Amino acid dipepetide frequency for Actinocorallia herbida

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.521AlaAla: 22.521 ± 0.159	1.101AlaCys: 1.101 ± 0.021	8.8AlaAsp: 8.8 ± 0.057	9.79AlaGlu: 9.79 ± 0.083	4.069AlaPhe: 4.069 ± 0.041	12.722AlaGly: 12.722 ± 0.07	2.95AlaHis: 2.95 ± 0.032	4.149AlaIle: 4.149 ± 0.038	2.894AlaLys: 2.894 ± 0.042	15.719AlaLeu: 15.719 ± 0.103	2.503AlaMet: 2.503 ± 0.029	1.915AlaAsn: 1.915 ± 0.029	7.278AlaPro: 7.278 ± 0.071	3.429AlaGln: 3.429 ± 0.037	10.59AlaArg: 10.59 ± 0.079	6.068AlaSer: 6.068 ± 0.055	6.528AlaThr: 6.528 ± 0.055	12.302AlaVal: 12.302 ± 0.082	1.984AlaTrp: 1.984 ± 0.028	2.658AlaTyr: 2.658 ± 0.03	0.0AlaXaa: 0.0 ± 0.0
Cys	1.171CysAla: 1.171 ± 0.024	0.093CysCys: 0.093 ± 0.006	0.48CysAsp: 0.48 ± 0.014	0.366CysGlu: 0.366 ± 0.011	0.218CysPhe: 0.218 ± 0.008	0.94CysGly: 0.94 ± 0.019	0.192CysHis: 0.192 ± 0.008	0.14CysIle: 0.14 ± 0.007	0.121CysLys: 0.121 ± 0.007	0.758CysLeu: 0.758 ± 0.015	0.109CysMet: 0.109 ± 0.006	0.105CysAsn: 0.105 ± 0.006	0.499CysPro: 0.499 ± 0.016	0.156CysGln: 0.156 ± 0.007	0.577CysArg: 0.577 ± 0.016	0.39CysSer: 0.39 ± 0.012	0.455CysThr: 0.455 ± 0.014	0.644CysVal: 0.644 ± 0.017	0.113CysTrp: 0.113 ± 0.006	0.144CysTyr: 0.144 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	7.725AspAla: 7.725 ± 0.063	0.382AspCys: 0.382 ± 0.012	3.501AspAsp: 3.501 ± 0.036	3.593AspGlu: 3.593 ± 0.038	1.723AspPhe: 1.723 ± 0.029	6.425AspGly: 6.425 ± 0.05	1.423AspHis: 1.423 ± 0.024	1.721AspIle: 1.721 ± 0.026	1.048AspLys: 1.048 ± 0.025	7.427AspLeu: 7.427 ± 0.055	0.763AspMet: 0.763 ± 0.015	0.764AspAsn: 0.764 ± 0.018	5.053AspPro: 5.053 ± 0.052	1.355AspGln: 1.355 ± 0.025	4.835AspArg: 4.835 ± 0.042	2.038AspSer: 2.038 ± 0.026	2.698AspThr: 2.698 ± 0.035	4.813AspVal: 4.813 ± 0.042	0.911AspTrp: 0.911 ± 0.019	1.122AspTyr: 1.122 ± 0.025	0.0AspXaa: 0.0 ± 0.0
Glu	7.762GluAla: 7.762 ± 0.067	0.35GluCys: 0.35 ± 0.012	2.905GluAsp: 2.905 ± 0.033	3.491GluGlu: 3.491 ± 0.045	1.682GluPhe: 1.682 ± 0.026	4.719GluGly: 4.719 ± 0.044	1.498GluHis: 1.498 ± 0.023	2.681GluIle: 2.681 ± 0.032	1.303GluLys: 1.303 ± 0.025	6.49GluLeu: 6.49 ± 0.059	0.895GluMet: 0.895 ± 0.019	0.986GluAsn: 0.986 ± 0.018	3.436GluPro: 3.436 ± 0.041	1.798GluGln: 1.798 ± 0.025	5.282GluArg: 5.282 ± 0.046	2.526GluSer: 2.526 ± 0.032	3.158GluThr: 3.158 ± 0.031	4.695GluVal: 4.695 ± 0.051	0.747GluTrp: 0.747 ± 0.017	1.061GluTyr: 1.061 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.357PheAla: 4.357 ± 0.041	0.292PheCys: 0.292 ± 0.01	2.086PheAsp: 2.086 ± 0.028	1.448PheGlu: 1.448 ± 0.024	0.917PhePhe: 0.917 ± 0.02	3.378PheGly: 3.378 ± 0.036	0.666PheHis: 0.666 ± 0.015	0.774PheIle: 0.774 ± 0.019	0.547PheLys: 0.547 ± 0.015	2.899PheLeu: 2.899 ± 0.037	0.422PheMet: 0.422 ± 0.013	0.576PheAsn: 0.576 ± 0.015	1.581PhePro: 1.581 ± 0.025	0.747PheGln: 0.747 ± 0.016	1.875PheArg: 1.875 ± 0.028	1.482PheSer: 1.482 ± 0.023	2.256PheThr: 2.256 ± 0.028	2.333PheVal: 2.333 ± 0.031	0.452PheTrp: 0.452 ± 0.011	0.618PheTyr: 0.618 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	11.395GlyAla: 11.395 ± 0.07	0.824GlyCys: 0.824 ± 0.017	5.183GlyAsp: 5.183 ± 0.046	5.173GlyGlu: 5.173 ± 0.048	3.17GlyPhe: 3.17 ± 0.038	8.959GlyGly: 8.959 ± 0.076	2.216GlyHis: 2.216 ± 0.034	3.49GlyIle: 3.49 ± 0.039	2.334GlyLys: 2.334 ± 0.036	10.408GlyLeu: 10.408 ± 0.071	1.984GlyMet: 1.984 ± 0.028	1.51GlyAsn: 1.51 ± 0.025	5.482GlyPro: 5.482 ± 0.058	2.407GlyGln: 2.407 ± 0.04	7.85GlyArg: 7.85 ± 0.053	4.868GlySer: 4.868 ± 0.046	5.941GlyThr: 5.941 ± 0.053	7.881GlyVal: 7.881 ± 0.058	1.738GlyTrp: 1.738 ± 0.027	2.247GlyTyr: 2.247 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	2.657HisAla: 2.657 ± 0.034	0.196HisCys: 0.196 ± 0.009	1.315HisAsp: 1.315 ± 0.021	1.163HisGlu: 1.163 ± 0.019	0.624HisPhe: 0.624 ± 0.017	2.379HisGly: 2.379 ± 0.035	0.679HisHis: 0.679 ± 0.019	0.623HisIle: 0.623 ± 0.014	0.312HisLys: 0.312 ± 0.01	2.58HisLeu: 2.58 ± 0.032	0.304HisMet: 0.304 ± 0.012	0.317HisAsn: 0.317 ± 0.012	1.773HisPro: 1.773 ± 0.029	0.507HisGln: 0.507 ± 0.013	2.03HisArg: 2.03 ± 0.028	0.893HisSer: 0.893 ± 0.019	1.183HisThr: 1.183 ± 0.023	1.641HisVal: 1.641 ± 0.023	0.351HisTrp: 0.351 ± 0.011	0.469HisTyr: 0.469 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.294IleAla: 5.294 ± 0.051	0.304IleCys: 0.304 ± 0.01	2.318IleAsp: 2.318 ± 0.026	2.171IleGlu: 2.171 ± 0.033	0.834IlePhe: 0.834 ± 0.02	3.731IleGly: 3.731 ± 0.043	0.603IleHis: 0.603 ± 0.016	1.125IleIle: 1.125 ± 0.022	0.755IleLys: 0.755 ± 0.018	2.852IleLeu: 2.852 ± 0.039	0.522IleMet: 0.522 ± 0.016	0.667IleAsn: 0.667 ± 0.015	1.938IlePro: 1.938 ± 0.025	0.717IleGln: 0.717 ± 0.015	2.319IleArg: 2.319 ± 0.027	1.799IleSer: 1.799 ± 0.031	2.421IleThr: 2.421 ± 0.03	3.131IleVal: 3.131 ± 0.037	0.392IleTrp: 0.392 ± 0.013	0.542IleTyr: 0.542 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	2.982LysAla: 2.982 ± 0.04	0.117LysCys: 0.117 ± 0.007	1.206LysAsp: 1.206 ± 0.022	1.122LysGlu: 1.122 ± 0.024	0.46LysPhe: 0.46 ± 0.015	1.807LysGly: 1.807 ± 0.031	0.398LysHis: 0.398 ± 0.011	1.029LysIle: 1.029 ± 0.021	0.71LysLys: 0.71 ± 0.02	1.771LysLeu: 1.771 ± 0.027	0.359LysMet: 0.359 ± 0.011	0.485LysAsn: 0.485 ± 0.015	1.27LysPro: 1.27 ± 0.029	0.509LysGln: 0.509 ± 0.014	1.396LysArg: 1.396 ± 0.025	1.074LysSer: 1.074 ± 0.021	1.334LysThr: 1.334 ± 0.023	1.969LysVal: 1.969 ± 0.031	0.272LysTrp: 0.272 ± 0.01	0.414LysTyr: 0.414 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	16.353LeuAla: 16.353 ± 0.094	0.848LeuCys: 0.848 ± 0.019	6.961LeuAsp: 6.961 ± 0.058	5.08LeuGlu: 5.08 ± 0.043	2.837LeuPhe: 2.837 ± 0.033	9.865LeuGly: 9.865 ± 0.071	2.306LeuHis: 2.306 ± 0.035	3.617LeuIle: 3.617 ± 0.044	2.04LeuLys: 2.04 ± 0.034	11.586LeuLeu: 11.586 ± 0.087	1.633LeuMet: 1.633 ± 0.026	1.727LeuAsn: 1.727 ± 0.025	6.793LeuPro: 6.793 ± 0.056	2.023LeuGln: 2.023 ± 0.029	8.962LeuArg: 8.962 ± 0.07	5.431LeuSer: 5.431 ± 0.049	7.136LeuThr: 7.136 ± 0.06	8.962LeuVal: 8.962 ± 0.064	1.383LeuTrp: 1.383 ± 0.024	1.888LeuTyr: 1.888 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	2.259MetAla: 2.259 ± 0.029	0.125MetCys: 0.125 ± 0.008	0.853MetAsp: 0.853 ± 0.017	0.746MetGlu: 0.746 ± 0.017	0.499MetPhe: 0.499 ± 0.016	1.322MetGly: 1.322 ± 0.023	0.328MetHis: 0.328 ± 0.012	0.764MetIle: 0.764 ± 0.022	0.423MetLys: 0.423 ± 0.013	1.711MetLeu: 1.711 ± 0.021	0.304MetMet: 0.304 ± 0.011	0.435MetAsn: 0.435 ± 0.013	1.08MetPro: 1.08 ± 0.021	0.377MetGln: 0.377 ± 0.011	1.491MetArg: 1.491 ± 0.026	1.326MetSer: 1.326 ± 0.02	1.507MetThr: 1.507 ± 0.021	1.217MetVal: 1.217 ± 0.023	0.19MetTrp: 0.19 ± 0.007	0.271MetTyr: 0.271 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.252AsnAla: 2.252 ± 0.033	0.152AsnCys: 0.152 ± 0.008	0.864AsnAsp: 0.864 ± 0.017	0.762AsnGlu: 0.762 ± 0.017	0.444AsnPhe: 0.444 ± 0.013	1.765AsnGly: 1.765 ± 0.029	0.339AsnHis: 0.339 ± 0.011	0.625AsnIle: 0.625 ± 0.018	0.339AsnLys: 0.339 ± 0.012	1.7AsnLeu: 1.7 ± 0.025	0.251AsnMet: 0.251 ± 0.009	0.323AsnAsn: 0.323 ± 0.012	1.323AsnPro: 1.323 ± 0.018	0.401AsnGln: 0.401 ± 0.013	1.177AsnArg: 1.177 ± 0.023	0.714AsnSer: 0.714 ± 0.017	0.985AsnThr: 0.985 ± 0.018	1.361AsnVal: 1.361 ± 0.025	0.245AsnTrp: 0.245 ± 0.009	0.38AsnTyr: 0.38 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	8.682ProAla: 8.682 ± 0.083	0.336ProCys: 0.336 ± 0.012	4.66ProAsp: 4.66 ± 0.049	4.627ProGlu: 4.627 ± 0.046	1.765ProPhe: 1.765 ± 0.023	6.801ProGly: 6.801 ± 0.067	1.321ProHis: 1.321 ± 0.022	1.652ProIle: 1.652 ± 0.026	1.232ProLys: 1.232 ± 0.021	5.52ProLeu: 5.52 ± 0.046	1.086ProMet: 1.086 ± 0.022	0.918ProAsn: 0.918 ± 0.018	3.666ProPro: 3.666 ± 0.056	1.472ProGln: 1.472 ± 0.028	4.004ProArg: 4.004 ± 0.042	3.473ProSer: 3.473 ± 0.043	3.046ProThr: 3.046 ± 0.042	5.508ProVal: 5.508 ± 0.043	0.984ProTrp: 0.984 ± 0.019	1.371ProTyr: 1.371 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.305GlnAla: 3.305 ± 0.041	0.157GlnCys: 0.157 ± 0.008	1.244GlnAsp: 1.244 ± 0.023	1.233GlnGlu: 1.233 ± 0.02	0.65GlnPhe: 0.65 ± 0.016	2.176GlnGly: 2.176 ± 0.029	0.481GlnHis: 0.481 ± 0.013	1.164GlnIle: 1.164 ± 0.022	0.518GlnLys: 0.518 ± 0.014	2.266GlnLeu: 2.266 ± 0.031	0.437GlnMet: 0.437 ± 0.012	0.48GlnAsn: 0.48 ± 0.014	1.346GlnPro: 1.346 ± 0.029	0.859GlnGln: 0.859 ± 0.03	2.076GlnArg: 2.076 ± 0.029	1.066GlnSer: 1.066 ± 0.02	1.326GlnThr: 1.326 ± 0.021	2.139GlnVal: 2.139 ± 0.027	0.392GlnTrp: 0.392 ± 0.012	0.471GlnTyr: 0.471 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	10.411ArgAla: 10.411 ± 0.08	0.554ArgCys: 0.554 ± 0.015	4.438ArgAsp: 4.438 ± 0.042	4.722ArgGlu: 4.722 ± 0.05	2.539ArgPhe: 2.539 ± 0.035	5.734ArgGly: 5.734 ± 0.051	1.974ArgHis: 1.974 ± 0.028	3.313ArgIle: 3.313 ± 0.034	1.614ArgLys: 1.614 ± 0.027	9.059ArgLeu: 9.059 ± 0.071	1.78ArgMet: 1.78 ± 0.027	1.233ArgAsn: 1.233 ± 0.02	5.019ArgPro: 5.019 ± 0.051	1.937ArgGln: 1.937 ± 0.028	7.442ArgArg: 7.442 ± 0.061	3.704ArgSer: 3.704 ± 0.041	4.902ArgThr: 4.902 ± 0.045	6.101ArgVal: 6.101 ± 0.047	1.355ArgTrp: 1.355 ± 0.023	1.783ArgTyr: 1.783 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	6.685SerAla: 6.685 ± 0.052	0.382SerCys: 0.382 ± 0.012	2.506SerAsp: 2.506 ± 0.028	2.208SerGlu: 2.208 ± 0.027	1.672SerPhe: 1.672 ± 0.025	5.867SerGly: 5.867 ± 0.05	0.908SerHis: 0.908 ± 0.017	1.523SerIle: 1.523 ± 0.026	0.879SerLys: 0.879 ± 0.02	4.968SerLeu: 4.968 ± 0.046	1.007SerMet: 1.007 ± 0.022	0.71SerAsn: 0.71 ± 0.017	3.287SerPro: 3.287 ± 0.042	1.012SerGln: 1.012 ± 0.02	3.547SerArg: 3.547 ± 0.037	2.575SerSer: 2.575 ± 0.038	2.603SerThr: 2.603 ± 0.032	4.122SerVal: 4.122 ± 0.045	0.9SerTrp: 0.9 ± 0.021	1.137SerTyr: 1.137 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	8.508ThrAla: 8.508 ± 0.061	0.415ThrCys: 0.415 ± 0.011	3.335ThrAsp: 3.335 ± 0.034	3.182ThrGlu: 3.182 ± 0.031	1.727ThrPhe: 1.727 ± 0.024	6.556ThrGly: 6.556 ± 0.056	1.056ThrHis: 1.056 ± 0.021	1.856ThrIle: 1.856 ± 0.027	1.077ThrLys: 1.077 ± 0.021	5.738ThrLeu: 5.738 ± 0.044	0.94ThrMet: 0.94 ± 0.021	0.889ThrAsn: 0.889 ± 0.02	3.942ThrPro: 3.942 ± 0.047	1.072ThrGln: 1.072 ± 0.02	4.056ThrArg: 4.056 ± 0.047	2.969ThrSer: 2.969 ± 0.033	3.494ThrThr: 3.494 ± 0.052	5.652ThrVal: 5.652 ± 0.053	0.935ThrTrp: 0.935 ± 0.018	1.211ThrTyr: 1.211 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	11.27ValAla: 11.27 ± 0.071	0.708ValCys: 0.708 ± 0.017	4.539ValAsp: 4.539 ± 0.045	4.724ValGlu: 4.724 ± 0.045	2.685ValPhe: 2.685 ± 0.033	6.694ValGly: 6.694 ± 0.06	1.867ValHis: 1.867 ± 0.025	3.082ValIle: 3.082 ± 0.037	1.759ValLys: 1.759 ± 0.03	10.009ValLeu: 10.009 ± 0.064	1.403ValMet: 1.403 ± 0.026	1.621ValAsn: 1.621 ± 0.028	5.403ValPro: 5.403 ± 0.052	1.968ValGln: 1.968 ± 0.029	6.933ValArg: 6.933 ± 0.059	4.287ValSer: 4.287 ± 0.046	5.319ValThr: 5.319 ± 0.051	7.779ValVal: 7.779 ± 0.067	1.147ValTrp: 1.147 ± 0.02	1.526ValTyr: 1.526 ± 0.025	0.0ValXaa: 0.0 ± 0.0
Trp	1.753TrpAla: 1.753 ± 0.031	0.153TrpCys: 0.153 ± 0.007	0.793TrpAsp: 0.793 ± 0.019	0.764TrpGlu: 0.764 ± 0.018	0.515TrpPhe: 0.515 ± 0.014	1.064TrpGly: 1.064 ± 0.021	0.402TrpHis: 0.402 ± 0.011	0.627TrpIle: 0.627 ± 0.015	0.391TrpLys: 0.391 ± 0.013	1.705TrpLeu: 1.705 ± 0.024	0.288TrpMet: 0.288 ± 0.01	0.395TrpAsn: 0.395 ± 0.012	0.842TrpPro: 0.842 ± 0.018	0.496TrpGln: 0.496 ± 0.014	1.396TrpArg: 1.396 ± 0.024	0.878TrpSer: 0.878 ± 0.019	1.122TrpThr: 1.122 ± 0.02	0.921TrpVal: 0.921 ± 0.017	0.33TrpTrp: 0.33 ± 0.011	0.346TrpTyr: 0.346 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.629TyrAla: 2.629 ± 0.033	0.185TyrCys: 0.185 ± 0.009	1.333TyrAsp: 1.333 ± 0.027	1.097TyrGlu: 1.097 ± 0.024	0.673TyrPhe: 0.673 ± 0.016	2.156TyrGly: 2.156 ± 0.029	0.39TyrHis: 0.39 ± 0.011	0.478TyrIle: 0.478 ± 0.014	0.39TyrLys: 0.39 ± 0.013	2.264TyrLeu: 2.264 ± 0.031	0.235TyrMet: 0.235 ± 0.009	0.347TyrAsn: 0.347 ± 0.013	1.115TyrPro: 1.115 ± 0.022	0.544TyrGln: 0.544 ± 0.016	1.776TyrArg: 1.776 ± 0.027	0.938TyrSer: 0.938 ± 0.021	1.198TyrThr: 1.198 ± 0.023	1.552TyrVal: 1.552 ± 0.026	0.361TyrTrp: 0.361 ± 0.011	0.434TyrTyr: 0.434 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8804 proteins (2882551 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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