Amino acid dipepetide frequency for Beihai horseshoe crab virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.541AlaAla: 8.541 ± 2.001
1.314AlaCys: 1.314 ± 1.154
4.599AlaAsp: 4.599 ± 2.079
6.57AlaGlu: 6.57 ± 2.804
1.314AlaPhe: 1.314 ± 0.523
5.256AlaGly: 5.256 ± 1.365
1.971AlaHis: 1.971 ± 0.987
3.942AlaIle: 3.942 ± 2.134
7.884AlaLys: 7.884 ± 1.464
9.855AlaLeu: 9.855 ± 2.494
0.657AlaMet: 0.657 ± 0.574
3.285AlaAsn: 3.285 ± 0.512
2.628AlaPro: 2.628 ± 1.53
2.628AlaGln: 2.628 ± 1.046
5.256AlaArg: 5.256 ± 2.455
5.256AlaSer: 5.256 ± 2.982
5.256AlaThr: 5.256 ± 2.274
4.599AlaVal: 4.599 ± 0.197
2.628AlaTrp: 2.628 ± 1.046
1.971AlaTyr: 1.971 ± 0.149
0.0AlaXaa: 0.0 ± 0.0
Cys
1.314CysAla: 1.314 ± 0.523
0.0CysCys: 0.0 ± 0.0
1.971CysAsp: 1.971 ± 1.067
0.657CysGlu: 0.657 ± 0.577
1.314CysPhe: 1.314 ± 0.637
1.971CysGly: 1.971 ± 0.954
0.657CysHis: 0.657 ± 0.577
0.657CysIle: 0.657 ± 0.577
0.657CysLys: 0.657 ± 0.574
0.657CysLeu: 0.657 ± 0.489
0.657CysMet: 0.657 ± 0.474
1.314CysAsn: 1.314 ± 1.154
1.314CysPro: 1.314 ± 1.149
1.314CysGln: 1.314 ± 1.149
1.314CysArg: 1.314 ± 0.494
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.314CysVal: 1.314 ± 0.978
0.0CysTrp: 0.0 ± 0.0
0.657CysTyr: 0.657 ± 0.574
0.0CysXaa: 0.0 ± 0.0
Asp
3.285AspAla: 3.285 ± 1.665
0.657AspCys: 0.657 ± 0.574
1.971AspAsp: 1.971 ± 0.954
1.971AspGlu: 1.971 ± 0.832
3.285AspPhe: 3.285 ± 1.407
3.285AspGly: 3.285 ± 1.661
1.971AspHis: 1.971 ± 0.832
3.942AspIle: 3.942 ± 1.911
1.971AspLys: 1.971 ± 1.466
2.628AspLeu: 2.628 ± 1.261
0.0AspMet: 0.0 ± 0.0
1.971AspAsn: 1.971 ± 0.798
3.942AspPro: 3.942 ± 1.596
1.971AspGln: 1.971 ± 0.149
2.628AspArg: 2.628 ± 0.341
0.657AspSer: 0.657 ± 0.574
4.599AspThr: 4.599 ± 0.759
1.971AspVal: 1.971 ± 1.73
1.971AspTrp: 1.971 ± 0.798
1.971AspTyr: 1.971 ± 1.723
0.0AspXaa: 0.0 ± 0.0
Glu
1.971GluAla: 1.971 ± 0.832
1.314GluCys: 1.314 ± 1.149
1.971GluAsp: 1.971 ± 0.149
4.599GluGlu: 4.599 ± 1.881
0.657GluPhe: 0.657 ± 0.577
1.971GluGly: 1.971 ± 1.067
0.657GluHis: 0.657 ± 0.574
1.314GluIle: 1.314 ± 0.494
6.57GluLys: 6.57 ± 2.493
6.57GluLeu: 6.57 ± 1.584
1.314GluMet: 1.314 ± 0.523
2.628GluAsn: 2.628 ± 1.591
3.285GluPro: 3.285 ± 1.407
1.971GluGln: 1.971 ± 1.466
6.57GluArg: 6.57 ± 2.804
5.256GluSer: 5.256 ± 1.226
1.314GluThr: 1.314 ± 0.494
3.942GluVal: 3.942 ± 1.596
1.971GluTrp: 1.971 ± 1.067
2.628GluTyr: 2.628 ± 1.274
0.0GluXaa: 0.0 ± 0.0
Phe
1.971PheAla: 1.971 ± 0.987
0.657PheCys: 0.657 ± 0.489
1.314PheAsp: 1.314 ± 0.494
3.285PheGlu: 3.285 ± 1.234
1.971PhePhe: 1.971 ± 0.149
0.657PheGly: 0.657 ± 0.574
1.314PheHis: 1.314 ± 0.637
1.314PheIle: 1.314 ± 1.154
1.314PheLys: 1.314 ± 0.494
1.971PheLeu: 1.971 ± 0.798
0.0PheMet: 0.0 ± 0.0
1.971PheAsn: 1.971 ± 0.987
0.657PhePro: 0.657 ± 0.577
0.657PheGln: 0.657 ± 0.577
1.314PheArg: 1.314 ± 0.978
3.285PheSer: 3.285 ± 1.661
1.971PheThr: 1.971 ± 1.067
2.628PheVal: 2.628 ± 0.989
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.285GlyAla: 3.285 ± 2.091
0.657GlyCys: 0.657 ± 0.489
2.628GlyAsp: 2.628 ± 0.657
1.314GlyGlu: 1.314 ± 0.494
3.942GlyPhe: 3.942 ± 0.972
3.942GlyGly: 3.942 ± 0.732
0.657GlyHis: 0.657 ± 0.574
2.628GlyIle: 2.628 ± 1.274
7.884GlyLys: 7.884 ± 2.486
3.942GlyLeu: 3.942 ± 1.036
2.628GlyMet: 2.628 ± 0.682
1.314GlyAsn: 1.314 ± 0.637
3.942GlyPro: 3.942 ± 1.483
0.657GlyGln: 0.657 ± 0.577
3.285GlyArg: 3.285 ± 2.141
5.913GlySer: 5.913 ± 0.651
5.256GlyThr: 5.256 ± 2.449
7.227GlyVal: 7.227 ± 1.084
1.314GlyTrp: 1.314 ± 0.523
0.657GlyTyr: 0.657 ± 0.489
0.0GlyXaa: 0.0 ± 0.0
His
0.657HisAla: 0.657 ± 0.574
0.657HisCys: 0.657 ± 0.574
1.314HisAsp: 1.314 ± 0.523
0.657HisGlu: 0.657 ± 0.574
0.657HisPhe: 0.657 ± 0.577
1.971HisGly: 1.971 ± 0.987
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.314HisLys: 1.314 ± 0.523
4.599HisLeu: 4.599 ± 1.135
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.628HisPro: 2.628 ± 1.046
0.657HisGln: 0.657 ± 0.574
1.971HisArg: 1.971 ± 0.149
1.314HisSer: 1.314 ± 0.637
1.314HisThr: 1.314 ± 0.523
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
2.628HisTyr: 2.628 ± 0.657
0.0HisXaa: 0.0 ± 0.0
Ile
2.628IleAla: 2.628 ± 1.274
0.0IleCys: 0.0 ± 0.0
1.971IleAsp: 1.971 ± 1.071
0.657IleGlu: 0.657 ± 0.574
1.971IlePhe: 1.971 ± 0.798
5.256IleGly: 5.256 ± 1.8
0.657IleHis: 0.657 ± 0.577
2.628IleIle: 2.628 ± 0.341
2.628IleLys: 2.628 ± 1.495
3.285IleLeu: 3.285 ± 0.512
1.314IleMet: 1.314 ± 1.149
1.971IleAsn: 1.971 ± 0.832
3.942IlePro: 3.942 ± 1.036
0.657IleGln: 0.657 ± 0.574
3.285IleArg: 3.285 ± 0.448
3.285IleSer: 3.285 ± 0.83
2.628IleThr: 2.628 ± 1.274
2.628IleVal: 2.628 ± 0.657
1.314IleTrp: 1.314 ± 0.523
3.285IleTyr: 3.285 ± 0.448
0.0IleXaa: 0.0 ± 0.0
Lys
8.541LysAla: 8.541 ± 2.001
0.657LysCys: 0.657 ± 0.577
2.628LysAsp: 2.628 ± 1.955
1.971LysGlu: 1.971 ± 0.798
0.0LysPhe: 0.0 ± 0.0
5.256LysGly: 5.256 ± 0.449
1.314LysHis: 1.314 ± 0.637
3.942LysIle: 3.942 ± 1.797
3.285LysLys: 3.285 ± 1.689
6.57LysLeu: 6.57 ± 0.896
3.285LysMet: 3.285 ± 1.689
0.657LysAsn: 0.657 ± 0.489
5.256LysPro: 5.256 ± 2.121
4.599LysGln: 4.599 ± 0.932
6.57LysArg: 6.57 ± 2.472
4.599LysSer: 4.599 ± 2.012
5.256LysThr: 5.256 ± 2.121
5.913LysVal: 5.913 ± 1.171
0.0LysTrp: 0.0 ± 0.0
1.314LysTyr: 1.314 ± 1.149
0.0LysXaa: 0.0 ± 0.0
Leu
7.884LeuAla: 7.884 ± 2.933
1.971LeuCys: 1.971 ± 0.954
5.256LeuAsp: 5.256 ± 1.396
6.57LeuGlu: 6.57 ± 1.584
0.657LeuPhe: 0.657 ± 0.577
9.198LeuGly: 9.198 ± 1.578
1.971LeuHis: 1.971 ± 0.149
3.285LeuIle: 3.285 ± 1.689
5.256LeuLys: 5.256 ± 1.127
4.599LeuLeu: 4.599 ± 2.37
1.971LeuMet: 1.971 ± 0.987
3.285LeuAsn: 3.285 ± 0.512
4.599LeuPro: 4.599 ± 0.197
2.628LeuGln: 2.628 ± 1.261
4.599LeuArg: 4.599 ± 1.024
7.227LeuSer: 7.227 ± 1.165
3.942LeuThr: 3.942 ± 0.732
1.971LeuVal: 1.971 ± 1.466
0.657LeuTrp: 0.657 ± 0.489
1.314LeuTyr: 1.314 ± 0.494
0.0LeuXaa: 0.0 ± 0.0
Met
3.942MetAla: 3.942 ± 0.67
0.0MetCys: 0.0 ± 0.0
0.657MetAsp: 0.657 ± 0.574
1.314MetGlu: 1.314 ± 0.637
0.657MetPhe: 0.657 ± 0.574
1.314MetGly: 1.314 ± 0.523
0.657MetHis: 0.657 ± 0.577
0.657MetIle: 0.657 ± 0.489
1.971MetLys: 1.971 ± 0.832
0.0MetLeu: 0.0 ± 0.0
1.314MetMet: 1.314 ± 0.523
0.657MetAsn: 0.657 ± 0.574
0.657MetPro: 0.657 ± 0.577
1.314MetGln: 1.314 ± 1.149
1.314MetArg: 1.314 ± 0.637
1.971MetSer: 1.971 ± 0.798
1.971MetThr: 1.971 ± 1.071
1.314MetVal: 1.314 ± 1.154
0.657MetTrp: 0.657 ± 0.574
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.942AsnAla: 3.942 ± 0.299
0.0AsnCys: 0.0 ± 0.0
2.628AsnAsp: 2.628 ± 1.274
1.314AsnGlu: 1.314 ± 0.494
0.657AsnPhe: 0.657 ± 0.574
2.628AsnGly: 2.628 ± 1.046
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
1.314AsnLys: 1.314 ± 0.978
3.942AsnLeu: 3.942 ± 0.67
1.971AsnMet: 1.971 ± 1.052
0.657AsnAsn: 0.657 ± 0.574
0.657AsnPro: 0.657 ± 0.489
1.314AsnGln: 1.314 ± 1.154
3.942AsnArg: 3.942 ± 1.036
3.285AsnSer: 3.285 ± 0.512
3.285AsnThr: 3.285 ± 2.141
0.657AsnVal: 0.657 ± 0.574
0.657AsnTrp: 0.657 ± 0.577
1.314AsnTyr: 1.314 ± 1.149
0.0AsnXaa: 0.0 ± 0.0
Pro
3.285ProAla: 3.285 ± 1.301
1.314ProCys: 1.314 ± 0.637
2.628ProAsp: 2.628 ± 1.598
5.256ProGlu: 5.256 ± 0.543
0.0ProPhe: 0.0 ± 0.0
3.285ProGly: 3.285 ± 1.301
1.314ProHis: 1.314 ± 0.978
4.599ProIle: 4.599 ± 0.759
6.57ProLys: 6.57 ± 0.941
4.599ProLeu: 4.599 ± 2.079
0.657ProMet: 0.657 ± 0.489
0.657ProAsn: 0.657 ± 0.489
6.57ProPro: 6.57 ± 3.273
1.314ProGln: 1.314 ± 0.523
2.628ProArg: 2.628 ± 0.989
3.285ProSer: 3.285 ± 0.786
2.628ProThr: 2.628 ± 0.682
7.884ProVal: 7.884 ± 1.376
0.657ProTrp: 0.657 ± 0.577
0.657ProTyr: 0.657 ± 0.574
0.0ProXaa: 0.0 ± 0.0
Gln
3.942GlnAla: 3.942 ± 1.664
0.657GlnCys: 0.657 ± 0.489
0.0GlnAsp: 0.0 ± 0.0
3.285GlnGlu: 3.285 ± 1.255
1.314GlnPhe: 1.314 ± 1.154
1.971GlnGly: 1.971 ± 1.067
0.657GlnHis: 0.657 ± 0.577
0.0GlnIle: 0.0 ± 0.0
1.971GlnLys: 1.971 ± 0.798
1.314GlnLeu: 1.314 ± 0.637
1.314GlnMet: 1.314 ± 1.149
1.314GlnAsn: 1.314 ± 0.978
2.628GlnPro: 2.628 ± 0.682
2.628GlnGln: 2.628 ± 0.341
3.285GlnArg: 3.285 ± 1.721
1.971GlnSer: 1.971 ± 1.071
1.971GlnThr: 1.971 ± 0.798
2.628GlnVal: 2.628 ± 0.341
0.657GlnTrp: 0.657 ± 0.489
0.657GlnTyr: 0.657 ± 0.574
0.0GlnXaa: 0.0 ± 0.0
Arg
3.942ArgAla: 3.942 ± 0.299
0.657ArgCys: 0.657 ± 0.577
3.285ArgAsp: 3.285 ± 1.407
5.913ArgGlu: 5.913 ± 2.913
3.942ArgPhe: 3.942 ± 2.194
1.971ArgGly: 1.971 ± 0.832
1.971ArgHis: 1.971 ± 1.466
0.0ArgIle: 0.0 ± 0.0
3.285ArgLys: 3.285 ± 1.689
7.884ArgLeu: 7.884 ± 2.933
1.971ArgMet: 1.971 ± 1.067
1.314ArgAsn: 1.314 ± 1.149
2.628ArgPro: 2.628 ± 0.989
5.256ArgGln: 5.256 ± 1.587
7.884ArgArg: 7.884 ± 2.263
6.57ArgSer: 6.57 ± 0.876
1.314ArgThr: 1.314 ± 0.494
5.256ArgVal: 5.256 ± 1.127
2.628ArgTrp: 2.628 ± 1.261
2.628ArgTyr: 2.628 ± 0.657
0.0ArgXaa: 0.0 ± 0.0
Ser
3.942SerAla: 3.942 ± 1.974
0.657SerCys: 0.657 ± 0.489
3.942SerAsp: 3.942 ± 1.036
2.628SerGlu: 2.628 ± 1.046
2.628SerPhe: 2.628 ± 0.989
3.942SerGly: 3.942 ± 1.318
0.657SerHis: 0.657 ± 0.489
4.599SerIle: 4.599 ± 2.509
5.913SerLys: 5.913 ± 1.921
5.256SerLeu: 5.256 ± 1.313
0.657SerMet: 0.657 ± 0.636
1.314SerAsn: 1.314 ± 0.978
3.942SerPro: 3.942 ± 1.83
3.285SerGln: 3.285 ± 1.255
3.285SerArg: 3.285 ± 0.83
7.884SerSer: 7.884 ± 3.66
7.227SerThr: 7.227 ± 2.399
6.57SerVal: 6.57 ± 1.674
3.942SerTrp: 3.942 ± 0.972
2.628SerTyr: 2.628 ± 1.495
0.0SerXaa: 0.0 ± 0.0
Thr
7.884ThrAla: 7.884 ± 2.071
1.971ThrCys: 1.971 ± 0.987
1.971ThrAsp: 1.971 ± 1.466
1.971ThrGlu: 1.971 ± 1.067
1.314ThrPhe: 1.314 ± 0.637
3.942ThrGly: 3.942 ± 2.713
1.314ThrHis: 1.314 ± 0.523
4.599ThrIle: 4.599 ± 0.932
3.942ThrLys: 3.942 ± 1.196
3.942ThrLeu: 3.942 ± 1.318
0.657ThrMet: 0.657 ± 0.574
3.942ThrAsn: 3.942 ± 1.911
4.599ThrPro: 4.599 ± 0.759
0.657ThrGln: 0.657 ± 0.577
0.657ThrArg: 0.657 ± 0.489
4.599ThrSer: 4.599 ± 0.197
3.285ThrThr: 3.285 ± 2.151
6.57ThrVal: 6.57 ± 0.941
0.657ThrTrp: 0.657 ± 0.577
3.285ThrTyr: 3.285 ± 0.786
0.0ThrXaa: 0.0 ± 0.0
Val
9.855ValAla: 9.855 ± 2.291
1.314ValCys: 1.314 ± 0.637
2.628ValAsp: 2.628 ± 1.495
6.57ValGlu: 6.57 ± 2.814
0.657ValPhe: 0.657 ± 0.574
2.628ValGly: 2.628 ± 1.261
3.285ValHis: 3.285 ± 1.225
4.599ValIle: 4.599 ± 0.932
5.913ValLys: 5.913 ± 0.651
3.285ValLeu: 3.285 ± 1.301
0.0ValMet: 0.0 ± 0.0
0.657ValAsn: 0.657 ± 0.577
3.942ValPro: 3.942 ± 2.163
0.0ValGln: 0.0 ± 0.0
4.599ValArg: 4.599 ± 1.703
5.913ValSer: 5.913 ± 3.618
7.227ValThr: 7.227 ± 1.9
7.227ValVal: 7.227 ± 0.498
0.0ValTrp: 0.0 ± 0.0
1.971ValTyr: 1.971 ± 1.071
0.0ValXaa: 0.0 ± 0.0
Trp
1.971TrpAla: 1.971 ± 0.987
0.657TrpCys: 0.657 ± 0.574
1.971TrpAsp: 1.971 ± 0.149
0.0TrpGlu: 0.0 ± 0.0
0.657TrpPhe: 0.657 ± 0.577
0.657TrpGly: 0.657 ± 0.489
0.657TrpHis: 0.657 ± 0.577
0.0TrpIle: 0.0 ± 0.0
0.657TrpLys: 0.657 ± 0.574
1.971TrpLeu: 1.971 ± 0.954
0.0TrpMet: 0.0 ± 0.0
2.628TrpAsn: 2.628 ± 0.682
0.657TrpPro: 0.657 ± 0.489
0.0TrpGln: 0.0 ± 0.0
1.971TrpArg: 1.971 ± 0.832
1.971TrpSer: 1.971 ± 0.149
0.0TrpThr: 0.0 ± 0.0
1.314TrpVal: 1.314 ± 0.978
0.0TrpTrp: 0.0 ± 0.0
1.971TrpTyr: 1.971 ± 0.832
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.628TyrAla: 2.628 ± 0.682
2.628TyrCys: 2.628 ± 2.298
1.314TyrAsp: 1.314 ± 1.149
1.971TyrGlu: 1.971 ± 1.067
0.657TyrPhe: 0.657 ± 0.577
1.971TyrGly: 1.971 ± 1.067
0.657TyrHis: 0.657 ± 0.574
3.285TyrIle: 3.285 ± 0.448
1.314TyrLys: 1.314 ± 0.494
1.971TyrLeu: 1.971 ± 0.954
1.314TyrMet: 1.314 ± 1.154
2.628TyrAsn: 2.628 ± 1.591
1.314TyrPro: 1.314 ± 1.154
0.657TyrGln: 0.657 ± 0.489
3.942TyrArg: 3.942 ± 1.596
1.314TyrSer: 1.314 ± 1.149
1.314TyrThr: 1.314 ± 0.494
0.657TyrVal: 0.657 ± 0.574
0.0TyrTrp: 0.0 ± 0.0
0.657TyrTyr: 0.657 ± 0.574
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1523 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski