Amino acid dipepetide frequency for Bacteroidetes bacterium oral taxon 272 str. F0290

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.133AlaAla: 6.133 ± 0.108
1.063AlaCys: 1.063 ± 0.039
4.488AlaAsp: 4.488 ± 0.079
4.991AlaGlu: 4.991 ± 0.082
3.352AlaPhe: 3.352 ± 0.075
5.075AlaGly: 5.075 ± 0.102
1.434AlaHis: 1.434 ± 0.045
4.742AlaIle: 4.742 ± 0.085
4.381AlaLys: 4.381 ± 0.091
6.994AlaLeu: 6.994 ± 0.099
1.914AlaMet: 1.914 ± 0.054
3.171AlaAsn: 3.171 ± 0.068
2.292AlaPro: 2.292 ± 0.058
2.727AlaGln: 2.727 ± 0.06
3.407AlaArg: 3.407 ± 0.071
4.259AlaSer: 4.259 ± 0.066
3.836AlaThr: 3.836 ± 0.08
5.436AlaVal: 5.436 ± 0.099
0.876AlaTrp: 0.876 ± 0.034
3.224AlaTyr: 3.224 ± 0.06
0.0AlaXaa: 0.0 ± 0.0
Cys
0.771CysAla: 0.771 ± 0.034
0.212CysCys: 0.212 ± 0.019
0.608CysAsp: 0.608 ± 0.027
0.685CysGlu: 0.685 ± 0.033
0.614CysPhe: 0.614 ± 0.03
1.068CysGly: 1.068 ± 0.043
0.298CysHis: 0.298 ± 0.025
0.886CysIle: 0.886 ± 0.037
0.625CysLys: 0.625 ± 0.035
1.079CysLeu: 1.079 ± 0.037
0.31CysMet: 0.31 ± 0.021
0.535CysAsn: 0.535 ± 0.026
0.515CysPro: 0.515 ± 0.028
0.3CysGln: 0.3 ± 0.021
0.776CysArg: 0.776 ± 0.033
0.706CysSer: 0.706 ± 0.034
0.651CysThr: 0.651 ± 0.026
0.689CysVal: 0.689 ± 0.028
0.149CysTrp: 0.149 ± 0.015
0.492CysTyr: 0.492 ± 0.029
0.0CysXaa: 0.0 ± 0.0
Asp
4.089AspAla: 4.089 ± 0.076
0.598AspCys: 0.598 ± 0.028
2.772AspAsp: 2.772 ± 0.06
4.092AspGlu: 4.092 ± 0.083
3.108AspPhe: 3.108 ± 0.066
4.047AspGly: 4.047 ± 0.09
0.994AspHis: 0.994 ± 0.039
3.992AspIle: 3.992 ± 0.069
3.783AspLys: 3.783 ± 0.08
4.811AspLeu: 4.811 ± 0.086
1.655AspMet: 1.655 ± 0.048
2.31AspAsn: 2.31 ± 0.048
2.163AspPro: 2.163 ± 0.052
1.356AspGln: 1.356 ± 0.047
3.328AspArg: 3.328 ± 0.072
2.897AspSer: 2.897 ± 0.067
2.765AspThr: 2.765 ± 0.06
3.46AspVal: 3.46 ± 0.075
0.907AspTrp: 0.907 ± 0.037
3.025AspTyr: 3.025 ± 0.07
0.0AspXaa: 0.0 ± 0.0
Glu
5.133GluAla: 5.133 ± 0.093
0.608GluCys: 0.608 ± 0.029
3.08GluAsp: 3.08 ± 0.059
5.283GluGlu: 5.283 ± 0.103
2.281GluPhe: 2.281 ± 0.053
4.23GluGly: 4.23 ± 0.073
1.269GluHis: 1.269 ± 0.047
4.771GluIle: 4.771 ± 0.081
5.244GluLys: 5.244 ± 0.089
5.828GluLeu: 5.828 ± 0.101
1.992GluMet: 1.992 ± 0.057
3.223GluAsn: 3.223 ± 0.071
1.744GluPro: 1.744 ± 0.054
2.353GluGln: 2.353 ± 0.055
3.842GluArg: 3.842 ± 0.087
2.981GluSer: 2.981 ± 0.061
3.58GluThr: 3.58 ± 0.072
4.239GluVal: 4.239 ± 0.085
0.831GluTrp: 0.831 ± 0.034
2.386GluTyr: 2.386 ± 0.059
0.0GluXaa: 0.0 ± 0.0
Phe
3.131PheAla: 3.131 ± 0.067
0.661PheCys: 0.661 ± 0.029
2.881PheAsp: 2.881 ± 0.058
2.44PheGlu: 2.44 ± 0.057
2.242PhePhe: 2.242 ± 0.053
3.423PheGly: 3.423 ± 0.077
0.985PheHis: 0.985 ± 0.032
3.128PheIle: 3.128 ± 0.079
2.312PheLys: 2.312 ± 0.056
4.125PheLeu: 4.125 ± 0.082
1.238PheMet: 1.238 ± 0.04
2.159PheAsn: 2.159 ± 0.057
1.792PhePro: 1.792 ± 0.046
1.237PheGln: 1.237 ± 0.039
2.451PheArg: 2.451 ± 0.055
3.34PheSer: 3.34 ± 0.074
2.573PheThr: 2.573 ± 0.065
3.113PheVal: 3.113 ± 0.069
0.521PheTrp: 0.521 ± 0.03
1.934PheTyr: 1.934 ± 0.056
0.0PheXaa: 0.0 ± 0.0
Gly
4.567GlyAla: 4.567 ± 0.087
0.878GlyCys: 0.878 ± 0.041
3.479GlyAsp: 3.479 ± 0.073
4.116GlyGlu: 4.116 ± 0.077
3.184GlyPhe: 3.184 ± 0.061
4.842GlyGly: 4.842 ± 0.103
1.363GlyHis: 1.363 ± 0.041
5.543GlyIle: 5.543 ± 0.098
5.524GlyLys: 5.524 ± 0.11
5.765GlyLeu: 5.765 ± 0.091
2.325GlyMet: 2.325 ± 0.058
3.361GlyAsn: 3.361 ± 0.078
1.394GlyPro: 1.394 ± 0.039
2.044GlyGln: 2.044 ± 0.056
3.34GlyArg: 3.34 ± 0.076
3.924GlySer: 3.924 ± 0.086
4.295GlyThr: 4.295 ± 0.09
4.483GlyVal: 4.483 ± 0.086
1.043GlyTrp: 1.043 ± 0.042
3.396GlyTyr: 3.396 ± 0.078
0.0GlyXaa: 0.0 ± 0.0
His
1.58HisAla: 1.58 ± 0.05
0.328HisCys: 0.328 ± 0.022
1.019HisAsp: 1.019 ± 0.036
1.02HisGlu: 1.02 ± 0.037
1.179HisPhe: 1.179 ± 0.039
1.275HisGly: 1.275 ± 0.038
0.537HisHis: 0.537 ± 0.026
1.741HisIle: 1.741 ± 0.049
1.005HisLys: 1.005 ± 0.042
1.955HisLeu: 1.955 ± 0.056
0.374HisMet: 0.374 ± 0.023
0.831HisAsn: 0.831 ± 0.03
1.193HisPro: 1.193 ± 0.045
0.615HisGln: 0.615 ± 0.032
1.304HisArg: 1.304 ± 0.049
1.102HisSer: 1.102 ± 0.038
1.161HisThr: 1.161 ± 0.037
1.226HisVal: 1.226 ± 0.041
0.284HisTrp: 0.284 ± 0.021
0.974HisTyr: 0.974 ± 0.035
0.0HisXaa: 0.0 ± 0.0
Ile
5.707IleAla: 5.707 ± 0.108
0.931IleCys: 0.931 ± 0.044
4.703IleAsp: 4.703 ± 0.083
4.348IleGlu: 4.348 ± 0.083
2.769IlePhe: 2.769 ± 0.07
5.066IleGly: 5.066 ± 0.096
1.458IleHis: 1.458 ± 0.041
3.817IleIle: 3.817 ± 0.084
3.665IleLys: 3.665 ± 0.083
5.739IleLeu: 5.739 ± 0.109
1.496IleMet: 1.496 ± 0.047
2.936IleAsn: 2.936 ± 0.071
3.375IlePro: 3.375 ± 0.059
2.006IleGln: 2.006 ± 0.056
4.268IleArg: 4.268 ± 0.077
4.193IleSer: 4.193 ± 0.084
3.594IleThr: 3.594 ± 0.07
4.721IleVal: 4.721 ± 0.089
0.658IleTrp: 0.658 ± 0.029
2.703IleTyr: 2.703 ± 0.068
0.0IleXaa: 0.0 ± 0.0
Lys
5.134LysAla: 5.134 ± 0.088
0.507LysCys: 0.507 ± 0.026
3.743LysAsp: 3.743 ± 0.076
5.412LysGlu: 5.412 ± 0.096
2.144LysPhe: 2.144 ± 0.056
4.494LysGly: 4.494 ± 0.079
1.374LysHis: 1.374 ± 0.044
4.24LysIle: 4.24 ± 0.079
4.736LysLys: 4.736 ± 0.093
5.197LysLeu: 5.197 ± 0.082
2.033LysMet: 2.033 ± 0.053
3.419LysAsn: 3.419 ± 0.074
2.225LysPro: 2.225 ± 0.05
2.296LysGln: 2.296 ± 0.058
3.664LysArg: 3.664 ± 0.081
3.14LysSer: 3.14 ± 0.07
3.816LysThr: 3.816 ± 0.069
4.151LysVal: 4.151 ± 0.09
0.749LysTrp: 0.749 ± 0.037
2.739LysTyr: 2.739 ± 0.057
0.0LysXaa: 0.0 ± 0.0
Leu
6.184LeuAla: 6.184 ± 0.099
1.244LeuCys: 1.244 ± 0.041
4.543LeuAsp: 4.543 ± 0.075
4.705LeuGlu: 4.705 ± 0.085
4.754LeuPhe: 4.754 ± 0.101
5.37LeuGly: 5.37 ± 0.082
2.006LeuHis: 2.006 ± 0.057
5.954LeuIle: 5.954 ± 0.106
6.391LeuLys: 6.391 ± 0.096
8.853LeuLeu: 8.853 ± 0.15
2.443LeuMet: 2.443 ± 0.065
4.57LeuAsn: 4.57 ± 0.087
4.051LeuPro: 4.051 ± 0.065
3.246LeuGln: 3.246 ± 0.065
4.634LeuArg: 4.634 ± 0.08
6.568LeuSer: 6.568 ± 0.109
5.473LeuThr: 5.473 ± 0.084
4.78LeuVal: 4.78 ± 0.086
1.082LeuTrp: 1.082 ± 0.041
3.614LeuTyr: 3.614 ± 0.076
0.0LeuXaa: 0.0 ± 0.0
Met
2.029MetAla: 2.029 ± 0.058
0.19MetCys: 0.19 ± 0.014
1.548MetAsp: 1.548 ± 0.048
1.908MetGlu: 1.908 ± 0.049
0.937MetPhe: 0.937 ± 0.038
1.84MetGly: 1.84 ± 0.052
0.525MetHis: 0.525 ± 0.03
1.795MetIle: 1.795 ± 0.055
2.678MetLys: 2.678 ± 0.06
2.502MetLeu: 2.502 ± 0.062
0.818MetMet: 0.818 ± 0.031
1.737MetAsn: 1.737 ± 0.042
1.198MetPro: 1.198 ± 0.041
0.931MetGln: 0.931 ± 0.032
1.453MetArg: 1.453 ± 0.04
1.407MetSer: 1.407 ± 0.041
1.496MetThr: 1.496 ± 0.047
1.497MetVal: 1.497 ± 0.044
0.213MetTrp: 0.213 ± 0.019
0.788MetTyr: 0.788 ± 0.037
0.0MetXaa: 0.0 ± 0.0
Asn
3.423AsnAla: 3.423 ± 0.076
0.43AsnCys: 0.43 ± 0.025
2.544AsnAsp: 2.544 ± 0.052
2.918AsnGlu: 2.918 ± 0.07
2.107AsnPhe: 2.107 ± 0.05
3.7AsnGly: 3.7 ± 0.097
0.974AsnHis: 0.974 ± 0.035
3.224AsnIle: 3.224 ± 0.077
2.805AsnLys: 2.805 ± 0.071
4.076AsnLeu: 4.076 ± 0.077
1.236AsnMet: 1.236 ± 0.043
2.156AsnAsn: 2.156 ± 0.063
2.416AsnPro: 2.416 ± 0.057
1.39AsnGln: 1.39 ± 0.048
2.834AsnArg: 2.834 ± 0.068
2.427AsnSer: 2.427 ± 0.055
2.485AsnThr: 2.485 ± 0.068
3.074AsnVal: 3.074 ± 0.071
0.663AsnTrp: 0.663 ± 0.033
2.297AsnTyr: 2.297 ± 0.061
0.0AsnXaa: 0.0 ± 0.0
Pro
2.893ProAla: 2.893 ± 0.067
0.359ProCys: 0.359 ± 0.024
2.619ProAsp: 2.619 ± 0.063
3.19ProGlu: 3.19 ± 0.061
1.969ProPhe: 1.969 ± 0.049
2.304ProGly: 2.304 ± 0.068
0.89ProHis: 0.89 ± 0.037
2.396ProIle: 2.396 ± 0.051
2.038ProLys: 2.038 ± 0.052
3.258ProLeu: 3.258 ± 0.069
0.986ProMet: 0.986 ± 0.033
1.721ProAsn: 1.721 ± 0.049
1.052ProPro: 1.052 ± 0.041
1.414ProGln: 1.414 ± 0.04
1.476ProArg: 1.476 ± 0.048
2.357ProSer: 2.357 ± 0.062
2.172ProThr: 2.172 ± 0.061
2.964ProVal: 2.964 ± 0.072
0.466ProTrp: 0.466 ± 0.029
1.828ProTyr: 1.828 ± 0.049
0.0ProXaa: 0.0 ± 0.0
Gln
2.528GlnAla: 2.528 ± 0.059
0.316GlnCys: 0.316 ± 0.021
1.521GlnAsp: 1.521 ± 0.044
2.205GlnGlu: 2.205 ± 0.059
1.217GlnPhe: 1.217 ± 0.042
2.04GlnGly: 2.04 ± 0.057
0.73GlnHis: 0.73 ± 0.035
2.407GlnIle: 2.407 ± 0.058
2.124GlnLys: 2.124 ± 0.06
3.2GlnLeu: 3.2 ± 0.074
0.954GlnMet: 0.954 ± 0.036
1.496GlnAsn: 1.496 ± 0.053
1.161GlnPro: 1.161 ± 0.038
1.405GlnGln: 1.405 ± 0.049
1.77GlnArg: 1.77 ± 0.05
1.697GlnSer: 1.697 ± 0.054
2.071GlnThr: 2.071 ± 0.057
2.028GlnVal: 2.028 ± 0.056
0.419GlnTrp: 0.419 ± 0.028
1.308GlnTyr: 1.308 ± 0.047
0.0GlnXaa: 0.0 ± 0.0
Arg
3.231ArgAla: 3.231 ± 0.067
0.579ArgCys: 0.579 ± 0.029
2.45ArgAsp: 2.45 ± 0.059
3.546ArgGlu: 3.546 ± 0.079
2.667ArgPhe: 2.667 ± 0.066
2.845ArgGly: 2.845 ± 0.059
1.22ArgHis: 1.22 ± 0.038
4.374ArgIle: 4.374 ± 0.075
3.994ArgLys: 3.994 ± 0.079
5.282ArgLeu: 5.282 ± 0.108
1.786ArgMet: 1.786 ± 0.052
2.648ArgAsn: 2.648 ± 0.063
1.903ArgPro: 1.903 ± 0.055
2.18ArgGln: 2.18 ± 0.055
3.206ArgArg: 3.206 ± 0.088
2.86ArgSer: 2.86 ± 0.073
2.951ArgThr: 2.951 ± 0.056
2.715ArgVal: 2.715 ± 0.073
0.76ArgTrp: 0.76 ± 0.04
2.591ArgTyr: 2.591 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
4.137SerAla: 4.137 ± 0.079
0.815SerCys: 0.815 ± 0.029
3.191SerAsp: 3.191 ± 0.058
3.301SerGlu: 3.301 ± 0.078
3.074SerPhe: 3.074 ± 0.067
4.448SerGly: 4.448 ± 0.086
1.136SerHis: 1.136 ± 0.034
3.968SerIle: 3.968 ± 0.076
3.325SerLys: 3.325 ± 0.069
5.633SerLeu: 5.633 ± 0.09
1.585SerMet: 1.585 ± 0.04
2.458SerAsn: 2.458 ± 0.061
2.213SerPro: 2.213 ± 0.058
1.616SerGln: 1.616 ± 0.043
2.743SerArg: 2.743 ± 0.062
3.617SerSer: 3.617 ± 0.084
3.022SerThr: 3.022 ± 0.069
4.243SerVal: 4.243 ± 0.078
0.791SerTrp: 0.791 ± 0.042
2.67SerTyr: 2.67 ± 0.079
0.0SerXaa: 0.0 ± 0.0
Thr
4.415ThrAla: 4.415 ± 0.072
0.58ThrCys: 0.58 ± 0.03
3.664ThrAsp: 3.664 ± 0.075
3.381ThrGlu: 3.381 ± 0.072
2.672ThrPhe: 2.672 ± 0.057
4.314ThrGly: 4.314 ± 0.079
1.091ThrHis: 1.091 ± 0.038
3.564ThrIle: 3.564 ± 0.067
2.985ThrLys: 2.985 ± 0.068
5.268ThrLeu: 5.268 ± 0.079
1.253ThrMet: 1.253 ± 0.043
2.438ThrAsn: 2.438 ± 0.064
2.616ThrPro: 2.616 ± 0.062
1.628ThrGln: 1.628 ± 0.047
2.3ThrArg: 2.3 ± 0.057
3.145ThrSer: 3.145 ± 0.065
2.975ThrThr: 2.975 ± 0.073
4.403ThrVal: 4.403 ± 0.087
0.667ThrTrp: 0.667 ± 0.031
2.419ThrTyr: 2.419 ± 0.056
0.0ThrXaa: 0.0 ± 0.0
Val
4.636ValAla: 4.636 ± 0.094
1.001ValCys: 1.001 ± 0.041
4.0ValAsp: 4.0 ± 0.074
4.014ValGlu: 4.014 ± 0.081
2.79ValPhe: 2.79 ± 0.069
4.44ValGly: 4.44 ± 0.086
1.169ValHis: 1.169 ± 0.034
4.167ValIle: 4.167 ± 0.088
4.219ValLys: 4.219 ± 0.077
5.693ValLeu: 5.693 ± 0.096
1.636ValMet: 1.636 ± 0.05
3.082ValAsn: 3.082 ± 0.058
2.702ValPro: 2.702 ± 0.066
1.934ValGln: 1.934 ± 0.05
3.543ValArg: 3.543 ± 0.072
4.353ValSer: 4.353 ± 0.08
3.708ValThr: 3.708 ± 0.083
4.293ValVal: 4.293 ± 0.093
0.717ValTrp: 0.717 ± 0.033
2.656ValTyr: 2.656 ± 0.056
0.0ValXaa: 0.0 ± 0.0
Trp
0.768TrpAla: 0.768 ± 0.034
0.162TrpCys: 0.162 ± 0.014
0.698TrpAsp: 0.698 ± 0.036
0.771TrpGlu: 0.771 ± 0.03
0.543TrpPhe: 0.543 ± 0.03
0.953TrpGly: 0.953 ± 0.036
0.312TrpHis: 0.312 ± 0.02
0.887TrpIle: 0.887 ± 0.038
0.958TrpLys: 0.958 ± 0.037
1.061TrpLeu: 1.061 ± 0.041
0.446TrpMet: 0.446 ± 0.021
0.834TrpAsn: 0.834 ± 0.032
0.33TrpPro: 0.33 ± 0.02
0.469TrpGln: 0.469 ± 0.027
0.611TrpArg: 0.611 ± 0.03
0.655TrpSer: 0.655 ± 0.03
0.7TrpThr: 0.7 ± 0.031
0.708TrpVal: 0.708 ± 0.032
0.19TrpTrp: 0.19 ± 0.016
0.535TrpTyr: 0.535 ± 0.03
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.308TyrAla: 3.308 ± 0.069
0.504TyrCys: 0.504 ± 0.026
2.603TyrAsp: 2.603 ± 0.065
2.573TyrGlu: 2.573 ± 0.054
2.084TyrPhe: 2.084 ± 0.06
3.093TyrGly: 3.093 ± 0.073
0.937TyrHis: 0.937 ± 0.036
2.557TyrIle: 2.557 ± 0.056
2.419TyrLys: 2.419 ± 0.063
4.147TyrLeu: 4.147 ± 0.087
1.008TyrMet: 1.008 ± 0.041
2.095TyrAsn: 2.095 ± 0.062
2.021TyrPro: 2.021 ± 0.046
1.447TyrGln: 1.447 ± 0.047
2.837TyrArg: 2.837 ± 0.071
2.359TyrSer: 2.359 ± 0.061
2.455TyrThr: 2.455 ± 0.06
2.53TyrVal: 2.53 ± 0.057
0.603TyrTrp: 0.603 ± 0.033
2.001TyrTyr: 2.001 ± 0.056
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2103 proteins (746167 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski