Amino acid dipepetide frequency for Acinetobacter virus 133

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.966AlaAla: 4.966 ± 0.404
0.394AlaCys: 0.394 ± 0.105
3.429AlaAsp: 3.429 ± 0.237
4.217AlaGlu: 4.217 ± 0.319
2.404AlaPhe: 2.404 ± 0.202
4.434AlaGly: 4.434 ± 0.461
1.064AlaHis: 1.064 ± 0.14
5.675AlaIle: 5.675 ± 0.353
4.729AlaLys: 4.729 ± 0.325
5.872AlaLeu: 5.872 ± 0.395
1.576AlaMet: 1.576 ± 0.195
3.567AlaAsn: 3.567 ± 0.311
2.463AlaPro: 2.463 ± 0.262
2.66AlaGln: 2.66 ± 0.209
3.409AlaArg: 3.409 ± 0.218
4.276AlaSer: 4.276 ± 0.336
4.237AlaThr: 4.237 ± 0.47
4.158AlaVal: 4.158 ± 0.302
0.887AlaTrp: 0.887 ± 0.131
2.345AlaTyr: 2.345 ± 0.231
0.0AlaXaa: 0.0 ± 0.0
Cys
0.729CysAla: 0.729 ± 0.135
0.079CysCys: 0.079 ± 0.037
0.749CysAsp: 0.749 ± 0.128
0.709CysGlu: 0.709 ± 0.118
0.453CysPhe: 0.453 ± 0.088
0.729CysGly: 0.729 ± 0.127
0.315CysHis: 0.315 ± 0.092
0.828CysIle: 0.828 ± 0.151
0.828CysLys: 0.828 ± 0.136
1.044CysLeu: 1.044 ± 0.136
0.335CysMet: 0.335 ± 0.08
0.67CysAsn: 0.67 ± 0.12
0.631CysPro: 0.631 ± 0.122
0.355CysGln: 0.355 ± 0.076
0.473CysArg: 0.473 ± 0.094
0.749CysSer: 0.749 ± 0.101
0.906CysThr: 0.906 ± 0.129
0.69CysVal: 0.69 ± 0.126
0.138CysTrp: 0.138 ± 0.051
0.473CysTyr: 0.473 ± 0.102
0.0CysXaa: 0.0 ± 0.0
Asp
4.118AspAla: 4.118 ± 0.289
0.67AspCys: 0.67 ± 0.103
3.527AspAsp: 3.527 ± 0.384
3.665AspGlu: 3.665 ± 0.273
2.68AspPhe: 2.68 ± 0.227
4.059AspGly: 4.059 ± 0.246
1.34AspHis: 1.34 ± 0.184
4.453AspIle: 4.453 ± 0.306
4.316AspLys: 4.316 ± 0.272
5.656AspLeu: 5.656 ± 0.393
1.714AspMet: 1.714 ± 0.18
2.838AspAsn: 2.838 ± 0.228
2.916AspPro: 2.916 ± 0.27
2.483AspGln: 2.483 ± 0.191
2.227AspArg: 2.227 ± 0.183
3.429AspSer: 3.429 ± 0.234
3.448AspThr: 3.448 ± 0.24
4.099AspVal: 4.099 ± 0.342
1.025AspTrp: 1.025 ± 0.173
2.719AspTyr: 2.719 ± 0.238
0.0AspXaa: 0.0 ± 0.0
Glu
4.02GluAla: 4.02 ± 0.36
0.926GluCys: 0.926 ± 0.14
2.916GluAsp: 2.916 ± 0.264
3.33GluGlu: 3.33 ± 0.307
2.818GluPhe: 2.818 ± 0.211
3.133GluGly: 3.133 ± 0.263
1.32GluHis: 1.32 ± 0.184
4.414GluIle: 4.414 ± 0.316
3.705GluLys: 3.705 ± 0.265
6.739GluLeu: 6.739 ± 0.434
2.089GluMet: 2.089 ± 0.223
3.133GluAsn: 3.133 ± 0.213
2.03GluPro: 2.03 ± 0.224
2.7GluGln: 2.7 ± 0.257
2.483GluArg: 2.483 ± 0.241
4.118GluSer: 4.118 ± 0.293
3.626GluThr: 3.626 ± 0.314
4.414GluVal: 4.414 ± 0.276
0.749GluTrp: 0.749 ± 0.121
3.488GluTyr: 3.488 ± 0.265
0.0GluXaa: 0.0 ± 0.0
Phe
2.621PheAla: 2.621 ± 0.273
0.453PheCys: 0.453 ± 0.087
3.271PheAsp: 3.271 ± 0.256
2.641PheGlu: 2.641 ± 0.222
1.439PhePhe: 1.439 ± 0.197
2.936PheGly: 2.936 ± 0.235
0.729PheHis: 0.729 ± 0.122
3.113PheIle: 3.113 ± 0.256
3.33PheLys: 3.33 ± 0.281
2.818PheLeu: 2.818 ± 0.257
1.182PheMet: 1.182 ± 0.125
2.818PheAsn: 2.818 ± 0.226
1.379PhePro: 1.379 ± 0.154
1.281PheGln: 1.281 ± 0.158
1.498PheArg: 1.498 ± 0.167
2.207PheSer: 2.207 ± 0.206
2.384PheThr: 2.384 ± 0.214
2.838PheVal: 2.838 ± 0.262
0.512PheTrp: 0.512 ± 0.095
1.655PheTyr: 1.655 ± 0.204
0.0PheXaa: 0.0 ± 0.0
Gly
3.783GlyAla: 3.783 ± 0.407
0.69GlyCys: 0.69 ± 0.092
3.882GlyAsp: 3.882 ± 0.296
3.37GlyGlu: 3.37 ± 0.305
2.424GlyPhe: 2.424 ± 0.203
3.389GlyGly: 3.389 ± 0.448
1.34GlyHis: 1.34 ± 0.185
3.882GlyIle: 3.882 ± 0.287
4.138GlyLys: 4.138 ± 0.36
5.163GlyLeu: 5.163 ± 0.344
1.99GlyMet: 1.99 ± 0.19
3.232GlyAsn: 3.232 ± 0.298
1.971GlyPro: 1.971 ± 0.205
2.66GlyGln: 2.66 ± 0.244
2.68GlyArg: 2.68 ± 0.24
3.685GlySer: 3.685 ± 0.321
4.591GlyThr: 4.591 ± 0.516
4.513GlyVal: 4.513 ± 0.333
1.005GlyTrp: 1.005 ± 0.135
2.719GlyTyr: 2.719 ± 0.212
0.0GlyXaa: 0.0 ± 0.0
His
1.222HisAla: 1.222 ± 0.149
0.571HisCys: 0.571 ± 0.116
1.241HisAsp: 1.241 ± 0.155
1.281HisGlu: 1.281 ± 0.156
1.044HisPhe: 1.044 ± 0.136
1.517HisGly: 1.517 ± 0.176
0.591HisHis: 0.591 ± 0.111
1.517HisIle: 1.517 ± 0.18
1.32HisLys: 1.32 ± 0.15
1.833HisLeu: 1.833 ± 0.184
0.67HisMet: 0.67 ± 0.138
1.163HisAsn: 1.163 ± 0.137
1.163HisPro: 1.163 ± 0.151
0.985HisGln: 0.985 ± 0.138
0.828HisArg: 0.828 ± 0.131
1.379HisSer: 1.379 ± 0.175
1.202HisThr: 1.202 ± 0.175
1.36HisVal: 1.36 ± 0.163
0.374HisTrp: 0.374 ± 0.082
0.65HisTyr: 0.65 ± 0.11
0.0HisXaa: 0.0 ± 0.0
Ile
4.788IleAla: 4.788 ± 0.34
0.867IleCys: 0.867 ± 0.129
4.591IleAsp: 4.591 ± 0.303
5.222IleGlu: 5.222 ± 0.366
2.069IlePhe: 2.069 ± 0.202
3.744IleGly: 3.744 ± 0.27
1.517IleHis: 1.517 ± 0.19
4.296IleIle: 4.296 ± 0.314
5.951IleLys: 5.951 ± 0.42
5.045IleLeu: 5.045 ± 0.31
1.852IleMet: 1.852 ± 0.16
4.237IleAsn: 4.237 ± 0.282
2.562IlePro: 2.562 ± 0.258
3.291IleGln: 3.291 ± 0.239
3.271IleArg: 3.271 ± 0.269
3.961IleSer: 3.961 ± 0.277
4.335IleThr: 4.335 ± 0.383
4.808IleVal: 4.808 ± 0.316
0.887IleTrp: 0.887 ± 0.134
2.207IleTyr: 2.207 ± 0.238
0.0IleXaa: 0.0 ± 0.0
Lys
4.828LysAla: 4.828 ± 0.315
0.769LysCys: 0.769 ± 0.11
3.882LysAsp: 3.882 ± 0.322
4.02LysGlu: 4.02 ± 0.341
3.606LysPhe: 3.606 ± 0.264
3.882LysGly: 3.882 ± 0.252
1.833LysHis: 1.833 ± 0.192
4.69LysIle: 4.69 ± 0.318
3.409LysLys: 3.409 ± 0.251
5.892LysLeu: 5.892 ± 0.358
2.483LysMet: 2.483 ± 0.239
3.311LysAsn: 3.311 ± 0.266
2.719LysPro: 2.719 ± 0.26
2.483LysGln: 2.483 ± 0.238
3.173LysArg: 3.173 ± 0.246
4.532LysSer: 4.532 ± 0.368
4.394LysThr: 4.394 ± 0.296
4.828LysVal: 4.828 ± 0.371
0.966LysTrp: 0.966 ± 0.12
3.271LysTyr: 3.271 ± 0.257
0.0LysXaa: 0.0 ± 0.0
Leu
5.498LeuAla: 5.498 ± 0.345
1.084LeuCys: 1.084 ± 0.159
5.853LeuAsp: 5.853 ± 0.359
5.695LeuGlu: 5.695 ± 0.344
3.567LeuPhe: 3.567 ± 0.293
4.394LeuGly: 4.394 ± 0.321
1.852LeuHis: 1.852 ± 0.196
4.946LeuIle: 4.946 ± 0.305
6.128LeuLys: 6.128 ± 0.382
5.399LeuLeu: 5.399 ± 0.424
2.66LeuMet: 2.66 ± 0.26
5.242LeuAsn: 5.242 ± 0.372
3.291LeuPro: 3.291 ± 0.248
3.251LeuGln: 3.251 ± 0.265
3.685LeuArg: 3.685 ± 0.228
5.222LeuSer: 5.222 ± 0.311
5.833LeuThr: 5.833 ± 0.362
4.907LeuVal: 4.907 ± 0.301
0.788LeuTrp: 0.788 ± 0.133
3.173LeuTyr: 3.173 ± 0.235
0.0LeuXaa: 0.0 ± 0.0
Met
2.187MetAla: 2.187 ± 0.217
0.355MetCys: 0.355 ± 0.085
1.695MetAsp: 1.695 ± 0.199
1.478MetGlu: 1.478 ± 0.179
1.34MetPhe: 1.34 ± 0.183
1.596MetGly: 1.596 ± 0.168
0.69MetHis: 0.69 ± 0.118
1.852MetIle: 1.852 ± 0.165
2.266MetLys: 2.266 ± 0.208
2.266MetLeu: 2.266 ± 0.2
0.749MetMet: 0.749 ± 0.119
1.636MetAsn: 1.636 ± 0.192
0.867MetPro: 0.867 ± 0.148
1.36MetGln: 1.36 ± 0.185
1.202MetArg: 1.202 ± 0.16
2.365MetSer: 2.365 ± 0.226
1.793MetThr: 1.793 ± 0.161
1.774MetVal: 1.774 ± 0.159
0.315MetTrp: 0.315 ± 0.08
1.261MetTyr: 1.261 ± 0.173
0.0MetXaa: 0.0 ± 0.0
Asn
3.981AsnAla: 3.981 ± 0.288
0.69AsnCys: 0.69 ± 0.124
2.621AsnAsp: 2.621 ± 0.197
3.646AsnGlu: 3.646 ± 0.256
2.01AsnPhe: 2.01 ± 0.164
3.724AsnGly: 3.724 ± 0.355
1.281AsnHis: 1.281 ± 0.169
3.961AsnIle: 3.961 ± 0.272
3.488AsnLys: 3.488 ± 0.279
4.572AsnLeu: 4.572 ± 0.248
1.793AsnMet: 1.793 ± 0.171
3.488AsnAsn: 3.488 ± 0.279
2.66AsnPro: 2.66 ± 0.234
2.03AsnGln: 2.03 ± 0.19
2.503AsnArg: 2.503 ± 0.217
2.976AsnSer: 2.976 ± 0.232
3.468AsnThr: 3.468 ± 0.335
3.744AsnVal: 3.744 ± 0.286
0.867AsnTrp: 0.867 ± 0.152
1.971AsnTyr: 1.971 ± 0.186
0.0AsnXaa: 0.0 ± 0.0
Pro
2.562ProAla: 2.562 ± 0.247
0.512ProCys: 0.512 ± 0.11
3.054ProAsp: 3.054 ± 0.231
2.838ProGlu: 2.838 ± 0.272
1.557ProPhe: 1.557 ± 0.194
2.818ProGly: 2.818 ± 0.251
0.867ProHis: 0.867 ± 0.134
2.542ProIle: 2.542 ± 0.267
2.246ProLys: 2.246 ± 0.241
2.818ProLeu: 2.818 ± 0.219
0.926ProMet: 0.926 ± 0.135
2.089ProAsn: 2.089 ± 0.221
1.222ProPro: 1.222 ± 0.132
1.005ProGln: 1.005 ± 0.155
1.34ProArg: 1.34 ± 0.166
2.325ProSer: 2.325 ± 0.218
2.168ProThr: 2.168 ± 0.233
3.33ProVal: 3.33 ± 0.283
0.532ProTrp: 0.532 ± 0.123
1.498ProTyr: 1.498 ± 0.17
0.0ProXaa: 0.0 ± 0.0
Gln
2.759GlnAla: 2.759 ± 0.275
0.394GlnCys: 0.394 ± 0.099
2.207GlnAsp: 2.207 ± 0.203
2.384GlnGlu: 2.384 ± 0.215
1.793GlnPhe: 1.793 ± 0.221
2.345GlnGly: 2.345 ± 0.239
0.749GlnHis: 0.749 ± 0.113
2.897GlnIle: 2.897 ± 0.244
2.246GlnLys: 2.246 ± 0.224
3.705GlnLeu: 3.705 ± 0.314
1.281GlnMet: 1.281 ± 0.145
1.931GlnAsn: 1.931 ± 0.182
1.281GlnPro: 1.281 ± 0.172
1.163GlnGln: 1.163 ± 0.149
1.911GlnArg: 1.911 ± 0.202
2.365GlnSer: 2.365 ± 0.175
2.542GlnThr: 2.542 ± 0.213
2.838GlnVal: 2.838 ± 0.221
0.611GlnTrp: 0.611 ± 0.092
2.03GlnTyr: 2.03 ± 0.217
0.0GlnXaa: 0.0 ± 0.0
Arg
3.015ArgAla: 3.015 ± 0.274
0.374ArgCys: 0.374 ± 0.094
2.877ArgAsp: 2.877 ± 0.192
2.838ArgGlu: 2.838 ± 0.271
1.793ArgPhe: 1.793 ± 0.158
2.424ArgGly: 2.424 ± 0.236
1.104ArgHis: 1.104 ± 0.156
3.646ArgIle: 3.646 ± 0.24
3.35ArgLys: 3.35 ± 0.248
3.665ArgLeu: 3.665 ± 0.255
1.379ArgMet: 1.379 ± 0.168
2.7ArgAsn: 2.7 ± 0.249
1.281ArgPro: 1.281 ± 0.163
1.636ArgGln: 1.636 ± 0.19
1.734ArgArg: 1.734 ± 0.191
2.483ArgSer: 2.483 ± 0.235
2.759ArgThr: 2.759 ± 0.213
2.897ArgVal: 2.897 ± 0.241
0.631ArgTrp: 0.631 ± 0.125
2.069ArgTyr: 2.069 ± 0.17
0.0ArgXaa: 0.0 ± 0.0
Ser
4.02SerAla: 4.02 ± 0.315
0.788SerCys: 0.788 ± 0.131
3.409SerAsp: 3.409 ± 0.245
3.173SerGlu: 3.173 ± 0.257
2.483SerPhe: 2.483 ± 0.198
4.217SerGly: 4.217 ± 0.354
1.399SerHis: 1.399 ± 0.169
4.493SerIle: 4.493 ± 0.356
4.749SerLys: 4.749 ± 0.325
5.478SerLeu: 5.478 ± 0.367
1.675SerMet: 1.675 ± 0.185
3.646SerAsn: 3.646 ± 0.26
2.148SerPro: 2.148 ± 0.229
2.108SerGln: 2.108 ± 0.193
3.094SerArg: 3.094 ± 0.246
3.646SerSer: 3.646 ± 0.342
3.665SerThr: 3.665 ± 0.293
4.059SerVal: 4.059 ± 0.246
0.788SerTrp: 0.788 ± 0.13
2.384SerTyr: 2.384 ± 0.222
0.0SerXaa: 0.0 ± 0.0
Thr
3.961ThrAla: 3.961 ± 0.524
0.591ThrCys: 0.591 ± 0.115
3.862ThrAsp: 3.862 ± 0.28
4.04ThrGlu: 4.04 ± 0.294
2.522ThrPhe: 2.522 ± 0.233
4.651ThrGly: 4.651 ± 0.467
1.241ThrHis: 1.241 ± 0.14
4.808ThrIle: 4.808 ± 0.345
3.685ThrLys: 3.685 ± 0.278
5.222ThrLeu: 5.222 ± 0.317
1.478ThrMet: 1.478 ± 0.149
3.33ThrAsn: 3.33 ± 0.242
2.897ThrPro: 2.897 ± 0.294
2.66ThrGln: 2.66 ± 0.244
3.015ThrArg: 3.015 ± 0.247
3.508ThrSer: 3.508 ± 0.303
3.547ThrThr: 3.547 ± 0.329
4.532ThrVal: 4.532 ± 0.377
0.67ThrTrp: 0.67 ± 0.111
2.286ThrTyr: 2.286 ± 0.237
0.0ThrXaa: 0.0 ± 0.0
Val
4.414ValAla: 4.414 ± 0.303
1.025ValCys: 1.025 ± 0.137
4.71ValAsp: 4.71 ± 0.262
4.591ValGlu: 4.591 ± 0.347
2.641ValPhe: 2.641 ± 0.221
3.803ValGly: 3.803 ± 0.328
1.439ValHis: 1.439 ± 0.172
4.02ValIle: 4.02 ± 0.312
5.498ValLys: 5.498 ± 0.342
5.183ValLeu: 5.183 ± 0.312
1.714ValMet: 1.714 ± 0.183
3.291ValAsn: 3.291 ± 0.247
2.562ValPro: 2.562 ± 0.223
3.192ValGln: 3.192 ± 0.277
3.468ValArg: 3.468 ± 0.272
4.296ValSer: 4.296 ± 0.333
4.276ValThr: 4.276 ± 0.299
4.0ValVal: 4.0 ± 0.309
0.847ValTrp: 0.847 ± 0.13
2.818ValTyr: 2.818 ± 0.251
0.0ValXaa: 0.0 ± 0.0
Trp
0.906TrpAla: 0.906 ± 0.127
0.118TrpCys: 0.118 ± 0.052
1.163TrpAsp: 1.163 ± 0.144
0.808TrpGlu: 0.808 ± 0.117
0.493TrpPhe: 0.493 ± 0.08
0.65TrpGly: 0.65 ± 0.121
0.236TrpHis: 0.236 ± 0.061
0.847TrpIle: 0.847 ± 0.133
0.847TrpLys: 0.847 ± 0.126
0.946TrpLeu: 0.946 ± 0.13
0.355TrpMet: 0.355 ± 0.076
0.729TrpAsn: 0.729 ± 0.107
0.473TrpPro: 0.473 ± 0.098
0.532TrpGln: 0.532 ± 0.093
0.591TrpArg: 0.591 ± 0.12
1.005TrpSer: 1.005 ± 0.124
0.788TrpThr: 0.788 ± 0.111
1.123TrpVal: 1.123 ± 0.136
0.197TrpTrp: 0.197 ± 0.065
0.473TrpTyr: 0.473 ± 0.086
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.404TyrAla: 2.404 ± 0.235
0.532TyrCys: 0.532 ± 0.122
2.443TyrAsp: 2.443 ± 0.229
2.207TyrGlu: 2.207 ± 0.2
1.971TyrPhe: 1.971 ± 0.212
2.66TyrGly: 2.66 ± 0.234
1.005TyrHis: 1.005 ± 0.138
2.621TyrIle: 2.621 ± 0.208
2.739TyrLys: 2.739 ± 0.233
3.153TyrLeu: 3.153 ± 0.29
1.123TyrMet: 1.123 ± 0.14
2.424TyrAsn: 2.424 ± 0.211
1.734TyrPro: 1.734 ± 0.188
1.596TyrGln: 1.596 ± 0.202
2.069TyrArg: 2.069 ± 0.191
2.897TyrSer: 2.897 ± 0.243
2.542TyrThr: 2.542 ± 0.234
2.877TyrVal: 2.877 ± 0.274
0.493TyrTrp: 0.493 ± 0.084
1.419TyrTyr: 1.419 ± 0.161
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 257 proteins (50748 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski