Amino acid dipepetide frequency for Goose adenovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.807AlaAla: 3.807 ± 0.743
1.066AlaCys: 1.066 ± 0.27
2.436AlaAsp: 2.436 ± 0.497
3.046AlaGlu: 3.046 ± 0.523
2.893AlaPhe: 2.893 ± 0.415
2.589AlaGly: 2.589 ± 0.491
1.37AlaHis: 1.37 ± 0.306
4.188AlaIle: 4.188 ± 0.655
3.274AlaLys: 3.274 ± 0.435
5.33AlaLeu: 5.33 ± 0.718
1.218AlaMet: 1.218 ± 0.314
2.817AlaAsn: 2.817 ± 0.357
3.046AlaPro: 3.046 ± 0.54
2.436AlaGln: 2.436 ± 0.469
2.665AlaArg: 2.665 ± 0.433
4.797AlaSer: 4.797 ± 0.47
3.35AlaThr: 3.35 ± 0.493
3.807AlaVal: 3.807 ± 0.65
0.533AlaTrp: 0.533 ± 0.154
2.436AlaTyr: 2.436 ± 0.498
0.0AlaXaa: 0.0 ± 0.0
Cys
0.685CysAla: 0.685 ± 0.2
0.152CysCys: 0.152 ± 0.095
1.523CysAsp: 1.523 ± 0.379
0.99CysGlu: 0.99 ± 0.243
0.838CysPhe: 0.838 ± 0.299
1.218CysGly: 1.218 ± 0.264
0.533CysHis: 0.533 ± 0.172
1.294CysIle: 1.294 ± 0.287
1.142CysLys: 1.142 ± 0.28
1.218CysLeu: 1.218 ± 0.282
1.066CysMet: 1.066 ± 0.232
1.218CysAsn: 1.218 ± 0.264
1.066CysPro: 1.066 ± 0.208
0.685CysGln: 0.685 ± 0.178
0.609CysArg: 0.609 ± 0.204
2.284CysSer: 2.284 ± 0.343
0.99CysThr: 0.99 ± 0.334
1.142CysVal: 1.142 ± 0.314
0.305CysTrp: 0.305 ± 0.158
0.838CysTyr: 0.838 ± 0.2
0.0CysXaa: 0.0 ± 0.0
Asp
2.817AspAla: 2.817 ± 0.44
1.142AspCys: 1.142 ± 0.261
2.817AspAsp: 2.817 ± 0.447
3.807AspGlu: 3.807 ± 0.481
2.436AspPhe: 2.436 ± 0.328
3.883AspGly: 3.883 ± 0.638
0.99AspHis: 0.99 ± 0.302
3.807AspIle: 3.807 ± 0.691
1.675AspLys: 1.675 ± 0.375
4.797AspLeu: 4.797 ± 0.59
1.294AspMet: 1.294 ± 0.246
1.751AspAsn: 1.751 ± 0.398
4.797AspPro: 4.797 ± 0.771
1.827AspGln: 1.827 ± 0.398
2.817AspArg: 2.817 ± 0.333
4.264AspSer: 4.264 ± 0.546
2.741AspThr: 2.741 ± 0.52
3.578AspVal: 3.578 ± 0.491
1.066AspTrp: 1.066 ± 0.25
2.589AspTyr: 2.589 ± 0.498
0.0AspXaa: 0.0 ± 0.0
Glu
3.655GluAla: 3.655 ± 0.593
1.447GluCys: 1.447 ± 0.31
3.731GluAsp: 3.731 ± 0.417
7.157GluGlu: 7.157 ± 1.511
1.675GluPhe: 1.675 ± 0.432
2.817GluGly: 2.817 ± 0.45
0.838GluHis: 0.838 ± 0.328
3.807GluIle: 3.807 ± 0.392
3.198GluLys: 3.198 ± 0.637
4.264GluLeu: 4.264 ± 0.523
1.675GluMet: 1.675 ± 0.312
2.665GluAsn: 2.665 ± 0.406
1.827GluPro: 1.827 ± 0.417
2.208GluGln: 2.208 ± 0.466
3.883GluArg: 3.883 ± 0.415
4.035GluSer: 4.035 ± 0.452
3.35GluThr: 3.35 ± 0.504
2.893GluVal: 2.893 ± 0.527
0.685GluTrp: 0.685 ± 0.204
2.513GluTyr: 2.513 ± 0.447
0.0GluXaa: 0.0 ± 0.0
Phe
2.589PheAla: 2.589 ± 0.428
0.838PheCys: 0.838 ± 0.236
2.741PheAsp: 2.741 ± 0.432
2.284PheGlu: 2.284 ± 0.43
1.523PhePhe: 1.523 ± 0.328
1.98PheGly: 1.98 ± 0.312
1.294PheHis: 1.294 ± 0.382
2.284PheIle: 2.284 ± 0.289
3.122PheLys: 3.122 ± 0.495
2.893PheLeu: 2.893 ± 0.409
1.827PheMet: 1.827 ± 0.36
3.046PheAsn: 3.046 ± 0.43
1.827PhePro: 1.827 ± 0.342
1.37PheGln: 1.37 ± 0.227
2.893PheArg: 2.893 ± 0.336
3.578PheSer: 3.578 ± 0.399
3.426PheThr: 3.426 ± 0.458
2.513PheVal: 2.513 ± 0.444
0.761PheTrp: 0.761 ± 0.263
2.589PheTyr: 2.589 ± 0.46
0.0PheXaa: 0.0 ± 0.0
Gly
4.34GlyAla: 4.34 ± 0.623
0.685GlyCys: 0.685 ± 0.222
3.198GlyAsp: 3.198 ± 0.438
2.436GlyGlu: 2.436 ± 0.433
2.513GlyPhe: 2.513 ± 0.328
4.721GlyGly: 4.721 ± 0.653
0.761GlyHis: 0.761 ± 0.211
3.883GlyIle: 3.883 ± 0.712
2.741GlyLys: 2.741 ± 0.462
4.492GlyLeu: 4.492 ± 0.646
2.132GlyMet: 2.132 ± 0.411
3.274GlyAsn: 3.274 ± 0.475
2.056GlyPro: 2.056 ± 0.413
1.903GlyGln: 1.903 ± 0.351
3.35GlyArg: 3.35 ± 0.519
5.33GlySer: 5.33 ± 0.858
3.731GlyThr: 3.731 ± 0.667
4.568GlyVal: 4.568 ± 0.74
0.914GlyTrp: 0.914 ± 0.202
2.056GlyTyr: 2.056 ± 0.712
0.0GlyXaa: 0.0 ± 0.0
His
1.37HisAla: 1.37 ± 0.219
0.533HisCys: 0.533 ± 0.157
0.99HisAsp: 0.99 ± 0.254
1.142HisGlu: 1.142 ± 0.331
1.066HisPhe: 1.066 ± 0.224
1.751HisGly: 1.751 ± 0.324
0.914HisHis: 0.914 ± 0.396
1.294HisIle: 1.294 ± 0.278
0.533HisLys: 0.533 ± 0.183
1.37HisLeu: 1.37 ± 0.311
0.228HisMet: 0.228 ± 0.105
1.294HisAsn: 1.294 ± 0.39
1.751HisPro: 1.751 ± 0.388
0.533HisGln: 0.533 ± 0.184
1.37HisArg: 1.37 ± 0.358
1.523HisSer: 1.523 ± 0.328
0.685HisThr: 0.685 ± 0.196
1.447HisVal: 1.447 ± 0.279
0.533HisTrp: 0.533 ± 0.193
0.685HisTyr: 0.685 ± 0.187
0.0HisXaa: 0.0 ± 0.0
Ile
4.188IleAla: 4.188 ± 0.406
1.37IleCys: 1.37 ± 0.257
4.188IleAsp: 4.188 ± 0.641
3.198IleGlu: 3.198 ± 0.5
2.969IlePhe: 2.969 ± 0.57
4.264IleGly: 4.264 ± 0.543
1.066IleHis: 1.066 ± 0.401
2.665IleIle: 2.665 ± 0.621
2.893IleLys: 2.893 ± 0.631
3.883IleLeu: 3.883 ± 0.589
1.294IleMet: 1.294 ± 0.275
3.046IleAsn: 3.046 ± 0.723
4.035IlePro: 4.035 ± 0.564
2.893IleGln: 2.893 ± 0.335
2.969IleArg: 2.969 ± 0.485
4.949IleSer: 4.949 ± 0.508
4.188IleThr: 4.188 ± 0.637
3.35IleVal: 3.35 ± 0.497
0.533IleTrp: 0.533 ± 0.173
2.132IleTyr: 2.132 ± 0.469
0.0IleXaa: 0.0 ± 0.0
Lys
2.284LysAla: 2.284 ± 0.5
1.599LysCys: 1.599 ± 0.438
2.132LysAsp: 2.132 ± 0.408
2.436LysGlu: 2.436 ± 0.435
2.284LysPhe: 2.284 ± 0.318
1.751LysGly: 1.751 ± 0.271
0.838LysHis: 0.838 ± 0.189
2.208LysIle: 2.208 ± 0.515
2.36LysLys: 2.36 ± 0.577
3.502LysLeu: 3.502 ± 0.457
1.827LysMet: 1.827 ± 0.427
2.893LysAsn: 2.893 ± 0.425
2.513LysPro: 2.513 ± 0.391
1.751LysGln: 1.751 ± 0.549
4.721LysArg: 4.721 ± 0.782
4.264LysSer: 4.264 ± 0.732
2.741LysThr: 2.741 ± 0.417
2.284LysVal: 2.284 ± 0.402
0.685LysTrp: 0.685 ± 0.186
2.132LysTyr: 2.132 ± 0.328
0.0LysXaa: 0.0 ± 0.0
Leu
3.426LeuAla: 3.426 ± 0.424
1.675LeuCys: 1.675 ± 0.292
4.34LeuAsp: 4.34 ± 0.652
3.578LeuGlu: 3.578 ± 0.566
3.655LeuPhe: 3.655 ± 0.534
4.264LeuGly: 4.264 ± 0.579
1.98LeuHis: 1.98 ± 0.384
4.264LeuIle: 4.264 ± 0.542
4.035LeuLys: 4.035 ± 0.491
6.624LeuLeu: 6.624 ± 0.641
2.893LeuMet: 2.893 ± 0.487
5.101LeuAsn: 5.101 ± 0.664
3.046LeuPro: 3.046 ± 0.446
3.274LeuGln: 3.274 ± 0.496
4.949LeuArg: 4.949 ± 0.813
6.319LeuSer: 6.319 ± 0.698
5.025LeuThr: 5.025 ± 0.494
4.873LeuVal: 4.873 ± 0.728
1.294LeuTrp: 1.294 ± 0.31
3.122LeuTyr: 3.122 ± 0.529
0.0LeuXaa: 0.0 ± 0.0
Met
2.589MetAla: 2.589 ± 0.387
0.761MetCys: 0.761 ± 0.264
2.132MetAsp: 2.132 ± 0.384
2.284MetGlu: 2.284 ± 0.394
1.142MetPhe: 1.142 ± 0.269
1.827MetGly: 1.827 ± 0.405
0.914MetHis: 0.914 ± 0.32
1.675MetIle: 1.675 ± 0.301
1.523MetLys: 1.523 ± 0.268
1.599MetLeu: 1.599 ± 0.279
1.142MetMet: 1.142 ± 0.354
1.218MetAsn: 1.218 ± 0.248
1.675MetPro: 1.675 ± 0.271
0.609MetGln: 0.609 ± 0.216
2.056MetArg: 2.056 ± 0.373
2.665MetSer: 2.665 ± 0.487
1.37MetThr: 1.37 ± 0.374
2.132MetVal: 2.132 ± 0.454
0.457MetTrp: 0.457 ± 0.146
1.218MetTyr: 1.218 ± 0.243
0.0MetXaa: 0.0 ± 0.0
Asn
3.198AsnAla: 3.198 ± 0.372
0.99AsnCys: 0.99 ± 0.31
2.513AsnAsp: 2.513 ± 0.509
2.969AsnGlu: 2.969 ± 0.421
2.513AsnPhe: 2.513 ± 0.518
4.416AsnGly: 4.416 ± 0.88
1.447AsnHis: 1.447 ± 0.227
3.807AsnIle: 3.807 ± 0.778
1.903AsnLys: 1.903 ± 0.37
4.34AsnLeu: 4.34 ± 0.508
1.599AsnMet: 1.599 ± 0.521
2.208AsnAsn: 2.208 ± 0.393
3.502AsnPro: 3.502 ± 0.556
2.132AsnGln: 2.132 ± 0.401
2.513AsnArg: 2.513 ± 0.437
4.264AsnSer: 4.264 ± 0.784
2.665AsnThr: 2.665 ± 0.399
3.807AsnVal: 3.807 ± 0.763
0.761AsnTrp: 0.761 ± 0.262
2.132AsnTyr: 2.132 ± 0.348
0.0AsnXaa: 0.0 ± 0.0
Pro
3.122ProAla: 3.122 ± 0.525
0.914ProCys: 0.914 ± 0.292
2.132ProAsp: 2.132 ± 0.407
3.122ProGlu: 3.122 ± 0.543
2.665ProPhe: 2.665 ± 0.368
2.208ProGly: 2.208 ± 0.36
1.142ProHis: 1.142 ± 0.267
3.807ProIle: 3.807 ± 0.652
2.284ProLys: 2.284 ± 0.523
3.426ProLeu: 3.426 ± 0.396
1.447ProMet: 1.447 ± 0.336
3.122ProAsn: 3.122 ± 0.48
4.797ProPro: 4.797 ± 0.795
1.675ProGln: 1.675 ± 0.391
3.578ProArg: 3.578 ± 0.565
6.167ProSer: 6.167 ± 0.872
3.274ProThr: 3.274 ± 0.454
3.122ProVal: 3.122 ± 0.544
0.228ProTrp: 0.228 ± 0.141
2.208ProTyr: 2.208 ± 0.375
0.0ProXaa: 0.0 ± 0.0
Gln
1.827GlnAla: 1.827 ± 0.473
0.685GlnCys: 0.685 ± 0.22
1.523GlnAsp: 1.523 ± 0.243
2.36GlnGlu: 2.36 ± 0.41
1.294GlnPhe: 1.294 ± 0.304
1.827GlnGly: 1.827 ± 0.3
0.685GlnHis: 0.685 ± 0.192
1.903GlnIle: 1.903 ± 0.378
0.99GlnLys: 0.99 ± 0.24
4.568GlnLeu: 4.568 ± 0.751
1.142GlnMet: 1.142 ± 0.305
2.436GlnAsn: 2.436 ± 0.442
2.132GlnPro: 2.132 ± 0.528
2.208GlnGln: 2.208 ± 0.412
2.208GlnArg: 2.208 ± 0.545
3.198GlnSer: 3.198 ± 0.431
1.98GlnThr: 1.98 ± 0.455
1.599GlnVal: 1.599 ± 0.349
0.457GlnTrp: 0.457 ± 0.139
1.523GlnTyr: 1.523 ± 0.304
0.0GlnXaa: 0.0 ± 0.0
Arg
3.122ArgAla: 3.122 ± 0.65
1.294ArgCys: 1.294 ± 0.356
3.198ArgAsp: 3.198 ± 0.449
2.817ArgGlu: 2.817 ± 0.619
3.731ArgPhe: 3.731 ± 0.603
2.817ArgGly: 2.817 ± 0.597
1.523ArgHis: 1.523 ± 0.295
3.502ArgIle: 3.502 ± 0.662
2.817ArgLys: 2.817 ± 0.469
4.492ArgLeu: 4.492 ± 0.627
1.751ArgMet: 1.751 ± 0.321
2.893ArgAsn: 2.893 ± 0.668
2.741ArgPro: 2.741 ± 0.53
2.132ArgGln: 2.132 ± 0.413
4.873ArgArg: 4.873 ± 1.523
4.797ArgSer: 4.797 ± 0.552
4.264ArgThr: 4.264 ± 0.607
4.035ArgVal: 4.035 ± 0.602
1.218ArgTrp: 1.218 ± 0.279
1.675ArgTyr: 1.675 ± 0.294
0.0ArgXaa: 0.0 ± 0.0
Ser
3.502SerAla: 3.502 ± 0.587
1.599SerCys: 1.599 ± 0.335
5.33SerAsp: 5.33 ± 0.762
6.015SerGlu: 6.015 ± 0.643
3.35SerPhe: 3.35 ± 0.471
5.71SerGly: 5.71 ± 0.82
1.523SerHis: 1.523 ± 0.387
5.71SerIle: 5.71 ± 0.726
3.502SerLys: 3.502 ± 0.505
7.69SerLeu: 7.69 ± 0.867
1.903SerMet: 1.903 ± 0.43
4.721SerAsn: 4.721 ± 0.535
3.959SerPro: 3.959 ± 0.56
2.436SerGln: 2.436 ± 0.383
5.101SerArg: 5.101 ± 0.588
9.746SerSer: 9.746 ± 1.335
5.863SerThr: 5.863 ± 0.53
6.7SerVal: 6.7 ± 0.778
1.142SerTrp: 1.142 ± 0.264
2.665SerTyr: 2.665 ± 0.403
0.0SerXaa: 0.0 ± 0.0
Thr
3.959ThrAla: 3.959 ± 0.442
0.533ThrCys: 0.533 ± 0.162
2.741ThrAsp: 2.741 ± 0.52
2.969ThrGlu: 2.969 ± 0.49
2.056ThrPhe: 2.056 ± 0.374
3.655ThrGly: 3.655 ± 0.538
0.761ThrHis: 0.761 ± 0.218
3.731ThrIle: 3.731 ± 0.66
2.741ThrLys: 2.741 ± 0.357
4.568ThrLeu: 4.568 ± 0.597
2.056ThrMet: 2.056 ± 0.359
3.655ThrAsn: 3.655 ± 0.772
3.959ThrPro: 3.959 ± 0.59
2.513ThrGln: 2.513 ± 0.361
2.817ThrArg: 2.817 ± 0.444
6.091ThrSer: 6.091 ± 0.892
4.568ThrThr: 4.568 ± 0.937
3.807ThrVal: 3.807 ± 0.437
0.761ThrTrp: 0.761 ± 0.194
1.675ThrTyr: 1.675 ± 0.328
0.0ThrXaa: 0.0 ± 0.0
Val
3.35ValAla: 3.35 ± 0.503
1.523ValCys: 1.523 ± 0.334
3.807ValAsp: 3.807 ± 0.519
2.969ValGlu: 2.969 ± 0.563
3.883ValPhe: 3.883 ± 0.462
3.578ValGly: 3.578 ± 0.636
1.294ValHis: 1.294 ± 0.332
3.578ValIle: 3.578 ± 0.484
3.122ValLys: 3.122 ± 0.561
5.101ValLeu: 5.101 ± 0.848
1.751ValMet: 1.751 ± 0.292
3.655ValAsn: 3.655 ± 0.569
3.198ValPro: 3.198 ± 0.591
2.665ValGln: 2.665 ± 0.533
3.426ValArg: 3.426 ± 0.388
5.863ValSer: 5.863 ± 0.69
3.046ValThr: 3.046 ± 0.509
4.492ValVal: 4.492 ± 0.654
0.533ValTrp: 0.533 ± 0.171
2.665ValTyr: 2.665 ± 0.474
0.0ValXaa: 0.0 ± 0.0
Trp
0.838TrpAla: 0.838 ± 0.23
0.228TrpCys: 0.228 ± 0.134
0.609TrpAsp: 0.609 ± 0.169
0.457TrpGlu: 0.457 ± 0.178
0.381TrpPhe: 0.381 ± 0.182
1.066TrpGly: 1.066 ± 0.3
0.152TrpHis: 0.152 ± 0.096
0.685TrpIle: 0.685 ± 0.248
0.914TrpLys: 0.914 ± 0.301
0.609TrpLeu: 0.609 ± 0.19
0.609TrpMet: 0.609 ± 0.191
0.685TrpAsn: 0.685 ± 0.164
0.457TrpPro: 0.457 ± 0.298
0.533TrpGln: 0.533 ± 0.324
1.066TrpArg: 1.066 ± 0.312
1.294TrpSer: 1.294 ± 0.37
0.99TrpThr: 0.99 ± 0.251
0.914TrpVal: 0.914 ± 0.222
0.305TrpTrp: 0.305 ± 0.16
0.838TrpTyr: 0.838 ± 0.234
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.436TyrAla: 2.436 ± 0.405
0.761TyrCys: 0.761 ± 0.23
2.817TyrAsp: 2.817 ± 0.566
2.284TyrGlu: 2.284 ± 0.502
2.513TyrPhe: 2.513 ± 0.588
2.741TyrGly: 2.741 ± 0.468
0.99TyrHis: 0.99 ± 0.252
1.98TyrIle: 1.98 ± 0.338
2.436TyrLys: 2.436 ± 0.49
2.969TyrLeu: 2.969 ± 0.441
2.056TyrMet: 2.056 ± 0.446
1.98TyrAsn: 1.98 ± 0.348
2.056TyrPro: 2.056 ± 0.339
0.838TyrGln: 0.838 ± 0.21
1.827TyrArg: 1.827 ± 0.387
2.741TyrSer: 2.741 ± 0.457
1.37TyrThr: 1.37 ± 0.425
2.436TyrVal: 2.436 ± 0.345
0.457TyrTrp: 0.457 ± 0.284
1.447TyrTyr: 1.447 ± 0.331
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (13135 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski