Amino acid dipepetide frequency for Circovirus-like genome DHCV-6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.854AlaAla: 4.854 ± 1.586
0.0AlaCys: 0.0 ± 0.0
3.236AlaAsp: 3.236 ± 2.217
1.618AlaGlu: 1.618 ± 1.109
6.472AlaPhe: 6.472 ± 3.291
3.236AlaGly: 3.236 ± 2.217
3.236AlaHis: 3.236 ± 0.953
4.854AlaIle: 4.854 ± 3.581
3.236AlaLys: 3.236 ± 0.953
3.236AlaLeu: 3.236 ± 1.915
1.618AlaMet: 1.618 ± 1.109
1.618AlaAsn: 1.618 ± 1.327
3.236AlaPro: 3.236 ± 1.749
1.618AlaGln: 1.618 ± 1.327
8.091AlaArg: 8.091 ± 2.531
6.472AlaSer: 6.472 ± 0.915
4.854AlaThr: 4.854 ± 2.027
3.236AlaVal: 3.236 ± 2.654
0.0AlaTrp: 0.0 ± 0.0
4.854AlaTyr: 4.854 ± 1.586
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
3.236CysPhe: 3.236 ± 2.217
0.0CysGly: 0.0 ± 0.0
1.618CysHis: 1.618 ± 1.109
0.0CysIle: 0.0 ± 0.0
1.618CysLys: 1.618 ± 1.109
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.618CysSer: 1.618 ± 1.109
0.0CysThr: 0.0 ± 0.0
1.618CysVal: 1.618 ± 1.109
0.0CysTrp: 0.0 ± 0.0
3.236CysTyr: 3.236 ± 2.217
0.0CysXaa: 0.0 ± 0.0
Asp
4.854AspAla: 4.854 ± 2.225
1.618AspCys: 1.618 ± 1.109
3.236AspAsp: 3.236 ± 2.217
3.236AspGlu: 3.236 ± 0.953
4.854AspPhe: 4.854 ± 2.225
3.236AspGly: 3.236 ± 1.749
1.618AspHis: 1.618 ± 1.109
4.854AspIle: 4.854 ± 1.012
1.618AspLys: 1.618 ± 1.109
6.472AspLeu: 6.472 ± 0.915
0.0AspMet: 0.0 ± 0.0
3.236AspAsn: 3.236 ± 2.217
3.236AspPro: 3.236 ± 0.953
0.0AspGln: 0.0 ± 0.0
1.618AspArg: 1.618 ± 1.109
3.236AspSer: 3.236 ± 2.654
0.0AspThr: 0.0 ± 0.0
6.472AspVal: 6.472 ± 3.05
0.0AspTrp: 0.0 ± 0.0
1.618AspTyr: 1.618 ± 1.327
0.0AspXaa: 0.0 ± 0.0
Glu
0.0GluAla: 0.0 ± 0.0
0.0GluCys: 0.0 ± 0.0
1.618GluAsp: 1.618 ± 1.109
0.0GluGlu: 0.0 ± 0.0
0.0GluPhe: 0.0 ± 0.0
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
4.854GluIle: 4.854 ± 2.225
4.854GluLys: 4.854 ± 3.326
4.854GluLeu: 4.854 ± 2.027
1.618GluMet: 1.618 ± 1.327
0.0GluAsn: 0.0 ± 0.0
3.236GluPro: 3.236 ± 2.217
1.618GluGln: 1.618 ± 1.109
1.618GluArg: 1.618 ± 1.109
0.0GluSer: 0.0 ± 0.0
3.236GluThr: 3.236 ± 0.953
1.618GluVal: 1.618 ± 1.109
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.854PheAsp: 4.854 ± 1.586
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
1.618PheHis: 1.618 ± 1.109
1.618PheIle: 1.618 ± 1.903
4.854PheLys: 4.854 ± 2.027
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.618PhePro: 1.618 ± 1.327
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
1.618PheSer: 1.618 ± 1.327
6.472PheThr: 6.472 ± 1.907
3.236PheVal: 3.236 ± 2.654
1.618PheTrp: 1.618 ± 1.109
4.854PheTyr: 4.854 ± 2.69
0.0PheXaa: 0.0 ± 0.0
Gly
1.618GlyAla: 1.618 ± 1.109
1.618GlyCys: 1.618 ± 1.109
4.854GlyAsp: 4.854 ± 2.69
4.854GlyGlu: 4.854 ± 2.027
0.0GlyPhe: 0.0 ± 0.0
4.854GlyGly: 4.854 ± 1.012
0.0GlyHis: 0.0 ± 0.0
1.618GlyIle: 1.618 ± 1.327
4.854GlyLys: 4.854 ± 2.027
1.618GlyLeu: 1.618 ± 1.109
0.0GlyMet: 0.0 ± 0.0
4.854GlyAsn: 4.854 ± 2.027
0.0GlyPro: 0.0 ± 0.0
0.0GlyGln: 0.0 ± 0.0
3.236GlyArg: 3.236 ± 1.749
9.709GlySer: 9.709 ± 1.78
6.472GlyThr: 6.472 ± 2.565
1.618GlyVal: 1.618 ± 1.327
0.0GlyTrp: 0.0 ± 0.0
8.091GlyTyr: 8.091 ± 2.877
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.618HisGlu: 1.618 ± 1.109
0.0HisPhe: 0.0 ± 0.0
3.236HisGly: 3.236 ± 0.953
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
4.854HisLeu: 4.854 ± 1.586
1.618HisMet: 1.618 ± 1.109
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.618HisArg: 1.618 ± 1.109
1.618HisSer: 1.618 ± 1.109
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
6.472IleAla: 6.472 ± 0.915
0.0IleCys: 0.0 ± 0.0
3.236IleAsp: 3.236 ± 0.953
3.236IleGlu: 3.236 ± 2.217
4.854IlePhe: 4.854 ± 2.69
1.618IleGly: 1.618 ± 1.327
1.618IleHis: 1.618 ± 1.109
1.618IleIle: 1.618 ± 1.903
4.854IleLys: 4.854 ± 3.326
8.091IleLeu: 8.091 ± 5.418
0.0IleMet: 0.0 ± 1.462
1.618IleAsn: 1.618 ± 1.327
0.0IlePro: 0.0 ± 0.0
6.472IleGln: 6.472 ± 3.784
4.854IleArg: 4.854 ± 2.225
9.709IleSer: 9.709 ± 6.967
0.0IleThr: 0.0 ± 0.0
6.472IleVal: 6.472 ± 1.907
1.618IleTrp: 1.618 ± 1.109
1.618IleTyr: 1.618 ± 1.109
0.0IleXaa: 0.0 ± 0.0
Lys
4.854LysAla: 4.854 ± 2.027
1.618LysCys: 1.618 ± 1.109
3.236LysAsp: 3.236 ± 0.953
0.0LysGlu: 0.0 ± 0.0
3.236LysPhe: 3.236 ± 2.654
3.236LysGly: 3.236 ± 2.217
0.0LysHis: 0.0 ± 0.0
3.236LysIle: 3.236 ± 1.749
6.472LysLys: 6.472 ± 3.291
6.472LysLeu: 6.472 ± 5.335
1.618LysMet: 1.618 ± 1.327
1.618LysAsn: 1.618 ± 1.327
3.236LysPro: 3.236 ± 2.217
1.618LysGln: 1.618 ± 1.327
3.236LysArg: 3.236 ± 0.953
8.091LysSer: 8.091 ± 3.619
1.618LysThr: 1.618 ± 1.109
8.091LysVal: 8.091 ± 0.493
3.236LysTrp: 3.236 ± 2.217
6.472LysTyr: 6.472 ± 1.907
0.0LysXaa: 0.0 ± 0.0
Leu
9.709LeuAla: 9.709 ± 0.658
0.0LeuCys: 0.0 ± 0.0
1.618LeuAsp: 1.618 ± 1.109
3.236LeuGlu: 3.236 ± 1.749
0.0LeuPhe: 0.0 ± 0.0
8.091LeuGly: 8.091 ± 4.993
0.0LeuHis: 0.0 ± 0.0
4.854LeuIle: 4.854 ± 3.484
11.327LeuLys: 11.327 ± 2.304
19.417LeuLeu: 19.417 ± 15.757
8.091LeuMet: 8.091 ± 4.795
4.854LeuAsn: 4.854 ± 3.581
3.236LeuPro: 3.236 ± 1.749
6.472LeuGln: 6.472 ± 2.896
4.854LeuArg: 4.854 ± 1.586
8.091LeuSer: 8.091 ± 2.742
4.854LeuThr: 4.854 ± 3.98
3.236LeuVal: 3.236 ± 1.749
1.618LeuTrp: 1.618 ± 1.903
3.236LeuTyr: 3.236 ± 1.915
0.0LeuXaa: 0.0 ± 0.0
Met
3.236MetAla: 3.236 ± 0.953
0.0MetCys: 0.0 ± 0.0
3.236MetAsp: 3.236 ± 2.217
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
4.854MetIle: 4.854 ± 2.027
3.236MetLys: 3.236 ± 2.217
8.091MetLeu: 8.091 ± 5.418
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
1.618MetGln: 1.618 ± 1.109
3.236MetArg: 3.236 ± 3.807
3.236MetSer: 3.236 ± 0.953
1.618MetThr: 1.618 ± 1.903
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.618AsnCys: 1.618 ± 1.109
3.236AsnAsp: 3.236 ± 2.217
1.618AsnGlu: 1.618 ± 1.109
0.0AsnPhe: 0.0 ± 0.0
3.236AsnGly: 3.236 ± 1.915
0.0AsnHis: 0.0 ± 0.0
0.0AsnIle: 0.0 ± 0.0
0.0AsnLys: 0.0 ± 0.0
6.472AsnLeu: 6.472 ± 1.584
0.0AsnMet: 0.0 ± 0.0
4.854AsnAsn: 4.854 ± 2.027
1.618AsnPro: 1.618 ± 1.327
4.854AsnGln: 4.854 ± 1.012
0.0AsnArg: 0.0 ± 0.0
4.854AsnSer: 4.854 ± 2.69
4.854AsnThr: 4.854 ± 2.027
1.618AsnVal: 1.618 ± 1.109
0.0AsnTrp: 0.0 ± 0.0
4.854AsnTyr: 4.854 ± 3.326
0.0AsnXaa: 0.0 ± 0.0
Pro
1.618ProAla: 1.618 ± 1.109
0.0ProCys: 0.0 ± 0.0
3.236ProAsp: 3.236 ± 1.749
1.618ProGlu: 1.618 ± 1.109
1.618ProPhe: 1.618 ± 1.327
3.236ProGly: 3.236 ± 0.953
0.0ProHis: 0.0 ± 0.0
0.0ProIle: 0.0 ± 0.0
1.618ProLys: 1.618 ± 1.109
3.236ProLeu: 3.236 ± 0.953
4.854ProMet: 4.854 ± 1.345
3.236ProAsn: 3.236 ± 2.217
0.0ProPro: 0.0 ± 0.0
3.236ProGln: 3.236 ± 0.953
3.236ProArg: 3.236 ± 3.807
0.0ProSer: 0.0 ± 0.0
1.618ProThr: 1.618 ± 1.109
1.618ProVal: 1.618 ± 1.109
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.854GlnAla: 4.854 ± 2.027
0.0GlnCys: 0.0 ± 0.0
1.618GlnAsp: 1.618 ± 1.109
1.618GlnGlu: 1.618 ± 1.109
0.0GlnPhe: 0.0 ± 0.0
4.854GlnGly: 4.854 ± 2.027
0.0GlnHis: 0.0 ± 0.0
4.854GlnIle: 4.854 ± 2.027
1.618GlnLys: 1.618 ± 1.903
4.854GlnLeu: 4.854 ± 5.71
0.0GlnMet: 0.0 ± 0.0
1.618GlnAsn: 1.618 ± 1.109
0.0GlnPro: 0.0 ± 0.0
4.854GlnGln: 4.854 ± 3.581
1.618GlnArg: 1.618 ± 1.109
4.854GlnSer: 4.854 ± 3.98
1.618GlnThr: 1.618 ± 1.109
6.472GlnVal: 6.472 ± 3.291
0.0GlnTrp: 0.0 ± 0.0
1.618GlnTyr: 1.618 ± 1.903
0.0GlnXaa: 0.0 ± 0.0
Arg
4.854ArgAla: 4.854 ± 1.586
1.618ArgCys: 1.618 ± 1.109
6.472ArgAsp: 6.472 ± 5.335
0.0ArgGlu: 0.0 ± 0.0
1.618ArgPhe: 1.618 ± 1.109
1.618ArgGly: 1.618 ± 1.109
3.236ArgHis: 3.236 ± 2.217
1.618ArgIle: 1.618 ± 1.327
1.618ArgLys: 1.618 ± 1.903
6.472ArgLeu: 6.472 ± 3.498
1.618ArgMet: 1.618 ± 1.327
6.472ArgAsn: 6.472 ± 2.896
1.618ArgPro: 1.618 ± 1.109
0.0ArgGln: 0.0 ± 0.0
3.236ArgArg: 3.236 ± 2.217
1.618ArgSer: 1.618 ± 1.327
3.236ArgThr: 3.236 ± 3.807
6.472ArgVal: 6.472 ± 3.784
3.236ArgTrp: 3.236 ± 2.217
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.472SerAla: 6.472 ± 1.584
0.0SerCys: 0.0 ± 0.0
3.236SerAsp: 3.236 ± 1.915
0.0SerGlu: 0.0 ± 0.0
3.236SerPhe: 3.236 ± 2.654
3.236SerGly: 3.236 ± 0.953
0.0SerHis: 0.0 ± 0.0
11.327SerIle: 11.327 ± 1.579
4.854SerLys: 4.854 ± 1.586
8.091SerLeu: 8.091 ± 4.993
4.854SerMet: 4.854 ± 1.586
3.236SerAsn: 3.236 ± 2.217
0.0SerPro: 0.0 ± 0.0
6.472SerGln: 6.472 ± 0.915
4.854SerArg: 4.854 ± 1.012
1.618SerSer: 1.618 ± 1.327
3.236SerThr: 3.236 ± 2.217
8.091SerVal: 8.091 ± 4.993
0.0SerTrp: 0.0 ± 0.0
1.618SerTyr: 1.618 ± 1.109
0.0SerXaa: 0.0 ± 0.0
Thr
4.854ThrAla: 4.854 ± 2.69
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
1.618ThrGlu: 1.618 ± 1.109
0.0ThrPhe: 0.0 ± 0.0
4.854ThrGly: 4.854 ± 3.326
0.0ThrHis: 0.0 ± 0.0
3.236ThrIle: 3.236 ± 1.915
4.854ThrLys: 4.854 ± 1.012
6.472ThrLeu: 6.472 ± 2.565
3.236ThrMet: 3.236 ± 1.794
0.0ThrAsn: 0.0 ± 0.0
3.236ThrPro: 3.236 ± 0.953
4.854ThrGln: 4.854 ± 3.98
6.472ThrArg: 6.472 ± 3.291
3.236ThrSer: 3.236 ± 0.953
3.236ThrThr: 3.236 ± 2.217
3.236ThrVal: 3.236 ± 0.953
1.618ThrTrp: 1.618 ± 1.903
3.236ThrTyr: 3.236 ± 2.217
0.0ThrXaa: 0.0 ± 0.0
Val
6.472ValAla: 6.472 ± 2.896
0.0ValCys: 0.0 ± 0.0
4.854ValAsp: 4.854 ± 3.326
4.854ValGlu: 4.854 ± 1.586
1.618ValPhe: 1.618 ± 1.327
8.091ValGly: 8.091 ± 6.634
1.618ValHis: 1.618 ± 1.327
8.091ValIle: 8.091 ± 0.493
6.472ValLys: 6.472 ± 3.291
3.236ValLeu: 3.236 ± 2.654
0.0ValMet: 0.0 ± 0.0
4.854ValAsn: 4.854 ± 2.027
3.236ValPro: 3.236 ± 1.915
0.0ValGln: 0.0 ± 0.0
0.0ValArg: 0.0 ± 0.0
1.618ValSer: 1.618 ± 1.109
4.854ValThr: 4.854 ± 1.012
8.091ValVal: 8.091 ± 2.877
0.0ValTrp: 0.0 ± 0.0
3.236ValTyr: 3.236 ± 2.217
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.618TrpPhe: 1.618 ± 1.109
1.618TrpGly: 1.618 ± 1.109
0.0TrpHis: 0.0 ± 0.0
1.618TrpIle: 1.618 ± 1.109
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.618TrpMet: 1.618 ± 1.109
0.0TrpAsn: 0.0 ± 0.0
1.618TrpPro: 1.618 ± 1.109
1.618TrpGln: 1.618 ± 1.109
1.618TrpArg: 1.618 ± 1.903
0.0TrpSer: 0.0 ± 0.0
1.618TrpThr: 1.618 ± 1.903
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.854TyrAla: 4.854 ± 2.027
4.854TyrCys: 4.854 ± 3.326
3.236TyrAsp: 3.236 ± 0.953
0.0TyrGlu: 0.0 ± 0.0
0.0TyrPhe: 0.0 ± 0.0
1.618TyrGly: 1.618 ± 1.327
0.0TyrHis: 0.0 ± 0.0
6.472TyrIle: 6.472 ± 4.434
3.236TyrLys: 3.236 ± 0.953
4.854TyrLeu: 4.854 ± 1.012
0.0TyrMet: 0.0 ± 0.0
1.618TyrAsn: 1.618 ± 1.109
4.854TyrPro: 4.854 ± 2.225
1.618TyrGln: 1.618 ± 1.109
3.236TyrArg: 3.236 ± 1.915
3.236TyrSer: 3.236 ± 0.953
4.854TyrThr: 4.854 ± 2.027
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
1.618TyrTyr: 1.618 ± 1.327
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (619 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski