Amino acid dipepetide frequency for Brevilactibacter sinopodophylli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.775AlaAla: 18.775 ± 0.218	1.03AlaCys: 1.03 ± 0.033	8.65AlaAsp: 8.65 ± 0.114	8.177AlaGlu: 8.177 ± 0.114	3.796AlaPhe: 3.796 ± 0.063	12.03AlaGly: 12.03 ± 0.141	2.761AlaHis: 2.761 ± 0.062	5.056AlaIle: 5.056 ± 0.078	2.827AlaLys: 2.827 ± 0.076	14.14AlaLeu: 14.14 ± 0.168	2.928AlaMet: 2.928 ± 0.051	2.416AlaAsn: 2.416 ± 0.048	6.547AlaPro: 6.547 ± 0.112	3.99AlaGln: 3.99 ± 0.077	9.554AlaArg: 9.554 ± 0.139	7.624AlaSer: 7.624 ± 0.089	7.582AlaThr: 7.582 ± 0.097	10.836AlaVal: 10.836 ± 0.112	2.322AlaTrp: 2.322 ± 0.052	2.282AlaTyr: 2.282 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.831CysAla: 0.831 ± 0.03	0.08CysCys: 0.08 ± 0.01	0.404CysAsp: 0.404 ± 0.022	0.315CysGlu: 0.315 ± 0.017	0.223CysPhe: 0.223 ± 0.016	0.783CysGly: 0.783 ± 0.029	0.208CysHis: 0.208 ± 0.017	0.225CysIle: 0.225 ± 0.016	0.077CysLys: 0.077 ± 0.01	0.578CysLeu: 0.578 ± 0.027	0.104CysMet: 0.104 ± 0.01	0.128CysAsn: 0.128 ± 0.013	0.49CysPro: 0.49 ± 0.022	0.16CysGln: 0.16 ± 0.013	0.499CysArg: 0.499 ± 0.023	0.408CysSer: 0.408 ± 0.023	0.463CysThr: 0.463 ± 0.025	0.534CysVal: 0.534 ± 0.026	0.102CysTrp: 0.102 ± 0.01	0.11CysTyr: 0.11 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.734AspAla: 9.734 ± 0.113	0.325AspCys: 0.325 ± 0.02	3.879AspAsp: 3.879 ± 0.079	4.127AspGlu: 4.127 ± 0.078	1.633AspPhe: 1.633 ± 0.039	5.678AspGly: 5.678 ± 0.103	1.505AspHis: 1.505 ± 0.044	2.116AspIle: 2.116 ± 0.055	1.148AspLys: 1.148 ± 0.045	6.797AspLeu: 6.797 ± 0.082	0.882AspMet: 0.882 ± 0.034	0.974AspAsn: 0.974 ± 0.037	4.458AspPro: 4.458 ± 0.085	1.674AspGln: 1.674 ± 0.039	4.26AspArg: 4.26 ± 0.078	2.276AspSer: 2.276 ± 0.055	2.947AspThr: 2.947 ± 0.061	5.378AspVal: 5.378 ± 0.08	1.045AspTrp: 1.045 ± 0.036	1.105AspTyr: 1.105 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	7.7GluAla: 7.7 ± 0.12	0.307GluCys: 0.307 ± 0.018	2.793GluAsp: 2.793 ± 0.072	3.007GluGlu: 3.007 ± 0.071	1.66GluPhe: 1.66 ± 0.048	4.499GluGly: 4.499 ± 0.072	1.464GluHis: 1.464 ± 0.041	2.113GluIle: 2.113 ± 0.064	1.346GluLys: 1.346 ± 0.04	6.126GluLeu: 6.126 ± 0.082	1.031GluMet: 1.031 ± 0.035	1.053GluAsn: 1.053 ± 0.04	3.242GluPro: 3.242 ± 0.057	2.138GluGln: 2.138 ± 0.051	5.096GluArg: 5.096 ± 0.088	2.456GluSer: 2.456 ± 0.053	2.637GluThr: 2.637 ± 0.052	5.478GluVal: 5.478 ± 0.085	0.744GluTrp: 0.744 ± 0.031	1.024GluTyr: 1.024 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.879PheAla: 3.879 ± 0.077	0.22PheCys: 0.22 ± 0.015	2.227PheAsp: 2.227 ± 0.052	1.639PheGlu: 1.639 ± 0.04	1.009PhePhe: 1.009 ± 0.038	3.224PheGly: 3.224 ± 0.065	0.614PheHis: 0.614 ± 0.025	1.075PheIle: 1.075 ± 0.041	0.582PheLys: 0.582 ± 0.028	2.761PheLeu: 2.761 ± 0.06	0.49PheMet: 0.49 ± 0.026	0.725PheAsn: 0.725 ± 0.028	1.352PhePro: 1.352 ± 0.046	0.66PheGln: 0.66 ± 0.03	1.708PheArg: 1.708 ± 0.042	1.651PheSer: 1.651 ± 0.05	2.083PheThr: 2.083 ± 0.047	2.733PheVal: 2.733 ± 0.057	0.462PheTrp: 0.462 ± 0.024	0.552PheTyr: 0.552 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	10.107GlyAla: 10.107 ± 0.116	0.707GlyCys: 0.707 ± 0.028	5.005GlyAsp: 5.005 ± 0.083	5.008GlyGlu: 5.008 ± 0.086	3.078GlyPhe: 3.078 ± 0.054	7.721GlyGly: 7.721 ± 0.12	2.118GlyHis: 2.118 ± 0.053	3.876GlyIle: 3.876 ± 0.068	2.13GlyLys: 2.13 ± 0.062	9.636GlyLeu: 9.636 ± 0.104	2.132GlyMet: 2.132 ± 0.047	1.775GlyAsn: 1.775 ± 0.053	4.275GlyPro: 4.275 ± 0.07	2.833GlyGln: 2.833 ± 0.061	7.273GlyArg: 7.273 ± 0.111	4.867GlySer: 4.867 ± 0.073	5.516GlyThr: 5.516 ± 0.09	8.374GlyVal: 8.374 ± 0.105	1.88GlyTrp: 1.88 ± 0.054	2.147GlyTyr: 2.147 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.71HisAla: 2.71 ± 0.061	0.183HisCys: 0.183 ± 0.015	1.448HisAsp: 1.448 ± 0.045	1.146HisGlu: 1.146 ± 0.036	0.523HisPhe: 0.523 ± 0.022	2.104HisGly: 2.104 ± 0.05	0.676HisHis: 0.676 ± 0.028	0.678HisIle: 0.678 ± 0.025	0.361HisLys: 0.361 ± 0.021	2.538HisLeu: 2.538 ± 0.057	0.343HisMet: 0.343 ± 0.02	0.395HisAsn: 0.395 ± 0.023	1.702HisPro: 1.702 ± 0.05	0.603HisGln: 0.603 ± 0.028	1.831HisArg: 1.831 ± 0.053	0.924HisSer: 0.924 ± 0.029	1.267HisThr: 1.267 ± 0.035	1.901HisVal: 1.901 ± 0.047	0.331HisTrp: 0.331 ± 0.018	0.465HisTyr: 0.465 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.486IleAla: 5.486 ± 0.09	0.297IleCys: 0.297 ± 0.017	2.797IleAsp: 2.797 ± 0.053	2.492IleGlu: 2.492 ± 0.057	0.914IlePhe: 0.914 ± 0.036	3.818IleGly: 3.818 ± 0.081	0.705IleHis: 0.705 ± 0.029	1.587IleIle: 1.587 ± 0.049	0.868IleLys: 0.868 ± 0.032	3.191IleLeu: 3.191 ± 0.064	0.67IleMet: 0.67 ± 0.027	0.926IleAsn: 0.926 ± 0.032	2.098IlePro: 2.098 ± 0.045	0.885IleGln: 0.885 ± 0.037	2.356IleArg: 2.356 ± 0.048	1.815IleSer: 1.815 ± 0.049	2.499IleThr: 2.499 ± 0.052	3.585IleVal: 3.585 ± 0.076	0.414IleTrp: 0.414 ± 0.023	0.66IleTyr: 0.66 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	2.811LysAla: 2.811 ± 0.072	0.097LysCys: 0.097 ± 0.01	1.088LysAsp: 1.088 ± 0.04	1.065LysGlu: 1.065 ± 0.042	0.559LysPhe: 0.559 ± 0.026	1.804LysGly: 1.804 ± 0.049	0.453LysHis: 0.453 ± 0.022	0.892LysIle: 0.892 ± 0.038	0.808LysLys: 0.808 ± 0.035	2.045LysLeu: 2.045 ± 0.052	0.441LysMet: 0.441 ± 0.021	0.508LysAsn: 0.508 ± 0.024	1.205LysPro: 1.205 ± 0.039	0.692LysGln: 0.692 ± 0.029	1.562LysArg: 1.562 ± 0.045	1.037LysSer: 1.037 ± 0.036	1.193LysThr: 1.193 ± 0.041	2.022LysVal: 2.022 ± 0.053	0.206LysTrp: 0.206 ± 0.016	0.478LysTyr: 0.478 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	15.66LeuAla: 15.66 ± 0.157	0.609LeuCys: 0.609 ± 0.026	6.955LeuAsp: 6.955 ± 0.094	5.08LeuGlu: 5.08 ± 0.086	2.748LeuPhe: 2.748 ± 0.064	9.928LeuGly: 9.928 ± 0.129	2.069LeuHis: 2.069 ± 0.048	3.441LeuIle: 3.441 ± 0.074	1.952LeuLys: 1.952 ± 0.052	10.204LeuLeu: 10.204 ± 0.153	1.907LeuMet: 1.907 ± 0.048	2.001LeuAsn: 2.001 ± 0.051	5.834LeuPro: 5.834 ± 0.08	2.403LeuGln: 2.403 ± 0.057	7.453LeuArg: 7.453 ± 0.101	5.214LeuSer: 5.214 ± 0.079	6.498LeuThr: 6.498 ± 0.096	10.197LeuVal: 10.197 ± 0.121	1.359LeuTrp: 1.359 ± 0.043	1.614LeuTyr: 1.614 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.683MetAla: 2.683 ± 0.048	0.116MetCys: 0.116 ± 0.013	0.981MetAsp: 0.981 ± 0.03	0.796MetGlu: 0.796 ± 0.037	0.59MetPhe: 0.59 ± 0.028	1.653MetGly: 1.653 ± 0.041	0.326MetHis: 0.326 ± 0.017	0.77MetIle: 0.77 ± 0.033	0.513MetLys: 0.513 ± 0.022	1.965MetLeu: 1.965 ± 0.046	0.405MetMet: 0.405 ± 0.024	0.514MetAsn: 0.514 ± 0.021	1.176MetPro: 1.176 ± 0.033	0.502MetGln: 0.502 ± 0.023	1.36MetArg: 1.36 ± 0.041	1.309MetSer: 1.309 ± 0.036	1.658MetThr: 1.658 ± 0.047	1.791MetVal: 1.791 ± 0.042	0.238MetTrp: 0.238 ± 0.015	0.258MetTyr: 0.258 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	2.571AsnAla: 2.571 ± 0.053	0.147AsnCys: 0.147 ± 0.013	1.11AsnAsp: 1.11 ± 0.038	1.051AsnGlu: 1.051 ± 0.039	0.58AsnPhe: 0.58 ± 0.027	1.755AsnGly: 1.755 ± 0.051	0.469AsnHis: 0.469 ± 0.022	0.786AsnIle: 0.786 ± 0.029	0.475AsnLys: 0.475 ± 0.025	2.033AsnLeu: 2.033 ± 0.047	0.365AsnMet: 0.365 ± 0.02	0.527AsnAsn: 0.527 ± 0.028	1.687AsnPro: 1.687 ± 0.045	0.622AsnGln: 0.622 ± 0.028	1.448AsnArg: 1.448 ± 0.045	0.872AsnSer: 0.872 ± 0.031	1.181AsnThr: 1.181 ± 0.038	1.572AsnVal: 1.572 ± 0.043	0.339AsnTrp: 0.339 ± 0.019	0.462AsnTyr: 0.462 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.316ProAla: 7.316 ± 0.109	0.29ProCys: 0.29 ± 0.018	4.503ProAsp: 4.503 ± 0.08	4.008ProGlu: 4.008 ± 0.077	1.642ProPhe: 1.642 ± 0.041	5.792ProGly: 5.792 ± 0.092	1.245ProHis: 1.245 ± 0.041	1.924ProIle: 1.924 ± 0.047	1.112ProLys: 1.112 ± 0.039	5.135ProLeu: 5.135 ± 0.073	1.105ProMet: 1.105 ± 0.036	1.13ProAsn: 1.13 ± 0.037	2.832ProPro: 2.832 ± 0.071	1.574ProGln: 1.574 ± 0.041	3.658ProArg: 3.658 ± 0.061	3.009ProSer: 3.009 ± 0.066	3.881ProThr: 3.881 ± 0.085	5.072ProVal: 5.072 ± 0.085	1.078ProTrp: 1.078 ± 0.04	1.113ProTyr: 1.113 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.97GlnAla: 3.97 ± 0.076	0.161GlnCys: 0.161 ± 0.013	1.161GlnAsp: 1.161 ± 0.039	1.294GlnGlu: 1.294 ± 0.034	0.869GlnPhe: 0.869 ± 0.033	2.219GlnGly: 2.219 ± 0.059	0.667GlnHis: 0.667 ± 0.029	1.058GlnIle: 1.058 ± 0.035	0.544GlnLys: 0.544 ± 0.025	3.118GlnLeu: 3.118 ± 0.064	0.586GlnMet: 0.586 ± 0.026	0.518GlnAsn: 0.518 ± 0.023	1.757GlnPro: 1.757 ± 0.047	1.198GlnGln: 1.198 ± 0.048	2.554GlnArg: 2.554 ± 0.06	1.224GlnSer: 1.224 ± 0.04	1.392GlnThr: 1.392 ± 0.043	2.896GlnVal: 2.896 ± 0.058	0.501GlnTrp: 0.501 ± 0.026	0.581GlnTyr: 0.581 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	8.997ArgAla: 8.997 ± 0.125	0.459ArgCys: 0.459 ± 0.022	4.226ArgAsp: 4.226 ± 0.07	4.193ArgGlu: 4.193 ± 0.072	2.332ArgPhe: 2.332 ± 0.052	5.551ArgGly: 5.551 ± 0.087	1.757ArgHis: 1.757 ± 0.045	3.125ArgIle: 3.125 ± 0.063	1.487ArgLys: 1.487 ± 0.04	7.902ArgLeu: 7.902 ± 0.111	1.688ArgMet: 1.688 ± 0.043	1.449ArgAsn: 1.449 ± 0.043	4.567ArgPro: 4.567 ± 0.084	2.218ArgGln: 2.218 ± 0.05	6.924ArgArg: 6.924 ± 0.115	3.709ArgSer: 3.709 ± 0.061	4.624ArgThr: 4.624 ± 0.066	6.361ArgVal: 6.361 ± 0.081	1.448ArgTrp: 1.448 ± 0.043	1.54ArgTyr: 1.54 ± 0.045	0.0ArgXaa: 0.0 ± 0.0
Ser	6.078SerAla: 6.078 ± 0.091	0.383SerCys: 0.383 ± 0.022	3.033SerAsp: 3.033 ± 0.06	2.396SerGlu: 2.396 ± 0.062	1.695SerPhe: 1.695 ± 0.04	5.437SerGly: 5.437 ± 0.078	1.042SerHis: 1.042 ± 0.035	2.076SerIle: 2.076 ± 0.052	0.978SerLys: 0.978 ± 0.038	5.117SerLeu: 5.117 ± 0.085	1.185SerMet: 1.185 ± 0.04	1.065SerAsn: 1.065 ± 0.035	3.001SerPro: 3.001 ± 0.066	1.307SerGln: 1.307 ± 0.041	3.579SerArg: 3.579 ± 0.069	2.701SerSer: 2.701 ± 0.065	3.202SerThr: 3.202 ± 0.065	4.349SerVal: 4.349 ± 0.071	0.881SerTrp: 0.881 ± 0.032	1.114SerTyr: 1.114 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.052ThrAla: 7.052 ± 0.099	0.44ThrCys: 0.44 ± 0.021	3.661ThrAsp: 3.661 ± 0.06	2.958ThrGlu: 2.958 ± 0.057	1.968ThrPhe: 1.968 ± 0.045	5.637ThrGly: 5.637 ± 0.082	1.369ThrHis: 1.369 ± 0.04	2.66ThrIle: 2.66 ± 0.054	1.279ThrLys: 1.279 ± 0.042	6.159ThrLeu: 6.159 ± 0.079	1.162ThrMet: 1.162 ± 0.034	1.31ThrAsn: 1.31 ± 0.037	4.311ThrPro: 4.311 ± 0.082	1.589ThrGln: 1.589 ± 0.042	3.96ThrArg: 3.96 ± 0.073	3.148ThrSer: 3.148 ± 0.063	3.944ThrThr: 3.944 ± 0.064	5.51ThrVal: 5.51 ± 0.083	1.132ThrTrp: 1.132 ± 0.04	1.339ThrTyr: 1.339 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	12.544ValAla: 12.544 ± 0.152	0.592ValCys: 0.592 ± 0.026	5.888ValAsp: 5.888 ± 0.081	5.363ValGlu: 5.363 ± 0.083	2.633ValPhe: 2.633 ± 0.054	7.725ValGly: 7.725 ± 0.102	1.907ValHis: 1.907 ± 0.051	3.478ValIle: 3.478 ± 0.061	1.788ValLys: 1.788 ± 0.047	9.544ValLeu: 9.544 ± 0.13	1.622ValMet: 1.622 ± 0.045	1.858ValAsn: 1.858 ± 0.049	4.958ValPro: 4.958 ± 0.079	2.125ValGln: 2.125 ± 0.047	6.593ValArg: 6.593 ± 0.082	4.483ValSer: 4.483 ± 0.073	5.94ValThr: 5.94 ± 0.091	9.341ValVal: 9.341 ± 0.131	1.281ValTrp: 1.281 ± 0.039	1.43ValTyr: 1.43 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.982TrpAla: 1.982 ± 0.047	0.12TrpCys: 0.12 ± 0.012	0.853TrpAsp: 0.853 ± 0.033	0.743TrpGlu: 0.743 ± 0.026	0.565TrpPhe: 0.565 ± 0.025	1.234TrpGly: 1.234 ± 0.041	0.359TrpHis: 0.359 ± 0.018	0.607TrpIle: 0.607 ± 0.032	0.33TrpLys: 0.33 ± 0.02	2.038TrpLeu: 2.038 ± 0.055	0.305TrpMet: 0.305 ± 0.021	0.374TrpAsn: 0.374 ± 0.02	0.858TrpPro: 0.858 ± 0.029	0.564TrpGln: 0.564 ± 0.027	1.332TrpArg: 1.332 ± 0.037	0.955TrpSer: 0.955 ± 0.035	1.02TrpThr: 1.02 ± 0.034	1.506TrpVal: 1.506 ± 0.045	0.426TrpTrp: 0.426 ± 0.026	0.326TrpTyr: 0.326 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.437TyrAla: 2.437 ± 0.053	0.16TyrCys: 0.16 ± 0.013	1.28TyrAsp: 1.28 ± 0.048	1.056TyrGlu: 1.056 ± 0.038	0.631TyrPhe: 0.631 ± 0.027	1.867TyrGly: 1.867 ± 0.048	0.415TyrHis: 0.415 ± 0.022	0.52TyrIle: 0.52 ± 0.03	0.36TyrLys: 0.36 ± 0.02	2.099TyrLeu: 2.099 ± 0.052	0.252TyrMet: 0.252 ± 0.015	0.407TyrAsn: 0.407 ± 0.024	1.065TyrPro: 1.065 ± 0.038	0.529TyrGln: 0.529 ± 0.024	1.558TyrArg: 1.558 ± 0.042	0.939TyrSer: 0.939 ± 0.033	1.06TyrThr: 1.06 ± 0.038	1.66TyrVal: 1.66 ± 0.044	0.306TyrTrp: 0.306 ± 0.022	0.409TyrTyr: 0.409 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2777 proteins (911669 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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