Amino acid dipepetide frequency for Sinimarinibacterium flocculans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.435AlaAla: 18.435 ± 0.189	1.381AlaCys: 1.381 ± 0.034	7.551AlaAsp: 7.551 ± 0.078	7.453AlaGlu: 7.453 ± 0.09	3.917AlaPhe: 3.917 ± 0.057	10.94AlaGly: 10.94 ± 0.11	2.612AlaHis: 2.612 ± 0.046	5.109AlaIle: 5.109 ± 0.075	2.823AlaLys: 2.823 ± 0.056	14.684AlaLeu: 14.684 ± 0.151	3.037AlaMet: 3.037 ± 0.051	2.462AlaAsn: 2.462 ± 0.055	6.366AlaPro: 6.366 ± 0.085	5.312AlaGln: 5.312 ± 0.078	10.371AlaArg: 10.371 ± 0.113	5.945AlaSer: 5.945 ± 0.064	5.81AlaThr: 5.81 ± 0.074	9.076AlaVal: 9.076 ± 0.091	1.885AlaTrp: 1.885 ± 0.038	2.675AlaTyr: 2.675 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	1.367CysAla: 1.367 ± 0.029	0.125CysCys: 0.125 ± 0.011	0.562CysAsp: 0.562 ± 0.02	0.54CysGlu: 0.54 ± 0.019	0.319CysPhe: 0.319 ± 0.016	1.101CysGly: 1.101 ± 0.03	0.266CysHis: 0.266 ± 0.018	0.394CysIle: 0.394 ± 0.017	0.207CysLys: 0.207 ± 0.013	0.867CysLeu: 0.867 ± 0.025	0.162CysMet: 0.162 ± 0.012	0.255CysAsn: 0.255 ± 0.016	0.487CysPro: 0.487 ± 0.024	0.234CysGln: 0.234 ± 0.014	0.733CysArg: 0.733 ± 0.025	0.53CysSer: 0.53 ± 0.021	0.484CysThr: 0.484 ± 0.02	0.738CysVal: 0.738 ± 0.026	0.135CysTrp: 0.135 ± 0.01	0.216CysTyr: 0.216 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	8.607AspAla: 8.607 ± 0.104	0.579AspCys: 0.579 ± 0.02	3.84AspAsp: 3.84 ± 0.069	3.793AspGlu: 3.793 ± 0.056	2.197AspPhe: 2.197 ± 0.043	6.176AspGly: 6.176 ± 0.085	1.163AspHis: 1.163 ± 0.031	2.505AspIle: 2.505 ± 0.045	1.361AspLys: 1.361 ± 0.04	5.821AspLeu: 5.821 ± 0.07	1.016AspMet: 1.016 ± 0.028	1.244AspAsn: 1.244 ± 0.03	3.667AspPro: 3.667 ± 0.05	1.566AspGln: 1.566 ± 0.035	4.309AspArg: 4.309 ± 0.054	2.393AspSer: 2.393 ± 0.05	2.769AspThr: 2.769 ± 0.045	4.226AspVal: 4.226 ± 0.064	1.057AspTrp: 1.057 ± 0.031	1.753AspTyr: 1.753 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	7.192GluAla: 7.192 ± 0.073	0.421GluCys: 0.421 ± 0.018	2.7GluAsp: 2.7 ± 0.044	2.445GluGlu: 2.445 ± 0.055	1.82GluPhe: 1.82 ± 0.038	3.679GluGly: 3.679 ± 0.057	1.403GluHis: 1.403 ± 0.034	2.899GluIle: 2.899 ± 0.048	1.537GluLys: 1.537 ± 0.04	6.324GluLeu: 6.324 ± 0.076	1.183GluMet: 1.183 ± 0.03	1.303GluAsn: 1.303 ± 0.038	2.894GluPro: 2.894 ± 0.053	2.802GluGln: 2.802 ± 0.054	5.796GluArg: 5.796 ± 0.081	2.773GluSer: 2.773 ± 0.054	2.943GluThr: 2.943 ± 0.05	4.01GluVal: 4.01 ± 0.062	0.722GluTrp: 0.722 ± 0.025	1.222GluTyr: 1.222 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	4.34PheAla: 4.34 ± 0.066	0.389PheCys: 0.389 ± 0.015	2.782PheAsp: 2.782 ± 0.05	2.267PheGlu: 2.267 ± 0.038	1.284PhePhe: 1.284 ± 0.037	3.491PheGly: 3.491 ± 0.063	0.716PheHis: 0.716 ± 0.023	1.332PheIle: 1.332 ± 0.034	0.884PheLys: 0.884 ± 0.03	2.861PheLeu: 2.861 ± 0.049	0.69PheMet: 0.69 ± 0.024	0.995PheAsn: 0.995 ± 0.028	1.486PhePro: 1.486 ± 0.033	0.891PheGln: 0.891 ± 0.024	2.206PheArg: 2.206 ± 0.044	1.95PheSer: 1.95 ± 0.046	1.769PheThr: 1.769 ± 0.04	2.777PheVal: 2.777 ± 0.049	0.481PheTrp: 0.481 ± 0.02	0.87PheTyr: 0.87 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	9.456GlyAla: 9.456 ± 0.104	0.969GlyCys: 0.969 ± 0.031	4.951GlyAsp: 4.951 ± 0.065	5.003GlyGlu: 5.003 ± 0.069	3.423GlyPhe: 3.423 ± 0.055	7.526GlyGly: 7.526 ± 0.098	1.873GlyHis: 1.873 ± 0.04	4.111GlyIle: 4.111 ± 0.056	2.413GlyLys: 2.413 ± 0.054	8.886GlyLeu: 8.886 ± 0.109	2.08GlyMet: 2.08 ± 0.039	2.079GlyAsn: 2.079 ± 0.043	3.309GlyPro: 3.309 ± 0.049	2.837GlyGln: 2.837 ± 0.052	6.505GlyArg: 6.505 ± 0.067	4.605GlySer: 4.605 ± 0.061	4.489GlyThr: 4.489 ± 0.06	6.549GlyVal: 6.549 ± 0.072	1.513GlyTrp: 1.513 ± 0.039	2.449GlyTyr: 2.449 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.864HisAla: 2.864 ± 0.045	0.267HisCys: 0.267 ± 0.015	1.284HisAsp: 1.284 ± 0.035	1.19HisGlu: 1.19 ± 0.03	0.857HisPhe: 0.857 ± 0.026	2.117HisGly: 2.117 ± 0.041	0.642HisHis: 0.642 ± 0.023	0.791HisIle: 0.791 ± 0.023	0.507HisLys: 0.507 ± 0.021	2.231HisLeu: 2.231 ± 0.044	0.388HisMet: 0.388 ± 0.017	0.453HisAsn: 0.453 ± 0.019	1.506HisPro: 1.506 ± 0.036	0.578HisGln: 0.578 ± 0.023	1.763HisArg: 1.763 ± 0.044	0.911HisSer: 0.911 ± 0.023	0.871HisThr: 0.871 ± 0.025	1.532HisVal: 1.532 ± 0.037	0.434HisTrp: 0.434 ± 0.017	0.68HisTyr: 0.68 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.186IleAla: 6.186 ± 0.08	0.435IleCys: 0.435 ± 0.018	3.418IleAsp: 3.418 ± 0.052	3.397IleGlu: 3.397 ± 0.047	1.2IlePhe: 1.2 ± 0.032	4.358IleGly: 4.358 ± 0.062	0.903IleHis: 0.903 ± 0.025	1.285IleIle: 1.285 ± 0.036	1.19IleLys: 1.19 ± 0.035	3.211IleLeu: 3.211 ± 0.054	0.659IleMet: 0.659 ± 0.025	1.2IleAsn: 1.2 ± 0.031	2.061IlePro: 2.061 ± 0.047	1.11IleGln: 1.11 ± 0.028	3.101IleArg: 3.101 ± 0.052	2.022IleSer: 2.022 ± 0.041	2.103IleThr: 2.103 ± 0.043	3.711IleVal: 3.711 ± 0.052	0.538IleTrp: 0.538 ± 0.02	0.949IleTyr: 0.949 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	3.273LysAla: 3.273 ± 0.06	0.162LysCys: 0.162 ± 0.011	1.353LysAsp: 1.353 ± 0.037	1.008LysGlu: 1.008 ± 0.036	0.676LysPhe: 0.676 ± 0.026	1.773LysGly: 1.773 ± 0.042	0.533LysHis: 0.533 ± 0.023	1.193LysIle: 1.193 ± 0.035	0.955LysLys: 0.955 ± 0.041	2.898LysLeu: 2.898 ± 0.053	0.555LysMet: 0.555 ± 0.021	0.662LysAsn: 0.662 ± 0.028	1.672LysPro: 1.672 ± 0.041	0.98LysGln: 0.98 ± 0.029	1.951LysArg: 1.951 ± 0.045	1.209LysSer: 1.209 ± 0.032	1.523LysThr: 1.523 ± 0.037	1.837LysVal: 1.837 ± 0.044	0.3LysTrp: 0.3 ± 0.017	0.54LysTyr: 0.54 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.028LeuAla: 14.028 ± 0.137	1.102LeuCys: 1.102 ± 0.029	6.854LeuAsp: 6.854 ± 0.077	5.464LeuGlu: 5.464 ± 0.072	3.544LeuPhe: 3.544 ± 0.061	8.792LeuGly: 8.792 ± 0.087	2.358LeuHis: 2.358 ± 0.048	4.459LeuIle: 4.459 ± 0.069	2.942LeuLys: 2.942 ± 0.061	11.671LeuLeu: 11.671 ± 0.137	2.202LeuMet: 2.202 ± 0.042	2.368LeuAsn: 2.368 ± 0.047	6.233LeuPro: 6.233 ± 0.083	3.976LeuGln: 3.976 ± 0.063	9.561LeuArg: 9.561 ± 0.123	5.868LeuSer: 5.868 ± 0.071	5.059LeuThr: 5.059 ± 0.052	7.394LeuVal: 7.394 ± 0.076	1.412LeuTrp: 1.412 ± 0.036	2.298LeuTyr: 2.298 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	2.442MetAla: 2.442 ± 0.045	0.165MetCys: 0.165 ± 0.013	0.986MetAsp: 0.986 ± 0.024	0.888MetGlu: 0.888 ± 0.031	0.644MetPhe: 0.644 ± 0.021	1.458MetGly: 1.458 ± 0.035	0.474MetHis: 0.474 ± 0.018	0.971MetIle: 0.971 ± 0.03	0.796MetLys: 0.796 ± 0.026	2.449MetLeu: 2.449 ± 0.045	0.464MetMet: 0.464 ± 0.018	0.719MetAsn: 0.719 ± 0.024	1.355MetPro: 1.355 ± 0.03	0.88MetGln: 0.88 ± 0.026	1.874MetArg: 1.874 ± 0.043	1.563MetSer: 1.563 ± 0.033	1.413MetThr: 1.413 ± 0.029	1.293MetVal: 1.293 ± 0.029	0.182MetTrp: 0.182 ± 0.011	0.368MetTyr: 0.368 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.901AsnAla: 2.901 ± 0.047	0.249AsnCys: 0.249 ± 0.013	1.305AsnAsp: 1.305 ± 0.036	1.137AsnGlu: 1.137 ± 0.03	0.86AsnPhe: 0.86 ± 0.029	2.083AsnGly: 2.083 ± 0.049	0.479AsnHis: 0.479 ± 0.02	1.068AsnIle: 1.068 ± 0.031	0.549AsnLys: 0.549 ± 0.018	2.564AsnLeu: 2.564 ± 0.046	0.427AsnMet: 0.427 ± 0.018	0.641AsnAsn: 0.641 ± 0.027	1.74AsnPro: 1.74 ± 0.04	0.731AsnGln: 0.731 ± 0.024	1.75AsnArg: 1.75 ± 0.038	0.937AsnSer: 0.937 ± 0.03	1.165AsnThr: 1.165 ± 0.031	1.774AsnVal: 1.774 ± 0.037	0.395AsnTrp: 0.395 ± 0.018	0.63AsnTyr: 0.63 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.29ProAla: 7.29 ± 0.099	0.362ProCys: 0.362 ± 0.017	3.777ProAsp: 3.777 ± 0.056	3.537ProGlu: 3.537 ± 0.05	1.727ProPhe: 1.727 ± 0.037	4.822ProGly: 4.822 ± 0.062	1.077ProHis: 1.077 ± 0.028	1.82ProIle: 1.82 ± 0.033	1.228ProLys: 1.228 ± 0.033	5.602ProLeu: 5.602 ± 0.079	1.266ProMet: 1.266 ± 0.033	1.173ProAsn: 1.173 ± 0.041	3.227ProPro: 3.227 ± 0.069	2.334ProGln: 2.334 ± 0.04	3.626ProArg: 3.626 ± 0.054	2.586ProSer: 2.586 ± 0.045	2.754ProThr: 2.754 ± 0.081	4.285ProVal: 4.285 ± 0.063	0.749ProTrp: 0.749 ± 0.024	1.248ProTyr: 1.248 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.953GlnAla: 4.953 ± 0.073	0.291GlnCys: 0.291 ± 0.014	1.583GlnAsp: 1.583 ± 0.031	1.327GlnGlu: 1.327 ± 0.039	1.23GlnPhe: 1.23 ± 0.033	2.528GlnGly: 2.528 ± 0.044	0.834GlnHis: 0.834 ± 0.025	1.79GlnIle: 1.79 ± 0.034	0.92GlnLys: 0.92 ± 0.028	3.944GlnLeu: 3.944 ± 0.059	0.883GlnMet: 0.883 ± 0.026	0.736GlnAsn: 0.736 ± 0.027	2.118GlnPro: 2.118 ± 0.04	1.723GlnGln: 1.723 ± 0.046	3.537GlnArg: 3.537 ± 0.05	1.74GlnSer: 1.74 ± 0.034	1.952GlnThr: 1.952 ± 0.038	2.562GlnVal: 2.562 ± 0.043	0.594GlnTrp: 0.594 ± 0.02	0.809GlnTyr: 0.809 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	9.009ArgAla: 9.009 ± 0.104	0.726ArgCys: 0.726 ± 0.024	4.626ArgAsp: 4.626 ± 0.057	5.159ArgGlu: 5.159 ± 0.066	3.171ArgPhe: 3.171 ± 0.052	5.474ArgGly: 5.474 ± 0.063	2.06ArgHis: 2.06 ± 0.044	4.201ArgIle: 4.201 ± 0.064	1.993ArgLys: 1.993 ± 0.044	9.452ArgLeu: 9.452 ± 0.097	1.919ArgMet: 1.919 ± 0.031	1.845ArgAsn: 1.845 ± 0.038	3.763ArgPro: 3.763 ± 0.061	2.905ArgGln: 2.905 ± 0.056	7.135ArgArg: 7.135 ± 0.094	4.009ArgSer: 4.009 ± 0.06	3.647ArgThr: 3.647 ± 0.054	5.867ArgVal: 5.867 ± 0.062	1.424ArgTrp: 1.424 ± 0.034	2.519ArgTyr: 2.519 ± 0.053	0.0ArgXaa: 0.0 ± 0.0
Ser	6.181SerAla: 6.181 ± 0.078	0.469SerCys: 0.469 ± 0.018	2.707SerAsp: 2.707 ± 0.049	2.529SerGlu: 2.529 ± 0.052	1.931SerPhe: 1.931 ± 0.039	5.33SerGly: 5.33 ± 0.078	0.929SerHis: 0.929 ± 0.028	2.14SerIle: 2.14 ± 0.043	1.176SerLys: 1.176 ± 0.03	5.195SerLeu: 5.195 ± 0.063	1.105SerMet: 1.105 ± 0.031	1.206SerAsn: 1.206 ± 0.034	2.795SerPro: 2.795 ± 0.048	1.543SerGln: 1.543 ± 0.033	3.683SerArg: 3.683 ± 0.056	2.55SerSer: 2.55 ± 0.054	2.535SerThr: 2.535 ± 0.046	3.832SerVal: 3.832 ± 0.056	0.717SerTrp: 0.717 ± 0.023	1.223SerTyr: 1.223 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.076ThrAla: 6.076 ± 0.069	0.418ThrCys: 0.418 ± 0.02	2.692ThrAsp: 2.692 ± 0.051	2.405ThrGlu: 2.405 ± 0.037	1.48ThrPhe: 1.48 ± 0.037	4.618ThrGly: 4.618 ± 0.065	1.069ThrHis: 1.069 ± 0.026	2.067ThrIle: 2.067 ± 0.038	0.956ThrLys: 0.956 ± 0.032	6.25ThrLeu: 6.25 ± 0.063	1.003ThrMet: 1.003 ± 0.031	1.009ThrAsn: 1.009 ± 0.029	3.745ThrPro: 3.745 ± 0.087	1.743ThrGln: 1.743 ± 0.037	3.742ThrArg: 3.742 ± 0.06	2.222ThrSer: 2.222 ± 0.047	2.581ThrThr: 2.581 ± 0.055	4.055ThrVal: 4.055 ± 0.063	0.695ThrTrp: 0.695 ± 0.021	1.074ThrTyr: 1.074 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	8.955ValAla: 8.955 ± 0.097	0.777ValCys: 0.777 ± 0.025	4.876ValAsp: 4.876 ± 0.06	4.566ValGlu: 4.566 ± 0.066	2.635ValPhe: 2.635 ± 0.048	5.627ValGly: 5.627 ± 0.07	1.622ValHis: 1.622 ± 0.038	3.35ValIle: 3.35 ± 0.054	1.726ValLys: 1.726 ± 0.047	8.088ValLeu: 8.088 ± 0.083	1.57ValMet: 1.57 ± 0.037	1.946ValAsn: 1.946 ± 0.044	4.108ValPro: 4.108 ± 0.058	2.422ValGln: 2.422 ± 0.046	5.611ValArg: 5.611 ± 0.064	3.932ValSer: 3.932 ± 0.046	3.929ValThr: 3.929 ± 0.074	6.085ValVal: 6.085 ± 0.076	0.934ValTrp: 0.934 ± 0.029	1.612ValTyr: 1.612 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.348TrpAla: 1.348 ± 0.035	0.176TrpCys: 0.176 ± 0.011	0.703TrpAsp: 0.703 ± 0.025	0.573TrpGlu: 0.573 ± 0.02	0.578TrpPhe: 0.578 ± 0.021	0.942TrpGly: 0.942 ± 0.026	0.38TrpHis: 0.38 ± 0.018	0.739TrpIle: 0.739 ± 0.024	0.366TrpLys: 0.366 ± 0.016	2.092TrpLeu: 2.092 ± 0.042	0.378TrpMet: 0.378 ± 0.015	0.435TrpAsn: 0.435 ± 0.018	0.765TrpPro: 0.765 ± 0.025	0.728TrpGln: 0.728 ± 0.023	1.355TrpArg: 1.355 ± 0.037	0.813TrpSer: 0.813 ± 0.027	0.886TrpThr: 0.886 ± 0.028	0.949TrpVal: 0.949 ± 0.024	0.292TrpTrp: 0.292 ± 0.018	0.339TrpTyr: 0.339 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.941TyrAla: 2.941 ± 0.049	0.257TyrCys: 0.257 ± 0.014	1.492TyrAsp: 1.492 ± 0.036	1.388TyrGlu: 1.388 ± 0.033	0.966TyrPhe: 0.966 ± 0.027	2.193TyrGly: 2.193 ± 0.046	0.472TyrHis: 0.472 ± 0.018	0.816TyrIle: 0.816 ± 0.023	0.527TyrLys: 0.527 ± 0.023	2.494TyrLeu: 2.494 ± 0.047	0.395TyrMet: 0.395 ± 0.019	0.652TyrAsn: 0.652 ± 0.025	1.191TyrPro: 1.191 ± 0.029	0.758TyrGln: 0.758 ± 0.025	2.294TyrArg: 2.294 ± 0.043	1.219TyrSer: 1.219 ± 0.031	1.219TyrThr: 1.219 ± 0.033	1.82TyrVal: 1.82 ± 0.035	0.38TyrTrp: 0.38 ± 0.018	0.716TyrTyr: 0.716 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4018 proteins (1348336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---