Amino acid dipepetide frequency for Invertebrate iridescent virus 6 (IIV-6) (Chilo iridescent virus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.141AlaAla: 2.141 ± 0.449
0.645AlaCys: 0.645 ± 0.088
1.367AlaAsp: 1.367 ± 0.14
1.522AlaGlu: 1.522 ± 0.19
1.973AlaPhe: 1.973 ± 0.182
2.27AlaGly: 2.27 ± 0.448
0.529AlaHis: 0.529 ± 0.078
3.469AlaIle: 3.469 ± 0.261
2.334AlaLys: 2.334 ± 0.2
3.314AlaLeu: 3.314 ± 0.257
0.928AlaMet: 0.928 ± 0.123
2.553AlaAsn: 2.553 ± 0.434
2.025AlaPro: 2.025 ± 0.402
1.315AlaGln: 1.315 ± 0.153
0.954AlaArg: 0.954 ± 0.101
3.005AlaSer: 3.005 ± 0.349
3.224AlaThr: 3.224 ± 0.842
2.295AlaVal: 2.295 ± 0.255
0.258AlaTrp: 0.258 ± 0.063
1.277AlaTyr: 1.277 ± 0.14
0.0AlaXaa: 0.0 ± 0.0
Cys
0.413CysAla: 0.413 ± 0.074
0.477CysCys: 0.477 ± 0.083
0.967CysAsp: 0.967 ± 0.13
0.709CysGlu: 0.709 ± 0.099
1.315CysPhe: 1.315 ± 0.159
0.877CysGly: 0.877 ± 0.122
0.438CysHis: 0.438 ± 0.085
1.651CysIle: 1.651 ± 0.159
1.715CysLys: 1.715 ± 0.188
1.96CysLeu: 1.96 ± 0.185
0.464CysMet: 0.464 ± 0.083
1.148CysAsn: 1.148 ± 0.123
0.709CysPro: 0.709 ± 0.117
0.709CysGln: 0.709 ± 0.106
0.709CysArg: 0.709 ± 0.101
1.406CysSer: 1.406 ± 0.156
1.07CysThr: 1.07 ± 0.122
1.186CysVal: 1.186 ± 0.121
0.142CysTrp: 0.142 ± 0.044
0.748CysTyr: 0.748 ± 0.09
0.0CysXaa: 0.0 ± 0.0
Asp
1.999AspAla: 1.999 ± 0.176
0.877AspCys: 0.877 ± 0.11
3.172AspAsp: 3.172 ± 0.257
4.204AspGlu: 4.204 ± 0.315
2.553AspPhe: 2.553 ± 0.188
1.921AspGly: 1.921 ± 0.182
0.903AspHis: 0.903 ± 0.107
4.513AspIle: 4.513 ± 0.265
3.894AspLys: 3.894 ± 0.262
4.836AspLeu: 4.836 ± 0.351
0.98AspMet: 0.98 ± 0.144
3.327AspAsn: 3.327 ± 0.208
1.625AspPro: 1.625 ± 0.177
1.161AspGln: 1.161 ± 0.116
1.534AspArg: 1.534 ± 0.149
2.863AspSer: 2.863 ± 0.211
2.153AspThr: 2.153 ± 0.189
2.811AspVal: 2.811 ± 0.186
0.529AspTrp: 0.529 ± 0.089
2.076AspTyr: 2.076 ± 0.197
0.0AspXaa: 0.0 ± 0.0
Glu
2.128GluAla: 2.128 ± 0.217
0.89GluCys: 0.89 ± 0.128
3.727GluAsp: 3.727 ± 0.295
5.519GluGlu: 5.519 ± 0.44
2.321GluPhe: 2.321 ± 0.205
2.476GluGly: 2.476 ± 0.203
1.057GluHis: 1.057 ± 0.134
5.338GluIle: 5.338 ± 0.313
5.828GluLys: 5.828 ± 0.44
4.926GluLeu: 4.926 ± 0.284
2.089GluMet: 2.089 ± 0.167
4.565GluAsn: 4.565 ± 0.362
1.805GluPro: 1.805 ± 0.204
2.025GluGln: 2.025 ± 0.186
2.166GluArg: 2.166 ± 0.191
3.275GluSer: 3.275 ± 0.266
3.611GluThr: 3.611 ± 0.304
2.605GluVal: 2.605 ± 0.193
0.787GluTrp: 0.787 ± 0.103
2.05GluTyr: 2.05 ± 0.204
0.0GluXaa: 0.0 ± 0.0
Phe
1.702PheAla: 1.702 ± 0.154
1.406PheCys: 1.406 ± 0.133
2.592PheAsp: 2.592 ± 0.182
2.553PheGlu: 2.553 ± 0.21
3.856PhePhe: 3.856 ± 0.328
2.592PheGly: 2.592 ± 0.183
1.173PheHis: 1.173 ± 0.154
4.81PheIle: 4.81 ± 0.29
5.016PheLys: 5.016 ± 0.363
5.48PheLeu: 5.48 ± 0.308
1.638PheMet: 1.638 ± 0.166
3.778PheAsn: 3.778 ± 0.198
2.386PhePro: 2.386 ± 0.177
2.037PheGln: 2.037 ± 0.182
1.689PheArg: 1.689 ± 0.168
4.603PheSer: 4.603 ± 0.301
2.27PheThr: 2.27 ± 0.177
3.636PheVal: 3.636 ± 0.278
0.477PheTrp: 0.477 ± 0.081
2.012PheTyr: 2.012 ± 0.183
0.0PheXaa: 0.0 ± 0.0
Gly
2.27GlyAla: 2.27 ± 0.478
0.787GlyCys: 0.787 ± 0.098
2.837GlyAsp: 2.837 ± 0.425
2.025GlyGlu: 2.025 ± 0.214
1.921GlyPhe: 1.921 ± 0.159
3.301GlyGly: 3.301 ± 0.441
0.554GlyHis: 0.554 ± 0.094
3.507GlyIle: 3.507 ± 0.207
3.985GlyLys: 3.985 ± 0.263
3.482GlyLeu: 3.482 ± 0.259
0.838GlyMet: 0.838 ± 0.097
3.275GlyAsn: 3.275 ± 0.32
1.496GlyPro: 1.496 ± 0.176
1.38GlyGln: 1.38 ± 0.161
1.496GlyArg: 1.496 ± 0.161
4.848GlySer: 4.848 ± 0.897
3.714GlyThr: 3.714 ± 0.684
3.082GlyVal: 3.082 ± 0.254
0.451GlyTrp: 0.451 ± 0.067
1.908GlyTyr: 1.908 ± 0.158
0.0GlyXaa: 0.0 ± 0.0
His
0.593HisAla: 0.593 ± 0.1
0.529HisCys: 0.529 ± 0.097
0.683HisAsp: 0.683 ± 0.114
0.851HisGlu: 0.851 ± 0.135
1.302HisPhe: 1.302 ± 0.134
0.529HisGly: 0.529 ± 0.095
0.632HisHis: 0.632 ± 0.104
1.444HisIle: 1.444 ± 0.13
1.38HisLys: 1.38 ± 0.166
2.141HisLeu: 2.141 ± 0.195
0.619HisMet: 0.619 ± 0.087
1.315HisAsn: 1.315 ± 0.13
0.864HisPro: 0.864 ± 0.107
0.761HisGln: 0.761 ± 0.098
0.774HisArg: 0.774 ± 0.096
1.161HisSer: 1.161 ± 0.114
0.98HisThr: 0.98 ± 0.138
1.083HisVal: 1.083 ± 0.147
0.168HisTrp: 0.168 ± 0.04
0.967HisTyr: 0.967 ± 0.112
0.0HisXaa: 0.0 ± 0.0
Ile
3.005IleAla: 3.005 ± 0.269
1.779IleCys: 1.779 ± 0.179
4.436IleAsp: 4.436 ± 0.304
5.442IleGlu: 5.442 ± 0.362
5.248IlePhe: 5.248 ± 0.314
3.688IleGly: 3.688 ± 0.364
2.115IleHis: 2.115 ± 0.185
7.582IleIle: 7.582 ± 0.415
8.111IleLys: 8.111 ± 0.401
8.498IleLeu: 8.498 ± 0.438
2.747IleMet: 2.747 ± 0.205
6.228IleAsn: 6.228 ± 0.364
3.495IlePro: 3.495 ± 0.207
3.211IleGln: 3.211 ± 0.262
2.734IleArg: 2.734 ± 0.233
6.847IleSer: 6.847 ± 0.342
4.475IleThr: 4.475 ± 0.378
4.539IleVal: 4.539 ± 0.264
0.645IleTrp: 0.645 ± 0.094
3.314IleTyr: 3.314 ± 0.25
0.0IleXaa: 0.0 ± 0.0
Lys
2.682LysAla: 2.682 ± 0.191
1.663LysCys: 1.663 ± 0.191
4.294LysAsp: 4.294 ± 0.272
6.228LysGlu: 6.228 ± 0.429
3.959LysPhe: 3.959 ± 0.311
2.837LysGly: 2.837 ± 0.226
1.689LysHis: 1.689 ± 0.156
8.846LysIle: 8.846 ± 0.485
8.73LysLys: 8.73 ± 0.526
8.008LysLeu: 8.008 ± 0.419
2.424LysMet: 2.424 ± 0.216
6.809LysAsn: 6.809 ± 0.396
2.54LysPro: 2.54 ± 0.257
3.185LysGln: 3.185 ± 0.249
3.74LysArg: 3.74 ± 0.289
5.338LysSer: 5.338 ± 0.325
5.003LysThr: 5.003 ± 0.343
4.139LysVal: 4.139 ± 0.272
0.954LysTrp: 0.954 ± 0.115
3.765LysTyr: 3.765 ± 0.311
0.0LysXaa: 0.0 ± 0.0
Leu
3.108LeuAla: 3.108 ± 0.441
1.805LeuCys: 1.805 ± 0.173
4.139LeuAsp: 4.139 ± 0.239
5.751LeuGlu: 5.751 ± 0.37
5.841LeuPhe: 5.841 ± 0.379
4.036LeuGly: 4.036 ± 0.572
1.715LeuHis: 1.715 ± 0.171
8.188LeuIle: 8.188 ± 0.339
9.336LeuLys: 9.336 ± 0.527
10.045LeuLeu: 10.045 ± 0.5
2.579LeuMet: 2.579 ± 0.197
7.505LeuAsn: 7.505 ± 0.402
3.675LeuPro: 3.675 ± 0.225
3.907LeuGln: 3.907 ± 0.238
3.056LeuArg: 3.056 ± 0.234
8.15LeuSer: 8.15 ± 0.596
5.738LeuThr: 5.738 ± 0.494
3.701LeuVal: 3.701 ± 0.229
0.838LeuTrp: 0.838 ± 0.103
4.165LeuTyr: 4.165 ± 0.287
0.0LeuXaa: 0.0 ± 0.0
Met
1.457MetAla: 1.457 ± 0.221
0.619MetCys: 0.619 ± 0.103
1.457MetAsp: 1.457 ± 0.157
1.741MetGlu: 1.741 ± 0.144
1.341MetPhe: 1.341 ± 0.147
1.122MetGly: 1.122 ± 0.128
0.387MetHis: 0.387 ± 0.07
1.896MetIle: 1.896 ± 0.17
2.411MetLys: 2.411 ± 0.208
2.837MetLeu: 2.837 ± 0.195
0.825MetMet: 0.825 ± 0.099
1.844MetAsn: 1.844 ± 0.178
0.748MetPro: 0.748 ± 0.102
0.606MetGln: 0.606 ± 0.098
0.877MetArg: 0.877 ± 0.089
1.779MetSer: 1.779 ± 0.182
1.199MetThr: 1.199 ± 0.119
1.444MetVal: 1.444 ± 0.13
0.284MetTrp: 0.284 ± 0.069
1.173MetTyr: 1.173 ± 0.126
0.0MetXaa: 0.0 ± 0.0
Asn
3.043AsnAla: 3.043 ± 0.245
1.199AsnCys: 1.199 ± 0.129
3.662AsnAsp: 3.662 ± 0.245
4.191AsnGlu: 4.191 ± 0.347
3.933AsnPhe: 3.933 ± 0.292
4.178AsnGly: 4.178 ± 0.284
1.289AsnHis: 1.289 ± 0.141
6.796AsnIle: 6.796 ± 0.322
5.622AsnLys: 5.622 ± 0.303
7.221AsnLeu: 7.221 ± 0.436
1.586AsnMet: 1.586 ± 0.17
5.996AsnAsn: 5.996 ± 0.343
2.592AsnPro: 2.592 ± 0.244
2.527AsnGln: 2.527 ± 0.2
1.986AsnArg: 1.986 ± 0.209
4.72AsnSer: 4.72 ± 0.355
3.572AsnThr: 3.572 ± 0.218
3.997AsnVal: 3.997 ± 0.256
0.529AsnTrp: 0.529 ± 0.099
2.682AsnTyr: 2.682 ± 0.224
0.0AsnXaa: 0.0 ± 0.0
Pro
1.522ProAla: 1.522 ± 0.31
0.49ProCys: 0.49 ± 0.087
1.483ProAsp: 1.483 ± 0.15
1.921ProGlu: 1.921 ± 0.215
2.36ProPhe: 2.36 ± 0.2
1.509ProGly: 1.509 ± 0.208
0.761ProHis: 0.761 ± 0.1
3.456ProIle: 3.456 ± 0.242
2.811ProLys: 2.811 ± 0.26
3.611ProLeu: 3.611 ± 0.199
0.696ProMet: 0.696 ± 0.094
2.592ProAsn: 2.592 ± 0.21
2.321ProPro: 2.321 ± 0.287
1.393ProGln: 1.393 ± 0.155
1.676ProArg: 1.676 ± 0.261
3.314ProSer: 3.314 ± 0.285
2.863ProThr: 2.863 ± 0.557
2.231ProVal: 2.231 ± 0.233
0.297ProTrp: 0.297 ± 0.064
1.522ProTyr: 1.522 ± 0.131
0.0ProXaa: 0.0 ± 0.0
Gln
0.928GlnAla: 0.928 ± 0.118
0.529GlnCys: 0.529 ± 0.083
1.238GlnAsp: 1.238 ± 0.141
1.921GlnGlu: 1.921 ± 0.191
1.47GlnPhe: 1.47 ± 0.136
1.032GlnGly: 1.032 ± 0.105
0.916GlnHis: 0.916 ± 0.103
3.456GlnIle: 3.456 ± 0.349
3.366GlnLys: 3.366 ± 0.238
4.204GlnLeu: 4.204 ± 0.476
1.019GlnMet: 1.019 ± 0.133
2.772GlnAsn: 2.772 ± 0.213
1.225GlnPro: 1.225 ± 0.17
1.702GlnGln: 1.702 ± 0.212
1.406GlnArg: 1.406 ± 0.146
2.153GlnSer: 2.153 ± 0.189
1.883GlnThr: 1.883 ± 0.153
1.741GlnVal: 1.741 ± 0.156
0.464GlnTrp: 0.464 ± 0.083
1.418GlnTyr: 1.418 ± 0.143
0.0GlnXaa: 0.0 ± 0.0
Arg
1.251ArgAla: 1.251 ± 0.156
0.761ArgCys: 0.761 ± 0.112
1.496ArgAsp: 1.496 ± 0.162
2.373ArgGlu: 2.373 ± 0.218
2.218ArgPhe: 2.218 ± 0.204
1.393ArgGly: 1.393 ± 0.144
0.722ArgHis: 0.722 ± 0.106
2.205ArgIle: 2.205 ± 0.192
3.082ArgLys: 3.082 ± 0.275
3.275ArgLeu: 3.275 ± 0.259
0.812ArgMet: 0.812 ± 0.107
2.257ArgAsn: 2.257 ± 0.232
1.122ArgPro: 1.122 ± 0.119
1.277ArgGln: 1.277 ± 0.164
2.515ArgArg: 2.515 ± 0.401
2.837ArgSer: 2.837 ± 0.389
1.728ArgThr: 1.728 ± 0.148
1.599ArgVal: 1.599 ± 0.175
0.284ArgTrp: 0.284 ± 0.065
1.418ArgTyr: 1.418 ± 0.148
0.0ArgXaa: 0.0 ± 0.0
Ser
2.798SerAla: 2.798 ± 0.423
1.457SerCys: 1.457 ± 0.179
3.25SerAsp: 3.25 ± 0.255
3.843SerGlu: 3.843 ± 0.328
4.603SerPhe: 4.603 ± 0.246
4.887SerGly: 4.887 ± 0.996
1.199SerHis: 1.199 ± 0.124
6.564SerIle: 6.564 ± 0.281
5.983SerLys: 5.983 ± 0.273
7.518SerLeu: 7.518 ± 0.369
1.612SerMet: 1.612 ± 0.176
4.139SerAsn: 4.139 ± 0.214
3.546SerPro: 3.546 ± 0.405
2.721SerGln: 2.721 ± 0.305
2.386SerArg: 2.386 ± 0.252
8.446SerSer: 8.446 ± 0.728
4.926SerThr: 4.926 ± 0.615
4.062SerVal: 4.062 ± 0.419
0.632SerTrp: 0.632 ± 0.088
2.656SerTyr: 2.656 ± 0.192
0.0SerXaa: 0.0 ± 0.0
Thr
2.179ThrAla: 2.179 ± 0.513
0.903ThrCys: 0.903 ± 0.124
2.115ThrAsp: 2.115 ± 0.148
2.656ThrGlu: 2.656 ± 0.215
3.417ThrPhe: 3.417 ± 0.192
3.25ThrGly: 3.25 ± 0.479
0.709ThrHis: 0.709 ± 0.11
5.764ThrIle: 5.764 ± 0.284
4.487ThrLys: 4.487 ± 0.29
5.674ThrLeu: 5.674 ± 0.632
1.483ThrMet: 1.483 ± 0.159
3.804ThrAsn: 3.804 ± 0.251
2.643ThrPro: 2.643 ± 0.254
1.689ThrGln: 1.689 ± 0.171
1.805ThrArg: 1.805 ± 0.17
4.99ThrSer: 4.99 ± 0.643
3.985ThrThr: 3.985 ± 0.485
3.74ThrVal: 3.74 ± 0.532
0.529ThrTrp: 0.529 ± 0.093
2.089ThrTyr: 2.089 ± 0.163
0.0ThrXaa: 0.0 ± 0.0
Val
2.605ValAla: 2.605 ± 0.317
1.083ValCys: 1.083 ± 0.14
2.785ValAsp: 2.785 ± 0.193
3.082ValGlu: 3.082 ± 0.236
2.966ValPhe: 2.966 ± 0.206
2.618ValGly: 2.618 ± 0.356
1.019ValHis: 1.019 ± 0.109
4.062ValIle: 4.062 ± 0.227
4.397ValLys: 4.397 ± 0.289
5.171ValLeu: 5.171 ± 0.29
1.496ValMet: 1.496 ± 0.157
3.778ValAsn: 3.778 ± 0.279
2.527ValPro: 2.527 ± 0.294
1.638ValGln: 1.638 ± 0.135
1.56ValArg: 1.56 ± 0.147
4.139ValSer: 4.139 ± 0.23
3.095ValThr: 3.095 ± 0.257
3.224ValVal: 3.224 ± 0.234
0.413ValTrp: 0.413 ± 0.074
1.96ValTyr: 1.96 ± 0.162
0.0ValXaa: 0.0 ± 0.0
Trp
0.297TrpAla: 0.297 ± 0.061
0.181TrpCys: 0.181 ± 0.049
0.387TrpAsp: 0.387 ± 0.073
0.413TrpGlu: 0.413 ± 0.078
0.671TrpPhe: 0.671 ± 0.083
0.361TrpGly: 0.361 ± 0.081
0.116TrpHis: 0.116 ± 0.038
0.774TrpIle: 0.774 ± 0.088
0.774TrpLys: 0.774 ± 0.096
0.98TrpLeu: 0.98 ± 0.106
0.206TrpMet: 0.206 ± 0.051
0.825TrpAsn: 0.825 ± 0.105
0.116TrpPro: 0.116 ± 0.036
0.335TrpGln: 0.335 ± 0.069
0.413TrpArg: 0.413 ± 0.08
0.645TrpSer: 0.645 ± 0.104
0.593TrpThr: 0.593 ± 0.103
0.348TrpVal: 0.348 ± 0.074
0.103TrpTrp: 0.103 ± 0.035
0.426TrpTyr: 0.426 ± 0.078
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.277TyrAla: 1.277 ± 0.144
0.735TyrCys: 0.735 ± 0.111
1.844TyrAsp: 1.844 ± 0.172
2.244TyrGlu: 2.244 ± 0.196
2.437TyrPhe: 2.437 ± 0.196
2.282TyrGly: 2.282 ± 0.244
0.851TyrHis: 0.851 ± 0.122
3.817TyrIle: 3.817 ± 0.298
3.572TyrLys: 3.572 ± 0.276
4.113TyrLeu: 4.113 ± 0.278
0.993TyrMet: 0.993 ± 0.103
2.811TyrAsn: 2.811 ± 0.264
1.367TyrPro: 1.367 ± 0.131
1.264TyrGln: 1.264 ± 0.146
1.148TyrArg: 1.148 ± 0.128
2.708TyrSer: 2.708 ± 0.188
1.831TyrThr: 1.831 ± 0.158
2.153TyrVal: 2.153 ± 0.181
0.181TyrTrp: 0.181 ± 0.045
1.779TyrTyr: 1.779 ± 0.164
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 468 proteins (77551 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski