Amino acid dipepetide frequency for Thecamonas trahens ATCC 50062

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	25.926AlaAla: 25.926 ± 0.187	1.554AlaCys: 1.554 ± 0.023	7.768AlaAsp: 7.768 ± 0.056	8.519AlaGlu: 8.519 ± 0.118	3.813AlaPhe: 3.813 ± 0.031	9.801AlaGly: 9.801 ± 0.062	2.851AlaHis: 2.851 ± 0.024	4.159AlaIle: 4.159 ± 0.032	4.977AlaLys: 4.977 ± 0.053	14.296AlaLeu: 14.296 ± 0.08	2.829AlaMet: 2.829 ± 0.023	3.02AlaAsn: 3.02 ± 0.027	7.557AlaPro: 7.557 ± 0.058	4.009AlaGln: 4.009 ± 0.052	9.104AlaArg: 9.104 ± 0.071	12.895AlaSer: 12.895 ± 0.066	7.807AlaThr: 7.807 ± 0.051	10.453AlaVal: 10.453 ± 0.056	1.503AlaTrp: 1.503 ± 0.019	2.425AlaTyr: 2.425 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.355CysAla: 1.355 ± 0.022	0.25CysCys: 0.25 ± 0.009	0.681CysAsp: 0.681 ± 0.014	0.642CysGlu: 0.642 ± 0.014	0.415CysPhe: 0.415 ± 0.01	1.182CysGly: 1.182 ± 0.021	0.243CysHis: 0.243 ± 0.006	0.458CysIle: 0.458 ± 0.009	0.38CysLys: 0.38 ± 0.009	0.996CysLeu: 0.996 ± 0.015	0.249CysMet: 0.249 ± 0.006	0.35CysAsn: 0.35 ± 0.011	0.715CysPro: 0.715 ± 0.019	0.261CysGln: 0.261 ± 0.007	0.636CysArg: 0.636 ± 0.013	1.072CysSer: 1.072 ± 0.023	0.732CysThr: 0.732 ± 0.016	0.986CysVal: 0.986 ± 0.019	0.135CysTrp: 0.135 ± 0.005	0.264CysTyr: 0.264 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	9.026AspAla: 9.026 ± 0.06	0.519AspCys: 0.519 ± 0.011	5.543AspAsp: 5.543 ± 0.062	4.248AspGlu: 4.248 ± 0.037	1.526AspPhe: 1.526 ± 0.018	5.487AspGly: 5.487 ± 0.056	0.976AspHis: 0.976 ± 0.013	1.988AspIle: 1.988 ± 0.021	1.667AspLys: 1.667 ± 0.024	4.698AspLeu: 4.698 ± 0.038	1.176AspMet: 1.176 ± 0.014	1.418AspAsn: 1.418 ± 0.016	2.776AspPro: 2.776 ± 0.025	1.004AspGln: 1.004 ± 0.013	2.395AspArg: 2.395 ± 0.027	4.089AspSer: 4.089 ± 0.034	2.433AspThr: 2.433 ± 0.025	4.933AspVal: 4.933 ± 0.037	0.524AspTrp: 0.524 ± 0.01	1.092AspTyr: 1.092 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	9.213GluAla: 9.213 ± 0.107	0.652GluCys: 0.652 ± 0.014	2.445GluAsp: 2.445 ± 0.026	3.033GluGlu: 3.033 ± 0.041	1.566GluPhe: 1.566 ± 0.017	2.682GluGly: 2.682 ± 0.022	1.212GluHis: 1.212 ± 0.017	1.661GluIle: 1.661 ± 0.019	1.514GluLys: 1.514 ± 0.024	7.616GluLeu: 7.616 ± 0.086	1.208GluMet: 1.208 ± 0.017	1.109GluAsn: 1.109 ± 0.016	3.049GluPro: 3.049 ± 0.039	1.677GluGln: 1.677 ± 0.027	3.781GluArg: 3.781 ± 0.051	4.106GluSer: 4.106 ± 0.036	3.054GluThr: 3.054 ± 0.029	4.035GluVal: 4.035 ± 0.035	0.75GluTrp: 0.75 ± 0.012	1.378GluTyr: 1.378 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.837PheAla: 3.837 ± 0.031	0.433PheCys: 0.433 ± 0.009	2.22PheAsp: 2.22 ± 0.024	1.766PheGlu: 1.766 ± 0.02	1.104PhePhe: 1.104 ± 0.018	2.517PheGly: 2.517 ± 0.027	0.669PheHis: 0.669 ± 0.012	0.952PheIle: 0.952 ± 0.013	0.952PheLys: 0.952 ± 0.018	2.572PheLeu: 2.572 ± 0.026	0.573PheMet: 0.573 ± 0.01	0.904PheAsn: 0.904 ± 0.014	1.332PhePro: 1.332 ± 0.018	0.701PheGln: 0.701 ± 0.014	1.584PheArg: 1.584 ± 0.019	2.297PheSer: 2.297 ± 0.023	1.604PheThr: 1.604 ± 0.024	3.031PheVal: 3.031 ± 0.029	0.351PheTrp: 0.351 ± 0.008	0.724PheTyr: 0.724 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	8.613GlyAla: 8.613 ± 0.061	0.961GlyCys: 0.961 ± 0.018	4.175GlyAsp: 4.175 ± 0.04	4.037GlyGlu: 4.037 ± 0.032	2.2GlyPhe: 2.2 ± 0.032	7.356GlyGly: 7.356 ± 0.109	1.55GlyHis: 1.55 ± 0.02	2.328GlyIle: 2.328 ± 0.026	2.925GlyLys: 2.925 ± 0.035	6.337GlyLeu: 6.337 ± 0.044	1.606GlyMet: 1.606 ± 0.017	1.776GlyAsn: 1.776 ± 0.022	3.245GlyPro: 3.245 ± 0.029	1.658GlyGln: 1.658 ± 0.018	4.17GlyArg: 4.17 ± 0.035	7.443GlySer: 7.443 ± 0.059	3.906GlyThr: 3.906 ± 0.036	5.44GlyVal: 5.44 ± 0.04	0.934GlyTrp: 0.934 ± 0.015	1.731GlyTyr: 1.731 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	3.008HisAla: 3.008 ± 0.025	0.277HisCys: 0.277 ± 0.008	1.15HisAsp: 1.15 ± 0.014	1.075HisGlu: 1.075 ± 0.015	0.668HisPhe: 0.668 ± 0.01	1.661HisGly: 1.661 ± 0.02	0.598HisHis: 0.598 ± 0.013	0.856HisIle: 0.856 ± 0.011	0.671HisLys: 0.671 ± 0.01	2.061HisLeu: 2.061 ± 0.022	0.452HisMet: 0.452 ± 0.008	0.603HisAsn: 0.603 ± 0.01	1.4HisPro: 1.4 ± 0.016	0.504HisGln: 0.504 ± 0.011	1.271HisArg: 1.271 ± 0.016	1.516HisSer: 1.516 ± 0.02	1.202HisThr: 1.202 ± 0.016	1.801HisVal: 1.801 ± 0.019	0.24HisTrp: 0.24 ± 0.006	0.515HisTyr: 0.515 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.154IleAla: 4.154 ± 0.032	0.412IleCys: 0.412 ± 0.008	2.288IleAsp: 2.288 ± 0.023	2.051IleGlu: 2.051 ± 0.02	1.05IlePhe: 1.05 ± 0.015	2.27IleGly: 2.27 ± 0.023	0.789IleHis: 0.789 ± 0.012	1.253IleIle: 1.253 ± 0.022	1.208IleLys: 1.208 ± 0.017	2.781IleLeu: 2.781 ± 0.029	0.679IleMet: 0.679 ± 0.011	1.049IleAsn: 1.049 ± 0.015	1.647IlePro: 1.647 ± 0.019	0.901IleGln: 0.901 ± 0.014	2.083IleArg: 2.083 ± 0.02	2.4IleSer: 2.4 ± 0.02	1.797IleThr: 1.797 ± 0.023	2.886IleVal: 2.886 ± 0.024	0.275IleTrp: 0.275 ± 0.006	0.671IleTyr: 0.671 ± 0.012	0.0IleXaa: 0.0 ± 0.0
Lys	4.991LysAla: 4.991 ± 0.049	0.334LysCys: 0.334 ± 0.009	1.47LysAsp: 1.47 ± 0.02	1.464LysGlu: 1.464 ± 0.022	0.915LysPhe: 0.915 ± 0.013	1.919LysGly: 1.919 ± 0.035	0.77LysHis: 0.77 ± 0.011	1.132LysIle: 1.132 ± 0.015	1.826LysLys: 1.826 ± 0.043	3.456LysLeu: 3.456 ± 0.03	0.655LysMet: 0.655 ± 0.011	0.71LysAsn: 0.71 ± 0.012	1.736LysPro: 1.736 ± 0.024	0.894LysGln: 0.894 ± 0.015	2.647LysArg: 2.647 ± 0.032	2.604LysSer: 2.604 ± 0.032	1.863LysThr: 1.863 ± 0.019	2.348LysVal: 2.348 ± 0.021	0.377LysTrp: 0.377 ± 0.007	0.845LysTyr: 0.845 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	15.304LeuAla: 15.304 ± 0.084	1.153LeuCys: 1.153 ± 0.016	6.4LeuAsp: 6.4 ± 0.043	6.064LeuGlu: 6.064 ± 0.075	3.075LeuPhe: 3.075 ± 0.026	6.415LeuGly: 6.415 ± 0.035	2.28LeuHis: 2.28 ± 0.024	2.834LeuIle: 2.834 ± 0.026	2.838LeuLys: 2.838 ± 0.03	9.341LeuLeu: 9.341 ± 0.071	1.73LeuMet: 1.73 ± 0.019	2.319LeuAsn: 2.319 ± 0.023	5.761LeuPro: 5.761 ± 0.044	2.848LeuGln: 2.848 ± 0.031	6.545LeuArg: 6.545 ± 0.05	7.089LeuSer: 7.089 ± 0.036	5.066LeuThr: 5.066 ± 0.033	8.511LeuVal: 8.511 ± 0.048	0.978LeuTrp: 0.978 ± 0.014	2.037LeuTyr: 2.037 ± 0.02	0.0LeuXaa: 0.0 ± 0.0
Met	3.151MetAla: 3.151 ± 0.024	0.253MetCys: 0.253 ± 0.007	1.102MetAsp: 1.102 ± 0.014	1.103MetGlu: 1.103 ± 0.021	0.672MetPhe: 0.672 ± 0.011	1.309MetGly: 1.309 ± 0.019	0.468MetHis: 0.468 ± 0.009	0.605MetIle: 0.605 ± 0.01	0.455MetLys: 0.455 ± 0.01	2.161MetLeu: 2.161 ± 0.018	0.526MetMet: 0.526 ± 0.017	0.353MetAsn: 0.353 ± 0.007	1.159MetPro: 1.159 ± 0.014	0.643MetGln: 0.643 ± 0.012	1.35MetArg: 1.35 ± 0.017	1.54MetSer: 1.54 ± 0.018	1.124MetThr: 1.124 ± 0.014	1.662MetVal: 1.662 ± 0.017	0.255MetTrp: 0.255 ± 0.006	0.532MetTyr: 0.532 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.171AsnAla: 3.171 ± 0.024	0.291AsnCys: 0.291 ± 0.008	1.384AsnAsp: 1.384 ± 0.021	1.401AsnGlu: 1.401 ± 0.021	0.673AsnPhe: 0.673 ± 0.013	1.821AsnGly: 1.821 ± 0.023	0.471AsnHis: 0.471 ± 0.01	0.983AsnIle: 0.983 ± 0.015	0.908AsnLys: 0.908 ± 0.014	1.986AsnLeu: 1.986 ± 0.022	0.566AsnMet: 0.566 ± 0.009	0.81AsnAsn: 0.81 ± 0.019	1.31AsnPro: 1.31 ± 0.019	0.555AsnGln: 0.555 ± 0.01	1.156AsnArg: 1.156 ± 0.013	1.781AsnSer: 1.781 ± 0.021	1.338AsnThr: 1.338 ± 0.018	2.025AsnVal: 2.025 ± 0.021	0.253AsnTrp: 0.253 ± 0.008	0.605AsnTyr: 0.605 ± 0.011	0.0AsnXaa: 0.0 ± 0.0
Pro	7.66ProAla: 7.66 ± 0.063	0.541ProCys: 0.541 ± 0.012	3.028ProAsp: 3.028 ± 0.028	2.976ProGlu: 2.976 ± 0.034	1.523ProPhe: 1.523 ± 0.017	3.962ProGly: 3.962 ± 0.036	1.389ProHis: 1.389 ± 0.017	1.607ProIle: 1.607 ± 0.02	1.417ProLys: 1.417 ± 0.019	5.502ProLeu: 5.502 ± 0.038	1.016ProMet: 1.016 ± 0.012	1.206ProAsn: 1.206 ± 0.015	5.729ProPro: 5.729 ± 0.075	1.674ProGln: 1.674 ± 0.018	3.44ProArg: 3.44 ± 0.03	5.592ProSer: 5.592 ± 0.046	3.16ProThr: 3.16 ± 0.032	3.942ProVal: 3.942 ± 0.035	0.602ProTrp: 0.602 ± 0.009	1.032ProTyr: 1.032 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.994GlnAla: 3.994 ± 0.056	0.31GlnCys: 0.31 ± 0.009	0.983GlnAsp: 0.983 ± 0.013	1.178GlnGlu: 1.178 ± 0.02	0.861GlnPhe: 0.861 ± 0.012	1.351GlnGly: 1.351 ± 0.015	0.639GlnHis: 0.639 ± 0.011	0.993GlnIle: 0.993 ± 0.014	0.644GlnLys: 0.644 ± 0.012	3.643GlnLeu: 3.643 ± 0.041	0.629GlnMet: 0.629 ± 0.012	0.498GlnAsn: 0.498 ± 0.01	1.517GlnPro: 1.517 ± 0.019	1.146GlnGln: 1.146 ± 0.023	1.899GlnArg: 1.899 ± 0.022	1.781GlnSer: 1.781 ± 0.022	1.383GlnThr: 1.383 ± 0.017	2.12GlnVal: 2.12 ± 0.023	0.333GlnTrp: 0.333 ± 0.008	0.636GlnTyr: 0.636 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	8.381ArgAla: 8.381 ± 0.066	0.672ArgCys: 0.672 ± 0.013	3.117ArgAsp: 3.117 ± 0.032	3.608ArgGlu: 3.608 ± 0.045	1.72ArgPhe: 1.72 ± 0.021	4.143ArgGly: 4.143 ± 0.034	1.405ArgHis: 1.405 ± 0.018	2.363ArgIle: 2.363 ± 0.019	2.973ArgLys: 2.973 ± 0.028	6.048ArgLeu: 6.048 ± 0.038	1.418ArgMet: 1.418 ± 0.015	1.567ArgAsn: 1.567 ± 0.02	3.056ArgPro: 3.056 ± 0.029	1.75ArgGln: 1.75 ± 0.021	5.317ArgArg: 5.317 ± 0.048	5.264ArgSer: 5.264 ± 0.04	3.255ArgThr: 3.255 ± 0.028	4.545ArgVal: 4.545 ± 0.033	0.69ArgTrp: 0.69 ± 0.01	1.302ArgTyr: 1.302 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	10.618SerAla: 10.618 ± 0.048	0.99SerCys: 0.99 ± 0.024	4.478SerAsp: 4.478 ± 0.035	3.897SerGlu: 3.897 ± 0.033	2.476SerPhe: 2.476 ± 0.026	7.428SerGly: 7.428 ± 0.062	1.689SerHis: 1.689 ± 0.019	2.609SerIle: 2.609 ± 0.022	2.746SerLys: 2.746 ± 0.034	8.255SerLeu: 8.255 ± 0.046	1.74SerMet: 1.74 ± 0.017	1.794SerAsn: 1.794 ± 0.02	5.671SerPro: 5.671 ± 0.046	2.183SerGln: 2.183 ± 0.025	5.413SerArg: 5.413 ± 0.041	10.628SerSer: 10.628 ± 0.102	4.521SerThr: 4.521 ± 0.04	5.741SerVal: 5.741 ± 0.033	0.93SerTrp: 0.93 ± 0.016	1.621SerTyr: 1.621 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	7.251ThrAla: 7.251 ± 0.051	0.765ThrCys: 0.765 ± 0.02	2.524ThrAsp: 2.524 ± 0.03	2.539ThrGlu: 2.539 ± 0.03	1.803ThrPhe: 1.803 ± 0.025	3.935ThrGly: 3.935 ± 0.036	1.057ThrHis: 1.057 ± 0.014	1.994ThrIle: 1.994 ± 0.024	1.754ThrLys: 1.754 ± 0.023	5.538ThrLeu: 5.538 ± 0.036	1.084ThrMet: 1.084 ± 0.014	1.242ThrAsn: 1.242 ± 0.015	3.812ThrPro: 3.812 ± 0.034	1.338ThrGln: 1.338 ± 0.017	3.16ThrArg: 3.16 ± 0.026	4.95ThrSer: 4.95 ± 0.033	3.569ThrThr: 3.569 ± 0.038	4.032ThrVal: 4.032 ± 0.038	0.585ThrTrp: 0.585 ± 0.011	1.138ThrTyr: 1.138 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	11.753ValAla: 11.753 ± 0.064	1.162ValCys: 1.162 ± 0.022	4.803ValAsp: 4.803 ± 0.036	4.376ValGlu: 4.376 ± 0.036	2.846ValPhe: 2.846 ± 0.024	4.906ValGly: 4.906 ± 0.033	1.659ValHis: 1.659 ± 0.019	2.601ValIle: 2.601 ± 0.023	2.074ValLys: 2.074 ± 0.022	8.002ValLeu: 8.002 ± 0.05	1.485ValMet: 1.485 ± 0.018	1.774ValAsn: 1.774 ± 0.021	4.098ValPro: 4.098 ± 0.031	1.905ValGln: 1.905 ± 0.02	4.597ValArg: 4.597 ± 0.033	5.765ValSer: 5.765 ± 0.047	4.315ValThr: 4.315 ± 0.038	8.154ValVal: 8.154 ± 0.061	1.04ValTrp: 1.04 ± 0.017	1.831ValTyr: 1.831 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.227TrpAla: 1.227 ± 0.015	0.164TrpCys: 0.164 ± 0.007	0.614TrpAsp: 0.614 ± 0.011	0.526TrpGlu: 0.526 ± 0.01	0.391TrpPhe: 0.391 ± 0.01	0.605TrpGly: 0.605 ± 0.011	0.323TrpHis: 0.323 ± 0.008	0.488TrpIle: 0.488 ± 0.01	0.335TrpLys: 0.335 ± 0.008	1.354TrpLeu: 1.354 ± 0.02	0.318TrpMet: 0.318 ± 0.008	0.301TrpAsn: 0.301 ± 0.007	0.51TrpPro: 0.51 ± 0.012	0.346TrpGln: 0.346 ± 0.008	0.891TrpArg: 0.891 ± 0.013	0.976TrpSer: 0.976 ± 0.018	0.616TrpThr: 0.616 ± 0.01	0.715TrpVal: 0.715 ± 0.012	0.213TrpTrp: 0.213 ± 0.006	0.305TrpTyr: 0.305 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.63TyrAla: 2.63 ± 0.024	0.312TyrCys: 0.312 ± 0.011	1.348TyrAsp: 1.348 ± 0.016	1.237TyrGlu: 1.237 ± 0.017	0.824TyrPhe: 0.824 ± 0.013	1.64TyrGly: 1.64 ± 0.02	0.494TyrHis: 0.494 ± 0.009	0.779TyrIle: 0.779 ± 0.011	0.69TyrLys: 0.69 ± 0.01	1.945TyrLeu: 1.945 ± 0.02	0.484TyrMet: 0.484 ± 0.009	0.687TyrAsn: 0.687 ± 0.012	0.919TyrPro: 0.919 ± 0.014	0.539TyrGln: 0.539 ± 0.01	1.154TyrArg: 1.154 ± 0.015	1.638TyrSer: 1.638 ± 0.031	1.327TyrThr: 1.327 ± 0.022	1.788TyrVal: 1.788 ± 0.02	0.249TyrTrp: 0.249 ± 0.007	0.653TyrTyr: 0.653 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10604 proteins (6918374 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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