: 4.214 ± 0.072	9.625AlaArg: 9.625 ± 0.122	7.53AlaSer: 7.53 ± 0.074	8.474AlaThr: 8.474 ± 0.108	13.009AlaVal: 13.009 ± 0.124	1.927AlaTrp: 1.927 ± 0.041	2.201AlaTyr: 2.201 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.68CysAla: 0.68 ± 0.027	0.051CysCys: 0.051 ± 0.007	0.313CysAsp: 0.313 ± 0.018	0.263CysGlu: 0.263 ± 0.014	0.161CysPhe: 0.161 ± 0.011	0.573CysGly: 0.573 ± 0.021	0.099CysHis: 0.099 ± 0.008	0.133CysIle: 0.133 ± 0.009	0.053CysLys: 0.053 ± 0.007	0.489CysLeu: 0.489 ± 0.021	0.076CysMet: 0.076 ± 0.009	0.078CysAsn: 0.078 ± 0.008	0.313CysPro: 0.313 ± 0.016	0.128CysGln: 0.128 ± 0.009	0.334CysArg: 0.334 ± 0.017	0.402CysSer: 0.402 ± 0.019	0.365CysThr: 0.365 ± 0.016	0.482CysVal: 0.482 ± 0.02	0.06CysTrp: 0.06 ± 0.008	0.111CysTyr: 0.111 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.808AspAla: 8.808 ± 0.102	0.253AspCys: 0.253 ± 0.016	5.0AspAsp: 5.0 ± 0.076	4.48AspGlu: 4.48 ± 0.067	1.391AspPhe: 1.391 ± 0.038	7.223AspGly: 7.223 ± 0.114	1.463AspHis: 1.463 ± 0.043	1.79AspIle: 1.79 ± 0.042	0.808AspLys: 0.808 ± 0.027	7.313AspLeu: 7.313 ± 0.089	0.805AspMet: 0.805 ± 0.025	0.757AspAsn: 0.757 ± 0.026	4.408AspPro: 4.408 ± 0.069	1.835AspGln: 1.835 ± 0.045	4.453AspArg: 4.453 ± 0.075	2.777AspSer: 2.777 ± 0.053	3.025AspThr: 3.025 ± 0.042	6.629AspVal: 6.629 ± 0.084	0.83AspTrp: 0.83 ± 0.024	1.134AspTyr: 1.134 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	7.19GluAla: 7.19 ± 0.099	0.235GluCys: 0.235 ± 0.015	2.982GluAsp: 2.982 ± 0.057	2.798GluGlu: 2.798 ± 0.053	1.114GluPhe: 1.114 ± 0.03	4.18GluGly: 4.18 ± 0.061	1.819GluHis: 1.819 ± 0.045	2.507GluIle: 2.507 ± 0.045	1.105GluLys: 1.105 ± 0.034	5.894GluLeu: 5.894 ± 0.073	0.892GluMet: 0.892 ± 0.029	0.972GluAsn: 0.972 ± 0.031	3.47GluPro: 3.47 ± 0.067	2.294GluGln: 2.294 ± 0.047	4.67GluArg: 4.67 ± 0.073	2.794GluSer: 2.794 ± 0.059	3.461GluThr: 3.461 ± 0.06	5.521GluVal: 5.521 ± 0.076	0.661GluTrp: 0.661 ± 0.023	0.951GluTyr: 0.951 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.39PheAla: 3.39 ± 0.052	0.17PheCys: 0.17 ± 0.012	1.898PheAsp: 1.898 ± 0.04	1.469PheGlu: 1.469 ± 0.038	0.899PhePhe: 0.899 ± 0.031	2.693PheGly: 2.693 ± 0.056	0.487PheHis: 0.487 ± 0.017	0.72PheIle: 0.72 ± 0.026	0.354PheLys: 0.354 ± 0.02	2.431PheLeu: 2.431 ± 0.051	0.39PheMet: 0.39 ± 0.016	0.481PheAsn: 0.481 ± 0.02	1.23PhePro: 1.23 ± 0.037	0.677PheGln: 0.677 ± 0.023	1.485PheArg: 1.485 ± 0.033	1.723PheSer: 1.723 ± 0.04	1.886PheThr: 1.886 ± 0.041	2.726PheVal: 2.726 ± 0.05	0.446PheTrp: 0.446 ± 0.021	0.573PheTyr: 0.573 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	11.612GlyAla: 11.612 ± 0.112	0.545GlyCys: 0.545 ± 0.022	5.391GlyAsp: 5.391 ± 0.077	4.826GlyGlu: 4.826 ± 0.067	2.77GlyPhe: 2.77 ± 0.044	7.508GlyGly: 7.508 ± 0.101	1.839GlyHis: 1.839 ± 0.045	3.562GlyIle: 3.562 ± 0.061	1.723GlyLys: 1.723 ± 0.042	9.375GlyLeu: 9.375 ± 0.099	1.892GlyMet: 1.892 ± 0.04	1.344GlyAsn: 1.344 ± 0.038	4.515GlyPro: 4.515 ± 0.068	2.722GlyGln: 2.722 ± 0.05	6.514GlyArg: 6.514 ± 0.076	6.14GlySer: 6.14 ± 0.082	7.045GlyThr: 7.045 ± 0.114	8.149GlyVal: 8.149 ± 0.088	1.676GlyTrp: 1.676 ± 0.041	2.156GlyTyr: 2.156 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.358HisAla: 2.358 ± 0.05	0.108HisCys: 0.108 ± 0.01	1.526HisAsp: 1.526 ± 0.042	1.238HisGlu: 1.238 ± 0.037	0.44HisPhe: 0.44 ± 0.019	2.124HisGly: 2.124 ± 0.042	0.581HisHis: 0.581 ± 0.025	0.442HisIle: 0.442 ± 0.021	0.216HisLys: 0.216 ± 0.013	2.262HisLeu: 2.262 ± 0.049	0.272HisMet: 0.272 ± 0.013	0.297HisAsn: 0.297 ± 0.017	1.49HisPro: 1.49 ± 0.036	0.56HisGln: 0.56 ± 0.02	1.648HisArg: 1.648 ± 0.04	0.957HisSer: 0.957 ± 0.03	1.047HisThr: 1.047 ± 0.031	1.997HisVal: 1.997 ± 0.044	0.253HisTrp: 0.253 ± 0.014	0.37HisTyr: 0.37 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	4.512IleAla: 4.512 ± 0.072	0.191IleCys: 0.191 ± 0.011	2.327IleAsp: 2.327 ± 0.051	1.902IleGlu: 1.902 ± 0.044	0.898IlePhe: 0.898 ± 0.03	3.203IleGly: 3.203 ± 0.062	0.518IleHis: 0.518 ± 0.021	1.118IleIle: 1.118 ± 0.035	0.585IleLys: 0.585 ± 0.025	2.679IleLeu: 2.679 ± 0.049	0.494IleMet: 0.494 ± 0.019	0.652IleAsn: 0.652 ± 0.024	1.612IlePro: 1.612 ± 0.037	0.702IleGln: 0.702 ± 0.024	1.822IleArg: 1.822 ± 0.039	1.875IleSer: 1.875 ± 0.042	2.391IleThr: 2.391 ± 0.057	3.167IleVal: 3.167 ± 0.067	0.323IleTrp: 0.323 ± 0.015	0.509IleTyr: 0.509 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	1.953LysAla: 1.953 ± 0.051	0.058LysCys: 0.058 ± 0.006	0.972LysAsp: 0.972 ± 0.033	0.726LysGlu: 0.726 ± 0.031	0.352LysPhe: 0.352 ± 0.017	1.231LysGly: 1.231 ± 0.038	0.374LysHis: 0.374 ± 0.018	0.811LysIle: 0.811 ± 0.033	0.58LysLys: 0.58 ± 0.029	1.187LysLeu: 1.187 ± 0.035	0.287LysMet: 0.287 ± 0.017	0.418LysAsn: 0.418 ± 0.017	0.874LysPro: 0.874 ± 0.031	0.461LysGln: 0.461 ± 0.019	0.99LysArg: 0.99 ± 0.035	0.914LysSer: 0.914 ± 0.028	1.16LysThr: 1.16 ± 0.036	1.513LysVal: 1.513 ± 0.043	0.122LysTrp: 0.122 ± 0.009	0.325LysTyr: 0.325 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	14.871LeuAla: 14.871 ± 0.139	0.55LeuCys: 0.55 ± 0.02	7.536LeuAsp: 7.536 ± 0.091	5.21LeuGlu: 5.21 ± 0.066	2.442LeuPhe: 2.442 ± 0.058	9.548LeuGly: 9.548 ± 0.088	1.813LeuHis: 1.813 ± 0.043	2.344LeuIle: 2.344 ± 0.053	1.296LeuLys: 1.296 ± 0.037	10.574LeuLeu: 10.574 ± 0.134	1.486LeuMet: 1.486 ± 0.039	1.393LeuAsn: 1.393 ± 0.037	5.668LeuPro: 5.668 ± 0.07	2.2LeuGln: 2.2 ± 0.041	7.578LeuArg: 7.578 ± 0.101	5.894LeuSer: 5.894 ± 0.077	7.043LeuThr: 7.043 ± 0.077	11.878LeuVal: 11.878 ± 0.131	1.218LeuTrp: 1.218 ± 0.037	1.519LeuTyr: 1.519 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	1.936MetAla: 1.936 ± 0.041	0.087MetCys: 0.087 ± 0.007	0.814MetAsp: 0.814 ± 0.025	0.591MetGlu: 0.591 ± 0.022	0.475MetPhe: 0.475 ± 0.022	1.145MetGly: 1.145 ± 0.032	0.307MetHis: 0.307 ± 0.015	0.717MetIle: 0.717 ± 0.021	0.317MetLys: 0.317 ± 0.019	1.842MetLeu: 1.842 ± 0.046	0.277MetMet: 0.277 ± 0.016	0.35MetAsn: 0.35 ± 0.016	0.955MetPro: 0.955 ± 0.026	0.418MetGln: 0.418 ± 0.019	1.157MetArg: 1.157 ± 0.031	1.411MetSer: 1.411 ± 0.03	1.772MetThr: 1.772 ± 0.036	1.424MetVal: 1.424 ± 0.033	0.182MetTrp: 0.182 ± 0.013	0.252MetTyr: 0.252 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	1.8AsnAla: 1.8 ± 0.038	0.071AsnCys: 0.071 ± 0.007	0.878AsnAsp: 0.878 ± 0.03	0.744AsnGlu: 0.744 ± 0.026	0.483AsnPhe: 0.483 ± 0.021	1.426AsnGly: 1.426 ± 0.038	0.33AsnHis: 0.33 ± 0.016	0.621AsnIle: 0.621 ± 0.027	0.275AsnLys: 0.275 ± 0.015	1.68AsnLeu: 1.68 ± 0.04	0.232AsnMet: 0.232 ± 0.014	0.332AsnAsn: 0.332 ± 0.017	1.211AsnPro: 1.211 ± 0.036	0.451AsnGln: 0.451 ± 0.021	0.989AsnArg: 0.989 ± 0.03	0.757AsnSer: 0.757 ± 0.028	0.89AsnThr: 0.89 ± 0.031	1.43AsnVal: 1.43 ± 0.036	0.181AsnTrp: 0.181 ± 0.012	0.333AsnTyr: 0.333 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	8.273ProAla: 8.273 ± 0.122	0.204ProCys: 0.204 ± 0.013	4.199ProAsp: 4.199 ± 0.063	4.032ProGlu: 4.032 ± 0.066	1.456ProPhe: 1.456 ± 0.032	6.0ProGly: 6.0 ± 0.102	1.1ProHis: 1.1 ± 0.031	1.25ProIle: 1.25 ± 0.036	0.748ProLys: 0.748 ± 0.032	4.898ProLeu: 4.898 ± 0.066	0.768ProMet: 0.768 ± 0.025	0.693ProAsn: 0.693 ± 0.026	2.639ProPro: 2.639 ± 0.063	1.641ProGln: 1.641 ± 0.041	3.568ProArg: 3.568 ± 0.064	3.772ProSer: 3.772 ± 0.07	4.303ProThr: 4.303 ± 0.077	6.028ProVal: 6.028 ± 0.093	0.87ProTrp: 0.87 ± 0.027	0.903ProTyr: 0.903 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	3.725GlnAla: 3.725 ± 0.067	0.123GlnCys: 0.123 ± 0.012	1.508GlnAsp: 1.508 ± 0.034	1.255GlnGlu: 1.255 ± 0.034	0.632GlnPhe: 0.632 ± 0.025	2.263GlnGly: 2.263 ± 0.048	0.699GlnHis: 0.699 ± 0.022	1.138GlnIle: 1.138 ± 0.033	0.478GlnLys: 0.478 ± 0.019	2.772GlnLeu: 2.772 ± 0.053	0.53GlnMet: 0.53 ± 0.022	0.512GlnAsn: 0.512 ± 0.024	1.77GlnPro: 1.77 ± 0.043	1.3GlnGln: 1.3 ± 0.045	2.161GlnArg: 2.161 ± 0.053	1.428GlnSer: 1.428 ± 0.034	1.897GlnThr: 1.897 ± 0.046	3.219GlnVal: 3.219 ± 0.054	0.408GlnTrp: 0.408 ± 0.022	0.544GlnTyr: 0.544 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.919ArgAla: 8.919 ± 0.102	0.384ArgCys: 0.384 ± 0.018	4.178ArgAsp: 4.178 ± 0.059	4.021ArgGlu: 4.021 ± 0.076	1.942ArgPhe: 1.942 ± 0.041	5.368ArgGly: 5.368 ± 0.078	1.478ArgHis: 1.478 ± 0.038	2.345ArgIle: 2.345 ± 0.048	1.131ArgLys: 1.131 ± 0.033	7.459ArgLeu: 7.459 ± 0.088	1.459ArgMet: 1.459 ± 0.035	1.001ArgAsn: 1.001 ± 0.03	4.11ArgPro: 4.11 ± 0.073	1.978ArgGln: 1.978 ± 0.045	6.714ArgArg: 6.714 ± 0.104	4.794ArgSer: 4.794 ± 0.072	5.163ArgThr: 5.163 ± 0.07	5.947ArgVal: 5.947 ± 0.071	1.329ArgTrp: 1.329 ± 0.037	1.5ArgTyr: 1.5 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	7.851SerAla: 7.851 ± 0.097	0.303SerCys: 0.303 ± 0.016	3.445SerAsp: 3.445 ± 0.068	2.894SerGlu: 2.894 ± 0.047	1.687SerPhe: 1.687 ± 0.036	6.249SerGly: 6.249 ± 0.09	1.048SerHis: 1.048 ± 0.029	2.087SerIle: 2.087 ± 0.044	0.921SerLys: 0.921 ± 0.029	5.4SerLeu: 5.4 ± 0.073	1.196SerMet: 1.196 ± 0.033	0.863SerAsn: 0.863 ± 0.027	3.516SerPro: 3.516 ± 0.06	1.595SerGln: 1.595 ± 0.039	4.079SerArg: 4.079 ± 0.071	4.048SerSer: 4.048 ± 0.068	5.021SerThr: 5.021 ± 0.073	5.422SerVal: 5.422 ± 0.067	0.994SerTrp: 0.994 ± 0.028	1.168SerTyr: 1.168 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	8.999ThrAla: 8.999 ± 0.111	0.327ThrCys: 0.327 ± 0.018	4.249ThrAsp: 4.249 ± 0.072	3.48ThrGlu: 3.48 ± 0.056	2.058ThrPhe: 2.058 ± 0.042	6.802ThrGly: 6.802 ± 0.096	1.238ThrHis: 1.238 ± 0.032	2.276ThrIle: 2.276 ± 0.053	0.938ThrLys: 0.938 ± 0.031	6.664ThrLeu: 6.664 ± 0.083	1.038ThrMet: 1.038 ± 0.029	1.063ThrAsn: 1.063 ± 0.032	4.418ThrPro: 4.418 ± 0.081	1.695ThrGln: 1.695 ± 0.042	3.889ThrArg: 3.889 ± 0.056	4.734ThrSer: 4.734 ± 0.071	5.673ThrThr: 5.673 ± 0.098	7.843ThrVal: 7.843 ± 0.131	1.102ThrTrp: 1.102 ± 0.036	1.381ThrTyr: 1.381 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	13.695ValAla: 13.695 ± 0.131	0.578ValCys: 0.578 ± 0.019	7.342ValAsp: 7.342 ± 0.089	5.938ValGlu: 5.938 ± 0.073	2.499ValPhe: 2.499 ± 0.046	8.29ValGly: 8.29 ± 0.108	1.923ValHis: 1.923 ± 0.044	2.932ValIle: 2.932 ± 0.064	1.348ValLys: 1.348 ± 0.041	11.182ValLeu: 11.182 ± 0.135	1.511ValMet: 1.511 ± 0.039	1.541ValAsn: 1.541 ± 0.037	5.725ValPro: 5.725 ± 0.089	2.441ValGln: 2.441 ± 0.046	7.037ValArg: 7.037 ± 0.084	5.704ValSer: 5.704 ± 0.07	6.971ValThr: 6.971 ± 0.137	12.559ValVal: 12.559 ± 0.148	1.234ValTrp: 1.234 ± 0.033	1.574ValTyr: 1.574 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.618TrpAla: 1.618 ± 0.037	0.113TrpCys: 0.113 ± 0.009	0.9TrpAsp: 0.9 ± 0.03	0.684TrpGlu: 0.684 ± 0.024	0.517TrpPhe: 0.517 ± 0.023	1.076TrpGly: 1.076 ± 0.032	0.33TrpHis: 0.33 ± 0.018	0.433TrpIle: 0.433 ± 0.02	0.25TrpLys: 0.25 ± 0.015	1.554TrpLeu: 1.554 ± 0.043	0.288TrpMet: 0.288 ± 0.015	0.299TrpAsn: 0.299 ± 0.018	0.697TrpPro: 0.697 ± 0.023	0.498TrpGln: 0.498 ± 0.018	1.107TrpArg: 1.107 ± 0.033	1.043TrpSer: 1.043 ± 0.031	1.095TrpThr: 1.095 ± 0.032	1.306TrpVal: 1.306 ± 0.034	0.371TrpTrp: 0.371 ± 0.02	0.3TrpTyr: 0.3 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.26TyrAla: 2.26 ± 0.038	0.097TyrCys: 0.097 ± 0.008	1.256TyrAsp: 1.256 ± 0.035	1.048TyrGlu: 1.048 ± 0.032	0.549TyrPhe: 0.549 ± 0.02	1.762TyrGly: 1.762 ± 0.046	0.264TyrHis: 0.264 ± 0.014	0.391TyrIle: 0.391 ± 0.018	0.258TyrLys: 0.258 ± 0.015	2.117TyrLeu: 2.117 ± 0.047	0.219TyrMet: 0.219 ± 0.013	0.334TyrAsn: 0.334 ± 0.019	0.945TyrPro: 0.945 ± 0.03	0.555TyrGln: 0.555 ± 0.021	1.399TyrArg: 1.399 ± 0.036	1.094TyrSer: 1.094 ± 0.035	1.185TyrThr: 1.185 ± 0.038	1.773TyrVal: 1.773 ± 0.039	0.294TyrTrp: 0.294 ± 0.017	0.415TyrTyr: 0.415 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3710 proteins (1274206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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