Amino acid dipepetide frequency for Leptonychotes weddellii papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.994AlaAla: 8.994 ± 1.659
0.428AlaCys: 0.428 ± 0.353
4.711AlaAsp: 4.711 ± 1.65
5.567AlaGlu: 5.567 ± 1.849
3.426AlaPhe: 3.426 ± 1.017
5.139AlaGly: 5.139 ± 1.739
1.285AlaHis: 1.285 ± 0.436
2.57AlaIle: 2.57 ± 0.836
4.283AlaLys: 4.283 ± 1.55
4.283AlaLeu: 4.283 ± 2.091
2.141AlaMet: 2.141 ± 1.326
0.857AlaAsn: 0.857 ± 0.676
5.567AlaPro: 5.567 ± 1.396
4.711AlaGln: 4.711 ± 0.796
6.852AlaArg: 6.852 ± 2.377
2.57AlaSer: 2.57 ± 1.066
5.567AlaThr: 5.567 ± 1.15
2.57AlaVal: 2.57 ± 0.885
1.285AlaTrp: 1.285 ± 0.813
1.713AlaTyr: 1.713 ± 0.625
0.0AlaXaa: 0.0 ± 0.0
Cys
2.57CysAla: 2.57 ± 2.232
0.428CysCys: 0.428 ± 0.656
1.285CysAsp: 1.285 ± 0.426
1.285CysGlu: 1.285 ± 1.014
1.285CysPhe: 1.285 ± 0.813
2.141CysGly: 2.141 ± 1.554
0.0CysHis: 0.0 ± 0.0
0.428CysIle: 0.428 ± 0.338
2.57CysLys: 2.57 ± 1.334
1.285CysLeu: 1.285 ± 0.661
0.0CysMet: 0.0 ± 0.0
1.713CysAsn: 1.713 ± 0.947
2.57CysPro: 2.57 ± 1.198
0.857CysGln: 0.857 ± 0.407
1.285CysArg: 1.285 ± 0.722
2.57CysSer: 2.57 ± 1.359
0.428CysThr: 0.428 ± 0.656
0.857CysVal: 0.857 ± 0.703
1.285CysTrp: 1.285 ± 0.426
0.857CysTyr: 0.857 ± 0.732
0.0CysXaa: 0.0 ± 0.0
Asp
5.139AspAla: 5.139 ± 0.835
2.57AspCys: 2.57 ± 0.746
2.998AspAsp: 2.998 ± 0.586
2.141AspGlu: 2.141 ± 0.969
1.285AspPhe: 1.285 ± 0.757
5.139AspGly: 5.139 ± 1.478
0.857AspHis: 0.857 ± 0.676
3.854AspIle: 3.854 ± 1.339
1.713AspLys: 1.713 ± 0.573
4.711AspLeu: 4.711 ± 0.957
0.857AspMet: 0.857 ± 0.436
2.141AspAsn: 2.141 ± 0.893
1.713AspPro: 1.713 ± 0.608
2.141AspGln: 2.141 ± 1.055
2.141AspArg: 2.141 ± 0.531
4.283AspSer: 4.283 ± 0.997
4.283AspThr: 4.283 ± 1.561
3.426AspVal: 3.426 ± 1.437
0.857AspTrp: 0.857 ± 0.676
2.141AspTyr: 2.141 ± 0.735
0.0AspXaa: 0.0 ± 0.0
Glu
3.854GluAla: 3.854 ± 0.494
0.857GluCys: 0.857 ± 0.676
5.567GluAsp: 5.567 ± 2.864
4.711GluGlu: 4.711 ± 2.095
1.713GluPhe: 1.713 ± 1.253
7.281GluGly: 7.281 ± 1.817
1.285GluHis: 1.285 ± 0.37
2.141GluIle: 2.141 ± 0.848
1.285GluLys: 1.285 ± 0.898
5.567GluLeu: 5.567 ± 1.871
1.285GluMet: 1.285 ± 0.426
3.854GluAsn: 3.854 ± 1.61
2.998GluPro: 2.998 ± 1.39
2.57GluGln: 2.57 ± 0.671
2.998GluArg: 2.998 ± 2.109
3.854GluSer: 3.854 ± 0.756
3.426GluThr: 3.426 ± 1.469
6.424GluVal: 6.424 ± 1.652
0.428GluTrp: 0.428 ± 0.656
2.998GluTyr: 2.998 ± 1.064
0.0GluXaa: 0.0 ± 0.0
Phe
2.998PheAla: 2.998 ± 1.064
2.141PheCys: 2.141 ± 1.577
2.57PheAsp: 2.57 ± 1.375
3.426PheGlu: 3.426 ± 0.905
2.57PhePhe: 2.57 ± 0.759
3.426PheGly: 3.426 ± 1.33
0.428PheHis: 0.428 ± 0.353
0.857PheIle: 0.857 ± 0.436
2.57PheLys: 2.57 ± 1.295
3.426PheLeu: 3.426 ± 1.017
0.428PheMet: 0.428 ± 0.387
1.285PheAsn: 1.285 ± 0.37
0.857PhePro: 0.857 ± 0.412
2.141PheGln: 2.141 ± 0.641
2.998PheArg: 2.998 ± 0.905
1.713PheSer: 1.713 ± 0.665
0.857PheThr: 0.857 ± 0.436
0.857PheVal: 0.857 ± 0.412
0.857PheTrp: 0.857 ± 0.436
1.713PheTyr: 1.713 ± 0.994
0.0PheXaa: 0.0 ± 0.0
Gly
4.711GlyAla: 4.711 ± 1.296
2.998GlyCys: 2.998 ± 1.024
3.854GlyAsp: 3.854 ± 0.924
6.424GlyGlu: 6.424 ± 0.904
1.713GlyPhe: 1.713 ± 0.988
8.137GlyGly: 8.137 ± 2.488
2.57GlyHis: 2.57 ± 0.933
4.711GlyIle: 4.711 ± 1.233
0.857GlyLys: 0.857 ± 0.442
5.139GlyLeu: 5.139 ± 1.328
0.428GlyMet: 0.428 ± 0.56
3.854GlyAsn: 3.854 ± 1.162
5.139GlyPro: 5.139 ± 1.455
2.141GlyGln: 2.141 ± 0.459
7.709GlyArg: 7.709 ± 2.64
6.852GlySer: 6.852 ± 1.939
5.567GlyThr: 5.567 ± 1.405
1.713GlyVal: 1.713 ± 0.75
1.713GlyTrp: 1.713 ± 1.004
0.857GlyTyr: 0.857 ± 0.847
0.0GlyXaa: 0.0 ± 0.0
His
2.141HisAla: 2.141 ± 0.791
0.857HisCys: 0.857 ± 0.657
1.285HisAsp: 1.285 ± 0.37
0.0HisGlu: 0.0 ± 0.0
2.141HisPhe: 2.141 ± 1.052
1.285HisGly: 1.285 ± 0.976
0.857HisHis: 0.857 ± 0.623
0.428HisIle: 0.428 ± 0.353
0.428HisLys: 0.428 ± 0.353
1.713HisLeu: 1.713 ± 0.732
0.0HisMet: 0.0 ± 0.0
0.428HisAsn: 0.428 ± 0.338
1.713HisPro: 1.713 ± 0.573
0.857HisGln: 0.857 ± 0.676
1.713HisArg: 1.713 ± 0.815
0.857HisSer: 0.857 ± 0.442
1.713HisThr: 1.713 ± 0.705
1.713HisVal: 1.713 ± 1.253
1.285HisTrp: 1.285 ± 0.759
0.857HisTyr: 0.857 ± 0.436
0.0HisXaa: 0.0 ± 0.0
Ile
2.57IleAla: 2.57 ± 1.295
1.713IleCys: 1.713 ± 0.872
1.713IleAsp: 1.713 ± 0.665
2.57IleGlu: 2.57 ± 0.582
1.285IlePhe: 1.285 ± 0.37
3.854IleGly: 3.854 ± 1.86
1.285IleHis: 1.285 ± 0.37
0.857IleIle: 0.857 ± 0.51
1.285IleLys: 1.285 ± 0.426
2.57IleLeu: 2.57 ± 0.873
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
1.285IlePro: 1.285 ± 1.008
0.428IleGln: 0.428 ± 0.353
2.998IleArg: 2.998 ± 1.136
3.426IleSer: 3.426 ± 1.322
2.57IleThr: 2.57 ± 0.93
5.567IleVal: 5.567 ± 1.441
0.428IleTrp: 0.428 ± 0.378
1.285IleTyr: 1.285 ± 0.43
0.0IleXaa: 0.0 ± 0.0
Lys
1.713LysAla: 1.713 ± 0.843
2.141LysCys: 2.141 ± 0.694
1.713LysAsp: 1.713 ± 0.942
1.285LysGlu: 1.285 ± 0.718
2.141LysPhe: 2.141 ± 0.676
0.857LysGly: 0.857 ± 0.442
1.713LysHis: 1.713 ± 0.815
1.285LysIle: 1.285 ± 0.64
2.998LysLys: 2.998 ± 1.395
2.57LysLeu: 2.57 ± 0.75
0.428LysMet: 0.428 ± 0.353
4.283LysAsn: 4.283 ± 1.392
0.857LysPro: 0.857 ± 0.436
1.285LysGln: 1.285 ± 0.37
5.139LysArg: 5.139 ± 1.005
2.998LysSer: 2.998 ± 1.263
1.713LysThr: 1.713 ± 0.679
2.141LysVal: 2.141 ± 1.134
0.0LysTrp: 0.0 ± 0.0
2.141LysTyr: 2.141 ± 0.772
0.0LysXaa: 0.0 ± 0.0
Leu
4.283LeuAla: 4.283 ± 1.267
0.857LeuCys: 0.857 ± 0.436
5.567LeuAsp: 5.567 ± 1.32
6.424LeuGlu: 6.424 ± 1.023
4.711LeuPhe: 4.711 ± 1.387
7.281LeuGly: 7.281 ± 0.374
1.713LeuHis: 1.713 ± 0.532
0.857LeuIle: 0.857 ± 0.436
3.426LeuLys: 3.426 ± 1.497
8.137LeuLeu: 8.137 ± 2.601
1.713LeuMet: 1.713 ± 0.775
3.426LeuAsn: 3.426 ± 1.28
4.283LeuPro: 4.283 ± 1.35
5.996LeuGln: 5.996 ± 1.0
5.996LeuArg: 5.996 ± 0.778
8.565LeuSer: 8.565 ± 2.056
4.711LeuThr: 4.711 ± 2.197
5.139LeuVal: 5.139 ± 2.009
1.713LeuTrp: 1.713 ± 0.732
2.141LeuTyr: 2.141 ± 0.723
0.0LeuXaa: 0.0 ± 0.0
Met
1.713MetAla: 1.713 ± 0.572
0.857MetCys: 0.857 ± 0.436
0.857MetAsp: 0.857 ± 0.436
0.428MetGlu: 0.428 ± 0.338
0.0MetPhe: 0.0 ± 0.0
0.428MetGly: 0.428 ± 0.656
0.0MetHis: 0.0 ± 0.0
0.857MetIle: 0.857 ± 0.623
1.285MetLys: 1.285 ± 0.696
2.57MetLeu: 2.57 ± 1.595
0.0MetMet: 0.0 ± 0.0
0.428MetAsn: 0.428 ± 0.353
0.857MetPro: 0.857 ± 0.51
0.0MetGln: 0.0 ± 0.0
0.857MetArg: 0.857 ± 0.676
2.57MetSer: 2.57 ± 1.392
0.0MetThr: 0.0 ± 0.0
1.713MetVal: 1.713 ± 0.815
0.0MetTrp: 0.0 ± 0.0
0.428MetTyr: 0.428 ± 0.353
0.0MetXaa: 0.0 ± 0.0
Asn
3.426AsnAla: 3.426 ± 1.185
0.857AsnCys: 0.857 ± 0.676
0.428AsnAsp: 0.428 ± 0.338
3.854AsnGlu: 3.854 ± 2.212
2.141AsnPhe: 2.141 ± 0.656
1.713AsnGly: 1.713 ± 1.041
0.857AsnHis: 0.857 ± 0.412
1.285AsnIle: 1.285 ± 0.663
1.285AsnLys: 1.285 ± 0.37
3.426AsnLeu: 3.426 ± 1.788
0.0AsnMet: 0.0 ± 0.0
1.285AsnAsn: 1.285 ± 0.718
4.711AsnPro: 4.711 ± 1.192
1.713AsnGln: 1.713 ± 1.412
2.141AsnArg: 2.141 ± 0.98
2.141AsnSer: 2.141 ± 0.556
2.141AsnThr: 2.141 ± 1.111
2.141AsnVal: 2.141 ± 0.413
0.428AsnTrp: 0.428 ± 0.338
0.857AsnTyr: 0.857 ± 0.412
0.0AsnXaa: 0.0 ± 0.0
Pro
7.709ProAla: 7.709 ± 3.114
1.285ProCys: 1.285 ± 0.668
4.711ProAsp: 4.711 ± 1.023
4.283ProGlu: 4.283 ± 1.799
0.0ProPhe: 0.0 ± 0.0
3.854ProGly: 3.854 ± 1.573
0.0ProHis: 0.0 ± 0.0
0.857ProIle: 0.857 ± 0.676
2.141ProLys: 2.141 ± 1.111
5.567ProLeu: 5.567 ± 0.531
1.713ProMet: 1.713 ± 0.581
2.57ProAsn: 2.57 ± 0.502
8.994ProPro: 8.994 ± 1.244
1.713ProGln: 1.713 ± 0.679
4.283ProArg: 4.283 ± 2.628
5.996ProSer: 5.996 ± 2.755
4.711ProThr: 4.711 ± 0.976
4.711ProVal: 4.711 ± 1.541
1.285ProTrp: 1.285 ± 0.759
1.713ProTyr: 1.713 ± 1.049
0.0ProXaa: 0.0 ± 0.0
Gln
1.713GlnAla: 1.713 ± 0.648
1.285GlnCys: 1.285 ± 0.813
1.713GlnAsp: 1.713 ± 0.608
2.998GlnGlu: 2.998 ± 0.53
0.428GlnPhe: 0.428 ± 0.353
3.426GlnGly: 3.426 ± 0.628
0.857GlnHis: 0.857 ± 0.623
1.713GlnIle: 1.713 ± 0.824
1.713GlnLys: 1.713 ± 0.577
4.283GlnLeu: 4.283 ± 0.954
0.857GlnMet: 0.857 ± 0.436
0.857GlnAsn: 0.857 ± 0.436
3.854GlnPro: 3.854 ± 0.774
1.713GlnGln: 1.713 ± 0.947
2.57GlnArg: 2.57 ± 0.759
2.57GlnSer: 2.57 ± 0.754
2.141GlnThr: 2.141 ± 1.326
3.426GlnVal: 3.426 ± 0.925
0.428GlnTrp: 0.428 ± 0.338
1.285GlnTyr: 1.285 ± 0.688
0.0GlnXaa: 0.0 ± 0.0
Arg
8.565ArgAla: 8.565 ± 1.875
2.141ArgCys: 2.141 ± 1.41
2.141ArgAsp: 2.141 ± 1.347
3.854ArgGlu: 3.854 ± 0.826
2.998ArgPhe: 2.998 ± 1.424
6.424ArgGly: 6.424 ± 1.457
2.57ArgHis: 2.57 ± 0.852
1.285ArgIle: 1.285 ± 0.426
3.426ArgLys: 3.426 ± 1.141
6.852ArgLeu: 6.852 ± 1.66
0.857ArgMet: 0.857 ± 0.634
2.141ArgAsn: 2.141 ± 0.694
4.711ArgPro: 4.711 ± 1.492
2.998ArgGln: 2.998 ± 0.562
5.139ArgArg: 5.139 ± 2.186
5.567ArgSer: 5.567 ± 1.033
3.426ArgThr: 3.426 ± 1.541
3.854ArgVal: 3.854 ± 1.427
0.857ArgTrp: 0.857 ± 0.657
3.426ArgTyr: 3.426 ± 1.184
0.0ArgXaa: 0.0 ± 0.0
Ser
4.711SerAla: 4.711 ± 1.229
1.713SerCys: 1.713 ± 1.633
5.139SerAsp: 5.139 ± 0.813
3.854SerGlu: 3.854 ± 1.149
2.141SerPhe: 2.141 ± 0.641
7.281SerGly: 7.281 ± 1.43
1.713SerHis: 1.713 ± 0.76
3.426SerIle: 3.426 ± 1.05
1.285SerLys: 1.285 ± 0.64
8.565SerLeu: 8.565 ± 1.709
2.141SerMet: 2.141 ± 1.019
3.426SerAsn: 3.426 ± 1.006
4.711SerPro: 4.711 ± 1.596
1.713SerGln: 1.713 ± 0.608
7.281SerArg: 7.281 ± 1.044
7.281SerSer: 7.281 ± 1.58
7.709SerThr: 7.709 ± 2.487
2.998SerVal: 2.998 ± 1.374
0.857SerTrp: 0.857 ± 0.726
0.428SerTyr: 0.428 ± 0.353
0.0SerXaa: 0.0 ± 0.0
Thr
3.426ThrAla: 3.426 ± 1.361
0.428ThrCys: 0.428 ± 0.338
2.57ThrAsp: 2.57 ± 0.502
2.998ThrGlu: 2.998 ± 0.864
2.57ThrPhe: 2.57 ± 1.079
4.711ThrGly: 4.711 ± 1.504
1.285ThrHis: 1.285 ± 0.858
3.426ThrIle: 3.426 ± 1.382
2.141ThrLys: 2.141 ± 0.876
5.139ThrLeu: 5.139 ± 1.967
1.713ThrMet: 1.713 ± 1.004
1.713ThrAsn: 1.713 ± 0.577
5.139ThrPro: 5.139 ± 1.775
2.141ThrGln: 2.141 ± 0.689
4.283ThrArg: 4.283 ± 0.688
5.139ThrSer: 5.139 ± 1.361
2.998ThrThr: 2.998 ± 1.561
5.139ThrVal: 5.139 ± 1.583
0.428ThrTrp: 0.428 ± 0.378
1.713ThrTyr: 1.713 ± 0.573
0.428ThrXaa: 0.428 ± 0.338
Val
2.141ValAla: 2.141 ± 0.972
1.285ValCys: 1.285 ± 1.117
4.283ValAsp: 4.283 ± 0.688
4.283ValGlu: 4.283 ± 1.376
1.713ValPhe: 1.713 ± 0.792
2.998ValGly: 2.998 ± 1.55
0.857ValHis: 0.857 ± 0.732
4.283ValIle: 4.283 ± 1.745
0.857ValLys: 0.857 ± 0.412
5.996ValLeu: 5.996 ± 1.169
0.428ValMet: 0.428 ± 0.338
0.857ValAsn: 0.857 ± 0.442
6.852ValPro: 6.852 ± 1.909
1.713ValGln: 1.713 ± 1.004
3.854ValArg: 3.854 ± 1.1
6.424ValSer: 6.424 ± 2.754
4.283ValThr: 4.283 ± 1.186
2.998ValVal: 2.998 ± 1.172
1.285ValTrp: 1.285 ± 0.759
2.141ValTyr: 2.141 ± 0.752
0.0ValXaa: 0.0 ± 0.0
Trp
1.285TrpAla: 1.285 ± 0.718
0.857TrpCys: 0.857 ± 0.732
0.428TrpAsp: 0.428 ± 0.338
0.857TrpGlu: 0.857 ± 0.455
1.285TrpPhe: 1.285 ± 0.646
0.0TrpGly: 0.0 ± 0.0
0.857TrpHis: 0.857 ± 0.455
1.285TrpIle: 1.285 ± 0.696
2.57TrpLys: 2.57 ± 1.322
1.285TrpLeu: 1.285 ± 1.014
0.0TrpMet: 0.0 ± 0.0
0.428TrpAsn: 0.428 ± 0.353
0.0TrpPro: 0.0 ± 0.0
0.857TrpGln: 0.857 ± 0.757
0.857TrpArg: 0.857 ± 0.436
1.285TrpSer: 1.285 ± 0.728
0.857TrpThr: 0.857 ± 0.757
0.857TrpVal: 0.857 ± 0.676
0.0TrpTrp: 0.0 ± 0.0
0.428TrpTyr: 0.428 ± 0.656
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.857TyrAla: 0.857 ± 0.407
0.0TyrCys: 0.0 ± 0.0
0.857TyrAsp: 0.857 ± 0.51
3.854TyrGlu: 3.854 ± 1.159
2.57TyrPhe: 2.57 ± 0.875
1.713TyrGly: 1.713 ± 1.474
1.285TyrHis: 1.285 ± 0.37
1.285TyrIle: 1.285 ± 1.059
1.285TyrLys: 1.285 ± 0.71
3.854TyrLeu: 3.854 ± 0.868
0.428TyrMet: 0.428 ± 0.338
1.285TyrAsn: 1.285 ± 0.718
1.285TyrPro: 1.285 ± 0.757
1.713TyrGln: 1.713 ± 0.906
2.57TyrArg: 2.57 ± 1.407
1.713TyrSer: 1.713 ± 0.705
0.428TyrThr: 0.428 ± 0.338
1.285TyrVal: 1.285 ± 0.436
0.857TyrTrp: 0.857 ± 0.436
1.713TyrTyr: 1.713 ± 0.678
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.428XaaGln: 0.428 ± 0.338
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski