Amino acid dipepetide frequency for Bacteroides fluxus YIT 12057

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.158AlaAla: 6.158 ± 0.085	1.106AlaCys: 1.106 ± 0.027	4.345AlaAsp: 4.345 ± 0.059	4.831AlaGlu: 4.831 ± 0.071	3.283AlaPhe: 3.283 ± 0.05	5.574AlaGly: 5.574 ± 0.078	1.246AlaHis: 1.246 ± 0.033	4.55AlaIle: 4.55 ± 0.069	4.032AlaLys: 4.032 ± 0.063	6.832AlaLeu: 6.832 ± 0.091	2.001AlaMet: 2.001 ± 0.039	3.057AlaAsn: 3.057 ± 0.055	2.407AlaPro: 2.407 ± 0.043	2.646AlaGln: 2.646 ± 0.042	3.393AlaArg: 3.393 ± 0.057	4.352AlaSer: 4.352 ± 0.068	3.891AlaThr: 3.891 ± 0.055	5.154AlaVal: 5.154 ± 0.07	0.787AlaTrp: 0.787 ± 0.028	3.028AlaTyr: 3.028 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.798CysAla: 0.798 ± 0.026	0.22CysCys: 0.22 ± 0.014	0.636CysAsp: 0.636 ± 0.025	0.674CysGlu: 0.674 ± 0.023	0.677CysPhe: 0.677 ± 0.023	1.066CysGly: 1.066 ± 0.03	0.306CysHis: 0.306 ± 0.016	0.959CysIle: 0.959 ± 0.034	0.714CysLys: 0.714 ± 0.027	1.232CysLeu: 1.232 ± 0.034	0.368CysMet: 0.368 ± 0.017	0.59CysAsn: 0.59 ± 0.022	0.568CysPro: 0.568 ± 0.021	0.376CysGln: 0.376 ± 0.016	0.751CysArg: 0.751 ± 0.028	0.851CysSer: 0.851 ± 0.029	0.72CysThr: 0.72 ± 0.025	0.76CysVal: 0.76 ± 0.026	0.167CysTrp: 0.167 ± 0.012	0.581CysTyr: 0.581 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	4.108AspAla: 4.108 ± 0.059	0.658AspCys: 0.658 ± 0.025	2.574AspAsp: 2.574 ± 0.052	3.737AspGlu: 3.737 ± 0.064	3.026AspPhe: 3.026 ± 0.044	4.127AspGly: 4.127 ± 0.069	0.788AspHis: 0.788 ± 0.023	4.032AspIle: 4.032 ± 0.054	3.907AspLys: 3.907 ± 0.061	4.497AspLeu: 4.497 ± 0.053	1.639AspMet: 1.639 ± 0.037	2.687AspAsn: 2.687 ± 0.055	1.721AspPro: 1.721 ± 0.037	1.085AspGln: 1.085 ± 0.031	2.488AspArg: 2.488 ± 0.047	3.055AspSer: 3.055 ± 0.059	2.748AspThr: 2.748 ± 0.048	3.49AspVal: 3.49 ± 0.044	0.872AspTrp: 0.872 ± 0.03	2.926AspTyr: 2.926 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	4.999GluAla: 4.999 ± 0.073	0.664GluCys: 0.664 ± 0.024	3.275GluAsp: 3.275 ± 0.057	5.3GluGlu: 5.3 ± 0.075	2.45GluPhe: 2.45 ± 0.048	4.324GluGly: 4.324 ± 0.06	1.268GluHis: 1.268 ± 0.032	4.492GluIle: 4.492 ± 0.063	5.226GluLys: 5.226 ± 0.062	6.193GluLeu: 6.193 ± 0.071	2.091GluMet: 2.091 ± 0.035	3.527GluAsn: 3.527 ± 0.061	1.791GluPro: 1.791 ± 0.045	2.655GluGln: 2.655 ± 0.049	3.474GluArg: 3.474 ± 0.055	3.043GluSer: 3.043 ± 0.048	3.297GluThr: 3.297 ± 0.049	4.338GluVal: 4.338 ± 0.052	0.826GluTrp: 0.826 ± 0.027	2.77GluTyr: 2.77 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.057PheAla: 3.057 ± 0.051	0.72PheCys: 0.72 ± 0.024	2.621PheAsp: 2.621 ± 0.045	2.413PheGlu: 2.413 ± 0.043	2.363PhePhe: 2.363 ± 0.058	3.209PheGly: 3.209 ± 0.051	0.947PheHis: 0.947 ± 0.025	3.26PheIle: 3.26 ± 0.056	2.425PheLys: 2.425 ± 0.04	4.23PheLeu: 4.23 ± 0.074	1.287PheMet: 1.287 ± 0.032	2.302PheAsn: 2.302 ± 0.045	1.744PhePro: 1.744 ± 0.036	1.272PheGln: 1.272 ± 0.035	2.324PheArg: 2.324 ± 0.044	3.471PheSer: 3.471 ± 0.059	2.744PheThr: 2.744 ± 0.046	2.879PheVal: 2.879 ± 0.055	0.555PheTrp: 0.555 ± 0.021	2.021PheTyr: 2.021 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	4.473GlyAla: 4.473 ± 0.073	0.957GlyCys: 0.957 ± 0.031	3.477GlyAsp: 3.477 ± 0.056	4.391GlyGlu: 4.391 ± 0.057	3.172GlyPhe: 3.172 ± 0.05	4.975GlyGly: 4.975 ± 0.074	1.309GlyHis: 1.309 ± 0.037	5.415GlyIle: 5.415 ± 0.076	5.555GlyLys: 5.555 ± 0.064	5.875GlyLeu: 5.875 ± 0.088	2.332GlyMet: 2.332 ± 0.045	3.626GlyAsn: 3.626 ± 0.066	1.255GlyPro: 1.255 ± 0.037	2.148GlyGln: 2.148 ± 0.037	3.054GlyArg: 3.054 ± 0.051	4.015GlySer: 4.015 ± 0.069	4.28GlyThr: 4.28 ± 0.056	4.738GlyVal: 4.738 ± 0.064	1.038GlyTrp: 1.038 ± 0.033	3.47GlyTyr: 3.47 ± 0.066	0.0GlyXaa: 0.0 ± 0.0
His	1.28HisAla: 1.28 ± 0.032	0.34HisCys: 0.34 ± 0.016	0.935HisAsp: 0.935 ± 0.026	1.043HisGlu: 1.043 ± 0.027	1.035HisPhe: 1.035 ± 0.03	1.24HisGly: 1.24 ± 0.032	0.456HisHis: 0.456 ± 0.023	1.48HisIle: 1.48 ± 0.035	1.044HisLys: 1.044 ± 0.031	1.84HisLeu: 1.84 ± 0.039	0.359HisMet: 0.359 ± 0.016	0.912HisAsn: 0.912 ± 0.027	1.07HisPro: 1.07 ± 0.028	0.592HisGln: 0.592 ± 0.022	0.975HisArg: 0.975 ± 0.027	1.121HisSer: 1.121 ± 0.029	1.103HisThr: 1.103 ± 0.027	1.086HisVal: 1.086 ± 0.031	0.262HisTrp: 0.262 ± 0.014	0.954HisTyr: 0.954 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.151IleAla: 5.151 ± 0.067	0.978IleCys: 0.978 ± 0.03	4.014IleAsp: 4.014 ± 0.064	4.208IleGlu: 4.208 ± 0.067	2.78IlePhe: 2.78 ± 0.046	4.721IleGly: 4.721 ± 0.075	1.363IleHis: 1.363 ± 0.029	4.392IleIle: 4.392 ± 0.075	3.888IleLys: 3.888 ± 0.064	5.932IleLeu: 5.932 ± 0.087	1.475IleMet: 1.475 ± 0.033	3.346IleAsn: 3.346 ± 0.056	3.095IlePro: 3.095 ± 0.042	2.071IleGln: 2.071 ± 0.042	3.508IleArg: 3.508 ± 0.061	4.451IleSer: 4.451 ± 0.067	3.845IleThr: 3.845 ± 0.051	4.319IleVal: 4.319 ± 0.067	0.708IleTrp: 0.708 ± 0.024	2.819IleTyr: 2.819 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.883LysAla: 4.883 ± 0.063	0.574LysCys: 0.574 ± 0.023	3.926LysAsp: 3.926 ± 0.054	5.834LysGlu: 5.834 ± 0.07	2.07LysPhe: 2.07 ± 0.038	4.538LysGly: 4.538 ± 0.061	1.231LysHis: 1.231 ± 0.032	3.996LysIle: 3.996 ± 0.06	5.023LysLys: 5.023 ± 0.075	5.249LysLeu: 5.249 ± 0.069	2.042LysMet: 2.042 ± 0.04	3.448LysAsn: 3.448 ± 0.055	2.18LysPro: 2.18 ± 0.046	2.55LysGln: 2.55 ± 0.049	3.224LysArg: 3.224 ± 0.05	3.303LysSer: 3.303 ± 0.052	3.441LysThr: 3.441 ± 0.054	4.252LysVal: 4.252 ± 0.059	0.746LysTrp: 0.746 ± 0.023	2.99LysTyr: 2.99 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	6.595LeuAla: 6.595 ± 0.089	1.425LeuCys: 1.425 ± 0.043	4.616LeuAsp: 4.616 ± 0.063	5.25LeuGlu: 5.25 ± 0.065	4.606LeuPhe: 4.606 ± 0.078	5.613LeuGly: 5.613 ± 0.074	1.872LeuHis: 1.872 ± 0.037	5.275LeuIle: 5.275 ± 0.075	6.321LeuLys: 6.321 ± 0.066	9.385LeuLeu: 9.385 ± 0.114	2.578LeuMet: 2.578 ± 0.05	4.556LeuAsn: 4.556 ± 0.058	4.259LeuPro: 4.259 ± 0.07	3.513LeuGln: 3.513 ± 0.053	4.38LeuArg: 4.38 ± 0.063	6.573LeuSer: 6.573 ± 0.072	5.104LeuThr: 5.104 ± 0.064	5.302LeuVal: 5.302 ± 0.071	1.159LeuTrp: 1.159 ± 0.033	3.736LeuTyr: 3.736 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	2.136MetAla: 2.136 ± 0.04	0.281MetCys: 0.281 ± 0.014	1.573MetAsp: 1.573 ± 0.038	1.957MetGlu: 1.957 ± 0.038	1.019MetPhe: 1.019 ± 0.029	1.888MetGly: 1.888 ± 0.041	0.468MetHis: 0.468 ± 0.019	1.614MetIle: 1.614 ± 0.04	2.547MetLys: 2.547 ± 0.039	2.596MetLeu: 2.596 ± 0.05	0.832MetMet: 0.832 ± 0.03	1.685MetAsn: 1.685 ± 0.036	1.223MetPro: 1.223 ± 0.031	1.157MetGln: 1.157 ± 0.03	1.344MetArg: 1.344 ± 0.031	1.531MetSer: 1.531 ± 0.035	1.534MetThr: 1.534 ± 0.038	1.626MetVal: 1.626 ± 0.039	0.259MetTrp: 0.259 ± 0.015	0.867MetTyr: 0.867 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	3.425AsnAla: 3.425 ± 0.061	0.547AsnCys: 0.547 ± 0.02	2.471AsnAsp: 2.471 ± 0.048	3.01AsnGlu: 3.01 ± 0.048	2.221AsnPhe: 2.221 ± 0.048	3.986AsnGly: 3.986 ± 0.063	0.938AsnHis: 0.938 ± 0.031	3.676AsnIle: 3.676 ± 0.058	2.994AsnLys: 2.994 ± 0.057	4.379AsnLeu: 4.379 ± 0.062	1.385AsnMet: 1.385 ± 0.032	2.576AsnAsn: 2.576 ± 0.052	2.441AsnPro: 2.441 ± 0.047	1.492AsnGln: 1.492 ± 0.035	2.613AsnArg: 2.613 ± 0.043	2.733AsnSer: 2.733 ± 0.05	2.578AsnThr: 2.578 ± 0.053	3.213AsnVal: 3.213 ± 0.06	0.674AsnTrp: 0.674 ± 0.025	2.289AsnTyr: 2.289 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	3.053ProAla: 3.053 ± 0.053	0.423ProCys: 0.423 ± 0.022	2.606ProAsp: 2.606 ± 0.044	3.428ProGlu: 3.428 ± 0.052	1.892ProPhe: 1.892 ± 0.037	2.648ProGly: 2.648 ± 0.045	0.744ProHis: 0.744 ± 0.022	2.157ProIle: 2.157 ± 0.039	1.942ProLys: 1.942 ± 0.037	3.377ProLeu: 3.377 ± 0.052	0.946ProMet: 0.946 ± 0.027	1.577ProAsn: 1.577 ± 0.038	0.833ProPro: 0.833 ± 0.028	1.398ProGln: 1.398 ± 0.039	1.357ProArg: 1.357 ± 0.037	2.144ProSer: 2.144 ± 0.037	1.838ProThr: 1.838 ± 0.038	3.14ProVal: 3.14 ± 0.045	0.44ProTrp: 0.44 ± 0.019	1.778ProTyr: 1.778 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.612GlnAla: 2.612 ± 0.048	0.311GlnCys: 0.311 ± 0.015	1.599GlnAsp: 1.599 ± 0.036	2.424GlnGlu: 2.424 ± 0.042	1.251GlnPhe: 1.251 ± 0.035	2.082GlnGly: 2.082 ± 0.041	0.655GlnHis: 0.655 ± 0.026	2.213GlnIle: 2.213 ± 0.041	2.44GlnLys: 2.44 ± 0.048	3.206GlnLeu: 3.206 ± 0.056	1.012GlnMet: 1.012 ± 0.026	1.694GlnAsn: 1.694 ± 0.035	1.336GlnPro: 1.336 ± 0.033	1.539GlnGln: 1.539 ± 0.04	1.768GlnArg: 1.768 ± 0.037	1.928GlnSer: 1.928 ± 0.039	2.003GlnThr: 2.003 ± 0.045	2.108GlnVal: 2.108 ± 0.045	0.449GlnTrp: 0.449 ± 0.021	1.44GlnTyr: 1.44 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	2.926ArgAla: 2.926 ± 0.048	0.521ArgCys: 0.521 ± 0.02	2.221ArgAsp: 2.221 ± 0.041	3.279ArgGlu: 3.279 ± 0.054	2.345ArgPhe: 2.345 ± 0.041	2.553ArgGly: 2.553 ± 0.05	1.071ArgHis: 1.071 ± 0.033	3.867ArgIle: 3.867 ± 0.062	3.612ArgLys: 3.612 ± 0.059	4.707ArgLeu: 4.707 ± 0.069	1.702ArgMet: 1.702 ± 0.036	2.534ArgAsn: 2.534 ± 0.041	1.752ArgPro: 1.752 ± 0.039	2.002ArgGln: 2.002 ± 0.045	2.557ArgArg: 2.557 ± 0.055	2.496ArgSer: 2.496 ± 0.045	2.573ArgThr: 2.573 ± 0.044	2.743ArgVal: 2.743 ± 0.053	0.681ArgTrp: 0.681 ± 0.024	2.303ArgTyr: 2.303 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	4.256SerAla: 4.256 ± 0.058	0.872SerCys: 0.872 ± 0.027	3.206SerAsp: 3.206 ± 0.052	3.416SerGlu: 3.416 ± 0.054	3.286SerPhe: 3.286 ± 0.061	4.497SerGly: 4.497 ± 0.063	1.119SerHis: 1.119 ± 0.034	4.222SerIle: 4.222 ± 0.06	3.281SerLys: 3.281 ± 0.045	6.008SerLeu: 6.008 ± 0.067	1.529SerMet: 1.529 ± 0.033	2.635SerAsn: 2.635 ± 0.048	2.329SerPro: 2.329 ± 0.042	1.784SerGln: 1.784 ± 0.041	2.804SerArg: 2.804 ± 0.043	3.782SerSer: 3.782 ± 0.067	3.071SerThr: 3.071 ± 0.056	4.358SerVal: 4.358 ± 0.074	0.808SerTrp: 0.808 ± 0.024	2.692SerTyr: 2.692 ± 0.056	0.0SerXaa: 0.0 ± 0.0
Thr	4.223ThrAla: 4.223 ± 0.057	0.61ThrCys: 0.61 ± 0.025	3.424ThrAsp: 3.424 ± 0.049	3.362ThrGlu: 3.362 ± 0.058	2.673ThrPhe: 2.673 ± 0.052	4.488ThrGly: 4.488 ± 0.059	1.021ThrHis: 1.021 ± 0.025	3.473ThrIle: 3.473 ± 0.053	2.656ThrLys: 2.656 ± 0.049	5.475ThrLeu: 5.475 ± 0.067	1.18ThrMet: 1.18 ± 0.033	2.288ThrAsn: 2.288 ± 0.044	2.768ThrPro: 2.768 ± 0.045	1.705ThrGln: 1.705 ± 0.037	2.251ThrArg: 2.251 ± 0.043	3.202ThrSer: 3.202 ± 0.056	2.893ThrThr: 2.893 ± 0.056	4.126ThrVal: 4.126 ± 0.056	0.639ThrTrp: 0.639 ± 0.024	2.33ThrTyr: 2.33 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	4.755ValAla: 4.755 ± 0.075	1.013ValCys: 1.013 ± 0.028	3.481ValAsp: 3.481 ± 0.051	4.127ValGlu: 4.127 ± 0.065	2.961ValPhe: 2.961 ± 0.051	4.05ValGly: 4.05 ± 0.071	1.14ValHis: 1.14 ± 0.027	4.348ValIle: 4.348 ± 0.06	4.269ValLys: 4.269 ± 0.061	5.9ValLeu: 5.9 ± 0.073	1.788ValMet: 1.788 ± 0.039	3.355ValAsn: 3.355 ± 0.057	2.706ValPro: 2.706 ± 0.052	2.003ValGln: 2.003 ± 0.041	3.16ValArg: 3.16 ± 0.05	4.482ValSer: 4.482 ± 0.065	3.825ValThr: 3.825 ± 0.058	4.43ValVal: 4.43 ± 0.073	0.773ValTrp: 0.773 ± 0.03	2.667ValTyr: 2.667 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.803TrpAla: 0.803 ± 0.029	0.176TrpCys: 0.176 ± 0.011	0.686TrpAsp: 0.686 ± 0.026	0.823TrpGlu: 0.823 ± 0.027	0.569TrpPhe: 0.569 ± 0.022	0.922TrpGly: 0.922 ± 0.027	0.269TrpHis: 0.269 ± 0.015	0.807TrpIle: 0.807 ± 0.028	0.966TrpLys: 0.966 ± 0.033	1.152TrpLeu: 1.152 ± 0.032	0.454TrpMet: 0.454 ± 0.018	0.793TrpAsn: 0.793 ± 0.026	0.283TrpPro: 0.283 ± 0.014	0.547TrpGln: 0.547 ± 0.021	0.58TrpArg: 0.58 ± 0.021	0.652TrpSer: 0.652 ± 0.025	0.689TrpThr: 0.689 ± 0.026	0.71TrpVal: 0.71 ± 0.023	0.211TrpTrp: 0.211 ± 0.013	0.541TrpTyr: 0.541 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.984TyrAla: 2.984 ± 0.056	0.621TyrCys: 0.621 ± 0.023	2.478TyrAsp: 2.478 ± 0.043	2.497TyrGlu: 2.497 ± 0.044	2.166TyrPhe: 2.166 ± 0.043	3.055TyrGly: 3.055 ± 0.057	0.914TyrHis: 0.914 ± 0.029	2.835TyrIle: 2.835 ± 0.05	2.658TyrLys: 2.658 ± 0.046	4.053TyrLeu: 4.053 ± 0.061	1.139TyrMet: 1.139 ± 0.031	2.453TyrAsn: 2.453 ± 0.051	1.959TyrPro: 1.959 ± 0.041	1.535TyrGln: 1.535 ± 0.038	2.438TyrArg: 2.438 ± 0.047	2.768TyrSer: 2.768 ± 0.05	2.606TyrThr: 2.606 ± 0.051	2.461TyrVal: 2.461 ± 0.045	0.58TyrTrp: 0.58 ± 0.021	2.122TyrTyr: 2.122 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3920 proteins (1321397 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---