Amino acid dipepetide frequency for Babjeviella inositovora NRRL Y-12698

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.256AlaAla: 7.256 ± 0.081	0.922AlaCys: 0.922 ± 0.022	3.785AlaAsp: 3.785 ± 0.047	4.954AlaGlu: 4.954 ± 0.064	3.042AlaPhe: 3.042 ± 0.037	4.397AlaGly: 4.397 ± 0.046	1.692AlaHis: 1.692 ± 0.026	4.244AlaIle: 4.244 ± 0.043	4.879AlaLys: 4.879 ± 0.056	7.699AlaLeu: 7.699 ± 0.063	1.735AlaMet: 1.735 ± 0.025	3.288AlaAsn: 3.288 ± 0.038	3.833AlaPro: 3.833 ± 0.055	3.005AlaGln: 3.005 ± 0.036	4.103AlaArg: 4.103 ± 0.051	6.509AlaSer: 6.509 ± 0.066	4.904AlaThr: 4.904 ± 0.048	5.266AlaVal: 5.266 ± 0.046	0.745AlaTrp: 0.745 ± 0.019	2.34AlaTyr: 2.34 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.844CysAla: 0.844 ± 0.02	0.246CysCys: 0.246 ± 0.01	0.666CysAsp: 0.666 ± 0.018	0.613CysGlu: 0.613 ± 0.017	0.674CysPhe: 0.674 ± 0.017	0.945CysGly: 0.945 ± 0.02	0.351CysHis: 0.351 ± 0.013	0.768CysIle: 0.768 ± 0.018	0.55CysLys: 0.55 ± 0.015	1.375CysLeu: 1.375 ± 0.024	0.287CysMet: 0.287 ± 0.01	0.463CysAsn: 0.463 ± 0.013	0.534CysPro: 0.534 ± 0.016	0.412CysGln: 0.412 ± 0.013	0.551CysArg: 0.551 ± 0.016	0.841CysSer: 0.841 ± 0.022	0.663CysThr: 0.663 ± 0.019	0.889CysVal: 0.889 ± 0.018	0.174CysTrp: 0.174 ± 0.008	0.459CysTyr: 0.459 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.343AspAla: 4.343 ± 0.05	0.586AspCys: 0.586 ± 0.015	3.743AspAsp: 3.743 ± 0.053	4.507AspGlu: 4.507 ± 0.05	2.543AspPhe: 2.543 ± 0.03	3.093AspGly: 3.093 ± 0.04	1.087AspHis: 1.087 ± 0.021	3.273AspIle: 3.273 ± 0.035	2.683AspLys: 2.683 ± 0.036	5.552AspLeu: 5.552 ± 0.046	1.214AspMet: 1.214 ± 0.022	2.019AspAsn: 2.019 ± 0.028	2.584AspPro: 2.584 ± 0.034	1.594AspGln: 1.594 ± 0.025	2.278AspArg: 2.278 ± 0.03	4.107AspSer: 4.107 ± 0.057	3.081AspThr: 3.081 ± 0.037	3.846AspVal: 3.846 ± 0.041	0.627AspTrp: 0.627 ± 0.015	1.927AspTyr: 1.927 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	5.167GluAla: 5.167 ± 0.051	0.655GluCys: 0.655 ± 0.017	3.7GluAsp: 3.7 ± 0.047	5.511GluGlu: 5.511 ± 0.078	2.718GluPhe: 2.718 ± 0.03	3.067GluGly: 3.067 ± 0.037	1.246GluHis: 1.246 ± 0.029	3.856GluIle: 3.856 ± 0.041	4.174GluLys: 4.174 ± 0.053	6.484GluLeu: 6.484 ± 0.055	1.554GluMet: 1.554 ± 0.022	2.746GluAsn: 2.746 ± 0.032	2.297GluPro: 2.297 ± 0.034	2.206GluGln: 2.206 ± 0.03	3.216GluArg: 3.216 ± 0.038	4.403GluSer: 4.403 ± 0.049	4.047GluThr: 4.047 ± 0.043	4.05GluVal: 4.05 ± 0.044	0.692GluTrp: 0.692 ± 0.017	2.117GluTyr: 2.117 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.244PheAla: 3.244 ± 0.042	0.542PheCys: 0.542 ± 0.015	2.601PheAsp: 2.601 ± 0.032	2.51PheGlu: 2.51 ± 0.033	1.955PhePhe: 1.955 ± 0.032	2.962PheGly: 2.962 ± 0.04	1.066PheHis: 1.066 ± 0.018	2.21PheIle: 2.21 ± 0.027	2.29PheLys: 2.29 ± 0.032	4.142PheLeu: 4.142 ± 0.043	0.969PheMet: 0.969 ± 0.022	2.024PheAsn: 2.024 ± 0.026	2.044PhePro: 2.044 ± 0.028	1.853PheGln: 1.853 ± 0.027	1.986PheArg: 1.986 ± 0.032	3.498PheSer: 3.498 ± 0.037	2.566PheThr: 2.566 ± 0.032	3.011PheVal: 3.011 ± 0.035	0.541PheTrp: 0.541 ± 0.014	1.46PheTyr: 1.46 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	4.253GlyAla: 4.253 ± 0.047	0.803GlyCys: 0.803 ± 0.018	3.104GlyAsp: 3.104 ± 0.035	3.468GlyGlu: 3.468 ± 0.042	2.872GlyPhe: 2.872 ± 0.039	3.902GlyGly: 3.902 ± 0.056	1.257GlyHis: 1.257 ± 0.025	3.487GlyIle: 3.487 ± 0.041	3.506GlyLys: 3.506 ± 0.04	5.797GlyLeu: 5.797 ± 0.05	1.319GlyMet: 1.319 ± 0.023	2.441GlyAsn: 2.441 ± 0.031	2.023GlyPro: 2.023 ± 0.026	1.714GlyGln: 1.714 ± 0.028	2.59GlyArg: 2.59 ± 0.039	4.819GlySer: 4.819 ± 0.054	3.332GlyThr: 3.332 ± 0.035	4.228GlyVal: 4.228 ± 0.044	0.732GlyTrp: 0.732 ± 0.019	2.202GlyTyr: 2.202 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	1.593HisAla: 1.593 ± 0.027	0.318HisCys: 0.318 ± 0.012	1.172HisAsp: 1.172 ± 0.022	1.27HisGlu: 1.27 ± 0.024	1.005HisPhe: 1.005 ± 0.02	1.381HisGly: 1.381 ± 0.026	0.682HisHis: 0.682 ± 0.019	1.295HisIle: 1.295 ± 0.022	1.188HisLys: 1.188 ± 0.023	2.332HisLeu: 2.332 ± 0.031	0.483HisMet: 0.483 ± 0.014	0.966HisAsn: 0.966 ± 0.019	1.308HisPro: 1.308 ± 0.023	0.958HisGln: 0.958 ± 0.021	1.193HisArg: 1.193 ± 0.021	1.827HisSer: 1.827 ± 0.032	1.351HisThr: 1.351 ± 0.021	1.408HisVal: 1.408 ± 0.023	0.266HisTrp: 0.266 ± 0.01	0.801HisTyr: 0.801 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	4.13IleAla: 4.13 ± 0.045	0.718IleCys: 0.718 ± 0.018	3.248IleAsp: 3.248 ± 0.033	3.137IleGlu: 3.137 ± 0.038	2.257IlePhe: 2.257 ± 0.035	3.044IleGly: 3.044 ± 0.044	1.358IleHis: 1.358 ± 0.02	2.9IleIle: 2.9 ± 0.04	2.956IleLys: 2.956 ± 0.034	5.161IleLeu: 5.161 ± 0.045	1.156IleMet: 1.156 ± 0.021	2.36IleAsn: 2.36 ± 0.033	3.036IlePro: 3.036 ± 0.03	2.095IleGln: 2.095 ± 0.029	2.573IleArg: 2.573 ± 0.033	4.506IleSer: 4.506 ± 0.045	3.324IleThr: 3.324 ± 0.039	3.646IleVal: 3.646 ± 0.044	0.605IleTrp: 0.605 ± 0.016	1.727IleTyr: 1.727 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.445LysAla: 4.445 ± 0.055	0.64LysCys: 0.64 ± 0.016	2.884LysAsp: 2.884 ± 0.031	3.703LysGlu: 3.703 ± 0.05	2.409LysPhe: 2.409 ± 0.028	2.773LysGly: 2.773 ± 0.037	1.397LysHis: 1.397 ± 0.023	3.225LysIle: 3.225 ± 0.039	4.409LysLys: 4.409 ± 0.063	6.113LysLeu: 6.113 ± 0.057	1.32LysMet: 1.32 ± 0.024	2.469LysAsn: 2.469 ± 0.033	2.911LysPro: 2.911 ± 0.042	2.317LysGln: 2.317 ± 0.031	3.369LysArg: 3.369 ± 0.042	3.994LysSer: 3.994 ± 0.042	3.503LysThr: 3.503 ± 0.035	3.757LysVal: 3.757 ± 0.041	0.679LysTrp: 0.679 ± 0.017	2.034LysTyr: 2.034 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	8.241LeuAla: 8.241 ± 0.066	1.37LeuCys: 1.37 ± 0.024	5.392LeuAsp: 5.392 ± 0.048	6.217LeuGlu: 6.217 ± 0.057	4.106LeuPhe: 4.106 ± 0.043	5.711LeuGly: 5.711 ± 0.055	2.315LeuHis: 2.315 ± 0.032	4.769LeuIle: 4.769 ± 0.052	5.909LeuLys: 5.909 ± 0.051	10.022LeuLeu: 10.022 ± 0.094	2.166LeuMet: 2.166 ± 0.032	4.49LeuAsn: 4.49 ± 0.044	5.214LeuPro: 5.214 ± 0.052	4.16LeuGln: 4.16 ± 0.039	5.264LeuArg: 5.264 ± 0.049	8.304LeuSer: 8.304 ± 0.067	5.836LeuThr: 5.836 ± 0.055	7.029LeuVal: 7.029 ± 0.067	0.981LeuTrp: 0.981 ± 0.023	3.056LeuTyr: 3.056 ± 0.034	0.0LeuXaa: 0.0 ± 0.0
Met	1.84MetAla: 1.84 ± 0.029	0.31MetCys: 0.31 ± 0.011	1.283MetAsp: 1.283 ± 0.022	1.395MetGlu: 1.395 ± 0.021	0.905MetPhe: 0.905 ± 0.02	1.358MetGly: 1.358 ± 0.027	0.397MetHis: 0.397 ± 0.012	1.028MetIle: 1.028 ± 0.02	1.271MetLys: 1.271 ± 0.02	2.066MetLeu: 2.066 ± 0.032	0.51MetMet: 0.51 ± 0.016	1.033MetAsn: 1.033 ± 0.021	0.996MetPro: 0.996 ± 0.02	0.67MetGln: 0.67 ± 0.017	1.034MetArg: 1.034 ± 0.018	1.929MetSer: 1.929 ± 0.027	1.239MetThr: 1.239 ± 0.02	1.543MetVal: 1.543 ± 0.023	0.209MetTrp: 0.209 ± 0.009	0.667MetTyr: 0.667 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.176AsnAla: 3.176 ± 0.04	0.53AsnCys: 0.53 ± 0.015	2.315AsnAsp: 2.315 ± 0.031	2.516AsnGlu: 2.516 ± 0.034	1.901AsnPhe: 1.901 ± 0.029	2.719AsnGly: 2.719 ± 0.034	1.049AsnHis: 1.049 ± 0.025	2.388AsnIle: 2.388 ± 0.03	2.226AsnLys: 2.226 ± 0.032	4.272AsnLeu: 4.272 ± 0.045	0.924AsnMet: 0.924 ± 0.02	1.89AsnAsn: 1.89 ± 0.034	2.442AsnPro: 2.442 ± 0.03	1.554AsnGln: 1.554 ± 0.031	1.915AsnArg: 1.915 ± 0.028	3.27AsnSer: 3.27 ± 0.035	2.466AsnThr: 2.466 ± 0.03	2.861AsnVal: 2.861 ± 0.034	0.531AsnTrp: 0.531 ± 0.014	1.544AsnTyr: 1.544 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	3.913ProAla: 3.913 ± 0.05	0.411ProCys: 0.411 ± 0.013	2.398ProAsp: 2.398 ± 0.027	3.658ProGlu: 3.658 ± 0.044	2.04ProPhe: 2.04 ± 0.028	2.659ProGly: 2.659 ± 0.035	1.118ProHis: 1.118 ± 0.022	2.362ProIle: 2.362 ± 0.033	2.815ProLys: 2.815 ± 0.038	4.791ProLeu: 4.791 ± 0.053	0.889ProMet: 0.889 ± 0.019	1.95ProAsn: 1.95 ± 0.028	3.048ProPro: 3.048 ± 0.074	2.199ProGln: 2.199 ± 0.042	2.348ProArg: 2.348 ± 0.035	4.189ProSer: 4.189 ± 0.059	2.987ProThr: 2.987 ± 0.04	3.795ProVal: 3.795 ± 0.043	0.478ProTrp: 0.478 ± 0.013	1.481ProTyr: 1.481 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	2.907GlnAla: 2.907 ± 0.034	0.444GlnCys: 0.444 ± 0.013	1.687GlnAsp: 1.687 ± 0.024	2.35GlnGlu: 2.35 ± 0.031	1.664GlnPhe: 1.664 ± 0.026	1.956GlnGly: 1.956 ± 0.031	0.893GlnHis: 0.893 ± 0.019	2.096GlnIle: 2.096 ± 0.025	2.224GlnLys: 2.224 ± 0.03	4.125GlnLeu: 4.125 ± 0.039	0.891GlnMet: 0.891 ± 0.019	1.601GlnAsn: 1.601 ± 0.027	1.864GlnPro: 1.864 ± 0.038	2.224GlnGln: 2.224 ± 0.056	1.991GlnArg: 1.991 ± 0.032	2.726GlnSer: 2.726 ± 0.034	2.271GlnThr: 2.271 ± 0.028	2.346GlnVal: 2.346 ± 0.027	0.423GlnTrp: 0.423 ± 0.012	1.296GlnTyr: 1.296 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	3.891ArgAla: 3.891 ± 0.046	0.577ArgCys: 0.577 ± 0.017	2.783ArgAsp: 2.783 ± 0.03	3.272ArgGlu: 3.272 ± 0.046	2.233ArgPhe: 2.233 ± 0.032	2.807ArgGly: 2.807 ± 0.039	1.136ArgHis: 1.136 ± 0.02	2.657ArgIle: 2.657 ± 0.032	3.219ArgLys: 3.219 ± 0.041	5.13ArgLeu: 5.13 ± 0.048	1.095ArgMet: 1.095 ± 0.019	2.196ArgAsn: 2.196 ± 0.028	1.976ArgPro: 1.976 ± 0.031	1.749ArgGln: 1.749 ± 0.026	3.008ArgArg: 3.008 ± 0.039	3.641ArgSer: 3.641 ± 0.046	2.658ArgThr: 2.658 ± 0.032	3.313ArgVal: 3.313 ± 0.036	0.529ArgTrp: 0.529 ± 0.014	1.645ArgTyr: 1.645 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	5.862SerAla: 5.862 ± 0.056	0.863SerCys: 0.863 ± 0.019	4.389SerAsp: 4.389 ± 0.053	4.521SerGlu: 4.521 ± 0.048	3.559SerPhe: 3.559 ± 0.041	4.824SerGly: 4.824 ± 0.052	1.921SerHis: 1.921 ± 0.028	4.273SerIle: 4.273 ± 0.044	4.277SerLys: 4.277 ± 0.046	8.308SerLeu: 8.308 ± 0.074	1.622SerMet: 1.622 ± 0.024	3.182SerAsn: 3.182 ± 0.04	4.376SerPro: 4.376 ± 0.058	3.138SerGln: 3.138 ± 0.038	3.911SerArg: 3.911 ± 0.045	7.697SerSer: 7.697 ± 0.114	4.968SerThr: 4.968 ± 0.059	5.386SerVal: 5.386 ± 0.052	0.811SerTrp: 0.811 ± 0.019	2.411SerTyr: 2.411 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	4.723ThrAla: 4.723 ± 0.044	0.709ThrCys: 0.709 ± 0.017	2.943ThrAsp: 2.943 ± 0.035	3.363ThrGlu: 3.363 ± 0.038	2.515ThrPhe: 2.515 ± 0.029	3.679ThrGly: 3.679 ± 0.04	1.361ThrHis: 1.361 ± 0.021	3.266ThrIle: 3.266 ± 0.04	3.42ThrLys: 3.42 ± 0.033	5.871ThrLeu: 5.871 ± 0.05	1.105ThrMet: 1.105 ± 0.022	2.54ThrAsn: 2.54 ± 0.033	3.731ThrPro: 3.731 ± 0.047	2.122ThrGln: 2.122 ± 0.03	2.865ThrArg: 2.865 ± 0.037	5.049ThrSer: 5.049 ± 0.052	3.805ThrThr: 3.805 ± 0.054	4.119ThrVal: 4.119 ± 0.047	0.61ThrTrp: 0.61 ± 0.016	1.839ThrTyr: 1.839 ± 0.027	0.0ThrXaa: 0.0 ± 0.0
Val	5.639ValAla: 5.639 ± 0.054	0.946ValCys: 0.946 ± 0.018	3.88ValAsp: 3.88 ± 0.041	4.379ValGlu: 4.379 ± 0.041	3.034ValPhe: 3.034 ± 0.037	3.811ValGly: 3.811 ± 0.042	1.43ValHis: 1.43 ± 0.024	3.471ValIle: 3.471 ± 0.035	3.929ValLys: 3.929 ± 0.04	6.781ValLeu: 6.781 ± 0.06	1.465ValMet: 1.465 ± 0.025	2.759ValAsn: 2.759 ± 0.034	3.458ValPro: 3.458 ± 0.043	2.336ValGln: 2.336 ± 0.034	3.171ValArg: 3.171 ± 0.04	5.765ValSer: 5.765 ± 0.047	4.047ValThr: 4.047 ± 0.045	5.128ValVal: 5.128 ± 0.053	0.737ValTrp: 0.737 ± 0.02	2.317ValTyr: 2.317 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	0.702TrpAla: 0.702 ± 0.018	0.231TrpCys: 0.231 ± 0.008	0.668TrpAsp: 0.668 ± 0.018	0.651TrpGlu: 0.651 ± 0.017	0.546TrpPhe: 0.546 ± 0.016	0.705TrpGly: 0.705 ± 0.017	0.238TrpHis: 0.238 ± 0.009	0.598TrpIle: 0.598 ± 0.015	0.705TrpLys: 0.705 ± 0.015	1.107TrpLeu: 1.107 ± 0.024	0.28TrpMet: 0.28 ± 0.011	0.54TrpAsn: 0.54 ± 0.015	0.341TrpPro: 0.341 ± 0.011	0.36TrpGln: 0.36 ± 0.012	0.594TrpArg: 0.594 ± 0.015	0.823TrpSer: 0.823 ± 0.02	0.583TrpThr: 0.583 ± 0.016	0.701TrpVal: 0.701 ± 0.017	0.192TrpTrp: 0.192 ± 0.008	0.394TrpTyr: 0.394 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.429TyrAla: 2.429 ± 0.031	0.487TyrCys: 0.487 ± 0.012	2.046TyrAsp: 2.046 ± 0.03	1.909TyrGlu: 1.909 ± 0.027	1.498TyrPhe: 1.498 ± 0.025	2.055TyrGly: 2.055 ± 0.029	0.798TyrHis: 0.798 ± 0.018	1.77TyrIle: 1.77 ± 0.029	1.722TyrLys: 1.722 ± 0.025	3.426TyrLeu: 3.426 ± 0.036	0.698TyrMet: 0.698 ± 0.015	1.533TyrAsn: 1.533 ± 0.028	1.512TyrPro: 1.512 ± 0.029	1.314TyrGln: 1.314 ± 0.026	1.556TyrArg: 1.556 ± 0.023	2.401TyrSer: 2.401 ± 0.034	2.004TyrThr: 2.004 ± 0.03	2.161TyrVal: 2.161 ± 0.026	0.398TyrTrp: 0.398 ± 0.011	1.264TyrTyr: 1.264 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6394 proteins (2766287 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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