Amino acid dipepetide frequency for Prevotella veroralis F0319

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.22AlaAla: 5.22 ± 0.103
0.865AlaCys: 0.865 ± 0.034
4.0AlaAsp: 4.0 ± 0.077
4.185AlaGlu: 4.185 ± 0.083
3.062AlaPhe: 3.062 ± 0.07
4.497AlaGly: 4.497 ± 0.097
1.401AlaHis: 1.401 ± 0.048
4.783AlaIle: 4.783 ± 0.085
4.747AlaLys: 4.747 ± 0.08
6.455AlaLeu: 6.455 ± 0.108
2.124AlaMet: 2.124 ± 0.052
3.404AlaAsn: 3.404 ± 0.065
2.177AlaPro: 2.177 ± 0.052
2.898AlaGln: 2.898 ± 0.061
2.972AlaArg: 2.972 ± 0.066
4.177AlaSer: 4.177 ± 0.076
3.808AlaThr: 3.808 ± 0.072
4.359AlaVal: 4.359 ± 0.066
0.744AlaTrp: 0.744 ± 0.028
3.078AlaTyr: 3.078 ± 0.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.747CysAla: 0.747 ± 0.029
0.208CysCys: 0.208 ± 0.018
0.691CysAsp: 0.691 ± 0.03
0.642CysGlu: 0.642 ± 0.028
0.634CysPhe: 0.634 ± 0.029
0.907CysGly: 0.907 ± 0.038
0.334CysHis: 0.334 ± 0.023
0.918CysIle: 0.918 ± 0.035
0.817CysLys: 0.817 ± 0.033
1.125CysLeu: 1.125 ± 0.038
0.313CysMet: 0.313 ± 0.02
0.619CysAsn: 0.619 ± 0.028
0.731CysPro: 0.731 ± 0.032
0.408CysGln: 0.408 ± 0.023
0.592CysArg: 0.592 ± 0.025
0.829CysSer: 0.829 ± 0.034
0.644CysThr: 0.644 ± 0.031
0.709CysVal: 0.709 ± 0.029
0.159CysTrp: 0.159 ± 0.013
0.58CysTyr: 0.58 ± 0.025
0.0CysXaa: 0.0 ± 0.0
Asp
3.929AspAla: 3.929 ± 0.083
0.647AspCys: 0.647 ± 0.033
3.084AspAsp: 3.084 ± 0.067
3.837AspGlu: 3.837 ± 0.067
2.934AspPhe: 2.934 ± 0.068
4.082AspGly: 4.082 ± 0.074
0.995AspHis: 0.995 ± 0.029
4.2AspIle: 4.2 ± 0.075
4.464AspLys: 4.464 ± 0.08
4.396AspLeu: 4.396 ± 0.075
1.55AspMet: 1.55 ± 0.039
3.243AspAsn: 3.243 ± 0.073
1.885AspPro: 1.885 ± 0.05
1.345AspGln: 1.345 ± 0.041
2.454AspArg: 2.454 ± 0.057
3.135AspSer: 3.135 ± 0.068
2.701AspThr: 2.701 ± 0.057
3.691AspVal: 3.691 ± 0.065
0.731AspTrp: 0.731 ± 0.03
2.942AspTyr: 2.942 ± 0.061
0.0AspXaa: 0.0 ± 0.0
Glu
4.49GluAla: 4.49 ± 0.079
0.647GluCys: 0.647 ± 0.027
3.225GluAsp: 3.225 ± 0.066
4.788GluGlu: 4.788 ± 0.096
2.231GluPhe: 2.231 ± 0.053
3.935GluGly: 3.935 ± 0.078
1.431GluHis: 1.431 ± 0.044
3.846GluIle: 3.846 ± 0.074
4.515GluLys: 4.515 ± 0.077
5.526GluLeu: 5.526 ± 0.093
1.842GluMet: 1.842 ± 0.048
2.966GluAsn: 2.966 ± 0.062
1.754GluPro: 1.754 ± 0.047
2.821GluGln: 2.821 ± 0.062
3.539GluArg: 3.539 ± 0.067
2.986GluSer: 2.986 ± 0.06
3.159GluThr: 3.159 ± 0.068
3.9GluVal: 3.9 ± 0.066
0.705GluTrp: 0.705 ± 0.029
2.515GluTyr: 2.515 ± 0.056
0.0GluXaa: 0.0 ± 0.0
Phe
2.953PheAla: 2.953 ± 0.064
0.682PheCys: 0.682 ± 0.027
2.685PheAsp: 2.685 ± 0.065
2.158PheGlu: 2.158 ± 0.055
2.195PhePhe: 2.195 ± 0.067
3.015PheGly: 3.015 ± 0.069
1.065PheHis: 1.065 ± 0.038
3.24PheIle: 3.24 ± 0.071
2.625PheLys: 2.625 ± 0.06
3.914PheLeu: 3.914 ± 0.076
1.213PheMet: 1.213 ± 0.039
2.297PheAsn: 2.297 ± 0.058
1.611PhePro: 1.611 ± 0.048
1.251PheGln: 1.251 ± 0.038
2.089PheArg: 2.089 ± 0.047
3.221PheSer: 3.221 ± 0.077
2.8PheThr: 2.8 ± 0.064
2.866PheVal: 2.866 ± 0.059
0.455PheTrp: 0.455 ± 0.024
1.975PheTyr: 1.975 ± 0.05
0.0PheXaa: 0.0 ± 0.0
Gly
4.182GlyAla: 4.182 ± 0.089
0.86GlyCys: 0.86 ± 0.034
3.385GlyAsp: 3.385 ± 0.072
3.775GlyGlu: 3.775 ± 0.064
2.941GlyPhe: 2.941 ± 0.06
4.427GlyGly: 4.427 ± 0.1
1.374GlyHis: 1.374 ± 0.041
4.644GlyIle: 4.644 ± 0.077
5.431GlyLys: 5.431 ± 0.082
5.5GlyLeu: 5.5 ± 0.093
1.946GlyMet: 1.946 ± 0.051
3.32GlyAsn: 3.32 ± 0.07
1.047GlyPro: 1.047 ± 0.035
2.338GlyGln: 2.338 ± 0.061
3.135GlyArg: 3.135 ± 0.072
3.952GlySer: 3.952 ± 0.078
4.053GlyThr: 4.053 ± 0.074
4.81GlyVal: 4.81 ± 0.08
0.904GlyTrp: 0.904 ± 0.035
3.118GlyTyr: 3.118 ± 0.064
0.0GlyXaa: 0.0 ± 0.0
His
1.278HisAla: 1.278 ± 0.043
0.362HisCys: 0.362 ± 0.021
1.089HisAsp: 1.089 ± 0.033
1.124HisGlu: 1.124 ± 0.038
1.143HisPhe: 1.143 ± 0.042
1.343HisGly: 1.343 ± 0.038
0.623HisHis: 0.623 ± 0.035
1.691HisIle: 1.691 ± 0.048
1.358HisLys: 1.358 ± 0.041
2.07HisLeu: 2.07 ± 0.046
0.433HisMet: 0.433 ± 0.02
1.11HisAsn: 1.11 ± 0.036
1.123HisPro: 1.123 ± 0.043
0.888HisGln: 0.888 ± 0.032
1.161HisArg: 1.161 ± 0.036
1.35HisSer: 1.35 ± 0.038
1.157HisThr: 1.157 ± 0.036
1.221HisVal: 1.221 ± 0.044
0.249HisTrp: 0.249 ± 0.019
1.104HisTyr: 1.104 ± 0.038
0.0HisXaa: 0.0 ± 0.0
Ile
5.18IleAla: 5.18 ± 0.095
0.891IleCys: 0.891 ± 0.033
4.611IleAsp: 4.611 ± 0.076
4.369IleGlu: 4.369 ± 0.063
2.647IlePhe: 2.647 ± 0.058
4.423IleGly: 4.423 ± 0.084
1.431IleHis: 1.431 ± 0.045
4.871IleIle: 4.871 ± 0.087
4.392IleLys: 4.392 ± 0.069
5.764IleLeu: 5.764 ± 0.094
1.622IleMet: 1.622 ± 0.044
3.719IleAsn: 3.719 ± 0.084
2.935IlePro: 2.935 ± 0.064
2.262IleGln: 2.262 ± 0.046
3.164IleArg: 3.164 ± 0.06
4.384IleSer: 4.384 ± 0.064
4.195IleThr: 4.195 ± 0.071
4.412IleVal: 4.412 ± 0.078
0.536IleTrp: 0.536 ± 0.029
2.645IleTyr: 2.645 ± 0.052
0.0IleXaa: 0.0 ± 0.0
Lys
5.443LysAla: 5.443 ± 0.085
0.604LysCys: 0.604 ± 0.03
4.295LysAsp: 4.295 ± 0.083
5.67LysGlu: 5.67 ± 0.092
2.218LysPhe: 2.218 ± 0.05
4.642LysGly: 4.642 ± 0.079
1.427LysHis: 1.427 ± 0.044
4.052LysIle: 4.052 ± 0.061
5.334LysLys: 5.334 ± 0.093
5.634LysLeu: 5.634 ± 0.074
2.188LysMet: 2.188 ± 0.049
3.412LysAsn: 3.412 ± 0.069
2.472LysPro: 2.472 ± 0.053
3.087LysGln: 3.087 ± 0.058
3.758LysArg: 3.758 ± 0.074
3.701LysSer: 3.701 ± 0.064
3.802LysThr: 3.802 ± 0.067
4.74LysVal: 4.74 ± 0.084
0.826LysTrp: 0.826 ± 0.032
2.949LysTyr: 2.949 ± 0.064
0.0LysXaa: 0.0 ± 0.0
Leu
5.968LeuAla: 5.968 ± 0.089
1.367LeuCys: 1.367 ± 0.044
4.664LeuAsp: 4.664 ± 0.074
4.5LeuGlu: 4.5 ± 0.081
4.388LeuPhe: 4.388 ± 0.093
5.466LeuGly: 5.466 ± 0.1
2.123LeuHis: 2.123 ± 0.051
5.53LeuIle: 5.53 ± 0.091
6.077LeuLys: 6.077 ± 0.082
9.08LeuLeu: 9.08 ± 0.152
2.674LeuMet: 2.674 ± 0.055
4.512LeuAsn: 4.512 ± 0.078
3.941LeuPro: 3.941 ± 0.063
3.616LeuGln: 3.616 ± 0.067
4.481LeuArg: 4.481 ± 0.093
6.981LeuSer: 6.981 ± 0.111
5.474LeuThr: 5.474 ± 0.086
5.204LeuVal: 5.204 ± 0.083
1.045LeuTrp: 1.045 ± 0.04
3.81LeuTyr: 3.81 ± 0.068
0.0LeuXaa: 0.0 ± 0.0
Met
2.062MetAla: 2.062 ± 0.046
0.265MetCys: 0.265 ± 0.017
1.507MetAsp: 1.507 ± 0.042
1.826MetGlu: 1.826 ± 0.05
0.989MetPhe: 0.989 ± 0.031
1.969MetGly: 1.969 ± 0.045
0.506MetHis: 0.506 ± 0.024
1.675MetIle: 1.675 ± 0.046
2.646MetLys: 2.646 ± 0.057
2.502MetLeu: 2.502 ± 0.056
0.9MetMet: 0.9 ± 0.028
1.619MetAsn: 1.619 ± 0.033
1.118MetPro: 1.118 ± 0.037
1.08MetGln: 1.08 ± 0.034
1.463MetArg: 1.463 ± 0.042
1.65MetSer: 1.65 ± 0.041
1.703MetThr: 1.703 ± 0.041
1.628MetVal: 1.628 ± 0.043
0.225MetTrp: 0.225 ± 0.017
0.773MetTyr: 0.773 ± 0.034
0.0MetXaa: 0.0 ± 0.0
Asn
3.489AsnAla: 3.489 ± 0.067
0.485AsnCys: 0.485 ± 0.02
2.853AsnAsp: 2.853 ± 0.065
2.824AsnGlu: 2.824 ± 0.06
2.203AsnPhe: 2.203 ± 0.049
3.891AsnGly: 3.891 ± 0.089
1.15AsnHis: 1.15 ± 0.034
3.931AsnIle: 3.931 ± 0.083
3.583AsnLys: 3.583 ± 0.076
4.326AsnLeu: 4.326 ± 0.081
1.309AsnMet: 1.309 ± 0.043
2.884AsnAsn: 2.884 ± 0.075
2.337AsnPro: 2.337 ± 0.049
1.758AsnGln: 1.758 ± 0.041
2.639AsnArg: 2.639 ± 0.06
2.902AsnSer: 2.902 ± 0.073
2.771AsnThr: 2.771 ± 0.066
3.269AsnVal: 3.269 ± 0.06
0.57AsnTrp: 0.57 ± 0.026
2.373AsnTyr: 2.373 ± 0.052
0.0AsnXaa: 0.0 ± 0.0
Pro
2.454ProAla: 2.454 ± 0.059
0.37ProCys: 0.37 ± 0.024
2.161ProAsp: 2.161 ± 0.046
2.6ProGlu: 2.6 ± 0.06
1.87ProPhe: 1.87 ± 0.048
1.827ProGly: 1.827 ± 0.051
0.844ProHis: 0.844 ± 0.035
2.374ProIle: 2.374 ± 0.048
2.337ProLys: 2.337 ± 0.055
3.34ProLeu: 3.34 ± 0.063
1.014ProMet: 1.014 ± 0.038
1.978ProAsn: 1.978 ± 0.048
0.862ProPro: 0.862 ± 0.037
1.561ProGln: 1.561 ± 0.036
1.458ProArg: 1.458 ± 0.046
2.565ProSer: 2.565 ± 0.052
2.38ProThr: 2.38 ± 0.051
2.517ProVal: 2.517 ± 0.055
0.399ProTrp: 0.399 ± 0.022
1.791ProTyr: 1.791 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
2.639GlnAla: 2.639 ± 0.056
0.339GlnCys: 0.339 ± 0.02
1.716GlnAsp: 1.716 ± 0.047
2.261GlnGlu: 2.261 ± 0.054
1.435GlnPhe: 1.435 ± 0.038
2.309GlnGly: 2.309 ± 0.058
0.983GlnHis: 0.983 ± 0.032
2.409GlnIle: 2.409 ± 0.059
2.667GlnLys: 2.667 ± 0.057
3.797GlnLeu: 3.797 ± 0.077
1.151GlnMet: 1.151 ± 0.038
1.665GlnAsn: 1.665 ± 0.046
1.451GlnPro: 1.451 ± 0.048
1.978GlnGln: 1.978 ± 0.054
2.11GlnArg: 2.11 ± 0.049
2.106GlnSer: 2.106 ± 0.045
2.183GlnThr: 2.183 ± 0.043
2.227GlnVal: 2.227 ± 0.044
0.525GlnTrp: 0.525 ± 0.022
1.562GlnTyr: 1.562 ± 0.045
0.0GlnXaa: 0.0 ± 0.0
Arg
2.892ArgAla: 2.892 ± 0.059
0.659ArgCys: 0.659 ± 0.028
2.358ArgAsp: 2.358 ± 0.055
2.958ArgGlu: 2.958 ± 0.07
2.208ArgPhe: 2.208 ± 0.047
2.757ArgGly: 2.757 ± 0.066
1.103ArgHis: 1.103 ± 0.037
3.482ArgIle: 3.482 ± 0.065
3.576ArgLys: 3.576 ± 0.063
4.818ArgLeu: 4.818 ± 0.084
1.635ArgMet: 1.635 ± 0.048
2.602ArgAsn: 2.602 ± 0.054
1.676ArgPro: 1.676 ± 0.05
2.064ArgGln: 2.064 ± 0.054
2.722ArgArg: 2.722 ± 0.064
2.578ArgSer: 2.578 ± 0.056
2.685ArgThr: 2.685 ± 0.059
2.732ArgVal: 2.732 ± 0.059
0.597ArgTrp: 0.597 ± 0.025
2.438ArgTyr: 2.438 ± 0.058
0.0ArgXaa: 0.0 ± 0.0
Ser
3.926SerAla: 3.926 ± 0.068
0.903SerCys: 0.903 ± 0.035
3.287SerAsp: 3.287 ± 0.067
3.311SerGlu: 3.311 ± 0.063
3.279SerPhe: 3.279 ± 0.061
3.768SerGly: 3.768 ± 0.072
1.316SerHis: 1.316 ± 0.042
4.464SerIle: 4.464 ± 0.074
4.021SerLys: 4.021 ± 0.069
6.537SerLeu: 6.537 ± 0.102
1.586SerMet: 1.586 ± 0.051
2.99SerAsn: 2.99 ± 0.072
2.324SerPro: 2.324 ± 0.05
2.067SerGln: 2.067 ± 0.05
2.687SerArg: 2.687 ± 0.065
4.202SerSer: 4.202 ± 0.078
3.391SerThr: 3.391 ± 0.063
4.163SerVal: 4.163 ± 0.076
0.767SerTrp: 0.767 ± 0.031
2.903SerTyr: 2.903 ± 0.069
0.0SerXaa: 0.0 ± 0.0
Thr
4.076ThrAla: 4.076 ± 0.073
0.651ThrCys: 0.651 ± 0.028
3.559ThrAsp: 3.559 ± 0.065
3.263ThrGlu: 3.263 ± 0.06
2.696ThrPhe: 2.696 ± 0.058
3.993ThrGly: 3.993 ± 0.082
1.224ThrHis: 1.224 ± 0.036
4.322ThrIle: 4.322 ± 0.074
3.533ThrLys: 3.533 ± 0.072
5.575ThrLeu: 5.575 ± 0.075
1.38ThrMet: 1.38 ± 0.04
2.687ThrAsn: 2.687 ± 0.059
2.87ThrPro: 2.87 ± 0.062
1.888ThrGln: 1.888 ± 0.05
2.191ThrArg: 2.191 ± 0.045
3.576ThrSer: 3.576 ± 0.065
3.432ThrThr: 3.432 ± 0.082
3.13ThrVal: 3.13 ± 0.065
0.638ThrTrp: 0.638 ± 0.025
2.523ThrTyr: 2.523 ± 0.065
0.0ThrXaa: 0.0 ± 0.0
Val
4.435ValAla: 4.435 ± 0.081
1.09ValCys: 1.09 ± 0.034
3.68ValAsp: 3.68 ± 0.062
3.766ValGlu: 3.766 ± 0.069
2.657ValPhe: 2.657 ± 0.06
4.081ValGly: 4.081 ± 0.076
1.172ValHis: 1.172 ± 0.04
4.293ValIle: 4.293 ± 0.08
4.217ValLys: 4.217 ± 0.075
5.496ValLeu: 5.496 ± 0.09
1.719ValMet: 1.719 ± 0.048
3.211ValAsn: 3.211 ± 0.068
2.471ValPro: 2.471 ± 0.052
2.045ValGln: 2.045 ± 0.051
3.163ValArg: 3.163 ± 0.061
4.291ValSer: 4.291 ± 0.07
3.706ValThr: 3.706 ± 0.068
4.362ValVal: 4.362 ± 0.08
0.697ValTrp: 0.697 ± 0.025
2.574ValTyr: 2.574 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.703TrpAla: 0.703 ± 0.031
0.148TrpCys: 0.148 ± 0.015
0.678TrpAsp: 0.678 ± 0.032
0.659TrpGlu: 0.659 ± 0.03
0.535TrpPhe: 0.535 ± 0.029
0.829TrpGly: 0.829 ± 0.033
0.255TrpHis: 0.255 ± 0.019
0.747TrpIle: 0.747 ± 0.031
0.916TrpLys: 0.916 ± 0.033
1.189TrpLeu: 1.189 ± 0.043
0.35TrpMet: 0.35 ± 0.02
0.695TrpAsn: 0.695 ± 0.03
0.187TrpPro: 0.187 ± 0.016
0.541TrpGln: 0.541 ± 0.026
0.581TrpArg: 0.581 ± 0.025
0.609TrpSer: 0.609 ± 0.028
0.596TrpThr: 0.596 ± 0.022
0.657TrpVal: 0.657 ± 0.027
0.171TrpTrp: 0.171 ± 0.016
0.468TrpTyr: 0.468 ± 0.023
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.887TyrAla: 2.887 ± 0.054
0.564TyrCys: 0.564 ± 0.024
2.717TyrAsp: 2.717 ± 0.068
2.308TyrGlu: 2.308 ± 0.054
2.043TyrPhe: 2.043 ± 0.046
2.983TyrGly: 2.983 ± 0.065
1.119TyrHis: 1.119 ± 0.037
2.983TyrIle: 2.983 ± 0.066
2.995TyrLys: 2.995 ± 0.06
3.858TyrLeu: 3.858 ± 0.076
1.156TyrMet: 1.156 ± 0.035
2.615TyrAsn: 2.615 ± 0.058
1.729TyrPro: 1.729 ± 0.05
1.619TyrGln: 1.619 ± 0.043
2.178TyrArg: 2.178 ± 0.052
2.699TyrSer: 2.699 ± 0.06
2.568TyrThr: 2.568 ± 0.066
2.528TyrVal: 2.528 ± 0.054
0.57TyrTrp: 0.57 ± 0.027
2.176TyrTyr: 2.176 ± 0.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3037 proteins (859322 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski