Amino acid dipepetide frequency for Ulvibacter antarcticus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.632AlaAla: 4.632 ± 0.082	0.544AlaCys: 0.544 ± 0.024	3.303AlaAsp: 3.303 ± 0.062	3.823AlaGlu: 3.823 ± 0.062	3.297AlaPhe: 3.297 ± 0.056	4.495AlaGly: 4.495 ± 0.095	1.097AlaHis: 1.097 ± 0.032	5.51AlaIle: 5.51 ± 0.077	4.398AlaLys: 4.398 ± 0.081	6.052AlaLeu: 6.052 ± 0.078	1.63AlaMet: 1.63 ± 0.044	3.605AlaAsn: 3.605 ± 0.057	1.989AlaPro: 1.989 ± 0.051	2.369AlaGln: 2.369 ± 0.042	2.037AlaArg: 2.037 ± 0.057	4.875AlaSer: 4.875 ± 0.095	4.133AlaThr: 4.133 ± 0.087	4.286AlaVal: 4.286 ± 0.074	0.56AlaTrp: 0.56 ± 0.026	2.43AlaTyr: 2.43 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.462CysAla: 0.462 ± 0.019	0.097CysCys: 0.097 ± 0.01	0.506CysAsp: 0.506 ± 0.031	0.471CysGlu: 0.471 ± 0.024	0.433CysPhe: 0.433 ± 0.023	0.605CysGly: 0.605 ± 0.025	0.205CysHis: 0.205 ± 0.033	0.615CysIle: 0.615 ± 0.026	0.465CysLys: 0.465 ± 0.02	0.679CysLeu: 0.679 ± 0.026	0.144CysMet: 0.144 ± 0.012	0.446CysAsn: 0.446 ± 0.02	0.342CysPro: 0.342 ± 0.022	0.176CysGln: 0.176 ± 0.014	0.219CysArg: 0.219 ± 0.013	0.574CysSer: 0.574 ± 0.026	0.493CysThr: 0.493 ± 0.025	0.455CysVal: 0.455 ± 0.022	0.064CysTrp: 0.064 ± 0.013	0.29CysTyr: 0.29 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.973AspAla: 3.973 ± 0.067	0.528AspCys: 0.528 ± 0.032	3.209AspAsp: 3.209 ± 0.065	3.699AspGlu: 3.699 ± 0.068	3.602AspPhe: 3.602 ± 0.067	4.182AspGly: 4.182 ± 0.094	0.969AspHis: 0.969 ± 0.028	4.575AspIle: 4.575 ± 0.066	3.615AspLys: 3.615 ± 0.065	5.239AspLeu: 5.239 ± 0.069	1.094AspMet: 1.094 ± 0.03	3.13AspAsn: 3.13 ± 0.07	2.066AspPro: 2.066 ± 0.06	1.614AspGln: 1.614 ± 0.045	1.964AspArg: 1.964 ± 0.041	3.48AspSer: 3.48 ± 0.059	3.001AspThr: 3.001 ± 0.061	3.812AspVal: 3.812 ± 0.067	0.718AspTrp: 0.718 ± 0.021	2.679AspTyr: 2.679 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.98GluAla: 4.98 ± 0.079	0.383GluCys: 0.383 ± 0.027	3.633GluAsp: 3.633 ± 0.06	4.775GluGlu: 4.775 ± 0.093	2.958GluPhe: 2.958 ± 0.058	3.963GluGly: 3.963 ± 0.062	1.094GluHis: 1.094 ± 0.028	5.837GluIle: 5.837 ± 0.083	5.732GluLys: 5.732 ± 0.088	6.132GluLeu: 6.132 ± 0.087	1.714GluMet: 1.714 ± 0.04	4.724GluAsn: 4.724 ± 0.072	1.472GluPro: 1.472 ± 0.041	2.099GluGln: 2.099 ± 0.051	2.447GluArg: 2.447 ± 0.051	3.469GluSer: 3.469 ± 0.054	3.891GluThr: 3.891 ± 0.059	4.419GluVal: 4.419 ± 0.063	0.553GluTrp: 0.553 ± 0.02	2.326GluTyr: 2.326 ± 0.053	0.0GluXaa: 0.0 ± 0.0
Phe	3.018PheAla: 3.018 ± 0.048	0.414PheCys: 0.414 ± 0.023	3.269PheAsp: 3.269 ± 0.059	3.402PheGlu: 3.402 ± 0.059	2.659PhePhe: 2.659 ± 0.07	3.751PheGly: 3.751 ± 0.075	0.795PheHis: 0.795 ± 0.025	3.823PheIle: 3.823 ± 0.066	3.39PheLys: 3.39 ± 0.059	4.569PheLeu: 4.569 ± 0.078	1.076PheMet: 1.076 ± 0.031	3.118PheAsn: 3.118 ± 0.058	1.808PhePro: 1.808 ± 0.04	1.583PheGln: 1.583 ± 0.037	1.666PheArg: 1.666 ± 0.042	4.287PheSer: 4.287 ± 0.072	3.184PheThr: 3.184 ± 0.059	3.084PheVal: 3.084 ± 0.053	0.52PheTrp: 0.52 ± 0.023	2.082PheTyr: 2.082 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	4.278GlyAla: 4.278 ± 0.084	0.607GlyCys: 0.607 ± 0.028	3.997GlyAsp: 3.997 ± 0.077	3.624GlyGlu: 3.624 ± 0.061	3.59GlyPhe: 3.59 ± 0.061	5.188GlyGly: 5.188 ± 0.19	1.124GlyHis: 1.124 ± 0.032	5.59GlyIle: 5.59 ± 0.08	4.565GlyLys: 4.565 ± 0.08	5.823GlyLeu: 5.823 ± 0.081	1.717GlyMet: 1.717 ± 0.044	4.269GlyAsn: 4.269 ± 0.105	1.455GlyPro: 1.455 ± 0.039	1.871GlyGln: 1.871 ± 0.046	2.167GlyArg: 2.167 ± 0.046	4.456GlySer: 4.456 ± 0.082	4.513GlyThr: 4.513 ± 0.11	4.49GlyVal: 4.49 ± 0.074	0.74GlyTrp: 0.74 ± 0.028	2.699GlyTyr: 2.699 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	0.927HisAla: 0.927 ± 0.033	0.177HisCys: 0.177 ± 0.013	0.847HisAsp: 0.847 ± 0.032	0.939HisGlu: 0.939 ± 0.029	1.109HisPhe: 1.109 ± 0.039	1.056HisGly: 1.056 ± 0.036	0.462HisHis: 0.462 ± 0.022	1.368HisIle: 1.368 ± 0.037	1.129HisLys: 1.129 ± 0.03	1.717HisLeu: 1.717 ± 0.038	0.317HisMet: 0.317 ± 0.015	0.915HisAsn: 0.915 ± 0.028	0.887HisPro: 0.887 ± 0.031	0.633HisGln: 0.633 ± 0.023	0.652HisArg: 0.652 ± 0.023	1.087HisSer: 1.087 ± 0.037	0.924HisThr: 0.924 ± 0.035	0.817HisVal: 0.817 ± 0.027	0.221HisTrp: 0.221 ± 0.013	0.752HisTyr: 0.752 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.812IleAla: 5.812 ± 0.078	0.647IleCys: 0.647 ± 0.024	4.966IleAsp: 4.966 ± 0.066	5.555IleGlu: 5.555 ± 0.073	3.687IlePhe: 3.687 ± 0.063	5.216IleGly: 5.216 ± 0.073	1.279IleHis: 1.279 ± 0.038	5.926IleIle: 5.926 ± 0.091	5.149IleLys: 5.149 ± 0.074	7.276IleLeu: 7.276 ± 0.105	1.406IleMet: 1.406 ± 0.042	4.372IleAsn: 4.372 ± 0.063	3.268IlePro: 3.268 ± 0.062	2.441IleGln: 2.441 ± 0.051	2.613IleArg: 2.613 ± 0.045	6.153IleSer: 6.153 ± 0.081	4.988IleThr: 4.988 ± 0.087	5.079IleVal: 5.079 ± 0.076	0.694IleTrp: 0.694 ± 0.025	2.779IleTyr: 2.779 ± 0.057	0.0IleXaa: 0.0 ± 0.0
Lys	4.581LysAla: 4.581 ± 0.079	0.342LysCys: 0.342 ± 0.017	4.189LysAsp: 4.189 ± 0.066	5.793LysGlu: 5.793 ± 0.104	2.805LysPhe: 2.805 ± 0.052	4.239LysGly: 4.239 ± 0.076	1.291LysHis: 1.291 ± 0.036	5.753LysIle: 5.753 ± 0.078	6.605LysLys: 6.605 ± 0.096	6.374LysLeu: 6.374 ± 0.087	2.0LysMet: 2.0 ± 0.047	4.7LysAsn: 4.7 ± 0.08	2.124LysPro: 2.124 ± 0.052	2.43LysGln: 2.43 ± 0.044	2.821LysArg: 2.821 ± 0.052	4.425LysSer: 4.425 ± 0.08	4.228LysThr: 4.228 ± 0.069	4.46LysVal: 4.46 ± 0.067	0.663LysTrp: 0.663 ± 0.026	2.613LysTyr: 2.613 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	5.719LeuAla: 5.719 ± 0.078	0.655LeuCys: 0.655 ± 0.026	5.166LeuAsp: 5.166 ± 0.073	6.011LeuGlu: 6.011 ± 0.079	4.926LeuPhe: 4.926 ± 0.084	5.731LeuGly: 5.731 ± 0.079	1.584LeuHis: 1.584 ± 0.041	7.107LeuIle: 7.107 ± 0.116	7.385LeuLys: 7.385 ± 0.108	9.176LeuLeu: 9.176 ± 0.119	2.006LeuMet: 2.006 ± 0.045	5.443LeuAsn: 5.443 ± 0.079	3.369LeuPro: 3.369 ± 0.054	3.323LeuGln: 3.323 ± 0.059	3.272LeuArg: 3.272 ± 0.067	6.897LeuSer: 6.897 ± 0.082	5.173LeuThr: 5.173 ± 0.071	5.335LeuVal: 5.335 ± 0.061	0.84LeuTrp: 0.84 ± 0.032	3.264LeuTyr: 3.264 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	1.685MetAla: 1.685 ± 0.045	0.129MetCys: 0.129 ± 0.011	1.249MetAsp: 1.249 ± 0.031	1.522MetGlu: 1.522 ± 0.038	0.843MetPhe: 0.843 ± 0.027	1.472MetGly: 1.472 ± 0.043	0.404MetHis: 0.404 ± 0.019	1.603MetIle: 1.603 ± 0.041	2.232MetLys: 2.232 ± 0.043	2.089MetLeu: 2.089 ± 0.049	0.612MetMet: 0.612 ± 0.031	1.345MetAsn: 1.345 ± 0.038	0.846MetPro: 0.846 ± 0.032	0.799MetGln: 0.799 ± 0.028	0.893MetArg: 0.893 ± 0.029	1.425MetSer: 1.425 ± 0.037	1.128MetThr: 1.128 ± 0.036	1.384MetVal: 1.384 ± 0.037	0.155MetTrp: 0.155 ± 0.014	0.728MetTyr: 0.728 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.876AsnAla: 3.876 ± 0.061	0.532AsnCys: 0.532 ± 0.026	3.56AsnAsp: 3.56 ± 0.066	3.841AsnGlu: 3.841 ± 0.058	3.047AsnPhe: 3.047 ± 0.059	4.404AsnGly: 4.404 ± 0.103	0.967AsnHis: 0.967 ± 0.031	4.516AsnIle: 4.516 ± 0.076	3.812AsnLys: 3.812 ± 0.071	5.276AsnLeu: 5.276 ± 0.075	1.33AsnMet: 1.33 ± 0.037	3.928AsnAsn: 3.928 ± 0.095	2.81AsnPro: 2.81 ± 0.066	1.874AsnGln: 1.874 ± 0.044	2.2AsnArg: 2.2 ± 0.052	4.067AsnSer: 4.067 ± 0.067	3.765AsnThr: 3.765 ± 0.074	3.653AsnVal: 3.653 ± 0.062	0.742AsnTrp: 0.742 ± 0.026	2.703AsnTyr: 2.703 ± 0.055	0.0AsnXaa: 0.0 ± 0.0
Pro	1.945ProAla: 1.945 ± 0.052	0.233ProCys: 0.233 ± 0.016	2.036ProAsp: 2.036 ± 0.042	2.682ProGlu: 2.682 ± 0.06	1.926ProPhe: 1.926 ± 0.044	2.11ProGly: 2.11 ± 0.047	0.557ProHis: 0.557 ± 0.024	2.746ProIle: 2.746 ± 0.062	2.466ProLys: 2.466 ± 0.054	2.959ProLeu: 2.959 ± 0.051	0.74ProMet: 0.74 ± 0.023	2.28ProAsn: 2.28 ± 0.047	0.906ProPro: 0.906 ± 0.035	1.116ProGln: 1.116 ± 0.031	0.912ProArg: 0.912 ± 0.031	2.33ProSer: 2.33 ± 0.043	1.978ProThr: 1.978 ± 0.061	2.37ProVal: 2.37 ± 0.047	0.316ProTrp: 0.316 ± 0.019	1.297ProTyr: 1.297 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	1.918GlnAla: 1.918 ± 0.046	0.165GlnCys: 0.165 ± 0.012	1.633GlnAsp: 1.633 ± 0.037	2.052GlnGlu: 2.052 ± 0.056	1.615GlnPhe: 1.615 ± 0.035	1.845GlnGly: 1.845 ± 0.042	0.56GlnHis: 0.56 ± 0.021	2.521GlnIle: 2.521 ± 0.051	2.722GlnLys: 2.722 ± 0.056	3.586GlnLeu: 3.586 ± 0.069	0.853GlnMet: 0.853 ± 0.031	2.097GlnAsn: 2.097 ± 0.047	0.978GlnPro: 0.978 ± 0.028	1.371GlnGln: 1.371 ± 0.042	1.161GlnArg: 1.161 ± 0.03	1.971GlnSer: 1.971 ± 0.041	1.93GlnThr: 1.93 ± 0.066	1.761GlnVal: 1.761 ± 0.04	0.346GlnTrp: 0.346 ± 0.018	1.253GlnTyr: 1.253 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.065ArgAla: 2.065 ± 0.049	0.203ArgCys: 0.203 ± 0.012	1.883ArgAsp: 1.883 ± 0.039	2.169ArgGlu: 2.169 ± 0.049	1.893ArgPhe: 1.893 ± 0.045	1.959ArgGly: 1.959 ± 0.046	0.568ArgHis: 0.568 ± 0.025	2.945ArgIle: 2.945 ± 0.057	2.813ArgLys: 2.813 ± 0.054	3.23ArgLeu: 3.23 ± 0.063	0.891ArgMet: 0.891 ± 0.031	2.144ArgAsn: 2.144 ± 0.046	1.058ArgPro: 1.058 ± 0.031	1.049ArgGln: 1.049 ± 0.032	1.355ArgArg: 1.355 ± 0.035	2.08ArgSer: 2.08 ± 0.042	1.916ArgThr: 1.916 ± 0.044	2.035ArgVal: 2.035 ± 0.044	0.364ArgTrp: 0.364 ± 0.018	1.528ArgTyr: 1.528 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	3.889SerAla: 3.889 ± 0.061	0.727SerCys: 0.727 ± 0.033	3.776SerAsp: 3.776 ± 0.062	5.995SerGlu: 5.995 ± 0.088	3.821SerPhe: 3.821 ± 0.066	5.049SerGly: 5.049 ± 0.095	1.036SerHis: 1.036 ± 0.032	5.263SerIle: 5.263 ± 0.073	4.722SerLys: 4.722 ± 0.063	6.144SerLeu: 6.144 ± 0.085	1.427SerMet: 1.427 ± 0.04	4.072SerAsn: 4.072 ± 0.07	2.235SerPro: 2.235 ± 0.046	2.179SerGln: 2.179 ± 0.044	2.107SerArg: 2.107 ± 0.041	4.538SerSer: 4.538 ± 0.086	3.79SerThr: 3.79 ± 0.074	4.194SerVal: 4.194 ± 0.068	0.669SerTrp: 0.669 ± 0.029	2.76SerTyr: 2.76 ± 0.06	0.0SerXaa: 0.0 ± 0.0
Thr	4.102ThrAla: 4.102 ± 0.094	0.361ThrCys: 0.361 ± 0.023	3.346ThrAsp: 3.346 ± 0.079	3.473ThrGlu: 3.473 ± 0.059	3.042ThrPhe: 3.042 ± 0.06	4.352ThrGly: 4.352 ± 0.094	0.945ThrHis: 0.945 ± 0.033	5.18ThrIle: 5.18 ± 0.094	3.588ThrLys: 3.588 ± 0.065	5.423ThrLeu: 5.423 ± 0.066	1.115ThrMet: 1.115 ± 0.035	3.507ThrAsn: 3.507 ± 0.076	2.49ThrPro: 2.49 ± 0.063	1.915ThrGln: 1.915 ± 0.046	1.722ThrArg: 1.722 ± 0.044	4.217ThrSer: 4.217 ± 0.072	3.895ThrThr: 3.895 ± 0.087	4.123ThrVal: 4.123 ± 0.089	0.57ThrTrp: 0.57 ± 0.025	2.409ThrTyr: 2.409 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	4.271ValAla: 4.271 ± 0.071	0.544ValCys: 0.544 ± 0.024	3.637ValAsp: 3.637 ± 0.062	3.897ValGlu: 3.897 ± 0.071	3.319ValPhe: 3.319 ± 0.055	3.945ValGly: 3.945 ± 0.066	1.033ValHis: 1.033 ± 0.028	5.08ValIle: 5.08 ± 0.077	4.168ValLys: 4.168 ± 0.068	5.978ValLeu: 5.978 ± 0.086	1.397ValMet: 1.397 ± 0.037	3.586ValAsn: 3.586 ± 0.066	2.132ValPro: 2.132 ± 0.053	1.766ValGln: 1.766 ± 0.042	1.98ValArg: 1.98 ± 0.044	4.72ValSer: 4.72 ± 0.068	4.015ValThr: 4.015 ± 0.095	4.39ValVal: 4.39 ± 0.081	0.629ValTrp: 0.629 ± 0.026	2.444ValTyr: 2.444 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.598TrpAla: 0.598 ± 0.023	0.087TrpCys: 0.087 ± 0.009	0.567TrpAsp: 0.567 ± 0.021	0.687TrpGlu: 0.687 ± 0.028	0.536TrpPhe: 0.536 ± 0.023	0.614TrpGly: 0.614 ± 0.026	0.218TrpHis: 0.218 ± 0.015	0.709TrpIle: 0.709 ± 0.027	0.727TrpLys: 0.727 ± 0.027	0.906TrpLeu: 0.906 ± 0.027	0.315TrpMet: 0.315 ± 0.018	0.651TrpAsn: 0.651 ± 0.031	0.247TrpPro: 0.247 ± 0.014	0.386TrpGln: 0.386 ± 0.017	0.386TrpArg: 0.386 ± 0.016	0.589TrpSer: 0.589 ± 0.021	0.535TrpThr: 0.535 ± 0.026	0.615TrpVal: 0.615 ± 0.023	0.143TrpTrp: 0.143 ± 0.013	0.429TrpTyr: 0.429 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.334TyrAla: 2.334 ± 0.048	0.366TyrCys: 0.366 ± 0.019	2.374TyrAsp: 2.374 ± 0.06	2.188TyrGlu: 2.188 ± 0.045	2.392TyrPhe: 2.392 ± 0.047	2.587TyrGly: 2.587 ± 0.053	0.749TyrHis: 0.749 ± 0.028	2.636TyrIle: 2.636 ± 0.051	2.754TyrLys: 2.754 ± 0.055	3.754TyrLeu: 3.754 ± 0.065	0.76TyrMet: 0.76 ± 0.028	2.571TyrAsn: 2.571 ± 0.048	1.422TyrPro: 1.422 ± 0.035	1.345TyrGln: 1.345 ± 0.035	1.572TyrArg: 1.572 ± 0.041	2.753TyrSer: 2.753 ± 0.056	2.294TyrThr: 2.294 ± 0.046	2.173TyrVal: 2.173 ± 0.047	0.437TyrTrp: 0.437 ± 0.023	1.792TyrTyr: 1.792 ± 0.056	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3363 proteins (1143827 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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