Amino acid dipepetide frequency for Odontoglossum ringspot virus (isolate Singapore 1) (ORSV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.455AlaAla: 3.455 ± 0.625
1.256AlaCys: 1.256 ± 0.344
4.397AlaAsp: 4.397 ± 0.836
5.967AlaGlu: 5.967 ± 1.47
2.513AlaPhe: 2.513 ± 0.879
4.083AlaGly: 4.083 ± 0.841
1.57AlaHis: 1.57 ± 0.391
1.884AlaIle: 1.884 ± 1.228
1.884AlaLys: 1.884 ± 0.526
6.91AlaLeu: 6.91 ± 0.888
2.198AlaMet: 2.198 ± 0.541
1.884AlaAsn: 1.884 ± 0.248
1.884AlaPro: 1.884 ± 0.502
1.256AlaGln: 1.256 ± 0.344
2.513AlaArg: 2.513 ± 0.557
1.884AlaSer: 1.884 ± 0.248
4.083AlaThr: 4.083 ± 0.953
6.595AlaVal: 6.595 ± 0.688
1.57AlaTrp: 1.57 ± 0.48
1.57AlaTyr: 1.57 ± 0.531
0.0AlaXaa: 0.0 ± 0.0
Cys
1.256CysAla: 1.256 ± 0.44
1.256CysCys: 1.256 ± 0.334
1.57CysAsp: 1.57 ± 0.391
0.942CysGlu: 0.942 ± 0.416
0.0CysPhe: 0.0 ± 0.0
1.884CysGly: 1.884 ± 0.526
0.628CysHis: 0.628 ± 0.167
0.0CysIle: 0.0 ± 0.0
3.455CysLys: 3.455 ± 0.56
3.141CysLeu: 3.141 ± 0.576
0.628CysMet: 0.628 ± 0.167
0.0CysAsn: 0.0 ± 0.0
1.256CysPro: 1.256 ± 0.344
0.0CysGln: 0.0 ± 0.0
0.628CysArg: 0.628 ± 0.167
1.256CysSer: 1.256 ± 0.344
1.884CysThr: 1.884 ± 0.441
0.942CysVal: 0.942 ± 0.416
0.0CysTrp: 0.0 ± 0.0
0.628CysTyr: 0.628 ± 0.167
0.0CysXaa: 0.0 ± 0.0
Asp
6.281AspAla: 6.281 ± 0.717
1.256AspCys: 1.256 ± 0.344
2.198AspAsp: 2.198 ± 1.643
5.967AspGlu: 5.967 ± 0.959
2.827AspPhe: 2.827 ± 0.79
3.141AspGly: 3.141 ± 0.836
0.314AspHis: 0.314 ± 0.203
5.653AspIle: 5.653 ± 0.743
5.339AspLys: 5.339 ± 0.504
4.711AspLeu: 4.711 ± 0.746
2.827AspMet: 2.827 ± 0.699
1.57AspAsn: 1.57 ± 0.341
3.769AspPro: 3.769 ± 2.218
0.942AspGln: 0.942 ± 0.263
1.57AspArg: 1.57 ± 0.391
4.397AspSer: 4.397 ± 0.916
3.141AspThr: 3.141 ± 0.358
6.91AspVal: 6.91 ± 0.745
0.628AspTrp: 0.628 ± 0.167
1.57AspTyr: 1.57 ± 0.391
0.0AspXaa: 0.0 ± 0.0
Glu
5.025GluAla: 5.025 ± 0.49
0.628GluCys: 0.628 ± 0.167
2.198GluAsp: 2.198 ± 0.541
3.141GluGlu: 3.141 ± 0.783
4.397GluPhe: 4.397 ± 0.916
0.942GluGly: 0.942 ± 0.416
0.628GluHis: 0.628 ± 0.167
3.141GluIle: 3.141 ± 0.836
4.397GluLys: 4.397 ± 1.473
6.91GluLeu: 6.91 ± 0.702
0.314GluMet: 0.314 ± 0.535
2.827GluAsn: 2.827 ± 1.515
0.942GluPro: 0.942 ± 0.416
2.827GluGln: 2.827 ± 0.699
4.397GluArg: 4.397 ± 1.082
3.455GluSer: 3.455 ± 0.53
2.513GluThr: 2.513 ± 0.987
3.769GluVal: 3.769 ± 0.678
1.57GluTrp: 1.57 ± 0.341
3.455GluTyr: 3.455 ± 0.905
0.0GluXaa: 0.0 ± 0.0
Phe
0.628PheAla: 0.628 ± 0.574
2.513PheCys: 2.513 ± 0.446
3.455PheAsp: 3.455 ± 0.33
2.513PheGlu: 2.513 ± 0.46
2.513PhePhe: 2.513 ± 0.646
3.141PheGly: 3.141 ± 0.783
1.884PheHis: 1.884 ± 0.526
2.513PheIle: 2.513 ± 0.245
2.513PheLys: 2.513 ± 0.245
3.455PheLeu: 3.455 ± 0.575
1.256PheMet: 1.256 ± 0.334
1.884PheAsn: 1.884 ± 0.526
4.397PhePro: 4.397 ± 0.521
3.455PheGln: 3.455 ± 0.669
3.141PheArg: 3.141 ± 0.358
3.141PheSer: 3.141 ± 0.445
1.884PheThr: 1.884 ± 0.248
4.397PheVal: 4.397 ± 1.473
1.57PheTrp: 1.57 ± 0.391
2.198PheTyr: 2.198 ± 0.541
0.0PheXaa: 0.0 ± 0.0
Gly
2.827GlyAla: 2.827 ± 0.508
1.57GlyCys: 1.57 ± 0.391
4.083GlyAsp: 4.083 ± 0.503
3.769GlyGlu: 3.769 ± 0.475
1.884GlyPhe: 1.884 ± 0.248
2.827GlyGly: 2.827 ± 0.633
0.942GlyHis: 0.942 ± 0.263
1.884GlyIle: 1.884 ± 0.819
5.967GlyLys: 5.967 ± 1.132
5.967GlyLeu: 5.967 ± 0.258
1.256GlyMet: 1.256 ± 0.505
2.198GlyAsn: 2.198 ± 0.683
1.256GlyPro: 1.256 ± 0.344
0.628GlyGln: 0.628 ± 0.407
1.884GlyArg: 1.884 ± 0.248
2.513GlySer: 2.513 ± 0.446
0.628GlyThr: 0.628 ± 1.209
5.025GlyVal: 5.025 ± 1.485
0.0GlyTrp: 0.0 ± 0.0
1.884GlyTyr: 1.884 ± 0.658
0.0GlyXaa: 0.0 ± 0.0
His
0.628HisAla: 0.628 ± 0.167
1.57HisCys: 1.57 ± 0.391
0.314HisAsp: 0.314 ± 0.203
0.628HisGlu: 0.628 ± 0.167
2.513HisPhe: 2.513 ± 0.669
0.0HisGly: 0.0 ± 0.0
0.314HisHis: 0.314 ± 0.203
2.198HisIle: 2.198 ± 0.541
0.942HisLys: 0.942 ± 0.263
2.827HisLeu: 2.827 ± 0.699
0.314HisMet: 0.314 ± 0.203
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.198HisArg: 2.198 ± 0.696
2.198HisSer: 2.198 ± 0.541
1.57HisThr: 1.57 ± 0.341
1.256HisVal: 1.256 ± 0.334
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.256IleAla: 1.256 ± 0.44
1.884IleCys: 1.884 ± 0.833
2.513IleAsp: 2.513 ± 0.884
1.57IleGlu: 1.57 ± 0.531
1.57IlePhe: 1.57 ± 0.382
1.884IleGly: 1.884 ± 0.526
0.314IleHis: 0.314 ± 0.203
4.397IleIle: 4.397 ± 0.546
5.025IleLys: 5.025 ± 0.96
4.083IleLeu: 4.083 ± 0.305
0.628IleMet: 0.628 ± 0.167
4.711IleAsn: 4.711 ± 1.075
2.827IlePro: 2.827 ± 0.296
1.57IleGln: 1.57 ± 0.391
3.455IleArg: 3.455 ± 0.858
6.281IleSer: 6.281 ± 1.151
3.769IleThr: 3.769 ± 0.963
3.141IleVal: 3.141 ± 0.445
0.628IleTrp: 0.628 ± 0.481
1.256IleTyr: 1.256 ± 0.334
0.0IleXaa: 0.0 ± 0.0
Lys
1.884LysAla: 1.884 ± 0.526
0.628LysCys: 0.628 ± 0.167
6.281LysAsp: 6.281 ± 1.558
3.769LysGlu: 3.769 ± 1.003
2.827LysPhe: 2.827 ± 0.296
4.711LysGly: 4.711 ± 1.411
1.256LysHis: 1.256 ± 0.44
1.884LysIle: 1.884 ± 2.012
2.198LysLys: 2.198 ± 1.358
6.281LysLeu: 6.281 ± 1.315
1.884LysMet: 1.884 ± 0.502
4.083LysAsn: 4.083 ± 1.023
2.827LysPro: 2.827 ± 0.412
2.513LysGln: 2.513 ± 0.879
4.083LysArg: 4.083 ± 0.96
8.48LysSer: 8.48 ± 0.888
5.967LysThr: 5.967 ± 0.972
9.736LysVal: 9.736 ± 1.589
0.628LysTrp: 0.628 ± 0.167
3.769LysTyr: 3.769 ± 0.929
0.0LysXaa: 0.0 ± 0.0
Leu
4.397LeuAla: 4.397 ± 0.216
2.513LeuCys: 2.513 ± 0.46
6.595LeuAsp: 6.595 ± 1.169
6.91LeuGlu: 6.91 ± 1.224
4.711LeuPhe: 4.711 ± 1.316
1.884LeuGly: 1.884 ± 1.214
1.256LeuHis: 1.256 ± 0.334
3.769LeuIle: 3.769 ± 0.883
8.48LeuLys: 8.48 ± 0.946
7.538LeuLeu: 7.538 ± 0.568
2.827LeuMet: 2.827 ± 0.535
6.281LeuAsn: 6.281 ± 1.315
4.397LeuPro: 4.397 ± 0.463
3.769LeuGln: 3.769 ± 0.929
3.769LeuArg: 3.769 ± 1.042
10.678LeuSer: 10.678 ± 0.721
4.397LeuThr: 4.397 ± 1.1
6.281LeuVal: 6.281 ± 1.27
0.314LeuTrp: 0.314 ± 0.203
1.884LeuTyr: 1.884 ± 0.526
0.314LeuXaa: 0.314 ± 0.203
Met
2.198MetAla: 2.198 ± 0.736
0.628MetCys: 0.628 ± 0.167
1.57MetAsp: 1.57 ± 0.391
1.256MetGlu: 1.256 ± 0.344
0.0MetPhe: 0.0 ± 0.0
1.884MetGly: 1.884 ± 0.659
0.628MetHis: 0.628 ± 0.167
1.884MetIle: 1.884 ± 0.506
2.827MetLys: 2.827 ± 0.412
1.256MetLeu: 1.256 ± 0.334
0.628MetMet: 0.628 ± 0.167
2.198MetAsn: 2.198 ± 0.541
1.256MetPro: 1.256 ± 0.334
0.942MetGln: 0.942 ± 0.263
0.628MetArg: 0.628 ± 0.167
1.256MetSer: 1.256 ± 1.115
0.942MetThr: 0.942 ± 0.263
1.884MetVal: 1.884 ± 0.502
0.314MetTrp: 0.314 ± 0.203
0.942MetTyr: 0.942 ± 0.52
0.0MetXaa: 0.0 ± 0.0
Asn
2.198AsnAla: 2.198 ± 0.541
0.628AsnCys: 0.628 ± 0.481
2.513AsnAsp: 2.513 ± 0.245
2.513AsnGlu: 2.513 ± 0.503
4.397AsnPhe: 4.397 ± 1.082
3.455AsnGly: 3.455 ± 1.668
1.256AsnHis: 1.256 ± 0.334
0.628AsnIle: 0.628 ± 1.07
4.083AsnLys: 4.083 ± 0.533
6.281AsnLeu: 6.281 ± 0.932
0.0AsnMet: 0.0 ± 0.0
2.827AsnAsn: 2.827 ± 0.535
1.884AsnPro: 1.884 ± 1.039
1.256AsnGln: 1.256 ± 1.115
1.57AsnArg: 1.57 ± 0.48
3.455AsnSer: 3.455 ± 0.949
2.198AsnThr: 2.198 ± 0.541
2.827AsnVal: 2.827 ± 0.296
0.0AsnTrp: 0.0 ± 0.0
1.884AsnTyr: 1.884 ± 0.833
0.0AsnXaa: 0.0 ± 0.0
Pro
3.455ProAla: 3.455 ± 0.575
0.628ProCys: 0.628 ± 0.481
2.827ProAsp: 2.827 ± 0.296
2.198ProGlu: 2.198 ± 0.541
2.513ProPhe: 2.513 ± 0.669
2.198ProGly: 2.198 ± 0.541
0.628ProHis: 0.628 ± 0.167
2.513ProIle: 2.513 ± 0.557
5.967ProLys: 5.967 ± 1.47
6.281ProLeu: 6.281 ± 0.586
1.256ProMet: 1.256 ± 0.608
1.256ProAsn: 1.256 ± 0.784
0.0ProPro: 0.0 ± 0.0
0.628ProGln: 0.628 ± 0.574
1.256ProArg: 1.256 ± 0.44
2.198ProSer: 2.198 ± 1.101
2.198ProThr: 2.198 ± 1.218
1.57ProVal: 1.57 ± 0.48
0.0ProTrp: 0.0 ± 0.0
0.942ProTyr: 0.942 ± 0.416
0.0ProXaa: 0.0 ± 0.0
Gln
2.198GlnAla: 2.198 ± 0.497
0.0GlnCys: 0.0 ± 0.0
2.198GlnAsp: 2.198 ± 0.541
1.256GlnGlu: 1.256 ± 0.44
2.513GlnPhe: 2.513 ± 0.987
0.942GlnGly: 0.942 ± 0.263
0.628GlnHis: 0.628 ± 0.167
3.769GlnIle: 3.769 ± 0.929
0.942GlnLys: 0.942 ± 0.263
1.884GlnLeu: 1.884 ± 0.83
0.628GlnMet: 0.628 ± 0.167
1.256GlnAsn: 1.256 ± 0.484
0.628GlnPro: 0.628 ± 0.574
4.083GlnGln: 4.083 ± 1.4
0.942GlnArg: 0.942 ± 0.263
3.769GlnSer: 3.769 ± 0.475
2.827GlnThr: 2.827 ± 0.508
1.57GlnVal: 1.57 ± 0.695
0.0GlnTrp: 0.0 ± 0.0
0.314GlnTyr: 0.314 ± 0.203
0.0GlnXaa: 0.0 ± 0.0
Arg
3.455ArgAla: 3.455 ± 0.53
0.628ArgCys: 0.628 ± 0.167
2.827ArgAsp: 2.827 ± 0.412
1.884ArgGlu: 1.884 ± 0.248
2.827ArgPhe: 2.827 ± 0.972
4.083ArgGly: 4.083 ± 0.31
1.256ArgHis: 1.256 ± 0.334
1.57ArgIle: 1.57 ± 1.239
1.884ArgLys: 1.884 ± 0.83
4.083ArgLeu: 4.083 ± 1.078
0.942ArgMet: 0.942 ± 0.416
1.57ArgAsn: 1.57 ± 0.695
0.942ArgPro: 0.942 ± 0.263
1.256ArgGln: 1.256 ± 0.44
2.827ArgArg: 2.827 ± 0.565
4.711ArgSer: 4.711 ± 0.373
2.827ArgThr: 2.827 ± 0.508
4.397ArgVal: 4.397 ± 0.994
0.314ArgTrp: 0.314 ± 0.203
1.57ArgTyr: 1.57 ± 0.531
0.0ArgXaa: 0.0 ± 0.0
Ser
6.91SerAla: 6.91 ± 1.125
0.628SerCys: 0.628 ± 0.167
7.852SerAsp: 7.852 ± 1.43
5.025SerGlu: 5.025 ± 0.894
3.769SerPhe: 3.769 ± 0.712
5.339SerGly: 5.339 ± 0.992
0.628SerHis: 0.628 ± 0.167
5.339SerIle: 5.339 ± 1.295
6.91SerLys: 6.91 ± 0.356
4.083SerLeu: 4.083 ± 0.946
2.198SerMet: 2.198 ± 0.425
1.256SerAsn: 1.256 ± 0.334
2.513SerPro: 2.513 ± 0.646
1.57SerGln: 1.57 ± 0.391
2.198SerArg: 2.198 ± 1.101
4.083SerSer: 4.083 ± 0.946
4.083SerThr: 4.083 ± 0.668
8.794SerVal: 8.794 ± 1.076
0.0SerTrp: 0.0 ± 0.0
2.827SerTyr: 2.827 ± 0.972
0.0SerXaa: 0.0 ± 0.0
Thr
3.141ThrAla: 3.141 ± 0.764
1.57ThrCys: 1.57 ± 0.391
0.314ThrAsp: 0.314 ± 0.605
1.884ThrGlu: 1.884 ± 1.739
5.967ThrPhe: 5.967 ± 0.877
2.198ThrGly: 2.198 ± 0.55
0.628ThrHis: 0.628 ± 0.167
2.198ThrIle: 2.198 ± 0.79
2.827ThrLys: 2.827 ± 0.699
5.653ThrLeu: 5.653 ± 0.843
1.57ThrMet: 1.57 ± 0.695
2.198ThrAsn: 2.198 ± 0.497
4.083ThrPro: 4.083 ± 1.035
2.198ThrGln: 2.198 ± 0.497
3.769ThrArg: 3.769 ± 0.883
2.827ThrSer: 2.827 ± 1.072
2.198ThrThr: 2.198 ± 1.845
5.653ThrVal: 5.653 ± 0.98
0.942ThrTrp: 0.942 ± 0.52
4.711ThrTyr: 4.711 ± 1.188
0.0ThrXaa: 0.0 ± 0.0
Val
5.653ValAla: 5.653 ± 1.064
1.57ValCys: 1.57 ± 0.341
5.653ValAsp: 5.653 ± 1.486
3.455ValGlu: 3.455 ± 1.353
1.884ValPhe: 1.884 ± 0.502
2.198ValGly: 2.198 ± 0.736
2.827ValHis: 2.827 ± 0.699
5.653ValIle: 5.653 ± 1.398
5.025ValLys: 5.025 ± 0.49
7.852ValLeu: 7.852 ± 1.129
1.57ValMet: 1.57 ± 0.341
5.025ValAsn: 5.025 ± 0.49
4.397ValPro: 4.397 ± 0.457
0.942ValGln: 0.942 ± 0.52
3.769ValArg: 3.769 ± 0.478
6.91ValSer: 6.91 ± 0.627
5.025ValThr: 5.025 ± 0.817
6.595ValVal: 6.595 ± 2.286
1.256ValTrp: 1.256 ± 0.484
5.653ValTyr: 5.653 ± 0.435
0.0ValXaa: 0.0 ± 0.0
Trp
0.942TrpAla: 0.942 ± 0.52
0.0TrpCys: 0.0 ± 0.0
0.942TrpAsp: 0.942 ± 0.263
0.942TrpGlu: 0.942 ± 0.263
1.256TrpPhe: 1.256 ± 0.334
0.628TrpGly: 0.628 ± 0.167
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.942TrpLys: 0.942 ± 0.263
0.628TrpLeu: 0.628 ± 0.167
0.314TrpMet: 0.314 ± 0.203
0.628TrpAsn: 0.628 ± 0.481
0.0TrpPro: 0.0 ± 0.0
0.628TrpGln: 0.628 ± 0.923
0.628TrpArg: 0.628 ± 0.167
0.628TrpSer: 0.628 ± 0.167
0.314TrpThr: 0.314 ± 0.605
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.314TrpTyr: 0.314 ± 0.203
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.57TyrAla: 1.57 ± 0.391
0.0TyrCys: 0.0 ± 0.0
4.711TyrAsp: 4.711 ± 0.895
1.884TyrGlu: 1.884 ± 0.833
1.57TyrPhe: 1.57 ± 0.531
1.57TyrGly: 1.57 ± 0.391
1.884TyrHis: 1.884 ± 0.248
1.884TyrIle: 1.884 ± 0.83
4.083TyrLys: 4.083 ± 1.023
3.141TyrLeu: 3.141 ± 0.358
1.57TyrMet: 1.57 ± 0.276
2.198TyrAsn: 2.198 ± 0.497
1.256TyrPro: 1.256 ± 0.334
1.57TyrGln: 1.57 ± 0.391
0.628TyrArg: 0.628 ± 0.574
2.198TyrSer: 2.198 ± 0.339
4.083TyrThr: 4.083 ± 0.677
1.57TyrVal: 1.57 ± 0.341
0.0TyrTrp: 0.0 ± 0.0
1.884TyrTyr: 1.884 ± 0.526
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.314XaaGln: 0.314 ± 0.203
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski