Amino acid dipepetide frequency for Olive latent virus 2 (isolate Italy) (OLV-2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.157AlaAla: 8.157 ± 3.458
0.408AlaCys: 0.408 ± 0.294
4.894AlaAsp: 4.894 ± 1.295
4.486AlaGlu: 4.486 ± 1.214
4.078AlaPhe: 4.078 ± 1.402
7.341AlaGly: 7.341 ± 1.414
3.67AlaHis: 3.67 ± 1.447
1.223AlaIle: 1.223 ± 0.882
5.302AlaLys: 5.302 ± 2.083
6.117AlaLeu: 6.117 ± 0.842
2.855AlaMet: 2.855 ± 1.207
1.223AlaAsn: 1.223 ± 0.348
3.263AlaPro: 3.263 ± 2.352
2.855AlaGln: 2.855 ± 0.734
6.933AlaArg: 6.933 ± 2.681
3.67AlaSer: 3.67 ± 1.413
4.486AlaThr: 4.486 ± 0.654
7.341AlaVal: 7.341 ± 1.657
0.0AlaTrp: 0.0 ± 0.0
3.67AlaTyr: 3.67 ± 1.563
0.0AlaXaa: 0.0 ± 0.0
Cys
0.816CysAla: 0.816 ± 0.588
0.816CysCys: 0.816 ± 0.264
1.223CysAsp: 1.223 ± 0.505
0.816CysGlu: 0.816 ± 0.636
0.816CysPhe: 0.816 ± 0.264
1.631CysGly: 1.631 ± 0.528
0.408CysHis: 0.408 ± 0.294
0.0CysIle: 0.0 ± 0.0
1.631CysLys: 1.631 ± 1.176
1.223CysLeu: 1.223 ± 0.505
0.408CysMet: 0.408 ± 0.318
0.0CysAsn: 0.0 ± 0.0
1.631CysPro: 1.631 ± 0.528
0.408CysGln: 0.408 ± 0.294
0.0CysArg: 0.0 ± 0.0
1.631CysSer: 1.631 ± 0.802
0.816CysThr: 0.816 ± 0.264
0.408CysVal: 0.408 ± 0.294
0.0CysTrp: 0.0 ± 0.0
0.408CysTyr: 0.408 ± 0.318
0.0CysXaa: 0.0 ± 0.0
Asp
2.855AspAla: 2.855 ± 0.991
1.631AspCys: 1.631 ± 1.176
4.486AspAsp: 4.486 ± 1.743
2.855AspGlu: 2.855 ± 0.975
6.933AspPhe: 6.933 ± 2.938
3.67AspGly: 3.67 ± 0.707
0.0AspHis: 0.0 ± 0.0
1.223AspIle: 1.223 ± 0.619
3.263AspLys: 3.263 ± 0.948
4.078AspLeu: 4.078 ± 0.919
1.631AspMet: 1.631 ± 0.725
0.408AspAsn: 0.408 ± 0.318
3.67AspPro: 3.67 ± 0.719
2.447AspGln: 2.447 ± 0.793
4.486AspArg: 4.486 ± 0.639
4.078AspSer: 4.078 ± 1.267
0.0AspThr: 0.0 ± 0.0
4.078AspVal: 4.078 ± 1.022
2.039AspTrp: 2.039 ± 0.741
1.223AspTyr: 1.223 ± 0.954
0.0AspXaa: 0.0 ± 0.0
Glu
6.117GluAla: 6.117 ± 1.69
0.816GluCys: 0.816 ± 0.264
3.263GluAsp: 3.263 ± 0.761
1.631GluGlu: 1.631 ± 0.725
3.67GluPhe: 3.67 ± 1.608
8.157GluGly: 8.157 ± 1.825
2.855GluHis: 2.855 ± 0.792
3.263GluIle: 3.263 ± 1.142
2.855GluLys: 2.855 ± 0.654
6.525GluLeu: 6.525 ± 2.098
2.039GluMet: 2.039 ± 1.049
1.223GluAsn: 1.223 ± 0.348
2.855GluPro: 2.855 ± 1.737
1.223GluGln: 1.223 ± 0.912
3.67GluArg: 3.67 ± 0.888
5.302GluSer: 5.302 ± 0.905
1.631GluThr: 1.631 ± 0.787
4.894GluVal: 4.894 ± 1.223
0.816GluTrp: 0.816 ± 0.264
0.408GluTyr: 0.408 ± 0.318
0.0GluXaa: 0.0 ± 0.0
Phe
3.67PheAla: 3.67 ± 1.206
0.408PheCys: 0.408 ± 0.318
2.039PheAsp: 2.039 ± 0.69
6.117PheGlu: 6.117 ± 1.768
3.263PhePhe: 3.263 ± 1.841
3.263PheGly: 3.263 ± 0.681
0.816PheHis: 0.816 ± 0.636
1.223PheIle: 1.223 ± 0.505
2.855PheLys: 2.855 ± 0.991
5.71PheLeu: 5.71 ± 0.812
0.408PheMet: 0.408 ± 0.318
2.855PheAsn: 2.855 ± 0.764
3.67PhePro: 3.67 ± 0.746
1.631PheGln: 1.631 ± 0.854
2.039PheArg: 2.039 ± 0.831
5.302PheSer: 5.302 ± 2.226
2.039PheThr: 2.039 ± 0.69
4.078PheVal: 4.078 ± 1.332
0.408PheTrp: 0.408 ± 0.318
3.67PheTyr: 3.67 ± 1.237
0.0PheXaa: 0.0 ± 0.0
Gly
4.486GlyAla: 4.486 ± 1.683
0.816GlyCys: 0.816 ± 0.264
3.263GlyAsp: 3.263 ± 0.857
4.486GlyGlu: 4.486 ± 1.477
1.223GlyPhe: 1.223 ± 0.348
4.894GlyGly: 4.894 ± 1.767
0.816GlyHis: 0.816 ± 0.264
3.263GlyIle: 3.263 ± 1.093
4.078GlyLys: 4.078 ± 1.074
8.564GlyLeu: 8.564 ± 0.51
2.039GlyMet: 2.039 ± 0.977
2.447GlyAsn: 2.447 ± 0.793
1.631GlyPro: 1.631 ± 0.528
0.816GlyGln: 0.816 ± 0.502
4.486GlyArg: 4.486 ± 1.436
6.525GlySer: 6.525 ± 3.561
4.078GlyThr: 4.078 ± 2.152
4.078GlyVal: 4.078 ± 0.862
0.816GlyTrp: 0.816 ± 0.264
0.816GlyTyr: 0.816 ± 0.472
0.0GlyXaa: 0.0 ± 0.0
His
2.855HisAla: 2.855 ± 1.376
0.0HisCys: 0.0 ± 0.0
1.631HisAsp: 1.631 ± 0.528
2.039HisGlu: 2.039 ± 0.723
2.039HisPhe: 2.039 ± 1.11
1.223HisGly: 1.223 ± 0.619
0.816HisHis: 0.816 ± 0.588
1.631HisIle: 1.631 ± 0.814
0.816HisLys: 0.816 ± 0.569
1.631HisLeu: 1.631 ± 0.404
0.408HisMet: 0.408 ± 0.294
0.408HisAsn: 0.408 ± 0.294
1.223HisPro: 1.223 ± 0.46
0.816HisGln: 0.816 ± 0.588
1.631HisArg: 1.631 ± 0.528
2.039HisSer: 2.039 ± 0.82
1.223HisThr: 1.223 ± 0.882
3.263HisVal: 3.263 ± 1.257
1.223HisTrp: 1.223 ± 0.882
0.408HisTyr: 0.408 ± 0.318
0.0HisXaa: 0.0 ± 0.0
Ile
2.039IleAla: 2.039 ± 0.69
0.408IleCys: 0.408 ± 0.294
2.855IleAsp: 2.855 ± 0.764
2.447IleGlu: 2.447 ± 0.92
1.223IlePhe: 1.223 ± 0.46
0.408IleGly: 0.408 ± 0.294
1.223IleHis: 1.223 ± 0.685
0.408IleIle: 0.408 ± 0.294
2.855IleLys: 2.855 ± 1.178
2.447IleLeu: 2.447 ± 1.07
1.223IleMet: 1.223 ± 0.505
2.039IleAsn: 2.039 ± 1.515
2.855IlePro: 2.855 ± 0.459
0.408IleGln: 0.408 ± 0.486
2.855IleArg: 2.855 ± 0.459
3.67IleSer: 3.67 ± 1.193
0.816IleThr: 0.816 ± 0.264
2.447IleVal: 2.447 ± 0.839
0.816IleTrp: 0.816 ± 0.502
0.408IleTyr: 0.408 ± 0.318
0.0IleXaa: 0.0 ± 0.0
Lys
4.486LysAla: 4.486 ± 1.932
0.408LysCys: 0.408 ± 0.318
2.447LysAsp: 2.447 ± 0.768
2.447LysGlu: 2.447 ± 1.01
4.486LysPhe: 4.486 ± 0.922
2.447LysGly: 2.447 ± 1.01
0.408LysHis: 0.408 ± 0.318
1.223LysIle: 1.223 ± 0.46
6.525LysLys: 6.525 ± 2.901
4.078LysLeu: 4.078 ± 1.212
1.631LysMet: 1.631 ± 1.176
0.816LysAsn: 0.816 ± 0.264
2.039LysPro: 2.039 ± 0.69
0.408LysGln: 0.408 ± 0.528
2.447LysArg: 2.447 ± 0.617
6.525LysSer: 6.525 ± 1.092
3.263LysThr: 3.263 ± 1.875
3.263LysVal: 3.263 ± 1.603
0.816LysTrp: 0.816 ± 0.636
2.855LysTyr: 2.855 ± 0.734
0.0LysXaa: 0.0 ± 0.0
Leu
7.341LeuAla: 7.341 ± 1.201
1.223LeuCys: 1.223 ± 0.46
6.117LeuAsp: 6.117 ± 0.815
6.933LeuGlu: 6.933 ± 0.801
5.302LeuPhe: 5.302 ± 1.458
3.67LeuGly: 3.67 ± 0.754
2.039LeuHis: 2.039 ± 0.615
2.855LeuIle: 2.855 ± 1.302
7.341LeuLys: 7.341 ± 2.366
6.933LeuLeu: 6.933 ± 1.37
2.447LeuMet: 2.447 ± 0.575
3.67LeuAsn: 3.67 ± 0.888
4.486LeuPro: 4.486 ± 1.3
2.039LeuGln: 2.039 ± 0.382
3.263LeuArg: 3.263 ± 1.093
7.341LeuSer: 7.341 ± 1.311
4.078LeuThr: 4.078 ± 0.764
6.525LeuVal: 6.525 ± 1.285
1.631LeuTrp: 1.631 ± 0.814
2.855LeuTyr: 2.855 ± 0.654
0.0LeuXaa: 0.0 ± 0.0
Met
3.263MetAla: 3.263 ± 1.626
0.408MetCys: 0.408 ± 0.318
1.631MetAsp: 1.631 ± 0.528
1.223MetGlu: 1.223 ± 0.46
1.223MetPhe: 1.223 ± 0.685
2.039MetGly: 2.039 ± 0.977
0.408MetHis: 0.408 ± 0.294
0.408MetIle: 0.408 ± 0.318
0.0MetLys: 0.0 ± 0.0
2.855MetLeu: 2.855 ± 0.938
0.408MetMet: 0.408 ± 0.318
1.631MetAsn: 1.631 ± 0.725
0.408MetPro: 0.408 ± 0.318
1.223MetGln: 1.223 ± 0.46
1.631MetArg: 1.631 ± 0.404
4.078MetSer: 4.078 ± 1.029
0.408MetThr: 0.408 ± 0.294
2.039MetVal: 2.039 ± 0.712
0.0MetTrp: 0.0 ± 0.0
0.816MetTyr: 0.816 ± 0.588
0.0MetXaa: 0.0 ± 0.0
Asn
1.223AsnAla: 1.223 ± 0.785
0.408AsnCys: 0.408 ± 0.318
0.408AsnAsp: 0.408 ± 0.318
1.223AsnGlu: 1.223 ± 0.882
0.408AsnPhe: 0.408 ± 0.318
1.631AsnGly: 1.631 ± 0.82
1.631AsnHis: 1.631 ± 1.003
0.816AsnIle: 0.816 ± 0.588
0.816AsnLys: 0.816 ± 0.264
2.855AsnLeu: 2.855 ± 0.654
1.223AsnMet: 1.223 ± 0.505
0.0AsnAsn: 0.0 ± 0.0
1.223AsnPro: 1.223 ± 0.348
2.039AsnGln: 2.039 ± 0.977
1.631AsnArg: 1.631 ± 0.803
1.631AsnSer: 1.631 ± 0.945
2.855AsnThr: 2.855 ± 0.764
2.447AsnVal: 2.447 ± 0.617
0.816AsnTrp: 0.816 ± 0.588
1.223AsnTyr: 1.223 ± 0.348
0.0AsnXaa: 0.0 ± 0.0
Pro
4.078ProAla: 4.078 ± 0.862
0.816ProCys: 0.816 ± 0.588
2.447ProAsp: 2.447 ± 0.793
1.223ProGlu: 1.223 ± 0.954
1.631ProPhe: 1.631 ± 0.528
4.486ProGly: 4.486 ± 1.081
2.039ProHis: 2.039 ± 0.615
3.263ProIle: 3.263 ± 1.144
1.223ProLys: 1.223 ± 0.709
5.71ProLeu: 5.71 ± 0.994
2.039ProMet: 2.039 ± 0.892
1.631ProAsn: 1.631 ± 0.659
2.039ProPro: 2.039 ± 0.812
2.855ProGln: 2.855 ± 1.618
4.078ProArg: 4.078 ± 1.326
2.855ProSer: 2.855 ± 0.915
2.447ProThr: 2.447 ± 1.505
4.078ProVal: 4.078 ± 1.09
0.408ProTrp: 0.408 ± 0.528
1.631ProTyr: 1.631 ± 0.659
0.0ProXaa: 0.0 ± 0.0
Gln
4.078GlnAla: 4.078 ± 1.222
0.816GlnCys: 0.816 ± 0.264
0.816GlnAsp: 0.816 ± 0.264
2.447GlnGlu: 2.447 ± 0.575
1.223GlnPhe: 1.223 ± 0.954
2.855GlnGly: 2.855 ± 1.689
0.816GlnHis: 0.816 ± 0.472
3.263GlnIle: 3.263 ± 1.199
0.408GlnLys: 0.408 ± 0.294
0.816GlnLeu: 0.816 ± 0.472
0.816GlnMet: 0.816 ± 0.264
1.223GlnAsn: 1.223 ± 0.46
2.039GlnPro: 2.039 ± 1.171
0.408GlnGln: 0.408 ± 0.294
1.631GlnArg: 1.631 ± 0.846
2.447GlnSer: 2.447 ± 0.948
2.855GlnThr: 2.855 ± 1.351
4.078GlnVal: 4.078 ± 0.519
1.223GlnTrp: 1.223 ± 0.46
0.816GlnTyr: 0.816 ± 0.569
0.0GlnXaa: 0.0 ± 0.0
Arg
6.525ArgAla: 6.525 ± 1.345
0.816ArgCys: 0.816 ± 0.264
4.078ArgAsp: 4.078 ± 1.201
4.894ArgGlu: 4.894 ± 1.017
3.67ArgPhe: 3.67 ± 0.857
2.447ArgGly: 2.447 ± 1.557
0.816ArgHis: 0.816 ± 0.552
1.223ArgIle: 1.223 ± 0.505
2.447ArgLys: 2.447 ± 1.907
5.71ArgLeu: 5.71 ± 0.774
2.447ArgMet: 2.447 ± 1.07
1.223ArgAsn: 1.223 ± 0.348
3.67ArgPro: 3.67 ± 1.134
2.039ArgGln: 2.039 ± 1.111
9.38ArgArg: 9.38 ± 4.323
4.078ArgSer: 4.078 ± 2.008
4.894ArgThr: 4.894 ± 1.149
6.117ArgVal: 6.117 ± 1.471
0.816ArgTrp: 0.816 ± 0.472
0.408ArgTyr: 0.408 ± 0.318
0.0ArgXaa: 0.0 ± 0.0
Ser
7.749SerAla: 7.749 ± 1.056
2.447SerCys: 2.447 ± 1.01
2.855SerAsp: 2.855 ± 1.138
3.67SerGlu: 3.67 ± 1.027
4.894SerPhe: 4.894 ± 0.294
5.302SerGly: 5.302 ± 2.12
1.223SerHis: 1.223 ± 0.709
2.039SerIle: 2.039 ± 0.67
3.67SerLys: 3.67 ± 0.962
8.564SerLeu: 8.564 ± 1.212
0.816SerMet: 0.816 ± 0.264
1.631SerAsn: 1.631 ± 0.814
2.855SerPro: 2.855 ± 1.376
3.67SerGln: 3.67 ± 1.54
5.71SerArg: 5.71 ± 1.274
5.71SerSer: 5.71 ± 1.022
4.078SerThr: 4.078 ± 1.222
8.564SerVal: 8.564 ± 3.105
1.631SerTrp: 1.631 ± 0.558
4.894SerTyr: 4.894 ± 1.318
0.0SerXaa: 0.0 ± 0.0
Thr
4.078ThrAla: 4.078 ± 1.069
0.408ThrCys: 0.408 ± 0.294
1.223ThrAsp: 1.223 ± 0.505
2.447ThrGlu: 2.447 ± 1.528
3.263ThrPhe: 3.263 ± 0.716
4.486ThrGly: 4.486 ± 0.539
1.223ThrHis: 1.223 ± 0.882
1.223ThrIle: 1.223 ± 0.505
1.223ThrLys: 1.223 ± 0.505
4.486ThrLeu: 4.486 ± 0.392
0.816ThrMet: 0.816 ± 0.291
1.631ThrAsn: 1.631 ± 0.47
1.631ThrPro: 1.631 ± 0.528
2.447ThrGln: 2.447 ± 1.014
2.039ThrArg: 2.039 ± 1.106
4.894ThrSer: 4.894 ± 2.675
0.816ThrThr: 0.816 ± 0.472
4.486ThrVal: 4.486 ± 1.269
0.816ThrTrp: 0.816 ± 0.588
3.67ThrTyr: 3.67 ± 0.335
0.0ThrXaa: 0.0 ± 0.0
Val
5.71ValAla: 5.71 ± 2.089
1.223ValCys: 1.223 ± 0.505
6.117ValAsp: 6.117 ± 0.942
7.341ValGlu: 7.341 ± 0.872
2.447ValPhe: 2.447 ± 0.696
2.855ValGly: 2.855 ± 0.95
2.855ValHis: 2.855 ± 0.717
2.855ValIle: 2.855 ± 0.963
4.486ValLys: 4.486 ± 0.392
4.486ValLeu: 4.486 ± 1.815
1.223ValMet: 1.223 ± 0.954
1.631ValAsn: 1.631 ± 0.945
7.749ValPro: 7.749 ± 2.167
4.078ValGln: 4.078 ± 1.486
5.302ValArg: 5.302 ± 1.024
6.933ValSer: 6.933 ± 1.153
5.71ValThr: 5.71 ± 1.381
3.67ValVal: 3.67 ± 1.748
1.223ValTrp: 1.223 ± 0.505
1.631ValTyr: 1.631 ± 0.854
0.0ValXaa: 0.0 ± 0.0
Trp
0.408TrpAla: 0.408 ± 0.294
0.408TrpCys: 0.408 ± 0.318
0.816TrpAsp: 0.816 ± 0.636
1.631TrpGlu: 1.631 ± 0.528
1.631TrpPhe: 1.631 ± 0.528
0.0TrpGly: 0.0 ± 0.0
0.816TrpHis: 0.816 ± 0.588
1.631TrpIle: 1.631 ± 0.82
0.816TrpLys: 0.816 ± 0.588
0.816TrpLeu: 0.816 ± 0.264
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.816TrpPro: 0.816 ± 0.264
1.631TrpGln: 1.631 ± 0.558
2.039TrpArg: 2.039 ± 0.812
1.631TrpSer: 1.631 ± 0.787
0.0TrpThr: 0.0 ± 0.0
0.816TrpVal: 0.816 ± 0.636
0.408TrpTrp: 0.408 ± 0.318
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.039TyrAla: 2.039 ± 0.652
0.408TyrCys: 0.408 ± 0.318
2.447TyrAsp: 2.447 ± 0.493
2.855TyrGlu: 2.855 ± 0.938
2.039TyrPhe: 2.039 ± 0.914
0.816TyrGly: 0.816 ± 0.792
2.447TyrHis: 2.447 ± 0.617
0.816TyrIle: 0.816 ± 0.472
0.408TyrLys: 0.408 ± 0.294
4.486TyrLeu: 4.486 ± 1.341
0.816TyrMet: 0.816 ± 0.264
0.816TyrAsn: 0.816 ± 0.792
1.223TyrPro: 1.223 ± 0.745
1.631TyrGln: 1.631 ± 0.528
2.447TyrArg: 2.447 ± 0.493
1.631TyrSer: 1.631 ± 0.995
1.223TyrThr: 1.223 ± 0.46
2.855TyrVal: 2.855 ± 0.459
0.408TyrTrp: 0.408 ± 0.318
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2453 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski