Amino acid dipepetide frequency for Chimpanzee herpesvirus strain 105640

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.404AlaAla: 19.404 ± 1.487
2.834AlaCys: 2.834 ± 0.242
6.179AlaAsp: 6.179 ± 0.399
5.974AlaGlu: 5.974 ± 0.534
4.136AlaPhe: 4.136 ± 0.391
9.779AlaGly: 9.779 ± 0.656
3.396AlaHis: 3.396 ± 0.279
3.345AlaIle: 3.345 ± 0.265
1.813AlaLys: 1.813 ± 0.24
13.174AlaLeu: 13.174 ± 1.023
1.762AlaMet: 1.762 ± 0.22
2.221AlaAsn: 2.221 ± 0.309
11.642AlaPro: 11.642 ± 0.859
3.268AlaGln: 3.268 ± 0.275
10.877AlaArg: 10.877 ± 0.669
8.706AlaSer: 8.706 ± 0.394
6.791AlaThr: 6.791 ± 0.52
9.498AlaVal: 9.498 ± 0.611
1.557AlaTrp: 1.557 ± 0.174
2.706AlaTyr: 2.706 ± 0.246
0.0AlaXaa: 0.0 ± 0.0
Cys
2.094CysAla: 2.094 ± 0.234
0.357CysCys: 0.357 ± 0.09
0.817CysAsp: 0.817 ± 0.176
0.894CysGlu: 0.894 ± 0.148
0.74CysPhe: 0.74 ± 0.145
1.251CysGly: 1.251 ± 0.153
0.332CysHis: 0.332 ± 0.093
0.613CysIle: 0.613 ± 0.135
0.306CysLys: 0.306 ± 0.099
2.272CysLeu: 2.272 ± 0.299
0.46CysMet: 0.46 ± 0.114
0.536CysAsn: 0.536 ± 0.117
1.404CysPro: 1.404 ± 0.218
0.434CysGln: 0.434 ± 0.095
1.557CysArg: 1.557 ± 0.242
0.868CysSer: 0.868 ± 0.129
1.047CysThr: 1.047 ± 0.167
1.787CysVal: 1.787 ± 0.186
0.153CysTrp: 0.153 ± 0.063
0.485CysTyr: 0.485 ± 0.1
0.0CysXaa: 0.0 ± 0.0
Asp
7.174AspAla: 7.174 ± 0.69
1.072AspCys: 1.072 ± 0.166
3.957AspAsp: 3.957 ± 0.593
2.655AspGlu: 2.655 ± 0.226
1.379AspPhe: 1.379 ± 0.223
3.83AspGly: 3.83 ± 0.382
1.226AspHis: 1.226 ± 0.192
1.915AspIle: 1.915 ± 0.28
0.613AspLys: 0.613 ± 0.165
4.698AspLeu: 4.698 ± 0.348
0.74AspMet: 0.74 ± 0.132
1.021AspAsn: 1.021 ± 0.176
4.774AspPro: 4.774 ± 0.324
1.226AspGln: 1.226 ± 0.133
3.191AspArg: 3.191 ± 0.3
3.421AspSer: 3.421 ± 0.341
2.808AspThr: 2.808 ± 0.238
4.187AspVal: 4.187 ± 0.328
0.766AspTrp: 0.766 ± 0.119
0.97AspTyr: 0.97 ± 0.149
0.0AspXaa: 0.0 ± 0.0
Glu
7.098GluAla: 7.098 ± 0.446
0.766GluCys: 0.766 ± 0.17
3.013GluAsp: 3.013 ± 0.286
2.63GluGlu: 2.63 ± 0.27
1.915GluPhe: 1.915 ± 0.324
3.37GluGly: 3.37 ± 0.378
1.353GluHis: 1.353 ± 0.16
1.43GluIle: 1.43 ± 0.164
0.791GluLys: 0.791 ± 0.168
5.004GluLeu: 5.004 ± 0.457
0.945GluMet: 0.945 ± 0.132
1.277GluAsn: 1.277 ± 0.186
2.834GluPro: 2.834 ± 0.289
1.685GluGln: 1.685 ± 0.215
3.932GluArg: 3.932 ± 0.317
2.604GluSer: 2.604 ± 0.287
3.217GluThr: 3.217 ± 0.259
2.834GluVal: 2.834 ± 0.247
0.46GluTrp: 0.46 ± 0.09
1.2GluTyr: 1.2 ± 0.14
0.0GluXaa: 0.0 ± 0.0
Phe
3.677PheAla: 3.677 ± 0.343
0.919PheCys: 0.919 ± 0.137
2.119PheAsp: 2.119 ± 0.254
1.966PheGlu: 1.966 ± 0.238
1.532PhePhe: 1.532 ± 0.203
2.528PheGly: 2.528 ± 0.249
0.843PheHis: 0.843 ± 0.139
1.251PheIle: 1.251 ± 0.209
0.817PheLys: 0.817 ± 0.223
3.753PheLeu: 3.753 ± 0.4
0.613PheMet: 0.613 ± 0.117
0.843PheAsn: 0.843 ± 0.177
2.017PhePro: 2.017 ± 0.196
0.715PheGln: 0.715 ± 0.132
2.298PheArg: 2.298 ± 0.27
2.221PheSer: 2.221 ± 0.305
1.226PheThr: 1.226 ± 0.207
3.472PheVal: 3.472 ± 0.34
0.46PheTrp: 0.46 ± 0.11
0.97PheTyr: 0.97 ± 0.17
0.0PheXaa: 0.0 ± 0.0
Gly
10.008GlyAla: 10.008 ± 0.657
0.919GlyCys: 0.919 ± 0.158
4.8GlyAsp: 4.8 ± 0.277
4.162GlyGlu: 4.162 ± 0.29
2.528GlyPhe: 2.528 ± 0.279
8.196GlyGly: 8.196 ± 0.63
1.813GlyHis: 1.813 ± 0.206
1.736GlyIle: 1.736 ± 0.219
0.868GlyLys: 0.868 ± 0.151
7.149GlyLeu: 7.149 ± 0.38
1.098GlyMet: 1.098 ± 0.155
1.149GlyAsn: 1.149 ± 0.235
7.736GlyPro: 7.736 ± 0.617
2.119GlyGln: 2.119 ± 0.218
6.485GlyArg: 6.485 ± 0.574
4.698GlySer: 4.698 ± 0.486
4.06GlyThr: 4.06 ± 0.358
5.336GlyVal: 5.336 ± 0.357
0.894GlyTrp: 0.894 ± 0.148
1.455GlyTyr: 1.455 ± 0.204
0.0GlyXaa: 0.0 ± 0.0
His
3.549HisAla: 3.549 ± 0.286
0.434HisCys: 0.434 ± 0.139
0.996HisAsp: 0.996 ± 0.162
1.226HisGlu: 1.226 ± 0.174
0.791HisPhe: 0.791 ± 0.189
1.94HisGly: 1.94 ± 0.223
0.919HisHis: 0.919 ± 0.161
0.945HisIle: 0.945 ± 0.202
0.383HisLys: 0.383 ± 0.106
2.247HisLeu: 2.247 ± 0.3
0.409HisMet: 0.409 ± 0.115
0.791HisAsn: 0.791 ± 0.16
2.732HisPro: 2.732 ± 0.348
0.664HisGln: 0.664 ± 0.138
2.553HisArg: 2.553 ± 0.208
1.251HisSer: 1.251 ± 0.194
1.787HisThr: 1.787 ± 0.195
1.864HisVal: 1.864 ± 0.212
0.255HisTrp: 0.255 ± 0.09
0.868HisTyr: 0.868 ± 0.193
0.0HisXaa: 0.0 ± 0.0
Ile
3.268IleAla: 3.268 ± 0.32
0.613IleCys: 0.613 ± 0.178
1.557IleAsp: 1.557 ± 0.225
1.328IleGlu: 1.328 ± 0.211
1.072IlePhe: 1.072 ± 0.199
1.506IleGly: 1.506 ± 0.195
0.894IleHis: 0.894 ± 0.162
1.098IleIle: 1.098 ± 0.198
0.843IleLys: 0.843 ± 0.217
2.706IleLeu: 2.706 ± 0.33
0.511IleMet: 0.511 ± 0.14
1.226IleAsn: 1.226 ± 0.174
1.838IlePro: 1.838 ± 0.27
1.021IleGln: 1.021 ± 0.183
2.221IleArg: 2.221 ± 0.244
1.66IleSer: 1.66 ± 0.23
2.323IleThr: 2.323 ± 0.338
1.787IleVal: 1.787 ± 0.227
0.306IleTrp: 0.306 ± 0.092
0.919IleTyr: 0.919 ± 0.174
0.0IleXaa: 0.0 ± 0.0
Lys
1.557LysAla: 1.557 ± 0.242
0.204LysCys: 0.204 ± 0.069
0.766LysAsp: 0.766 ± 0.125
0.46LysGlu: 0.46 ± 0.127
0.74LysPhe: 0.74 ± 0.136
0.638LysGly: 0.638 ± 0.1
0.511LysHis: 0.511 ± 0.12
0.664LysIle: 0.664 ± 0.14
0.536LysLys: 0.536 ± 0.143
1.404LysLeu: 1.404 ± 0.242
0.638LysMet: 0.638 ± 0.093
0.485LysAsn: 0.485 ± 0.098
0.996LysPro: 0.996 ± 0.159
0.689LysGln: 0.689 ± 0.166
2.145LysArg: 2.145 ± 0.266
0.894LysSer: 0.894 ± 0.134
1.43LysThr: 1.43 ± 0.172
1.174LysVal: 1.174 ± 0.187
0.077LysTrp: 0.077 ± 0.038
0.638LysTyr: 0.638 ± 0.143
0.0LysXaa: 0.0 ± 0.0
Leu
12.638LeuAla: 12.638 ± 0.881
2.247LeuCys: 2.247 ± 0.229
4.596LeuAsp: 4.596 ± 0.329
5.004LeuGlu: 5.004 ± 0.424
4.136LeuPhe: 4.136 ± 0.302
7.353LeuGly: 7.353 ± 0.495
2.221LeuHis: 2.221 ± 0.241
2.604LeuIle: 2.604 ± 0.217
1.481LeuLys: 1.481 ± 0.233
9.804LeuLeu: 9.804 ± 0.652
2.017LeuMet: 2.017 ± 0.279
2.043LeuAsn: 2.043 ± 0.305
5.974LeuPro: 5.974 ± 0.506
2.86LeuGln: 2.86 ± 0.268
9.37LeuArg: 9.37 ± 0.522
5.26LeuSer: 5.26 ± 0.476
5.234LeuThr: 5.234 ± 0.351
7.66LeuVal: 7.66 ± 0.587
1.277LeuTrp: 1.277 ± 0.232
2.655LeuTyr: 2.655 ± 0.274
0.0LeuXaa: 0.0 ± 0.0
Met
2.579MetAla: 2.579 ± 0.239
0.204MetCys: 0.204 ± 0.074
1.021MetAsp: 1.021 ± 0.152
0.766MetGlu: 0.766 ± 0.139
0.664MetPhe: 0.664 ± 0.106
1.379MetGly: 1.379 ± 0.176
0.434MetHis: 0.434 ± 0.095
0.409MetIle: 0.409 ± 0.105
0.357MetLys: 0.357 ± 0.095
1.583MetLeu: 1.583 ± 0.238
0.332MetMet: 0.332 ± 0.093
0.46MetAsn: 0.46 ± 0.089
0.613MetPro: 0.613 ± 0.15
0.485MetGln: 0.485 ± 0.151
1.634MetArg: 1.634 ± 0.175
1.174MetSer: 1.174 ± 0.177
0.919MetThr: 0.919 ± 0.138
0.868MetVal: 0.868 ± 0.115
0.23MetTrp: 0.23 ± 0.074
0.587MetTyr: 0.587 ± 0.127
0.0MetXaa: 0.0 ± 0.0
Asn
3.14AsnAla: 3.14 ± 0.296
0.357AsnCys: 0.357 ± 0.09
0.894AsnAsp: 0.894 ± 0.136
0.689AsnGlu: 0.689 ± 0.155
0.97AsnPhe: 0.97 ± 0.193
1.251AsnGly: 1.251 ± 0.239
0.485AsnHis: 0.485 ± 0.122
0.766AsnIle: 0.766 ± 0.155
0.485AsnLys: 0.485 ± 0.102
1.762AsnLeu: 1.762 ± 0.263
0.383AsnMet: 0.383 ± 0.101
0.945AsnAsn: 0.945 ± 0.206
1.813AsnPro: 1.813 ± 0.21
0.766AsnGln: 0.766 ± 0.127
1.353AsnArg: 1.353 ± 0.219
1.277AsnSer: 1.277 ± 0.175
2.145AsnThr: 2.145 ± 0.205
1.634AsnVal: 1.634 ± 0.182
0.179AsnTrp: 0.179 ± 0.059
0.817AsnTyr: 0.817 ± 0.161
0.0AsnXaa: 0.0 ± 0.0
Pro
10.902ProAla: 10.902 ± 0.825
1.2ProCys: 1.2 ± 0.169
4.468ProAsp: 4.468 ± 0.442
4.621ProGlu: 4.621 ± 0.35
1.583ProPhe: 1.583 ± 0.174
8.298ProGly: 8.298 ± 0.593
2.272ProHis: 2.272 ± 0.304
1.66ProIle: 1.66 ± 0.242
1.838ProLys: 1.838 ± 0.2
6.536ProLeu: 6.536 ± 0.515
1.047ProMet: 1.047 ± 0.181
1.608ProAsn: 1.608 ± 0.223
12.638ProPro: 12.638 ± 1.432
3.191ProGln: 3.191 ± 0.667
7.762ProArg: 7.762 ± 0.799
5.821ProSer: 5.821 ± 0.51
5.566ProThr: 5.566 ± 0.609
5.004ProVal: 5.004 ± 0.424
0.817ProTrp: 0.817 ± 0.139
1.43ProTyr: 1.43 ± 0.191
0.0ProXaa: 0.0 ± 0.0
Gln
3.396GlnAla: 3.396 ± 0.354
0.536GlnCys: 0.536 ± 0.093
1.174GlnAsp: 1.174 ± 0.194
1.2GlnGlu: 1.2 ± 0.171
1.021GlnPhe: 1.021 ± 0.163
1.711GlnGly: 1.711 ± 0.189
0.894GlnHis: 0.894 ± 0.177
1.174GlnIle: 1.174 ± 0.176
0.536GlnLys: 0.536 ± 0.141
3.498GlnLeu: 3.498 ± 0.331
0.511GlnMet: 0.511 ± 0.109
0.536GlnAsn: 0.536 ± 0.154
3.14GlnPro: 3.14 ± 0.625
1.353GlnGln: 1.353 ± 0.194
2.783GlnArg: 2.783 ± 0.257
1.404GlnSer: 1.404 ± 0.157
1.991GlnThr: 1.991 ± 0.195
1.481GlnVal: 1.481 ± 0.216
0.306GlnTrp: 0.306 ± 0.082
1.047GlnTyr: 1.047 ± 0.137
0.0GlnXaa: 0.0 ± 0.0
Arg
10.8ArgAla: 10.8 ± 0.709
1.481ArgCys: 1.481 ± 0.222
4.519ArgAsp: 4.519 ± 0.365
4.851ArgGlu: 4.851 ± 0.347
3.115ArgPhe: 3.115 ± 0.324
6.919ArgGly: 6.919 ± 0.452
2.604ArgHis: 2.604 ± 0.246
1.787ArgIle: 1.787 ± 0.217
1.098ArgLys: 1.098 ± 0.181
8.4ArgLeu: 8.4 ± 0.363
1.404ArgMet: 1.404 ± 0.197
1.583ArgAsn: 1.583 ± 0.183
7.506ArgPro: 7.506 ± 0.502
2.477ArgGln: 2.477 ± 0.257
9.447ArgArg: 9.447 ± 0.74
4.902ArgSer: 4.902 ± 0.409
4.391ArgThr: 4.391 ± 0.402
5.77ArgVal: 5.77 ± 0.476
0.791ArgTrp: 0.791 ± 0.146
2.247ArgTyr: 2.247 ± 0.248
0.0ArgXaa: 0.0 ± 0.0
Ser
7.711SerAla: 7.711 ± 0.523
1.021SerCys: 1.021 ± 0.203
2.885SerAsp: 2.885 ± 0.331
3.14SerGlu: 3.14 ± 0.28
1.711SerPhe: 1.711 ± 0.23
5.489SerGly: 5.489 ± 0.53
1.711SerHis: 1.711 ± 0.189
1.481SerIle: 1.481 ± 0.223
0.791SerLys: 0.791 ± 0.151
6.077SerLeu: 6.077 ± 0.451
0.945SerMet: 0.945 ± 0.188
0.868SerAsn: 0.868 ± 0.175
6.562SerPro: 6.562 ± 0.533
1.915SerGln: 1.915 ± 0.232
4.545SerArg: 4.545 ± 0.388
5.872SerSer: 5.872 ± 0.686
3.447SerThr: 3.447 ± 0.336
4.468SerVal: 4.468 ± 0.376
0.664SerTrp: 0.664 ± 0.175
0.996SerTyr: 0.996 ± 0.189
0.0SerXaa: 0.0 ± 0.0
Thr
7.225ThrAla: 7.225 ± 0.395
0.945ThrCys: 0.945 ± 0.145
2.757ThrAsp: 2.757 ± 0.241
2.681ThrGlu: 2.681 ± 0.284
1.966ThrPhe: 1.966 ± 0.237
3.855ThrGly: 3.855 ± 0.286
2.068ThrHis: 2.068 ± 0.238
2.094ThrIle: 2.094 ± 0.237
1.226ThrLys: 1.226 ± 0.187
4.902ThrLeu: 4.902 ± 0.382
0.817ThrMet: 0.817 ± 0.146
1.685ThrAsn: 1.685 ± 0.282
5.872ThrPro: 5.872 ± 0.549
1.966ThrGln: 1.966 ± 0.23
5.081ThrArg: 5.081 ± 0.308
3.319ThrSer: 3.319 ± 0.307
4.8ThrThr: 4.8 ± 0.355
3.217ThrVal: 3.217 ± 0.294
0.843ThrTrp: 0.843 ± 0.127
1.685ThrTyr: 1.685 ± 0.219
0.0ThrXaa: 0.0 ± 0.0
Val
8.323ValAla: 8.323 ± 0.489
1.583ValCys: 1.583 ± 0.227
3.243ValAsp: 3.243 ± 0.27
2.808ValGlu: 2.808 ± 0.224
2.962ValPhe: 2.962 ± 0.398
5.004ValGly: 5.004 ± 0.341
1.711ValHis: 1.711 ± 0.179
2.426ValIle: 2.426 ± 0.289
1.251ValLys: 1.251 ± 0.181
7.404ValLeu: 7.404 ± 0.383
1.226ValMet: 1.226 ± 0.164
1.889ValAsn: 1.889 ± 0.281
5.847ValPro: 5.847 ± 0.447
1.991ValGln: 1.991 ± 0.222
6.0ValArg: 6.0 ± 0.38
4.902ValSer: 4.902 ± 0.414
3.83ValThr: 3.83 ± 0.284
6.383ValVal: 6.383 ± 0.537
0.868ValTrp: 0.868 ± 0.148
2.094ValTyr: 2.094 ± 0.255
0.0ValXaa: 0.0 ± 0.0
Trp
1.43TrpAla: 1.43 ± 0.228
0.153TrpCys: 0.153 ± 0.061
0.511TrpAsp: 0.511 ± 0.084
0.511TrpGlu: 0.511 ± 0.114
0.409TrpPhe: 0.409 ± 0.118
1.149TrpGly: 1.149 ± 0.183
0.306TrpHis: 0.306 ± 0.108
0.357TrpIle: 0.357 ± 0.097
0.204TrpLys: 0.204 ± 0.073
1.302TrpLeu: 1.302 ± 0.2
0.306TrpMet: 0.306 ± 0.11
0.179TrpAsn: 0.179 ± 0.058
0.613TrpPro: 0.613 ± 0.13
0.204TrpGln: 0.204 ± 0.077
1.149TrpArg: 1.149 ± 0.198
0.664TrpSer: 0.664 ± 0.128
0.791TrpThr: 0.791 ± 0.151
0.766TrpVal: 0.766 ± 0.154
0.255TrpTrp: 0.255 ± 0.078
0.255TrpTyr: 0.255 ± 0.084
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.089TyrAla: 3.089 ± 0.317
0.562TyrCys: 0.562 ± 0.11
1.353TyrAsp: 1.353 ± 0.224
0.791TyrGlu: 0.791 ± 0.173
0.868TyrPhe: 0.868 ± 0.17
1.762TyrGly: 1.762 ± 0.21
0.613TyrHis: 0.613 ± 0.131
0.945TyrIle: 0.945 ± 0.154
0.409TyrLys: 0.409 ± 0.125
2.757TyrLeu: 2.757 ± 0.268
0.511TyrMet: 0.511 ± 0.107
0.766TyrAsn: 0.766 ± 0.145
1.711TyrPro: 1.711 ± 0.27
0.664TyrGln: 0.664 ± 0.111
1.711TyrArg: 1.711 ± 0.222
1.379TyrSer: 1.379 ± 0.208
1.2TyrThr: 1.2 ± 0.179
2.579TyrVal: 2.579 ± 0.215
0.357TyrTrp: 0.357 ± 0.093
1.277TyrTyr: 1.277 ± 0.208
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 74 proteins (39168 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski