Amino acid dipepetide frequency for Ochrobactrum gallinifaecis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.848AlaAla: 12.848 ± 0.153	0.863AlaCys: 0.863 ± 0.033	6.034AlaAsp: 6.034 ± 0.079	6.505AlaGlu: 6.505 ± 0.088	4.261AlaPhe: 4.261 ± 0.068	8.948AlaGly: 8.948 ± 0.122	2.115AlaHis: 2.115 ± 0.047	7.22AlaIle: 7.22 ± 0.089	4.614AlaLys: 4.614 ± 0.074	11.773AlaLeu: 11.773 ± 0.117	3.13AlaMet: 3.13 ± 0.059	3.232AlaAsn: 3.232 ± 0.059	4.347AlaPro: 4.347 ± 0.075	3.968AlaGln: 3.968 ± 0.064	6.514AlaArg: 6.514 ± 0.089	6.457AlaSer: 6.457 ± 0.097	5.202AlaThr: 5.202 ± 0.071	7.423AlaVal: 7.423 ± 0.099	1.162AlaTrp: 1.162 ± 0.036	2.647AlaTyr: 2.647 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.792CysAla: 0.792 ± 0.026	0.106CysCys: 0.106 ± 0.012	0.511CysAsp: 0.511 ± 0.025	0.403CysGlu: 0.403 ± 0.018	0.382CysPhe: 0.382 ± 0.022	0.815CysGly: 0.815 ± 0.029	0.209CysHis: 0.209 ± 0.014	0.446CysIle: 0.446 ± 0.021	0.261CysLys: 0.261 ± 0.016	0.737CysLeu: 0.737 ± 0.026	0.16CysMet: 0.16 ± 0.013	0.243CysAsn: 0.243 ± 0.017	0.351CysPro: 0.351 ± 0.019	0.243CysGln: 0.243 ± 0.016	0.441CysArg: 0.441 ± 0.025	0.461CysSer: 0.461 ± 0.021	0.378CysThr: 0.378 ± 0.019	0.513CysVal: 0.513 ± 0.023	0.103CysTrp: 0.103 ± 0.01	0.188CysTyr: 0.188 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.038AspAla: 6.038 ± 0.084	0.496AspCys: 0.496 ± 0.024	3.102AspAsp: 3.102 ± 0.065	3.737AspGlu: 3.737 ± 0.062	2.337AspPhe: 2.337 ± 0.054	4.576AspGly: 4.576 ± 0.083	1.293AspHis: 1.293 ± 0.037	3.784AspIle: 3.784 ± 0.066	2.425AspLys: 2.425 ± 0.044	5.306AspLeu: 5.306 ± 0.094	1.494AspMet: 1.494 ± 0.038	1.903AspAsn: 1.903 ± 0.05	2.863AspPro: 2.863 ± 0.049	1.834AspGln: 1.834 ± 0.044	3.67AspArg: 3.67 ± 0.067	2.371AspSer: 2.371 ± 0.055	2.578AspThr: 2.578 ± 0.057	3.999AspVal: 3.999 ± 0.065	0.86AspTrp: 0.86 ± 0.031	1.662AspTyr: 1.662 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	6.75GluAla: 6.75 ± 0.093	0.344GluCys: 0.344 ± 0.019	2.865GluAsp: 2.865 ± 0.058	3.553GluGlu: 3.553 ± 0.07	1.9GluPhe: 1.9 ± 0.046	4.028GluGly: 4.028 ± 0.065	1.238GluHis: 1.238 ± 0.036	3.974GluIle: 3.974 ± 0.065	3.375GluLys: 3.375 ± 0.058	5.52GluLeu: 5.52 ± 0.081	1.58GluMet: 1.58 ± 0.041	2.428GluAsn: 2.428 ± 0.047	2.431GluPro: 2.431 ± 0.058	2.37GluGln: 2.37 ± 0.048	4.511GluArg: 4.511 ± 0.078	2.478GluSer: 2.478 ± 0.043	3.617GluThr: 3.617 ± 0.062	3.581GluVal: 3.581 ± 0.063	0.724GluTrp: 0.724 ± 0.027	1.219GluTyr: 1.219 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.351PheAla: 4.351 ± 0.067	0.371PheCys: 0.371 ± 0.02	2.707PheAsp: 2.707 ± 0.053	2.266PheGlu: 2.266 ± 0.053	1.66PhePhe: 1.66 ± 0.053	3.625PheGly: 3.625 ± 0.066	0.787PheHis: 0.787 ± 0.027	2.393PheIle: 2.393 ± 0.059	1.407PheLys: 1.407 ± 0.041	3.578PheLeu: 3.578 ± 0.072	0.952PheMet: 0.952 ± 0.028	1.437PheAsn: 1.437 ± 0.037	1.537PhePro: 1.537 ± 0.038	1.109PheGln: 1.109 ± 0.034	2.145PheArg: 2.145 ± 0.046	2.736PheSer: 2.736 ± 0.053	2.084PheThr: 2.084 ± 0.05	2.871PheVal: 2.871 ± 0.066	0.598PheTrp: 0.598 ± 0.025	1.052PheTyr: 1.052 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	7.868GlyAla: 7.868 ± 0.125	0.699GlyCys: 0.699 ± 0.025	4.146GlyAsp: 4.146 ± 0.089	4.522GlyGlu: 4.522 ± 0.074	3.713GlyPhe: 3.713 ± 0.07	6.8GlyGly: 6.8 ± 0.334	1.703GlyHis: 1.703 ± 0.045	5.375GlyIle: 5.375 ± 0.083	4.166GlyLys: 4.166 ± 0.076	8.1GlyLeu: 8.1 ± 0.091	2.148GlyMet: 2.148 ± 0.045	2.776GlyAsn: 2.776 ± 0.085	2.706GlyPro: 2.706 ± 0.045	2.801GlyGln: 2.801 ± 0.053	4.937GlyArg: 4.937 ± 0.081	4.949GlySer: 4.949 ± 0.121	4.486GlyThr: 4.486 ± 0.121	5.743GlyVal: 5.743 ± 0.08	1.163GlyTrp: 1.163 ± 0.036	2.326GlyTyr: 2.326 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.018HisAla: 2.018 ± 0.052	0.201HisCys: 0.201 ± 0.014	1.24HisAsp: 1.24 ± 0.036	1.185HisGlu: 1.185 ± 0.039	0.889HisPhe: 0.889 ± 0.031	1.734HisGly: 1.734 ± 0.041	0.55HisHis: 0.55 ± 0.029	1.307HisIle: 1.307 ± 0.036	0.744HisLys: 0.744 ± 0.03	1.952HisLeu: 1.952 ± 0.041	0.566HisMet: 0.566 ± 0.02	0.627HisAsn: 0.627 ± 0.026	1.136HisPro: 1.136 ± 0.038	0.638HisGln: 0.638 ± 0.025	1.221HisArg: 1.221 ± 0.035	1.09HisSer: 1.09 ± 0.036	0.838HisThr: 0.838 ± 0.029	1.385HisVal: 1.385 ± 0.045	0.29HisTrp: 0.29 ± 0.015	0.631HisTyr: 0.631 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	8.101IleAla: 8.101 ± 0.107	0.607IleCys: 0.607 ± 0.022	4.206IleAsp: 4.206 ± 0.065	4.21IleGlu: 4.21 ± 0.068	2.287IlePhe: 2.287 ± 0.051	5.714IleGly: 5.714 ± 0.091	1.11IleHis: 1.11 ± 0.033	3.929IleIle: 3.929 ± 0.063	2.276IleLys: 2.276 ± 0.054	5.51IleLeu: 5.51 ± 0.071	1.366IleMet: 1.366 ± 0.032	2.229IleAsn: 2.229 ± 0.05	2.651IlePro: 2.651 ± 0.047	1.545IleGln: 1.545 ± 0.037	3.564IleArg: 3.564 ± 0.067	4.078IleSer: 4.078 ± 0.07	3.322IleThr: 3.322 ± 0.055	4.876IleVal: 4.876 ± 0.072	0.694IleTrp: 0.694 ± 0.029	1.508IleTyr: 1.508 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	5.057LysAla: 5.057 ± 0.081	0.172LysCys: 0.172 ± 0.012	2.302LysAsp: 2.302 ± 0.058	2.242LysGlu: 2.242 ± 0.047	1.216LysPhe: 1.216 ± 0.039	3.249LysGly: 3.249 ± 0.065	0.852LysHis: 0.852 ± 0.029	2.735LysIle: 2.735 ± 0.052	2.108LysLys: 2.108 ± 0.052	4.4LysLeu: 4.4 ± 0.069	1.098LysMet: 1.098 ± 0.035	1.612LysAsn: 1.612 ± 0.039	2.544LysPro: 2.544 ± 0.049	1.512LysGln: 1.512 ± 0.039	2.963LysArg: 2.963 ± 0.05	2.635LysSer: 2.635 ± 0.049	2.576LysThr: 2.576 ± 0.052	2.781LysVal: 2.781 ± 0.054	0.463LysTrp: 0.463 ± 0.021	0.813LysTyr: 0.813 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	11.243LeuAla: 11.243 ± 0.122	0.856LeuCys: 0.856 ± 0.029	5.653LeuAsp: 5.653 ± 0.074	5.374LeuGlu: 5.374 ± 0.081	3.765LeuPhe: 3.765 ± 0.061	7.714LeuGly: 7.714 ± 0.094	1.851LeuHis: 1.851 ± 0.041	6.071LeuIle: 6.071 ± 0.099	4.489LeuLys: 4.489 ± 0.071	8.952LeuLeu: 8.952 ± 0.119	2.437LeuMet: 2.437 ± 0.045	3.296LeuAsn: 3.296 ± 0.063	5.084LeuPro: 5.084 ± 0.081	2.88LeuGln: 2.88 ± 0.045	5.845LeuArg: 5.845 ± 0.075	7.103LeuSer: 7.103 ± 0.087	5.33LeuThr: 5.33 ± 0.083	6.896LeuVal: 6.896 ± 0.074	1.001LeuTrp: 1.001 ± 0.032	2.268LeuTyr: 2.268 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	2.748MetAla: 2.748 ± 0.058	0.156MetCys: 0.156 ± 0.011	1.134MetAsp: 1.134 ± 0.033	1.239MetGlu: 1.239 ± 0.033	0.745MetPhe: 0.745 ± 0.025	1.788MetGly: 1.788 ± 0.05	0.5MetHis: 0.5 ± 0.023	1.618MetIle: 1.618 ± 0.039	1.247MetLys: 1.247 ± 0.035	2.628MetLeu: 2.628 ± 0.055	0.733MetMet: 0.733 ± 0.028	1.024MetAsn: 1.024 ± 0.033	1.419MetPro: 1.419 ± 0.039	1.015MetGln: 1.015 ± 0.029	1.823MetArg: 1.823 ± 0.037	1.833MetSer: 1.833 ± 0.04	1.767MetThr: 1.767 ± 0.04	1.68MetVal: 1.68 ± 0.038	0.22MetTrp: 0.22 ± 0.016	0.286MetTyr: 0.286 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	3.801AsnAla: 3.801 ± 0.075	0.257AsnCys: 0.257 ± 0.015	1.878AsnAsp: 1.878 ± 0.043	1.814AsnGlu: 1.814 ± 0.04	1.291AsnPhe: 1.291 ± 0.036	3.134AsnGly: 3.134 ± 0.081	0.663AsnHis: 0.663 ± 0.028	2.248AsnIle: 2.248 ± 0.046	1.242AsnLys: 1.242 ± 0.039	3.073AsnLeu: 3.073 ± 0.059	0.865AsnMet: 0.865 ± 0.028	1.181AsnAsn: 1.181 ± 0.04	2.059AsnPro: 2.059 ± 0.05	1.008AsnGln: 1.008 ± 0.034	2.168AsnArg: 2.168 ± 0.043	1.894AsnSer: 1.894 ± 0.05	1.588AsnThr: 1.588 ± 0.053	2.436AsnVal: 2.436 ± 0.052	0.538AsnTrp: 0.538 ± 0.022	0.933AsnTyr: 0.933 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	4.804ProAla: 4.804 ± 0.083	0.286ProCys: 0.286 ± 0.018	3.204ProAsp: 3.204 ± 0.055	3.48ProGlu: 3.48 ± 0.071	1.977ProPhe: 1.977 ± 0.042	3.556ProGly: 3.556 ± 0.06	0.996ProHis: 0.996 ± 0.032	2.385ProIle: 2.385 ± 0.044	1.906ProLys: 1.906 ± 0.054	4.271ProLeu: 4.271 ± 0.075	1.015ProMet: 1.015 ± 0.03	1.424ProAsn: 1.424 ± 0.039	1.675ProPro: 1.675 ± 0.052	1.796ProGln: 1.796 ± 0.039	2.228ProArg: 2.228 ± 0.056	2.721ProSer: 2.721 ± 0.057	2.136ProThr: 2.136 ± 0.043	4.056ProVal: 4.056 ± 0.068	0.596ProTrp: 0.596 ± 0.023	1.221ProTyr: 1.221 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	3.871GlnAla: 3.871 ± 0.064	0.21GlnCys: 0.21 ± 0.015	1.575GlnAsp: 1.575 ± 0.038	1.67GlnGlu: 1.67 ± 0.038	1.25GlnPhe: 1.25 ± 0.029	2.315GlnGly: 2.315 ± 0.052	0.704GlnHis: 0.704 ± 0.025	2.155GlnIle: 2.155 ± 0.052	1.623GlnLys: 1.623 ± 0.038	3.171GlnLeu: 3.171 ± 0.06	0.932GlnMet: 0.932 ± 0.031	1.253GlnAsn: 1.253 ± 0.035	1.67GlnPro: 1.67 ± 0.043	1.477GlnGln: 1.477 ± 0.047	2.34GlnArg: 2.34 ± 0.052	2.292GlnSer: 2.292 ± 0.062	1.866GlnThr: 1.866 ± 0.047	2.184GlnVal: 2.184 ± 0.047	0.43GlnTrp: 0.43 ± 0.02	0.754GlnTyr: 0.754 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	5.733ArgAla: 5.733 ± 0.08	0.383ArgCys: 0.383 ± 0.02	3.518ArgAsp: 3.518 ± 0.062	3.891ArgGlu: 3.891 ± 0.071	2.809ArgPhe: 2.809 ± 0.057	4.027ArgGly: 4.027 ± 0.058	1.414ArgHis: 1.414 ± 0.034	4.332ArgIle: 4.332 ± 0.062	2.857ArgLys: 2.857 ± 0.056	6.661ArgLeu: 6.661 ± 0.096	1.693ArgMet: 1.693 ± 0.04	2.278ArgAsn: 2.278 ± 0.046	2.728ArgPro: 2.728 ± 0.059	2.345ArgGln: 2.345 ± 0.048	4.223ArgArg: 4.223 ± 0.071	3.646ArgSer: 3.646 ± 0.063	2.874ArgThr: 2.874 ± 0.054	4.064ArgVal: 4.064 ± 0.062	0.763ArgTrp: 0.763 ± 0.028	1.707ArgTyr: 1.707 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.27SerAla: 6.27 ± 0.102	0.416SerCys: 0.416 ± 0.022	3.461SerAsp: 3.461 ± 0.054	3.399SerGlu: 3.399 ± 0.057	2.771SerPhe: 2.771 ± 0.057	5.992SerGly: 5.992 ± 0.115	1.204SerHis: 1.204 ± 0.033	3.683SerIle: 3.683 ± 0.061	2.347SerLys: 2.347 ± 0.046	5.879SerLeu: 5.879 ± 0.075	1.543SerMet: 1.543 ± 0.035	1.95SerAsn: 1.95 ± 0.046	2.657SerPro: 2.657 ± 0.052	1.904SerGln: 1.904 ± 0.047	3.597SerArg: 3.597 ± 0.066	3.732SerSer: 3.732 ± 0.079	2.955SerThr: 2.955 ± 0.067	4.546SerVal: 4.546 ± 0.077	0.755SerTrp: 0.755 ± 0.024	1.544SerTyr: 1.544 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.598ThrAla: 5.598 ± 0.068	0.391ThrCys: 0.391 ± 0.019	2.804ThrAsp: 2.804 ± 0.057	2.667ThrGlu: 2.667 ± 0.05	2.014ThrPhe: 2.014 ± 0.047	5.05ThrGly: 5.05 ± 0.104	0.976ThrHis: 0.976 ± 0.034	3.565ThrIle: 3.565 ± 0.056	1.873ThrLys: 1.873 ± 0.043	5.605ThrLeu: 5.605 ± 0.111	1.215ThrMet: 1.215 ± 0.033	1.581ThrAsn: 1.581 ± 0.046	2.962ThrPro: 2.962 ± 0.06	1.627ThrGln: 1.627 ± 0.039	2.95ThrArg: 2.95 ± 0.051	3.08ThrSer: 3.08 ± 0.055	2.85ThrThr: 2.85 ± 0.059	3.997ThrVal: 3.997 ± 0.069	0.545ThrTrp: 0.545 ± 0.026	1.297ThrTyr: 1.297 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	7.811ValAla: 7.811 ± 0.101	0.578ValCys: 0.578 ± 0.023	3.872ValAsp: 3.872 ± 0.066	4.443ValGlu: 4.443 ± 0.071	2.836ValPhe: 2.836 ± 0.062	5.067ValGly: 5.067 ± 0.094	1.28ValHis: 1.28 ± 0.04	4.634ValIle: 4.634 ± 0.075	2.903ValLys: 2.903 ± 0.054	7.054ValLeu: 7.054 ± 0.089	1.814ValMet: 1.814 ± 0.049	2.216ValAsn: 2.216 ± 0.045	3.232ValPro: 3.232 ± 0.061	2.163ValGln: 2.163 ± 0.041	4.156ValArg: 4.156 ± 0.067	4.772ValSer: 4.772 ± 0.081	4.284ValThr: 4.284 ± 0.062	5.254ValVal: 5.254 ± 0.076	0.81ValTrp: 0.81 ± 0.027	1.537ValTyr: 1.537 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.068TrpAla: 1.068 ± 0.038	0.112TrpCys: 0.112 ± 0.01	0.588TrpAsp: 0.588 ± 0.024	0.515TrpGlu: 0.515 ± 0.023	0.512TrpPhe: 0.512 ± 0.02	0.802TrpGly: 0.802 ± 0.029	0.3TrpHis: 0.3 ± 0.017	0.673TrpIle: 0.673 ± 0.023	0.569TrpLys: 0.569 ± 0.02	1.521TrpLeu: 1.521 ± 0.044	0.308TrpMet: 0.308 ± 0.016	0.538TrpAsn: 0.538 ± 0.023	0.59TrpPro: 0.59 ± 0.022	0.582TrpGln: 0.582 ± 0.023	0.91TrpArg: 0.91 ± 0.033	0.789TrpSer: 0.789 ± 0.029	0.65TrpThr: 0.65 ± 0.024	0.741TrpVal: 0.741 ± 0.026	0.201TrpTrp: 0.201 ± 0.013	0.3TrpTyr: 0.3 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.492TyrAla: 2.492 ± 0.046	0.239TyrCys: 0.239 ± 0.015	1.53TyrAsp: 1.53 ± 0.044	1.373TyrGlu: 1.373 ± 0.034	1.052TyrPhe: 1.052 ± 0.029	2.195TyrGly: 2.195 ± 0.053	0.496TyrHis: 0.496 ± 0.021	1.256TyrIle: 1.256 ± 0.036	0.898TyrLys: 0.898 ± 0.031	2.417TyrLeu: 2.417 ± 0.053	0.551TyrMet: 0.551 ± 0.022	0.844TyrAsn: 0.844 ± 0.03	1.093TyrPro: 1.093 ± 0.033	0.925TyrGln: 0.925 ± 0.033	1.739TyrArg: 1.739 ± 0.039	1.488TyrSer: 1.488 ± 0.044	1.265TyrThr: 1.265 ± 0.04	1.688TyrVal: 1.688 ± 0.046	0.353TyrTrp: 0.353 ± 0.017	0.701TyrTyr: 0.701 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3370 proteins (1063554 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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