Amino acid dipepetide frequency for Pelargonium zonate spot virus (isolate Tomato/Italy/1982) (PZSV) (Pelargonium zonate spot virus (isolate Tomato))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.309AlaAla: 2.309 ± 0.825
0.462AlaCys: 0.462 ± 0.384
5.081AlaAsp: 5.081 ± 0.461
4.619AlaGlu: 4.619 ± 1.436
2.309AlaPhe: 2.309 ± 0.483
5.081AlaGly: 5.081 ± 1.248
3.233AlaHis: 3.233 ± 0.313
4.619AlaIle: 4.619 ± 0.498
2.309AlaLys: 2.309 ± 1.829
6.467AlaLeu: 6.467 ± 4.146
3.233AlaMet: 3.233 ± 1.793
1.848AlaAsn: 1.848 ± 0.83
2.771AlaPro: 2.771 ± 0.524
0.462AlaGln: 0.462 ± 0.332
5.081AlaArg: 5.081 ± 2.074
2.771AlaSer: 2.771 ± 0.948
3.695AlaThr: 3.695 ± 2.962
4.157AlaVal: 4.157 ± 1.441
0.0AlaTrp: 0.0 ± 0.0
1.848AlaTyr: 1.848 ± 0.993
0.0AlaXaa: 0.0 ± 0.0
Cys
2.309CysAla: 2.309 ± 0.82
0.924CysCys: 0.924 ± 0.664
2.771CysAsp: 2.771 ± 1.292
1.848CysGlu: 1.848 ± 1.328
0.924CysPhe: 0.924 ± 0.328
1.386CysGly: 1.386 ± 0.996
0.462CysHis: 0.462 ± 0.332
0.462CysIle: 0.462 ± 0.634
0.924CysLys: 0.924 ± 0.328
1.848CysLeu: 1.848 ± 0.437
0.462CysMet: 0.462 ± 0.333
0.462CysAsn: 0.462 ± 0.634
2.309CysPro: 2.309 ± 1.145
0.462CysGln: 0.462 ± 0.634
0.462CysArg: 0.462 ± 0.332
2.309CysSer: 2.309 ± 1.918
0.0CysThr: 0.0 ± 0.0
3.233CysVal: 3.233 ± 1.207
0.462CysTrp: 0.462 ± 0.384
0.462CysTyr: 0.462 ± 0.384
0.0CysXaa: 0.0 ± 0.0
Asp
4.619AspAla: 4.619 ± 1.256
1.386AspCys: 1.386 ± 0.666
3.695AspAsp: 3.695 ± 2.505
4.619AspGlu: 4.619 ± 1.862
3.695AspPhe: 3.695 ± 0.771
2.309AspGly: 2.309 ± 1.145
0.0AspHis: 0.0 ± 0.0
1.848AspIle: 1.848 ± 0.634
4.157AspLys: 4.157 ± 1.454
5.543AspLeu: 5.543 ± 1.339
3.233AspMet: 3.233 ± 1.539
2.309AspAsn: 2.309 ± 1.527
5.081AspPro: 5.081 ± 1.803
0.462AspGln: 0.462 ± 0.332
3.233AspArg: 3.233 ± 1.295
4.619AspSer: 4.619 ± 1.651
3.233AspThr: 3.233 ± 1.619
6.467AspVal: 6.467 ± 2.295
0.0AspTrp: 0.0 ± 0.0
4.157AspTyr: 4.157 ± 1.332
0.0AspXaa: 0.0 ± 0.0
Glu
3.233GluAla: 3.233 ± 0.693
0.924GluCys: 0.924 ± 0.664
5.543GluAsp: 5.543 ± 1.141
5.543GluGlu: 5.543 ± 2.173
3.233GluPhe: 3.233 ± 1.295
2.771GluGly: 2.771 ± 0.581
1.848GluHis: 1.848 ± 1.694
0.924GluIle: 0.924 ± 0.328
5.543GluLys: 5.543 ± 0.283
4.157GluLeu: 4.157 ± 1.314
1.386GluMet: 1.386 ± 0.889
1.386GluAsn: 1.386 ± 0.458
0.462GluPro: 0.462 ± 0.332
2.771GluGln: 2.771 ± 0.534
5.543GluArg: 5.543 ± 0.904
6.467GluSer: 6.467 ± 2.017
2.771GluThr: 2.771 ± 0.581
8.314GluVal: 8.314 ± 0.983
0.924GluTrp: 0.924 ± 0.328
2.771GluTyr: 2.771 ± 0.581
0.0GluXaa: 0.0 ± 0.0
Phe
3.233PheAla: 3.233 ± 1.311
1.386PheCys: 1.386 ± 0.632
5.543PheAsp: 5.543 ± 1.351
4.157PheGlu: 4.157 ± 1.611
2.309PhePhe: 2.309 ± 1.099
5.081PheGly: 5.081 ± 1.873
1.386PheHis: 1.386 ± 0.632
1.386PheIle: 1.386 ± 0.458
2.771PheLys: 2.771 ± 0.755
3.233PheLeu: 3.233 ± 1.096
0.462PheMet: 0.462 ± 0.488
2.309PheAsn: 2.309 ± 0.931
2.771PhePro: 2.771 ± 1.102
1.848PheGln: 1.848 ± 1.535
4.619PheArg: 4.619 ± 1.225
3.233PheSer: 3.233 ± 1.691
4.157PheThr: 4.157 ± 1.332
3.695PheVal: 3.695 ± 0.827
0.462PheTrp: 0.462 ± 0.837
0.462PheTyr: 0.462 ± 0.384
0.0PheXaa: 0.0 ± 0.0
Gly
5.543GlyAla: 5.543 ± 1.068
2.309GlyCys: 2.309 ± 0.627
3.695GlyAsp: 3.695 ± 0.827
3.233GlyGlu: 3.233 ± 1.059
3.695GlyPhe: 3.695 ± 1.564
3.695GlyGly: 3.695 ± 1.783
0.462GlyHis: 0.462 ± 0.837
2.309GlyIle: 2.309 ± 1.184
4.619GlyLys: 4.619 ± 1.079
5.543GlyLeu: 5.543 ± 0.746
0.924GlyMet: 0.924 ± 0.664
2.771GlyAsn: 2.771 ± 0.524
1.386GlyPro: 1.386 ± 0.458
1.386GlyGln: 1.386 ± 0.919
3.233GlyArg: 3.233 ± 0.313
2.771GlySer: 2.771 ± 1.063
4.619GlyThr: 4.619 ± 1.443
4.157GlyVal: 4.157 ± 1.029
0.924GlyTrp: 0.924 ± 0.664
1.848GlyTyr: 1.848 ± 0.892
0.0GlyXaa: 0.0 ± 0.0
His
0.924HisAla: 0.924 ± 0.328
0.924HisCys: 0.924 ± 0.664
0.0HisAsp: 0.0 ± 0.0
1.386HisGlu: 1.386 ± 0.67
1.386HisPhe: 1.386 ± 0.996
1.848HisGly: 1.848 ± 0.83
0.462HisHis: 0.462 ± 0.332
0.462HisIle: 0.462 ± 0.634
2.309HisLys: 2.309 ± 1.245
2.309HisLeu: 2.309 ± 1.534
0.924HisMet: 0.924 ± 0.767
0.924HisAsn: 0.924 ± 0.328
0.0HisPro: 0.0 ± 0.0
2.309HisGln: 2.309 ± 0.483
0.462HisArg: 0.462 ± 0.332
2.309HisSer: 2.309 ± 1.145
1.386HisThr: 1.386 ± 0.919
1.848HisVal: 1.848 ± 0.782
0.462HisTrp: 0.462 ± 0.332
1.386HisTyr: 1.386 ± 0.67
0.0HisXaa: 0.0 ± 0.0
Ile
0.462IleAla: 0.462 ± 0.384
1.386IleCys: 1.386 ± 0.632
2.771IleAsp: 2.771 ± 0.755
2.309IleGlu: 2.309 ± 0.483
1.386IlePhe: 1.386 ± 0.67
3.233IleGly: 3.233 ± 0.313
0.924IleHis: 0.924 ± 0.559
0.462IleIle: 0.462 ± 0.332
2.771IleLys: 2.771 ± 1.467
2.771IleLeu: 2.771 ± 1.467
2.771IleMet: 2.771 ± 1.467
2.309IleAsn: 2.309 ± 1.145
2.771IlePro: 2.771 ± 1.531
0.924IleGln: 0.924 ± 0.328
3.233IleArg: 3.233 ± 1.096
6.928IleSer: 6.928 ± 1.328
1.386IleThr: 1.386 ± 1.64
3.233IleVal: 3.233 ± 0.97
0.462IleTrp: 0.462 ± 0.332
0.462IleTyr: 0.462 ± 0.837
0.0IleXaa: 0.0 ± 0.0
Lys
5.081LysAla: 5.081 ± 2.112
1.386LysCys: 1.386 ± 0.537
2.771LysAsp: 2.771 ± 0.984
3.695LysGlu: 3.695 ± 0.874
3.695LysPhe: 3.695 ± 1.02
2.771LysGly: 2.771 ± 1.24
0.0LysHis: 0.0 ± 0.0
6.005LysIle: 6.005 ± 1.583
2.771LysLys: 2.771 ± 0.984
4.157LysLeu: 4.157 ± 2.042
2.309LysMet: 2.309 ± 0.825
2.309LysAsn: 2.309 ± 1.145
2.309LysPro: 2.309 ± 1.535
1.386LysGln: 1.386 ± 1.247
4.619LysArg: 4.619 ± 0.944
6.005LysSer: 6.005 ± 1.347
4.157LysThr: 4.157 ± 0.71
5.543LysVal: 5.543 ± 2.354
0.924LysTrp: 0.924 ± 0.67
1.848LysTyr: 1.848 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
4.619LeuAla: 4.619 ± 2.057
2.309LeuCys: 2.309 ± 1.145
6.467LeuAsp: 6.467 ± 0.92
4.619LeuGlu: 4.619 ± 1.256
6.928LeuPhe: 6.928 ± 1.089
4.619LeuGly: 4.619 ± 1.3
1.386LeuHis: 1.386 ± 0.458
4.619LeuIle: 4.619 ± 1.244
6.005LeuLys: 6.005 ± 0.867
6.005LeuLeu: 6.005 ± 0.851
3.233LeuMet: 3.233 ± 0.324
4.157LeuAsn: 4.157 ± 1.554
3.695LeuPro: 3.695 ± 2.408
2.309LeuGln: 2.309 ± 0.483
5.543LeuArg: 5.543 ± 1.641
7.39LeuSer: 7.39 ± 0.702
3.233LeuThr: 3.233 ± 1.569
6.928LeuVal: 6.928 ± 1.897
1.848LeuTrp: 1.848 ± 0.83
0.924LeuTyr: 0.924 ± 0.559
0.0LeuXaa: 0.0 ± 0.0
Met
2.771MetAla: 2.771 ± 1.074
0.0MetCys: 0.0 ± 0.0
1.386MetAsp: 1.386 ± 0.632
1.848MetGlu: 1.848 ± 0.656
3.233MetPhe: 3.233 ± 0.687
2.309MetGly: 2.309 ± 0.627
1.848MetHis: 1.848 ± 0.437
0.924MetIle: 0.924 ± 0.328
1.386MetLys: 1.386 ± 0.666
3.233MetLeu: 3.233 ± 0.687
0.924MetMet: 0.924 ± 0.664
0.924MetAsn: 0.924 ± 0.328
1.386MetPro: 1.386 ± 1.558
1.386MetGln: 1.386 ± 0.537
2.771MetArg: 2.771 ± 0.916
2.771MetSer: 2.771 ± 0.581
1.386MetThr: 1.386 ± 0.996
0.924MetVal: 0.924 ± 0.664
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.848AsnAla: 1.848 ± 1.498
1.386AsnCys: 1.386 ± 0.458
1.386AsnAsp: 1.386 ± 0.632
3.233AsnGlu: 3.233 ± 1.059
1.848AsnPhe: 1.848 ± 1.535
1.848AsnGly: 1.848 ± 0.892
0.0AsnHis: 0.0 ± 0.0
1.848AsnIle: 1.848 ± 0.83
2.309AsnLys: 2.309 ± 0.825
4.619AsnLeu: 4.619 ± 1.071
1.386AsnMet: 1.386 ± 0.632
2.771AsnAsn: 2.771 ± 1.102
0.462AsnPro: 0.462 ± 0.332
0.462AsnGln: 0.462 ± 0.634
0.924AsnArg: 0.924 ± 1.675
2.771AsnSer: 2.771 ± 1.24
2.771AsnThr: 2.771 ± 0.66
2.309AsnVal: 2.309 ± 1.145
0.924AsnTrp: 0.924 ± 0.328
0.462AsnTyr: 0.462 ± 0.634
0.0AsnXaa: 0.0 ± 0.0
Pro
2.771ProAla: 2.771 ± 0.534
0.924ProCys: 0.924 ± 0.328
4.157ProAsp: 4.157 ± 0.64
1.848ProGlu: 1.848 ± 0.781
0.462ProPhe: 0.462 ± 0.384
2.771ProGly: 2.771 ± 1.855
0.924ProHis: 0.924 ± 0.664
2.309ProIle: 2.309 ± 1.535
3.695ProLys: 3.695 ± 0.972
3.233ProLeu: 3.233 ± 0.97
0.462ProMet: 0.462 ± 0.384
1.386ProAsn: 1.386 ± 0.828
1.386ProPro: 1.386 ± 0.67
0.462ProGln: 0.462 ± 0.634
1.386ProArg: 1.386 ± 0.458
7.852ProSer: 7.852 ± 2.908
1.386ProThr: 1.386 ± 0.67
3.695ProVal: 3.695 ± 1.531
0.0ProTrp: 0.0 ± 0.0
1.848ProTyr: 1.848 ± 0.656
0.0ProXaa: 0.0 ± 0.0
Gln
2.771GlnAla: 2.771 ± 1.532
0.462GlnCys: 0.462 ± 0.332
0.0GlnAsp: 0.0 ± 0.0
1.848GlnGlu: 1.848 ± 1.118
1.386GlnPhe: 1.386 ± 0.632
1.848GlnGly: 1.848 ± 0.634
0.462GlnHis: 0.462 ± 0.332
1.848GlnIle: 1.848 ± 1.328
2.771GlnLys: 2.771 ± 0.984
2.309GlnLeu: 2.309 ± 0.947
0.0GlnMet: 0.0 ± 0.0
0.924GlnAsn: 0.924 ± 1.675
0.924GlnPro: 0.924 ± 0.328
1.386GlnGln: 1.386 ± 0.67
3.233GlnArg: 3.233 ± 1.619
3.233GlnSer: 3.233 ± 1.5
0.0GlnThr: 0.0 ± 0.0
0.462GlnVal: 0.462 ± 0.634
0.0GlnTrp: 0.0 ± 0.0
1.848GlnTyr: 1.848 ± 0.634
0.0GlnXaa: 0.0 ± 0.0
Arg
3.233ArgAla: 3.233 ± 1.295
2.309ArgCys: 2.309 ± 0.825
5.543ArgAsp: 5.543 ± 1.471
2.771ArgGlu: 2.771 ± 1.392
1.386ArgPhe: 1.386 ± 0.996
2.771ArgGly: 2.771 ± 1.469
0.924ArgHis: 0.924 ± 0.664
2.309ArgIle: 2.309 ± 0.603
3.695ArgLys: 3.695 ± 0.827
6.005ArgLeu: 6.005 ± 0.815
1.386ArgMet: 1.386 ± 0.458
1.848ArgAsn: 1.848 ± 0.993
3.233ArgPro: 3.233 ± 1.781
4.157ArgGln: 4.157 ± 1.984
4.157ArgArg: 4.157 ± 1.952
2.309ArgSer: 2.309 ± 2.473
3.233ArgThr: 3.233 ± 0.832
3.695ArgVal: 3.695 ± 1.339
1.848ArgTrp: 1.848 ± 0.782
2.309ArgTyr: 2.309 ± 0.825
0.0ArgXaa: 0.0 ± 0.0
Ser
4.619SerAla: 4.619 ± 1.895
0.924SerCys: 0.924 ± 0.328
5.543SerAsp: 5.543 ± 1.363
6.005SerGlu: 6.005 ± 1.183
6.928SerPhe: 6.928 ± 1.089
5.543SerGly: 5.543 ± 0.283
3.233SerHis: 3.233 ± 0.832
1.848SerIle: 1.848 ± 0.437
5.543SerLys: 5.543 ± 1.312
12.471SerLeu: 12.471 ± 1.612
1.386SerMet: 1.386 ± 0.67
2.309SerAsn: 2.309 ± 0.933
4.157SerPro: 4.157 ± 1.984
1.386SerGln: 1.386 ± 0.458
2.771SerArg: 2.771 ± 1.34
5.081SerSer: 5.081 ± 1.887
5.543SerThr: 5.543 ± 2.537
6.005SerVal: 6.005 ± 0.798
1.386SerTrp: 1.386 ± 0.828
2.309SerTyr: 2.309 ± 0.947
0.0SerXaa: 0.0 ± 0.0
Thr
3.233ThrAla: 3.233 ± 1.298
1.386ThrCys: 1.386 ± 0.458
2.309ThrAsp: 2.309 ± 0.642
4.157ThrGlu: 4.157 ± 2.262
3.695ThrPhe: 3.695 ± 1.271
2.771ThrGly: 2.771 ± 2.077
1.848ThrHis: 1.848 ± 0.634
4.157ThrIle: 4.157 ± 1.454
2.309ThrLys: 2.309 ± 0.627
2.771ThrLeu: 2.771 ± 0.534
2.771ThrMet: 2.771 ± 0.948
0.0ThrAsn: 0.0 ± 0.0
1.386ThrPro: 1.386 ± 0.632
1.848ThrGln: 1.848 ± 0.437
1.848ThrArg: 1.848 ± 0.634
5.543ThrSer: 5.543 ± 1.737
4.157ThrThr: 4.157 ± 2.053
5.081ThrVal: 5.081 ± 2.698
0.462ThrTrp: 0.462 ± 0.384
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.928ValAla: 6.928 ± 1.457
2.771ValCys: 2.771 ± 1.778
2.771ValAsp: 2.771 ± 1.264
6.005ValGlu: 6.005 ± 2.561
2.771ValPhe: 2.771 ± 0.903
5.081ValGly: 5.081 ± 1.336
1.848ValHis: 1.848 ± 1.328
3.233ValIle: 3.233 ± 0.768
5.081ValLys: 5.081 ± 1.914
6.467ValLeu: 6.467 ± 2.243
2.309ValMet: 2.309 ± 0.483
3.233ValAsn: 3.233 ± 1.207
5.543ValPro: 5.543 ± 2.48
0.924ValGln: 0.924 ± 0.664
5.543ValArg: 5.543 ± 2.28
7.852ValSer: 7.852 ± 1.669
3.233ValThr: 3.233 ± 0.824
4.157ValVal: 4.157 ± 1.47
1.386ValTrp: 1.386 ± 0.666
0.462ValTyr: 0.462 ± 0.837
0.0ValXaa: 0.0 ± 0.0
Trp
0.462TrpAla: 0.462 ± 0.837
1.386TrpCys: 1.386 ± 1.039
0.462TrpAsp: 0.462 ± 0.634
0.462TrpGlu: 0.462 ± 0.384
0.924TrpPhe: 0.924 ± 0.664
0.462TrpGly: 0.462 ± 0.384
0.462TrpHis: 0.462 ± 0.384
0.0TrpIle: 0.0 ± 0.0
1.386TrpLys: 1.386 ± 0.666
1.386TrpLeu: 1.386 ± 0.537
0.0TrpMet: 0.0 ± 0.0
0.462TrpAsn: 0.462 ± 0.384
0.462TrpPro: 0.462 ± 0.332
0.462TrpGln: 0.462 ± 0.332
0.462TrpArg: 0.462 ± 0.332
0.924TrpSer: 0.924 ± 0.664
0.924TrpThr: 0.924 ± 0.328
1.386TrpVal: 1.386 ± 0.828
0.462TrpTrp: 0.462 ± 0.384
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.386TyrAla: 1.386 ± 0.919
0.0TyrCys: 0.0 ± 0.0
2.771TyrAsp: 2.771 ± 0.755
2.309TyrGlu: 2.309 ± 1.527
2.309TyrPhe: 2.309 ± 1.366
0.924TyrGly: 0.924 ± 0.664
2.309TyrHis: 2.309 ± 0.758
1.386TyrIle: 1.386 ± 0.67
1.386TyrLys: 1.386 ± 0.632
2.309TyrLeu: 2.309 ± 0.603
1.386TyrMet: 1.386 ± 0.458
0.924TyrAsn: 0.924 ± 0.664
0.462TyrPro: 0.462 ± 0.837
0.924TyrGln: 0.924 ± 0.328
0.0TyrArg: 0.0 ± 0.0
1.848TyrSer: 1.848 ± 0.437
0.462TyrThr: 0.462 ± 0.384
2.309TyrVal: 2.309 ± 0.483
0.0TyrTrp: 0.0 ± 0.0
1.386TyrTyr: 1.386 ± 0.632
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2166 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski