Amino acid dipepetide frequency for Coccinia mosaic Virudhunagar virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.965AlaAla: 1.965 ± 1.212
1.965AlaCys: 1.965 ± 0.876
3.929AlaAsp: 3.929 ± 1.023
1.965AlaGlu: 1.965 ± 1.202
3.929AlaPhe: 3.929 ± 1.469
1.965AlaGly: 1.965 ± 0.886
2.947AlaHis: 2.947 ± 1.055
0.982AlaIle: 0.982 ± 0.871
0.982AlaLys: 0.982 ± 1.017
6.876AlaLeu: 6.876 ± 3.198
0.0AlaMet: 0.0 ± 0.0
0.982AlaAsn: 0.982 ± 0.69
2.947AlaPro: 2.947 ± 2.252
2.947AlaGln: 2.947 ± 1.311
5.894AlaArg: 5.894 ± 1.868
5.894AlaSer: 5.894 ± 1.83
5.894AlaThr: 5.894 ± 2.34
4.912AlaVal: 4.912 ± 1.79
1.965AlaTrp: 1.965 ± 2.001
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.965CysAla: 1.965 ± 1.84
0.982CysCys: 0.982 ± 1.017
0.0CysAsp: 0.0 ± 0.0
0.982CysGlu: 0.982 ± 0.69
1.965CysPhe: 1.965 ± 1.456
1.965CysGly: 1.965 ± 1.061
0.982CysHis: 0.982 ± 0.871
0.0CysIle: 0.0 ± 0.0
0.982CysLys: 0.982 ± 0.69
1.965CysLeu: 1.965 ± 1.84
0.982CysMet: 0.982 ± 1.017
1.965CysAsn: 1.965 ± 1.061
2.947CysPro: 2.947 ± 3.052
0.0CysGln: 0.0 ± 0.0
0.982CysArg: 0.982 ± 0.69
1.965CysSer: 1.965 ± 1.31
1.965CysThr: 1.965 ± 1.388
2.947CysVal: 2.947 ± 1.28
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.965AspAla: 1.965 ± 1.061
0.982AspCys: 0.982 ± 0.871
1.965AspAsp: 1.965 ± 1.179
0.982AspGlu: 0.982 ± 0.69
0.982AspPhe: 0.982 ± 0.69
0.982AspGly: 0.982 ± 0.871
2.947AspHis: 2.947 ± 1.786
2.947AspIle: 2.947 ± 1.498
0.982AspLys: 0.982 ± 0.69
6.876AspLeu: 6.876 ± 2.357
1.965AspMet: 1.965 ± 1.056
3.929AspAsn: 3.929 ± 1.632
2.947AspPro: 2.947 ± 1.416
0.0AspGln: 0.0 ± 0.0
4.912AspArg: 4.912 ± 1.635
2.947AspSer: 2.947 ± 1.163
3.929AspThr: 3.929 ± 2.499
4.912AspVal: 4.912 ± 2.061
1.965AspTrp: 1.965 ± 1.061
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.965GluAla: 1.965 ± 1.069
0.0GluCys: 0.0 ± 0.0
0.982GluAsp: 0.982 ± 0.92
5.894GluGlu: 5.894 ± 2.67
1.965GluPhe: 1.965 ± 1.292
3.929GluGly: 3.929 ± 1.169
0.982GluHis: 0.982 ± 0.92
2.947GluIle: 2.947 ± 1.889
1.965GluLys: 1.965 ± 1.292
1.965GluLeu: 1.965 ± 1.362
0.0GluMet: 0.0 ± 0.0
3.929GluAsn: 3.929 ± 2.29
0.982GluPro: 0.982 ± 0.69
2.947GluGln: 2.947 ± 1.33
0.982GluArg: 0.982 ± 0.92
2.947GluSer: 2.947 ± 1.07
1.965GluThr: 1.965 ± 1.388
2.947GluVal: 2.947 ± 1.275
0.982GluTrp: 0.982 ± 0.871
2.947GluTyr: 2.947 ± 1.208
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.982PheCys: 0.982 ± 0.69
1.965PheAsp: 1.965 ± 1.38
1.965PheGlu: 1.965 ± 0.886
1.965PhePhe: 1.965 ± 0.886
0.982PheGly: 0.982 ± 0.69
0.0PheHis: 0.0 ± 0.0
2.947PheIle: 2.947 ± 1.487
1.965PheLys: 1.965 ± 1.327
4.912PheLeu: 4.912 ± 1.951
0.982PheMet: 0.982 ± 1.0
3.929PheAsn: 3.929 ± 1.373
0.982PhePro: 0.982 ± 1.017
0.982PheGln: 0.982 ± 0.871
3.929PheArg: 3.929 ± 1.626
2.947PheSer: 2.947 ± 1.575
2.947PheThr: 2.947 ± 1.866
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.982PheTyr: 0.982 ± 0.69
0.0PheXaa: 0.0 ± 0.0
Gly
2.947GlyAla: 2.947 ± 2.124
1.965GlyCys: 1.965 ± 0.886
0.982GlyAsp: 0.982 ± 0.92
1.965GlyGlu: 1.965 ± 1.213
0.982GlyPhe: 0.982 ± 0.871
3.929GlyGly: 3.929 ± 2.091
2.947GlyHis: 2.947 ± 1.259
2.947GlyIle: 2.947 ± 1.664
5.894GlyLys: 5.894 ± 2.788
7.859GlyLeu: 7.859 ± 2.403
0.982GlyMet: 0.982 ± 1.017
0.982GlyAsn: 0.982 ± 1.0
6.876GlyPro: 6.876 ± 3.776
0.982GlyGln: 0.982 ± 1.017
1.965GlyArg: 1.965 ± 1.84
0.982GlySer: 0.982 ± 0.92
5.894GlyThr: 5.894 ± 1.876
2.947GlyVal: 2.947 ± 2.03
0.0GlyTrp: 0.0 ± 0.0
0.982GlyTyr: 0.982 ± 1.017
0.0GlyXaa: 0.0 ± 0.0
His
3.929HisAla: 3.929 ± 1.768
1.965HisCys: 1.965 ± 1.31
2.947HisAsp: 2.947 ± 0.936
0.982HisGlu: 0.982 ± 1.017
1.965HisPhe: 1.965 ± 1.292
3.929HisGly: 3.929 ± 2.016
3.929HisHis: 3.929 ± 2.01
1.965HisIle: 1.965 ± 1.212
2.947HisLys: 2.947 ± 1.499
2.947HisLeu: 2.947 ± 2.001
0.0HisMet: 0.0 ± 0.0
2.947HisAsn: 2.947 ± 1.208
0.982HisPro: 0.982 ± 0.92
0.0HisGln: 0.0 ± 0.0
4.912HisArg: 4.912 ± 1.573
1.965HisSer: 1.965 ± 1.186
2.947HisThr: 2.947 ± 1.504
5.894HisVal: 5.894 ± 4.575
0.0HisTrp: 0.0 ± 0.0
0.982HisTyr: 0.982 ± 1.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.982IleAla: 0.982 ± 1.016
0.982IleCys: 0.982 ± 0.92
3.929IleAsp: 3.929 ± 1.529
1.965IleGlu: 1.965 ± 1.327
0.982IlePhe: 0.982 ± 1.0
1.965IleGly: 1.965 ± 0.876
1.965IleHis: 1.965 ± 1.159
2.947IleIle: 2.947 ± 1.698
3.929IleLys: 3.929 ± 1.529
2.947IleLeu: 2.947 ± 1.944
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
0.982IlePro: 0.982 ± 1.0
2.947IleGln: 2.947 ± 1.866
4.912IleArg: 4.912 ± 1.806
1.965IleSer: 1.965 ± 1.082
5.894IleThr: 5.894 ± 3.073
0.982IleVal: 0.982 ± 0.69
1.965IleTrp: 1.965 ± 1.202
2.947IleTyr: 2.947 ± 1.699
0.0IleXaa: 0.0 ± 0.0
Lys
4.912LysAla: 4.912 ± 1.403
1.965LysCys: 1.965 ± 1.159
0.0LysAsp: 0.0 ± 0.0
1.965LysGlu: 1.965 ± 1.287
1.965LysPhe: 1.965 ± 0.886
2.947LysGly: 2.947 ± 2.1
2.947LysHis: 2.947 ± 2.001
2.947LysIle: 2.947 ± 1.487
0.0LysLys: 0.0 ± 0.0
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
4.912LysAsn: 4.912 ± 2.332
2.947LysPro: 2.947 ± 1.699
0.0LysGln: 0.0 ± 0.0
2.947LysArg: 2.947 ± 1.327
2.947LysSer: 2.947 ± 1.615
2.947LysThr: 2.947 ± 1.172
4.912LysVal: 4.912 ± 2.056
0.982LysTrp: 0.982 ± 0.69
3.929LysTyr: 3.929 ± 1.169
0.0LysXaa: 0.0 ± 0.0
Leu
3.929LeuAla: 3.929 ± 2.016
4.912LeuCys: 4.912 ± 2.009
5.894LeuAsp: 5.894 ± 2.782
4.912LeuGlu: 4.912 ± 2.009
3.929LeuPhe: 3.929 ± 1.398
3.929LeuGly: 3.929 ± 1.023
1.965LeuHis: 1.965 ± 1.25
1.965LeuIle: 1.965 ± 1.362
5.894LeuLys: 5.894 ± 2.792
1.965LeuLeu: 1.965 ± 1.362
1.965LeuMet: 1.965 ± 1.082
1.965LeuAsn: 1.965 ± 0.886
2.947LeuPro: 2.947 ± 1.429
3.929LeuGln: 3.929 ± 2.192
5.894LeuArg: 5.894 ± 2.242
3.929LeuSer: 3.929 ± 2.144
4.912LeuThr: 4.912 ± 1.947
6.876LeuVal: 6.876 ± 2.634
0.982LeuTrp: 0.982 ± 0.871
3.929LeuTyr: 3.929 ± 1.378
0.0LeuXaa: 0.0 ± 0.0
Met
0.982MetAla: 0.982 ± 0.69
0.982MetCys: 0.982 ± 0.69
2.947MetAsp: 2.947 ± 1.498
0.0MetGlu: 0.0 ± 0.0
2.947MetPhe: 2.947 ± 2.069
3.929MetGly: 3.929 ± 1.494
2.947MetHis: 2.947 ± 0.936
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.947MetLeu: 2.947 ± 1.172
0.982MetMet: 0.982 ± 1.016
0.982MetAsn: 0.982 ± 0.69
0.982MetPro: 0.982 ± 0.92
0.0MetGln: 0.0 ± 0.0
0.982MetArg: 0.982 ± 1.016
2.947MetSer: 2.947 ± 1.23
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.965MetTrp: 1.965 ± 1.292
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.912AsnAla: 4.912 ± 1.997
0.982AsnCys: 0.982 ± 0.92
0.982AsnAsp: 0.982 ± 1.0
0.982AsnGlu: 0.982 ± 0.69
0.982AsnPhe: 0.982 ± 0.69
1.965AsnGly: 1.965 ± 1.202
2.947AsnHis: 2.947 ± 1.698
0.982AsnIle: 0.982 ± 0.69
0.982AsnLys: 0.982 ± 0.92
1.965AsnLeu: 1.965 ± 1.159
3.929AsnMet: 3.929 ± 1.78
2.947AsnAsn: 2.947 ± 1.615
3.929AsnPro: 3.929 ± 2.226
2.947AsnGln: 2.947 ± 1.07
5.894AsnArg: 5.894 ± 1.715
0.982AsnSer: 0.982 ± 0.871
1.965AsnThr: 1.965 ± 1.212
4.912AsnVal: 4.912 ± 2.522
0.0AsnTrp: 0.0 ± 0.0
2.947AsnTyr: 2.947 ± 1.33
0.0AsnXaa: 0.0 ± 0.0
Pro
3.929ProAla: 3.929 ± 1.466
2.947ProCys: 2.947 ± 1.055
3.929ProAsp: 3.929 ± 2.037
1.965ProGlu: 1.965 ± 1.061
0.0ProPhe: 0.0 ± 0.0
3.929ProGly: 3.929 ± 2.837
2.947ProHis: 2.947 ± 1.416
2.947ProIle: 2.947 ± 1.28
0.982ProLys: 0.982 ± 1.0
3.929ProLeu: 3.929 ± 1.413
1.965ProMet: 1.965 ± 1.065
2.947ProAsn: 2.947 ± 1.451
2.947ProPro: 2.947 ± 2.252
2.947ProGln: 2.947 ± 1.163
3.929ProArg: 3.929 ± 1.408
7.859ProSer: 7.859 ± 2.645
5.894ProThr: 5.894 ± 1.812
3.929ProVal: 3.929 ± 1.834
0.982ProTrp: 0.982 ± 0.92
1.965ProTyr: 1.965 ± 0.876
0.0ProXaa: 0.0 ± 0.0
Gln
4.912GlnAla: 4.912 ± 2.184
0.0GlnCys: 0.0 ± 0.0
4.912GlnAsp: 4.912 ± 1.79
2.947GlnGlu: 2.947 ± 1.33
0.0GlnPhe: 0.0 ± 0.0
1.965GlnGly: 1.965 ± 1.061
1.965GlnHis: 1.965 ± 1.186
1.965GlnIle: 1.965 ± 1.159
0.982GlnLys: 0.982 ± 1.017
0.982GlnLeu: 0.982 ± 1.016
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.929GlnPro: 3.929 ± 1.796
3.929GlnGln: 3.929 ± 1.626
1.965GlnArg: 1.965 ± 1.179
2.947GlnSer: 2.947 ± 1.487
2.947GlnThr: 2.947 ± 1.613
1.965GlnVal: 1.965 ± 0.886
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.894ArgAla: 5.894 ± 1.538
1.965ArgCys: 1.965 ± 1.25
3.929ArgAsp: 3.929 ± 1.679
2.947ArgGlu: 2.947 ± 1.228
1.965ArgPhe: 1.965 ± 1.213
4.912ArgGly: 4.912 ± 1.635
2.947ArgHis: 2.947 ± 1.055
3.929ArgIle: 3.929 ± 1.14
3.929ArgLys: 3.929 ± 1.921
5.894ArgLeu: 5.894 ± 3.344
1.965ArgMet: 1.965 ± 0.867
0.982ArgAsn: 0.982 ± 0.871
8.841ArgPro: 8.841 ± 2.617
2.947ArgGln: 2.947 ± 2.176
7.859ArgArg: 7.859 ± 2.631
3.929ArgSer: 3.929 ± 1.107
3.929ArgThr: 3.929 ± 2.274
5.894ArgVal: 5.894 ± 2.087
0.0ArgTrp: 0.0 ± 0.0
1.965ArgTyr: 1.965 ± 1.069
0.0ArgXaa: 0.0 ± 0.0
Ser
1.965SerAla: 1.965 ± 1.186
0.982SerCys: 0.982 ± 1.017
2.947SerAsp: 2.947 ± 0.936
1.965SerGlu: 1.965 ± 1.362
1.965SerPhe: 1.965 ± 1.213
0.982SerGly: 0.982 ± 1.0
0.982SerHis: 0.982 ± 1.016
2.947SerIle: 2.947 ± 1.866
4.912SerLys: 4.912 ± 1.573
2.947SerLeu: 2.947 ± 1.242
1.965SerMet: 1.965 ± 2.248
5.894SerAsn: 5.894 ± 2.97
6.876SerPro: 6.876 ± 2.244
2.947SerGln: 2.947 ± 1.256
6.876SerArg: 6.876 ± 3.136
8.841SerSer: 8.841 ± 4.103
6.876SerThr: 6.876 ± 3.168
4.912SerVal: 4.912 ± 1.591
0.0SerTrp: 0.0 ± 0.0
1.965SerTyr: 1.965 ± 1.061
0.0SerXaa: 0.0 ± 0.0
Thr
3.929ThrAla: 3.929 ± 1.016
0.0ThrCys: 0.0 ± 0.0
0.982ThrAsp: 0.982 ± 1.007
2.947ThrGlu: 2.947 ± 0.936
0.0ThrPhe: 0.0 ± 0.0
6.876ThrGly: 6.876 ± 2.047
3.929ThrHis: 3.929 ± 1.454
1.965ThrIle: 1.965 ± 1.327
3.929ThrLys: 3.929 ± 1.454
5.894ThrLeu: 5.894 ± 2.84
0.982ThrMet: 0.982 ± 0.92
2.947ThrAsn: 2.947 ± 1.659
4.912ThrPro: 4.912 ± 1.112
4.912ThrGln: 4.912 ± 2.229
2.947ThrArg: 2.947 ± 1.659
6.876ThrSer: 6.876 ± 4.399
0.0ThrThr: 0.0 ± 0.0
6.876ThrVal: 6.876 ± 2.596
0.982ThrTrp: 0.982 ± 1.007
3.929ThrTyr: 3.929 ± 1.373
0.0ThrXaa: 0.0 ± 0.0
Val
0.982ValAla: 0.982 ± 0.69
0.982ValCys: 0.982 ± 1.016
3.929ValAsp: 3.929 ± 1.74
3.929ValGlu: 3.929 ± 2.499
3.929ValPhe: 3.929 ± 1.658
2.947ValGly: 2.947 ± 1.055
5.894ValHis: 5.894 ± 2.685
4.912ValIle: 4.912 ± 1.877
3.929ValLys: 3.929 ± 1.272
5.894ValLeu: 5.894 ± 1.873
3.929ValMet: 3.929 ± 1.271
2.947ValAsn: 2.947 ± 1.23
3.929ValPro: 3.929 ± 1.521
0.982ValGln: 0.982 ± 0.69
6.876ValArg: 6.876 ± 2.596
2.947ValSer: 2.947 ± 1.327
2.947ValThr: 2.947 ± 1.28
4.912ValVal: 4.912 ± 1.095
2.947ValTrp: 2.947 ± 1.698
4.912ValTyr: 4.912 ± 2.149
0.0ValXaa: 0.0 ± 0.0
Trp
3.929TrpAla: 3.929 ± 2.091
0.0TrpCys: 0.0 ± 0.0
0.982TrpAsp: 0.982 ± 1.017
0.0TrpGlu: 0.0 ± 0.0
0.982TrpPhe: 0.982 ± 0.871
0.0TrpGly: 0.0 ± 0.0
0.982TrpHis: 0.982 ± 0.69
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.982TrpLeu: 0.982 ± 1.007
0.982TrpMet: 0.982 ± 0.69
0.982TrpAsn: 0.982 ± 0.871
0.0TrpPro: 0.0 ± 0.0
0.982TrpGln: 0.982 ± 1.0
0.982TrpArg: 0.982 ± 0.871
0.0TrpSer: 0.0 ± 0.0
1.965TrpThr: 1.965 ± 2.014
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.965TrpTyr: 1.965 ± 1.287
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.947TyrAla: 2.947 ± 2.069
0.0TyrCys: 0.0 ± 0.0
0.982TyrAsp: 0.982 ± 0.69
1.965TyrGlu: 1.965 ± 1.069
1.965TyrPhe: 1.965 ± 1.213
0.982TyrGly: 0.982 ± 1.0
0.982TyrHis: 0.982 ± 1.017
2.947TyrIle: 2.947 ± 1.415
0.982TyrLys: 0.982 ± 1.007
6.876TyrLeu: 6.876 ± 2.754
1.965TyrMet: 1.965 ± 0.829
1.965TyrAsn: 1.965 ± 1.212
0.982TyrPro: 0.982 ± 0.92
0.982TyrGln: 0.982 ± 0.69
0.982TyrArg: 0.982 ± 0.69
4.912TyrSer: 4.912 ± 2.158
0.0TyrThr: 0.0 ± 0.0
3.929TyrVal: 3.929 ± 1.408
0.0TyrTrp: 0.0 ± 0.0
1.965TyrTyr: 1.965 ± 1.741
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1019 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski