Amino acid dipepetide frequency for Hubei tombus-like virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.411AlaAla: 12.411 ± 7.796
1.773AlaCys: 1.773 ± 0.834
2.66AlaAsp: 2.66 ± 1.267
1.773AlaGlu: 1.773 ± 1.422
1.773AlaPhe: 1.773 ± 0.717
6.206AlaGly: 6.206 ± 2.664
1.773AlaHis: 1.773 ± 1.505
2.66AlaIle: 2.66 ± 1.195
6.206AlaLys: 6.206 ± 3.013
5.319AlaLeu: 5.319 ± 1.364
0.887AlaMet: 0.887 ± 0.711
1.773AlaAsn: 1.773 ± 1.422
7.979AlaPro: 7.979 ± 2.304
1.773AlaGln: 1.773 ± 0.834
9.752AlaArg: 9.752 ± 1.678
2.66AlaSer: 2.66 ± 1.43
7.979AlaThr: 7.979 ± 2.525
4.433AlaVal: 4.433 ± 0.957
0.887AlaTrp: 0.887 ± 0.753
0.887AlaTyr: 0.887 ± 0.711
0.0AlaXaa: 0.0 ± 0.0
Cys
0.887CysAla: 0.887 ± 0.711
0.0CysCys: 0.0 ± 0.0
0.887CysAsp: 0.887 ± 0.753
0.887CysGlu: 0.887 ± 0.753
0.887CysPhe: 0.887 ± 0.753
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.887CysIle: 0.887 ± 0.753
0.0CysLys: 0.0 ± 0.0
0.887CysLeu: 0.887 ± 0.753
1.773CysMet: 1.773 ± 1.505
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.773CysGln: 1.773 ± 0.834
0.887CysArg: 0.887 ± 0.753
2.66CysSer: 2.66 ± 0.125
2.66CysThr: 2.66 ± 1.321
0.0CysVal: 0.0 ± 0.0
0.887CysTrp: 0.887 ± 0.781
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
0.887AspAla: 0.887 ± 0.753
0.0AspCys: 0.0 ± 0.0
0.887AspAsp: 0.887 ± 0.753
0.887AspGlu: 0.887 ± 0.753
1.773AspPhe: 1.773 ± 1.505
2.66AspGly: 2.66 ± 2.258
2.66AspHis: 2.66 ± 1.267
0.887AspIle: 0.887 ± 0.753
4.433AspLys: 4.433 ± 1.3
3.546AspLeu: 3.546 ± 1.399
0.887AspMet: 0.887 ± 0.753
0.887AspAsn: 0.887 ± 0.711
4.433AspPro: 4.433 ± 0.702
0.887AspGln: 0.887 ± 0.753
4.433AspArg: 4.433 ± 1.3
1.773AspSer: 1.773 ± 0.7
1.773AspThr: 1.773 ± 0.717
3.546AspVal: 3.546 ± 1.667
0.887AspTrp: 0.887 ± 0.781
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
7.092GluAla: 7.092 ± 0.709
0.887GluCys: 0.887 ± 0.711
2.66GluAsp: 2.66 ± 1.195
4.433GluGlu: 4.433 ± 0.632
2.66GluPhe: 2.66 ± 1.267
2.66GluGly: 2.66 ± 0.125
0.887GluHis: 0.887 ± 0.753
2.66GluIle: 2.66 ± 1.383
0.887GluLys: 0.887 ± 0.753
7.092GluLeu: 7.092 ± 2.712
3.546GluMet: 3.546 ± 0.589
0.0GluAsn: 0.0 ± 0.0
0.887GluPro: 0.887 ± 0.753
2.66GluGln: 2.66 ± 1.193
1.773GluArg: 1.773 ± 0.7
1.773GluSer: 1.773 ± 1.422
0.887GluThr: 0.887 ± 0.753
5.319GluVal: 5.319 ± 1.077
0.0GluTrp: 0.0 ± 0.0
1.773GluTyr: 1.773 ± 0.834
0.0GluXaa: 0.0 ± 0.0
Phe
3.546PheAla: 3.546 ± 0.806
0.887PheCys: 0.887 ± 0.753
3.546PheAsp: 3.546 ± 1.964
0.0PheGlu: 0.0 ± 0.0
0.887PhePhe: 0.887 ± 0.753
2.66PheGly: 2.66 ± 2.258
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
1.773PheLys: 1.773 ± 0.7
2.66PheLeu: 2.66 ± 1.193
0.0PheMet: 0.0 ± 0.0
0.887PheAsn: 0.887 ± 0.781
1.773PhePro: 1.773 ± 0.834
2.66PheGln: 2.66 ± 1.383
1.773PheArg: 1.773 ± 0.834
0.887PheSer: 0.887 ± 0.711
2.66PheThr: 2.66 ± 0.125
0.887PheVal: 0.887 ± 0.781
0.0PheTrp: 0.0 ± 0.0
1.773PheTyr: 1.773 ± 1.505
0.0PheXaa: 0.0 ± 0.0
Gly
3.546GlyAla: 3.546 ± 0.589
0.887GlyCys: 0.887 ± 0.781
6.206GlyAsp: 6.206 ± 1.976
2.66GlyGlu: 2.66 ± 0.125
0.887GlyPhe: 0.887 ± 0.781
3.546GlyGly: 3.546 ± 1.831
1.773GlyHis: 1.773 ± 1.422
2.66GlyIle: 2.66 ± 1.43
6.206GlyLys: 6.206 ± 3.013
7.979GlyLeu: 7.979 ± 1.034
1.773GlyMet: 1.773 ± 1.505
7.092GlyAsn: 7.092 ± 1.87
2.66GlyPro: 2.66 ± 2.133
4.433GlyGln: 4.433 ± 1.653
3.546GlyArg: 3.546 ± 0.589
7.979GlySer: 7.979 ± 2.129
8.865GlyThr: 8.865 ± 2.373
7.092GlyVal: 7.092 ± 1.08
2.66GlyTrp: 2.66 ± 0.125
1.773GlyTyr: 1.773 ± 0.834
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
2.66HisPhe: 2.66 ± 1.267
2.66HisGly: 2.66 ± 1.193
0.0HisHis: 0.0 ± 0.0
0.887HisIle: 0.887 ± 0.753
0.887HisLys: 0.887 ± 0.753
0.887HisLeu: 0.887 ± 0.711
0.0HisMet: 0.0 ± 0.0
0.887HisAsn: 0.887 ± 0.753
2.66HisPro: 2.66 ± 1.193
0.887HisGln: 0.887 ± 0.711
1.773HisArg: 1.773 ± 1.422
0.887HisSer: 0.887 ± 0.753
0.887HisThr: 0.887 ± 0.711
1.773HisVal: 1.773 ± 0.834
0.0HisTrp: 0.0 ± 0.0
0.887HisTyr: 0.887 ± 0.753
0.0HisXaa: 0.0 ± 0.0
Ile
2.66IleAla: 2.66 ± 1.267
0.887IleCys: 0.887 ± 0.753
1.773IleAsp: 1.773 ± 0.717
3.546IleGlu: 3.546 ± 2.065
2.66IlePhe: 2.66 ± 0.125
1.773IleGly: 1.773 ± 0.834
0.887IleHis: 0.887 ± 0.711
2.66IleIle: 2.66 ± 1.193
0.0IleLys: 0.0 ± 0.0
0.887IleLeu: 0.887 ± 0.781
0.0IleMet: 0.0 ± 0.0
0.887IleAsn: 0.887 ± 0.753
0.887IlePro: 0.887 ± 0.781
0.887IleGln: 0.887 ± 0.753
2.66IleArg: 2.66 ± 1.193
3.546IleSer: 3.546 ± 1.667
1.773IleThr: 1.773 ± 1.563
1.773IleVal: 1.773 ± 0.834
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.546LysAla: 3.546 ± 0.806
0.887LysCys: 0.887 ± 0.753
1.773LysAsp: 1.773 ± 0.7
6.206LysGlu: 6.206 ± 3.013
4.433LysPhe: 4.433 ± 2.691
4.433LysGly: 4.433 ± 1.904
2.66LysHis: 2.66 ± 1.193
0.887LysIle: 0.887 ± 0.711
4.433LysLys: 4.433 ± 2.514
5.319LysLeu: 5.319 ± 2.099
0.0LysMet: 0.0 ± 0.0
1.773LysAsn: 1.773 ± 1.422
2.66LysPro: 2.66 ± 1.195
5.319LysGln: 5.319 ± 3.208
5.319LysArg: 5.319 ± 3.208
7.092LysSer: 7.092 ± 3.433
1.773LysThr: 1.773 ± 0.717
2.66LysVal: 2.66 ± 1.193
0.0LysTrp: 0.0 ± 0.0
1.773LysTyr: 1.773 ± 1.505
0.0LysXaa: 0.0 ± 0.0
Leu
2.66LeuAla: 2.66 ± 1.383
1.773LeuCys: 1.773 ± 0.7
1.773LeuAsp: 1.773 ± 0.7
6.206LeuGlu: 6.206 ± 1.712
0.0LeuPhe: 0.0 ± 0.0
9.752LeuGly: 9.752 ± 1.204
0.887LeuHis: 0.887 ± 0.753
2.66LeuIle: 2.66 ± 1.43
3.546LeuLys: 3.546 ± 1.399
6.206LeuLeu: 6.206 ± 1.327
2.66LeuMet: 2.66 ± 1.195
3.546LeuAsn: 3.546 ± 3.126
4.433LeuPro: 4.433 ± 1.555
0.887LeuGln: 0.887 ± 0.711
11.525LeuArg: 11.525 ± 1.21
5.319LeuSer: 5.319 ± 1.259
3.546LeuThr: 3.546 ± 2.048
4.433LeuVal: 4.433 ± 1.653
0.887LeuTrp: 0.887 ± 0.753
1.773LeuTyr: 1.773 ± 0.834
0.0LeuXaa: 0.0 ± 0.0
Met
1.773MetAla: 1.773 ± 1.505
0.0MetCys: 0.0 ± 0.0
0.887MetAsp: 0.887 ± 0.753
3.546MetGlu: 3.546 ± 0.806
1.773MetPhe: 1.773 ± 1.505
1.773MetGly: 1.773 ± 0.834
0.887MetHis: 0.887 ± 0.711
0.887MetIle: 0.887 ± 0.753
0.0MetLys: 0.0 ± 0.0
1.773MetLeu: 1.773 ± 0.834
0.0MetMet: 0.0 ± 0.0
0.887MetAsn: 0.887 ± 0.711
2.66MetPro: 2.66 ± 1.195
1.773MetGln: 1.773 ± 0.834
0.887MetArg: 0.887 ± 0.711
0.887MetSer: 0.887 ± 0.753
0.887MetThr: 0.887 ± 0.781
1.773MetVal: 1.773 ± 1.505
0.0MetTrp: 0.0 ± 0.0
1.773MetTyr: 1.773 ± 0.717
0.0MetXaa: 0.0 ± 0.0
Asn
3.546AsnAla: 3.546 ± 2.048
0.887AsnCys: 0.887 ± 0.781
0.887AsnAsp: 0.887 ± 0.711
0.0AsnGlu: 0.0 ± 0.0
0.0AsnPhe: 0.0 ± 0.0
2.66AsnGly: 2.66 ± 0.125
0.887AsnHis: 0.887 ± 0.753
0.0AsnIle: 0.0 ± 0.0
8.865AsnLys: 8.865 ± 3.782
1.773AsnLeu: 1.773 ± 0.834
0.887AsnMet: 0.887 ± 0.781
4.433AsnAsn: 4.433 ± 1.653
3.546AsnPro: 3.546 ± 2.065
1.773AsnGln: 1.773 ± 0.717
1.773AsnArg: 1.773 ± 0.717
3.546AsnSer: 3.546 ± 0.873
2.66AsnThr: 2.66 ± 0.125
3.546AsnVal: 3.546 ± 1.434
0.887AsnTrp: 0.887 ± 0.781
0.887AsnTyr: 0.887 ± 0.753
0.0AsnXaa: 0.0 ± 0.0
Pro
7.979ProAla: 7.979 ± 4.143
0.0ProCys: 0.0 ± 0.0
3.546ProAsp: 3.546 ± 0.873
3.546ProGlu: 3.546 ± 0.873
0.887ProPhe: 0.887 ± 0.781
7.979ProGly: 7.979 ± 3.363
0.0ProHis: 0.0 ± 0.0
2.66ProIle: 2.66 ± 1.267
3.546ProLys: 3.546 ± 1.399
3.546ProLeu: 3.546 ± 3.126
0.0ProMet: 0.0 ± 0.0
1.773ProAsn: 1.773 ± 1.422
5.319ProPro: 5.319 ± 4.266
5.319ProGln: 5.319 ± 2.011
2.66ProArg: 2.66 ± 0.125
3.546ProSer: 3.546 ± 1.434
3.546ProThr: 3.546 ± 2.065
5.319ProVal: 5.319 ± 2.433
1.773ProTrp: 1.773 ± 0.834
0.887ProTyr: 0.887 ± 0.753
0.0ProXaa: 0.0 ± 0.0
Gln
2.66GlnAla: 2.66 ± 1.195
0.887GlnCys: 0.887 ± 0.753
1.773GlnAsp: 1.773 ± 1.505
1.773GlnGlu: 1.773 ± 1.422
2.66GlnPhe: 2.66 ± 0.125
2.66GlnGly: 2.66 ± 1.195
1.773GlnHis: 1.773 ± 1.505
1.773GlnIle: 1.773 ± 0.834
0.887GlnLys: 0.887 ± 0.711
3.546GlnLeu: 3.546 ± 0.873
0.0GlnMet: 0.0 ± 0.0
2.66GlnAsn: 2.66 ± 1.43
0.887GlnPro: 0.887 ± 0.711
1.773GlnGln: 1.773 ± 0.7
1.773GlnArg: 1.773 ± 0.834
6.206GlnSer: 6.206 ± 2.522
1.773GlnThr: 1.773 ± 0.834
2.66GlnVal: 2.66 ± 0.125
0.887GlnTrp: 0.887 ± 0.711
1.773GlnTyr: 1.773 ± 0.7
0.0GlnXaa: 0.0 ± 0.0
Arg
8.865ArgAla: 8.865 ± 0.353
2.66ArgCys: 2.66 ± 1.267
0.887ArgAsp: 0.887 ± 0.711
2.66ArgGlu: 2.66 ± 1.267
0.0ArgPhe: 0.0 ± 0.0
7.979ArgGly: 7.979 ± 0.374
0.887ArgHis: 0.887 ± 0.711
2.66ArgIle: 2.66 ± 1.43
4.433ArgLys: 4.433 ± 2.508
9.752ArgLeu: 9.752 ± 2.937
2.66ArgMet: 2.66 ± 1.311
6.206ArgAsn: 6.206 ± 1.976
1.773ArgPro: 1.773 ± 0.7
0.887ArgGln: 0.887 ± 0.781
2.66ArgArg: 2.66 ± 1.321
4.433ArgSer: 4.433 ± 0.702
11.525ArgThr: 11.525 ± 2.478
5.319ArgVal: 5.319 ± 2.39
0.887ArgTrp: 0.887 ± 0.711
2.66ArgTyr: 2.66 ± 1.43
0.0ArgXaa: 0.0 ± 0.0
Ser
6.206SerAla: 6.206 ± 2.522
0.0SerCys: 0.0 ± 0.0
1.773SerAsp: 1.773 ± 1.563
2.66SerGlu: 2.66 ± 2.344
0.0SerPhe: 0.0 ± 0.0
9.752SerGly: 9.752 ± 2.288
0.887SerHis: 0.887 ± 0.711
0.887SerIle: 0.887 ± 0.711
6.206SerLys: 6.206 ± 2.489
4.433SerLeu: 4.433 ± 1.3
2.66SerMet: 2.66 ± 1.14
3.546SerAsn: 3.546 ± 1.434
2.66SerPro: 2.66 ± 1.321
0.887SerGln: 0.887 ± 0.711
5.319SerArg: 5.319 ± 1.111
6.206SerSer: 6.206 ± 3.01
7.979SerThr: 7.979 ± 2.129
7.979SerVal: 7.979 ± 2.979
0.887SerTrp: 0.887 ± 0.753
2.66SerTyr: 2.66 ± 0.125
0.0SerXaa: 0.0 ± 0.0
Thr
5.319ThrAla: 5.319 ± 2.641
1.773ThrCys: 1.773 ± 1.563
1.773ThrAsp: 1.773 ± 0.7
1.773ThrGlu: 1.773 ± 1.422
2.66ThrPhe: 2.66 ± 0.125
8.865ThrGly: 8.865 ± 1.627
0.887ThrHis: 0.887 ± 0.711
0.887ThrIle: 0.887 ± 0.753
3.546ThrLys: 3.546 ± 3.011
4.433ThrLeu: 4.433 ± 1.653
2.66ThrMet: 2.66 ± 1.941
2.66ThrAsn: 2.66 ± 1.321
8.865ThrPro: 8.865 ± 2.175
1.773ThrGln: 1.773 ± 0.717
7.979ThrArg: 7.979 ± 2.624
5.319ThrSer: 5.319 ± 2.151
9.752ThrThr: 9.752 ± 4.599
5.319ThrVal: 5.319 ± 1.364
0.887ThrTrp: 0.887 ± 0.781
2.66ThrTyr: 2.66 ± 1.43
0.0ThrXaa: 0.0 ± 0.0
Val
3.546ValAla: 3.546 ± 3.126
0.0ValCys: 0.0 ± 0.0
4.433ValAsp: 4.433 ± 1.555
7.092ValGlu: 7.092 ± 3.811
2.66ValPhe: 2.66 ± 1.383
5.319ValGly: 5.319 ± 0.25
0.0ValHis: 0.0 ± 0.0
1.773ValIle: 1.773 ± 1.563
3.546ValLys: 3.546 ± 2.844
1.773ValLeu: 1.773 ± 0.717
1.773ValMet: 1.773 ± 0.834
2.66ValAsn: 2.66 ± 2.344
7.979ValPro: 7.979 ± 2.681
3.546ValGln: 3.546 ± 1.667
8.865ValArg: 8.865 ± 2.468
6.206ValSer: 6.206 ± 2.109
6.206ValThr: 6.206 ± 1.79
1.773ValVal: 1.773 ± 0.834
0.887ValTrp: 0.887 ± 0.781
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.66TrpAla: 2.66 ± 1.267
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.887TrpGlu: 0.887 ± 0.753
0.0TrpPhe: 0.0 ± 0.0
0.887TrpGly: 0.887 ± 0.753
0.0TrpHis: 0.0 ± 0.0
0.887TrpIle: 0.887 ± 0.711
0.887TrpLys: 0.887 ± 0.781
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.887TrpAsn: 0.887 ± 0.781
0.887TrpPro: 0.887 ± 0.781
0.887TrpGln: 0.887 ± 0.781
0.887TrpArg: 0.887 ± 0.753
0.887TrpSer: 0.887 ± 0.711
0.887TrpThr: 0.887 ± 0.781
2.66TrpVal: 2.66 ± 2.344
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.773TyrAla: 1.773 ± 0.7
1.773TyrCys: 1.773 ± 1.505
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.887TyrHis: 0.887 ± 0.781
0.887TyrIle: 0.887 ± 0.753
2.66TyrLys: 2.66 ± 1.267
2.66TyrLeu: 2.66 ± 1.383
1.773TyrMet: 1.773 ± 1.505
0.0TyrAsn: 0.0 ± 0.0
0.887TyrPro: 0.887 ± 0.781
0.0TyrGln: 0.0 ± 0.0
3.546TyrArg: 3.546 ± 2.065
1.773TyrSer: 1.773 ± 0.717
2.66TyrThr: 2.66 ± 1.321
1.773TyrVal: 1.773 ± 0.834
0.887TyrTrp: 0.887 ± 0.781
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1129 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski