Amino acid dipepetide frequency for Candidatus Magnetobacterium bavaricum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.694AlaAla: 5.694 ± 0.084	0.915AlaCys: 0.915 ± 0.023	4.004AlaAsp: 4.004 ± 0.051	3.88AlaGlu: 3.88 ± 0.056	2.934AlaPhe: 2.934 ± 0.043	5.284AlaGly: 5.284 ± 0.073	1.289AlaHis: 1.289 ± 0.025	6.157AlaIle: 6.157 ± 0.061	3.812AlaLys: 3.812 ± 0.056	7.602AlaLeu: 7.602 ± 0.081	2.165AlaMet: 2.165 ± 0.038	2.81AlaAsn: 2.81 ± 0.041	2.182AlaPro: 2.182 ± 0.041	2.136AlaGln: 2.136 ± 0.044	3.49AlaArg: 3.49 ± 0.044	4.482AlaSer: 4.482 ± 0.061	4.224AlaThr: 4.224 ± 0.067	5.486AlaVal: 5.486 ± 0.068	0.744AlaTrp: 0.744 ± 0.026	2.504AlaTyr: 2.504 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.756CysAla: 0.756 ± 0.021	0.251CysCys: 0.251 ± 0.015	0.673CysAsp: 0.673 ± 0.024	0.536CysGlu: 0.536 ± 0.018	0.545CysPhe: 0.545 ± 0.02	1.055CysGly: 1.055 ± 0.029	0.386CysHis: 0.386 ± 0.019	0.923CysIle: 0.923 ± 0.022	0.723CysLys: 0.723 ± 0.025	1.279CysLeu: 1.279 ± 0.029	0.337CysMet: 0.337 ± 0.015	0.629CysAsn: 0.629 ± 0.022	0.605CysPro: 0.605 ± 0.024	0.418CysGln: 0.418 ± 0.016	0.697CysArg: 0.697 ± 0.021	0.904CysSer: 0.904 ± 0.028	0.781CysThr: 0.781 ± 0.03	0.892CysVal: 0.892 ± 0.026	0.13CysTrp: 0.13 ± 0.009	0.494CysTyr: 0.494 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	4.118AspAla: 4.118 ± 0.057	0.711AspCys: 0.711 ± 0.022	3.406AspAsp: 3.406 ± 0.053	3.388AspGlu: 3.388 ± 0.051	2.837AspPhe: 2.837 ± 0.05	4.708AspGly: 4.708 ± 0.103	0.83AspHis: 0.83 ± 0.022	5.989AspIle: 5.989 ± 0.066	4.121AspLys: 4.121 ± 0.056	4.589AspLeu: 4.589 ± 0.058	1.669AspMet: 1.669 ± 0.032	2.99AspAsn: 2.99 ± 0.048	1.888AspPro: 1.888 ± 0.037	1.015AspGln: 1.015 ± 0.024	2.64AspArg: 2.64 ± 0.045	3.426AspSer: 3.426 ± 0.054	3.441AspThr: 3.441 ± 0.052	4.626AspVal: 4.626 ± 0.069	0.664AspTrp: 0.664 ± 0.023	2.259AspTyr: 2.259 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	4.537GluAla: 4.537 ± 0.066	0.551GluCys: 0.551 ± 0.019	3.185GluAsp: 3.185 ± 0.055	3.673GluGlu: 3.673 ± 0.058	2.365GluPhe: 2.365 ± 0.038	3.97GluGly: 3.97 ± 0.06	1.159GluHis: 1.159 ± 0.029	4.696GluIle: 4.696 ± 0.071	3.852GluLys: 3.852 ± 0.06	6.033GluLeu: 6.033 ± 0.082	1.676GluMet: 1.676 ± 0.035	2.108GluAsn: 2.108 ± 0.032	1.732GluPro: 1.732 ± 0.032	1.924GluGln: 1.924 ± 0.037	3.269GluArg: 3.269 ± 0.051	2.886GluSer: 2.886 ± 0.041	3.143GluThr: 3.143 ± 0.049	4.107GluVal: 4.107 ± 0.056	0.498GluTrp: 0.498 ± 0.018	1.772GluTyr: 1.772 ± 0.037	0.0GluXaa: 0.0 ± 0.0
Phe	2.631PheAla: 2.631 ± 0.038	0.577PheCys: 0.577 ± 0.022	2.679PheAsp: 2.679 ± 0.044	2.156PheGlu: 2.156 ± 0.04	2.042PhePhe: 2.042 ± 0.046	2.513PheGly: 2.513 ± 0.044	0.726PheHis: 0.726 ± 0.022	3.261PheIle: 3.261 ± 0.054	2.689PheLys: 2.689 ± 0.041	3.84PheLeu: 3.84 ± 0.059	1.197PheMet: 1.197 ± 0.029	2.188PheAsn: 2.188 ± 0.043	1.284PhePro: 1.284 ± 0.028	0.964PheGln: 0.964 ± 0.023	1.754PheArg: 1.754 ± 0.031	2.873PheSer: 2.873 ± 0.05	2.6PheThr: 2.6 ± 0.05	2.937PheVal: 2.937 ± 0.048	0.42PheTrp: 0.42 ± 0.016	1.734PheTyr: 1.734 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.703GlyAla: 4.703 ± 0.067	1.088GlyCys: 1.088 ± 0.032	4.386GlyAsp: 4.386 ± 0.097	3.385GlyGlu: 3.385 ± 0.048	3.046GlyPhe: 3.046 ± 0.045	5.059GlyGly: 5.059 ± 0.075	1.507GlyHis: 1.507 ± 0.033	5.529GlyIle: 5.529 ± 0.061	4.934GlyLys: 4.934 ± 0.062	6.443GlyLeu: 6.443 ± 0.075	2.075GlyMet: 2.075 ± 0.041	3.204GlyAsn: 3.204 ± 0.066	1.425GlyPro: 1.425 ± 0.036	2.401GlyGln: 2.401 ± 0.051	3.434GlyArg: 3.434 ± 0.047	4.526GlySer: 4.526 ± 0.078	4.316GlyThr: 4.316 ± 0.1	5.439GlyVal: 5.439 ± 0.085	0.803GlyTrp: 0.803 ± 0.028	2.88GlyTyr: 2.88 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	1.178HisAla: 1.178 ± 0.027	0.316HisCys: 0.316 ± 0.015	1.057HisAsp: 1.057 ± 0.028	1.05HisGlu: 1.05 ± 0.026	0.749HisPhe: 0.749 ± 0.021	1.348HisGly: 1.348 ± 0.029	0.49HisHis: 0.49 ± 0.022	1.465HisIle: 1.465 ± 0.032	1.168HisLys: 1.168 ± 0.032	1.775HisLeu: 1.775 ± 0.035	0.52HisMet: 0.52 ± 0.019	0.886HisAsn: 0.886 ± 0.024	1.067HisPro: 1.067 ± 0.03	0.603HisGln: 0.603 ± 0.018	1.127HisArg: 1.127 ± 0.024	1.148HisSer: 1.148 ± 0.028	1.133HisThr: 1.133 ± 0.029	1.231HisVal: 1.231 ± 0.028	0.225HisTrp: 0.225 ± 0.012	0.71HisTyr: 0.71 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.964IleAla: 5.964 ± 0.079	0.872IleCys: 0.872 ± 0.022	5.011IleAsp: 5.011 ± 0.06	5.173IleGlu: 5.173 ± 0.074	2.635IlePhe: 2.635 ± 0.047	4.894IleGly: 4.894 ± 0.057	1.325IleHis: 1.325 ± 0.029	5.188IleIle: 5.188 ± 0.077	5.458IleLys: 5.458 ± 0.071	6.135IleLeu: 6.135 ± 0.072	1.768IleMet: 1.768 ± 0.039	3.702IleAsn: 3.702 ± 0.062	2.957IlePro: 2.957 ± 0.042	1.886IleGln: 1.886 ± 0.036	3.749IleArg: 3.749 ± 0.05	5.294IleSer: 5.294 ± 0.061	4.737IleThr: 4.737 ± 0.062	5.53IleVal: 5.53 ± 0.064	0.717IleTrp: 0.717 ± 0.026	2.372IleTyr: 2.372 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	4.625LysAla: 4.625 ± 0.056	0.598LysCys: 0.598 ± 0.023	4.412LysAsp: 4.412 ± 0.055	4.651LysGlu: 4.651 ± 0.067	1.722LysPhe: 1.722 ± 0.04	4.699LysGly: 4.699 ± 0.06	1.26LysHis: 1.26 ± 0.029	4.335LysIle: 4.335 ± 0.065	4.843LysLys: 4.843 ± 0.065	4.889LysLeu: 4.889 ± 0.074	1.683LysMet: 1.683 ± 0.029	2.892LysAsn: 2.892 ± 0.051	2.35LysPro: 2.35 ± 0.043	2.066LysGln: 2.066 ± 0.048	3.33LysArg: 3.33 ± 0.057	3.816LysSer: 3.816 ± 0.056	4.16LysThr: 4.16 ± 0.057	3.997LysVal: 3.997 ± 0.055	0.646LysTrp: 0.646 ± 0.022	2.169LysTyr: 2.169 ± 0.039	0.0LysXaa: 0.0 ± 0.0
Leu	6.298LeuAla: 6.298 ± 0.082	1.376LeuCys: 1.376 ± 0.036	4.711LeuAsp: 4.711 ± 0.059	4.845LeuGlu: 4.845 ± 0.069	3.795LeuPhe: 3.795 ± 0.058	5.324LeuGly: 5.324 ± 0.068	1.818LeuHis: 1.818 ± 0.038	6.436LeuIle: 6.436 ± 0.074	6.816LeuLys: 6.816 ± 0.075	9.045LeuLeu: 9.045 ± 0.097	2.789LeuMet: 2.789 ± 0.045	4.5LeuAsn: 4.5 ± 0.06	4.091LeuPro: 4.091 ± 0.058	3.081LeuGln: 3.081 ± 0.049	5.324LeuArg: 5.324 ± 0.07	7.252LeuSer: 7.252 ± 0.076	5.902LeuThr: 5.902 ± 0.058	5.675LeuVal: 5.675 ± 0.072	1.197LeuTrp: 1.197 ± 0.038	3.428LeuTyr: 3.428 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.396MetAla: 2.396 ± 0.043	0.297MetCys: 0.297 ± 0.015	1.646MetAsp: 1.646 ± 0.034	1.509MetGlu: 1.509 ± 0.037	1.076MetPhe: 1.076 ± 0.026	1.733MetGly: 1.733 ± 0.035	0.496MetHis: 0.496 ± 0.019	1.669MetIle: 1.669 ± 0.035	1.699MetLys: 1.699 ± 0.032	2.81MetLeu: 2.81 ± 0.036	0.653MetMet: 0.653 ± 0.021	1.06MetAsn: 1.06 ± 0.027	1.432MetPro: 1.432 ± 0.029	0.944MetGln: 0.944 ± 0.024	1.358MetArg: 1.358 ± 0.031	1.922MetSer: 1.922 ± 0.032	1.681MetThr: 1.681 ± 0.036	1.811MetVal: 1.811 ± 0.035	0.271MetTrp: 0.271 ± 0.013	0.787MetTyr: 0.787 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.207AsnAla: 3.207 ± 0.046	0.55AsnCys: 0.55 ± 0.022	2.535AsnAsp: 2.535 ± 0.037	2.282AsnGlu: 2.282 ± 0.038	1.467AsnPhe: 1.467 ± 0.031	3.426AsnGly: 3.426 ± 0.084	0.794AsnHis: 0.794 ± 0.022	3.745AsnIle: 3.745 ± 0.052	2.848AsnLys: 2.848 ± 0.05	3.931AsnLeu: 3.931 ± 0.048	1.128AsnMet: 1.128 ± 0.03	2.307AsnAsn: 2.307 ± 0.046	2.088AsnPro: 2.088 ± 0.036	1.094AsnGln: 1.094 ± 0.024	2.129AsnArg: 2.129 ± 0.041	2.73AsnSer: 2.73 ± 0.051	2.843AsnThr: 2.843 ± 0.053	3.213AsnVal: 3.213 ± 0.045	0.55AsnTrp: 0.55 ± 0.024	1.596AsnTyr: 1.596 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	2.65ProAla: 2.65 ± 0.047	0.505ProCys: 0.505 ± 0.021	2.495ProAsp: 2.495 ± 0.045	2.442ProGlu: 2.442 ± 0.046	1.744ProPhe: 1.744 ± 0.032	2.475ProGly: 2.475 ± 0.043	0.78ProHis: 0.78 ± 0.027	2.415ProIle: 2.415 ± 0.044	1.83ProLys: 1.83 ± 0.033	3.78ProLeu: 3.78 ± 0.053	0.988ProMet: 0.988 ± 0.024	1.508ProAsn: 1.508 ± 0.035	1.881ProPro: 1.881 ± 0.053	1.437ProGln: 1.437 ± 0.035	1.447ProArg: 1.447 ± 0.036	2.527ProSer: 2.527 ± 0.047	2.463ProThr: 2.463 ± 0.074	3.098ProVal: 3.098 ± 0.048	0.38ProTrp: 0.38 ± 0.017	1.443ProTyr: 1.443 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	2.124GlnAla: 2.124 ± 0.036	0.386GlnCys: 0.386 ± 0.016	1.712GlnAsp: 1.712 ± 0.033	2.162GlnGlu: 2.162 ± 0.042	0.988GlnPhe: 0.988 ± 0.029	2.124GlnGly: 2.124 ± 0.044	0.656GlnHis: 0.656 ± 0.023	1.924GlnIle: 1.924 ± 0.039	1.867GlnLys: 1.867 ± 0.039	2.779GlnLeu: 2.779 ± 0.047	0.877GlnMet: 0.877 ± 0.027	1.175GlnAsn: 1.175 ± 0.028	1.2GlnPro: 1.2 ± 0.031	1.387GlnGln: 1.387 ± 0.036	2.169GlnArg: 2.169 ± 0.041	1.915GlnSer: 1.915 ± 0.035	1.799GlnThr: 1.799 ± 0.037	1.912GlnVal: 1.912 ± 0.038	0.53GlnTrp: 0.53 ± 0.02	1.154GlnTyr: 1.154 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	3.286ArgAla: 3.286 ± 0.044	0.674ArgCys: 0.674 ± 0.022	3.024ArgAsp: 3.024 ± 0.046	3.119ArgGlu: 3.119 ± 0.051	2.372ArgPhe: 2.372 ± 0.039	3.224ArgGly: 3.224 ± 0.045	1.308ArgHis: 1.308 ± 0.031	3.486ArgIle: 3.486 ± 0.051	2.857ArgLys: 2.857 ± 0.047	5.5ArgLeu: 5.5 ± 0.074	1.349ArgMet: 1.349 ± 0.026	1.994ArgAsn: 1.994 ± 0.031	1.868ArgPro: 1.868 ± 0.033	2.216ArgGln: 2.216 ± 0.044	2.805ArgArg: 2.805 ± 0.052	2.646ArgSer: 2.646 ± 0.041	2.291ArgThr: 2.291 ± 0.04	3.349ArgVal: 3.349 ± 0.042	0.538ArgTrp: 0.538 ± 0.02	2.182ArgTyr: 2.182 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	4.65SerAla: 4.65 ± 0.049	0.91SerCys: 0.91 ± 0.024	3.908SerAsp: 3.908 ± 0.061	3.438SerGlu: 3.438 ± 0.05	2.817SerPhe: 2.817 ± 0.053	5.67SerGly: 5.67 ± 0.111	1.133SerHis: 1.133 ± 0.025	4.676SerIle: 4.676 ± 0.066	3.579SerLys: 3.579 ± 0.043	6.147SerLeu: 6.147 ± 0.066	1.776SerMet: 1.776 ± 0.032	2.764SerAsn: 2.764 ± 0.054	2.644SerPro: 2.644 ± 0.048	1.669SerGln: 1.669 ± 0.033	2.978SerArg: 2.978 ± 0.046	4.605SerSer: 4.605 ± 0.083	3.907SerThr: 3.907 ± 0.062	4.865SerVal: 4.865 ± 0.062	0.665SerTrp: 0.665 ± 0.024	2.28SerTyr: 2.28 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	4.537ThrAla: 4.537 ± 0.084	0.778ThrCys: 0.778 ± 0.028	3.472ThrAsp: 3.472 ± 0.051	3.087ThrGlu: 3.087 ± 0.045	2.392ThrPhe: 2.392 ± 0.042	5.161ThrGly: 5.161 ± 0.094	1.137ThrHis: 1.137 ± 0.03	4.561ThrIle: 4.561 ± 0.061	3.02ThrLys: 3.02 ± 0.045	5.832ThrLeu: 5.832 ± 0.064	1.484ThrMet: 1.484 ± 0.032	2.273ThrAsn: 2.273 ± 0.037	3.181ThrPro: 3.181 ± 0.08	1.731ThrGln: 1.731 ± 0.036	2.381ThrArg: 2.381 ± 0.037	4.011ThrSer: 4.011 ± 0.074	3.97ThrThr: 3.97 ± 0.081	4.636ThrVal: 4.636 ± 0.072	0.709ThrTrp: 0.709 ± 0.029	2.028ThrTyr: 2.028 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	5.421ValAla: 5.421 ± 0.074	1.003ValCys: 1.003 ± 0.026	4.096ValAsp: 4.096 ± 0.054	3.932ValGlu: 3.932 ± 0.056	3.475ValPhe: 3.475 ± 0.052	4.71ValGly: 4.71 ± 0.076	1.135ValHis: 1.135 ± 0.03	5.656ValIle: 5.656 ± 0.063	4.236ValLys: 4.236 ± 0.056	6.651ValLeu: 6.651 ± 0.08	1.84ValMet: 1.84 ± 0.032	3.115ValAsn: 3.115 ± 0.047	2.545ValPro: 2.545 ± 0.042	1.94ValGln: 1.94 ± 0.039	3.475ValArg: 3.475 ± 0.044	5.131ValSer: 5.131 ± 0.064	4.372ValThr: 4.372 ± 0.087	5.943ValVal: 5.943 ± 0.075	0.783ValTrp: 0.783 ± 0.032	2.601ValTyr: 2.601 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.583TrpAla: 0.583 ± 0.017	0.121TrpCys: 0.121 ± 0.009	0.586TrpAsp: 0.586 ± 0.028	0.468TrpGlu: 0.468 ± 0.017	0.5TrpPhe: 0.5 ± 0.02	0.711TrpGly: 0.711 ± 0.029	0.29TrpHis: 0.29 ± 0.015	0.69TrpIle: 0.69 ± 0.022	0.6TrpLys: 0.6 ± 0.022	1.329TrpLeu: 1.329 ± 0.033	0.273TrpMet: 0.273 ± 0.012	0.418TrpAsn: 0.418 ± 0.016	0.407TrpPro: 0.407 ± 0.018	0.915TrpGln: 0.915 ± 0.047	0.653TrpArg: 0.653 ± 0.025	0.803TrpSer: 0.803 ± 0.03	0.542TrpThr: 0.542 ± 0.021	0.614TrpVal: 0.614 ± 0.023	0.153TrpTrp: 0.153 ± 0.011	0.356TrpTyr: 0.356 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.436TyrAla: 2.436 ± 0.035	0.536TyrCys: 0.536 ± 0.021	2.318TyrAsp: 2.318 ± 0.047	1.957TyrGlu: 1.957 ± 0.035	1.563TyrPhe: 1.563 ± 0.034	2.492TyrGly: 2.492 ± 0.043	0.726TyrHis: 0.726 ± 0.022	2.565TyrIle: 2.565 ± 0.041	2.194TyrLys: 2.194 ± 0.037	3.31TyrLeu: 3.31 ± 0.049	1.005TyrMet: 1.005 ± 0.027	1.939TyrAsn: 1.939 ± 0.043	1.46TyrPro: 1.46 ± 0.031	1.012TyrGln: 1.012 ± 0.021	1.881TyrArg: 1.881 ± 0.033	2.186TyrSer: 2.186 ± 0.044	2.078TyrThr: 2.078 ± 0.039	2.7TyrVal: 2.7 ± 0.048	0.389TyrTrp: 0.389 ± 0.014	1.413TyrTyr: 1.413 ± 0.034	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6447 proteins (1584456 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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