Amino acid dipepetide frequency for Lachnotalea glycerini

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.269AlaAla: 5.269 ± 0.08	0.98AlaCys: 0.98 ± 0.024	3.442AlaAsp: 3.442 ± 0.055	3.638AlaGlu: 3.638 ± 0.059	2.808AlaPhe: 2.808 ± 0.049	4.746AlaGly: 4.746 ± 0.074	0.884AlaHis: 0.884 ± 0.026	5.773AlaIle: 5.773 ± 0.072	4.821AlaLys: 4.821 ± 0.064	5.975AlaLeu: 5.975 ± 0.083	2.02AlaMet: 2.02 ± 0.036	3.077AlaAsn: 3.077 ± 0.043	1.487AlaPro: 1.487 ± 0.039	1.944AlaGln: 1.944 ± 0.036	2.116AlaArg: 2.116 ± 0.04	3.99AlaSer: 3.99 ± 0.062	3.343AlaThr: 3.343 ± 0.055	4.757AlaVal: 4.757 ± 0.072	0.517AlaTrp: 0.517 ± 0.021	2.657AlaTyr: 2.657 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.818CysAla: 0.818 ± 0.023	0.241CysCys: 0.241 ± 0.014	0.785CysAsp: 0.785 ± 0.024	0.878CysGlu: 0.878 ± 0.029	0.676CysPhe: 0.676 ± 0.022	1.175CysGly: 1.175 ± 0.034	0.278CysHis: 0.278 ± 0.012	1.357CysIle: 1.357 ± 0.04	1.042CysLys: 1.042 ± 0.028	1.064CysLeu: 1.064 ± 0.03	0.433CysMet: 0.433 ± 0.018	0.76CysAsn: 0.76 ± 0.024	0.486CysPro: 0.486 ± 0.021	0.357CysGln: 0.357 ± 0.014	0.468CysArg: 0.468 ± 0.018	0.903CysSer: 0.903 ± 0.027	0.637CysThr: 0.637 ± 0.022	0.882CysVal: 0.882 ± 0.026	0.106CysTrp: 0.106 ± 0.01	0.571CysTyr: 0.571 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	3.286AspAla: 3.286 ± 0.05	0.792AspCys: 0.792 ± 0.025	2.569AspAsp: 2.569 ± 0.04	4.365AspGlu: 4.365 ± 0.045	2.61AspPhe: 2.61 ± 0.038	3.499AspGly: 3.499 ± 0.056	0.714AspHis: 0.714 ± 0.024	5.236AspIle: 5.236 ± 0.062	4.264AspLys: 4.264 ± 0.064	4.299AspLeu: 4.299 ± 0.064	1.661AspMet: 1.661 ± 0.037	2.876AspAsn: 2.876 ± 0.051	1.193AspPro: 1.193 ± 0.035	1.334AspGln: 1.334 ± 0.035	1.719AspArg: 1.719 ± 0.037	3.538AspSer: 3.538 ± 0.053	3.118AspThr: 3.118 ± 0.054	3.258AspVal: 3.258 ± 0.053	0.583AspTrp: 0.583 ± 0.021	2.939AspTyr: 2.939 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	4.739GluAla: 4.739 ± 0.072	0.841GluCys: 0.841 ± 0.023	3.887GluAsp: 3.887 ± 0.057	6.719GluGlu: 6.719 ± 0.084	2.805GluPhe: 2.805 ± 0.046	3.535GluGly: 3.535 ± 0.051	1.181GluHis: 1.181 ± 0.03	6.474GluIle: 6.474 ± 0.063	6.271GluLys: 6.271 ± 0.08	6.734GluLeu: 6.734 ± 0.077	2.208GluMet: 2.208 ± 0.036	4.606GluAsn: 4.606 ± 0.063	1.586GluPro: 1.586 ± 0.032	2.721GluGln: 2.721 ± 0.051	2.668GluArg: 2.668 ± 0.048	3.811GluSer: 3.811 ± 0.059	3.538GluThr: 3.538 ± 0.053	4.31GluVal: 4.31 ± 0.056	0.624GluTrp: 0.624 ± 0.025	3.31GluTyr: 3.31 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.597PheAla: 2.597 ± 0.045	0.702PheCys: 0.702 ± 0.021	2.585PheAsp: 2.585 ± 0.04	2.78PheGlu: 2.78 ± 0.043	1.887PhePhe: 1.887 ± 0.042	2.816PheGly: 2.816 ± 0.048	0.801PheHis: 0.801 ± 0.027	3.987PheIle: 3.987 ± 0.06	2.646PheLys: 2.646 ± 0.046	3.836PheLeu: 3.836 ± 0.067	1.322PheMet: 1.322 ± 0.033	2.143PheAsn: 2.143 ± 0.039	1.148PhePro: 1.148 ± 0.032	1.446PheGln: 1.446 ± 0.033	1.322PheArg: 1.322 ± 0.031	2.982PheSer: 2.982 ± 0.046	2.505PheThr: 2.505 ± 0.038	2.801PheVal: 2.801 ± 0.048	0.436PheTrp: 0.436 ± 0.019	1.979PheTyr: 1.979 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.174GlyAla: 4.174 ± 0.073	1.123GlyCys: 1.123 ± 0.029	3.036GlyAsp: 3.036 ± 0.054	4.096GlyGlu: 4.096 ± 0.058	3.082GlyPhe: 3.082 ± 0.048	4.145GlyGly: 4.145 ± 0.084	1.044GlyHis: 1.044 ± 0.027	6.581GlyIle: 6.581 ± 0.075	4.983GlyLys: 4.983 ± 0.063	5.262GlyLeu: 5.262 ± 0.066	2.064GlyMet: 2.064 ± 0.039	3.296GlyAsn: 3.296 ± 0.051	1.025GlyPro: 1.025 ± 0.029	1.711GlyGln: 1.711 ± 0.037	2.061GlyArg: 2.061 ± 0.041	3.768GlySer: 3.768 ± 0.054	3.77GlyThr: 3.77 ± 0.066	4.307GlyVal: 4.307 ± 0.056	0.56GlyTrp: 0.56 ± 0.018	3.132GlyTyr: 3.132 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	0.906HisAla: 0.906 ± 0.024	0.249HisCys: 0.249 ± 0.014	0.814HisAsp: 0.814 ± 0.028	0.977HisGlu: 0.977 ± 0.03	0.808HisPhe: 0.808 ± 0.022	1.027HisGly: 1.027 ± 0.027	0.312HisHis: 0.312 ± 0.016	1.509HisIle: 1.509 ± 0.035	1.056HisLys: 1.056 ± 0.027	1.353HisLeu: 1.353 ± 0.031	0.494HisMet: 0.494 ± 0.019	0.892HisAsn: 0.892 ± 0.027	0.66HisPro: 0.66 ± 0.021	0.48HisGln: 0.48 ± 0.019	0.541HisArg: 0.541 ± 0.022	0.944HisSer: 0.944 ± 0.027	0.83HisThr: 0.83 ± 0.026	0.887HisVal: 0.887 ± 0.027	0.137HisTrp: 0.137 ± 0.01	0.788HisTyr: 0.788 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.026IleAla: 6.026 ± 0.076	1.431IleCys: 1.431 ± 0.033	4.992IleAsp: 4.992 ± 0.056	6.437IleGlu: 6.437 ± 0.064	3.726IlePhe: 3.726 ± 0.061	5.78IleGly: 5.78 ± 0.079	1.5IleHis: 1.5 ± 0.035	7.975IleIle: 7.975 ± 0.108	6.494IleLys: 6.494 ± 0.07	8.477IleLeu: 8.477 ± 0.098	2.465IleMet: 2.465 ± 0.046	4.882IleAsn: 4.882 ± 0.06	3.272IlePro: 3.272 ± 0.043	2.88IleGln: 2.88 ± 0.046	3.207IleArg: 3.207 ± 0.056	6.322IleSer: 6.322 ± 0.074	5.234IleThr: 5.234 ± 0.061	5.768IleVal: 5.768 ± 0.075	0.647IleTrp: 0.647 ± 0.023	3.726IleTyr: 3.726 ± 0.055	0.0IleXaa: 0.0 ± 0.0
Lys	4.959LysAla: 4.959 ± 0.063	0.785LysCys: 0.785 ± 0.026	4.243LysAsp: 4.243 ± 0.057	7.435LysGlu: 7.435 ± 0.088	2.35LysPhe: 2.35 ± 0.039	4.254LysGly: 4.254 ± 0.058	1.058LysHis: 1.058 ± 0.031	6.59LysIle: 6.59 ± 0.075	6.749LysLys: 6.749 ± 0.076	6.5LysLeu: 6.5 ± 0.071	2.313LysMet: 2.313 ± 0.041	4.802LysAsn: 4.802 ± 0.062	1.909LysPro: 1.909 ± 0.037	2.892LysGln: 2.892 ± 0.05	2.973LysArg: 2.973 ± 0.05	4.265LysSer: 4.265 ± 0.059	4.016LysThr: 4.016 ± 0.059	4.64LysVal: 4.64 ± 0.063	0.63LysTrp: 0.63 ± 0.019	3.391LysTyr: 3.391 ± 0.047	0.0LysXaa: 0.0 ± 0.0
Leu	5.919LeuAla: 5.919 ± 0.081	1.292LeuCys: 1.292 ± 0.034	4.888LeuAsp: 4.888 ± 0.06	6.293LeuGlu: 6.293 ± 0.065	4.027LeuPhe: 4.027 ± 0.078	5.497LeuGly: 5.497 ± 0.066	1.393LeuHis: 1.393 ± 0.029	7.606LeuIle: 7.606 ± 0.083	6.915LeuLys: 6.915 ± 0.075	8.422LeuLeu: 8.422 ± 0.098	2.544LeuMet: 2.544 ± 0.05	5.032LeuAsn: 5.032 ± 0.068	2.974LeuPro: 2.974 ± 0.049	2.744LeuGln: 2.744 ± 0.043	2.925LeuArg: 2.925 ± 0.053	6.829LeuSer: 6.829 ± 0.066	4.943LeuThr: 4.943 ± 0.061	5.222LeuVal: 5.222 ± 0.066	0.702LeuTrp: 0.702 ± 0.025	3.623LeuTyr: 3.623 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	1.942MetAla: 1.942 ± 0.04	0.346MetCys: 0.346 ± 0.014	1.609MetAsp: 1.609 ± 0.035	2.184MetGlu: 2.184 ± 0.043	1.022MetPhe: 1.022 ± 0.027	1.865MetGly: 1.865 ± 0.041	0.445MetHis: 0.445 ± 0.017	2.598MetIle: 2.598 ± 0.051	2.603MetLys: 2.603 ± 0.048	2.818MetLeu: 2.818 ± 0.047	0.822MetMet: 0.822 ± 0.026	1.835MetAsn: 1.835 ± 0.04	0.987MetPro: 0.987 ± 0.027	1.048MetGln: 1.048 ± 0.032	0.944MetArg: 0.944 ± 0.024	1.883MetSer: 1.883 ± 0.034	1.566MetThr: 1.566 ± 0.028	1.756MetVal: 1.756 ± 0.034	0.215MetTrp: 0.215 ± 0.011	0.956MetTyr: 0.956 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.372AsnAla: 3.372 ± 0.049	0.743AsnCys: 0.743 ± 0.027	2.669AsnAsp: 2.669 ± 0.048	3.948AsnGlu: 3.948 ± 0.06	2.006AsnPhe: 2.006 ± 0.038	3.74AsnGly: 3.74 ± 0.058	1.017AsnHis: 1.017 ± 0.031	5.319AsnIle: 5.319 ± 0.074	4.184AsnLys: 4.184 ± 0.058	4.806AsnLeu: 4.806 ± 0.067	1.682AsnMet: 1.682 ± 0.034	3.234AsnAsn: 3.234 ± 0.063	1.95AsnPro: 1.95 ± 0.043	2.346AsnGln: 2.346 ± 0.048	1.987AsnArg: 1.987 ± 0.041	3.562AsnSer: 3.562 ± 0.055	3.153AsnThr: 3.153 ± 0.05	3.405AsnVal: 3.405 ± 0.049	0.507AsnTrp: 0.507 ± 0.021	2.609AsnTyr: 2.609 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	1.567ProAla: 1.567 ± 0.03	0.372ProCys: 0.372 ± 0.017	1.714ProAsp: 1.714 ± 0.034	2.101ProGlu: 2.101 ± 0.042	1.43ProPhe: 1.43 ± 0.034	1.564ProGly: 1.564 ± 0.039	0.453ProHis: 0.453 ± 0.019	2.614ProIle: 2.614 ± 0.04	1.875ProLys: 1.875 ± 0.04	2.434ProLeu: 2.434 ± 0.042	0.768ProMet: 0.768 ± 0.02	1.547ProAsn: 1.547 ± 0.035	0.564ProPro: 0.564 ± 0.018	0.873ProGln: 0.873 ± 0.025	0.763ProArg: 0.763 ± 0.024	1.712ProSer: 1.712 ± 0.038	1.543ProThr: 1.543 ± 0.038	2.086ProVal: 2.086 ± 0.039	0.282ProTrp: 0.282 ± 0.013	1.335ProTyr: 1.335 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	2.056GlnAla: 2.056 ± 0.036	0.419GlnCys: 0.419 ± 0.016	1.555GlnAsp: 1.555 ± 0.029	2.577GlnGlu: 2.577 ± 0.05	1.315GlnPhe: 1.315 ± 0.03	1.821GlnGly: 1.821 ± 0.043	0.412GlnHis: 0.412 ± 0.018	3.098GlnIle: 3.098 ± 0.048	2.639GlnLys: 2.639 ± 0.04	3.036GlnLeu: 3.036 ± 0.05	1.085GlnMet: 1.085 ± 0.026	1.985GlnAsn: 1.985 ± 0.039	0.749GlnPro: 0.749 ± 0.022	1.12GlnGln: 1.12 ± 0.027	1.135GlnArg: 1.135 ± 0.03	2.009GlnSer: 2.009 ± 0.04	1.8GlnThr: 1.8 ± 0.043	2.03GlnVal: 2.03 ± 0.042	0.278GlnTrp: 0.278 ± 0.016	1.645GlnTyr: 1.645 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	1.939ArgAla: 1.939 ± 0.041	0.462ArgCys: 0.462 ± 0.017	1.618ArgAsp: 1.618 ± 0.035	2.652ArgGlu: 2.652 ± 0.042	1.516ArgPhe: 1.516 ± 0.038	1.879ArgGly: 1.879 ± 0.033	0.497ArgHis: 0.497 ± 0.02	3.227ArgIle: 3.227 ± 0.05	2.901ArgLys: 2.901 ± 0.048	3.123ArgLeu: 3.123 ± 0.052	1.132ArgMet: 1.132 ± 0.033	2.018ArgAsn: 2.018 ± 0.04	0.894ArgPro: 0.894 ± 0.025	1.196ArgGln: 1.196 ± 0.033	1.321ArgArg: 1.321 ± 0.033	1.72ArgSer: 1.72 ± 0.036	1.631ArgThr: 1.631 ± 0.035	2.139ArgVal: 2.139 ± 0.045	0.291ArgTrp: 0.291 ± 0.017	1.531ArgTyr: 1.531 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.799SerAla: 3.799 ± 0.062	0.787SerCys: 0.787 ± 0.024	3.626SerAsp: 3.626 ± 0.053	4.195SerGlu: 4.195 ± 0.058	3.072SerPhe: 3.072 ± 0.051	4.598SerGly: 4.598 ± 0.066	0.961SerHis: 0.961 ± 0.029	5.91SerIle: 5.91 ± 0.075	4.861SerLys: 4.861 ± 0.063	5.729SerLeu: 5.729 ± 0.069	1.796SerMet: 1.796 ± 0.038	3.559SerAsn: 3.559 ± 0.052	1.557SerPro: 1.557 ± 0.029	2.03SerGln: 2.03 ± 0.04	1.993SerArg: 1.993 ± 0.039	4.399SerSer: 4.399 ± 0.084	3.566SerThr: 3.566 ± 0.067	4.208SerVal: 4.208 ± 0.058	0.584SerTrp: 0.584 ± 0.021	2.92SerTyr: 2.92 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.8ThrAla: 3.8 ± 0.068	0.642ThrCys: 0.642 ± 0.022	3.165ThrAsp: 3.165 ± 0.064	3.336ThrGlu: 3.336 ± 0.049	2.27ThrPhe: 2.27 ± 0.04	3.982ThrGly: 3.982 ± 0.06	0.791ThrHis: 0.791 ± 0.026	4.994ThrIle: 4.994 ± 0.064	3.958ThrLys: 3.958 ± 0.059	4.932ThrLeu: 4.932 ± 0.062	1.38ThrMet: 1.38 ± 0.033	3.034ThrAsn: 3.034 ± 0.048	1.749ThrPro: 1.749 ± 0.036	1.818ThrGln: 1.818 ± 0.04	1.595ThrArg: 1.595 ± 0.032	3.542ThrSer: 3.542 ± 0.055	3.219ThrThr: 3.219 ± 0.069	4.028ThrVal: 4.028 ± 0.066	0.449ThrTrp: 0.449 ± 0.018	2.33ThrTyr: 2.33 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	4.059ValAla: 4.059 ± 0.06	0.916ValCys: 0.916 ± 0.029	3.517ValAsp: 3.517 ± 0.055	4.173ValGlu: 4.173 ± 0.058	2.79ValPhe: 2.79 ± 0.041	3.915ValGly: 3.915 ± 0.06	0.872ValHis: 0.872 ± 0.026	6.02ValIle: 6.02 ± 0.073	4.729ValLys: 4.729 ± 0.061	6.101ValLeu: 6.101 ± 0.061	1.827ValMet: 1.827 ± 0.039	3.512ValAsn: 3.512 ± 0.05	1.87ValPro: 1.87 ± 0.037	1.657ValGln: 1.657 ± 0.033	2.046ValArg: 2.046 ± 0.039	4.567ValSer: 4.567 ± 0.049	3.884ValThr: 3.884 ± 0.062	4.238ValVal: 4.238 ± 0.066	0.521ValTrp: 0.521 ± 0.018	2.581ValTyr: 2.581 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.455TrpAla: 0.455 ± 0.02	0.131TrpCys: 0.131 ± 0.01	0.488TrpAsp: 0.488 ± 0.018	0.598TrpGlu: 0.598 ± 0.02	0.412TrpPhe: 0.412 ± 0.019	0.626TrpGly: 0.626 ± 0.022	0.137TrpHis: 0.137 ± 0.009	0.702TrpIle: 0.702 ± 0.021	0.657TrpLys: 0.657 ± 0.024	0.799TrpLeu: 0.799 ± 0.02	0.28TrpMet: 0.28 ± 0.014	0.613TrpAsn: 0.613 ± 0.021	0.191TrpPro: 0.191 ± 0.012	0.3TrpGln: 0.3 ± 0.014	0.287TrpArg: 0.287 ± 0.014	0.564TrpSer: 0.564 ± 0.022	0.4TrpThr: 0.4 ± 0.016	0.462TrpVal: 0.462 ± 0.021	0.108TrpTrp: 0.108 ± 0.01	0.39TrpTyr: 0.39 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.561TyrAla: 2.561 ± 0.046	0.664TyrCys: 0.664 ± 0.023	2.658TyrAsp: 2.658 ± 0.068	3.184TyrGlu: 3.184 ± 0.052	2.109TyrPhe: 2.109 ± 0.044	2.756TyrGly: 2.756 ± 0.046	0.915TyrHis: 0.915 ± 0.025	3.667TyrIle: 3.667 ± 0.056	3.106TyrLys: 3.106 ± 0.052	4.091TyrLeu: 4.091 ± 0.052	1.144TyrMet: 1.144 ± 0.029	2.538TyrAsn: 2.538 ± 0.044	1.348TyrPro: 1.348 ± 0.035	1.863TyrGln: 1.863 ± 0.039	1.616TyrArg: 1.616 ± 0.031	2.842TyrSer: 2.842 ± 0.049	2.319TyrThr: 2.319 ± 0.049	2.609TyrVal: 2.609 ± 0.041	0.422TyrTrp: 0.422 ± 0.019	2.319TyrTyr: 2.319 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4293 proteins (1421011 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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