Amino acid dipepetide frequency for Hubei sobemo-like virus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.569AlaAla: 7.569 ± 0.386
0.0AlaCys: 0.0 ± 0.0
1.892AlaAsp: 1.892 ± 0.256
5.676AlaGlu: 5.676 ± 0.769
0.946AlaPhe: 0.946 ± 0.577
2.838AlaGly: 2.838 ± 1.732
0.946AlaHis: 0.946 ± 0.577
6.623AlaIle: 6.623 ± 1.219
3.784AlaLys: 3.784 ± 2.309
6.623AlaLeu: 6.623 ± 4.041
2.838AlaMet: 2.838 ± 0.321
2.838AlaAsn: 2.838 ± 1.732
3.784AlaPro: 3.784 ± 1.923
1.892AlaGln: 1.892 ± 1.667
4.73AlaArg: 4.73 ± 0.065
3.784AlaSer: 3.784 ± 0.898
3.784AlaThr: 3.784 ± 0.898
3.784AlaVal: 3.784 ± 0.898
0.946AlaTrp: 0.946 ± 0.577
4.73AlaTyr: 4.73 ± 0.065
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.946CysAsp: 0.946 ± 0.577
2.838CysGlu: 2.838 ± 0.321
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.892CysLeu: 1.892 ± 1.155
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.946CysPro: 0.946 ± 0.577
1.892CysGln: 1.892 ± 1.155
2.838CysArg: 2.838 ± 1.732
1.892CysSer: 1.892 ± 0.256
0.946CysThr: 0.946 ± 0.577
0.946CysVal: 0.946 ± 0.834
0.0CysTrp: 0.0 ± 0.0
2.838CysTyr: 2.838 ± 0.321
0.0CysXaa: 0.0 ± 0.0
Asp
0.946AspAla: 0.946 ± 0.577
0.0AspCys: 0.0 ± 0.0
1.892AspAsp: 1.892 ± 0.256
1.892AspGlu: 1.892 ± 1.155
1.892AspPhe: 1.892 ± 0.256
4.73AspGly: 4.73 ± 2.757
1.892AspHis: 1.892 ± 0.256
0.946AspIle: 0.946 ± 0.834
2.838AspLys: 2.838 ± 2.501
3.784AspLeu: 3.784 ± 0.513
1.892AspMet: 1.892 ± 1.667
0.946AspAsn: 0.946 ± 0.834
3.784AspPro: 3.784 ± 1.923
0.946AspGln: 0.946 ± 0.834
0.946AspArg: 0.946 ± 0.834
0.946AspSer: 0.946 ± 0.577
3.784AspThr: 3.784 ± 0.898
0.946AspVal: 0.946 ± 0.834
3.784AspTrp: 3.784 ± 1.923
3.784AspTyr: 3.784 ± 2.309
0.0AspXaa: 0.0 ± 0.0
Glu
7.569GluAla: 7.569 ± 0.386
0.0GluCys: 0.0 ± 0.0
4.73GluAsp: 4.73 ± 1.346
5.676GluGlu: 5.676 ± 2.053
1.892GluPhe: 1.892 ± 0.256
2.838GluGly: 2.838 ± 1.732
0.0GluHis: 0.0 ± 0.0
3.784GluIle: 3.784 ± 0.898
4.73GluLys: 4.73 ± 1.476
5.676GluLeu: 5.676 ± 2.18
1.892GluMet: 1.892 ± 0.256
2.838GluAsn: 2.838 ± 0.321
4.73GluPro: 4.73 ± 2.757
1.892GluGln: 1.892 ± 1.667
5.676GluArg: 5.676 ± 0.642
6.623GluSer: 6.623 ± 2.63
3.784GluThr: 3.784 ± 2.309
5.676GluVal: 5.676 ± 0.769
0.946GluTrp: 0.946 ± 0.834
1.892GluTyr: 1.892 ± 1.667
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.946PheCys: 0.946 ± 0.577
1.892PheAsp: 1.892 ± 1.667
1.892PheGlu: 1.892 ± 1.667
0.0PhePhe: 0.0 ± 0.0
5.676PheGly: 5.676 ± 0.769
0.0PheHis: 0.0 ± 0.0
0.946PheIle: 0.946 ± 0.834
0.0PheLys: 0.0 ± 0.0
6.623PheLeu: 6.623 ± 1.602
0.0PheMet: 0.0 ± 0.0
1.892PheAsn: 1.892 ± 0.256
0.946PhePro: 0.946 ± 0.834
0.0PheGln: 0.0 ± 0.0
1.892PheArg: 1.892 ± 0.256
0.946PheSer: 0.946 ± 0.834
0.0PheThr: 0.0 ± 0.0
0.946PheVal: 0.946 ± 0.834
0.0PheTrp: 0.0 ± 0.0
0.946PheTyr: 0.946 ± 0.577
0.0PheXaa: 0.0 ± 0.0
Gly
4.73GlyAla: 4.73 ± 2.887
2.838GlyCys: 2.838 ± 0.321
1.892GlyAsp: 1.892 ± 1.667
4.73GlyGlu: 4.73 ± 0.065
1.892GlyPhe: 1.892 ± 1.667
5.676GlyGly: 5.676 ± 2.18
0.946GlyHis: 0.946 ± 0.834
4.73GlyIle: 4.73 ± 2.887
5.676GlyLys: 5.676 ± 2.053
2.838GlyLeu: 2.838 ± 0.321
0.946GlyMet: 0.946 ± 0.577
0.946GlyAsn: 0.946 ± 0.577
3.784GlyPro: 3.784 ± 0.513
1.892GlyGln: 1.892 ± 0.256
4.73GlyArg: 4.73 ± 1.476
5.676GlySer: 5.676 ± 3.464
0.946GlyThr: 0.946 ± 0.577
4.73GlyVal: 4.73 ± 1.346
3.784GlyTrp: 3.784 ± 3.334
3.784GlyTyr: 3.784 ± 1.923
0.0GlyXaa: 0.0 ± 0.0
His
2.838HisAla: 2.838 ± 2.501
0.946HisCys: 0.946 ± 0.577
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.946HisPhe: 0.946 ± 0.834
0.946HisGly: 0.946 ± 0.577
0.946HisHis: 0.946 ± 0.577
1.892HisIle: 1.892 ± 1.155
0.946HisLys: 0.946 ± 0.834
2.838HisLeu: 2.838 ± 0.321
1.892HisMet: 1.892 ± 0.256
0.0HisAsn: 0.0 ± 0.0
0.946HisPro: 0.946 ± 0.577
0.946HisGln: 0.946 ± 0.577
1.892HisArg: 1.892 ± 0.256
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
3.784HisVal: 3.784 ± 0.898
0.0HisTrp: 0.0 ± 0.0
0.946HisTyr: 0.946 ± 0.834
0.0HisXaa: 0.0 ± 0.0
Ile
3.784IleAla: 3.784 ± 0.513
0.0IleCys: 0.0 ± 0.0
1.892IleAsp: 1.892 ± 0.256
4.73IleGlu: 4.73 ± 2.887
1.892IlePhe: 1.892 ± 1.667
2.838IleGly: 2.838 ± 1.09
1.892IleHis: 1.892 ± 1.155
0.0IleIle: 0.0 ± 0.0
0.946IleLys: 0.946 ± 0.834
5.676IleLeu: 5.676 ± 3.591
0.0IleMet: 0.0 ± 0.0
0.0IleAsn: 0.0 ± 0.0
4.73IlePro: 4.73 ± 0.065
1.892IleGln: 1.892 ± 1.155
4.73IleArg: 4.73 ± 0.065
3.784IleSer: 3.784 ± 0.898
0.0IleThr: 0.0 ± 0.0
2.838IleVal: 2.838 ± 1.09
0.946IleTrp: 0.946 ± 0.577
0.946IleTyr: 0.946 ± 0.577
0.0IleXaa: 0.0 ± 0.0
Lys
3.784LysAla: 3.784 ± 0.513
0.0LysCys: 0.0 ± 0.0
1.892LysAsp: 1.892 ± 1.155
1.892LysGlu: 1.892 ± 1.155
0.946LysPhe: 0.946 ± 0.834
2.838LysGly: 2.838 ± 0.321
0.946LysHis: 0.946 ± 0.834
0.946LysIle: 0.946 ± 0.834
5.676LysLys: 5.676 ± 0.642
7.569LysLeu: 7.569 ± 1.797
0.0LysMet: 0.0 ± 0.0
0.946LysAsn: 0.946 ± 0.834
0.0LysPro: 0.0 ± 0.0
1.892LysGln: 1.892 ± 1.667
1.892LysArg: 1.892 ± 0.256
3.784LysSer: 3.784 ± 0.513
2.838LysThr: 2.838 ± 0.321
7.569LysVal: 7.569 ± 3.208
0.946LysTrp: 0.946 ± 0.577
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.676LeuAla: 5.676 ± 0.642
1.892LeuCys: 1.892 ± 0.256
5.676LeuAsp: 5.676 ± 0.769
11.353LeuGlu: 11.353 ± 2.695
5.676LeuPhe: 5.676 ± 3.591
8.515LeuGly: 8.515 ± 0.963
2.838LeuHis: 2.838 ± 1.09
2.838LeuIle: 2.838 ± 2.501
3.784LeuLys: 3.784 ± 0.513
13.245LeuLeu: 13.245 ± 5.261
4.73LeuMet: 4.73 ± 1.476
2.838LeuAsn: 2.838 ± 1.09
3.784LeuPro: 3.784 ± 0.898
1.892LeuGln: 1.892 ± 0.256
5.676LeuArg: 5.676 ± 3.591
5.676LeuSer: 5.676 ± 0.642
0.946LeuThr: 0.946 ± 0.577
6.623LeuVal: 6.623 ± 2.63
1.892LeuTrp: 1.892 ± 0.256
1.892LeuTyr: 1.892 ± 1.667
0.0LeuXaa: 0.0 ± 0.0
Met
3.784MetAla: 3.784 ± 2.309
0.0MetCys: 0.0 ± 0.0
1.892MetAsp: 1.892 ± 1.155
3.784MetGlu: 3.784 ± 0.898
0.0MetPhe: 0.0 ± 0.0
2.838MetGly: 2.838 ± 1.09
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.946MetLys: 0.946 ± 0.834
0.946MetLeu: 0.946 ± 0.834
1.892MetMet: 1.892 ± 0.256
0.946MetAsn: 0.946 ± 0.834
0.0MetPro: 0.0 ± 0.0
1.892MetGln: 1.892 ± 0.256
2.838MetArg: 2.838 ± 1.09
4.73MetSer: 4.73 ± 0.065
0.946MetThr: 0.946 ± 0.577
1.892MetVal: 1.892 ± 0.256
0.946MetTrp: 0.946 ± 0.834
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.892AsnAla: 1.892 ± 1.155
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.946AsnGlu: 0.946 ± 0.834
0.0AsnPhe: 0.0 ± 0.0
0.946AsnGly: 0.946 ± 0.577
1.892AsnHis: 1.892 ± 1.155
0.946AsnIle: 0.946 ± 0.577
1.892AsnLys: 1.892 ± 1.155
2.838AsnLeu: 2.838 ± 0.321
0.0AsnMet: 0.0 ± 0.0
2.838AsnAsn: 2.838 ± 1.732
1.892AsnPro: 1.892 ± 1.667
2.838AsnGln: 2.838 ± 0.321
1.892AsnArg: 1.892 ± 0.256
2.838AsnSer: 2.838 ± 1.09
2.838AsnThr: 2.838 ± 0.321
3.784AsnVal: 3.784 ± 0.513
0.946AsnTrp: 0.946 ± 0.834
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.892ProAla: 1.892 ± 1.155
1.892ProCys: 1.892 ± 1.155
2.838ProAsp: 2.838 ± 1.09
6.623ProGlu: 6.623 ± 4.424
0.946ProPhe: 0.946 ± 0.577
1.892ProGly: 1.892 ± 1.667
1.892ProHis: 1.892 ± 0.256
1.892ProIle: 1.892 ± 0.256
3.784ProLys: 3.784 ± 0.513
4.73ProLeu: 4.73 ± 1.346
0.0ProMet: 0.0 ± 0.0
0.946ProAsn: 0.946 ± 0.577
0.946ProPro: 0.946 ± 0.577
0.0ProGln: 0.0 ± 0.0
2.838ProArg: 2.838 ± 1.09
7.569ProSer: 7.569 ± 1.025
0.946ProThr: 0.946 ± 0.834
3.784ProVal: 3.784 ± 0.898
0.0ProTrp: 0.0 ± 0.0
0.946ProTyr: 0.946 ± 0.834
0.0ProXaa: 0.0 ± 0.0
Gln
0.946GlnAla: 0.946 ± 0.577
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.838GlnGlu: 2.838 ± 1.09
2.838GlnPhe: 2.838 ± 1.09
4.73GlnGly: 4.73 ± 1.476
0.0GlnHis: 0.0 ± 0.0
2.838GlnIle: 2.838 ± 0.321
0.946GlnLys: 0.946 ± 0.834
1.892GlnLeu: 1.892 ± 1.667
0.946GlnMet: 0.946 ± 0.834
2.838GlnAsn: 2.838 ± 0.321
0.0GlnPro: 0.0 ± 0.0
0.946GlnGln: 0.946 ± 0.577
1.892GlnArg: 1.892 ± 1.155
3.784GlnSer: 3.784 ± 0.513
0.946GlnThr: 0.946 ± 0.577
2.838GlnVal: 2.838 ± 1.09
0.946GlnTrp: 0.946 ± 0.834
2.838GlnTyr: 2.838 ± 1.09
0.0GlnXaa: 0.0 ± 0.0
Arg
2.838ArgAla: 2.838 ± 1.09
0.946ArgCys: 0.946 ± 0.577
4.73ArgAsp: 4.73 ± 4.168
6.623ArgGlu: 6.623 ± 1.602
1.892ArgPhe: 1.892 ± 1.667
1.892ArgGly: 1.892 ± 0.256
0.946ArgHis: 0.946 ± 0.577
2.838ArgIle: 2.838 ± 0.321
0.946ArgLys: 0.946 ± 0.577
7.569ArgLeu: 7.569 ± 2.436
1.892ArgMet: 1.892 ± 0.256
2.838ArgAsn: 2.838 ± 1.732
1.892ArgPro: 1.892 ± 0.256
1.892ArgGln: 1.892 ± 0.256
4.73ArgArg: 4.73 ± 0.065
11.353ArgSer: 11.353 ± 1.284
3.784ArgThr: 3.784 ± 0.898
6.623ArgVal: 6.623 ± 0.192
1.892ArgTrp: 1.892 ± 1.155
3.784ArgTyr: 3.784 ± 0.513
0.0ArgXaa: 0.0 ± 0.0
Ser
10.407SerAla: 10.407 ± 3.529
1.892SerCys: 1.892 ± 1.155
4.73SerAsp: 4.73 ± 0.065
0.946SerGlu: 0.946 ± 0.577
2.838SerPhe: 2.838 ± 1.732
6.623SerGly: 6.623 ± 0.192
3.784SerHis: 3.784 ± 0.513
5.676SerIle: 5.676 ± 3.591
4.73SerLys: 4.73 ± 1.476
11.353SerLeu: 11.353 ± 1.284
1.892SerMet: 1.892 ± 0.93
0.946SerAsn: 0.946 ± 0.834
6.623SerPro: 6.623 ± 1.219
5.676SerGln: 5.676 ± 0.642
3.784SerArg: 3.784 ± 0.898
13.245SerSer: 13.245 ± 2.439
1.892SerThr: 1.892 ± 1.155
2.838SerVal: 2.838 ± 1.09
3.784SerTrp: 3.784 ± 1.923
1.892SerTyr: 1.892 ± 0.256
0.0SerXaa: 0.0 ± 0.0
Thr
2.838ThrAla: 2.838 ± 1.732
1.892ThrCys: 1.892 ± 1.155
0.946ThrAsp: 0.946 ± 0.577
1.892ThrGlu: 1.892 ± 1.155
0.0ThrPhe: 0.0 ± 0.0
7.569ThrGly: 7.569 ± 4.618
0.946ThrHis: 0.946 ± 0.577
1.892ThrIle: 1.892 ± 0.256
0.946ThrLys: 0.946 ± 0.577
1.892ThrLeu: 1.892 ± 1.155
0.946ThrMet: 0.946 ± 0.834
2.838ThrAsn: 2.838 ± 0.321
0.946ThrPro: 0.946 ± 0.577
0.946ThrGln: 0.946 ± 0.577
3.784ThrArg: 3.784 ± 0.513
3.784ThrSer: 3.784 ± 0.513
5.676ThrThr: 5.676 ± 3.464
1.892ThrVal: 1.892 ± 1.155
1.892ThrTrp: 1.892 ± 0.256
0.946ThrTyr: 0.946 ± 0.834
0.0ThrXaa: 0.0 ± 0.0
Val
3.784ValAla: 3.784 ± 0.513
1.892ValCys: 1.892 ± 1.667
3.784ValAsp: 3.784 ± 1.923
4.73ValGlu: 4.73 ± 1.346
0.946ValPhe: 0.946 ± 0.577
0.946ValGly: 0.946 ± 0.577
0.946ValHis: 0.946 ± 0.577
1.892ValIle: 1.892 ± 1.155
2.838ValLys: 2.838 ± 0.321
4.73ValLeu: 4.73 ± 0.065
3.784ValMet: 3.784 ± 0.898
2.838ValAsn: 2.838 ± 1.09
4.73ValPro: 4.73 ± 1.346
2.838ValGln: 2.838 ± 1.09
7.569ValArg: 7.569 ± 0.386
7.569ValSer: 7.569 ± 0.386
7.569ValThr: 7.569 ± 3.208
10.407ValVal: 10.407 ± 0.707
0.0ValTrp: 0.0 ± 0.0
4.73ValTyr: 4.73 ± 2.887
0.0ValXaa: 0.0 ± 0.0
Trp
1.892TrpAla: 1.892 ± 1.155
0.946TrpCys: 0.946 ± 0.577
0.946TrpAsp: 0.946 ± 0.834
0.946TrpGlu: 0.946 ± 0.834
0.0TrpPhe: 0.0 ± 0.0
0.946TrpGly: 0.946 ± 0.834
0.0TrpHis: 0.0 ± 0.0
0.946TrpIle: 0.946 ± 0.834
0.0TrpLys: 0.0 ± 0.0
1.892TrpLeu: 1.892 ± 1.667
2.838TrpMet: 2.838 ± 0.321
0.0TrpAsn: 0.0 ± 0.0
0.946TrpPro: 0.946 ± 0.834
0.0TrpGln: 0.0 ± 0.0
1.892TrpArg: 1.892 ± 1.667
3.784TrpSer: 3.784 ± 0.513
1.892TrpThr: 1.892 ± 1.667
3.784TrpVal: 3.784 ± 0.513
0.946TrpTrp: 0.946 ± 0.577
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.838TyrAla: 2.838 ± 0.321
1.892TyrCys: 1.892 ± 1.155
0.0TyrAsp: 0.0 ± 0.0
2.838TyrGlu: 2.838 ± 0.321
0.0TyrPhe: 0.0 ± 0.0
1.892TyrGly: 1.892 ± 0.256
1.892TyrHis: 1.892 ± 1.667
1.892TyrIle: 1.892 ± 0.256
0.946TyrLys: 0.946 ± 0.834
2.838TyrLeu: 2.838 ± 0.321
0.946TyrMet: 0.946 ± 1.297
0.946TyrAsn: 0.946 ± 0.577
0.946TyrPro: 0.946 ± 0.834
2.838TyrGln: 2.838 ± 1.09
5.676TyrArg: 5.676 ± 2.18
3.784TyrSer: 3.784 ± 0.898
0.946TyrThr: 0.946 ± 0.577
2.838TyrVal: 2.838 ± 1.732
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1058 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski