Amino acid dipepetide frequency for Pistachio ampelovirus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.364AlaAla: 4.364 ± 1.012
1.328AlaCys: 1.328 ± 0.683
3.416AlaAsp: 3.416 ± 0.661
2.846AlaGlu: 2.846 ± 0.973
1.708AlaPhe: 1.708 ± 0.296
2.277AlaGly: 2.277 ± 0.527
0.759AlaHis: 0.759 ± 0.312
4.364AlaIle: 4.364 ± 0.844
2.846AlaLys: 2.846 ± 0.655
7.021AlaLeu: 7.021 ± 1.124
1.518AlaMet: 1.518 ± 0.442
3.226AlaAsn: 3.226 ± 0.963
2.087AlaPro: 2.087 ± 0.786
1.328AlaGln: 1.328 ± 0.466
4.364AlaArg: 4.364 ± 0.923
4.554AlaSer: 4.554 ± 1.072
3.985AlaThr: 3.985 ± 1.16
4.175AlaVal: 4.175 ± 1.398
0.38AlaTrp: 0.38 ± 0.3
1.708AlaTyr: 1.708 ± 0.606
0.0AlaXaa: 0.0 ± 0.0
Cys
0.759CysAla: 0.759 ± 0.322
0.949CysCys: 0.949 ± 0.525
1.139CysAsp: 1.139 ± 0.532
0.949CysGlu: 0.949 ± 0.684
1.708CysPhe: 1.708 ± 0.468
0.569CysGly: 0.569 ± 0.5
0.38CysHis: 0.38 ± 0.273
1.139CysIle: 1.139 ± 0.539
1.139CysLys: 1.139 ± 0.377
1.518CysLeu: 1.518 ± 0.615
0.38CysMet: 0.38 ± 0.303
0.949CysAsn: 0.949 ± 0.372
0.38CysPro: 0.38 ± 0.274
0.19CysGln: 0.19 ± 0.137
0.38CysArg: 0.38 ± 0.213
1.898CysSer: 1.898 ± 0.594
1.328CysThr: 1.328 ± 0.746
2.277CysVal: 2.277 ± 0.897
0.0CysTrp: 0.0 ± 0.0
1.518CysTyr: 1.518 ± 0.619
0.0CysXaa: 0.0 ± 0.0
Asp
3.416AspAla: 3.416 ± 0.819
0.569AspCys: 0.569 ± 0.369
3.605AspAsp: 3.605 ± 1.083
4.175AspGlu: 4.175 ± 0.889
3.605AspPhe: 3.605 ± 0.881
2.657AspGly: 2.657 ± 0.713
0.949AspHis: 0.949 ± 0.362
5.693AspIle: 5.693 ± 1.017
3.416AspLys: 3.416 ± 0.777
4.364AspLeu: 4.364 ± 1.159
1.328AspMet: 1.328 ± 0.412
3.036AspAsn: 3.036 ± 0.767
1.139AspPro: 1.139 ± 0.436
0.569AspGln: 0.569 ± 0.426
4.744AspArg: 4.744 ± 1.073
5.123AspSer: 5.123 ± 1.295
2.467AspThr: 2.467 ± 0.872
6.641AspVal: 6.641 ± 0.622
0.569AspTrp: 0.569 ± 0.247
3.036AspTyr: 3.036 ± 1.209
0.0AspXaa: 0.0 ± 0.0
Glu
3.416GluAla: 3.416 ± 0.764
1.139GluCys: 1.139 ± 0.516
5.503GluAsp: 5.503 ± 0.854
5.503GluGlu: 5.503 ± 1.906
2.087GluPhe: 2.087 ± 0.614
3.226GluGly: 3.226 ± 1.351
1.139GluHis: 1.139 ± 0.45
3.605GluIle: 3.605 ± 0.886
3.226GluLys: 3.226 ± 0.974
7.78GluLeu: 7.78 ± 1.46
0.569GluMet: 0.569 ± 0.251
2.657GluAsn: 2.657 ± 0.999
1.139GluPro: 1.139 ± 0.544
1.518GluGln: 1.518 ± 0.477
4.175GluArg: 4.175 ± 1.088
4.175GluSer: 4.175 ± 0.821
2.846GluThr: 2.846 ± 0.611
6.262GluVal: 6.262 ± 1.061
1.139GluTrp: 1.139 ± 0.526
3.795GluTyr: 3.795 ± 0.865
0.0GluXaa: 0.0 ± 0.0
Phe
2.277PheAla: 2.277 ± 0.635
0.949PheCys: 0.949 ± 0.374
3.605PheAsp: 3.605 ± 0.67
3.605PheGlu: 3.605 ± 0.712
2.277PhePhe: 2.277 ± 0.754
2.087PheGly: 2.087 ± 0.612
0.569PheHis: 0.569 ± 0.26
1.708PheIle: 1.708 ± 0.494
2.467PheLys: 2.467 ± 0.601
5.882PheLeu: 5.882 ± 1.527
0.949PheMet: 0.949 ± 0.47
0.759PheAsn: 0.759 ± 0.371
0.569PhePro: 0.569 ± 0.247
0.569PheGln: 0.569 ± 0.211
3.226PheArg: 3.226 ± 0.694
5.503PheSer: 5.503 ± 1.121
2.657PheThr: 2.657 ± 0.644
3.605PheVal: 3.605 ± 0.916
0.19PheTrp: 0.19 ± 0.203
1.898PheTyr: 1.898 ± 1.059
0.0PheXaa: 0.0 ± 0.0
Gly
5.503GlyAla: 5.503 ± 0.653
1.328GlyCys: 1.328 ± 0.315
3.795GlyAsp: 3.795 ± 0.702
2.657GlyGlu: 2.657 ± 0.576
2.277GlyPhe: 2.277 ± 0.559
4.744GlyGly: 4.744 ± 1.346
0.569GlyHis: 0.569 ± 0.288
2.277GlyIle: 2.277 ± 0.696
4.744GlyLys: 4.744 ± 1.873
3.416GlyLeu: 3.416 ± 1.051
0.759GlyMet: 0.759 ± 0.294
4.175GlyAsn: 4.175 ± 1.069
1.139GlyPro: 1.139 ± 0.435
1.328GlyGln: 1.328 ± 0.392
2.846GlyArg: 2.846 ± 1.199
4.934GlySer: 4.934 ± 1.061
3.036GlyThr: 3.036 ± 0.742
3.226GlyVal: 3.226 ± 0.953
0.19GlyTrp: 0.19 ± 0.214
2.657GlyTyr: 2.657 ± 0.848
0.0GlyXaa: 0.0 ± 0.0
His
1.708HisAla: 1.708 ± 0.576
0.38HisCys: 0.38 ± 0.338
0.949HisAsp: 0.949 ± 0.425
1.139HisGlu: 1.139 ± 0.527
0.949HisPhe: 0.949 ± 0.307
1.328HisGly: 1.328 ± 0.432
0.38HisHis: 0.38 ± 0.18
0.759HisIle: 0.759 ± 0.316
0.569HisLys: 0.569 ± 0.211
2.277HisLeu: 2.277 ± 0.49
0.38HisMet: 0.38 ± 0.322
0.949HisAsn: 0.949 ± 0.441
0.38HisPro: 0.38 ± 0.213
0.19HisGln: 0.19 ± 0.137
1.328HisArg: 1.328 ± 0.35
1.139HisSer: 1.139 ± 0.523
0.949HisThr: 0.949 ± 0.335
1.139HisVal: 1.139 ± 0.285
0.0HisTrp: 0.0 ± 0.0
0.19HisTyr: 0.19 ± 0.137
0.0HisXaa: 0.0 ± 0.0
Ile
3.605IleAla: 3.605 ± 1.036
0.759IleCys: 0.759 ± 0.365
2.657IleAsp: 2.657 ± 0.792
3.985IleGlu: 3.985 ± 0.864
3.036IlePhe: 3.036 ± 0.557
2.657IleGly: 2.657 ± 0.836
1.328IleHis: 1.328 ± 0.299
4.175IleIle: 4.175 ± 0.848
1.518IleLys: 1.518 ± 0.337
6.262IleLeu: 6.262 ± 1.53
1.518IleMet: 1.518 ± 0.482
5.123IleAsn: 5.123 ± 1.196
1.328IlePro: 1.328 ± 0.301
0.949IleGln: 0.949 ± 0.521
3.605IleArg: 3.605 ± 1.257
6.831IleSer: 6.831 ± 0.798
2.657IleThr: 2.657 ± 0.963
6.452IleVal: 6.452 ± 1.198
0.0IleTrp: 0.0 ± 0.0
2.657IleTyr: 2.657 ± 0.701
0.0IleXaa: 0.0 ± 0.0
Lys
2.657LysAla: 2.657 ± 0.91
1.328LysCys: 1.328 ± 0.533
4.175LysAsp: 4.175 ± 0.93
3.416LysGlu: 3.416 ± 0.879
2.846LysPhe: 2.846 ± 0.623
3.605LysGly: 3.605 ± 0.73
2.087LysHis: 2.087 ± 0.734
3.226LysIle: 3.226 ± 0.708
4.175LysLys: 4.175 ± 1.713
5.693LysLeu: 5.693 ± 1.318
1.518LysMet: 1.518 ± 0.72
2.087LysAsn: 2.087 ± 0.812
3.416LysPro: 3.416 ± 1.183
1.139LysGln: 1.139 ± 0.455
2.467LysArg: 2.467 ± 0.626
4.554LysSer: 4.554 ± 0.771
4.554LysThr: 4.554 ± 1.181
6.072LysVal: 6.072 ± 1.226
0.0LysTrp: 0.0 ± 0.0
3.416LysTyr: 3.416 ± 0.855
0.0LysXaa: 0.0 ± 0.0
Leu
5.693LeuAla: 5.693 ± 1.256
2.087LeuCys: 2.087 ± 0.59
4.554LeuAsp: 4.554 ± 1.473
6.452LeuGlu: 6.452 ± 1.171
5.123LeuPhe: 5.123 ± 1.208
4.934LeuGly: 4.934 ± 1.64
1.898LeuHis: 1.898 ± 0.625
7.4LeuIle: 7.4 ± 1.667
7.97LeuLys: 7.97 ± 1.727
5.313LeuLeu: 5.313 ± 1.376
2.087LeuMet: 2.087 ± 0.672
5.693LeuAsn: 5.693 ± 1.265
3.416LeuPro: 3.416 ± 0.874
2.277LeuGln: 2.277 ± 0.594
7.021LeuArg: 7.021 ± 1.121
10.057LeuSer: 10.057 ± 1.88
5.882LeuThr: 5.882 ± 1.396
5.313LeuVal: 5.313 ± 0.867
1.518LeuTrp: 1.518 ± 0.419
2.657LeuTyr: 2.657 ± 0.449
0.0LeuXaa: 0.0 ± 0.0
Met
1.518MetAla: 1.518 ± 0.606
0.949MetCys: 0.949 ± 0.375
0.949MetAsp: 0.949 ± 0.461
1.328MetGlu: 1.328 ± 0.577
0.949MetPhe: 0.949 ± 0.561
0.759MetGly: 0.759 ± 0.373
0.19MetHis: 0.19 ± 0.137
1.328MetIle: 1.328 ± 0.783
0.759MetLys: 0.759 ± 0.434
1.898MetLeu: 1.898 ± 0.568
0.38MetMet: 0.38 ± 0.319
1.518MetAsn: 1.518 ± 0.64
0.569MetPro: 0.569 ± 0.393
0.759MetGln: 0.759 ± 0.31
0.949MetArg: 0.949 ± 0.416
1.898MetSer: 1.898 ± 0.524
1.139MetThr: 1.139 ± 0.458
0.38MetVal: 0.38 ± 0.269
0.0MetTrp: 0.0 ± 0.0
0.569MetTyr: 0.569 ± 0.41
0.0MetXaa: 0.0 ± 0.0
Asn
2.087AsnAla: 2.087 ± 0.583
0.569AsnCys: 0.569 ± 0.378
3.036AsnAsp: 3.036 ± 0.79
4.364AsnGlu: 4.364 ± 0.69
2.467AsnPhe: 2.467 ± 0.881
2.657AsnGly: 2.657 ± 0.76
0.949AsnHis: 0.949 ± 0.357
3.605AsnIle: 3.605 ± 1.025
2.467AsnLys: 2.467 ± 0.627
5.693AsnLeu: 5.693 ± 0.997
0.38AsnMet: 0.38 ± 0.338
1.898AsnAsn: 1.898 ± 0.583
1.518AsnPro: 1.518 ± 0.613
1.328AsnGln: 1.328 ± 0.388
2.846AsnArg: 2.846 ± 1.154
3.985AsnSer: 3.985 ± 1.051
3.795AsnThr: 3.795 ± 0.819
5.503AsnVal: 5.503 ± 1.211
0.759AsnTrp: 0.759 ± 0.294
2.657AsnTyr: 2.657 ± 1.055
0.0AsnXaa: 0.0 ± 0.0
Pro
1.898ProAla: 1.898 ± 0.704
0.19ProCys: 0.19 ± 0.169
0.949ProAsp: 0.949 ± 0.303
2.087ProGlu: 2.087 ± 0.686
1.708ProPhe: 1.708 ± 0.389
1.518ProGly: 1.518 ± 0.446
0.19ProHis: 0.19 ± 0.203
1.328ProIle: 1.328 ± 0.59
1.708ProLys: 1.708 ± 0.573
2.846ProLeu: 2.846 ± 0.82
0.759ProMet: 0.759 ± 0.29
1.139ProAsn: 1.139 ± 0.523
0.759ProPro: 0.759 ± 0.404
1.139ProGln: 1.139 ± 0.438
1.518ProArg: 1.518 ± 0.577
2.467ProSer: 2.467 ± 0.745
3.226ProThr: 3.226 ± 0.754
2.087ProVal: 2.087 ± 0.41
0.0ProTrp: 0.0 ± 0.0
1.518ProTyr: 1.518 ± 0.658
0.0ProXaa: 0.0 ± 0.0
Gln
1.139GlnAla: 1.139 ± 0.468
0.569GlnCys: 0.569 ± 0.266
1.328GlnAsp: 1.328 ± 0.441
1.518GlnGlu: 1.518 ± 0.545
0.759GlnPhe: 0.759 ± 0.473
1.708GlnGly: 1.708 ± 0.415
0.569GlnHis: 0.569 ± 0.266
1.328GlnIle: 1.328 ± 0.512
1.518GlnLys: 1.518 ± 0.569
1.898GlnLeu: 1.898 ± 0.695
0.38GlnMet: 0.38 ± 0.261
0.569GlnAsn: 0.569 ± 0.364
0.759GlnPro: 0.759 ± 0.378
0.759GlnGln: 0.759 ± 0.504
1.139GlnArg: 1.139 ± 0.56
1.518GlnSer: 1.518 ± 0.781
1.139GlnThr: 1.139 ± 0.345
2.087GlnVal: 2.087 ± 0.624
0.19GlnTrp: 0.19 ± 0.203
1.328GlnTyr: 1.328 ± 0.784
0.0GlnXaa: 0.0 ± 0.0
Arg
3.036ArgAla: 3.036 ± 0.604
1.328ArgCys: 1.328 ± 0.691
2.277ArgAsp: 2.277 ± 0.882
3.795ArgGlu: 3.795 ± 0.692
1.898ArgPhe: 1.898 ± 0.499
3.036ArgGly: 3.036 ± 0.905
0.38ArgHis: 0.38 ± 0.225
2.846ArgIle: 2.846 ± 0.93
4.554ArgLys: 4.554 ± 0.695
6.831ArgLeu: 6.831 ± 0.353
1.328ArgMet: 1.328 ± 0.526
4.364ArgAsn: 4.364 ± 0.781
1.328ArgPro: 1.328 ± 0.402
1.518ArgGln: 1.518 ± 0.903
5.123ArgArg: 5.123 ± 1.216
3.605ArgSer: 3.605 ± 0.889
4.554ArgThr: 4.554 ± 0.97
4.744ArgVal: 4.744 ± 0.834
0.38ArgTrp: 0.38 ± 0.21
2.277ArgTyr: 2.277 ± 0.433
0.0ArgXaa: 0.0 ± 0.0
Ser
3.985SerAla: 3.985 ± 1.01
1.518SerCys: 1.518 ± 0.524
6.831SerAsp: 6.831 ± 1.185
5.123SerGlu: 5.123 ± 1.204
3.416SerPhe: 3.416 ± 0.807
4.934SerGly: 4.934 ± 0.763
0.759SerHis: 0.759 ± 0.481
5.882SerIle: 5.882 ± 1.315
7.97SerLys: 7.97 ± 1.143
7.59SerLeu: 7.59 ± 0.988
1.898SerMet: 1.898 ± 0.678
4.175SerAsn: 4.175 ± 1.014
3.036SerPro: 3.036 ± 0.425
2.846SerGln: 2.846 ± 0.966
3.226SerArg: 3.226 ± 0.693
6.831SerSer: 6.831 ± 1.071
4.554SerThr: 4.554 ± 0.576
5.123SerVal: 5.123 ± 0.849
0.569SerTrp: 0.569 ± 0.303
3.036SerTyr: 3.036 ± 0.726
0.0SerXaa: 0.0 ± 0.0
Thr
2.657ThrAla: 2.657 ± 0.437
1.328ThrCys: 1.328 ± 0.552
3.605ThrAsp: 3.605 ± 0.891
3.036ThrGlu: 3.036 ± 0.493
2.846ThrPhe: 2.846 ± 0.345
5.123ThrGly: 5.123 ± 1.323
1.328ThrHis: 1.328 ± 0.391
2.846ThrIle: 2.846 ± 1.035
3.416ThrLys: 3.416 ± 0.973
6.452ThrLeu: 6.452 ± 1.236
0.19ThrMet: 0.19 ± 0.308
3.985ThrAsn: 3.985 ± 0.876
2.467ThrPro: 2.467 ± 1.445
1.518ThrGln: 1.518 ± 0.494
3.226ThrArg: 3.226 ± 0.749
5.123ThrSer: 5.123 ± 0.829
2.846ThrThr: 2.846 ± 1.152
5.123ThrVal: 5.123 ± 1.185
0.759ThrTrp: 0.759 ± 0.516
2.087ThrTyr: 2.087 ± 0.736
0.0ThrXaa: 0.0 ± 0.0
Val
6.072ValAla: 6.072 ± 1.797
1.328ValCys: 1.328 ± 0.327
5.503ValAsp: 5.503 ± 0.645
5.313ValGlu: 5.313 ± 1.059
3.226ValPhe: 3.226 ± 1.694
4.175ValGly: 4.175 ± 1.019
1.898ValHis: 1.898 ± 0.666
4.554ValIle: 4.554 ± 0.876
4.554ValLys: 4.554 ± 0.802
7.97ValLeu: 7.97 ± 1.195
1.328ValMet: 1.328 ± 0.411
4.554ValAsn: 4.554 ± 0.528
3.036ValPro: 3.036 ± 0.829
1.328ValGln: 1.328 ± 0.863
4.554ValArg: 4.554 ± 1.111
6.072ValSer: 6.072 ± 1.04
6.072ValThr: 6.072 ± 1.052
7.78ValVal: 7.78 ± 2.236
0.569ValTrp: 0.569 ± 0.368
2.846ValTyr: 2.846 ± 1.007
0.0ValXaa: 0.0 ± 0.0
Trp
0.569TrpAla: 0.569 ± 0.294
0.19TrpCys: 0.19 ± 0.216
0.19TrpAsp: 0.19 ± 0.203
0.569TrpGlu: 0.569 ± 0.25
0.569TrpPhe: 0.569 ± 0.525
0.38TrpGly: 0.38 ± 0.225
0.0TrpHis: 0.0 ± 0.0
0.759TrpIle: 0.759 ± 0.506
0.569TrpLys: 0.569 ± 0.294
1.139TrpLeu: 1.139 ± 0.37
0.0TrpMet: 0.0 ± 0.0
0.38TrpAsn: 0.38 ± 0.335
0.0TrpPro: 0.0 ± 0.0
0.19TrpGln: 0.19 ± 0.214
0.38TrpArg: 0.38 ± 0.288
0.0TrpSer: 0.0 ± 0.0
0.19TrpThr: 0.19 ± 0.184
0.759TrpVal: 0.759 ± 0.307
0.19TrpTrp: 0.19 ± 0.238
0.38TrpTyr: 0.38 ± 0.269
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.898TyrAla: 1.898 ± 0.721
0.759TyrCys: 0.759 ± 0.368
3.036TyrAsp: 3.036 ± 0.898
3.036TyrGlu: 3.036 ± 0.955
1.898TyrPhe: 1.898 ± 0.597
3.226TyrGly: 3.226 ± 0.856
0.759TyrHis: 0.759 ± 0.41
2.277TyrIle: 2.277 ± 0.572
2.846TyrLys: 2.846 ± 0.438
5.503TyrLeu: 5.503 ± 1.369
0.949TyrMet: 0.949 ± 0.412
1.328TyrAsn: 1.328 ± 0.633
0.569TyrPro: 0.569 ± 0.248
0.759TyrGln: 0.759 ± 0.335
2.087TyrArg: 2.087 ± 0.852
3.036TyrSer: 3.036 ± 1.337
2.277TyrThr: 2.277 ± 0.691
3.985TyrVal: 3.985 ± 1.046
0.0TyrTrp: 0.0 ± 0.0
1.898TyrTyr: 1.898 ± 0.758
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (5271 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski