Amino acid dipepetide frequency for Lily symptomless virus (LSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.764AlaAla: 5.764 ± 2.075
2.522AlaCys: 2.522 ± 0.871
5.043AlaAsp: 5.043 ± 1.059
3.242AlaGlu: 3.242 ± 1.864
5.403AlaPhe: 5.403 ± 1.511
4.683AlaGly: 4.683 ± 1.732
2.882AlaHis: 2.882 ± 2.896
6.124AlaIle: 6.124 ± 1.844
5.043AlaLys: 5.043 ± 2.179
10.086AlaLeu: 10.086 ± 1.952
1.801AlaMet: 1.801 ± 0.925
3.242AlaAsn: 3.242 ± 0.941
2.522AlaPro: 2.522 ± 0.837
2.882AlaGln: 2.882 ± 0.51
5.043AlaArg: 5.043 ± 1.529
5.043AlaSer: 5.043 ± 1.113
3.242AlaThr: 3.242 ± 0.625
2.882AlaVal: 2.882 ± 0.51
1.081AlaTrp: 1.081 ± 0.559
1.441AlaTyr: 1.441 ± 1.307
0.0AlaXaa: 0.0 ± 0.0
Cys
1.441CysAla: 1.441 ± 1.122
0.36CysCys: 0.36 ± 0.186
0.72CysAsp: 0.72 ± 0.705
1.441CysGlu: 1.441 ± 0.978
1.441CysPhe: 1.441 ± 0.745
2.882CysGly: 2.882 ± 1.528
0.36CysHis: 0.36 ± 0.186
1.441CysIle: 1.441 ± 1.307
1.801CysLys: 1.801 ± 0.932
3.242CysLeu: 3.242 ± 0.808
0.36CysMet: 0.36 ± 0.186
0.36CysAsn: 0.36 ± 1.121
0.72CysPro: 0.72 ± 0.373
0.72CysGln: 0.72 ± 0.373
2.522CysArg: 2.522 ± 0.877
1.441CysSer: 1.441 ± 0.745
4.323CysThr: 4.323 ± 1.155
1.081CysVal: 1.081 ± 0.469
0.36CysTrp: 0.36 ± 0.79
1.081CysTyr: 1.081 ± 0.663
0.0CysXaa: 0.0 ± 0.0
Asp
2.522AspAla: 2.522 ± 0.446
2.161AspCys: 2.161 ± 0.643
1.441AspAsp: 1.441 ± 0.745
6.844AspGlu: 6.844 ± 1.364
1.801AspPhe: 1.801 ± 0.932
2.522AspGly: 2.522 ± 1.009
0.72AspHis: 0.72 ± 0.705
3.602AspIle: 3.602 ± 1.251
1.441AspLys: 1.441 ± 0.745
3.602AspLeu: 3.602 ± 1.96
0.72AspMet: 0.72 ± 0.538
2.522AspAsn: 2.522 ± 0.951
2.161AspPro: 2.161 ± 0.455
0.72AspGln: 0.72 ± 0.373
2.522AspArg: 2.522 ± 1.097
1.441AspSer: 1.441 ± 0.533
1.441AspThr: 1.441 ± 0.754
2.882AspVal: 2.882 ± 1.06
0.72AspTrp: 0.72 ± 0.474
2.161AspTyr: 2.161 ± 0.754
0.0AspXaa: 0.0 ± 0.0
Glu
6.124GluAla: 6.124 ± 1.944
0.72GluCys: 0.72 ± 0.373
1.801GluAsp: 1.801 ± 0.559
3.963GluGlu: 3.963 ± 2.05
3.963GluPhe: 3.963 ± 0.86
3.242GluGly: 3.242 ± 0.732
1.801GluHis: 1.801 ± 0.647
4.683GluIle: 4.683 ± 0.639
4.323GluLys: 4.323 ± 1.577
5.403GluLeu: 5.403 ± 1.074
1.801GluMet: 1.801 ± 0.932
1.801GluAsn: 1.801 ± 0.534
3.602GluPro: 3.602 ± 1.294
3.242GluGln: 3.242 ± 1.171
4.323GluArg: 4.323 ± 0.643
6.124GluSer: 6.124 ± 1.927
3.242GluThr: 3.242 ± 0.732
3.963GluVal: 3.963 ± 1.074
1.081GluTrp: 1.081 ± 0.559
1.081GluTyr: 1.081 ± 1.457
0.0GluXaa: 0.0 ± 0.0
Phe
4.323PheAla: 4.323 ± 0.893
0.36PheCys: 0.36 ± 0.186
2.522PheAsp: 2.522 ± 0.837
5.764PheGlu: 5.764 ± 1.02
1.081PhePhe: 1.081 ± 0.737
3.242PheGly: 3.242 ± 1.695
0.36PheHis: 0.36 ± 0.186
2.161PheIle: 2.161 ± 0.643
2.882PheLys: 2.882 ± 1.112
5.403PheLeu: 5.403 ± 2.362
0.72PheMet: 0.72 ± 0.373
1.441PheAsn: 1.441 ± 0.745
0.72PhePro: 0.72 ± 0.705
2.522PheGln: 2.522 ± 0.871
1.801PheArg: 1.801 ± 0.905
3.963PheSer: 3.963 ± 0.861
2.522PheThr: 2.522 ± 1.009
2.522PheVal: 2.522 ± 1.08
0.36PheTrp: 0.36 ± 0.186
1.441PheTyr: 1.441 ± 0.672
0.0PheXaa: 0.0 ± 0.0
Gly
6.484GlyAla: 6.484 ± 1.485
0.72GlyCys: 0.72 ± 1.022
3.242GlyAsp: 3.242 ± 0.912
3.963GlyGlu: 3.963 ± 1.498
1.801GlyPhe: 1.801 ± 0.559
4.323GlyGly: 4.323 ± 1.788
1.801GlyHis: 1.801 ± 0.801
2.522GlyIle: 2.522 ± 0.946
2.522GlyLys: 2.522 ± 1.08
5.043GlyLeu: 5.043 ± 2.678
0.72GlyMet: 0.72 ± 0.404
2.522GlyAsn: 2.522 ± 0.764
1.801GlyPro: 1.801 ± 1.707
1.441GlyGln: 1.441 ± 0.978
7.205GlyArg: 7.205 ± 2.252
3.602GlySer: 3.602 ± 1.476
3.242GlyThr: 3.242 ± 0.912
5.043GlyVal: 5.043 ± 1.001
1.081GlyTrp: 1.081 ± 0.559
2.882GlyTyr: 2.882 ± 1.076
0.0GlyXaa: 0.0 ± 0.0
His
2.522HisAla: 2.522 ± 0.446
0.0HisCys: 0.0 ± 0.0
0.72HisAsp: 0.72 ± 0.373
0.72HisGlu: 0.72 ± 0.373
1.081HisPhe: 1.081 ± 1.428
1.441HisGly: 1.441 ± 1.01
0.36HisHis: 0.36 ± 0.186
0.72HisIle: 0.72 ± 1.58
1.441HisLys: 1.441 ± 0.533
3.963HisLeu: 3.963 ± 1.835
0.36HisMet: 0.36 ± 0.778
1.801HisAsn: 1.801 ± 1.96
0.72HisPro: 0.72 ± 0.373
0.0HisGln: 0.0 ± 0.0
2.161HisArg: 2.161 ± 1.695
3.242HisSer: 3.242 ± 1.073
1.081HisThr: 1.081 ± 0.559
1.081HisVal: 1.081 ± 0.469
0.0HisTrp: 0.0 ± 0.0
0.72HisTyr: 0.72 ± 0.373
0.0HisXaa: 0.0 ± 0.0
Ile
4.683IleAla: 4.683 ± 2.147
1.801IleCys: 1.801 ± 0.731
5.043IleAsp: 5.043 ± 1.529
4.323IleGlu: 4.323 ± 0.899
2.161IlePhe: 2.161 ± 1.118
2.522IleGly: 2.522 ± 1.302
0.72IleHis: 0.72 ± 0.373
5.403IleIle: 5.403 ± 1.023
3.963IleLys: 3.963 ± 1.19
4.323IleLeu: 4.323 ± 0.643
2.882IleMet: 2.882 ± 0.94
3.242IleAsn: 3.242 ± 1.196
2.161IlePro: 2.161 ± 0.792
1.441IleGln: 1.441 ± 0.658
3.602IleArg: 3.602 ± 1.444
1.801IleSer: 1.801 ± 1.676
3.963IleThr: 3.963 ± 1.097
4.323IleVal: 4.323 ± 2.374
0.0IleTrp: 0.0 ± 0.0
1.441IleTyr: 1.441 ± 0.745
0.0IleXaa: 0.0 ± 0.0
Lys
3.602LysAla: 3.602 ± 1.229
0.72LysCys: 0.72 ± 1.251
1.801LysAsp: 1.801 ± 0.559
2.882LysGlu: 2.882 ± 1.093
2.522LysPhe: 2.522 ± 1.305
3.242LysGly: 3.242 ± 1.677
2.522LysHis: 2.522 ± 0.987
2.882LysIle: 2.882 ± 1.112
3.963LysLys: 3.963 ± 0.927
4.323LysLeu: 4.323 ± 0.785
1.081LysMet: 1.081 ± 0.757
1.801LysAsn: 1.801 ± 0.932
2.161LysPro: 2.161 ± 0.827
1.441LysGln: 1.441 ± 0.533
3.963LysArg: 3.963 ± 1.009
3.242LysSer: 3.242 ± 0.959
3.963LysThr: 3.963 ± 1.575
2.522LysVal: 2.522 ± 1.304
0.36LysTrp: 0.36 ± 0.186
3.602LysTyr: 3.602 ± 1.864
0.0LysXaa: 0.0 ± 0.0
Leu
5.043LeuAla: 5.043 ± 0.96
3.242LeuCys: 3.242 ± 1.095
4.683LeuAsp: 4.683 ± 1.732
6.124LeuGlu: 6.124 ± 1.628
3.242LeuPhe: 3.242 ± 1.284
6.484LeuGly: 6.484 ± 0.677
0.72LeuHis: 0.72 ± 0.373
4.323LeuIle: 4.323 ± 2.475
5.764LeuLys: 5.764 ± 1.779
11.527LeuLeu: 11.527 ± 2.163
1.081LeuMet: 1.081 ± 0.799
5.043LeuAsn: 5.043 ± 1.022
6.124LeuPro: 6.124 ± 1.919
6.844LeuGln: 6.844 ± 2.088
6.124LeuArg: 6.124 ± 1.166
5.764LeuSer: 5.764 ± 3.923
6.484LeuThr: 6.484 ± 1.104
7.205LeuVal: 7.205 ± 2.062
0.36LeuTrp: 0.36 ± 0.186
2.882LeuTyr: 2.882 ± 0.51
0.0LeuXaa: 0.0 ± 0.0
Met
3.963MetAla: 3.963 ± 1.43
1.081MetCys: 1.081 ± 0.469
1.441MetAsp: 1.441 ± 0.978
1.801MetGlu: 1.801 ± 0.932
0.72MetPhe: 0.72 ± 0.373
1.081MetGly: 1.081 ± 0.559
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.081MetLys: 1.081 ± 1.007
2.522MetLeu: 2.522 ± 0.946
0.72MetMet: 0.72 ± 0.373
0.36MetAsn: 0.36 ± 0.186
1.441MetPro: 1.441 ± 0.747
0.36MetGln: 0.36 ± 0.547
2.522MetArg: 2.522 ± 1.304
0.72MetSer: 0.72 ± 0.705
0.72MetThr: 0.72 ± 0.373
0.72MetVal: 0.72 ± 0.474
0.36MetTrp: 0.36 ± 0.186
0.36MetTyr: 0.36 ± 0.186
0.0MetXaa: 0.0 ± 0.0
Asn
3.242AsnAla: 3.242 ± 1.252
1.801AsnCys: 1.801 ± 0.801
1.081AsnAsp: 1.081 ± 0.565
2.522AsnGlu: 2.522 ± 0.946
2.161AsnPhe: 2.161 ± 1.118
3.242AsnGly: 3.242 ± 1.209
1.081AsnHis: 1.081 ± 0.857
1.081AsnIle: 1.081 ± 0.559
1.441AsnLys: 1.441 ± 0.978
4.683AsnLeu: 4.683 ± 2.006
1.441AsnMet: 1.441 ± 0.533
2.522AsnAsn: 2.522 ± 1.947
1.801AsnPro: 1.801 ± 0.925
1.441AsnGln: 1.441 ± 0.948
2.161AsnArg: 2.161 ± 0.789
3.602AsnSer: 3.602 ± 1.053
2.882AsnThr: 2.882 ± 1.49
2.882AsnVal: 2.882 ± 1.125
0.36AsnTrp: 0.36 ± 0.186
1.441AsnTyr: 1.441 ± 0.658
0.0AsnXaa: 0.0 ± 0.0
Pro
3.963ProAla: 3.963 ± 2.209
1.081ProCys: 1.081 ± 0.559
1.441ProAsp: 1.441 ± 0.747
3.242ProGlu: 3.242 ± 1.016
1.441ProPhe: 1.441 ± 0.745
4.323ProGly: 4.323 ± 1.122
2.161ProHis: 2.161 ± 0.892
2.522ProIle: 2.522 ± 0.446
1.081ProLys: 1.081 ± 0.663
2.882ProLeu: 2.882 ± 0.867
0.0ProMet: 0.0 ± 0.0
2.161ProAsn: 2.161 ± 0.792
3.242ProPro: 3.242 ± 1.862
0.72ProGln: 0.72 ± 0.373
2.522ProArg: 2.522 ± 1.302
3.602ProSer: 3.602 ± 1.053
3.963ProThr: 3.963 ± 2.336
3.963ProVal: 3.963 ± 1.954
1.801ProTrp: 1.801 ± 1.392
1.801ProTyr: 1.801 ± 0.647
0.0ProXaa: 0.0 ± 0.0
Gln
2.161GlnAla: 2.161 ± 0.938
1.081GlnCys: 1.081 ± 0.565
0.72GlnAsp: 0.72 ± 0.373
1.081GlnGlu: 1.081 ± 1.007
1.081GlnPhe: 1.081 ± 0.663
3.602GlnGly: 3.602 ± 2.042
1.441GlnHis: 1.441 ± 0.747
2.161GlnIle: 2.161 ± 1.576
0.72GlnLys: 0.72 ± 0.373
3.242GlnLeu: 3.242 ± 0.625
1.441GlnMet: 1.441 ± 0.948
0.72GlnAsn: 0.72 ± 1.022
2.522GlnPro: 2.522 ± 1.046
1.441GlnGln: 1.441 ± 0.745
0.36GlnArg: 0.36 ± 0.547
2.882GlnSer: 2.882 ± 1.112
1.801GlnThr: 1.801 ± 0.559
1.081GlnVal: 1.081 ± 0.948
0.0GlnTrp: 0.0 ± 0.0
1.801GlnTyr: 1.801 ± 0.647
0.0GlnXaa: 0.0 ± 0.0
Arg
6.484ArgAla: 6.484 ± 1.903
1.081ArgCys: 1.081 ± 1.486
2.522ArgAsp: 2.522 ± 1.602
2.882ArgGlu: 2.882 ± 1.491
5.403ArgPhe: 5.403 ± 1.125
2.882ArgGly: 2.882 ± 0.632
1.081ArgHis: 1.081 ± 0.565
3.242ArgIle: 3.242 ± 0.971
3.242ArgLys: 3.242 ± 0.983
6.124ArgLeu: 6.124 ± 1.656
1.441ArgMet: 1.441 ± 0.745
3.963ArgAsn: 3.963 ± 2.423
3.242ArgPro: 3.242 ± 1.94
0.72ArgGln: 0.72 ± 0.773
5.764ArgArg: 5.764 ± 3.839
5.764ArgSer: 5.764 ± 2.202
1.801ArgThr: 1.801 ± 1.357
2.522ArgVal: 2.522 ± 0.888
1.801ArgTrp: 1.801 ± 0.801
3.602ArgTyr: 3.602 ± 0.791
0.0ArgXaa: 0.0 ± 0.0
Ser
5.403SerAla: 5.403 ± 1.481
2.522SerCys: 2.522 ± 1.305
3.602SerAsp: 3.602 ± 0.746
5.043SerGlu: 5.043 ± 3.21
2.522SerPhe: 2.522 ± 0.764
2.522SerGly: 2.522 ± 0.783
2.882SerHis: 2.882 ± 1.73
6.124SerIle: 6.124 ± 1.924
4.323SerLys: 4.323 ± 1.746
6.124SerLeu: 6.124 ± 1.258
1.801SerMet: 1.801 ± 0.431
2.522SerAsn: 2.522 ± 1.836
2.882SerPro: 2.882 ± 2.419
2.161SerGln: 2.161 ± 0.789
3.242SerArg: 3.242 ± 0.778
5.403SerSer: 5.403 ± 2.083
1.801SerThr: 1.801 ± 0.932
3.963SerVal: 3.963 ± 4.483
0.36SerTrp: 0.36 ± 0.186
1.801SerTyr: 1.801 ± 0.559
0.0SerXaa: 0.0 ± 0.0
Thr
3.242ThrAla: 3.242 ± 0.912
1.801ThrCys: 1.801 ± 0.731
2.522ThrAsp: 2.522 ± 0.764
3.602ThrGlu: 3.602 ± 1.332
5.403ThrPhe: 5.403 ± 0.979
4.323ThrGly: 4.323 ± 1.003
1.441ThrHis: 1.441 ± 0.745
4.323ThrIle: 4.323 ± 1.746
2.161ThrLys: 2.161 ± 0.892
5.764ThrLeu: 5.764 ± 1.947
1.441ThrMet: 1.441 ± 0.745
2.161ThrAsn: 2.161 ± 1.043
3.963ThrPro: 3.963 ± 0.933
0.36ThrGln: 0.36 ± 0.79
3.602ThrArg: 3.602 ± 1.714
2.882ThrSer: 2.882 ± 1.742
2.161ThrThr: 2.161 ± 0.899
3.242ThrVal: 3.242 ± 1.064
0.0ThrTrp: 0.0 ± 0.0
1.801ThrTyr: 1.801 ± 0.559
0.0ThrXaa: 0.0 ± 0.0
Val
5.043ValAla: 5.043 ± 1.149
3.242ValCys: 3.242 ± 1.062
2.161ValAsp: 2.161 ± 0.455
3.963ValGlu: 3.963 ± 1.408
1.441ValPhe: 1.441 ± 2.06
2.882ValGly: 2.882 ± 2.164
1.441ValHis: 1.441 ± 1.297
2.882ValIle: 2.882 ± 2.414
2.161ValLys: 2.161 ± 1.118
6.124ValLeu: 6.124 ± 1.342
0.36ValMet: 0.36 ± 0.186
1.441ValAsn: 1.441 ± 0.745
2.882ValPro: 2.882 ± 1.315
1.441ValGln: 1.441 ± 0.658
3.963ValArg: 3.963 ± 0.805
5.043ValSer: 5.043 ± 1.442
2.882ValThr: 2.882 ± 1.379
3.963ValVal: 3.963 ± 2.367
1.081ValTrp: 1.081 ± 0.857
2.882ValTyr: 2.882 ± 1.034
0.0ValXaa: 0.0 ± 0.0
Trp
1.441TrpAla: 1.441 ± 0.53
0.72TrpCys: 0.72 ± 0.373
0.36TrpAsp: 0.36 ± 0.186
0.0TrpGlu: 0.0 ± 0.0
0.72TrpPhe: 0.72 ± 0.373
0.72TrpGly: 0.72 ± 0.705
0.36TrpHis: 0.36 ± 0.186
0.72TrpIle: 0.72 ± 0.705
0.0TrpLys: 0.0 ± 0.0
1.801TrpLeu: 1.801 ± 0.801
0.36TrpMet: 0.36 ± 0.186
0.72TrpAsn: 0.72 ± 0.474
0.72TrpPro: 0.72 ± 0.705
0.36TrpGln: 0.36 ± 0.547
0.0TrpArg: 0.0 ± 0.0
0.36TrpSer: 0.36 ± 0.186
0.72TrpThr: 0.72 ± 0.773
0.72TrpVal: 0.72 ± 0.373
0.0TrpTrp: 0.0 ± 0.0
0.72TrpTyr: 0.72 ± 0.373
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.522TyrAla: 2.522 ± 0.975
1.081TyrCys: 1.081 ± 1.179
1.441TyrAsp: 1.441 ± 0.745
2.882TyrGlu: 2.882 ± 1.768
0.72TyrPhe: 0.72 ± 0.373
1.801TyrGly: 1.801 ± 0.647
0.0TyrHis: 0.0 ± 0.0
2.882TyrIle: 2.882 ± 0.907
3.242TyrLys: 3.242 ± 1.247
2.882TyrLeu: 2.882 ± 1.076
1.081TyrMet: 1.081 ± 0.559
2.522TyrAsn: 2.522 ± 0.987
2.522TyrPro: 2.522 ± 0.753
1.081TyrGln: 1.081 ± 0.559
2.161TyrArg: 2.161 ± 0.892
1.081TyrSer: 1.081 ± 0.565
3.963TyrThr: 3.963 ± 1.408
0.72TyrVal: 0.72 ± 0.474
0.36TyrTrp: 0.36 ± 0.186
1.441TyrTyr: 1.441 ± 0.53
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2777 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski