Amino acid dipepetide frequency for Shahe hepe-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.552AlaAla: 6.552 ± 2.542
1.56AlaCys: 1.56 ± 1.213
3.744AlaAsp: 3.744 ± 0.652
4.056AlaGlu: 4.056 ± 0.941
3.744AlaPhe: 3.744 ± 1.135
3.12AlaGly: 3.12 ± 0.665
1.248AlaHis: 1.248 ± 0.616
4.056AlaIle: 4.056 ± 0.852
6.24AlaLys: 6.24 ± 1.44
6.24AlaLeu: 6.24 ± 2.03
1.872AlaMet: 1.872 ± 1.256
3.432AlaAsn: 3.432 ± 0.689
3.12AlaPro: 3.12 ± 0.694
1.872AlaGln: 1.872 ± 0.341
2.496AlaArg: 2.496 ± 0.948
3.744AlaSer: 3.744 ± 0.543
6.24AlaThr: 6.24 ± 1.797
4.992AlaVal: 4.992 ± 1.054
0.624AlaTrp: 0.624 ± 0.381
2.808AlaTyr: 2.808 ± 0.837
0.0AlaXaa: 0.0 ± 0.0
Cys
0.624CysAla: 0.624 ± 0.625
0.0CysCys: 0.0 ± 0.0
1.248CysAsp: 1.248 ± 1.329
0.624CysGlu: 0.624 ± 0.664
1.248CysPhe: 1.248 ± 0.762
0.624CysGly: 0.624 ± 0.325
0.936CysHis: 0.936 ± 0.628
0.0CysIle: 0.0 ± 0.0
0.624CysLys: 0.624 ± 0.325
1.248CysLeu: 1.248 ± 0.431
0.0CysMet: 0.0 ± 0.0
0.312CysAsn: 0.312 ± 0.162
0.624CysPro: 0.624 ± 0.664
0.936CysGln: 0.936 ± 0.628
0.624CysArg: 0.624 ± 1.471
2.184CysSer: 2.184 ± 0.597
1.248CysThr: 1.248 ± 0.649
0.312CysVal: 0.312 ± 0.162
0.312CysTrp: 0.312 ± 0.162
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.368AspAla: 4.368 ± 1.356
1.248AspCys: 1.248 ± 1.329
3.744AspAsp: 3.744 ± 0.722
4.368AspGlu: 4.368 ± 0.744
4.992AspPhe: 4.992 ± 2.221
2.496AspGly: 2.496 ± 1.103
0.624AspHis: 0.624 ± 0.325
4.68AspIle: 4.68 ± 1.783
1.872AspLys: 1.872 ± 1.197
4.368AspLeu: 4.368 ± 1.103
1.248AspMet: 1.248 ± 0.649
1.56AspAsn: 1.56 ± 0.534
3.12AspPro: 3.12 ± 0.678
1.872AspGln: 1.872 ± 0.341
2.808AspArg: 2.808 ± 0.837
4.056AspSer: 4.056 ± 0.415
2.184AspThr: 2.184 ± 0.746
4.056AspVal: 4.056 ± 1.459
0.0AspTrp: 0.0 ± 0.0
2.808AspTyr: 2.808 ± 0.672
0.0AspXaa: 0.0 ± 0.0
Glu
5.304GluAla: 5.304 ± 1.597
0.0GluCys: 0.0 ± 0.0
2.184GluAsp: 2.184 ± 0.646
4.056GluGlu: 4.056 ± 0.397
3.432GluPhe: 3.432 ± 2.093
4.056GluGly: 4.056 ± 1.323
1.56GluHis: 1.56 ± 0.677
6.864GluIle: 6.864 ± 1.191
3.744GluLys: 3.744 ± 1.271
5.928GluLeu: 5.928 ± 0.743
0.936GluMet: 0.936 ± 0.323
4.992GluAsn: 4.992 ± 1.315
1.872GluPro: 1.872 ± 1.256
2.184GluGln: 2.184 ± 0.769
1.248GluArg: 1.248 ± 0.649
2.184GluSer: 2.184 ± 0.413
3.432GluThr: 3.432 ± 1.057
3.744GluVal: 3.744 ± 1.29
0.312GluTrp: 0.312 ± 0.162
2.184GluTyr: 2.184 ± 0.413
0.0GluXaa: 0.0 ± 0.0
Phe
2.496PheAla: 2.496 ± 0.822
2.184PheCys: 2.184 ± 0.646
3.12PheAsp: 3.12 ± 0.87
3.432PheGlu: 3.432 ± 0.794
2.496PhePhe: 2.496 ± 1.835
4.056PheGly: 4.056 ± 1.432
1.872PheHis: 1.872 ± 0.647
1.248PheIle: 1.248 ± 0.732
4.368PheLys: 4.368 ± 1.82
4.992PheLeu: 4.992 ± 1.036
1.248PheMet: 1.248 ± 0.885
2.496PheAsn: 2.496 ± 0.948
3.432PhePro: 3.432 ± 1.275
1.56PheGln: 1.56 ± 1.968
2.496PheArg: 2.496 ± 0.858
3.744PheSer: 3.744 ± 2.202
4.368PheThr: 4.368 ± 1.086
2.184PheVal: 2.184 ± 0.801
1.248PheTrp: 1.248 ± 0.632
2.496PheTyr: 2.496 ± 0.543
0.0PheXaa: 0.0 ± 0.0
Gly
4.68GlyAla: 4.68 ± 0.933
0.312GlyCys: 0.312 ± 0.162
2.496GlyAsp: 2.496 ± 0.842
2.808GlyGlu: 2.808 ± 1.118
3.12GlyPhe: 3.12 ± 0.593
3.12GlyGly: 3.12 ± 1.102
1.248GlyHis: 1.248 ± 0.649
3.432GlyIle: 3.432 ± 0.819
4.056GlyLys: 4.056 ± 0.853
4.68GlyLeu: 4.68 ± 1.282
1.248GlyMet: 1.248 ± 0.431
1.56GlyAsn: 1.56 ± 0.593
1.56GlyPro: 1.56 ± 0.811
2.184GlyGln: 2.184 ± 0.605
2.184GlyArg: 2.184 ± 0.413
5.616GlySer: 5.616 ± 1.28
4.368GlyThr: 4.368 ± 1.818
1.872GlyVal: 1.872 ± 0.974
0.0GlyTrp: 0.0 ± 0.0
1.56GlyTyr: 1.56 ± 0.677
0.0GlyXaa: 0.0 ± 0.0
His
1.56HisAla: 1.56 ± 0.811
1.248HisCys: 1.248 ± 0.431
1.248HisAsp: 1.248 ± 0.372
1.248HisGlu: 1.248 ± 0.408
2.496HisPhe: 2.496 ± 0.948
1.56HisGly: 1.56 ± 0.811
0.936HisHis: 0.936 ± 0.323
0.0HisIle: 0.0 ± 0.0
2.184HisLys: 2.184 ± 0.856
1.248HisLeu: 1.248 ± 0.372
0.312HisMet: 0.312 ± 0.162
1.56HisAsn: 1.56 ± 0.811
0.624HisPro: 0.624 ± 0.325
0.624HisGln: 0.624 ± 0.325
1.248HisArg: 1.248 ± 0.632
1.872HisSer: 1.872 ± 1.053
1.872HisThr: 1.872 ± 0.641
0.624HisVal: 0.624 ± 0.325
0.0HisTrp: 0.0 ± 0.0
0.312HisTyr: 0.312 ± 0.162
0.0HisXaa: 0.0 ± 0.0
Ile
5.928IleAla: 5.928 ± 1.727
1.248IleCys: 1.248 ± 0.706
4.992IleAsp: 4.992 ± 1.391
4.368IleGlu: 4.368 ± 1.222
1.56IlePhe: 1.56 ± 0.723
4.68IleGly: 4.68 ± 0.933
1.248IleHis: 1.248 ± 0.908
4.992IleIle: 4.992 ± 2.832
4.68IleLys: 4.68 ± 0.963
4.056IleLeu: 4.056 ± 0.73
1.248IleMet: 1.248 ± 0.649
3.432IleAsn: 3.432 ± 1.411
4.992IlePro: 4.992 ± 1.217
3.432IleGln: 3.432 ± 2.364
2.496IleArg: 2.496 ± 0.542
4.992IleSer: 4.992 ± 1.024
5.928IleThr: 5.928 ± 0.774
3.12IleVal: 3.12 ± 1.345
0.624IleTrp: 0.624 ± 0.351
3.432IleTyr: 3.432 ± 1.711
0.0IleXaa: 0.0 ± 0.0
Lys
2.808LysAla: 2.808 ± 0.525
1.872LysCys: 1.872 ± 0.755
5.928LysAsp: 5.928 ± 1.069
4.68LysGlu: 4.68 ± 1.332
4.056LysPhe: 4.056 ± 1.143
4.056LysGly: 4.056 ± 2.11
0.936LysHis: 0.936 ± 0.487
5.928LysIle: 5.928 ± 1.344
2.184LysLys: 2.184 ± 0.646
5.616LysLeu: 5.616 ± 1.558
1.872LysMet: 1.872 ± 0.798
4.056LysAsn: 4.056 ± 1.738
3.12LysPro: 3.12 ± 0.694
1.872LysGln: 1.872 ± 0.647
3.744LysArg: 3.744 ± 1.129
2.496LysSer: 2.496 ± 0.974
6.24LysThr: 6.24 ± 1.225
5.304LysVal: 5.304 ± 2.547
1.872LysTrp: 1.872 ± 0.604
1.872LysTyr: 1.872 ± 0.647
0.0LysXaa: 0.0 ± 0.0
Leu
5.928LeuAla: 5.928 ± 0.982
0.936LeuCys: 0.936 ± 1.392
4.68LeuAsp: 4.68 ± 1.23
3.12LeuGlu: 3.12 ± 0.604
4.992LeuPhe: 4.992 ± 0.73
3.744LeuGly: 3.744 ± 0.725
1.872LeuHis: 1.872 ± 0.974
5.928LeuIle: 5.928 ± 1.34
6.24LeuLys: 6.24 ± 0.796
5.616LeuLeu: 5.616 ± 2.88
1.872LeuMet: 1.872 ± 0.341
6.24LeuAsn: 6.24 ± 2.011
5.304LeuPro: 5.304 ± 1.826
3.432LeuGln: 3.432 ± 1.074
4.368LeuArg: 4.368 ± 0.826
8.112LeuSer: 8.112 ± 1.657
4.992LeuThr: 4.992 ± 2.578
2.808LeuVal: 2.808 ± 1.757
0.624LeuTrp: 0.624 ± 0.325
0.624LeuTyr: 0.624 ± 0.351
0.0LeuXaa: 0.0 ± 0.0
Met
1.872MetAla: 1.872 ± 0.974
0.0MetCys: 0.0 ± 0.0
0.624MetAsp: 0.624 ± 0.325
1.248MetGlu: 1.248 ± 1.329
1.56MetPhe: 1.56 ± 0.475
1.56MetGly: 1.56 ± 0.811
0.312MetHis: 0.312 ± 0.162
1.248MetIle: 1.248 ± 1.035
0.936MetLys: 0.936 ± 0.487
1.56MetLeu: 1.56 ± 0.677
0.624MetMet: 0.624 ± 0.851
1.248MetAsn: 1.248 ± 0.895
1.56MetPro: 1.56 ± 0.655
0.624MetGln: 0.624 ± 0.653
0.936MetArg: 0.936 ± 0.52
2.184MetSer: 2.184 ± 0.856
1.248MetThr: 1.248 ± 0.702
1.56MetVal: 1.56 ± 0.475
0.0MetTrp: 0.0 ± 0.0
0.936MetTyr: 0.936 ± 0.487
0.0MetXaa: 0.0 ± 0.0
Asn
4.368AsnAla: 4.368 ± 0.488
0.312AsnCys: 0.312 ± 0.162
3.12AsnAsp: 3.12 ± 0.678
2.496AsnGlu: 2.496 ± 1.768
2.496AsnPhe: 2.496 ± 0.723
3.12AsnGly: 3.12 ± 1.073
1.56AsnHis: 1.56 ± 0.475
5.928AsnIle: 5.928 ± 1.772
4.056AsnLys: 4.056 ± 0.666
4.992AsnLeu: 4.992 ± 1.21
0.936AsnMet: 0.936 ± 0.331
3.744AsnAsn: 3.744 ± 0.919
0.624AsnPro: 0.624 ± 0.381
3.432AsnGln: 3.432 ± 2.449
1.872AsnArg: 1.872 ± 1.197
3.432AsnSer: 3.432 ± 2.006
4.68AsnThr: 4.68 ± 0.752
3.744AsnVal: 3.744 ± 0.888
0.936AsnTrp: 0.936 ± 0.323
1.56AsnTyr: 1.56 ± 0.811
0.0AsnXaa: 0.0 ± 0.0
Pro
2.808ProAla: 2.808 ± 0.661
0.936ProCys: 0.936 ± 0.487
2.808ProAsp: 2.808 ± 0.789
2.496ProGlu: 2.496 ± 0.543
3.744ProPhe: 3.744 ± 1.223
2.496ProGly: 2.496 ± 1.103
0.624ProHis: 0.624 ± 0.325
3.744ProIle: 3.744 ± 1.203
3.432ProLys: 3.432 ± 1.074
5.304ProLeu: 5.304 ± 1.178
0.312ProMet: 0.312 ± 0.162
2.184ProAsn: 2.184 ± 0.678
1.872ProPro: 1.872 ± 0.659
0.936ProGln: 0.936 ± 0.373
1.872ProArg: 1.872 ± 0.707
1.56ProSer: 1.56 ± 0.648
2.496ProThr: 2.496 ± 1.265
3.744ProVal: 3.744 ± 1.686
0.0ProTrp: 0.0 ± 0.0
1.248ProTyr: 1.248 ± 0.616
0.0ProXaa: 0.0 ± 0.0
Gln
3.432GlnAla: 3.432 ± 0.693
0.0GlnCys: 0.0 ± 0.0
1.248GlnAsp: 1.248 ± 0.895
0.936GlnGlu: 0.936 ± 0.886
0.624GlnPhe: 0.624 ± 0.351
1.872GlnGly: 1.872 ± 0.659
1.56GlnHis: 1.56 ± 0.534
3.12GlnIle: 3.12 ± 2.209
2.496GlnLys: 2.496 ± 0.705
1.56GlnLeu: 1.56 ± 0.475
1.872GlnMet: 1.872 ± 0.667
1.872GlnAsn: 1.872 ± 0.572
1.872GlnPro: 1.872 ± 0.707
1.248GlnGln: 1.248 ± 0.649
2.808GlnArg: 2.808 ± 1.734
1.872GlnSer: 1.872 ± 0.604
3.432GlnThr: 3.432 ± 2.603
2.496GlnVal: 2.496 ± 1.464
0.0GlnTrp: 0.0 ± 0.0
1.56GlnTyr: 1.56 ± 0.763
0.0GlnXaa: 0.0 ± 0.0
Arg
2.496ArgAla: 2.496 ± 0.895
0.0ArgCys: 0.0 ± 0.0
1.872ArgAsp: 1.872 ± 0.647
2.496ArgGlu: 2.496 ± 0.695
2.496ArgPhe: 2.496 ± 0.527
0.936ArgGly: 0.936 ± 1.033
1.248ArgHis: 1.248 ± 0.649
4.992ArgIle: 4.992 ± 2.036
4.992ArgLys: 4.992 ± 1.391
3.744ArgLeu: 3.744 ± 0.884
1.248ArgMet: 1.248 ± 0.632
3.432ArgAsn: 3.432 ± 1.585
0.936ArgPro: 0.936 ± 1.019
2.184ArgGln: 2.184 ± 0.645
1.872ArgArg: 1.872 ± 0.755
1.872ArgSer: 1.872 ± 0.707
1.872ArgThr: 1.872 ± 0.341
4.056ArgVal: 4.056 ± 0.639
0.936ArgTrp: 0.936 ± 0.373
1.56ArgTyr: 1.56 ± 0.648
0.0ArgXaa: 0.0 ± 0.0
Ser
4.368SerAla: 4.368 ± 1.356
0.312SerCys: 0.312 ± 0.162
3.12SerAsp: 3.12 ± 1.117
4.992SerGlu: 4.992 ± 1.271
2.496SerPhe: 2.496 ± 1.446
3.12SerGly: 3.12 ± 0.847
0.936SerHis: 0.936 ± 0.323
3.432SerIle: 3.432 ± 2.048
7.176SerLys: 7.176 ± 1.074
5.304SerLeu: 5.304 ± 1.336
1.248SerMet: 1.248 ± 0.649
4.056SerAsn: 4.056 ± 0.874
2.808SerPro: 2.808 ± 0.753
0.624SerGln: 0.624 ± 0.325
3.744SerArg: 3.744 ± 0.676
5.616SerSer: 5.616 ± 2.211
6.552SerThr: 6.552 ± 1.848
4.056SerVal: 4.056 ± 1.366
0.624SerTrp: 0.624 ± 0.325
1.872SerTyr: 1.872 ± 1.612
0.0SerXaa: 0.0 ± 0.0
Thr
3.432ThrAla: 3.432 ± 1.28
0.624ThrCys: 0.624 ± 0.664
4.68ThrAsp: 4.68 ± 1.623
6.864ThrGlu: 6.864 ± 1.805
6.24ThrPhe: 6.24 ± 1.184
3.432ThrGly: 3.432 ± 1.76
1.872ThrHis: 1.872 ± 0.974
6.24ThrIle: 6.24 ± 0.858
5.616ThrLys: 5.616 ± 0.593
4.368ThrLeu: 4.368 ± 1.986
1.872ThrMet: 1.872 ± 0.636
4.992ThrAsn: 4.992 ± 1.006
3.12ThrPro: 3.12 ± 0.694
2.184ThrGln: 2.184 ± 1.34
1.872ThrArg: 1.872 ± 0.341
5.928ThrSer: 5.928 ± 1.34
4.368ThrThr: 4.368 ± 2.33
2.496ThrVal: 2.496 ± 0.995
1.248ThrTrp: 1.248 ± 0.649
1.56ThrTyr: 1.56 ± 0.673
0.0ThrXaa: 0.0 ± 0.0
Val
5.304ValAla: 5.304 ± 1.45
0.312ValCys: 0.312 ± 0.162
3.432ValAsp: 3.432 ± 1.361
3.432ValGlu: 3.432 ± 0.902
1.872ValPhe: 1.872 ± 0.755
1.248ValGly: 1.248 ± 0.632
2.184ValHis: 2.184 ± 0.413
3.432ValIle: 3.432 ± 1.057
1.872ValLys: 1.872 ± 0.845
4.056ValLeu: 4.056 ± 0.726
1.248ValMet: 1.248 ± 0.472
4.68ValAsn: 4.68 ± 1.08
3.12ValPro: 3.12 ± 0.949
2.184ValGln: 2.184 ± 0.789
4.056ValArg: 4.056 ± 2.898
3.12ValSer: 3.12 ± 0.896
4.68ValThr: 4.68 ± 0.887
4.056ValVal: 4.056 ± 0.931
0.312ValTrp: 0.312 ± 0.441
2.808ValTyr: 2.808 ± 0.832
0.0ValXaa: 0.0 ± 0.0
Trp
1.248TrpAla: 1.248 ± 0.649
0.312TrpCys: 0.312 ± 0.162
0.312TrpAsp: 0.312 ± 0.452
0.312TrpGlu: 0.312 ± 0.736
0.0TrpPhe: 0.0 ± 0.0
0.312TrpGly: 0.312 ± 0.162
0.0TrpHis: 0.0 ± 0.0
0.936TrpIle: 0.936 ± 0.373
0.936TrpLys: 0.936 ± 0.487
0.936TrpLeu: 0.936 ± 1.323
0.0TrpMet: 0.0 ± 0.0
0.312TrpAsn: 0.312 ± 0.162
0.624TrpPro: 0.624 ± 0.325
1.248TrpGln: 1.248 ± 0.372
0.312TrpArg: 0.312 ± 0.162
0.0TrpSer: 0.0 ± 0.0
0.936TrpThr: 0.936 ± 0.487
0.936TrpVal: 0.936 ± 0.487
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.184TyrAla: 2.184 ± 0.647
0.312TyrCys: 0.312 ± 0.452
1.872TyrAsp: 1.872 ± 0.647
2.184TyrGlu: 2.184 ± 0.789
1.872TyrPhe: 1.872 ± 0.636
2.496TyrGly: 2.496 ± 0.739
0.0TyrHis: 0.0 ± 0.0
1.248TyrIle: 1.248 ± 0.431
2.808TyrLys: 2.808 ± 0.776
5.616TyrLeu: 5.616 ± 1.577
0.312TyrMet: 0.312 ± 0.441
1.248TyrAsn: 1.248 ± 0.792
0.312TyrPro: 0.312 ± 0.162
1.248TyrGln: 1.248 ± 0.655
2.184TyrArg: 2.184 ± 1.0
1.872TyrSer: 1.872 ± 0.701
1.872TyrThr: 1.872 ± 0.604
1.56TyrVal: 1.56 ± 0.655
0.0TyrTrp: 0.0 ± 0.0
1.248TyrTyr: 1.248 ± 0.885
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3206 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski