Amino acid dipepetide frequency for Limeum africanum associated virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.852AlaAla: 2.852 ± 1.047
1.901AlaCys: 1.901 ± 1.096
3.802AlaAsp: 3.802 ± 1.548
2.852AlaGlu: 2.852 ± 1.047
0.0AlaPhe: 0.0 ± 0.0
1.901AlaGly: 1.901 ± 0.916
0.0AlaHis: 0.0 ± 0.0
0.0AlaIle: 0.0 ± 0.0
1.901AlaLys: 1.901 ± 0.774
3.802AlaLeu: 3.802 ± 1.647
0.951AlaMet: 0.951 ± 0.823
1.901AlaAsn: 1.901 ± 0.774
2.852AlaPro: 2.852 ± 1.675
5.703AlaGln: 5.703 ± 2.303
0.951AlaArg: 0.951 ± 0.67
5.703AlaSer: 5.703 ± 1.053
2.852AlaThr: 2.852 ± 0.597
1.901AlaVal: 1.901 ± 1.645
0.951AlaTrp: 0.951 ± 0.67
1.901AlaTyr: 1.901 ± 1.096
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.901CysGlu: 1.901 ± 1.949
0.0CysPhe: 0.0 ± 0.0
0.951CysGly: 0.951 ± 0.67
0.0CysHis: 0.0 ± 0.0
0.951CysIle: 0.951 ± 0.975
0.951CysLys: 0.951 ± 0.67
2.852CysLeu: 2.852 ± 1.047
0.951CysMet: 0.951 ± 1.072
1.901CysAsn: 1.901 ± 0.824
2.852CysPro: 2.852 ± 0.597
4.753CysGln: 4.753 ± 1.562
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.951CysThr: 0.951 ± 0.975
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.901CysTyr: 1.901 ± 0.774
0.0CysXaa: 0.0 ± 0.0
Asp
3.802AspAla: 3.802 ± 1.141
0.951AspCys: 0.951 ± 0.823
2.852AspAsp: 2.852 ± 1.256
1.901AspGlu: 1.901 ± 1.592
4.753AspPhe: 4.753 ± 1.784
3.802AspGly: 3.802 ± 0.653
0.0AspHis: 0.0 ± 0.0
3.802AspIle: 3.802 ± 0.879
2.852AspLys: 2.852 ± 1.504
1.901AspLeu: 1.901 ± 1.183
1.901AspMet: 1.901 ± 0.824
1.901AspAsn: 1.901 ± 1.645
1.901AspPro: 1.901 ± 0.774
4.753AspGln: 4.753 ± 1.784
0.951AspArg: 0.951 ± 0.823
1.901AspSer: 1.901 ± 1.096
6.654AspThr: 6.654 ± 1.214
3.802AspVal: 3.802 ± 0.653
1.901AspTrp: 1.901 ± 1.121
5.703AspTyr: 5.703 ± 1.437
0.0AspXaa: 0.0 ± 0.0
Glu
1.901GluAla: 1.901 ± 1.949
0.0GluCys: 0.0 ± 0.0
4.753GluAsp: 4.753 ± 2.749
10.456GluGlu: 10.456 ± 7.635
3.802GluPhe: 3.802 ± 2.168
3.802GluGly: 3.802 ± 2.241
0.0GluHis: 0.0 ± 0.0
2.852GluIle: 2.852 ± 1.086
3.802GluLys: 3.802 ± 1.3
5.703GluLeu: 5.703 ± 2.801
0.0GluMet: 0.0 ± 0.0
2.852GluAsn: 2.852 ± 0.597
5.703GluPro: 5.703 ± 2.322
0.951GluGln: 0.951 ± 1.072
2.852GluArg: 2.852 ± 0.597
3.802GluSer: 3.802 ± 1.869
2.852GluThr: 2.852 ± 1.521
1.901GluVal: 1.901 ± 1.183
2.852GluTrp: 2.852 ± 1.047
1.901GluTyr: 1.901 ± 0.774
0.0GluXaa: 0.0 ± 0.0
Phe
0.951PheAla: 0.951 ± 1.072
0.951PheCys: 0.951 ± 0.67
3.802PheAsp: 3.802 ± 1.212
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
2.852PheGly: 2.852 ± 1.893
1.901PheHis: 1.901 ± 1.096
3.802PheIle: 3.802 ± 1.682
0.951PheLys: 0.951 ± 0.975
5.703PheLeu: 5.703 ± 1.563
0.951PheMet: 0.951 ± 0.62
3.802PheAsn: 3.802 ± 1.548
1.901PhePro: 1.901 ± 1.096
0.951PheGln: 0.951 ± 0.67
2.852PheArg: 2.852 ± 0.597
3.802PheSer: 3.802 ± 1.304
2.852PheThr: 2.852 ± 1.209
1.901PheVal: 1.901 ± 0.774
0.951PheTrp: 0.951 ± 0.823
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.0GlyAla: 0.0 ± 0.0
0.951GlyCys: 0.951 ± 0.975
0.951GlyAsp: 0.951 ± 0.823
2.852GlyGlu: 2.852 ± 1.047
1.901GlyPhe: 1.901 ± 1.299
9.506GlyGly: 9.506 ± 1.869
0.0GlyHis: 0.0 ± 0.0
5.703GlyIle: 5.703 ± 2.331
4.753GlyLys: 4.753 ± 1.199
0.951GlyLeu: 0.951 ± 1.072
1.901GlyMet: 1.901 ± 1.829
3.802GlyAsn: 3.802 ± 1.212
4.753GlyPro: 4.753 ± 0.928
2.852GlyGln: 2.852 ± 1.086
2.852GlyArg: 2.852 ± 1.209
3.802GlySer: 3.802 ± 1.38
2.852GlyThr: 2.852 ± 1.485
3.802GlyVal: 3.802 ± 0.879
0.951GlyTrp: 0.951 ± 0.796
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.901HisCys: 1.901 ± 0.774
0.951HisAsp: 0.951 ± 0.67
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
4.753HisLeu: 4.753 ± 1.332
0.951HisMet: 0.951 ± 0.716
3.802HisAsn: 3.802 ± 0.879
2.852HisPro: 2.852 ± 1.42
1.901HisGln: 1.901 ± 0.774
0.951HisArg: 0.951 ± 0.67
1.901HisSer: 1.901 ± 1.248
1.901HisThr: 1.901 ± 1.446
2.852HisVal: 2.852 ± 1.209
0.951HisTrp: 0.951 ± 0.823
1.901HisTyr: 1.901 ± 0.774
0.0HisXaa: 0.0 ± 0.0
Ile
2.852IleAla: 2.852 ± 1.086
1.901IleCys: 1.901 ± 0.774
3.802IleAsp: 3.802 ± 1.548
0.0IleGlu: 0.0 ± 0.0
3.802IlePhe: 3.802 ± 0.895
2.852IleGly: 2.852 ± 1.549
0.0IleHis: 0.0 ± 0.0
3.802IleIle: 3.802 ± 1.548
2.852IleLys: 2.852 ± 1.209
4.753IleLeu: 4.753 ± 1.562
0.0IleMet: 0.0 ± 0.0
1.901IleAsn: 1.901 ± 0.916
2.852IlePro: 2.852 ± 1.256
3.802IleGln: 3.802 ± 1.291
5.703IleArg: 5.703 ± 1.422
3.802IleSer: 3.802 ± 2.014
1.901IleThr: 1.901 ± 0.824
1.901IleVal: 1.901 ± 0.824
1.901IleTrp: 1.901 ± 0.774
1.901IleTyr: 1.901 ± 0.824
0.0IleXaa: 0.0 ± 0.0
Lys
2.852LysAla: 2.852 ± 2.468
0.951LysCys: 0.951 ± 0.975
5.703LysAsp: 5.703 ± 1.194
5.703LysGlu: 5.703 ± 1.508
3.802LysPhe: 3.802 ± 0.653
3.802LysGly: 3.802 ± 1.304
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
11.407LysLys: 11.407 ± 3.197
4.753LysLeu: 4.753 ± 1.507
0.951LysMet: 0.951 ± 0.823
0.0LysAsn: 0.0 ± 0.0
0.951LysPro: 0.951 ± 0.823
0.951LysGln: 0.951 ± 0.823
5.703LysArg: 5.703 ± 1.858
3.802LysSer: 3.802 ± 1.548
3.802LysThr: 3.802 ± 1.647
1.901LysVal: 1.901 ± 1.949
3.802LysTrp: 3.802 ± 1.212
4.753LysTyr: 4.753 ± 1.954
0.0LysXaa: 0.0 ± 0.0
Leu
2.852LeuAla: 2.852 ± 1.926
0.951LeuCys: 0.951 ± 0.67
0.951LeuAsp: 0.951 ± 0.975
4.753LeuGlu: 4.753 ± 2.791
5.703LeuPhe: 5.703 ± 1.809
3.802LeuGly: 3.802 ± 1.3
4.753LeuHis: 4.753 ± 2.241
4.753LeuIle: 4.753 ± 1.917
4.753LeuLys: 4.753 ± 1.054
7.605LeuLeu: 7.605 ± 1.307
2.852LeuMet: 2.852 ± 1.504
8.555LeuAsn: 8.555 ± 3.654
0.951LeuPro: 0.951 ± 0.67
6.654LeuGln: 6.654 ± 2.868
3.802LeuArg: 3.802 ± 1.548
2.852LeuSer: 2.852 ± 2.236
1.901LeuThr: 1.901 ± 0.774
1.901LeuVal: 1.901 ± 1.299
0.0LeuTrp: 0.0 ± 0.0
5.703LeuTyr: 5.703 ± 0.816
0.0LeuXaa: 0.0 ± 0.0
Met
3.802MetAla: 3.802 ± 2.4
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.951MetGlu: 0.951 ± 0.975
0.0MetPhe: 0.0 ± 0.0
0.951MetGly: 0.951 ± 0.67
0.0MetHis: 0.0 ± 0.0
0.951MetIle: 0.951 ± 0.823
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.951MetMet: 0.951 ± 0.67
0.951MetAsn: 0.951 ± 0.823
3.802MetPro: 3.802 ± 0.895
0.951MetGln: 0.951 ± 0.67
0.0MetArg: 0.0 ± 0.0
0.951MetSer: 0.951 ± 0.823
1.901MetThr: 1.901 ± 1.645
1.901MetVal: 1.901 ± 1.299
0.0MetTrp: 0.0 ± 0.0
1.901MetTyr: 1.901 ± 0.824
0.0MetXaa: 0.0 ± 0.0
Asn
0.951AsnAla: 0.951 ± 0.823
1.901AsnCys: 1.901 ± 0.774
4.753AsnAsp: 4.753 ± 1.757
3.802AsnGlu: 3.802 ± 0.879
3.802AsnPhe: 3.802 ± 0.653
0.951AsnGly: 0.951 ± 0.823
2.852AsnHis: 2.852 ± 0.597
4.753AsnIle: 4.753 ± 1.983
0.951AsnLys: 0.951 ± 0.975
5.703AsnLeu: 5.703 ± 2.322
0.0AsnMet: 0.0 ± 0.0
1.901AsnAsn: 1.901 ± 1.645
2.852AsnPro: 2.852 ± 1.209
4.753AsnGln: 4.753 ± 1.111
2.852AsnArg: 2.852 ± 0.597
1.901AsnSer: 1.901 ± 0.774
3.802AsnThr: 3.802 ± 1.212
5.703AsnVal: 5.703 ± 1.518
0.951AsnTrp: 0.951 ± 0.67
3.802AsnTyr: 3.802 ± 2.28
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
2.852ProCys: 2.852 ± 1.209
3.802ProAsp: 3.802 ± 1.262
4.753ProGlu: 4.753 ± 2.198
1.901ProPhe: 1.901 ± 0.824
0.0ProGly: 0.0 ± 0.0
2.852ProHis: 2.852 ± 1.209
0.951ProIle: 0.951 ± 0.67
2.852ProLys: 2.852 ± 1.047
3.802ProLeu: 3.802 ± 1.548
0.0ProMet: 0.0 ± 0.0
7.605ProAsn: 7.605 ± 2.423
3.802ProPro: 3.802 ± 1.548
1.901ProGln: 1.901 ± 0.774
6.654ProArg: 6.654 ± 2.199
4.753ProSer: 4.753 ± 1.054
2.852ProThr: 2.852 ± 1.504
3.802ProVal: 3.802 ± 1.141
0.0ProTrp: 0.0 ± 0.0
2.852ProTyr: 2.852 ± 1.047
0.0ProXaa: 0.0 ± 0.0
Gln
1.901GlnAla: 1.901 ± 1.645
1.901GlnCys: 1.901 ± 0.774
2.852GlnAsp: 2.852 ± 1.209
6.654GlnGlu: 6.654 ± 2.761
0.951GlnPhe: 0.951 ± 0.975
4.753GlnGly: 4.753 ± 1.054
2.852GlnHis: 2.852 ± 1.209
0.0GlnIle: 0.0 ± 0.0
4.753GlnLys: 4.753 ± 1.548
6.654GlnLeu: 6.654 ± 1.539
0.0GlnMet: 0.0 ± 0.0
0.951GlnAsn: 0.951 ± 0.67
3.802GlnPro: 3.802 ± 1.548
0.0GlnGln: 0.0 ± 0.0
1.901GlnArg: 1.901 ± 0.824
3.802GlnSer: 3.802 ± 2.014
3.802GlnThr: 3.802 ± 0.653
3.802GlnVal: 3.802 ± 0.895
1.901GlnTrp: 1.901 ± 1.096
1.901GlnTyr: 1.901 ± 0.824
0.0GlnXaa: 0.0 ± 0.0
Arg
2.852ArgAla: 2.852 ± 0.597
0.951ArgCys: 0.951 ± 0.975
6.654ArgAsp: 6.654 ± 0.785
0.0ArgGlu: 0.0 ± 0.0
0.951ArgPhe: 0.951 ± 0.823
2.852ArgGly: 2.852 ± 1.086
2.852ArgHis: 2.852 ± 1.161
3.802ArgIle: 3.802 ± 0.879
5.703ArgLys: 5.703 ± 3.89
2.852ArgLeu: 2.852 ± 1.42
0.951ArgMet: 0.951 ± 0.884
4.753ArgAsn: 4.753 ± 1.111
2.852ArgPro: 2.852 ± 1.504
1.901ArgGln: 1.901 ± 0.774
5.703ArgArg: 5.703 ± 2.929
1.901ArgSer: 1.901 ± 0.824
4.753ArgThr: 4.753 ± 1.111
3.802ArgVal: 3.802 ± 1.291
1.901ArgTrp: 1.901 ± 0.774
1.901ArgTyr: 1.901 ± 0.774
0.0ArgXaa: 0.0 ± 0.0
Ser
0.951SerAla: 0.951 ± 0.823
0.0SerCys: 0.0 ± 0.0
3.802SerAsp: 3.802 ± 1.548
2.852SerGlu: 2.852 ± 2.221
1.901SerPhe: 1.901 ± 0.774
5.703SerGly: 5.703 ± 1.187
0.0SerHis: 0.0 ± 0.0
5.703SerIle: 5.703 ± 2.093
4.753SerLys: 4.753 ± 1.552
3.802SerLeu: 3.802 ± 3.124
2.852SerMet: 2.852 ± 1.06
4.753SerAsn: 4.753 ± 1.199
1.901SerPro: 1.901 ± 0.774
1.901SerGln: 1.901 ± 0.824
2.852SerArg: 2.852 ± 1.086
4.753SerSer: 4.753 ± 3.496
6.654SerThr: 6.654 ± 1.724
1.901SerVal: 1.901 ± 2.144
1.901SerTrp: 1.901 ± 1.096
0.951SerTyr: 0.951 ± 0.67
0.0SerXaa: 0.0 ± 0.0
Thr
2.852ThrAla: 2.852 ± 1.504
0.951ThrCys: 0.951 ± 0.975
0.951ThrAsp: 0.951 ± 0.823
3.802ThrGlu: 3.802 ± 1.291
2.852ThrPhe: 2.852 ± 0.597
3.802ThrGly: 3.802 ± 2.28
2.852ThrHis: 2.852 ± 0.597
4.753ThrIle: 4.753 ± 0.935
2.852ThrLys: 2.852 ± 1.926
0.951ThrLeu: 0.951 ± 0.67
1.901ThrMet: 1.901 ± 0.824
0.951ThrAsn: 0.951 ± 0.823
1.901ThrPro: 1.901 ± 1.248
4.753ThrGln: 4.753 ± 1.111
5.703ThrArg: 5.703 ± 0.922
5.703ThrSer: 5.703 ± 1.721
2.852ThrThr: 2.852 ± 2.468
3.802ThrVal: 3.802 ± 0.895
1.901ThrTrp: 1.901 ± 1.299
4.753ThrTyr: 4.753 ± 1.054
0.0ThrXaa: 0.0 ± 0.0
Val
1.901ValAla: 1.901 ± 0.774
0.951ValCys: 0.951 ± 1.072
2.852ValAsp: 2.852 ± 1.504
3.802ValGlu: 3.802 ± 1.632
0.951ValPhe: 0.951 ± 1.072
0.951ValGly: 0.951 ± 1.072
1.901ValHis: 1.901 ± 0.774
3.802ValIle: 3.802 ± 1.548
5.703ValLys: 5.703 ± 4.936
2.852ValLeu: 2.852 ± 1.086
0.0ValMet: 0.0 ± 0.0
3.802ValAsn: 3.802 ± 1.445
3.802ValPro: 3.802 ± 1.548
3.802ValGln: 3.802 ± 0.895
3.802ValArg: 3.802 ± 2.149
2.852ValSer: 2.852 ± 1.086
2.852ValThr: 2.852 ± 0.597
2.852ValVal: 2.852 ± 1.893
1.901ValTrp: 1.901 ± 0.774
1.901ValTyr: 1.901 ± 0.774
0.0ValXaa: 0.0 ± 0.0
Trp
7.605TrpAla: 7.605 ± 3.095
0.0TrpCys: 0.0 ± 0.0
1.901TrpAsp: 1.901 ± 1.121
0.951TrpGlu: 0.951 ± 0.975
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.901TrpHis: 1.901 ± 0.774
0.0TrpIle: 0.0 ± 0.0
0.951TrpLys: 0.951 ± 0.823
1.901TrpLeu: 1.901 ± 1.299
0.0TrpMet: 0.0 ± 0.0
1.901TrpAsn: 1.901 ± 1.949
2.852TrpPro: 2.852 ± 0.597
0.951TrpGln: 0.951 ± 0.823
0.951TrpArg: 0.951 ± 0.823
1.901TrpSer: 1.901 ± 0.824
0.951TrpThr: 0.951 ± 0.823
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.802TyrAla: 3.802 ± 0.879
0.951TyrCys: 0.951 ± 0.975
2.852TyrAsp: 2.852 ± 1.256
4.753TyrGlu: 4.753 ± 1.111
3.802TyrPhe: 3.802 ± 0.879
2.852TyrGly: 2.852 ± 1.485
2.852TyrHis: 2.852 ± 0.597
1.901TyrIle: 1.901 ± 0.774
2.852TyrLys: 2.852 ± 1.504
4.753TyrLeu: 4.753 ± 1.954
0.951TyrMet: 0.951 ± 0.823
0.951TyrAsn: 0.951 ± 0.67
2.852TyrPro: 2.852 ± 1.047
0.951TyrGln: 0.951 ± 0.823
2.852TyrArg: 2.852 ± 0.966
0.0TyrSer: 0.0 ± 0.0
1.901TyrThr: 1.901 ± 0.774
3.802TyrVal: 3.802 ± 1.212
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1053 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski