Amino acid dipepetide frequency for Hubei tombus-like virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.484AlaAla: 7.484 ± 1.993
0.935AlaCys: 0.935 ± 0.729
4.677AlaAsp: 4.677 ± 1.059
3.742AlaGlu: 3.742 ± 1.409
0.935AlaPhe: 0.935 ± 0.63
3.742AlaGly: 3.742 ± 1.848
3.742AlaHis: 3.742 ± 1.521
2.806AlaIle: 2.806 ± 0.972
2.806AlaLys: 2.806 ± 1.89
8.419AlaLeu: 8.419 ± 2.412
2.806AlaMet: 2.806 ± 0.435
3.742AlaAsn: 3.742 ± 1.848
3.742AlaPro: 3.742 ± 1.848
2.806AlaGln: 2.806 ± 1.161
3.742AlaArg: 3.742 ± 0.949
4.677AlaSer: 4.677 ± 2.129
8.419AlaThr: 8.419 ± 5.685
12.161AlaVal: 12.161 ± 2.761
0.935AlaTrp: 0.935 ± 0.729
8.419AlaTyr: 8.419 ± 3.369
0.0AlaXaa: 0.0 ± 0.0
Cys
0.935CysAla: 0.935 ± 0.729
1.871CysCys: 1.871 ± 0.778
1.871CysAsp: 1.871 ± 0.584
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.871CysGly: 1.871 ± 1.26
0.0CysHis: 0.0 ± 0.0
0.935CysIle: 0.935 ± 0.63
0.935CysLys: 0.935 ± 0.63
4.677CysLeu: 4.677 ± 2.129
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.806CysPro: 2.806 ± 1.161
0.935CysGln: 0.935 ± 0.63
0.935CysArg: 0.935 ± 0.63
1.871CysSer: 1.871 ± 1.26
0.935CysThr: 0.935 ± 0.97
0.935CysVal: 0.935 ± 0.63
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
8.419AspAla: 8.419 ± 2.916
1.871AspCys: 1.871 ± 1.26
1.871AspAsp: 1.871 ± 1.26
0.0AspGlu: 0.0 ± 0.0
0.935AspPhe: 0.935 ± 0.729
3.742AspGly: 3.742 ± 1.168
0.935AspHis: 0.935 ± 0.97
1.871AspIle: 1.871 ± 1.07
2.806AspLys: 2.806 ± 0.972
2.806AspLeu: 2.806 ± 0.972
0.0AspMet: 0.0 ± 0.0
0.935AspAsn: 0.935 ± 0.63
1.871AspPro: 1.871 ± 0.778
0.935AspGln: 0.935 ± 0.97
2.806AspArg: 2.806 ± 1.642
1.871AspSer: 1.871 ± 0.778
0.0AspThr: 0.0 ± 0.0
4.677AspVal: 4.677 ± 0.869
0.0AspTrp: 0.0 ± 0.0
2.806AspTyr: 2.806 ± 1.909
0.0AspXaa: 0.0 ± 0.0
Glu
2.806GluAla: 2.806 ± 1.03
0.0GluCys: 0.0 ± 0.0
3.742GluAsp: 3.742 ± 1.555
3.742GluGlu: 3.742 ± 1.53
4.677GluPhe: 4.677 ± 1.714
2.806GluGly: 2.806 ± 1.03
2.806GluHis: 2.806 ± 1.03
0.935GluIle: 0.935 ± 0.729
6.548GluLys: 6.548 ± 2.52
7.484GluLeu: 7.484 ± 1.567
1.871GluMet: 1.871 ± 1.941
0.0GluAsn: 0.0 ± 0.0
0.935GluPro: 0.935 ± 0.63
0.935GluGln: 0.935 ± 0.63
3.742GluArg: 3.742 ± 1.555
0.935GluSer: 0.935 ± 0.97
0.935GluThr: 0.935 ± 0.63
2.806GluVal: 2.806 ± 1.909
0.0GluTrp: 0.0 ± 0.0
5.613GluTyr: 5.613 ± 2.321
0.0GluXaa: 0.0 ± 0.0
Phe
4.677PheAla: 4.677 ± 0.428
0.935PheCys: 0.935 ± 0.63
1.871PheAsp: 1.871 ± 0.584
2.806PheGlu: 2.806 ± 0.972
1.871PhePhe: 1.871 ± 0.778
3.742PheGly: 3.742 ± 1.168
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
8.419PheLys: 8.419 ± 2.368
0.935PheLeu: 0.935 ± 0.729
0.935PheMet: 0.935 ± 0.63
2.806PheAsn: 2.806 ± 1.553
1.871PhePro: 1.871 ± 1.458
3.742PheGln: 3.742 ± 1.409
1.871PheArg: 1.871 ± 1.26
0.935PheSer: 0.935 ± 0.729
1.871PheThr: 1.871 ± 1.07
0.935PheVal: 0.935 ± 0.63
0.0PheTrp: 0.0 ± 0.0
3.742PheTyr: 3.742 ± 1.521
0.0PheXaa: 0.0 ± 0.0
Gly
6.548GlyAla: 6.548 ± 2.495
0.0GlyCys: 0.0 ± 0.0
3.742GlyAsp: 3.742 ± 1.53
2.806GlyGlu: 2.806 ± 1.161
5.613GlyPhe: 5.613 ± 0.51
1.871GlyGly: 1.871 ± 1.458
0.0GlyHis: 0.0 ± 0.0
3.742GlyIle: 3.742 ± 1.168
4.677GlyLys: 4.677 ± 0.428
5.613GlyLeu: 5.613 ± 1.944
0.0GlyMet: 0.0 ± 0.0
2.806GlyAsn: 2.806 ± 0.471
1.871GlyPro: 1.871 ± 0.584
0.935GlyGln: 0.935 ± 0.97
2.806GlyArg: 2.806 ± 1.89
1.871GlySer: 1.871 ± 0.584
4.677GlyThr: 4.677 ± 2.559
10.29GlyVal: 10.29 ± 1.584
0.0GlyTrp: 0.0 ± 0.0
1.871GlyTyr: 1.871 ± 1.07
0.0GlyXaa: 0.0 ± 0.0
His
0.935HisAla: 0.935 ± 0.63
0.0HisCys: 0.0 ± 0.0
0.935HisAsp: 0.935 ± 0.63
0.935HisGlu: 0.935 ± 0.97
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.935HisLys: 0.935 ± 0.97
3.742HisLeu: 3.742 ± 1.409
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.871HisPro: 1.871 ± 1.26
1.871HisGln: 1.871 ± 1.26
0.935HisArg: 0.935 ± 0.729
1.871HisSer: 1.871 ± 1.26
1.871HisThr: 1.871 ± 0.778
0.935HisVal: 0.935 ± 0.63
0.0HisTrp: 0.0 ± 0.0
0.935HisTyr: 0.935 ± 0.97
0.0HisXaa: 0.0 ± 0.0
Ile
5.613IleAla: 5.613 ± 1.156
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.871IleGlu: 1.871 ± 1.26
0.935IlePhe: 0.935 ± 0.63
0.0IleGly: 0.0 ± 0.0
1.871IleHis: 1.871 ± 0.584
0.935IleIle: 0.935 ± 0.97
3.742IleLys: 3.742 ± 1.53
0.0IleLeu: 0.0 ± 0.0
2.806IleMet: 2.806 ± 0.972
4.677IleAsn: 4.677 ± 1.687
2.806IlePro: 2.806 ± 1.03
1.871IleGln: 1.871 ± 0.584
0.935IleArg: 0.935 ± 0.729
2.806IleSer: 2.806 ± 0.471
2.806IleThr: 2.806 ± 2.186
0.935IleVal: 0.935 ± 0.97
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
6.548LysAla: 6.548 ± 2.113
0.0LysCys: 0.0 ± 0.0
2.806LysAsp: 2.806 ± 1.89
0.935LysGlu: 0.935 ± 0.63
4.677LysPhe: 4.677 ± 2.129
5.613LysGly: 5.613 ± 1.488
0.0LysHis: 0.0 ± 0.0
2.806LysIle: 2.806 ± 0.972
2.806LysLys: 2.806 ± 1.161
4.677LysLeu: 4.677 ± 1.529
0.935LysMet: 0.935 ± 0.729
1.871LysAsn: 1.871 ± 0.584
3.742LysPro: 3.742 ± 0.949
2.806LysGln: 2.806 ± 1.03
8.419LysArg: 8.419 ± 3.369
2.806LysSer: 2.806 ± 1.909
2.806LysThr: 2.806 ± 0.972
0.0LysVal: 0.0 ± 0.0
1.871LysTrp: 1.871 ± 0.778
2.806LysTyr: 2.806 ± 0.972
0.0LysXaa: 0.0 ± 0.0
Leu
2.806LeuAla: 2.806 ± 1.553
1.871LeuCys: 1.871 ± 1.07
4.677LeuAsp: 4.677 ± 1.059
2.806LeuGlu: 2.806 ± 1.642
2.806LeuPhe: 2.806 ± 1.161
2.806LeuGly: 2.806 ± 0.471
0.0LeuHis: 0.0 ± 0.0
1.871LeuIle: 1.871 ± 0.778
3.742LeuLys: 3.742 ± 0.302
2.806LeuLeu: 2.806 ± 1.642
4.677LeuMet: 4.677 ± 1.158
4.677LeuAsn: 4.677 ± 1.714
5.613LeuPro: 5.613 ± 1.156
6.548LeuGln: 6.548 ± 1.063
7.484LeuArg: 7.484 ± 0.685
4.677LeuSer: 4.677 ± 1.474
2.806LeuThr: 2.806 ± 1.89
5.613LeuVal: 5.613 ± 0.51
0.935LeuTrp: 0.935 ± 0.97
2.806LeuTyr: 2.806 ± 1.161
0.0LeuXaa: 0.0 ± 0.0
Met
1.871MetAla: 1.871 ± 1.07
2.806MetCys: 2.806 ± 0.972
0.935MetAsp: 0.935 ± 0.97
2.806MetGlu: 2.806 ± 1.03
0.935MetPhe: 0.935 ± 0.63
1.871MetGly: 1.871 ± 1.26
0.935MetHis: 0.935 ± 0.63
0.935MetIle: 0.935 ± 0.729
0.935MetLys: 0.935 ± 0.63
1.871MetLeu: 1.871 ± 0.778
4.677MetMet: 4.677 ± 0.428
0.935MetAsn: 0.935 ± 0.63
0.0MetPro: 0.0 ± 0.0
1.871MetGln: 1.871 ± 1.941
2.806MetArg: 2.806 ± 1.642
1.871MetSer: 1.871 ± 1.07
2.806MetThr: 2.806 ± 0.972
1.871MetVal: 1.871 ± 0.584
0.0MetTrp: 0.0 ± 0.0
0.935MetTyr: 0.935 ± 0.97
0.0MetXaa: 0.0 ± 0.0
Asn
1.871AsnAla: 1.871 ± 0.584
3.742AsnCys: 3.742 ± 1.53
1.871AsnAsp: 1.871 ± 1.458
2.806AsnGlu: 2.806 ± 1.909
0.935AsnPhe: 0.935 ± 0.97
2.806AsnGly: 2.806 ± 1.161
0.935AsnHis: 0.935 ± 0.63
0.935AsnIle: 0.935 ± 0.729
2.806AsnLys: 2.806 ± 1.161
7.484AsnLeu: 7.484 ± 1.443
0.0AsnMet: 0.0 ± 0.0
3.742AsnAsn: 3.742 ± 0.949
3.742AsnPro: 3.742 ± 0.949
0.935AsnGln: 0.935 ± 0.729
1.871AsnArg: 1.871 ± 0.778
1.871AsnSer: 1.871 ± 0.584
3.742AsnThr: 3.742 ± 1.53
4.677AsnVal: 4.677 ± 1.059
0.935AsnTrp: 0.935 ± 0.63
1.871AsnTyr: 1.871 ± 1.458
0.0AsnXaa: 0.0 ± 0.0
Pro
1.871ProAla: 1.871 ± 0.584
1.871ProCys: 1.871 ± 1.26
0.0ProAsp: 0.0 ± 0.0
3.742ProGlu: 3.742 ± 1.521
0.935ProPhe: 0.935 ± 0.729
4.677ProGly: 4.677 ± 2.559
0.0ProHis: 0.0 ± 0.0
1.871ProIle: 1.871 ± 0.584
1.871ProLys: 1.871 ± 0.584
1.871ProLeu: 1.871 ± 0.584
0.935ProMet: 0.935 ± 0.63
1.871ProAsn: 1.871 ± 1.458
1.871ProPro: 1.871 ± 0.778
1.871ProGln: 1.871 ± 1.941
4.677ProArg: 4.677 ± 2.373
2.806ProSer: 2.806 ± 2.911
3.742ProThr: 3.742 ± 2.177
10.29ProVal: 10.29 ± 2.82
0.935ProTrp: 0.935 ± 0.729
0.935ProTyr: 0.935 ± 0.729
0.0ProXaa: 0.0 ± 0.0
Gln
2.806GlnAla: 2.806 ± 1.553
0.0GlnCys: 0.0 ± 0.0
0.935GlnAsp: 0.935 ± 0.63
0.935GlnGlu: 0.935 ± 0.63
0.935GlnPhe: 0.935 ± 0.729
4.677GlnGly: 4.677 ± 2.939
0.0GlnHis: 0.0 ± 0.0
2.806GlnIle: 2.806 ± 1.89
0.935GlnLys: 0.935 ± 0.63
3.742GlnLeu: 3.742 ± 0.302
0.935GlnMet: 0.935 ± 0.63
3.742GlnAsn: 3.742 ± 0.302
1.871GlnPro: 1.871 ± 0.778
1.871GlnGln: 1.871 ± 0.584
0.935GlnArg: 0.935 ± 0.97
2.806GlnSer: 2.806 ± 0.471
0.935GlnThr: 0.935 ± 0.729
3.742GlnVal: 3.742 ± 1.555
0.935GlnTrp: 0.935 ± 0.63
0.935GlnTyr: 0.935 ± 0.97
0.0GlnXaa: 0.0 ± 0.0
Arg
7.484ArgAla: 7.484 ± 0.605
0.935ArgCys: 0.935 ± 0.63
0.935ArgAsp: 0.935 ± 0.97
8.419ArgGlu: 8.419 ± 3.211
2.806ArgPhe: 2.806 ± 1.909
1.871ArgGly: 1.871 ± 0.778
0.935ArgHis: 0.935 ± 0.97
1.871ArgIle: 1.871 ± 1.458
3.742ArgLys: 3.742 ± 0.949
0.935ArgLeu: 0.935 ± 0.97
3.742ArgMet: 3.742 ± 2.583
2.806ArgAsn: 2.806 ± 1.642
2.806ArgPro: 2.806 ± 1.03
1.871ArgGln: 1.871 ± 1.26
1.871ArgArg: 1.871 ± 1.07
9.355ArgSer: 9.355 ± 2.015
3.742ArgThr: 3.742 ± 1.168
3.742ArgVal: 3.742 ± 1.409
0.935ArgTrp: 0.935 ± 0.97
4.677ArgTyr: 4.677 ± 2.129
0.0ArgXaa: 0.0 ± 0.0
Ser
6.548SerAla: 6.548 ± 0.478
2.806SerCys: 2.806 ± 1.89
0.0SerAsp: 0.0 ± 0.0
1.871SerGlu: 1.871 ± 1.07
5.613SerPhe: 5.613 ± 0.51
5.613SerGly: 5.613 ± 1.156
1.871SerHis: 1.871 ± 0.584
5.613SerIle: 5.613 ± 1.025
1.871SerLys: 1.871 ± 0.584
5.613SerLeu: 5.613 ± 0.51
2.806SerMet: 2.806 ± 1.89
1.871SerAsn: 1.871 ± 1.458
0.935SerPro: 0.935 ± 0.97
0.935SerGln: 0.935 ± 0.729
4.677SerArg: 4.677 ± 1.714
9.355SerSer: 9.355 ± 3.76
4.677SerThr: 4.677 ± 2.566
3.742SerVal: 3.742 ± 0.949
0.0SerTrp: 0.0 ± 0.0
1.871SerTyr: 1.871 ± 1.26
0.0SerXaa: 0.0 ± 0.0
Thr
9.355ThrAla: 9.355 ± 4.475
0.0ThrCys: 0.0 ± 0.0
1.871ThrAsp: 1.871 ± 0.584
0.0ThrGlu: 0.0 ± 0.0
3.742ThrPhe: 3.742 ± 0.949
7.484ThrGly: 7.484 ± 2.836
0.0ThrHis: 0.0 ± 0.0
0.935ThrIle: 0.935 ± 0.729
1.871ThrLys: 1.871 ± 0.584
0.935ThrLeu: 0.935 ± 0.63
1.871ThrMet: 1.871 ± 1.07
2.806ThrAsn: 2.806 ± 1.161
2.806ThrPro: 2.806 ± 1.161
0.935ThrGln: 0.935 ± 0.729
2.806ThrArg: 2.806 ± 0.471
7.484ThrSer: 7.484 ± 2.614
4.677ThrThr: 4.677 ± 3.644
8.419ThrVal: 8.419 ± 1.331
0.0ThrTrp: 0.0 ± 0.0
0.935ThrTyr: 0.935 ± 0.729
0.0ThrXaa: 0.0 ± 0.0
Val
6.548ValAla: 6.548 ± 3.291
0.935ValCys: 0.935 ± 0.729
2.806ValAsp: 2.806 ± 1.03
7.484ValGlu: 7.484 ± 1.054
2.806ValPhe: 2.806 ± 1.161
3.742ValGly: 3.742 ± 1.168
3.742ValHis: 3.742 ± 1.555
3.742ValIle: 3.742 ± 1.168
4.677ValLys: 4.677 ± 1.714
4.677ValLeu: 4.677 ± 0.428
2.806ValMet: 2.806 ± 1.642
8.419ValAsn: 8.419 ± 0.136
7.484ValPro: 7.484 ± 3.938
1.871ValGln: 1.871 ± 1.941
8.419ValArg: 8.419 ± 2.412
5.613ValSer: 5.613 ± 0.51
2.806ValThr: 2.806 ± 2.186
9.355ValVal: 9.355 ± 1.738
0.0ValTrp: 0.0 ± 0.0
0.935ValTyr: 0.935 ± 0.63
0.0ValXaa: 0.0 ± 0.0
Trp
0.935TrpAla: 0.935 ± 0.97
0.0TrpCys: 0.0 ± 0.0
0.935TrpAsp: 0.935 ± 0.97
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.935TrpLys: 0.935 ± 0.63
1.871TrpLeu: 1.871 ± 1.07
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.935TrpGln: 0.935 ± 0.63
0.0TrpArg: 0.0 ± 0.0
1.871TrpSer: 1.871 ± 1.07
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.935TrpTyr: 0.935 ± 0.63
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.613TyrAla: 5.613 ± 1.488
0.935TyrCys: 0.935 ± 0.63
4.677TyrAsp: 4.677 ± 1.687
5.613TyrGlu: 5.613 ± 1.025
2.806TyrPhe: 2.806 ± 1.89
2.806TyrGly: 2.806 ± 0.471
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.871TyrLys: 1.871 ± 0.584
1.871TyrLeu: 1.871 ± 1.26
0.935TyrMet: 0.935 ± 0.729
1.871TyrAsn: 1.871 ± 0.778
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
3.742TyrArg: 3.742 ± 0.949
0.935TyrSer: 0.935 ± 0.63
4.677TyrThr: 4.677 ± 1.625
3.742TyrVal: 3.742 ± 1.168
0.935TyrTrp: 0.935 ± 0.97
2.806TyrTyr: 2.806 ± 1.03
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1070 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski