Amino acid dipepetide frequency for Aurantimonas sp. 22II-16-19i

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.96AlaAla: 19.96 ± 0.183	1.075AlaCys: 1.075 ± 0.027	7.43AlaAsp: 7.43 ± 0.076	8.773AlaGlu: 8.773 ± 0.086	4.779AlaPhe: 4.779 ± 0.06	12.599AlaGly: 12.599 ± 0.108	2.069AlaHis: 2.069 ± 0.036	7.224AlaIle: 7.224 ± 0.08	3.878AlaLys: 3.878 ± 0.056	13.237AlaLeu: 13.237 ± 0.119	3.861AlaMet: 3.861 ± 0.053	2.789AlaAsn: 2.789 ± 0.045	5.905AlaPro: 5.905 ± 0.087	3.155AlaGln: 3.155 ± 0.057	9.254AlaArg: 9.254 ± 0.093	7.203AlaSer: 7.203 ± 0.079	6.469AlaThr: 6.469 ± 0.064	9.349AlaVal: 9.349 ± 0.081	1.34AlaTrp: 1.34 ± 0.028	2.518AlaTyr: 2.518 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.872CysAla: 0.872 ± 0.024	0.082CysCys: 0.082 ± 0.008	0.52CysAsp: 0.52 ± 0.015	0.438CysGlu: 0.438 ± 0.019	0.289CysPhe: 0.289 ± 0.014	0.966CysGly: 0.966 ± 0.026	0.237CysHis: 0.237 ± 0.014	0.328CysIle: 0.328 ± 0.013	0.147CysLys: 0.147 ± 0.009	0.834CysLeu: 0.834 ± 0.024	0.152CysMet: 0.152 ± 0.011	0.169CysAsn: 0.169 ± 0.011	0.406CysPro: 0.406 ± 0.016	0.213CysGln: 0.213 ± 0.014	0.7CysArg: 0.7 ± 0.025	0.378CysSer: 0.378 ± 0.015	0.329CysThr: 0.329 ± 0.015	0.563CysVal: 0.563 ± 0.018	0.1CysTrp: 0.1 ± 0.009	0.157CysTyr: 0.157 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	7.491AspAla: 7.491 ± 0.076	0.473AspCys: 0.473 ± 0.019	3.444AspAsp: 3.444 ± 0.058	3.865AspGlu: 3.865 ± 0.058	2.243AspPhe: 2.243 ± 0.04	5.925AspGly: 5.925 ± 0.081	1.285AspHis: 1.285 ± 0.033	2.805AspIle: 2.805 ± 0.042	1.579AspLys: 1.579 ± 0.033	6.08AspLeu: 6.08 ± 0.068	1.313AspMet: 1.313 ± 0.031	1.148AspAsn: 1.148 ± 0.032	3.681AspPro: 3.681 ± 0.048	1.643AspGln: 1.643 ± 0.033	4.722AspArg: 4.722 ± 0.06	1.93AspSer: 1.93 ± 0.035	2.726AspThr: 2.726 ± 0.056	4.348AspVal: 4.348 ± 0.055	0.902AspTrp: 0.902 ± 0.028	1.452AspTyr: 1.452 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	9.244GluAla: 9.244 ± 0.086	0.33GluCys: 0.33 ± 0.014	3.139GluAsp: 3.139 ± 0.052	3.487GluGlu: 3.487 ± 0.053	1.682GluPhe: 1.682 ± 0.036	4.722GluGly: 4.722 ± 0.061	1.058GluHis: 1.058 ± 0.027	3.755GluIle: 3.755 ± 0.051	2.158GluLys: 2.158 ± 0.04	5.054GluLeu: 5.054 ± 0.059	1.669GluMet: 1.669 ± 0.036	1.506GluAsn: 1.506 ± 0.035	3.068GluPro: 3.068 ± 0.056	1.616GluGln: 1.616 ± 0.034	5.558GluArg: 5.558 ± 0.071	2.357GluSer: 2.357 ± 0.041	4.223GluThr: 4.223 ± 0.054	3.812GluVal: 3.812 ± 0.053	0.702GluTrp: 0.702 ± 0.025	0.898GluTyr: 0.898 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	5.032PheAla: 5.032 ± 0.057	0.385PheCys: 0.385 ± 0.015	2.728PheAsp: 2.728 ± 0.047	2.31PheGlu: 2.31 ± 0.037	1.467PhePhe: 1.467 ± 0.037	3.815PheGly: 3.815 ± 0.057	0.715PheHis: 0.715 ± 0.021	1.474PheIle: 1.474 ± 0.034	0.858PheLys: 0.858 ± 0.025	3.587PheLeu: 3.587 ± 0.045	0.757PheMet: 0.757 ± 0.024	0.872PheAsn: 0.872 ± 0.028	1.564PhePro: 1.564 ± 0.032	0.993PheGln: 0.993 ± 0.024	2.316PheArg: 2.316 ± 0.039	2.246PheSer: 2.246 ± 0.035	1.882PheThr: 1.882 ± 0.036	3.151PheVal: 3.151 ± 0.054	0.492PheTrp: 0.492 ± 0.019	0.878PheTyr: 0.878 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	10.267GlyAla: 10.267 ± 0.101	0.824GlyCys: 0.824 ± 0.022	5.207GlyAsp: 5.207 ± 0.085	5.905GlyGlu: 5.905 ± 0.073	3.845GlyPhe: 3.845 ± 0.056	8.285GlyGly: 8.285 ± 0.15	1.908GlyHis: 1.908 ± 0.037	4.632GlyIle: 4.632 ± 0.063	2.862GlyLys: 2.862 ± 0.048	9.052GlyLeu: 9.052 ± 0.092	2.313GlyMet: 2.313 ± 0.039	2.168GlyAsn: 2.168 ± 0.067	3.751GlyPro: 3.751 ± 0.048	2.647GlyGln: 2.647 ± 0.042	6.98GlyArg: 6.98 ± 0.075	5.158GlySer: 5.158 ± 0.064	4.969GlyThr: 4.969 ± 0.071	6.088GlyVal: 6.088 ± 0.061	1.324GlyTrp: 1.324 ± 0.029	2.184GlyTyr: 2.184 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.169HisAla: 2.169 ± 0.04	0.222HisCys: 0.222 ± 0.012	1.168HisAsp: 1.168 ± 0.027	0.993HisGlu: 0.993 ± 0.026	0.758HisPhe: 0.758 ± 0.023	1.886HisGly: 1.886 ± 0.04	0.504HisHis: 0.504 ± 0.024	0.719HisIle: 0.719 ± 0.021	0.369HisLys: 0.369 ± 0.013	2.002HisLeu: 2.002 ± 0.031	0.418HisMet: 0.418 ± 0.017	0.34HisAsn: 0.34 ± 0.013	1.28HisPro: 1.28 ± 0.029	0.561HisGln: 0.561 ± 0.018	1.442HisArg: 1.442 ± 0.038	0.842HisSer: 0.842 ± 0.022	0.674HisThr: 0.674 ± 0.022	1.499HisVal: 1.499 ± 0.029	0.27HisTrp: 0.27 ± 0.015	0.481HisTyr: 0.481 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	7.717IleAla: 7.717 ± 0.078	0.463IleCys: 0.463 ± 0.017	3.706IleAsp: 3.706 ± 0.051	3.586IleGlu: 3.586 ± 0.046	1.733IlePhe: 1.733 ± 0.035	5.03IleGly: 5.03 ± 0.058	0.827IleHis: 0.827 ± 0.023	1.9IleIle: 1.9 ± 0.041	1.119IleLys: 1.119 ± 0.026	4.578IleLeu: 4.578 ± 0.069	0.835IleMet: 0.835 ± 0.021	1.137IleAsn: 1.137 ± 0.03	2.184IlePro: 2.184 ± 0.04	1.075IleGln: 1.075 ± 0.028	3.379IleArg: 3.379 ± 0.049	2.536IleSer: 2.536 ± 0.043	2.523IleThr: 2.523 ± 0.047	4.593IleVal: 4.593 ± 0.058	0.53IleTrp: 0.53 ± 0.018	0.998IleTyr: 0.998 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	4.14LysAla: 4.14 ± 0.055	0.125LysCys: 0.125 ± 0.009	1.587LysAsp: 1.587 ± 0.038	1.389LysGlu: 1.389 ± 0.029	0.711LysPhe: 0.711 ± 0.024	2.508LysGly: 2.508 ± 0.05	0.456LysHis: 0.456 ± 0.016	1.519LysIle: 1.519 ± 0.03	1.003LysLys: 1.003 ± 0.029	2.816LysLeu: 2.816 ± 0.043	0.669LysMet: 0.669 ± 0.022	0.728LysAsn: 0.728 ± 0.021	1.81LysPro: 1.81 ± 0.035	0.785LysGln: 0.785 ± 0.021	2.279LysArg: 2.279 ± 0.039	1.594LysSer: 1.594 ± 0.032	1.856LysThr: 1.856 ± 0.039	2.16LysVal: 2.16 ± 0.043	0.278LysTrp: 0.278 ± 0.012	0.484LysTyr: 0.484 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	14.647LeuAla: 14.647 ± 0.135	0.897LeuCys: 0.897 ± 0.024	5.98LeuAsp: 5.98 ± 0.068	5.035LeuGlu: 5.035 ± 0.054	3.676LeuPhe: 3.676 ± 0.064	8.299LeuGly: 8.299 ± 0.072	1.551LeuHis: 1.551 ± 0.031	4.587LeuIle: 4.587 ± 0.051	3.418LeuLys: 3.418 ± 0.046	8.867LeuLeu: 8.867 ± 0.095	2.201LeuMet: 2.201 ± 0.037	2.128LeuAsn: 2.128 ± 0.048	5.265LeuPro: 5.265 ± 0.067	2.547LeuGln: 2.547 ± 0.045	6.39LeuArg: 6.39 ± 0.075	6.565LeuSer: 6.565 ± 0.073	5.449LeuThr: 5.449 ± 0.067	7.949LeuVal: 7.949 ± 0.085	1.081LeuTrp: 1.081 ± 0.026	1.934LeuTyr: 1.934 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	3.225MetAla: 3.225 ± 0.042	0.117MetCys: 0.117 ± 0.008	1.07MetAsp: 1.07 ± 0.025	1.166MetGlu: 1.166 ± 0.03	0.656MetPhe: 0.656 ± 0.021	1.737MetGly: 1.737 ± 0.031	0.391MetHis: 0.391 ± 0.014	1.405MetIle: 1.405 ± 0.03	0.952MetLys: 0.952 ± 0.027	2.401MetLeu: 2.401 ± 0.044	0.654MetMet: 0.654 ± 0.022	0.736MetAsn: 0.736 ± 0.02	1.585MetPro: 1.585 ± 0.035	0.746MetGln: 0.746 ± 0.022	1.906MetArg: 1.906 ± 0.034	1.619MetSer: 1.619 ± 0.03	1.877MetThr: 1.877 ± 0.036	1.635MetVal: 1.635 ± 0.032	0.171MetTrp: 0.171 ± 0.011	0.284MetTyr: 0.284 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.999AsnAla: 2.999 ± 0.046	0.196AsnCys: 0.196 ± 0.011	1.408AsnAsp: 1.408 ± 0.045	1.14AsnGlu: 1.14 ± 0.031	0.852AsnPhe: 0.852 ± 0.025	2.319AsnGly: 2.319 ± 0.051	0.429AsnHis: 0.429 ± 0.015	1.027AsnIle: 1.027 ± 0.026	0.498AsnLys: 0.498 ± 0.018	2.283AsnLeu: 2.283 ± 0.042	0.526AsnMet: 0.526 ± 0.019	0.534AsnAsn: 0.534 ± 0.022	1.579AsnPro: 1.579 ± 0.03	0.659AsnGln: 0.659 ± 0.021	1.672AsnArg: 1.672 ± 0.036	1.056AsnSer: 1.056 ± 0.031	1.05AsnThr: 1.05 ± 0.031	1.806AsnVal: 1.806 ± 0.039	0.345AsnTrp: 0.345 ± 0.014	0.568AsnTyr: 0.568 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	7.071ProAla: 7.071 ± 0.089	0.296ProCys: 0.296 ± 0.013	3.658ProAsp: 3.658 ± 0.055	3.794ProGlu: 3.794 ± 0.05	2.005ProPhe: 2.005 ± 0.036	4.805ProGly: 4.805 ± 0.058	0.987ProHis: 0.987 ± 0.021	2.367ProIle: 2.367 ± 0.042	1.583ProLys: 1.583 ± 0.036	4.719ProLeu: 4.719 ± 0.064	1.195ProMet: 1.195 ± 0.03	1.196ProAsn: 1.196 ± 0.027	2.488ProPro: 2.488 ± 0.05	1.673ProGln: 1.673 ± 0.035	3.093ProArg: 3.093 ± 0.046	2.868ProSer: 2.868 ± 0.041	2.398ProThr: 2.398 ± 0.04	4.124ProVal: 4.124 ± 0.059	0.572ProTrp: 0.572 ± 0.018	1.152ProTyr: 1.152 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.694GlnAla: 3.694 ± 0.059	0.179GlnCys: 0.179 ± 0.012	1.402GlnAsp: 1.402 ± 0.027	1.414GlnGlu: 1.414 ± 0.034	0.941GlnPhe: 0.941 ± 0.023	2.092GlnGly: 2.092 ± 0.035	0.514GlnHis: 0.514 ± 0.021	1.705GlnIle: 1.705 ± 0.033	0.904GlnLys: 0.904 ± 0.024	2.474GlnLeu: 2.474 ± 0.043	0.835GlnMet: 0.835 ± 0.027	0.748GlnAsn: 0.748 ± 0.024	1.681GlnPro: 1.681 ± 0.036	0.995GlnGln: 0.995 ± 0.034	2.237GlnArg: 2.237 ± 0.043	1.669GlnSer: 1.669 ± 0.031	1.661GlnThr: 1.661 ± 0.033	1.902GlnVal: 1.902 ± 0.036	0.343GlnTrp: 0.343 ± 0.016	0.519GlnTyr: 0.519 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	7.995ArgAla: 7.995 ± 0.089	0.516ArgCys: 0.516 ± 0.02	4.232ArgAsp: 4.232 ± 0.056	4.489ArgGlu: 4.489 ± 0.053	3.14ArgPhe: 3.14 ± 0.049	5.124ArgGly: 5.124 ± 0.062	1.772ArgHis: 1.772 ± 0.035	4.131ArgIle: 4.131 ± 0.053	2.032ArgLys: 2.032 ± 0.038	8.441ArgLeu: 8.441 ± 0.091	1.912ArgMet: 1.912 ± 0.034	1.673ArgAsn: 1.673 ± 0.029	4.124ArgPro: 4.124 ± 0.062	2.726ArgGln: 2.726 ± 0.041	6.691ArgArg: 6.691 ± 0.092	4.085ArgSer: 4.085 ± 0.059	3.371ArgThr: 3.371 ± 0.049	4.529ArgVal: 4.529 ± 0.053	0.931ArgTrp: 0.931 ± 0.025	1.635ArgTyr: 1.635 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	6.413SerAla: 6.413 ± 0.075	0.407SerCys: 0.407 ± 0.016	3.078SerAsp: 3.078 ± 0.047	3.017SerGlu: 3.017 ± 0.047	2.367SerPhe: 2.367 ± 0.037	6.032SerGly: 6.032 ± 0.079	1.02SerHis: 1.02 ± 0.025	2.699SerIle: 2.699 ± 0.04	1.335SerLys: 1.335 ± 0.03	5.561SerLeu: 5.561 ± 0.069	1.254SerMet: 1.254 ± 0.027	1.244SerAsn: 1.244 ± 0.029	2.917SerPro: 2.917 ± 0.042	1.665SerGln: 1.665 ± 0.034	3.884SerArg: 3.884 ± 0.053	2.964SerSer: 2.964 ± 0.052	2.563SerThr: 2.563 ± 0.043	3.968SerVal: 3.968 ± 0.054	0.684SerTrp: 0.684 ± 0.02	1.219SerTyr: 1.219 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.488ThrAla: 6.488 ± 0.066	0.369ThrCys: 0.369 ± 0.016	2.835ThrAsp: 2.835 ± 0.047	2.603ThrGlu: 2.603 ± 0.044	2.052ThrPhe: 2.052 ± 0.038	5.442ThrGly: 5.442 ± 0.073	0.888ThrHis: 0.888 ± 0.021	3.246ThrIle: 3.246 ± 0.05	1.282ThrLys: 1.282 ± 0.029	5.675ThrLeu: 5.675 ± 0.051	1.257ThrMet: 1.257 ± 0.027	1.188ThrAsn: 1.188 ± 0.026	3.136ThrPro: 3.136 ± 0.047	1.277ThrGln: 1.277 ± 0.03	3.374ThrArg: 3.374 ± 0.047	2.892ThrSer: 2.892 ± 0.051	2.832ThrThr: 2.832 ± 0.047	4.584ThrVal: 4.584 ± 0.064	0.572ThrTrp: 0.572 ± 0.021	1.162ThrTyr: 1.162 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	9.988ValAla: 9.988 ± 0.087	0.595ValCys: 0.595 ± 0.02	4.417ValAsp: 4.417 ± 0.056	4.92ValGlu: 4.92 ± 0.064	2.991ValPhe: 2.991 ± 0.05	5.882ValGly: 5.882 ± 0.072	1.291ValHis: 1.291 ± 0.028	3.616ValIle: 3.616 ± 0.052	2.057ValLys: 2.057 ± 0.044	7.155ValLeu: 7.155 ± 0.082	1.823ValMet: 1.823 ± 0.036	1.747ValAsn: 1.747 ± 0.034	3.9ValPro: 3.9 ± 0.051	1.703ValGln: 1.703 ± 0.033	4.83ValArg: 4.83 ± 0.062	4.496ValSer: 4.496 ± 0.057	4.578ValThr: 4.578 ± 0.061	6.362ValVal: 6.362 ± 0.067	0.891ValTrp: 0.891 ± 0.027	1.502ValTyr: 1.502 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.067TrpAla: 1.067 ± 0.025	0.124TrpCys: 0.124 ± 0.009	0.575TrpAsp: 0.575 ± 0.017	0.522TrpGlu: 0.522 ± 0.02	0.483TrpPhe: 0.483 ± 0.016	0.794TrpGly: 0.794 ± 0.027	0.294TrpHis: 0.294 ± 0.014	0.615TrpIle: 0.615 ± 0.02	0.371TrpLys: 0.371 ± 0.016	1.523TrpLeu: 1.523 ± 0.032	0.31TrpMet: 0.31 ± 0.014	0.398TrpAsn: 0.398 ± 0.015	0.663TrpPro: 0.663 ± 0.02	0.539TrpGln: 0.539 ± 0.02	1.074TrpArg: 1.074 ± 0.024	0.796TrpSer: 0.796 ± 0.023	0.721TrpThr: 0.721 ± 0.019	0.704TrpVal: 0.704 ± 0.02	0.21TrpTrp: 0.21 ± 0.013	0.266TrpTyr: 0.266 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.387TyrAla: 2.387 ± 0.038	0.205TyrCys: 0.205 ± 0.011	1.469TyrAsp: 1.469 ± 0.032	1.191TyrGlu: 1.191 ± 0.025	0.851TyrPhe: 0.851 ± 0.023	2.108TyrGly: 2.108 ± 0.039	0.403TyrHis: 0.403 ± 0.016	0.696TyrIle: 0.696 ± 0.022	0.495TyrLys: 0.495 ± 0.021	2.132TyrLeu: 2.132 ± 0.043	0.376TyrMet: 0.376 ± 0.017	0.496TyrAsn: 0.496 ± 0.021	1.054TyrPro: 1.054 ± 0.024	0.691TyrGln: 0.691 ± 0.021	1.768TyrArg: 1.768 ± 0.037	1.038TyrSer: 1.038 ± 0.028	1.0TyrThr: 1.0 ± 0.028	1.618TyrVal: 1.618 ± 0.031	0.31TyrTrp: 0.31 ± 0.016	0.548TyrTyr: 0.548 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5291 proteins (1651721 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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