Amino acid dipepetide frequency for Pseudomonas phage KPP10 (Bacteriophage KPP10)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.796AlaAla: 7.796 ± 0.661
1.162AlaCys: 1.162 ± 0.203
4.798AlaAsp: 4.798 ± 0.434
5.922AlaGlu: 5.922 ± 0.521
2.474AlaPhe: 2.474 ± 0.31
6.409AlaGly: 6.409 ± 0.557
1.762AlaHis: 1.762 ± 0.249
4.385AlaIle: 4.385 ± 0.397
4.91AlaLys: 4.91 ± 0.556
7.946AlaLeu: 7.946 ± 0.62
3.261AlaMet: 3.261 ± 0.344
3.186AlaAsn: 3.186 ± 0.424
3.111AlaPro: 3.111 ± 0.297
3.898AlaGln: 3.898 ± 0.443
5.172AlaArg: 5.172 ± 0.475
4.835AlaSer: 4.835 ± 0.437
4.873AlaThr: 4.873 ± 0.504
5.772AlaVal: 5.772 ± 0.59
1.987AlaTrp: 1.987 ± 0.27
2.136AlaTyr: 2.136 ± 0.297
0.0AlaXaa: 0.0 ± 0.0
Cys
0.975CysAla: 0.975 ± 0.182
0.3CysCys: 0.3 ± 0.12
0.787CysAsp: 0.787 ± 0.171
1.124CysGlu: 1.124 ± 0.203
0.675CysPhe: 0.675 ± 0.153
1.087CysGly: 1.087 ± 0.234
0.45CysHis: 0.45 ± 0.141
0.562CysIle: 0.562 ± 0.131
0.75CysLys: 0.75 ± 0.171
0.862CysLeu: 0.862 ± 0.18
0.412CysMet: 0.412 ± 0.143
0.487CysAsn: 0.487 ± 0.121
0.75CysPro: 0.75 ± 0.169
0.712CysGln: 0.712 ± 0.191
0.975CysArg: 0.975 ± 0.18
1.049CysSer: 1.049 ± 0.227
0.487CysThr: 0.487 ± 0.115
0.375CysVal: 0.375 ± 0.115
0.487CysTrp: 0.487 ± 0.141
0.45CysTyr: 0.45 ± 0.12
0.0CysXaa: 0.0 ± 0.0
Asp
4.948AspAla: 4.948 ± 0.463
1.087AspCys: 1.087 ± 0.2
3.336AspAsp: 3.336 ± 0.328
4.873AspGlu: 4.873 ± 0.457
2.586AspPhe: 2.586 ± 0.325
4.31AspGly: 4.31 ± 0.445
1.237AspHis: 1.237 ± 0.271
4.01AspIle: 4.01 ± 0.351
2.624AspLys: 2.624 ± 0.362
5.097AspLeu: 5.097 ± 0.413
1.724AspMet: 1.724 ± 0.242
2.099AspAsn: 2.099 ± 0.257
2.436AspPro: 2.436 ± 0.281
2.099AspGln: 2.099 ± 0.27
3.673AspArg: 3.673 ± 0.387
2.736AspSer: 2.736 ± 0.356
3.261AspThr: 3.261 ± 0.354
4.16AspVal: 4.16 ± 0.389
1.349AspTrp: 1.349 ± 0.196
1.837AspTyr: 1.837 ± 0.256
0.0AspXaa: 0.0 ± 0.0
Glu
7.271GluAla: 7.271 ± 0.515
0.975GluCys: 0.975 ± 0.17
4.498GluAsp: 4.498 ± 0.438
6.559GluGlu: 6.559 ± 0.6
3.336GluPhe: 3.336 ± 0.361
5.847GluGly: 5.847 ± 0.529
1.312GluHis: 1.312 ± 0.223
3.298GluIle: 3.298 ± 0.355
4.685GluLys: 4.685 ± 0.492
6.034GluLeu: 6.034 ± 0.51
2.661GluMet: 2.661 ± 0.311
2.924GluAsn: 2.924 ± 0.367
2.549GluPro: 2.549 ± 0.398
2.924GluGln: 2.924 ± 0.369
4.01GluArg: 4.01 ± 0.399
3.598GluSer: 3.598 ± 0.34
3.073GluThr: 3.073 ± 0.364
6.297GluVal: 6.297 ± 0.492
1.574GluTrp: 1.574 ± 0.219
2.549GluTyr: 2.549 ± 0.285
0.0GluXaa: 0.0 ± 0.0
Phe
2.549PheAla: 2.549 ± 0.322
0.562PheCys: 0.562 ± 0.132
2.624PheAsp: 2.624 ± 0.343
3.486PheGlu: 3.486 ± 0.367
1.199PhePhe: 1.199 ± 0.161
2.399PheGly: 2.399 ± 0.3
0.9PheHis: 0.9 ± 0.195
1.724PheIle: 1.724 ± 0.232
2.174PheLys: 2.174 ± 0.252
3.486PheLeu: 3.486 ± 0.403
0.75PheMet: 0.75 ± 0.138
1.387PheAsn: 1.387 ± 0.205
2.099PhePro: 2.099 ± 0.269
1.612PheGln: 1.612 ± 0.282
1.912PheArg: 1.912 ± 0.258
2.624PheSer: 2.624 ± 0.252
1.912PheThr: 1.912 ± 0.292
2.061PheVal: 2.061 ± 0.272
0.375PheTrp: 0.375 ± 0.162
1.087PheTyr: 1.087 ± 0.19
0.0PheXaa: 0.0 ± 0.0
Gly
5.472GlyAla: 5.472 ± 0.48
0.937GlyCys: 0.937 ± 0.177
3.898GlyAsp: 3.898 ± 0.349
4.723GlyGlu: 4.723 ± 0.463
2.999GlyPhe: 2.999 ± 0.295
5.51GlyGly: 5.51 ± 0.488
1.462GlyHis: 1.462 ± 0.227
3.523GlyIle: 3.523 ± 0.384
3.861GlyLys: 3.861 ± 0.434
5.885GlyLeu: 5.885 ± 0.55
2.586GlyMet: 2.586 ± 0.321
3.373GlyAsn: 3.373 ± 0.414
2.361GlyPro: 2.361 ± 0.286
2.511GlyGln: 2.511 ± 0.347
3.561GlyArg: 3.561 ± 0.342
4.123GlySer: 4.123 ± 0.494
3.598GlyThr: 3.598 ± 0.495
5.51GlyVal: 5.51 ± 0.442
1.687GlyTrp: 1.687 ± 0.273
3.673GlyTyr: 3.673 ± 0.439
0.0GlyXaa: 0.0 ± 0.0
His
1.687HisAla: 1.687 ± 0.271
0.337HisCys: 0.337 ± 0.117
1.612HisAsp: 1.612 ± 0.25
1.612HisGlu: 1.612 ± 0.218
0.6HisPhe: 0.6 ± 0.142
2.024HisGly: 2.024 ± 0.296
0.3HisHis: 0.3 ± 0.097
1.012HisIle: 1.012 ± 0.154
0.825HisLys: 0.825 ± 0.18
2.136HisLeu: 2.136 ± 0.269
0.637HisMet: 0.637 ± 0.151
0.6HisAsn: 0.6 ± 0.166
1.574HisPro: 1.574 ± 0.231
0.637HisGln: 0.637 ± 0.194
1.199HisArg: 1.199 ± 0.209
1.049HisSer: 1.049 ± 0.216
1.012HisThr: 1.012 ± 0.214
1.124HisVal: 1.124 ± 0.188
0.637HisTrp: 0.637 ± 0.124
0.525HisTyr: 0.525 ± 0.152
0.0HisXaa: 0.0 ± 0.0
Ile
3.786IleAla: 3.786 ± 0.345
0.675IleCys: 0.675 ± 0.162
2.811IleAsp: 2.811 ± 0.319
3.898IleGlu: 3.898 ± 0.336
1.424IlePhe: 1.424 ± 0.284
2.961IleGly: 2.961 ± 0.315
1.012IleHis: 1.012 ± 0.177
2.324IleIle: 2.324 ± 0.248
2.249IleLys: 2.249 ± 0.252
4.573IleLeu: 4.573 ± 0.428
0.862IleMet: 0.862 ± 0.149
2.174IleAsn: 2.174 ± 0.292
2.924IlePro: 2.924 ± 0.365
1.912IleGln: 1.912 ± 0.256
2.774IleArg: 2.774 ± 0.358
2.624IleSer: 2.624 ± 0.28
3.036IleThr: 3.036 ± 0.412
2.849IleVal: 2.849 ± 0.304
0.712IleTrp: 0.712 ± 0.178
1.424IleTyr: 1.424 ± 0.231
0.0IleXaa: 0.0 ± 0.0
Lys
6.709LysAla: 6.709 ± 0.61
0.562LysCys: 0.562 ± 0.135
3.373LysAsp: 3.373 ± 0.386
4.685LysGlu: 4.685 ± 0.429
1.912LysPhe: 1.912 ± 0.235
4.198LysGly: 4.198 ± 0.395
1.612LysHis: 1.612 ± 0.241
2.099LysIle: 2.099 ± 0.354
3.523LysLys: 3.523 ± 0.422
5.285LysLeu: 5.285 ± 0.458
2.286LysMet: 2.286 ± 0.278
2.661LysAsn: 2.661 ± 0.289
1.687LysPro: 1.687 ± 0.252
1.912LysGln: 1.912 ± 0.233
2.924LysArg: 2.924 ± 0.386
2.661LysSer: 2.661 ± 0.339
2.511LysThr: 2.511 ± 0.343
4.498LysVal: 4.498 ± 0.463
0.937LysTrp: 0.937 ± 0.202
1.762LysTyr: 1.762 ± 0.254
0.0LysXaa: 0.0 ± 0.0
Leu
8.658LeuAla: 8.658 ± 0.642
1.199LeuCys: 1.199 ± 0.212
6.034LeuAsp: 6.034 ± 0.444
6.634LeuGlu: 6.634 ± 0.498
2.999LeuPhe: 2.999 ± 0.321
5.697LeuGly: 5.697 ± 0.474
1.424LeuHis: 1.424 ± 0.219
3.636LeuIle: 3.636 ± 0.377
5.51LeuLys: 5.51 ± 0.446
5.772LeuLeu: 5.772 ± 0.552
2.361LeuMet: 2.361 ± 0.26
3.486LeuAsn: 3.486 ± 0.371
4.273LeuPro: 4.273 ± 0.499
3.373LeuGln: 3.373 ± 0.378
5.622LeuArg: 5.622 ± 0.473
5.285LeuSer: 5.285 ± 0.465
5.172LeuThr: 5.172 ± 0.472
4.91LeuVal: 4.91 ± 0.41
1.049LeuTrp: 1.049 ± 0.177
3.223LeuTyr: 3.223 ± 0.468
0.0LeuXaa: 0.0 ± 0.0
Met
2.886MetAla: 2.886 ± 0.436
0.337MetCys: 0.337 ± 0.099
1.762MetAsp: 1.762 ± 0.211
2.361MetGlu: 2.361 ± 0.327
0.712MetPhe: 0.712 ± 0.141
2.024MetGly: 2.024 ± 0.287
0.637MetHis: 0.637 ± 0.16
1.312MetIle: 1.312 ± 0.212
2.211MetLys: 2.211 ± 0.232
2.174MetLeu: 2.174 ± 0.326
0.712MetMet: 0.712 ± 0.156
1.274MetAsn: 1.274 ± 0.266
1.349MetPro: 1.349 ± 0.196
1.162MetGln: 1.162 ± 0.194
1.687MetArg: 1.687 ± 0.282
2.061MetSer: 2.061 ± 0.251
1.949MetThr: 1.949 ± 0.28
1.874MetVal: 1.874 ± 0.247
0.3MetTrp: 0.3 ± 0.1
0.862MetTyr: 0.862 ± 0.18
0.0MetXaa: 0.0 ± 0.0
Asn
3.036AsnAla: 3.036 ± 0.375
0.412AsnCys: 0.412 ± 0.133
1.837AsnAsp: 1.837 ± 0.198
2.361AsnGlu: 2.361 ± 0.323
1.537AsnPhe: 1.537 ± 0.254
3.223AsnGly: 3.223 ± 0.354
0.975AsnHis: 0.975 ± 0.197
2.549AsnIle: 2.549 ± 0.323
2.286AsnLys: 2.286 ± 0.296
3.373AsnLeu: 3.373 ± 0.497
0.937AsnMet: 0.937 ± 0.178
1.612AsnAsn: 1.612 ± 0.3
2.774AsnPro: 2.774 ± 0.289
1.462AsnGln: 1.462 ± 0.259
1.987AsnArg: 1.987 ± 0.243
2.549AsnSer: 2.549 ± 0.277
2.136AsnThr: 2.136 ± 0.363
2.849AsnVal: 2.849 ± 0.28
0.6AsnTrp: 0.6 ± 0.161
1.124AsnTyr: 1.124 ± 0.188
0.0AsnXaa: 0.0 ± 0.0
Pro
3.561ProAla: 3.561 ± 0.406
0.45ProCys: 0.45 ± 0.155
2.324ProAsp: 2.324 ± 0.349
4.348ProGlu: 4.348 ± 0.336
1.724ProPhe: 1.724 ± 0.283
3.298ProGly: 3.298 ± 0.431
1.049ProHis: 1.049 ± 0.184
1.387ProIle: 1.387 ± 0.198
2.886ProLys: 2.886 ± 0.329
3.411ProLeu: 3.411 ± 0.352
0.937ProMet: 0.937 ± 0.169
1.912ProAsn: 1.912 ± 0.27
1.987ProPro: 1.987 ± 0.4
1.687ProGln: 1.687 ± 0.302
1.987ProArg: 1.987 ± 0.308
2.624ProSer: 2.624 ± 0.312
2.736ProThr: 2.736 ± 0.331
3.861ProVal: 3.861 ± 0.373
0.712ProTrp: 0.712 ± 0.148
1.724ProTyr: 1.724 ± 0.219
0.0ProXaa: 0.0 ± 0.0
Gln
4.61GlnAla: 4.61 ± 0.403
0.262GlnCys: 0.262 ± 0.103
2.024GlnAsp: 2.024 ± 0.245
3.298GlnGlu: 3.298 ± 0.331
1.387GlnPhe: 1.387 ± 0.24
2.774GlnGly: 2.774 ± 0.312
1.162GlnHis: 1.162 ± 0.249
1.912GlnIle: 1.912 ± 0.294
1.724GlnLys: 1.724 ± 0.324
2.924GlnLeu: 2.924 ± 0.323
1.537GlnMet: 1.537 ± 0.32
1.312GlnAsn: 1.312 ± 0.231
1.612GlnPro: 1.612 ± 0.235
1.987GlnGln: 1.987 ± 0.334
2.136GlnArg: 2.136 ± 0.304
1.649GlnSer: 1.649 ± 0.248
2.174GlnThr: 2.174 ± 0.26
3.448GlnVal: 3.448 ± 0.329
0.862GlnTrp: 0.862 ± 0.181
1.199GlnTyr: 1.199 ± 0.202
0.0GlnXaa: 0.0 ± 0.0
Arg
4.498ArgAla: 4.498 ± 0.353
0.975ArgCys: 0.975 ± 0.177
3.936ArgAsp: 3.936 ± 0.402
4.01ArgGlu: 4.01 ± 0.342
2.549ArgPhe: 2.549 ± 0.278
3.111ArgGly: 3.111 ± 0.307
1.199ArgHis: 1.199 ± 0.206
2.849ArgIle: 2.849 ± 0.286
3.936ArgLys: 3.936 ± 0.417
5.622ArgLeu: 5.622 ± 0.473
1.574ArgMet: 1.574 ± 0.223
2.324ArgAsn: 2.324 ± 0.338
1.949ArgPro: 1.949 ± 0.309
3.111ArgGln: 3.111 ± 0.306
3.448ArgArg: 3.448 ± 0.342
2.174ArgSer: 2.174 ± 0.3
3.298ArgThr: 3.298 ± 0.371
3.748ArgVal: 3.748 ± 0.384
0.937ArgTrp: 0.937 ± 0.175
1.762ArgTyr: 1.762 ± 0.294
0.0ArgXaa: 0.0 ± 0.0
Ser
3.748SerAla: 3.748 ± 0.372
1.124SerCys: 1.124 ± 0.199
3.073SerAsp: 3.073 ± 0.321
3.486SerGlu: 3.486 ± 0.302
2.286SerPhe: 2.286 ± 0.302
4.01SerGly: 4.01 ± 0.426
1.012SerHis: 1.012 ± 0.235
1.949SerIle: 1.949 ± 0.23
3.448SerLys: 3.448 ± 0.344
4.798SerLeu: 4.798 ± 0.465
1.612SerMet: 1.612 ± 0.297
2.174SerAsn: 2.174 ± 0.289
3.073SerPro: 3.073 ± 0.434
2.436SerGln: 2.436 ± 0.32
3.223SerArg: 3.223 ± 0.288
3.448SerSer: 3.448 ± 0.431
3.486SerThr: 3.486 ± 0.359
4.048SerVal: 4.048 ± 0.393
1.162SerTrp: 1.162 ± 0.177
2.136SerTyr: 2.136 ± 0.281
0.0SerXaa: 0.0 ± 0.0
Thr
4.76ThrAla: 4.76 ± 0.545
0.787ThrCys: 0.787 ± 0.17
3.261ThrAsp: 3.261 ± 0.388
3.186ThrGlu: 3.186 ± 0.353
2.136ThrPhe: 2.136 ± 0.315
4.123ThrGly: 4.123 ± 0.398
1.199ThrHis: 1.199 ± 0.188
2.961ThrIle: 2.961 ± 0.329
2.136ThrLys: 2.136 ± 0.32
6.184ThrLeu: 6.184 ± 0.532
1.387ThrMet: 1.387 ± 0.238
1.912ThrAsn: 1.912 ± 0.278
2.999ThrPro: 2.999 ± 0.352
2.061ThrGln: 2.061 ± 0.3
2.586ThrArg: 2.586 ± 0.298
3.261ThrSer: 3.261 ± 0.333
2.999ThrThr: 2.999 ± 0.363
4.423ThrVal: 4.423 ± 0.404
1.124ThrTrp: 1.124 ± 0.193
1.799ThrTyr: 1.799 ± 0.274
0.0ThrXaa: 0.0 ± 0.0
Val
4.91ValAla: 4.91 ± 0.485
0.862ValCys: 0.862 ± 0.177
3.673ValAsp: 3.673 ± 0.437
6.109ValGlu: 6.109 ± 0.563
2.661ValPhe: 2.661 ± 0.35
4.76ValGly: 4.76 ± 0.491
1.387ValHis: 1.387 ± 0.265
3.486ValIle: 3.486 ± 0.329
4.76ValLys: 4.76 ± 0.463
5.96ValLeu: 5.96 ± 0.536
2.249ValMet: 2.249 ± 0.245
2.586ValAsn: 2.586 ± 0.274
3.111ValPro: 3.111 ± 0.319
2.624ValGln: 2.624 ± 0.286
4.123ValArg: 4.123 ± 0.42
4.16ValSer: 4.16 ± 0.382
3.898ValThr: 3.898 ± 0.376
5.247ValVal: 5.247 ± 0.513
1.162ValTrp: 1.162 ± 0.201
2.699ValTyr: 2.699 ± 0.33
0.0ValXaa: 0.0 ± 0.0
Trp
1.687TrpAla: 1.687 ± 0.256
0.15TrpCys: 0.15 ± 0.08
1.199TrpAsp: 1.199 ± 0.224
1.312TrpGlu: 1.312 ± 0.261
0.562TrpPhe: 0.562 ± 0.146
1.274TrpGly: 1.274 ± 0.248
0.375TrpHis: 0.375 ± 0.121
0.862TrpIle: 0.862 ± 0.156
1.387TrpLys: 1.387 ± 0.235
1.837TrpLeu: 1.837 ± 0.285
0.637TrpMet: 0.637 ± 0.166
0.6TrpAsn: 0.6 ± 0.136
0.375TrpPro: 0.375 ± 0.116
0.487TrpGln: 0.487 ± 0.125
1.274TrpArg: 1.274 ± 0.208
1.124TrpSer: 1.124 ± 0.175
1.237TrpThr: 1.237 ± 0.205
1.087TrpVal: 1.087 ± 0.218
0.487TrpTrp: 0.487 ± 0.17
0.712TrpTyr: 0.712 ± 0.155
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.249TyrAla: 2.249 ± 0.257
0.6TyrCys: 0.6 ± 0.173
2.624TyrAsp: 2.624 ± 0.307
1.987TyrGlu: 1.987 ± 0.301
1.162TyrPhe: 1.162 ± 0.189
2.211TyrGly: 2.211 ± 0.335
0.712TyrHis: 0.712 ± 0.175
1.162TyrIle: 1.162 ± 0.242
1.912TyrLys: 1.912 ± 0.262
2.961TyrLeu: 2.961 ± 0.383
0.487TyrMet: 0.487 ± 0.138
1.537TyrAsn: 1.537 ± 0.22
1.612TyrPro: 1.612 ± 0.267
1.387TyrGln: 1.387 ± 0.188
2.736TyrArg: 2.736 ± 0.325
2.099TyrSer: 2.099 ± 0.272
2.436TyrThr: 2.436 ± 0.266
2.286TyrVal: 2.286 ± 0.278
0.525TyrTrp: 0.525 ± 0.129
0.9TyrTyr: 0.9 ± 0.192
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 158 proteins (26681 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski