Amino acid dipepetide frequency for Cucumber mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.506AlaAla: 9.506 ± 0.758
0.92AlaCys: 0.92 ± 0.235
2.76AlaAsp: 2.76 ± 1.2
2.453AlaGlu: 2.453 ± 0.387
2.453AlaPhe: 2.453 ± 0.387
6.746AlaGly: 6.746 ± 1.535
0.613AlaHis: 0.613 ± 0.151
3.373AlaIle: 3.373 ± 0.832
4.293AlaLys: 4.293 ± 1.254
7.973AlaLeu: 7.973 ± 0.842
0.92AlaMet: 0.92 ± 0.283
2.76AlaAsn: 2.76 ± 0.706
1.227AlaPro: 1.227 ± 0.301
1.533AlaGln: 1.533 ± 0.469
3.067AlaArg: 3.067 ± 0.662
1.84AlaSer: 1.84 ± 0.258
4.906AlaThr: 4.906 ± 0.581
4.906AlaVal: 4.906 ± 0.182
0.0AlaTrp: 0.0 ± 0.0
2.147AlaTyr: 2.147 ± 0.427
0.307AlaXaa: 0.307 ± 0.188
Cys
0.0CysAla: 0.0 ± 0.0
0.613CysCys: 0.613 ± 0.151
1.533CysAsp: 1.533 ± 0.347
1.84CysGlu: 1.84 ± 0.452
0.0CysPhe: 0.0 ± 0.0
1.533CysGly: 1.533 ± 0.577
0.0CysHis: 0.0 ± 0.0
0.613CysIle: 0.613 ± 0.151
0.613CysLys: 0.613 ± 0.467
1.533CysLeu: 1.533 ± 0.347
0.0CysMet: 0.0 ± 0.0
0.613CysAsn: 0.613 ± 0.151
1.227CysPro: 1.227 ± 0.301
0.0CysGln: 0.0 ± 0.0
0.307CysArg: 0.307 ± 0.188
1.533CysSer: 1.533 ± 0.331
1.84CysThr: 1.84 ± 0.452
1.533CysVal: 1.533 ± 0.577
0.0CysTrp: 0.0 ± 0.0
0.613CysTyr: 0.613 ± 0.151
0.0CysXaa: 0.0 ± 0.0
Asp
6.133AspAla: 6.133 ± 0.621
1.227AspCys: 1.227 ± 0.301
4.6AspAsp: 4.6 ± 0.202
4.6AspGlu: 4.6 ± 1.062
4.293AspPhe: 4.293 ± 1.039
3.067AspGly: 3.067 ± 0.524
1.227AspHis: 1.227 ± 0.346
3.067AspIle: 3.067 ± 0.695
4.906AspLys: 4.906 ± 0.485
3.987AspLeu: 3.987 ± 0.613
0.613AspMet: 0.613 ± 0.417
3.067AspAsn: 3.067 ± 0.423
0.92AspPro: 0.92 ± 0.597
1.84AspGln: 1.84 ± 0.452
3.067AspArg: 3.067 ± 0.311
6.133AspSer: 6.133 ± 2.351
4.906AspThr: 4.906 ± 0.501
6.746AspVal: 6.746 ± 1.276
0.307AspTrp: 0.307 ± 0.188
2.147AspTyr: 2.147 ± 0.323
0.0AspXaa: 0.0 ± 0.0
Glu
3.067GluAla: 3.067 ± 0.423
0.307GluCys: 0.307 ± 0.188
1.533GluAsp: 1.533 ± 0.347
1.533GluGlu: 1.533 ± 0.347
3.373GluPhe: 3.373 ± 0.832
3.067GluGly: 3.067 ± 0.662
1.227GluHis: 1.227 ± 0.301
2.76GluIle: 2.76 ± 0.381
5.213GluLys: 5.213 ± 1.211
6.133GluLeu: 6.133 ± 0.983
0.92GluMet: 0.92 ± 0.235
1.227GluAsn: 1.227 ± 0.399
1.84GluPro: 1.84 ± 0.452
0.307GluGln: 0.307 ± 0.188
2.147GluArg: 2.147 ± 0.308
5.213GluSer: 5.213 ± 1.072
2.147GluThr: 2.147 ± 0.481
4.293GluVal: 4.293 ± 0.612
0.92GluTrp: 0.92 ± 0.235
2.76GluTyr: 2.76 ± 0.29
0.0GluXaa: 0.0 ± 0.0
Phe
3.987PheAla: 3.987 ± 0.914
1.227PheCys: 1.227 ± 0.399
4.906PheAsp: 4.906 ± 0.485
1.84PheGlu: 1.84 ± 0.407
4.293PhePhe: 4.293 ± 0.412
2.453PheGly: 2.453 ± 0.574
1.533PheHis: 1.533 ± 0.347
3.373PheIle: 3.373 ± 0.589
3.373PheLys: 3.373 ± 0.437
3.987PheLeu: 3.987 ± 0.801
1.227PheMet: 1.227 ± 0.301
0.92PheAsn: 0.92 ± 0.502
2.453PhePro: 2.453 ± 0.387
3.68PheGln: 3.68 ± 0.522
2.453PheArg: 2.453 ± 0.574
10.426PheSer: 10.426 ± 1.088
3.987PheThr: 3.987 ± 0.663
2.453PheVal: 2.453 ± 0.693
0.0PheTrp: 0.0 ± 0.0
2.453PheTyr: 2.453 ± 0.953
0.0PheXaa: 0.0 ± 0.0
Gly
2.453GlyAla: 2.453 ± 0.243
1.533GlyCys: 1.533 ± 0.388
3.067GlyAsp: 3.067 ± 0.695
3.373GlyGlu: 3.373 ± 0.562
0.613GlyPhe: 0.613 ± 0.578
2.147GlyGly: 2.147 ± 0.724
0.307GlyHis: 0.307 ± 0.188
1.533GlyIle: 1.533 ± 0.347
3.987GlyLys: 3.987 ± 0.446
8.893GlyLeu: 8.893 ± 0.455
0.0GlyMet: 0.0 ± 0.0
2.453GlyAsn: 2.453 ± 0.953
2.453GlyPro: 2.453 ± 0.243
0.613GlyGln: 0.613 ± 0.376
1.533GlyArg: 1.533 ± 0.469
3.373GlySer: 3.373 ± 0.907
2.453GlyThr: 2.453 ± 0.693
5.52GlyVal: 5.52 ± 2.027
0.613GlyTrp: 0.613 ± 0.151
1.533GlyTyr: 1.533 ± 0.347
0.0GlyXaa: 0.0 ± 0.0
His
0.307HisAla: 0.307 ± 0.188
0.613HisCys: 0.613 ± 0.151
1.227HisAsp: 1.227 ± 0.301
0.92HisGlu: 0.92 ± 0.235
1.533HisPhe: 1.533 ± 0.347
0.0HisGly: 0.0 ± 0.0
0.613HisHis: 0.613 ± 0.376
1.227HisIle: 1.227 ± 0.301
1.84HisLys: 1.84 ± 0.258
1.84HisLeu: 1.84 ± 0.471
0.92HisMet: 0.92 ± 0.235
0.0HisAsn: 0.0 ± 0.0
0.613HisPro: 0.613 ± 0.467
0.613HisGln: 0.613 ± 0.151
0.92HisArg: 0.92 ± 0.235
3.373HisSer: 3.373 ± 0.563
2.147HisThr: 2.147 ± 0.481
1.84HisVal: 1.84 ± 0.452
0.0HisTrp: 0.0 ± 0.0
0.613HisTyr: 0.613 ± 0.151
0.0HisXaa: 0.0 ± 0.0
Ile
3.373IleAla: 3.373 ± 0.563
1.533IleCys: 1.533 ± 0.347
3.373IleAsp: 3.373 ± 0.806
1.84IleGlu: 1.84 ± 0.407
2.453IlePhe: 2.453 ± 0.387
3.68IleGly: 3.68 ± 0.826
1.84IleHis: 1.84 ± 0.471
0.92IleIle: 0.92 ± 0.502
2.453IleLys: 2.453 ± 1.275
1.533IleLeu: 1.533 ± 0.388
0.613IleMet: 0.613 ± 0.151
3.68IleAsn: 3.68 ± 0.504
3.373IlePro: 3.373 ± 0.563
1.84IleGln: 1.84 ± 0.471
3.067IleArg: 3.067 ± 0.753
3.373IleSer: 3.373 ± 0.563
3.987IleThr: 3.987 ± 1.297
5.52IleVal: 5.52 ± 0.837
0.307IleTrp: 0.307 ± 0.188
0.92IleTyr: 0.92 ± 0.235
0.0IleXaa: 0.0 ± 0.0
Lys
7.053LysAla: 7.053 ± 0.333
0.0LysCys: 0.0 ± 0.0
4.293LysAsp: 4.293 ± 0.647
2.453LysGlu: 2.453 ± 0.603
5.826LysPhe: 5.826 ± 0.858
3.68LysGly: 3.68 ± 0.424
0.307LysHis: 0.307 ± 0.506
3.067LysIle: 3.067 ± 0.753
3.373LysLys: 3.373 ± 0.563
3.68LysLeu: 3.68 ± 1.004
0.92LysMet: 0.92 ± 0.451
3.987LysAsn: 3.987 ± 0.919
2.76LysPro: 2.76 ± 0.381
1.533LysGln: 1.533 ± 0.347
5.52LysArg: 5.52 ± 0.895
6.44LysSer: 6.44 ± 1.189
2.147LysThr: 2.147 ± 0.627
5.213LysVal: 5.213 ± 0.872
0.0LysTrp: 0.0 ± 0.0
1.84LysTyr: 1.84 ± 0.502
0.0LysXaa: 0.0 ± 0.0
Leu
3.987LeuAla: 3.987 ± 0.919
1.227LeuCys: 1.227 ± 0.301
6.133LeuAsp: 6.133 ± 1.282
5.213LeuGlu: 5.213 ± 0.993
5.213LeuPhe: 5.213 ± 0.742
3.067LeuGly: 3.067 ± 0.641
2.147LeuHis: 2.147 ± 0.481
4.293LeuIle: 4.293 ± 0.585
5.213LeuLys: 5.213 ± 0.811
6.133LeuLeu: 6.133 ± 1.36
3.067LeuMet: 3.067 ± 0.695
4.906LeuAsn: 4.906 ± 0.735
3.68LeuPro: 3.68 ± 0.684
2.453LeuGln: 2.453 ± 0.52
5.213LeuArg: 5.213 ± 0.445
8.586LeuSer: 8.586 ± 1.256
6.133LeuThr: 6.133 ± 0.227
8.893LeuVal: 8.893 ± 0.431
0.613LeuTrp: 0.613 ± 0.151
1.533LeuTyr: 1.533 ± 0.347
0.0LeuXaa: 0.0 ± 0.0
Met
1.227MetAla: 1.227 ± 0.477
0.0MetCys: 0.0 ± 0.0
1.84MetAsp: 1.84 ± 0.471
0.92MetGlu: 0.92 ± 0.4
0.0MetPhe: 0.0 ± 0.0
0.613MetGly: 0.613 ± 0.151
0.0MetHis: 0.0 ± 0.0
1.227MetIle: 1.227 ± 0.399
0.307MetLys: 0.307 ± 0.188
1.84MetLeu: 1.84 ± 0.471
1.84MetMet: 1.84 ± 0.452
2.76MetAsn: 2.76 ± 0.623
0.307MetPro: 0.307 ± 0.188
0.92MetGln: 0.92 ± 0.235
0.613MetArg: 0.613 ± 0.151
0.307MetSer: 0.307 ± 0.506
0.0MetThr: 0.0 ± 0.0
3.067MetVal: 3.067 ± 0.753
0.307MetTrp: 0.307 ± 0.188
1.227MetTyr: 1.227 ± 0.301
0.0MetXaa: 0.0 ± 0.0
Asn
1.84AsnAla: 1.84 ± 0.407
0.613AsnCys: 0.613 ± 0.151
1.227AsnAsp: 1.227 ± 0.399
3.067AsnGlu: 3.067 ± 0.695
5.52AsnPhe: 5.52 ± 0.58
1.84AsnGly: 1.84 ± 1.055
1.227AsnHis: 1.227 ± 0.346
3.68AsnIle: 3.68 ± 0.46
2.147AsnLys: 2.147 ± 0.481
3.68AsnLeu: 3.68 ± 1.138
0.307AsnMet: 0.307 ± 0.188
2.76AsnAsn: 2.76 ± 0.623
2.147AsnPro: 2.147 ± 1.665
0.0AsnGln: 0.0 ± 0.0
1.227AsnArg: 1.227 ± 1.14
5.52AsnSer: 5.52 ± 0.58
2.147AsnThr: 2.147 ± 0.481
3.987AsnVal: 3.987 ± 0.602
1.227AsnTrp: 1.227 ± 0.301
2.76AsnTyr: 2.76 ± 1.175
0.0AsnXaa: 0.0 ± 0.0
Pro
2.147ProAla: 2.147 ± 0.724
2.147ProCys: 2.147 ± 0.481
2.147ProAsp: 2.147 ± 0.714
3.067ProGlu: 3.067 ± 0.311
3.373ProPhe: 3.373 ± 0.562
2.453ProGly: 2.453 ± 0.574
1.533ProHis: 1.533 ± 0.347
4.6ProIle: 4.6 ± 0.316
2.147ProLys: 2.147 ± 0.308
2.147ProLeu: 2.147 ± 0.714
0.0ProMet: 0.0 ± 0.0
1.84ProAsn: 1.84 ± 0.258
1.533ProPro: 1.533 ± 0.347
1.227ProGln: 1.227 ± 0.301
0.92ProArg: 0.92 ± 0.235
2.453ProSer: 2.453 ± 0.601
1.84ProThr: 1.84 ± 1.693
6.746ProVal: 6.746 ± 0.549
0.307ProTrp: 0.307 ± 0.506
1.227ProTyr: 1.227 ± 0.301
0.0ProXaa: 0.0 ± 0.0
Gln
1.533GlnAla: 1.533 ± 0.347
0.92GlnCys: 0.92 ± 0.235
0.0GlnAsp: 0.0 ± 0.0
0.307GlnGlu: 0.307 ± 0.188
0.307GlnPhe: 0.307 ± 0.188
1.533GlnGly: 1.533 ± 1.756
0.613GlnHis: 0.613 ± 0.151
1.84GlnIle: 1.84 ± 0.452
0.307GlnLys: 0.307 ± 0.188
3.68GlnLeu: 3.68 ± 0.764
1.84GlnMet: 1.84 ± 0.452
0.307GlnAsn: 0.307 ± 0.188
1.533GlnPro: 1.533 ± 0.577
0.92GlnGln: 0.92 ± 0.528
1.227GlnArg: 1.227 ± 0.477
4.293GlnSer: 4.293 ± 0.585
1.533GlnThr: 1.533 ± 0.497
1.533GlnVal: 1.533 ± 0.331
1.227GlnTrp: 1.227 ± 0.301
0.613GlnTyr: 0.613 ± 0.151
0.0GlnXaa: 0.0 ± 0.0
Arg
3.68ArgAla: 3.68 ± 0.504
0.92ArgCys: 0.92 ± 0.235
3.067ArgAsp: 3.067 ± 1.081
1.227ArgGlu: 1.227 ± 0.9
2.453ArgPhe: 2.453 ± 1.038
1.227ArgGly: 1.227 ± 0.346
0.92ArgHis: 0.92 ± 0.4
0.92ArgIle: 0.92 ± 0.235
4.906ArgLys: 4.906 ± 1.102
3.373ArgLeu: 3.373 ± 0.589
0.307ArgMet: 0.307 ± 0.506
2.76ArgAsn: 2.76 ± 0.405
2.147ArgPro: 2.147 ± 0.481
1.533ArgGln: 1.533 ± 0.347
3.987ArgArg: 3.987 ± 0.914
3.68ArgSer: 3.68 ± 0.483
1.84ArgThr: 1.84 ± 0.407
7.666ArgVal: 7.666 ± 0.792
0.0ArgTrp: 0.0 ± 0.0
1.227ArgTyr: 1.227 ± 0.301
0.0ArgXaa: 0.0 ± 0.0
Ser
3.987SerAla: 3.987 ± 0.919
1.227SerCys: 1.227 ± 0.301
8.586SerAsp: 8.586 ± 0.956
3.067SerGlu: 3.067 ± 0.753
5.826SerPhe: 5.826 ± 0.783
4.6SerGly: 4.6 ± 2.682
1.227SerHis: 1.227 ± 0.301
6.44SerIle: 6.44 ± 1.324
6.44SerLys: 6.44 ± 1.124
10.12SerLeu: 10.12 ± 1.513
1.533SerMet: 1.533 ± 0.347
3.067SerAsn: 3.067 ± 2.579
5.52SerPro: 5.52 ± 1.442
2.453SerGln: 2.453 ± 0.693
1.84SerArg: 1.84 ± 0.702
7.053SerSer: 7.053 ± 3.768
2.453SerThr: 2.453 ± 0.601
11.04SerVal: 11.04 ± 2.111
0.92SerTrp: 0.92 ± 0.4
0.92SerTyr: 0.92 ± 0.4
0.0SerXaa: 0.0 ± 0.0
Thr
3.987ThrAla: 3.987 ± 0.898
0.613ThrCys: 0.613 ± 0.151
3.68ThrAsp: 3.68 ± 0.284
3.373ThrGlu: 3.373 ± 0.377
4.6ThrPhe: 4.6 ± 1.062
3.987ThrGly: 3.987 ± 0.446
2.147ThrHis: 2.147 ± 0.481
2.147ThrIle: 2.147 ± 0.308
5.213ThrLys: 5.213 ± 0.589
6.133ThrLeu: 6.133 ± 0.619
0.92ThrMet: 0.92 ± 0.235
0.92ThrAsn: 0.92 ± 0.878
3.373ThrPro: 3.373 ± 0.437
1.227ThrGln: 1.227 ± 1.14
2.76ThrArg: 2.76 ± 0.481
2.76ThrSer: 2.76 ± 0.57
2.76ThrThr: 2.76 ± 0.481
4.6ThrVal: 4.6 ± 1.18
1.533ThrTrp: 1.533 ± 0.469
2.453ThrTyr: 2.453 ± 0.603
0.0ThrXaa: 0.0 ± 0.0
Val
4.906ValAla: 4.906 ± 0.485
0.307ValCys: 0.307 ± 0.506
8.893ValAsp: 8.893 ± 0.792
7.053ValGlu: 7.053 ± 0.772
5.52ValPhe: 5.52 ± 0.797
1.533ValGly: 1.533 ± 1.254
1.84ValHis: 1.84 ± 0.452
3.68ValIle: 3.68 ± 0.785
5.213ValLys: 5.213 ± 0.589
8.586ValLeu: 8.586 ± 1.449
1.533ValMet: 1.533 ± 0.347
6.746ValAsn: 6.746 ± 0.731
3.373ValPro: 3.373 ± 1.389
1.533ValGln: 1.533 ± 0.497
7.36ValArg: 7.36 ± 1.157
10.426ValSer: 10.426 ± 0.893
7.36ValThr: 7.36 ± 0.184
6.746ValVal: 6.746 ± 1.826
1.227ValTrp: 1.227 ± 0.346
3.373ValTyr: 3.373 ± 0.806
0.0ValXaa: 0.0 ± 0.0
Trp
0.613TrpAla: 0.613 ± 0.578
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.92TrpGlu: 0.92 ± 0.235
1.227TrpPhe: 1.227 ± 0.301
0.613TrpGly: 0.613 ± 0.151
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.613TrpLys: 0.613 ± 0.151
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.227TrpAsn: 1.227 ± 0.399
0.0TrpPro: 0.0 ± 0.0
0.613TrpGln: 0.613 ± 0.151
0.0TrpArg: 0.0 ± 0.0
0.307TrpSer: 0.307 ± 0.506
0.307TrpThr: 0.307 ± 0.506
2.76TrpVal: 2.76 ± 0.381
0.0TrpTrp: 0.0 ± 0.0
0.307TrpTyr: 0.307 ± 0.188
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.227TyrAla: 1.227 ± 0.301
0.0TyrCys: 0.0 ± 0.0
3.987TyrAsp: 3.987 ± 0.919
0.92TyrGlu: 0.92 ± 0.4
2.147TyrPhe: 2.147 ± 0.308
0.613TyrGly: 0.613 ± 0.151
1.84TyrHis: 1.84 ± 0.471
0.92TyrIle: 0.92 ± 0.235
1.533TyrLys: 1.533 ± 0.331
2.453TyrLeu: 2.453 ± 0.387
1.533TyrMet: 1.533 ± 0.347
0.92TyrAsn: 0.92 ± 0.528
3.373TyrPro: 3.373 ± 0.806
0.92TyrGln: 0.92 ± 0.235
0.613TyrArg: 0.613 ± 0.151
1.227TyrSer: 1.227 ± 0.818
4.293TyrThr: 4.293 ± 0.962
2.147TyrVal: 2.147 ± 1.281
0.0TyrTrp: 0.0 ± 0.0
1.227TyrTyr: 1.227 ± 0.399
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.307XaaGln: 0.307 ± 0.188
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3262 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski