Amino acid dipepetide frequency for Hubei diptera virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.322AlaAla: 8.322 ± 1.498
0.0AlaCys: 0.0 ± 0.0
4.854AlaAsp: 4.854 ± 1.754
3.467AlaGlu: 3.467 ± 1.374
2.08AlaPhe: 2.08 ± 0.247
9.015AlaGly: 9.015 ± 3.271
3.467AlaHis: 3.467 ± 1.638
2.774AlaIle: 2.774 ± 1.69
9.015AlaLys: 9.015 ± 1.813
9.015AlaLeu: 9.015 ± 1.813
2.774AlaMet: 2.774 ± 1.313
1.387AlaAsn: 1.387 ± 1.026
2.08AlaPro: 2.08 ± 1.228
4.161AlaGln: 4.161 ± 1.573
4.161AlaArg: 4.161 ± 0.655
6.935AlaSer: 6.935 ± 3.284
4.854AlaThr: 4.854 ± 1.1
1.387AlaVal: 1.387 ± 0.603
1.387AlaTrp: 1.387 ± 0.603
4.161AlaTyr: 4.161 ± 1.3
0.0AlaXaa: 0.0 ± 0.0
Cys
1.387CysAla: 1.387 ± 0.603
0.693CysCys: 0.693 ± 0.513
0.693CysAsp: 0.693 ± 0.513
1.387CysGlu: 1.387 ± 1.026
0.0CysPhe: 0.0 ± 0.0
2.08CysGly: 2.08 ± 0.854
0.693CysHis: 0.693 ± 0.513
0.693CysIle: 0.693 ± 0.636
0.0CysLys: 0.0 ± 0.0
1.387CysLeu: 1.387 ± 0.755
0.693CysMet: 0.693 ± 0.636
0.0CysAsn: 0.0 ± 0.0
0.693CysPro: 0.693 ± 0.723
0.693CysGln: 0.693 ± 0.513
0.693CysArg: 0.693 ± 0.636
0.0CysSer: 0.0 ± 0.0
0.693CysThr: 0.693 ± 0.513
2.08CysVal: 2.08 ± 1.195
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.241AspAla: 6.241 ± 0.74
0.693AspCys: 0.693 ± 0.513
2.774AspAsp: 2.774 ± 0.754
2.08AspGlu: 2.08 ± 1.908
2.774AspPhe: 2.774 ± 0.279
1.387AspGly: 1.387 ± 0.755
1.387AspHis: 1.387 ± 0.564
2.08AspIle: 2.08 ± 0.87
1.387AspLys: 1.387 ± 1.272
6.241AspLeu: 6.241 ± 1.52
2.08AspMet: 2.08 ± 1.087
0.693AspAsn: 0.693 ± 0.636
4.161AspPro: 4.161 ± 1.096
0.693AspGln: 0.693 ± 0.636
2.08AspArg: 2.08 ± 1.228
6.241AspSer: 6.241 ± 2.581
3.467AspThr: 3.467 ± 1.638
2.08AspVal: 2.08 ± 0.87
1.387AspTrp: 1.387 ± 0.564
1.387AspTyr: 1.387 ± 0.603
0.0AspXaa: 0.0 ± 0.0
Glu
4.854GluAla: 4.854 ± 1.246
0.693GluCys: 0.693 ± 0.513
4.161GluAsp: 4.161 ± 1.3
4.854GluGlu: 4.854 ± 1.813
1.387GluPhe: 1.387 ± 0.564
2.774GluGly: 2.774 ± 0.279
0.693GluHis: 0.693 ± 0.636
4.161GluIle: 4.161 ± 0.493
4.854GluLys: 4.854 ± 1.726
2.774GluLeu: 2.774 ± 0.279
2.08GluMet: 2.08 ± 1.566
1.387GluAsn: 1.387 ± 1.026
7.628GluPro: 7.628 ± 1.302
0.693GluGln: 0.693 ± 0.723
3.467GluArg: 3.467 ± 0.788
4.854GluSer: 4.854 ± 1.072
4.854GluThr: 4.854 ± 1.022
4.161GluVal: 4.161 ± 0.493
0.693GluTrp: 0.693 ± 0.636
1.387GluTyr: 1.387 ± 1.026
0.0GluXaa: 0.0 ± 0.0
Phe
2.08PheAla: 2.08 ± 1.195
0.0PheCys: 0.0 ± 0.0
2.08PheAsp: 2.08 ± 1.087
1.387PheGlu: 1.387 ± 0.755
0.693PhePhe: 0.693 ± 0.723
2.08PheGly: 2.08 ± 1.335
0.0PheHis: 0.0 ± 0.0
0.693PheIle: 0.693 ± 0.723
2.774PheLys: 2.774 ± 0.754
2.774PheLeu: 2.774 ± 1.128
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
0.0PhePro: 0.0 ± 0.0
0.693PheGln: 0.693 ± 0.513
2.774PheArg: 2.774 ± 1.69
4.854PheSer: 4.854 ± 1.246
2.08PheThr: 2.08 ± 1.335
5.548PheVal: 5.548 ± 0.558
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.161GlyAla: 4.161 ± 1.3
1.387GlyCys: 1.387 ± 0.755
2.774GlyAsp: 2.774 ± 0.279
5.548GlyGlu: 5.548 ± 2.69
2.08GlyPhe: 2.08 ± 0.247
3.467GlyGly: 3.467 ± 1.0
1.387GlyHis: 1.387 ± 0.755
2.08GlyIle: 2.08 ± 0.87
3.467GlyLys: 3.467 ± 2.709
2.774GlyLeu: 2.774 ± 0.279
3.467GlyMet: 3.467 ± 0.485
2.774GlyAsn: 2.774 ± 0.921
2.08GlyPro: 2.08 ± 0.854
1.387GlyGln: 1.387 ± 0.564
1.387GlyArg: 1.387 ± 0.603
9.015GlySer: 9.015 ± 3.681
2.08GlyThr: 2.08 ± 1.539
5.548GlyVal: 5.548 ± 1.572
4.161GlyTrp: 4.161 ± 2.265
4.161GlyTyr: 4.161 ± 0.655
0.0GlyXaa: 0.0 ± 0.0
His
4.161HisAla: 4.161 ± 2.003
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.693HisGlu: 0.693 ± 0.513
0.693HisPhe: 0.693 ± 0.723
1.387HisGly: 1.387 ± 0.603
0.0HisHis: 0.0 ± 0.0
0.693HisIle: 0.693 ± 0.636
1.387HisLys: 1.387 ± 0.564
1.387HisLeu: 1.387 ± 0.755
0.693HisMet: 0.693 ± 0.636
0.0HisAsn: 0.0 ± 0.0
0.693HisPro: 0.693 ± 0.513
2.08HisGln: 2.08 ± 0.854
2.774HisArg: 2.774 ± 0.754
0.693HisSer: 0.693 ± 0.723
1.387HisThr: 1.387 ± 0.603
2.774HisVal: 2.774 ± 2.052
0.693HisTrp: 0.693 ± 0.723
1.387HisTyr: 1.387 ± 0.755
0.0HisXaa: 0.0 ± 0.0
Ile
4.854IleAla: 4.854 ± 1.931
0.693IleCys: 0.693 ± 0.513
3.467IleAsp: 3.467 ± 2.36
1.387IleGlu: 1.387 ± 0.603
0.693IlePhe: 0.693 ± 0.513
4.161IleGly: 4.161 ± 1.399
0.0IleHis: 0.0 ± 0.0
1.387IleIle: 1.387 ± 0.564
2.08IleLys: 2.08 ± 1.539
2.08IleLeu: 2.08 ± 0.87
1.387IleMet: 1.387 ± 0.564
0.0IleAsn: 0.0 ± 0.0
3.467IlePro: 3.467 ± 0.666
2.774IleGln: 2.774 ± 1.923
2.08IleArg: 2.08 ± 1.087
2.774IleSer: 2.774 ± 1.313
1.387IleThr: 1.387 ± 1.026
3.467IleVal: 3.467 ± 1.374
0.693IleTrp: 0.693 ± 0.513
1.387IleTyr: 1.387 ± 0.755
0.0IleXaa: 0.0 ± 0.0
Lys
4.161LysAla: 4.161 ± 1.573
1.387LysCys: 1.387 ± 0.564
2.774LysAsp: 2.774 ± 0.754
5.548LysGlu: 5.548 ± 1.245
2.08LysPhe: 2.08 ± 0.247
2.08LysGly: 2.08 ± 0.247
3.467LysHis: 3.467 ± 1.793
2.774LysIle: 2.774 ± 1.274
8.322LysLys: 8.322 ± 3.281
5.548LysLeu: 5.548 ± 1.19
0.693LysMet: 0.693 ± 0.435
2.774LysAsn: 2.774 ± 2.052
4.854LysPro: 4.854 ± 1.139
2.08LysGln: 2.08 ± 1.539
4.854LysArg: 4.854 ± 0.119
4.161LysSer: 4.161 ± 1.399
3.467LysThr: 3.467 ± 1.793
4.161LysVal: 4.161 ± 1.096
2.774LysTrp: 2.774 ± 0.921
2.08LysTyr: 2.08 ± 1.195
0.0LysXaa: 0.0 ± 0.0
Leu
7.628LeuAla: 7.628 ± 0.984
2.774LeuCys: 2.774 ± 0.279
2.08LeuAsp: 2.08 ± 0.247
7.628LeuGlu: 7.628 ± 2.028
5.548LeuPhe: 5.548 ± 2.359
4.854LeuGly: 4.854 ± 1.072
2.08LeuHis: 2.08 ± 1.087
3.467LeuIle: 3.467 ± 1.374
4.161LeuLys: 4.161 ± 0.493
11.789LeuLeu: 11.789 ± 2.557
1.387LeuMet: 1.387 ± 0.603
2.08LeuAsn: 2.08 ± 1.228
4.854LeuPro: 4.854 ± 1.1
3.467LeuGln: 3.467 ± 1.638
6.935LeuArg: 6.935 ± 1.795
2.774LeuSer: 2.774 ± 1.205
4.161LeuThr: 4.161 ± 1.3
5.548LeuVal: 5.548 ± 2.326
1.387LeuTrp: 1.387 ± 0.755
3.467LeuTyr: 3.467 ± 1.611
0.0LeuXaa: 0.0 ± 0.0
Met
2.08MetAla: 2.08 ± 0.87
0.0MetCys: 0.0 ± 0.0
0.693MetAsp: 0.693 ± 0.513
0.693MetGlu: 0.693 ± 0.513
0.693MetPhe: 0.693 ± 0.636
2.774MetGly: 2.774 ± 1.128
1.387MetHis: 1.387 ± 0.603
0.693MetIle: 0.693 ± 0.513
2.08MetLys: 2.08 ± 0.87
2.774MetLeu: 2.774 ± 1.759
0.0MetMet: 0.0 ± 0.0
1.387MetAsn: 1.387 ± 1.272
0.693MetPro: 0.693 ± 0.636
1.387MetGln: 1.387 ± 0.564
2.08MetArg: 2.08 ± 1.087
1.387MetSer: 1.387 ± 1.026
0.693MetThr: 0.693 ± 0.636
3.467MetVal: 3.467 ± 1.638
2.08MetTrp: 2.08 ± 0.247
0.693MetTyr: 0.693 ± 0.636
0.0MetXaa: 0.0 ± 0.0
Asn
2.774AsnAla: 2.774 ± 1.205
0.0AsnCys: 0.0 ± 0.0
1.387AsnAsp: 1.387 ± 1.446
4.161AsnGlu: 4.161 ± 1.096
0.693AsnPhe: 0.693 ± 0.723
2.08AsnGly: 2.08 ± 0.247
1.387AsnHis: 1.387 ± 0.564
0.693AsnIle: 0.693 ± 0.513
1.387AsnLys: 1.387 ± 0.564
0.693AsnLeu: 0.693 ± 0.513
0.693AsnMet: 0.693 ± 0.636
1.387AsnAsn: 1.387 ± 0.603
1.387AsnPro: 1.387 ± 0.564
0.0AsnGln: 0.0 ± 0.0
1.387AsnArg: 1.387 ± 1.026
4.161AsnSer: 4.161 ± 0.655
2.08AsnThr: 2.08 ± 0.87
0.693AsnVal: 0.693 ± 0.513
0.693AsnTrp: 0.693 ± 0.513
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.774ProAla: 2.774 ± 1.923
0.0ProCys: 0.0 ± 0.0
5.548ProAsp: 5.548 ± 0.803
6.241ProGlu: 6.241 ± 1.065
1.387ProPhe: 1.387 ± 0.755
4.161ProGly: 4.161 ± 0.655
0.0ProHis: 0.0 ± 0.0
3.467ProIle: 3.467 ± 0.788
4.854ProLys: 4.854 ± 1.813
1.387ProLeu: 1.387 ± 1.272
1.387ProMet: 1.387 ± 0.683
2.08ProAsn: 2.08 ± 1.335
0.0ProPro: 0.0 ± 0.0
0.693ProGln: 0.693 ± 0.723
2.08ProArg: 2.08 ± 1.087
4.161ProSer: 4.161 ± 0.655
2.774ProThr: 2.774 ± 1.128
2.774ProVal: 2.774 ± 2.009
0.693ProTrp: 0.693 ± 0.513
2.774ProTyr: 2.774 ± 1.51
0.0ProXaa: 0.0 ± 0.0
Gln
3.467GlnAla: 3.467 ± 1.387
0.693GlnCys: 0.693 ± 0.723
3.467GlnAsp: 3.467 ± 0.666
2.08GlnGlu: 2.08 ± 0.247
1.387GlnPhe: 1.387 ± 0.755
0.693GlnGly: 0.693 ± 0.513
2.08GlnHis: 2.08 ± 0.247
0.693GlnIle: 0.693 ± 0.636
2.08GlnLys: 2.08 ± 0.247
1.387GlnLeu: 1.387 ± 1.446
1.387GlnMet: 1.387 ± 1.026
1.387GlnAsn: 1.387 ± 1.026
1.387GlnPro: 1.387 ± 0.603
0.693GlnGln: 0.693 ± 0.723
1.387GlnArg: 1.387 ± 0.755
2.08GlnSer: 2.08 ± 0.854
2.774GlnThr: 2.774 ± 1.205
1.387GlnVal: 1.387 ± 1.026
2.08GlnTrp: 2.08 ± 1.087
2.774GlnTyr: 2.774 ± 1.128
0.0GlnXaa: 0.0 ± 0.0
Arg
4.854ArgAla: 4.854 ± 1.246
0.693ArgCys: 0.693 ± 0.513
0.693ArgAsp: 0.693 ± 0.636
1.387ArgGlu: 1.387 ± 0.603
2.08ArgPhe: 2.08 ± 1.195
2.774ArgGly: 2.774 ± 1.128
0.0ArgHis: 0.0 ± 0.0
2.08ArgIle: 2.08 ± 1.335
2.08ArgLys: 2.08 ± 0.247
8.322ArgLeu: 8.322 ± 0.987
1.387ArgMet: 1.387 ± 1.272
2.08ArgAsn: 2.08 ± 1.087
1.387ArgPro: 1.387 ± 1.446
3.467ArgGln: 3.467 ± 2.36
4.854ArgArg: 4.854 ± 0.924
4.854ArgSer: 4.854 ± 1.813
1.387ArgThr: 1.387 ± 0.564
11.096ArgVal: 11.096 ± 0.39
1.387ArgTrp: 1.387 ± 0.755
1.387ArgTyr: 1.387 ± 0.564
0.0ArgXaa: 0.0 ± 0.0
Ser
6.241SerAla: 6.241 ± 1.59
0.693SerCys: 0.693 ± 0.513
2.08SerAsp: 2.08 ± 0.854
4.854SerGlu: 4.854 ± 1.813
1.387SerPhe: 1.387 ± 1.026
7.628SerGly: 7.628 ± 0.984
2.08SerHis: 2.08 ± 1.228
3.467SerIle: 3.467 ± 1.373
6.935SerLys: 6.935 ± 1.331
8.322SerLeu: 8.322 ± 2.723
3.467SerMet: 3.467 ± 1.744
2.08SerAsn: 2.08 ± 0.854
3.467SerPro: 3.467 ± 1.0
3.467SerGln: 3.467 ± 0.788
2.08SerArg: 2.08 ± 0.87
8.322SerSer: 8.322 ± 3.037
4.161SerThr: 4.161 ± 1.362
6.935SerVal: 6.935 ± 2.465
2.08SerTrp: 2.08 ± 0.247
1.387SerTyr: 1.387 ± 0.603
0.0SerXaa: 0.0 ± 0.0
Thr
6.241ThrAla: 6.241 ± 2.021
0.693ThrCys: 0.693 ± 0.513
2.08ThrAsp: 2.08 ± 0.247
0.693ThrGlu: 0.693 ± 0.636
1.387ThrPhe: 1.387 ± 1.446
4.854ThrGly: 4.854 ± 1.96
0.693ThrHis: 0.693 ± 0.513
4.161ThrIle: 4.161 ± 0.493
4.161ThrLys: 4.161 ± 1.3
4.854ThrLeu: 4.854 ± 2.168
0.693ThrMet: 0.693 ± 0.636
1.387ThrAsn: 1.387 ± 0.564
2.08ThrPro: 2.08 ± 1.335
1.387ThrGln: 1.387 ± 1.026
3.467ThrArg: 3.467 ± 1.638
4.161ThrSer: 4.161 ± 0.655
4.161ThrThr: 4.161 ± 2.456
4.854ThrVal: 4.854 ± 1.246
0.693ThrTrp: 0.693 ± 0.636
0.693ThrTyr: 0.693 ± 0.513
0.0ThrXaa: 0.0 ± 0.0
Val
6.241ValAla: 6.241 ± 1.59
2.08ValCys: 2.08 ± 1.335
4.161ValAsp: 4.161 ± 1.692
4.854ValGlu: 4.854 ± 1.1
1.387ValPhe: 1.387 ± 0.564
4.854ValGly: 4.854 ± 0.119
1.387ValHis: 1.387 ± 0.755
1.387ValIle: 1.387 ± 0.603
4.161ValLys: 4.161 ± 1.096
9.709ValLeu: 9.709 ± 1.853
2.08ValMet: 2.08 ± 1.087
4.854ValAsn: 4.854 ± 1.022
5.548ValPro: 5.548 ± 1.572
3.467ValGln: 3.467 ± 1.387
7.628ValArg: 7.628 ± 2.968
3.467ValSer: 3.467 ± 0.666
3.467ValThr: 3.467 ± 0.666
8.322ValVal: 8.322 ± 0.368
0.693ValTrp: 0.693 ± 0.513
0.693ValTyr: 0.693 ± 0.513
0.0ValXaa: 0.0 ± 0.0
Trp
1.387TrpAla: 1.387 ± 0.603
0.0TrpCys: 0.0 ± 0.0
3.467TrpAsp: 3.467 ± 1.373
2.774TrpGlu: 2.774 ± 1.923
0.693TrpPhe: 0.693 ± 0.636
0.693TrpGly: 0.693 ± 0.513
0.0TrpHis: 0.0 ± 0.0
0.693TrpIle: 0.693 ± 0.513
2.774TrpLys: 2.774 ± 1.69
2.774TrpLeu: 2.774 ± 1.128
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.693TrpPro: 0.693 ± 0.636
0.0TrpGln: 0.0 ± 0.0
0.693TrpArg: 0.693 ± 0.723
2.774TrpSer: 2.774 ± 1.51
2.08TrpThr: 2.08 ± 0.247
0.693TrpVal: 0.693 ± 0.723
0.0TrpTrp: 0.0 ± 0.0
1.387TrpTyr: 1.387 ± 0.603
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.387TyrAla: 1.387 ± 1.272
1.387TyrCys: 1.387 ± 1.272
2.08TyrAsp: 2.08 ± 0.87
1.387TyrGlu: 1.387 ± 0.603
1.387TyrPhe: 1.387 ± 0.603
1.387TyrGly: 1.387 ± 0.564
1.387TyrHis: 1.387 ± 0.755
2.08TyrIle: 2.08 ± 0.247
2.08TyrLys: 2.08 ± 0.854
2.08TyrLeu: 2.08 ± 1.087
0.693TyrMet: 0.693 ± 0.723
0.0TyrAsn: 0.0 ± 0.0
2.08TyrPro: 2.08 ± 1.087
2.08TyrGln: 2.08 ± 1.539
1.387TyrArg: 1.387 ± 1.272
3.467TyrSer: 3.467 ± 0.788
1.387TyrThr: 1.387 ± 1.446
3.467TyrVal: 3.467 ± 0.788
0.0TyrTrp: 0.0 ± 0.0
0.693TyrTyr: 0.693 ± 0.513
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1443 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski