Amino acid dipepetide frequency for Podoviridae sp. cty5g4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.007AlaAla: 5.007 ± 0.671
0.794AlaCys: 0.794 ± 0.255
3.602AlaAsp: 3.602 ± 0.569
4.03AlaGlu: 4.03 ± 0.546
2.381AlaPhe: 2.381 ± 0.358
7.327AlaGly: 7.327 ± 0.868
0.855AlaHis: 0.855 ± 0.213
6.594AlaIle: 6.594 ± 0.486
5.739AlaLys: 5.739 ± 0.64
6.228AlaLeu: 6.228 ± 0.556
1.649AlaMet: 1.649 ± 0.294
2.442AlaAsn: 2.442 ± 0.658
2.442AlaPro: 2.442 ± 0.416
2.137AlaGln: 2.137 ± 0.373
2.625AlaArg: 2.625 ± 0.441
5.556AlaSer: 5.556 ± 0.67
5.129AlaThr: 5.129 ± 0.653
4.396AlaVal: 4.396 ± 0.683
0.611AlaTrp: 0.611 ± 0.198
2.137AlaTyr: 2.137 ± 0.487
0.0AlaXaa: 0.0 ± 0.0
Cys
0.305CysAla: 0.305 ± 0.153
0.427CysCys: 0.427 ± 0.171
0.977CysAsp: 0.977 ± 0.317
0.916CysGlu: 0.916 ± 0.329
0.244CysPhe: 0.244 ± 0.109
1.16CysGly: 1.16 ± 0.319
0.305CysHis: 0.305 ± 0.171
0.794CysIle: 0.794 ± 0.241
1.282CysLys: 1.282 ± 0.337
1.038CysLeu: 1.038 ± 0.316
0.244CysMet: 0.244 ± 0.166
0.55CysAsn: 0.55 ± 0.186
1.099CysPro: 1.099 ± 0.313
0.122CysGln: 0.122 ± 0.094
0.611CysArg: 0.611 ± 0.195
0.733CysSer: 0.733 ± 0.266
0.977CysThr: 0.977 ± 0.294
0.916CysVal: 0.916 ± 0.269
0.183CysTrp: 0.183 ± 0.109
0.488CysTyr: 0.488 ± 0.196
0.0CysXaa: 0.0 ± 0.0
Asp
4.03AspAla: 4.03 ± 0.419
0.733AspCys: 0.733 ± 0.252
2.809AspAsp: 2.809 ± 0.387
3.358AspGlu: 3.358 ± 0.443
2.259AspPhe: 2.259 ± 0.348
3.786AspGly: 3.786 ± 0.847
0.55AspHis: 0.55 ± 0.147
5.556AspIle: 5.556 ± 0.642
4.701AspLys: 4.701 ± 0.818
3.297AspLeu: 3.297 ± 0.45
1.221AspMet: 1.221 ± 0.309
2.381AspAsn: 2.381 ± 0.496
1.649AspPro: 1.649 ± 0.339
0.977AspGln: 0.977 ± 0.289
1.771AspArg: 1.771 ± 0.335
2.381AspSer: 2.381 ± 0.502
3.175AspThr: 3.175 ± 0.505
3.236AspVal: 3.236 ± 0.426
0.977AspTrp: 0.977 ± 0.295
2.259AspTyr: 2.259 ± 0.415
0.0AspXaa: 0.0 ± 0.0
Glu
4.213GluAla: 4.213 ± 0.559
0.916GluCys: 0.916 ± 0.297
3.908GluAsp: 3.908 ± 0.604
4.762GluGlu: 4.762 ± 0.699
2.015GluPhe: 2.015 ± 0.388
4.213GluGly: 4.213 ± 0.502
0.977GluHis: 0.977 ± 0.292
6.533GluIle: 6.533 ± 0.786
4.518GluLys: 4.518 ± 0.554
5.251GluLeu: 5.251 ± 0.735
1.771GluMet: 1.771 ± 0.353
3.786GluAsn: 3.786 ± 0.556
1.954GluPro: 1.954 ± 0.535
2.809GluGln: 2.809 ± 0.535
3.358GluArg: 3.358 ± 0.547
3.786GluSer: 3.786 ± 0.533
4.152GluThr: 4.152 ± 0.629
3.358GluVal: 3.358 ± 0.52
1.343GluTrp: 1.343 ± 0.252
2.992GluTyr: 2.992 ± 0.476
0.0GluXaa: 0.0 ± 0.0
Phe
2.503PheAla: 2.503 ± 0.418
0.366PheCys: 0.366 ± 0.176
1.893PheAsp: 1.893 ± 0.296
2.259PheGlu: 2.259 ± 0.351
1.16PhePhe: 1.16 ± 0.279
2.198PheGly: 2.198 ± 0.356
0.794PheHis: 0.794 ± 0.287
2.87PheIle: 2.87 ± 0.381
2.137PheLys: 2.137 ± 0.422
2.687PheLeu: 2.687 ± 0.446
0.916PheMet: 0.916 ± 0.299
1.465PheAsn: 1.465 ± 0.237
1.893PhePro: 1.893 ± 0.268
0.855PheGln: 0.855 ± 0.23
2.381PheArg: 2.381 ± 0.353
2.564PheSer: 2.564 ± 0.402
2.503PheThr: 2.503 ± 0.43
2.32PheVal: 2.32 ± 0.612
0.183PheTrp: 0.183 ± 0.109
1.587PheTyr: 1.587 ± 0.341
0.0PheXaa: 0.0 ± 0.0
Gly
5.129GlyAla: 5.129 ± 0.777
0.916GlyCys: 0.916 ± 0.257
3.541GlyAsp: 3.541 ± 0.501
4.152GlyGlu: 4.152 ± 0.497
2.32GlyPhe: 2.32 ± 0.413
4.824GlyGly: 4.824 ± 0.882
0.611GlyHis: 0.611 ± 0.19
6.106GlyIle: 6.106 ± 0.78
5.434GlyLys: 5.434 ± 0.544
5.617GlyLeu: 5.617 ± 0.554
2.625GlyMet: 2.625 ± 0.497
4.64GlyAsn: 4.64 ± 0.675
0.488GlyPro: 0.488 ± 0.209
2.198GlyGln: 2.198 ± 0.465
4.213GlyArg: 4.213 ± 0.444
4.701GlySer: 4.701 ± 0.656
4.152GlyThr: 4.152 ± 0.915
5.434GlyVal: 5.434 ± 0.622
1.221GlyTrp: 1.221 ± 0.283
4.152GlyTyr: 4.152 ± 0.722
0.0GlyXaa: 0.0 ± 0.0
His
0.855HisAla: 0.855 ± 0.24
0.122HisCys: 0.122 ± 0.079
0.366HisAsp: 0.366 ± 0.162
0.611HisGlu: 0.611 ± 0.181
0.794HisPhe: 0.794 ± 0.233
1.465HisGly: 1.465 ± 0.324
0.183HisHis: 0.183 ± 0.109
1.282HisIle: 1.282 ± 0.305
1.343HisLys: 1.343 ± 0.31
1.221HisLeu: 1.221 ± 0.254
0.183HisMet: 0.183 ± 0.122
0.733HisAsn: 0.733 ± 0.218
1.099HisPro: 1.099 ± 0.272
0.183HisGln: 0.183 ± 0.097
0.672HisArg: 0.672 ± 0.216
1.099HisSer: 1.099 ± 0.274
1.282HisThr: 1.282 ± 0.296
0.855HisVal: 0.855 ± 0.18
0.244HisTrp: 0.244 ± 0.119
0.855HisTyr: 0.855 ± 0.231
0.0HisXaa: 0.0 ± 0.0
Ile
5.495IleAla: 5.495 ± 0.554
1.221IleCys: 1.221 ± 0.372
4.579IleAsp: 4.579 ± 0.648
6.472IleGlu: 6.472 ± 0.821
2.32IlePhe: 2.32 ± 0.402
5.007IleGly: 5.007 ± 0.583
1.343IleHis: 1.343 ± 0.342
5.556IleIle: 5.556 ± 0.779
6.106IleLys: 6.106 ± 0.909
5.923IleLeu: 5.923 ± 0.831
1.587IleMet: 1.587 ± 0.253
3.847IleAsn: 3.847 ± 0.536
3.48IlePro: 3.48 ± 0.522
2.564IleGln: 2.564 ± 0.439
3.48IleArg: 3.48 ± 0.535
5.19IleSer: 5.19 ± 0.603
5.495IleThr: 5.495 ± 0.561
4.946IleVal: 4.946 ± 0.604
0.794IleTrp: 0.794 ± 0.218
2.809IleTyr: 2.809 ± 0.423
0.0IleXaa: 0.0 ± 0.0
Lys
5.068LysAla: 5.068 ± 0.67
0.427LysCys: 0.427 ± 0.17
4.213LysAsp: 4.213 ± 0.691
5.251LysGlu: 5.251 ± 0.829
2.809LysPhe: 2.809 ± 0.38
4.274LysGly: 4.274 ± 0.58
1.282LysHis: 1.282 ± 0.337
6.472LysIle: 6.472 ± 0.787
7.327LysLys: 7.327 ± 1.142
4.946LysLeu: 4.946 ± 0.731
2.076LysMet: 2.076 ± 0.433
5.129LysAsn: 5.129 ± 0.588
3.663LysPro: 3.663 ± 0.834
3.663LysGln: 3.663 ± 0.653
3.114LysArg: 3.114 ± 0.486
5.373LysSer: 5.373 ± 0.798
4.457LysThr: 4.457 ± 0.658
2.931LysVal: 2.931 ± 0.455
1.038LysTrp: 1.038 ± 0.231
2.87LysTyr: 2.87 ± 0.506
0.0LysXaa: 0.0 ± 0.0
Leu
5.678LeuAla: 5.678 ± 0.616
1.038LeuCys: 1.038 ± 0.245
4.213LeuAsp: 4.213 ± 0.501
5.862LeuGlu: 5.862 ± 0.772
2.625LeuPhe: 2.625 ± 0.475
4.824LeuGly: 4.824 ± 0.545
0.794LeuHis: 0.794 ± 0.219
4.518LeuIle: 4.518 ± 0.768
6.716LeuLys: 6.716 ± 0.744
6.167LeuLeu: 6.167 ± 0.587
1.71LeuMet: 1.71 ± 0.333
3.969LeuAsn: 3.969 ± 0.451
3.297LeuPro: 3.297 ± 0.615
2.992LeuGln: 2.992 ± 0.507
3.786LeuArg: 3.786 ± 0.42
5.617LeuSer: 5.617 ± 0.678
4.762LeuThr: 4.762 ± 0.615
4.03LeuVal: 4.03 ± 0.568
0.855LeuTrp: 0.855 ± 0.21
3.48LeuTyr: 3.48 ± 0.601
0.0LeuXaa: 0.0 ± 0.0
Met
2.32MetAla: 2.32 ± 0.429
0.305MetCys: 0.305 ± 0.135
1.16MetAsp: 1.16 ± 0.265
1.343MetGlu: 1.343 ± 0.316
0.977MetPhe: 0.977 ± 0.237
1.649MetGly: 1.649 ± 0.306
0.427MetHis: 0.427 ± 0.177
1.526MetIle: 1.526 ± 0.36
1.832MetLys: 1.832 ± 0.401
1.465MetLeu: 1.465 ± 0.318
0.305MetMet: 0.305 ± 0.145
1.16MetAsn: 1.16 ± 0.269
1.465MetPro: 1.465 ± 0.343
0.977MetGln: 0.977 ± 0.206
1.099MetArg: 1.099 ± 0.272
2.137MetSer: 2.137 ± 0.416
1.587MetThr: 1.587 ± 0.315
1.343MetVal: 1.343 ± 0.27
0.55MetTrp: 0.55 ± 0.2
1.038MetTyr: 1.038 ± 0.243
0.0MetXaa: 0.0 ± 0.0
Asn
4.03AsnAla: 4.03 ± 0.661
0.733AsnCys: 0.733 ± 0.225
1.71AsnAsp: 1.71 ± 0.4
3.786AsnGlu: 3.786 ± 0.452
1.526AsnPhe: 1.526 ± 0.228
3.725AsnGly: 3.725 ± 0.65
0.733AsnHis: 0.733 ± 0.217
5.007AsnIle: 5.007 ± 0.707
4.335AsnLys: 4.335 ± 0.623
3.541AsnLeu: 3.541 ± 0.555
1.404AsnMet: 1.404 ± 0.323
2.748AsnAsn: 2.748 ± 0.596
2.687AsnPro: 2.687 ± 0.407
1.587AsnGln: 1.587 ± 0.283
2.259AsnArg: 2.259 ± 0.342
2.625AsnSer: 2.625 ± 0.43
4.701AsnThr: 4.701 ± 1.207
2.687AsnVal: 2.687 ± 0.343
1.038AsnTrp: 1.038 ± 0.309
2.259AsnTyr: 2.259 ± 0.437
0.0AsnXaa: 0.0 ± 0.0
Pro
2.992ProAla: 2.992 ± 0.457
0.488ProCys: 0.488 ± 0.196
1.71ProAsp: 1.71 ± 0.341
4.03ProGlu: 4.03 ± 0.783
1.587ProPhe: 1.587 ± 0.313
2.87ProGly: 2.87 ± 0.377
0.794ProHis: 0.794 ± 0.228
3.053ProIle: 3.053 ± 0.616
2.687ProLys: 2.687 ± 0.429
3.114ProLeu: 3.114 ± 0.446
0.427ProMet: 0.427 ± 0.163
2.198ProAsn: 2.198 ± 0.415
1.526ProPro: 1.526 ± 0.355
1.526ProGln: 1.526 ± 0.36
1.099ProArg: 1.099 ± 0.266
2.259ProSer: 2.259 ± 0.43
2.687ProThr: 2.687 ± 0.428
3.725ProVal: 3.725 ± 0.53
0.427ProTrp: 0.427 ± 0.13
2.137ProTyr: 2.137 ± 0.383
0.0ProXaa: 0.0 ± 0.0
Gln
3.175GlnAla: 3.175 ± 0.586
0.427GlnCys: 0.427 ± 0.161
1.099GlnAsp: 1.099 ± 0.286
2.259GlnGlu: 2.259 ± 0.459
1.038GlnPhe: 1.038 ± 0.27
2.259GlnGly: 2.259 ± 0.514
0.611GlnHis: 0.611 ± 0.236
1.771GlnIle: 1.771 ± 0.286
3.175GlnLys: 3.175 ± 0.442
2.687GlnLeu: 2.687 ± 0.462
1.038GlnMet: 1.038 ± 0.257
1.893GlnAsn: 1.893 ± 0.403
1.465GlnPro: 1.465 ± 0.389
1.465GlnGln: 1.465 ± 0.386
1.526GlnArg: 1.526 ± 0.311
2.381GlnSer: 2.381 ± 0.445
2.076GlnThr: 2.076 ± 0.449
2.076GlnVal: 2.076 ± 0.442
0.488GlnTrp: 0.488 ± 0.185
1.221GlnTyr: 1.221 ± 0.288
0.0GlnXaa: 0.0 ± 0.0
Arg
2.87ArgAla: 2.87 ± 0.441
0.672ArgCys: 0.672 ± 0.265
2.32ArgAsp: 2.32 ± 0.323
3.358ArgGlu: 3.358 ± 0.473
2.137ArgPhe: 2.137 ± 0.306
1.771ArgGly: 1.771 ± 0.296
0.916ArgHis: 0.916 ± 0.272
3.602ArgIle: 3.602 ± 0.535
3.541ArgLys: 3.541 ± 0.67
4.152ArgLeu: 4.152 ± 0.461
1.343ArgMet: 1.343 ± 0.291
2.198ArgAsn: 2.198 ± 0.395
1.71ArgPro: 1.71 ± 0.284
1.71ArgGln: 1.71 ± 0.339
2.748ArgArg: 2.748 ± 0.444
2.32ArgSer: 2.32 ± 0.453
2.259ArgThr: 2.259 ± 0.445
2.564ArgVal: 2.564 ± 0.353
0.305ArgTrp: 0.305 ± 0.148
1.649ArgTyr: 1.649 ± 0.307
0.0ArgXaa: 0.0 ± 0.0
Ser
4.396SerAla: 4.396 ± 0.709
0.977SerCys: 0.977 ± 0.283
3.602SerAsp: 3.602 ± 0.398
3.725SerGlu: 3.725 ± 0.418
2.503SerPhe: 2.503 ± 0.345
6.106SerGly: 6.106 ± 0.772
0.733SerHis: 0.733 ± 0.179
4.457SerIle: 4.457 ± 0.556
3.541SerLys: 3.541 ± 0.58
5.678SerLeu: 5.678 ± 0.697
1.771SerMet: 1.771 ± 0.399
4.152SerAsn: 4.152 ± 0.662
3.175SerPro: 3.175 ± 0.564
2.442SerGln: 2.442 ± 0.377
2.259SerArg: 2.259 ± 0.315
3.786SerSer: 3.786 ± 0.727
4.213SerThr: 4.213 ± 0.55
4.579SerVal: 4.579 ± 0.373
0.672SerTrp: 0.672 ± 0.271
2.381SerTyr: 2.381 ± 0.389
0.0SerXaa: 0.0 ± 0.0
Thr
4.946ThrAla: 4.946 ± 0.951
0.794ThrCys: 0.794 ± 0.271
2.748ThrAsp: 2.748 ± 0.414
3.541ThrGlu: 3.541 ± 0.457
2.442ThrPhe: 2.442 ± 0.34
5.923ThrGly: 5.923 ± 1.451
1.343ThrHis: 1.343 ± 0.318
4.946ThrIle: 4.946 ± 0.604
4.213ThrLys: 4.213 ± 0.735
4.091ThrLeu: 4.091 ± 0.635
1.526ThrMet: 1.526 ± 0.35
3.053ThrAsn: 3.053 ± 0.493
3.541ThrPro: 3.541 ± 0.568
1.954ThrGln: 1.954 ± 0.405
2.076ThrArg: 2.076 ± 0.388
5.251ThrSer: 5.251 ± 1.059
5.8ThrThr: 5.8 ± 1.168
3.786ThrVal: 3.786 ± 0.507
1.16ThrTrp: 1.16 ± 0.275
2.137ThrTyr: 2.137 ± 0.388
0.0ThrXaa: 0.0 ± 0.0
Val
4.762ValAla: 4.762 ± 1.047
0.977ValCys: 0.977 ± 0.281
3.663ValAsp: 3.663 ± 0.463
3.847ValGlu: 3.847 ± 0.503
2.381ValPhe: 2.381 ± 0.386
5.007ValGly: 5.007 ± 0.6
0.611ValHis: 0.611 ± 0.19
4.213ValIle: 4.213 ± 0.768
4.03ValLys: 4.03 ± 0.541
4.762ValLeu: 4.762 ± 0.459
1.832ValMet: 1.832 ± 0.357
2.442ValAsn: 2.442 ± 0.434
2.687ValPro: 2.687 ± 0.351
1.71ValGln: 1.71 ± 0.298
2.137ValArg: 2.137 ± 0.269
4.457ValSer: 4.457 ± 0.478
3.602ValThr: 3.602 ± 0.566
3.541ValVal: 3.541 ± 0.455
0.977ValTrp: 0.977 ± 0.315
2.32ValTyr: 2.32 ± 0.368
0.0ValXaa: 0.0 ± 0.0
Trp
0.916TrpAla: 0.916 ± 0.252
0.122TrpCys: 0.122 ± 0.082
0.733TrpAsp: 0.733 ± 0.228
0.427TrpGlu: 0.427 ± 0.175
0.488TrpPhe: 0.488 ± 0.206
0.977TrpGly: 0.977 ± 0.278
0.488TrpHis: 0.488 ± 0.173
0.672TrpIle: 0.672 ± 0.231
0.916TrpLys: 0.916 ± 0.23
1.343TrpLeu: 1.343 ± 0.273
0.366TrpMet: 0.366 ± 0.197
0.611TrpAsn: 0.611 ± 0.18
0.305TrpPro: 0.305 ± 0.148
0.733TrpGln: 0.733 ± 0.196
1.16TrpArg: 1.16 ± 0.398
0.855TrpSer: 0.855 ± 0.299
0.977TrpThr: 0.977 ± 0.573
0.977TrpVal: 0.977 ± 0.229
0.244TrpTrp: 0.244 ± 0.122
0.488TrpTyr: 0.488 ± 0.165
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.992TyrAla: 2.992 ± 0.401
0.977TyrCys: 0.977 ± 0.269
2.259TyrAsp: 2.259 ± 0.334
2.625TyrGlu: 2.625 ± 0.363
1.526TyrPhe: 1.526 ± 0.419
3.114TyrGly: 3.114 ± 0.567
1.099TyrHis: 1.099 ± 0.316
2.687TyrIle: 2.687 ± 0.536
2.809TyrLys: 2.809 ± 0.423
3.725TyrLeu: 3.725 ± 0.474
0.611TyrMet: 0.611 ± 0.198
3.725TyrAsn: 3.725 ± 0.568
1.71TyrPro: 1.71 ± 0.344
1.526TyrGln: 1.526 ± 0.265
1.771TyrArg: 1.771 ± 0.327
2.076TyrSer: 2.076 ± 0.431
1.282TyrThr: 1.282 ± 0.254
2.259TyrVal: 2.259 ± 0.387
0.488TyrTrp: 0.488 ± 0.178
1.404TyrTyr: 1.404 ± 0.322
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 85 proteins (16379 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski