Amino acid dipepetide frequency for Tamilnaduibacter salinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.384AlaAla: 9.384 ± 0.12	0.968AlaCys: 0.968 ± 0.032	6.018AlaAsp: 6.018 ± 0.083	6.181AlaGlu: 6.181 ± 0.095	3.596AlaPhe: 3.596 ± 0.062	8.328AlaGly: 8.328 ± 0.098	1.973AlaHis: 1.973 ± 0.043	5.213AlaIle: 5.213 ± 0.078	2.42AlaLys: 2.42 ± 0.066	11.564AlaLeu: 11.564 ± 0.134	2.981AlaMet: 2.981 ± 0.057	2.67AlaAsn: 2.67 ± 0.056	4.225AlaPro: 4.225 ± 0.067	3.301AlaGln: 3.301 ± 0.055	7.197AlaArg: 7.197 ± 0.102	5.949AlaSer: 5.949 ± 0.079	4.942AlaThr: 4.942 ± 0.075	7.009AlaVal: 7.009 ± 0.083	1.378AlaTrp: 1.378 ± 0.039	2.208AlaTyr: 2.208 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.759CysAla: 0.759 ± 0.027	0.129CysCys: 0.129 ± 0.011	0.584CysAsp: 0.584 ± 0.025	0.566CysGlu: 0.566 ± 0.024	0.346CysPhe: 0.346 ± 0.018	0.855CysGly: 0.855 ± 0.031	0.313CysHis: 0.313 ± 0.017	0.375CysIle: 0.375 ± 0.018	0.188CysLys: 0.188 ± 0.015	0.968CysLeu: 0.968 ± 0.028	0.164CysMet: 0.164 ± 0.015	0.201CysAsn: 0.201 ± 0.014	0.496CysPro: 0.496 ± 0.026	0.399CysGln: 0.399 ± 0.019	0.742CysArg: 0.742 ± 0.03	0.477CysSer: 0.477 ± 0.023	0.384CysThr: 0.384 ± 0.022	0.608CysVal: 0.608 ± 0.027	0.117CysTrp: 0.117 ± 0.01	0.23CysTyr: 0.23 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	6.038AspAla: 6.038 ± 0.086	0.498AspCys: 0.498 ± 0.025	4.493AspAsp: 4.493 ± 0.087	4.501AspGlu: 4.501 ± 0.076	2.209AspPhe: 2.209 ± 0.05	5.193AspGly: 5.193 ± 0.096	1.567AspHis: 1.567 ± 0.04	3.052AspIle: 3.052 ± 0.064	1.57AspLys: 1.57 ± 0.049	6.148AspLeu: 6.148 ± 0.09	1.456AspMet: 1.456 ± 0.041	1.912AspAsn: 1.912 ± 0.044	3.253AspPro: 3.253 ± 0.061	2.998AspGln: 2.998 ± 0.056	5.063AspArg: 5.063 ± 0.073	3.232AspSer: 3.232 ± 0.065	3.25AspThr: 3.25 ± 0.059	4.57AspVal: 4.57 ± 0.075	1.154AspTrp: 1.154 ± 0.04	1.87AspTyr: 1.87 ± 0.049	0.0AspXaa: 0.0 ± 0.0
Glu	7.159GluAla: 7.159 ± 0.085	0.462GluCys: 0.462 ± 0.024	3.543GluAsp: 3.543 ± 0.07	4.08GluGlu: 4.08 ± 0.087	1.844GluPhe: 1.844 ± 0.044	4.479GluGly: 4.479 ± 0.069	1.53GluHis: 1.53 ± 0.044	2.824GluIle: 2.824 ± 0.055	2.672GluLys: 2.672 ± 0.062	6.433GluLeu: 6.433 ± 0.091	1.564GluMet: 1.564 ± 0.037	2.018GluAsn: 2.018 ± 0.044	3.226GluPro: 3.226 ± 0.075	3.47GluGln: 3.47 ± 0.064	5.584GluArg: 5.584 ± 0.092	3.951GluSer: 3.951 ± 0.069	3.893GluThr: 3.893 ± 0.064	4.138GluVal: 4.138 ± 0.063	0.822GluTrp: 0.822 ± 0.03	1.41GluTyr: 1.41 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	3.159PheAla: 3.159 ± 0.053	0.38PheCys: 0.38 ± 0.022	2.532PheAsp: 2.532 ± 0.049	2.328PheGlu: 2.328 ± 0.048	1.454PhePhe: 1.454 ± 0.044	3.032PheGly: 3.032 ± 0.061	0.829PheHis: 0.829 ± 0.029	1.614PheIle: 1.614 ± 0.044	0.914PheLys: 0.914 ± 0.03	3.498PheLeu: 3.498 ± 0.059	0.84PheMet: 0.84 ± 0.028	1.25PheAsn: 1.25 ± 0.038	1.593PhePro: 1.593 ± 0.048	1.389PheGln: 1.389 ± 0.042	2.696PheArg: 2.696 ± 0.055	2.462PheSer: 2.462 ± 0.044	1.823PheThr: 1.823 ± 0.047	2.396PheVal: 2.396 ± 0.05	0.559PheTrp: 0.559 ± 0.022	1.048PheTyr: 1.048 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	6.795GlyAla: 6.795 ± 0.107	0.91GlyCys: 0.91 ± 0.036	5.051GlyAsp: 5.051 ± 0.09	5.291GlyGlu: 5.291 ± 0.077	3.298GlyPhe: 3.298 ± 0.07	6.209GlyGly: 6.209 ± 0.103	2.051GlyHis: 2.051 ± 0.045	4.269GlyIle: 4.269 ± 0.078	2.631GlyLys: 2.631 ± 0.065	8.302GlyLeu: 8.302 ± 0.11	2.305GlyMet: 2.305 ± 0.045	2.347GlyAsn: 2.347 ± 0.054	2.86GlyPro: 2.86 ± 0.055	3.565GlyGln: 3.565 ± 0.065	5.287GlyArg: 5.287 ± 0.08	4.375GlySer: 4.375 ± 0.07	4.164GlyThr: 4.164 ± 0.073	5.853GlyVal: 5.853 ± 0.089	1.302GlyTrp: 1.302 ± 0.042	2.407GlyTyr: 2.407 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.955HisAla: 1.955 ± 0.051	0.346HisCys: 0.346 ± 0.019	1.34HisAsp: 1.34 ± 0.037	1.312HisGlu: 1.312 ± 0.036	0.993HisPhe: 0.993 ± 0.034	1.905HisGly: 1.905 ± 0.044	0.823HisHis: 0.823 ± 0.032	1.028HisIle: 1.028 ± 0.032	0.553HisLys: 0.553 ± 0.024	2.44HisLeu: 2.44 ± 0.053	0.478HisMet: 0.478 ± 0.023	0.616HisAsn: 0.616 ± 0.025	1.587HisPro: 1.587 ± 0.045	1.102HisGln: 1.102 ± 0.031	1.948HisArg: 1.948 ± 0.046	1.259HisSer: 1.259 ± 0.032	1.052HisThr: 1.052 ± 0.032	1.395HisVal: 1.395 ± 0.036	0.467HisTrp: 0.467 ± 0.02	0.838HisTyr: 0.838 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	4.974IleAla: 4.974 ± 0.086	0.422IleCys: 0.422 ± 0.024	3.538IleAsp: 3.538 ± 0.063	3.442IleGlu: 3.442 ± 0.065	1.326IlePhe: 1.326 ± 0.043	4.253IleGly: 4.253 ± 0.086	1.212IleHis: 1.212 ± 0.036	2.147IleIle: 2.147 ± 0.056	1.391IleLys: 1.391 ± 0.046	4.228IleLeu: 4.228 ± 0.078	1.015IleMet: 1.015 ± 0.027	1.771IleAsn: 1.771 ± 0.044	2.393IlePro: 2.393 ± 0.051	1.899IleGln: 1.899 ± 0.044	3.915IleArg: 3.915 ± 0.056	2.707IleSer: 2.707 ± 0.055	2.68IleThr: 2.68 ± 0.053	3.337IleVal: 3.337 ± 0.057	0.545IleTrp: 0.545 ± 0.027	1.096IleTyr: 1.096 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	3.283LysAla: 3.283 ± 0.074	0.147LysCys: 0.147 ± 0.012	1.7LysAsp: 1.7 ± 0.047	1.764LysGlu: 1.764 ± 0.055	0.599LysPhe: 0.599 ± 0.024	2.309LysGly: 2.309 ± 0.05	0.645LysHis: 0.645 ± 0.028	1.211LysIle: 1.211 ± 0.041	1.348LysLys: 1.348 ± 0.053	2.822LysLeu: 2.822 ± 0.055	0.666LysMet: 0.666 ± 0.025	0.875LysAsn: 0.875 ± 0.03	1.682LysPro: 1.682 ± 0.044	1.393LysGln: 1.393 ± 0.048	2.303LysArg: 2.303 ± 0.058	1.673LysSer: 1.673 ± 0.05	1.865LysThr: 1.865 ± 0.043	2.035LysVal: 2.035 ± 0.055	0.297LysTrp: 0.297 ± 0.021	0.597LysTyr: 0.597 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	11.267LeuAla: 11.267 ± 0.119	1.004LeuCys: 1.004 ± 0.036	6.705LeuAsp: 6.705 ± 0.088	6.658LeuGlu: 6.658 ± 0.092	3.708LeuPhe: 3.708 ± 0.064	7.814LeuGly: 7.814 ± 0.105	2.09LeuHis: 2.09 ± 0.049	5.224LeuIle: 5.224 ± 0.082	3.515LeuLys: 3.515 ± 0.062	10.239LeuLeu: 10.239 ± 0.138	2.758LeuMet: 2.758 ± 0.054	3.445LeuAsn: 3.445 ± 0.062	5.272LeuPro: 5.272 ± 0.081	3.537LeuGln: 3.537 ± 0.061	7.077LeuArg: 7.077 ± 0.102	7.375LeuSer: 7.375 ± 0.095	6.267LeuThr: 6.267 ± 0.081	7.465LeuVal: 7.465 ± 0.102	1.272LeuTrp: 1.272 ± 0.044	2.349LeuTyr: 2.349 ± 0.048	0.0LeuXaa: 0.0 ± 0.0
Met	3.131MetAla: 3.131 ± 0.057	0.173MetCys: 0.173 ± 0.012	1.443MetAsp: 1.443 ± 0.038	1.419MetGlu: 1.419 ± 0.039	0.598MetPhe: 0.598 ± 0.024	1.946MetGly: 1.946 ± 0.05	0.477MetHis: 0.477 ± 0.023	1.192MetIle: 1.192 ± 0.036	0.97MetLys: 0.97 ± 0.032	2.512MetLeu: 2.512 ± 0.053	0.713MetMet: 0.713 ± 0.032	0.832MetAsn: 0.832 ± 0.028	1.432MetPro: 1.432 ± 0.041	0.889MetGln: 0.889 ± 0.032	1.497MetArg: 1.497 ± 0.033	1.66MetSer: 1.66 ± 0.04	1.863MetThr: 1.863 ± 0.043	1.752MetVal: 1.752 ± 0.042	0.15MetTrp: 0.15 ± 0.013	0.35MetTyr: 0.35 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.149AsnAla: 3.149 ± 0.058	0.242AsnCys: 0.242 ± 0.016	1.819AsnAsp: 1.819 ± 0.044	1.805AsnGlu: 1.805 ± 0.047	0.875AsnPhe: 0.875 ± 0.029	2.629AsnGly: 2.629 ± 0.058	0.744AsnHis: 0.744 ± 0.026	1.336AsnIle: 1.336 ± 0.042	0.777AsnLys: 0.777 ± 0.029	3.074AsnLeu: 3.074 ± 0.057	0.642AsnMet: 0.642 ± 0.026	0.969AsnAsn: 0.969 ± 0.035	1.891AsnPro: 1.891 ± 0.044	1.329AsnGln: 1.329 ± 0.035	2.451AsnArg: 2.451 ± 0.054	1.334AsnSer: 1.334 ± 0.036	1.639AsnThr: 1.639 ± 0.042	2.052AsnVal: 2.052 ± 0.047	0.427AsnTrp: 0.427 ± 0.022	0.737AsnTyr: 0.737 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.683ProAla: 4.683 ± 0.078	0.347ProCys: 0.347 ± 0.019	4.267ProAsp: 4.267 ± 0.072	4.512ProGlu: 4.512 ± 0.071	1.823ProPhe: 1.823 ± 0.039	4.17ProGly: 4.17 ± 0.072	0.952ProHis: 0.952 ± 0.029	2.078ProIle: 2.078 ± 0.05	1.278ProLys: 1.278 ± 0.042	4.752ProLeu: 4.752 ± 0.082	1.221ProMet: 1.221 ± 0.03	1.294ProAsn: 1.294 ± 0.037	2.065ProPro: 2.065 ± 0.051	1.5ProGln: 1.5 ± 0.039	2.545ProArg: 2.545 ± 0.057	2.783ProSer: 2.783 ± 0.054	2.355ProThr: 2.355 ± 0.052	4.397ProVal: 4.397 ± 0.072	0.739ProTrp: 0.739 ± 0.03	1.14ProTyr: 1.14 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	4.649GlnAla: 4.649 ± 0.073	0.311GlnCys: 0.311 ± 0.019	1.948GlnAsp: 1.948 ± 0.049	2.183GlnGlu: 2.183 ± 0.054	1.397GlnPhe: 1.397 ± 0.037	3.122GlnGly: 3.122 ± 0.058	0.893GlnHis: 0.893 ± 0.034	1.731GlnIle: 1.731 ± 0.045	1.315GlnLys: 1.315 ± 0.046	4.103GlnLeu: 4.103 ± 0.07	1.02GlnMet: 1.02 ± 0.032	1.126GlnAsn: 1.126 ± 0.039	2.164GlnPro: 2.164 ± 0.048	2.151GlnGln: 2.151 ± 0.06	3.35GlnArg: 3.35 ± 0.073	2.86GlnSer: 2.86 ± 0.055	2.244GlnThr: 2.244 ± 0.048	2.967GlnVal: 2.967 ± 0.06	0.75GlnTrp: 0.75 ± 0.029	1.021GlnTyr: 1.021 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	6.113ArgAla: 6.113 ± 0.089	0.617ArgCys: 0.617 ± 0.025	4.584ArgAsp: 4.584 ± 0.08	5.262ArgGlu: 5.262 ± 0.088	3.309ArgPhe: 3.309 ± 0.055	4.247ArgGly: 4.247 ± 0.063	2.137ArgHis: 2.137 ± 0.05	3.961ArgIle: 3.961 ± 0.073	2.299ArgLys: 2.299 ± 0.055	8.8ArgLeu: 8.8 ± 0.116	1.799ArgMet: 1.799 ± 0.039	2.155ArgAsn: 2.155 ± 0.05	3.249ArgPro: 3.249 ± 0.066	3.893ArgGln: 3.893 ± 0.07	5.923ArgArg: 5.923 ± 0.1	3.903ArgSer: 3.903 ± 0.073	3.225ArgThr: 3.225 ± 0.057	5.134ArgVal: 5.134 ± 0.087	1.195ArgTrp: 1.195 ± 0.037	2.276ArgTyr: 2.276 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.655SerAla: 5.655 ± 0.067	0.403SerCys: 0.403 ± 0.022	4.048SerAsp: 4.048 ± 0.08	3.869SerGlu: 3.869 ± 0.069	2.093SerPhe: 2.093 ± 0.044	5.759SerGly: 5.759 ± 0.088	1.414SerHis: 1.414 ± 0.04	2.694SerIle: 2.694 ± 0.057	1.439SerLys: 1.439 ± 0.045	6.544SerLeu: 6.544 ± 0.102	1.46SerMet: 1.46 ± 0.035	1.61SerAsn: 1.61 ± 0.04	2.823SerPro: 2.823 ± 0.058	2.323SerGln: 2.323 ± 0.051	4.264SerArg: 4.264 ± 0.064	3.318SerSer: 3.318 ± 0.068	2.774SerThr: 2.774 ± 0.061	4.606SerVal: 4.606 ± 0.071	0.77SerTrp: 0.77 ± 0.032	1.25SerTyr: 1.25 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.129ThrAla: 5.129 ± 0.079	0.464ThrCys: 0.464 ± 0.02	3.46ThrAsp: 3.46 ± 0.052	3.105ThrGlu: 3.105 ± 0.06	1.867ThrPhe: 1.867 ± 0.047	5.026ThrGly: 5.026 ± 0.079	1.163ThrHis: 1.163 ± 0.031	2.739ThrIle: 2.739 ± 0.049	1.05ThrLys: 1.05 ± 0.035	6.65ThrLeu: 6.65 ± 0.096	1.193ThrMet: 1.193 ± 0.033	1.422ThrAsn: 1.422 ± 0.041	3.216ThrPro: 3.216 ± 0.056	1.737ThrGln: 1.737 ± 0.039	3.6ThrArg: 3.6 ± 0.059	2.788ThrSer: 2.788 ± 0.06	2.934ThrThr: 2.934 ± 0.061	4.382ThrVal: 4.382 ± 0.074	0.698ThrTrp: 0.698 ± 0.027	1.185ThrTyr: 1.185 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	7.195ValAla: 7.195 ± 0.1	0.654ValCys: 0.654 ± 0.027	4.665ValAsp: 4.665 ± 0.074	4.554ValGlu: 4.554 ± 0.068	2.762ValPhe: 2.762 ± 0.057	5.119ValGly: 5.119 ± 0.074	1.52ValHis: 1.52 ± 0.037	3.948ValIle: 3.948 ± 0.077	1.903ValLys: 1.903 ± 0.054	7.302ValLeu: 7.302 ± 0.098	1.869ValMet: 1.869 ± 0.048	2.286ValAsn: 2.286 ± 0.048	3.46ValPro: 3.46 ± 0.065	2.307ValGln: 2.307 ± 0.047	5.139ValArg: 5.139 ± 0.071	4.819ValSer: 4.819 ± 0.074	4.585ValThr: 4.585 ± 0.069	5.921ValVal: 5.921 ± 0.089	0.838ValTrp: 0.838 ± 0.028	1.607ValTyr: 1.607 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.994TrpAla: 0.994 ± 0.034	0.165TrpCys: 0.165 ± 0.013	0.71TrpAsp: 0.71 ± 0.028	0.73TrpGlu: 0.73 ± 0.031	0.647TrpPhe: 0.647 ± 0.025	0.859TrpGly: 0.859 ± 0.027	0.432TrpHis: 0.432 ± 0.022	0.635TrpIle: 0.635 ± 0.027	0.364TrpLys: 0.364 ± 0.019	2.047TrpLeu: 2.047 ± 0.054	0.38TrpMet: 0.38 ± 0.025	0.401TrpAsn: 0.401 ± 0.023	0.709TrpPro: 0.709 ± 0.029	0.835TrpGln: 0.835 ± 0.03	1.144TrpArg: 1.144 ± 0.034	0.85TrpSer: 0.85 ± 0.03	0.639TrpThr: 0.639 ± 0.028	0.964TrpVal: 0.964 ± 0.032	0.23TrpTrp: 0.23 ± 0.014	0.357TrpTyr: 0.357 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.033TyrAla: 2.033 ± 0.042	0.261TyrCys: 0.261 ± 0.015	1.579TyrAsp: 1.579 ± 0.044	1.541TyrGlu: 1.541 ± 0.042	1.053TyrPhe: 1.053 ± 0.035	2.017TyrGly: 2.017 ± 0.044	0.671TyrHis: 0.671 ± 0.028	1.021TyrIle: 1.021 ± 0.033	0.618TyrLys: 0.618 ± 0.027	2.617TyrLeu: 2.617 ± 0.053	0.473TyrMet: 0.473 ± 0.022	0.722TyrAsn: 0.722 ± 0.029	1.301TyrPro: 1.301 ± 0.042	1.289TyrGln: 1.289 ± 0.039	2.357TyrArg: 2.357 ± 0.054	1.341TyrSer: 1.341 ± 0.041	1.228TyrThr: 1.228 ± 0.039	1.471TyrVal: 1.471 ± 0.038	0.383TyrTrp: 0.383 ± 0.019	0.766TyrTyr: 0.766 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3136 proteins (1009489 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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