Amino acid dipepetide frequency for Beihai weivirus-like virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.377AlaAla: 19.377 ± 0.668
2.527AlaCys: 2.527 ± 0.256
7.582AlaAsp: 7.582 ± 0.811
6.74AlaGlu: 6.74 ± 0.37
0.842AlaPhe: 0.842 ± 0.441
9.267AlaGly: 9.267 ± 3.272
0.842AlaHis: 0.842 ± 0.441
2.527AlaIle: 2.527 ± 1.323
5.055AlaLys: 5.055 ± 0.512
11.794AlaLeu: 11.794 ± 1.721
4.212AlaMet: 4.212 ± 2.532
4.212AlaAsn: 4.212 ± 0.953
5.055AlaPro: 5.055 ± 2.091
5.055AlaGln: 5.055 ± 0.512
7.582AlaArg: 7.582 ± 0.768
7.582AlaSer: 7.582 ± 2.39
4.212AlaThr: 4.212 ± 4.111
9.267AlaVal: 9.267 ± 1.693
2.527AlaTrp: 2.527 ± 1.323
1.685AlaTyr: 1.685 ± 0.882
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.685CysCys: 1.685 ± 0.882
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.685CysGly: 1.685 ± 0.697
0.842CysHis: 0.842 ± 0.441
1.685CysIle: 1.685 ± 0.697
0.842CysLys: 0.842 ± 0.441
0.0CysLeu: 0.0 ± 0.0
0.842CysMet: 0.842 ± 0.441
0.0CysAsn: 0.0 ± 0.0
1.685CysPro: 1.685 ± 0.882
0.842CysGln: 0.842 ± 0.441
1.685CysArg: 1.685 ± 0.697
5.055CysSer: 5.055 ± 1.067
1.685CysThr: 1.685 ± 0.882
1.685CysVal: 1.685 ± 0.882
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.055AspAla: 5.055 ± 1.067
0.0AspCys: 0.0 ± 0.0
4.212AspAsp: 4.212 ± 0.626
1.685AspGlu: 1.685 ± 0.882
1.685AspPhe: 1.685 ± 0.882
3.37AspGly: 3.37 ± 0.185
0.0AspHis: 0.0 ± 0.0
0.0AspIle: 0.0 ± 0.0
5.897AspLys: 5.897 ± 3.087
5.055AspLeu: 5.055 ± 2.091
1.685AspMet: 1.685 ± 0.697
0.0AspAsn: 0.0 ± 0.0
3.37AspPro: 3.37 ± 1.394
0.842AspGln: 0.842 ± 0.441
4.212AspArg: 4.212 ± 0.626
3.37AspSer: 3.37 ± 0.185
2.527AspThr: 2.527 ± 1.835
5.055AspVal: 5.055 ± 0.512
0.0AspTrp: 0.0 ± 0.0
4.212AspTyr: 4.212 ± 0.953
0.0AspXaa: 0.0 ± 0.0
Glu
8.425GluAla: 8.425 ± 4.41
0.0GluCys: 0.0 ± 0.0
5.055GluAsp: 5.055 ± 0.512
8.425GluGlu: 8.425 ± 2.831
4.212GluPhe: 4.212 ± 0.626
5.897GluGly: 5.897 ± 3.087
1.685GluHis: 1.685 ± 0.882
2.527GluIle: 2.527 ± 1.323
2.527GluLys: 2.527 ± 1.323
6.74GluLeu: 6.74 ± 0.37
1.685GluMet: 1.685 ± 0.697
1.685GluAsn: 1.685 ± 0.882
0.0GluPro: 0.0 ± 0.0
2.527GluGln: 2.527 ± 1.323
0.842GluArg: 0.842 ± 0.441
3.37GluSer: 3.37 ± 1.764
2.527GluThr: 2.527 ± 0.256
2.527GluVal: 2.527 ± 0.256
0.842GluTrp: 0.842 ± 1.138
0.842GluTyr: 0.842 ± 1.138
0.0GluXaa: 0.0 ± 0.0
Phe
4.212PheAla: 4.212 ± 0.626
1.685PheCys: 1.685 ± 0.882
3.37PheAsp: 3.37 ± 1.394
2.527PheGlu: 2.527 ± 1.323
0.0PhePhe: 0.0 ± 0.0
0.842PheGly: 0.842 ± 1.138
0.842PheHis: 0.842 ± 0.441
2.527PheIle: 2.527 ± 1.835
2.527PheLys: 2.527 ± 1.323
3.37PheLeu: 3.37 ± 0.185
0.842PheMet: 0.842 ± 1.138
1.685PheAsn: 1.685 ± 0.882
0.842PhePro: 0.842 ± 0.441
0.0PheGln: 0.0 ± 0.0
1.685PheArg: 1.685 ± 0.882
1.685PheSer: 1.685 ± 0.697
2.527PheThr: 2.527 ± 1.835
4.212PheVal: 4.212 ± 0.953
0.842PheTrp: 0.842 ± 0.441
0.842PheTyr: 0.842 ± 0.441
0.0PheXaa: 0.0 ± 0.0
Gly
5.897GlyAla: 5.897 ± 0.071
2.527GlyCys: 2.527 ± 1.323
4.212GlyAsp: 4.212 ± 2.205
0.842GlyGlu: 0.842 ± 0.441
0.842GlyPhe: 0.842 ± 0.441
5.055GlyGly: 5.055 ± 5.249
3.37GlyHis: 3.37 ± 0.185
2.527GlyIle: 2.527 ± 0.256
3.37GlyLys: 3.37 ± 0.185
5.055GlyLeu: 5.055 ± 1.067
2.527GlyMet: 2.527 ± 0.256
4.212GlyAsn: 4.212 ± 0.953
4.212GlyPro: 4.212 ± 0.626
2.527GlyGln: 2.527 ± 1.323
2.527GlyArg: 2.527 ± 0.256
4.212GlySer: 4.212 ± 0.626
4.212GlyThr: 4.212 ± 0.953
7.582GlyVal: 7.582 ± 0.768
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.842HisAla: 0.842 ± 1.138
0.0HisCys: 0.0 ± 0.0
2.527HisAsp: 2.527 ± 0.256
1.685HisGlu: 1.685 ± 0.882
2.527HisPhe: 2.527 ± 0.256
2.527HisGly: 2.527 ± 0.256
1.685HisHis: 1.685 ± 0.697
0.842HisIle: 0.842 ± 0.441
0.0HisLys: 0.0 ± 0.0
0.842HisLeu: 0.842 ± 0.441
1.685HisMet: 1.685 ± 0.882
0.842HisAsn: 0.842 ± 1.138
0.842HisPro: 0.842 ± 0.441
0.0HisGln: 0.0 ± 0.0
0.842HisArg: 0.842 ± 0.441
0.842HisSer: 0.842 ± 0.441
0.842HisThr: 0.842 ± 1.138
1.685HisVal: 1.685 ± 0.882
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.37IleAla: 3.37 ± 1.764
0.0IleCys: 0.0 ± 0.0
0.842IleAsp: 0.842 ± 0.441
3.37IleGlu: 3.37 ± 0.185
2.527IlePhe: 2.527 ± 0.256
0.842IleGly: 0.842 ± 1.138
0.0IleHis: 0.0 ± 0.0
1.685IleIle: 1.685 ± 0.697
4.212IleLys: 4.212 ± 0.626
5.055IleLeu: 5.055 ± 2.646
0.842IleMet: 0.842 ± 0.963
0.842IleAsn: 0.842 ± 0.441
0.842IlePro: 0.842 ± 1.138
1.685IleGln: 1.685 ± 0.882
1.685IleArg: 1.685 ± 0.697
3.37IleSer: 3.37 ± 1.394
5.055IleThr: 5.055 ± 0.512
1.685IleVal: 1.685 ± 0.882
0.0IleTrp: 0.0 ± 0.0
0.842IleTyr: 0.842 ± 0.441
0.0IleXaa: 0.0 ± 0.0
Lys
5.897LysAla: 5.897 ± 1.508
1.685LysCys: 1.685 ± 0.697
2.527LysAsp: 2.527 ± 1.323
2.527LysGlu: 2.527 ± 1.323
2.527LysPhe: 2.527 ± 1.323
2.527LysGly: 2.527 ± 1.323
0.842LysHis: 0.842 ± 0.441
1.685LysIle: 1.685 ± 0.882
8.425LysLys: 8.425 ± 2.831
5.897LysLeu: 5.897 ± 0.071
0.0LysMet: 0.0 ± 0.0
0.0LysAsn: 0.0 ± 0.0
5.055LysPro: 5.055 ± 0.512
0.842LysGln: 0.842 ± 0.441
2.527LysArg: 2.527 ± 0.256
5.055LysSer: 5.055 ± 2.091
6.74LysThr: 6.74 ± 1.949
4.212LysVal: 4.212 ± 2.205
1.685LysTrp: 1.685 ± 0.882
2.527LysTyr: 2.527 ± 1.323
0.0LysXaa: 0.0 ± 0.0
Leu
14.322LeuAla: 14.322 ± 3.557
1.685LeuCys: 1.685 ± 0.882
3.37LeuAsp: 3.37 ± 1.394
5.897LeuGlu: 5.897 ± 1.508
1.685LeuPhe: 1.685 ± 0.882
7.582LeuGly: 7.582 ± 2.39
0.0LeuHis: 0.0 ± 0.0
2.527LeuIle: 2.527 ± 0.256
5.055LeuLys: 5.055 ± 1.067
5.897LeuLeu: 5.897 ± 0.071
0.842LeuMet: 0.842 ± 0.648
1.685LeuAsn: 1.685 ± 0.882
2.527LeuPro: 2.527 ± 0.256
0.842LeuGln: 0.842 ± 0.441
8.425LeuArg: 8.425 ± 1.906
3.37LeuSer: 3.37 ± 0.185
5.055LeuThr: 5.055 ± 2.091
1.685LeuVal: 1.685 ± 0.882
1.685LeuTrp: 1.685 ± 0.697
0.842LeuTyr: 0.842 ± 0.441
0.0LeuXaa: 0.0 ± 0.0
Met
1.685MetAla: 1.685 ± 2.276
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
3.37MetGlu: 3.37 ± 0.185
1.685MetPhe: 1.685 ± 2.276
4.212MetGly: 4.212 ± 2.532
0.842MetHis: 0.842 ± 0.441
0.842MetIle: 0.842 ± 0.441
1.685MetLys: 1.685 ± 0.882
0.842MetLeu: 0.842 ± 0.441
0.0MetMet: 0.0 ± 0.0
0.842MetAsn: 0.842 ± 1.138
1.685MetPro: 1.685 ± 0.697
0.0MetGln: 0.0 ± 0.0
2.527MetArg: 2.527 ± 0.256
3.37MetSer: 3.37 ± 1.394
0.0MetThr: 0.0 ± 0.0
2.527MetVal: 2.527 ± 1.323
1.685MetTrp: 1.685 ± 0.882
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.055AsnAla: 5.055 ± 0.512
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.842AsnGlu: 0.842 ± 0.441
2.527AsnPhe: 2.527 ± 1.835
2.527AsnGly: 2.527 ± 0.256
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.842AsnLys: 0.842 ± 0.441
0.0AsnLeu: 0.0 ± 0.0
0.842AsnMet: 0.842 ± 0.441
1.685AsnAsn: 1.685 ± 2.276
3.37AsnPro: 3.37 ± 1.394
0.842AsnGln: 0.842 ± 1.138
0.842AsnArg: 0.842 ± 0.441
3.37AsnSer: 3.37 ± 1.394
0.0AsnThr: 0.0 ± 0.0
1.685AsnVal: 1.685 ± 0.882
1.685AsnTrp: 1.685 ± 0.697
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.055ProAla: 5.055 ± 2.091
1.685ProCys: 1.685 ± 0.882
3.37ProAsp: 3.37 ± 0.185
4.212ProGlu: 4.212 ± 2.205
1.685ProPhe: 1.685 ± 2.276
0.842ProGly: 0.842 ± 1.138
0.0ProHis: 0.0 ± 0.0
2.527ProIle: 2.527 ± 1.835
3.37ProLys: 3.37 ± 1.764
2.527ProLeu: 2.527 ± 1.835
0.0ProMet: 0.0 ± 0.0
2.527ProAsn: 2.527 ± 1.323
2.527ProPro: 2.527 ± 1.323
3.37ProGln: 3.37 ± 0.185
5.055ProArg: 5.055 ± 3.67
4.212ProSer: 4.212 ± 0.626
3.37ProThr: 3.37 ± 1.394
1.685ProVal: 1.685 ± 2.276
0.842ProTrp: 0.842 ± 0.441
0.842ProTyr: 0.842 ± 1.138
0.0ProXaa: 0.0 ± 0.0
Gln
0.842GlnAla: 0.842 ± 1.138
0.842GlnCys: 0.842 ± 0.441
0.842GlnAsp: 0.842 ± 0.441
2.527GlnGlu: 2.527 ± 1.323
1.685GlnPhe: 1.685 ± 0.697
0.842GlnGly: 0.842 ± 1.138
1.685GlnHis: 1.685 ± 0.882
1.685GlnIle: 1.685 ± 0.882
0.842GlnLys: 0.842 ± 0.441
0.0GlnLeu: 0.0 ± 0.0
0.842GlnMet: 0.842 ± 0.441
0.842GlnAsn: 0.842 ± 1.138
0.842GlnPro: 0.842 ± 0.441
0.842GlnGln: 0.842 ± 1.138
0.0GlnArg: 0.0 ± 0.0
0.842GlnSer: 0.842 ± 0.441
4.212GlnThr: 4.212 ± 0.953
5.055GlnVal: 5.055 ± 1.067
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
9.267ArgAla: 9.267 ± 1.465
0.0ArgCys: 0.0 ± 0.0
3.37ArgAsp: 3.37 ± 2.973
1.685ArgGlu: 1.685 ± 0.697
4.212ArgPhe: 4.212 ± 0.953
4.212ArgGly: 4.212 ± 0.626
0.0ArgHis: 0.0 ± 0.0
1.685ArgIle: 1.685 ± 0.882
2.527ArgLys: 2.527 ± 1.323
5.055ArgLeu: 5.055 ± 2.091
1.685ArgMet: 1.685 ± 0.882
1.685ArgAsn: 1.685 ± 2.276
0.842ArgPro: 0.842 ± 1.138
0.842ArgGln: 0.842 ± 0.441
4.212ArgArg: 4.212 ± 2.532
4.212ArgSer: 4.212 ± 2.205
5.897ArgThr: 5.897 ± 0.071
5.055ArgVal: 5.055 ± 2.091
3.37ArgTrp: 3.37 ± 1.764
1.685ArgTyr: 1.685 ± 0.882
0.0ArgXaa: 0.0 ± 0.0
Ser
7.582SerAla: 7.582 ± 0.811
0.842SerCys: 0.842 ± 0.441
3.37SerAsp: 3.37 ± 1.394
4.212SerGlu: 4.212 ± 0.626
0.0SerPhe: 0.0 ± 0.0
3.37SerGly: 3.37 ± 1.764
4.212SerHis: 4.212 ± 2.532
4.212SerIle: 4.212 ± 2.205
5.897SerLys: 5.897 ± 1.508
3.37SerLeu: 3.37 ± 0.185
1.685SerMet: 1.685 ± 0.697
0.0SerAsn: 0.0 ± 0.0
2.527SerPro: 2.527 ± 0.256
0.0SerGln: 0.0 ± 0.0
3.37SerArg: 3.37 ± 0.185
7.582SerSer: 7.582 ± 3.926
5.897SerThr: 5.897 ± 0.071
10.11SerVal: 10.11 ± 0.555
4.212SerTrp: 4.212 ± 0.626
0.842SerTyr: 0.842 ± 1.138
0.0SerXaa: 0.0 ± 0.0
Thr
9.267ThrAla: 9.267 ± 0.114
0.842ThrCys: 0.842 ± 0.441
1.685ThrAsp: 1.685 ± 0.882
3.37ThrGlu: 3.37 ± 0.185
4.212ThrPhe: 4.212 ± 2.205
3.37ThrGly: 3.37 ± 0.185
0.842ThrHis: 0.842 ± 1.138
5.055ThrIle: 5.055 ± 0.512
2.527ThrLys: 2.527 ± 1.835
5.055ThrLeu: 5.055 ± 2.091
4.212ThrMet: 4.212 ± 0.626
0.842ThrAsn: 0.842 ± 0.441
2.527ThrPro: 2.527 ± 3.414
0.0ThrGln: 0.0 ± 0.0
1.685ThrArg: 1.685 ± 2.276
4.212ThrSer: 4.212 ± 0.626
3.37ThrThr: 3.37 ± 1.394
3.37ThrVal: 3.37 ± 2.973
4.212ThrTrp: 4.212 ± 0.953
2.527ThrTyr: 2.527 ± 0.256
0.0ThrXaa: 0.0 ± 0.0
Val
7.582ValAla: 7.582 ± 0.768
3.37ValCys: 3.37 ± 0.185
0.842ValAsp: 0.842 ± 0.441
5.897ValGlu: 5.897 ± 0.071
1.685ValPhe: 1.685 ± 0.882
5.055ValGly: 5.055 ± 1.067
1.685ValHis: 1.685 ± 0.882
3.37ValIle: 3.37 ± 1.394
5.055ValLys: 5.055 ± 2.091
5.897ValLeu: 5.897 ± 3.087
2.527ValMet: 2.527 ± 1.835
1.685ValAsn: 1.685 ± 0.697
8.425ValPro: 8.425 ± 1.252
3.37ValGln: 3.37 ± 2.973
5.897ValArg: 5.897 ± 1.508
4.212ValSer: 4.212 ± 2.205
2.527ValThr: 2.527 ± 1.323
2.527ValVal: 2.527 ± 1.323
0.842ValTrp: 0.842 ± 1.138
1.685ValTyr: 1.685 ± 0.882
0.0ValXaa: 0.0 ± 0.0
Trp
2.527TrpAla: 2.527 ± 1.323
0.842TrpCys: 0.842 ± 1.138
3.37TrpAsp: 3.37 ± 0.185
0.842TrpGlu: 0.842 ± 0.441
0.842TrpPhe: 0.842 ± 0.441
0.0TrpGly: 0.0 ± 0.0
0.842TrpHis: 0.842 ± 1.138
0.842TrpIle: 0.842 ± 0.441
1.685TrpLys: 1.685 ± 0.882
1.685TrpLeu: 1.685 ± 0.697
0.0TrpMet: 0.0 ± 0.0
0.842TrpAsn: 0.842 ± 1.138
0.0TrpPro: 0.0 ± 0.0
0.842TrpGln: 0.842 ± 0.441
3.37TrpArg: 3.37 ± 0.185
1.685TrpSer: 1.685 ± 0.697
0.842TrpThr: 0.842 ± 0.441
2.527TrpVal: 2.527 ± 1.323
0.842TrpTrp: 0.842 ± 0.441
0.842TrpTyr: 0.842 ± 0.441
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.685TyrAla: 1.685 ± 0.882
0.0TyrCys: 0.0 ± 0.0
1.685TyrAsp: 1.685 ± 0.882
1.685TyrGlu: 1.685 ± 0.882
1.685TyrPhe: 1.685 ± 0.697
1.685TyrGly: 1.685 ± 0.697
0.842TyrHis: 0.842 ± 0.441
0.842TyrIle: 0.842 ± 0.441
0.842TyrLys: 0.842 ± 0.441
0.842TyrLeu: 0.842 ± 0.441
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.527TyrPro: 2.527 ± 1.835
0.0TyrGln: 0.0 ± 0.0
2.527TyrArg: 2.527 ± 1.323
1.685TyrSer: 1.685 ± 2.276
1.685TyrThr: 1.685 ± 0.882
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1188 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski