Amino acid dipepetide frequency for Avon-Heathcote Estuary associated circular virus 15

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.882AlaAla: 5.882 ± 0.897
0.0AlaCys: 0.0 ± 0.0
2.941AlaAsp: 2.941 ± 0.448
8.824AlaGlu: 8.824 ± 0.787
2.941AlaPhe: 2.941 ± 1.684
1.471AlaGly: 1.471 ± 0.842
1.471AlaHis: 1.471 ± 0.842
8.824AlaIle: 8.824 ± 2.919
2.941AlaLys: 2.941 ± 0.448
4.412AlaLeu: 4.412 ± 2.526
1.471AlaMet: 1.471 ± 0.842
2.941AlaAsn: 2.941 ± 0.448
4.412AlaPro: 4.412 ± 0.393
0.0AlaGln: 0.0 ± 0.0
2.941AlaArg: 2.941 ± 0.448
2.941AlaSer: 2.941 ± 0.448
1.471AlaThr: 1.471 ± 1.29
7.353AlaVal: 7.353 ± 0.055
0.0AlaTrp: 0.0 ± 0.0
2.941AlaTyr: 2.941 ± 0.448
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.471CysPhe: 1.471 ± 1.29
1.471CysGly: 1.471 ± 1.29
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.471CysLys: 1.471 ± 0.842
1.471CysLeu: 1.471 ± 1.29
0.0CysMet: 0.0 ± 0.0
1.471CysAsn: 1.471 ± 1.29
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.471CysSer: 1.471 ± 0.842
1.471CysThr: 1.471 ± 0.842
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.882AspAla: 5.882 ± 1.235
0.0AspCys: 0.0 ± 0.0
4.412AspAsp: 4.412 ± 2.526
7.353AspGlu: 7.353 ± 2.077
1.471AspPhe: 1.471 ± 1.29
4.412AspGly: 4.412 ± 2.526
0.0AspHis: 0.0 ± 0.0
4.412AspIle: 4.412 ± 1.739
2.941AspLys: 2.941 ± 0.448
5.882AspLeu: 5.882 ± 1.235
0.0AspMet: 0.0 ± 0.0
4.412AspAsn: 4.412 ± 1.739
1.471AspPro: 1.471 ± 1.29
1.471AspGln: 1.471 ± 1.29
2.941AspArg: 2.941 ± 1.684
1.471AspSer: 1.471 ± 0.842
2.941AspThr: 2.941 ± 1.684
2.941AspVal: 2.941 ± 1.684
2.941AspTrp: 2.941 ± 1.684
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.941GluAla: 2.941 ± 1.684
0.0GluCys: 0.0 ± 0.0
2.941GluAsp: 2.941 ± 0.448
7.353GluGlu: 7.353 ± 4.209
4.412GluPhe: 4.412 ± 0.393
4.412GluGly: 4.412 ± 2.526
1.471GluHis: 1.471 ± 0.842
2.941GluIle: 2.941 ± 1.684
1.471GluLys: 1.471 ± 0.842
4.412GluLeu: 4.412 ± 2.526
2.941GluMet: 2.941 ± 0.448
1.471GluAsn: 1.471 ± 0.842
5.882GluPro: 5.882 ± 0.897
0.0GluGln: 0.0 ± 0.0
5.882GluArg: 5.882 ± 1.235
4.412GluSer: 4.412 ± 1.739
5.882GluThr: 5.882 ± 1.235
2.941GluVal: 2.941 ± 0.448
0.0GluTrp: 0.0 ± 0.0
1.471GluTyr: 1.471 ± 0.842
0.0GluXaa: 0.0 ± 0.0
Phe
1.471PheAla: 1.471 ± 1.29
1.471PheCys: 1.471 ± 0.842
5.882PheAsp: 5.882 ± 1.235
1.471PheGlu: 1.471 ± 1.29
0.0PhePhe: 0.0 ± 0.0
4.412PheGly: 4.412 ± 3.871
1.471PheHis: 1.471 ± 1.29
2.941PheIle: 2.941 ± 0.448
4.412PheLys: 4.412 ± 1.739
1.471PheLeu: 1.471 ± 0.842
0.0PheMet: 0.0 ± 0.0
1.471PheAsn: 1.471 ± 1.29
0.0PhePro: 0.0 ± 0.0
1.471PheGln: 1.471 ± 1.29
0.0PheArg: 0.0 ± 0.0
5.882PheSer: 5.882 ± 3.367
2.941PheThr: 2.941 ± 0.448
2.941PheVal: 2.941 ± 0.448
1.471PheTrp: 1.471 ± 1.29
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.941GlyAla: 2.941 ± 1.684
0.0GlyCys: 0.0 ± 0.0
2.941GlyAsp: 2.941 ± 1.684
4.412GlyGlu: 4.412 ± 0.393
2.941GlyPhe: 2.941 ± 1.684
10.294GlyGly: 10.294 ± 4.767
1.471GlyHis: 1.471 ± 0.842
0.0GlyIle: 0.0 ± 0.0
7.353GlyLys: 7.353 ± 4.209
2.941GlyLeu: 2.941 ± 1.684
2.941GlyMet: 2.941 ± 2.001
1.471GlyAsn: 1.471 ± 1.29
0.0GlyPro: 0.0 ± 0.0
5.882GlyGln: 5.882 ± 3.029
2.941GlyArg: 2.941 ± 2.58
8.824GlySer: 8.824 ± 1.345
8.824GlyThr: 8.824 ± 3.477
4.412GlyVal: 4.412 ± 1.739
0.0GlyTrp: 0.0 ± 0.0
1.471GlyTyr: 1.471 ± 0.842
0.0GlyXaa: 0.0 ± 0.0
His
2.941HisAla: 2.941 ± 1.684
0.0HisCys: 0.0 ± 0.0
1.471HisAsp: 1.471 ± 0.842
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.941HisIle: 2.941 ± 0.448
0.0HisLys: 0.0 ± 0.0
2.941HisLeu: 2.941 ± 1.684
1.471HisMet: 1.471 ± 0.842
1.471HisAsn: 1.471 ± 0.842
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.471HisSer: 1.471 ± 0.842
1.471HisThr: 1.471 ± 1.29
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.471HisTyr: 1.471 ± 0.842
0.0HisXaa: 0.0 ± 0.0
Ile
10.294IleAla: 10.294 ± 0.503
1.471IleCys: 1.471 ± 1.29
2.941IleAsp: 2.941 ± 0.448
7.353IleGlu: 7.353 ± 0.055
1.471IlePhe: 1.471 ± 0.842
4.412IleGly: 4.412 ± 0.393
1.471IleHis: 1.471 ± 0.842
5.882IleIle: 5.882 ± 0.897
0.0IleLys: 0.0 ± 0.0
1.471IleLeu: 1.471 ± 1.29
0.0IleMet: 0.0 ± 0.659
1.471IleAsn: 1.471 ± 0.842
1.471IlePro: 1.471 ± 0.842
0.0IleGln: 0.0 ± 0.0
4.412IleArg: 4.412 ± 1.739
4.412IleSer: 4.412 ± 0.393
2.941IleThr: 2.941 ± 2.58
7.353IleVal: 7.353 ± 0.055
1.471IleTrp: 1.471 ± 0.842
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
1.471LysAsp: 1.471 ± 1.29
2.941LysGlu: 2.941 ± 0.448
0.0LysPhe: 0.0 ± 0.0
4.412LysGly: 4.412 ± 2.526
4.412LysHis: 4.412 ± 0.393
2.941LysIle: 2.941 ± 0.448
1.471LysLys: 1.471 ± 0.842
1.471LysLeu: 1.471 ± 1.29
1.471LysMet: 1.471 ± 1.29
0.0LysAsn: 0.0 ± 0.0
2.941LysPro: 2.941 ± 1.684
7.353LysGln: 7.353 ± 2.077
4.412LysArg: 4.412 ± 1.739
5.882LysSer: 5.882 ± 1.235
1.471LysThr: 1.471 ± 0.842
0.0LysVal: 0.0 ± 0.0
2.941LysTrp: 2.941 ± 1.684
2.941LysTyr: 2.941 ± 0.448
0.0LysXaa: 0.0 ± 0.0
Leu
8.824LeuAla: 8.824 ± 2.919
1.471LeuCys: 1.471 ± 1.29
2.941LeuAsp: 2.941 ± 0.448
1.471LeuGlu: 1.471 ± 0.842
2.941LeuPhe: 2.941 ± 0.448
1.471LeuGly: 1.471 ± 1.29
1.471LeuHis: 1.471 ± 0.842
0.0LeuIle: 0.0 ± 0.0
7.353LeuLys: 7.353 ± 0.055
7.353LeuLeu: 7.353 ± 2.077
0.0LeuMet: 0.0 ± 0.0
2.941LeuAsn: 2.941 ± 0.448
1.471LeuPro: 1.471 ± 1.29
2.941LeuGln: 2.941 ± 1.684
7.353LeuArg: 7.353 ± 4.209
5.882LeuSer: 5.882 ± 3.367
2.941LeuThr: 2.941 ± 0.448
7.353LeuVal: 7.353 ± 0.055
0.0LeuTrp: 0.0 ± 0.0
1.471LeuTyr: 1.471 ± 1.29
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.471MetPhe: 1.471 ± 1.29
1.471MetGly: 1.471 ± 0.842
1.471MetHis: 1.471 ± 0.842
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
2.941MetLeu: 2.941 ± 0.448
0.0MetMet: 0.0 ± 0.0
1.471MetAsn: 1.471 ± 1.29
1.471MetPro: 1.471 ± 0.842
0.0MetGln: 0.0 ± 0.0
1.471MetArg: 1.471 ± 0.842
2.941MetSer: 2.941 ± 2.58
0.0MetThr: 0.0 ± 0.0
2.941MetVal: 2.941 ± 0.448
1.471MetTrp: 1.471 ± 0.842
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.941AsnAla: 2.941 ± 0.448
0.0AsnCys: 0.0 ± 0.0
5.882AsnAsp: 5.882 ± 0.897
0.0AsnGlu: 0.0 ± 0.0
4.412AsnPhe: 4.412 ± 3.871
2.941AsnGly: 2.941 ± 2.58
0.0AsnHis: 0.0 ± 0.0
1.471AsnIle: 1.471 ± 1.29
0.0AsnLys: 0.0 ± 0.0
1.471AsnLeu: 1.471 ± 1.29
1.471AsnMet: 1.471 ± 0.842
2.941AsnAsn: 2.941 ± 0.448
1.471AsnPro: 1.471 ± 1.29
4.412AsnGln: 4.412 ± 1.739
5.882AsnArg: 5.882 ± 0.897
4.412AsnSer: 4.412 ± 1.739
2.941AsnThr: 2.941 ± 0.448
2.941AsnVal: 2.941 ± 0.448
1.471AsnTrp: 1.471 ± 0.842
2.941AsnTyr: 2.941 ± 0.448
0.0AsnXaa: 0.0 ± 0.0
Pro
1.471ProAla: 1.471 ± 1.29
1.471ProCys: 1.471 ± 1.29
2.941ProAsp: 2.941 ± 1.684
1.471ProGlu: 1.471 ± 0.842
1.471ProPhe: 1.471 ± 0.842
2.941ProGly: 2.941 ± 0.448
1.471ProHis: 1.471 ± 0.842
1.471ProIle: 1.471 ± 1.29
1.471ProLys: 1.471 ± 0.842
2.941ProLeu: 2.941 ± 1.684
1.471ProMet: 1.471 ± 1.29
1.471ProAsn: 1.471 ± 0.842
1.471ProPro: 1.471 ± 0.842
1.471ProGln: 1.471 ± 0.842
5.882ProArg: 5.882 ± 0.897
4.412ProSer: 4.412 ± 0.393
5.882ProThr: 5.882 ± 1.235
0.0ProVal: 0.0 ± 0.0
1.471ProTrp: 1.471 ± 0.842
1.471ProTyr: 1.471 ± 1.29
0.0ProXaa: 0.0 ± 0.0
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
1.471GlnAsp: 1.471 ± 0.842
2.941GlnGlu: 2.941 ± 1.684
1.471GlnPhe: 1.471 ± 1.29
7.353GlnGly: 7.353 ± 2.187
0.0GlnHis: 0.0 ± 0.0
5.882GlnIle: 5.882 ± 3.029
0.0GlnLys: 0.0 ± 0.0
1.471GlnLeu: 1.471 ± 0.842
1.471GlnMet: 1.471 ± 1.29
4.412GlnAsn: 4.412 ± 3.871
0.0GlnPro: 0.0 ± 0.0
5.882GlnGln: 5.882 ± 0.897
4.412GlnArg: 4.412 ± 0.393
2.941GlnSer: 2.941 ± 1.684
2.941GlnThr: 2.941 ± 2.58
1.471GlnVal: 1.471 ± 1.29
0.0GlnTrp: 0.0 ± 0.0
2.941GlnTyr: 2.941 ± 0.448
0.0GlnXaa: 0.0 ± 0.0
Arg
2.941ArgAla: 2.941 ± 0.448
0.0ArgCys: 0.0 ± 0.0
1.471ArgAsp: 1.471 ± 0.842
2.941ArgGlu: 2.941 ± 0.448
2.941ArgPhe: 2.941 ± 0.448
4.412ArgGly: 4.412 ± 1.739
0.0ArgHis: 0.0 ± 0.0
2.941ArgIle: 2.941 ± 1.684
2.941ArgLys: 2.941 ± 2.58
7.353ArgLeu: 7.353 ± 2.187
0.0ArgMet: 0.0 ± 0.0
7.353ArgAsn: 7.353 ± 2.077
1.471ArgPro: 1.471 ± 1.29
1.471ArgGln: 1.471 ± 1.29
5.882ArgArg: 5.882 ± 0.897
8.824ArgSer: 8.824 ± 0.787
4.412ArgThr: 4.412 ± 0.393
4.412ArgVal: 4.412 ± 1.739
2.941ArgTrp: 2.941 ± 1.684
4.412ArgTyr: 4.412 ± 0.393
0.0ArgXaa: 0.0 ± 0.0
Ser
2.941SerAla: 2.941 ± 1.684
2.941SerCys: 2.941 ± 0.448
5.882SerAsp: 5.882 ± 3.367
7.353SerGlu: 7.353 ± 2.077
5.882SerPhe: 5.882 ± 3.029
2.941SerGly: 2.941 ± 0.448
0.0SerHis: 0.0 ± 0.0
7.353SerIle: 7.353 ± 2.187
2.941SerLys: 2.941 ± 0.448
5.882SerLeu: 5.882 ± 3.367
1.471SerMet: 1.471 ± 0.842
1.471SerAsn: 1.471 ± 1.29
7.353SerPro: 7.353 ± 2.077
1.471SerGln: 1.471 ± 1.29
8.824SerArg: 8.824 ± 1.345
8.824SerSer: 8.824 ± 2.919
5.882SerThr: 5.882 ± 1.235
1.471SerVal: 1.471 ± 0.842
0.0SerTrp: 0.0 ± 0.0
5.882SerTyr: 5.882 ± 1.235
0.0SerXaa: 0.0 ± 0.0
Thr
7.353ThrAla: 7.353 ± 0.055
0.0ThrCys: 0.0 ± 0.0
4.412ThrAsp: 4.412 ± 0.393
1.471ThrGlu: 1.471 ± 0.842
1.471ThrPhe: 1.471 ± 1.29
5.882ThrGly: 5.882 ± 0.897
1.471ThrHis: 1.471 ± 0.842
1.471ThrIle: 1.471 ± 0.842
4.412ThrLys: 4.412 ± 0.393
4.412ThrLeu: 4.412 ± 0.393
1.471ThrMet: 1.471 ± 0.842
5.882ThrAsn: 5.882 ± 5.161
5.882ThrPro: 5.882 ± 0.897
8.824ThrGln: 8.824 ± 1.345
1.471ThrArg: 1.471 ± 0.842
2.941ThrSer: 2.941 ± 1.684
5.882ThrThr: 5.882 ± 0.897
5.882ThrVal: 5.882 ± 3.029
0.0ThrTrp: 0.0 ± 0.0
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.882ValAla: 5.882 ± 1.235
0.0ValCys: 0.0 ± 0.0
2.941ValAsp: 2.941 ± 2.58
1.471ValGlu: 1.471 ± 0.842
1.471ValPhe: 1.471 ± 0.842
5.882ValGly: 5.882 ± 3.367
0.0ValHis: 0.0 ± 0.0
8.824ValIle: 8.824 ± 0.787
4.412ValLys: 4.412 ± 2.526
4.412ValLeu: 4.412 ± 3.871
0.0ValMet: 0.0 ± 0.0
4.412ValAsn: 4.412 ± 1.739
0.0ValPro: 0.0 ± 0.0
0.0ValGln: 0.0 ± 0.0
2.941ValArg: 2.941 ± 2.58
4.412ValSer: 4.412 ± 1.739
4.412ValThr: 4.412 ± 1.739
4.412ValVal: 4.412 ± 2.526
0.0ValTrp: 0.0 ± 0.0
2.941ValTyr: 2.941 ± 2.58
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.471TrpGlu: 1.471 ± 0.842
1.471TrpPhe: 1.471 ± 0.842
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.471TrpIle: 1.471 ± 0.842
1.471TrpLys: 1.471 ± 0.842
2.941TrpLeu: 2.941 ± 1.684
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.941TrpPro: 2.941 ± 1.684
1.471TrpGln: 1.471 ± 1.29
0.0TrpArg: 0.0 ± 0.0
1.471TrpSer: 1.471 ± 0.842
2.941TrpThr: 2.941 ± 1.684
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.471TyrAla: 1.471 ± 1.29
1.471TyrCys: 1.471 ± 0.842
4.412TyrAsp: 4.412 ± 2.526
2.941TyrGlu: 2.941 ± 1.684
1.471TyrPhe: 1.471 ± 1.29
1.471TyrGly: 1.471 ± 1.29
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
1.471TyrLys: 1.471 ± 1.29
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.471TyrAsn: 1.471 ± 1.29
4.412TyrPro: 4.412 ± 2.526
2.941TyrGln: 2.941 ± 2.58
1.471TyrArg: 1.471 ± 1.29
2.941TyrSer: 2.941 ± 0.448
2.941TyrThr: 2.941 ± 0.448
0.0TyrVal: 0.0 ± 0.0
1.471TyrTrp: 1.471 ± 0.842
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (681 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski